Autosampler

Abstract

The present application provides an automatic sampler, comprising at least two relatively arranged brackets, a first transmission shaft, a fixed bracket, an injection needle, a sample container, a bottle presser assembly and a first driving mechanism. The bottle presser assembly is connected to the fixed bracket and can move up and down relative to the first transmission shaft. The bottle presser assembly can be located at a first position or a second position. In the first position, the bottle presser assembly is separated from the sample container, and in the second position, the bottle presser assembly is pressed against the top surface of the sample container; the first driving mechanism is used to drive the first transmission shaft to rotate, drive the fixed bracket and the bottle presser assembly to move up and down, and move the bottle presser assembly between the first position and the second position. When the bottle presser assembly is in the second position, the first transmission shaft is driven to rotate, and the fixed bracket is driven to move up and down relative to the bottle presser assembly, so that the injection needle is inserted into or pulled out of the sample container. Functional requirements are met and costs are reduced.

Description

Technical Field

[0001] The present application relates to the field of automation technology, and in particular to an automatic sample injector. Background Art

[0002] In chromatographic experimental analysis, the device that can quantitatively deliver samples into the chromatographic column is called an injector. Injectors are divided into two types: manual injectors and automatic injectors. An automatic injector is an intelligent and automated injection instrument. You only need to set the injection parameters and put in the sample to be tested to complete the automatic injection process. In the related technology, two sets of transmission mechanisms are used to realize the movement of the injection needle and the bottle press assembly, which is costly. Summary of the invention

[0003] The present application provides an automatic sample injector with lower cost.

[0004] The present application provides an automatic sample injector, comprising:

[0005] At least two brackets arranged opposite to each other, the brackets extending up and down;

[0006] A first transmission shaft, disposed between at least two of the brackets;

[0007] a fixed bracket movably connected to the first transmission shaft;

[0008] An injection needle, fixed to the fixed bracket;

[0009] A sample container is arranged below the fixed bracket;

[0010] a bottle press assembly connected to the fixed bracket and movable up and down relative to the first transmission shaft, wherein the bottle press assembly can be located at a first position or a second position, wherein in the first position, the bottle press assembly is separated from the sample container, and in the second position, the bottle press assembly is pressed against the top surface of the sample container; and

[0011] A first driving mechanism is disposed on the bracket and connected to the first transmission shaft; the first driving mechanism is used to drive the first transmission shaft to rotate, drive the fixed bracket and the bottle press assembly to move up and down, and make the bottle press assembly move between the first position and the second position; and when the bottle press assembly is in the second position, the first transmission shaft is driven to rotate, drive the fixed bracket to move up and down relative to the bottle press assembly, and make the injection needle inserted into or pulled out of the sample container.

[0012] Optionally, the bottle pressing assembly includes a bottle pressing member, a positioning shaft and a first elastic member; the positioning shaft extends up and down, the bottle pressing member is arranged at the bottom of the positioning shaft, the first elastic member is sleeved on the positioning shaft, and the fixing bracket is arranged on the top of the first elastic member and connected to the positioning shaft;

[0013] When the bottle pressing assembly is in the first position, the bottle pressing member is separated from the sample container, the fixed bracket, the top of the first elastic member and the top of the positioning shaft are connected, and the first driving mechanism is used to drive the first transmission shaft to rotate, thereby driving the fixed bracket, the bottle pressing member, the positioning shaft and the first elastic member to move up and down together;

[0014] When the bottle press assembly is in the second position, the bottle press member presses against the top surface of the sample container, the first driving mechanism is used to drive the first transmission shaft to rotate, and drive the fixed bracket to move up and down relative to the positioning shaft, the top of the fixed bracket and the first elastic member are separated from the top of the positioning shaft, and the first elastic member elastically deforms up and down to interact with the fixed bracket.

[0015] Optionally, the bottle pressing assembly further comprises a grating and a light triggering member, wherein the grating is fixedly arranged on the top of the positioning shaft, and the light triggering member is arranged on the top of the first elastic member and is fixedly connected to the fixing bracket and the top of the first elastic member;

[0016] When the bottle pressing assembly is in the first position, the optical trigger is connected to the grating, the fixed bracket, the top of the first elastic member and the top of the positioning shaft are connected, and the first driving mechanism is used to drive the first transmission shaft to rotate, thereby driving the fixed bracket, the optical trigger and the grating to move up and down together;

[0017] When the bottle press assembly is in the second position, the first driving mechanism is used to drive the first transmission shaft to rotate, thereby driving the fixed bracket and the light triggering component to move up and down together relative to the grating, and the light triggering component is separated from the grating. The grating is used to detect the movement distance of the fixed bracket relative to the positioning shaft, so as to detect the movement distance of the injection needle.

[0018] Optionally, the bottle press assembly further includes a first fixing member, which is disposed on the top of the first elastic member and fixedly connected to the fixing bracket; and the light triggering member is fixed to the first fixing member.

[0019] Optionally, the fixed bracket includes a bracket slot extending upward and downward, the first fixing piece is provided with a through hole extending upward and downward, the positioning shaft is passed through the through hole, the top of the bracket slot is pressed against the top surface of the first fixing piece, the bottom surface of the first fixing piece is pressed against the first elastic piece, and the side surface of the first fixing piece is engaged with the side wall of the bracket slot; when the bottle press assembly is in the second position, the first driving mechanism is used to drive the first transmission shaft to rotate, thereby driving the fixed bracket and the first fixing piece to move up and down together relative to the positioning shaft.

[0020] Optionally, the bottle press assembly further includes a second fixing member fixedly disposed on the top of the positioning shaft, and the grating is disposed on the second fixing member.

[0021] Optionally, the sample container includes an injection bottle, which is arranged below the bottle presser assembly; the injection bottle includes an outer shell, a bottle cap arranged on the outer shell, and an injection seat arranged in the outer shell; when the bottle presser assembly is in the second position, the bottle pressing member presses against the top surface of the bottle cap, and the first driving mechanism is used to drive the first transmission shaft to rotate, drive the fixed bracket to press the first elastic member to move up and down relative to the positioning shaft, and drive the injection needle to move up and down relative to the bottle cap to insert or remove the injection seat.

[0022] Optionally, the injection bottle also includes a second elastic member and a pressure sensor disposed in the outer shell, the pressure sensor is disposed at the bottom of the outer shell, and the pressure sensor is elastically connected to the injection seat through the second elastic member; when the bottle presser assembly is in the second position, the bottle presser is pressed against the top surface of the bottle cap, and when the injection needle moves downward relative to the bottle cap and is inserted into the injection seat, the pressure sensor is used to detect the pressure of the injection needle exerted on the injection seat, and the automatic sampler includes a controller, which is used to control the first drive mechanism to stop driving the first transmission shaft to rotate when the pressure sensor detects that the pressure reaches a pressure threshold.

[0023] Optionally, the automatic sampler further comprises a sample tray assembly, the sample container comprises a sample suction bottle, and the sample tray assembly accommodates the sample suction bottle; when the bottle press assembly is in the second position, the injection needle extends into the sample suction bottle to suction the sample.

[0024] Optionally, the fixed bracket includes a locking needle groove and an elastic component fixedly connected to the locking needle groove, the elastic component clamps the injection needle so that the injection needle is fixed in the locking needle groove, and can be elastically deformed relative to the locking needle groove to allow the injection needle to be inserted or removed.

[0025] Optionally, the fixing bracket is an integrated structure.

[0026] In the automatic sampler of the embodiment of the present application, the bottle presser assembly is connected to the fixed bracket, and the first driving mechanism drives the first transmission shaft to rotate, driving the fixed bracket and the bottle presser assembly to move up and down together; when the bottle presser assembly is in the second position, the first driving mechanism drives the first transmission shaft to rotate, driving the fixed bracket to move up and down relative to the bottle presser assembly, so that the injection needle can be inserted into or pulled out of the sample container. In this arrangement, the same first driving mechanism is used to drive the first rotating shaft to rotate, driving the fixed bracket to move up and down, and driving the bottle presser assembly to move up and down, which meets the functional requirements, reduces the number of driving mechanisms and transmission mechanisms, and reduces costs. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] Figure 1 Shown is a schematic structural diagram of an embodiment of the automatic sample injector of the present application.

[0028] Figure 2 Shown is a schematic structural diagram of a front view of a fixing bracket for the injection needle of the present application.

[0029] Figure 3 Shown Figure 2 A schematic structural diagram of the rear view perspective of the fixed bracket of the injection needle shown.

[0030] Figure 4 Shown Figure 2 A schematic side cross-sectional view of a fixing bracket for a syringe needle is shown.

[0031] Figure 5 Shown Figure 2 The bottom view of the fixed bracket of the injection needle is shown.

[0032] Figure 6 Shown is a schematic structural diagram of the front view of the injection needle of the present application being inserted into the fixed bracket.

[0033] Figure 7 Shown Figure 6 A schematic cross-sectional view of a side elevation view of a syringe being inserted into a mounting bracket is shown.

[0034] Figure 8 Shown Figure 6 A schematic cross-sectional view from the bottom showing a needle being inserted into a mounting bracket.

[0035] Fig. 9 Shown Figure 6 The fixing bracket of the injection needle shown is fixed to the schematic cross-sectional view of the transmission mechanism from a side view.

[0036] Fig.10 Shown Figure 6The fixing bracket of the injection needle shown is a schematic structural diagram from a bottom view in which the fixing bracket of the injection needle is fixed to the transmission mechanism.

[0037] Fig.11 Shown Figure 1 A partial structural schematic diagram of the automatic sampler shown in the front view.

[0038] Fig.12 Shown Figure 1 A partial structural schematic diagram of the automatic sampler shown in the rear view.

[0039] Fig.13 The exploded view is shown when the first optical axis fixing member of the automatic sample injector of the present application is not assembled to the bracket.

[0040] Fig.14 Shown Fig.13 The structure diagram of the first optical axis fixing member of the automatic sampler shown is a side view of the unassembled bracket.

[0041] Fig.15 Shown Fig.13 The schematic diagram of the structure of the first optical axis fixing part of the automatic sample injector is assembled on the bracket.

[0042] Fig.16 The exploded view shows the second optical axis fixing member of the automatic sample injector of the present application not being assembled to the bracket.

[0043] Fig.17 Shown Fig.16 The schematic diagram of the structure of the second optical axis fixing piece of the automatic sampler shown is a side view of the unassembled bracket.

[0044] Fig.18 Shown Fig.16 The schematic diagram of the structure of the second optical axis fixing part of the automatic sample injector is assembled on the bracket.

[0045] Fig.19 Shown Figure 1 A partial structural schematic diagram of the automatic sampler shown in the front view.

[0046] Fig. 20 Shown Fig.19 The schematic diagram of the structure of the bottle press assembly of the automatic sampler when it is in the first position.

[0047] Fig.21 Shown Fig.19 The schematic diagram of the structure of the bottle press assembly of the automatic sampler when it is in the second position.

[0048] Fig. 22 Shown Fig.19 The schematic diagram of the structure is that the bottle presser assembly of the automatic sampler is in the second position and the injection needle extends into the injection bottle for injection.

[0049] Fig.23 Shown Figure 1 A schematic cross-sectional view of a sample container of an autosampler is shown. DETAILED DESCRIPTION

[0050] Exemplary embodiments will be described in detail herein, examples of which are shown in the accompanying drawings. When the following description refers to the drawings, the same numbers in different drawings represent the same or similar elements unless otherwise indicated. The implementations described in the following exemplary embodiments do not represent all implementations consistent with the present application. Instead, they are merely examples of devices and methods consistent with some aspects of the present application as detailed in the appended claims.

[0051] The terms used in this application are only for the purpose of describing specific embodiments and are not intended to limit this application. Unless otherwise defined, the technical terms or scientific terms used in this application should be understood by people with ordinary skills in the field to which the present invention belongs. The words "first", "second" and similar words used in the specification and claims of this application do not indicate any order, quantity or importance, but are only used to distinguish different components. Similarly, words such as "one" or "one" do not indicate a quantity limit, but indicate that there is at least one. "Multiple" or "several" means at least two. Unless otherwise specified, words such as "front", "rear", "lower" and / or "upper" are only for convenience of explanation and are not limited to one position or one spatial orientation. Words such as "include" or "comprise" mean that the elements or objects appearing in front of "include" or "comprise" include the elements or objects listed after "include" or "comprise" and their equivalents, and do not exclude other elements or objects. Words such as "connect" or "connected" are not limited to physical or mechanical connections, and can include electrical connections, whether direct or indirect.

[0052] The singular forms "a", "said" and "the" used in this specification and the appended claims are also intended to include the plural forms, unless the context clearly indicates otherwise. It should also be understood that the term "and / or" used herein refers to and includes any or all possible combinations of one or more of the associated listed items.

[0053] The present application provides an automatic sampler, comprising at least two brackets arranged opposite to each other, a first transmission shaft, a fixed bracket, a sample injection needle, a sample container, a bottle presser assembly and a first driving mechanism. At least two brackets arranged opposite to each other, the brackets are extended up and down. The first transmission shaft is arranged between the at least two brackets. The fixed bracket is movably connected to the first transmission shaft. The sample injection needle is fixed to the fixed bracket. The sample container is arranged below the fixed bracket. The bottle press assembly is connected to the fixed bracket and can move up and down relative to the first transmission shaft. The bottle press assembly can be located in a first position or a second position. In the first position, the bottle press assembly is separated from the sample container, and in the second position, the bottle press assembly is pressed against the top surface of the sample container; the first driving mechanism is arranged on the bracket and connected to the first transmission shaft; the first driving mechanism is used to drive the first transmission shaft to rotate, drive the fixed bracket and the bottle press assembly to move up and down, and move the bottle press assembly between the first position and the second position; and when the bottle press assembly is in the second position, the first transmission shaft is driven to rotate, drive the fixed bracket to move up and down relative to the bottle press assembly, and the injection needle is inserted into or pulled out of the sample container.

[0054] In the automatic sampler of the embodiment of the present application, the bottle presser assembly is connected to the fixed bracket, and the first driving mechanism drives the first transmission shaft to rotate, driving the fixed bracket and the bottle presser assembly to move up and down together; when the bottle presser assembly is in the second position, the first driving mechanism drives the first transmission shaft to rotate, driving the fixed bracket to move up and down relative to the bottle presser assembly, so that the injection needle can be inserted into or pulled out of the sample container. In this arrangement, the same first driving mechanism is used to drive the first rotating shaft to rotate, driving the fixed bracket to move up and down, and driving the bottle presser assembly to move up and down, which meets the functional requirements, reduces the number of driving mechanisms and transmission mechanisms, and reduces costs.

[0055] The present application provides an automatic sample injector. The automatic sample injector of the present application is described in detail below in conjunction with the accompanying drawings. In the absence of conflict, the features of the following embodiments and implementations can be combined with each other.

[0056] Figure 1 FIG. 1 is a schematic diagram of the structure of an embodiment of the automatic sample injector 10 of the present application. Figure 1As shown, the automatic sampler 10 includes a chassis 101, at least two relatively arranged brackets 102, a connecting shaft assembly 103, a driving mechanism 104, a transmission mechanism 105, a fixed bracket 106, a bottle press assembly 107 and a sample container. The sample container is arranged below the fixed bracket 106. The sample container includes a sample injection bottle 108 and a sample suction bottle (not shown). At least two relatively arranged brackets 102 and the sample injection bottle 108 are both arranged on the chassis 101. The connecting shaft assembly 103 is connected between at least two relatively arranged brackets 102. The driving mechanism 104 is arranged on the bracket 102 and is transmission-connected to the transmission mechanism 105. The transmission mechanism 105 is movably connected to the connecting shaft assembly 103. The sample injection bottle 108 is located below the transmission mechanism 105.

[0057] In some embodiments, the bracket 102 is extended up and down. In this embodiment, the bracket 102 includes a first bracket 109 and a second bracket 110, and the first bracket 109 and the second bracket 110 are arranged opposite to each other and are both extended up and down. The connecting shaft assembly 103 includes a first transmission shaft 111, a plurality of second transmission shafts 112, and a third transmission shaft 113. The first transmission shaft 111, a plurality of second transmission shafts 112, and the third transmission shaft 113 are arranged between at least two brackets 102. In this embodiment, the first transmission shaft 111, a plurality of second transmission shafts 112, and the third transmission shaft 113 are all extended horizontally and arranged in parallel between the first bracket 109 and the second bracket 110. The first transmission shaft 111, a plurality of second transmission shafts 112, and the third transmission shaft 113 are all extended horizontally and arranged in parallel between the first bracket 109 and the second bracket 110. In the extension direction of the bracket 102, the first transmission shaft 111 is located above the second transmission shaft 112. The third transmission shaft 113 is located between the two second transmission shafts 112. The first transmission shaft 111 and the third transmission shaft 113 can be movably connected relative to the bracket 102, and the second transmission shaft 112 is fixedly connected relative to the bracket 102. In this embodiment, the first transmission shaft 111 can be a spline shaft. The second transmission shaft 112 can be an optical axis, which refers to a smooth transmission shaft. The third transmission shaft 113 can be a lead screw.

[0058] In this embodiment, the automatic sampler 10 further includes a sample tray assembly 114 and a sample injection needle. The sample tray assembly 114 accommodates the sample suction bottle. The sample injection needle is connected to the transmission mechanism 105. The sample injection needle is fixed to the fixed bracket 106. The fixed bracket 106 is used to fix the sample injection needle, and the fixed bracket 106 is fixed to the transmission mechanism 105 and is movably connected to the first transmission shaft 111. The driving mechanism 104 includes a first driving mechanism 135, a second driving mechanism 133 and a third driving mechanism 134. The first driving mechanism 135 and the third driving mechanism 134 are arranged on the bracket 102, for example, on the first bracket 109 or the second bracket 110. The second driving mechanism 133 is arranged on the chassis 101. The first transmission shaft 111, a plurality of second transmission shafts 112, and a third transmission shaft 113 are arranged in parallel between at least two brackets 102. The sample tray assembly 114 is arranged on the chassis 101. The second driving mechanism 133 drives the sample tray assembly 114 to do circular motion. The third driving mechanism 134 is connected to the third transmission shaft 113 by transmission, and the third driving mechanism 134 drives the third transmission shaft 113 to rotate, driving the transmission mechanism 105 to do horizontal movement, thereby driving the injection needle to do horizontal movement. In the process of doing horizontal movement, the multiple second transmission shafts 112 play a restraining role to ensure the horizontal movement of the transmission mechanism 105. The injection needle is connected to the transmission mechanism 105 through the fixed bracket 106, and the driving mechanism 104 is connected to the transmission mechanism 105, and the driving mechanism 104 drives the transmission mechanism 105 to move axially along the multiple second transmission shafts 112, driving the injection needle to move axially along the multiple second transmission shafts 112. The first driving mechanism 135 is connected to the first transmission shaft 111 by transmission, and the first driving mechanism 135 drives the first transmission shaft 111 to rotate, driving the fixed bracket 106 to do up and down movement, thereby driving the injection needle to do up and down movement.

[0059] Figure 2 Shown is a schematic structural diagram of a front view of a fixing bracket 106 of the injection needle of the present application. Figure 3 Shown Figure 2 The structure diagram of the fixing bracket 106 of the injection needle shown is a rear view perspective. Figure 4 Shown Figure 2 A schematic side cross-sectional view of a fixing bracket 106 for an injection needle is shown. Figure 5 Shown Figure 2 The bottom view of the fixed bracket 106 of the injection needle is shown.

[0060] like Figures 2 to 5As shown, the fixed bracket 106 is used for the automatic sample injector 10, and is used to fix the injection needle. The fixed bracket 106 includes a bracket body 115 and an elastic component 116. The fixed bracket 106 is an integrated structure. In the present embodiment, the bracket body 115 is an integrated structure. The bracket body 115 includes a locking needle groove 117, and the locking needle groove 117 accommodates the injection needle. The elastic component 116 is fixedly connected to the locking needle groove 117, and the elastic component 116 clamps the injection needle so that the injection needle is fixed in the locking needle groove 117, and can be elastically deformed relative to the locking needle groove 117 to allow the injection needle to be inserted or pulled out. During use, the injection needle is inserted into the locking needle groove 117 from bottom to top and locked by the elastic component 116. After use, the injection needle is pulled out from the locking needle groove 117 from top to bottom. The present application utilizes the locking needle groove 117 of the bracket body 115 to accommodate the injection needle, and utilizes the elastic component 116 to clamp the injection needle, so that the injection needle is fixed in the locking needle groove 117, and can be elastically deformed relative to the locking needle groove 117 to allow the injection needle to be inserted or pulled out. Compared with the related art, the elastic component 116 is deformed during the insertion or removal of the injection needle, and the elastic component 116 automatically recovers after the insertion or removal. This installation method does not need to consider the loosening of parts such as bolts, is not easy to loosen, can achieve a stable connection of the injection needle, is stable and reliable, and has a simple structure and installation method.

[0061] In some embodiments, the elastic component 116 is integrally formed with the bracket body 115. The elastic component 116 is integrally formed with the bracket body 115, and the mold is split once, which is convenient to install and has a simple structure and low cost. In some embodiments, the elastic component 116 includes an elastic paddle extending up and down. The elastic paddle is easy to deform and is in surface contact with the injection needle, so the fixing effect is more stable and not easy to loosen.

[0062] Figure 6 The schematic diagram is a front view of the structure of the injection needle 118 of the present application being inserted into the fixing bracket 106 . Figure 7 Shown Figure 6 The injection needle 118 is shown as a schematic cross-sectional side view of the mounting bracket 106 . Figure 8 Shown Figure 6 The cross-sectional view of the injection needle 118 shown is inserted into the bottom view of the fixed bracket 106. Figures 2 to 8 As shown, the injection needle 118 is inserted into the fixing bracket 106, and the elastic component 116 clamps the injection needle 118 so that the injection needle 118 is fixed in the locking needle groove 117. The injection needle 118 includes a needle body 119 and a needle fixing portion 120 connected to the needle body 119, and the needle fixing portion 120 protrudes radially outward relative to the needle body 119. The needle fixing portion 120 is used to fix the needle body 119. Figure 6 , Figure 7 and Fig. 9In the illustrated embodiment, the elastic component 116 is clamped on the side of the needle fixing portion 120 of the injection needle 118 so that the needle fixing portion 120 is locked in the needle locking groove 117 .

[0063] The elastic component 116 includes a connecting portion 121 and an elastic portion 122 connected to the lower end of the connecting portion 121. The connecting portion 121 is fixedly connected to the locking needle groove 117. There is a gap extending up and down between the elastic portion 122 and the locking needle groove 117, and the elastic portion 122 can be elastically deformed relative to the locking needle groove 117. In this arrangement, the connecting portion 121 is used to abut against the needle fixing portion 120 of the injection needle 118, and the elastic portion 122 is deformed, which facilitates the insertion of the needle fixing portion 120 of the injection needle 118 into the locking needle groove 117 or the extraction of the needle fixing portion 120 from the locking needle groove 117. This installation method is simple.

[0064] In some embodiments, the number of elastic components 116 is set to be multiple, and the multiple elastic components 116 are together around the outside of the injection needle and elastically clamp the injection needle, and there is a gap extending up and down between the elastic parts 122 of the multiple elastic components 116. In this embodiment, the multiple elastic components 116 are together around the outside of the needle fixing part 120 of the injection needle 118 and elastically clamp the needle fixing part 120 of the injection needle 118, and there is a gap extending up and down between the elastic parts 122 of the multiple elastic components 116. This arrangement allows sufficient space between the elastic parts 122 of the multiple elastic components 116 to accommodate the needle fixing part 120 and have space for deformation, so that the needle fixing part 120 of the injection needle 118 can be inserted into or pulled out of the locking needle groove 117. This installation method is simple and has a simple structure. In this embodiment, there are also gaps extending up and down between the connecting parts 121 of the multiple elastic components 116, so that the connecting parts 121 of the multiple elastic components 116 apply force on different sides of the needle fixing part 120 of the injection needle 118 to clamp the needle fixing part 120 of the injection needle 118, which has better stability.

[0065] In some embodiments, the bracket body 115 includes a stopper 123 convexly arranged on the upper edge of the locking needle groove 117. The stopper 123 is located above the connecting portion 121 and blocks the injection needle 118 downward. In this embodiment, the stopper 123 blocks the needle fixing portion 120 of the injection needle 118 downward. Since the injection needle 118 is subjected to force from bottom to top, the stopper 123 on the upper edge of the locking needle groove 117 can prevent the needle fixing portion 120 from moving upward, and prevent the needle fixing portion 120 from detaching from the locking needle groove 117. The structure is simple, stable and reliable. In some embodiments, the elastic portion 122 includes an elastic side wall 124 and an elastic protrusion 125 convexly arranged on the elastic side wall 124. The locking needle groove 117 accommodates the needle fixing portion 120. The elastic protrusion 125 supports the bottom surface of the needle fixing portion 120 upward, and the stopper 123 blocks the top surface of the needle fixing portion 120 downward. With such arrangement, the needle fixing portion 120 is resisted downward by the stopper 123 and supported upward by the elastic protrusion 125, so that the needle fixing portion 120 is stably fixed in the needle locking groove 117, making it difficult for the needle fixing portion 120 to move upward or slide downward, being stable and reliable, having a simple structure and low cost.

[0066] In this embodiment, the needle body 119 includes a first needle segment 126 connected to the lower end of the needle fixing portion 120 and a second needle segment 127 connected to the upper end of the needle fixing portion 120. In some embodiments, the stopper 123 includes a first stopper 128 and a second stopper 129 (such as Figure 2 or Figure 6 As shown in FIG. 1 , there is a gap between the first stopper 128 and the second stopper 129, and the first stopper 128 and the second stopper 129 push downward against the top surface of the needle fixing part 120, and the gap between the first stopper 128 and the second stopper 129 accommodates at least a portion of the second needle segment 127. In this way, the needle fixing part 120 is pushed into the locking needle groove 117 by the first stopper 128 and the second stopper 129, and the first needle segment 126 extends from the gap between the first stopper 128 and the second stopper 129 to the outside of the locking needle groove 117, so that the fixing method of the needle body 119 of the injection needle 118 and the needle fixing part 120 is not easy to loosen, is stable and reliable, and has a simple structure.

[0067] Fig. 9 Shown Figure 6 The fixing bracket 106 of the injection needle is shown to be fixed to the transmission mechanism 105 in a sectional schematic view from a side view. Fig.10 Shown Figure 6 The fixed bracket 106 of the injection needle shown is fixed to the bottom view of the transmission mechanism 105. Figures 1 to 10As shown, in some embodiments, the locking needle groove 117 can be a through groove that runs through in the front-to-back direction, or a groove with a groove bottom. In this embodiment, the locking needle groove 117 is a through groove that runs through in the front-to-back direction. In some embodiments, the plurality of elastic components 116 include a first elastic component 130 disposed in the locking needle groove 117, and at least one second elastic component 131 protruding from the locking needle groove 117. In this embodiment, three elastic components 116 are provided, one of which is the first elastic component 130, which is disposed in the locking needle groove 117, and the other two are the second elastic components 131, which are protruding from the locking needle groove 117. The two second elastic components 131 and the first elastic component 130 enclose concentric circles to press the needle fixing portion 120 together, and the structure is simple, stable and reliable. In some embodiments, the first elastic component 130 includes an elastic portion 122, and an anti-loosening boss 132 is provided on the side of the elastic portion 122 of the first elastic component 130 facing away from the injection needle 118, and the anti-loosening boss 132 is located at the bottom of the elastic portion 122. When the fixed bracket 106 is fixed to the transmission mechanism 105, the anti-loosening boss 132 is squeezed by the transmission mechanism 105, so that the elastic portion 122 presses against the side of the injection needle. In this embodiment, an anti-loosening boss 132 is provided on the side of the elastic portion 122 of the first elastic component 130 facing away from the needle fixing portion 120 of the injection needle 118. The anti-loosening boss 132 is protruding from the surface of the first elastic component 130. When the fixing bracket 106 is fixed to the transmission mechanism 105, the anti-loosening boss 132 abuts against the transmission mechanism 105 and squeezes the elastic portion 122 to cause the elastic portion 122 to contract, fitting more closely to the side of the needle fixing portion 120 of the injection needle 118, making it less likely to loosen and more stable and reliable.

[0068] Fig.11 Shown Figure 1 A partial structural schematic diagram of the automatic sample injector 10 is shown in the front view. Fig.12 Shown Figure 1 The schematic diagram of the partial structure of the automatic sample injector 10 shown in the rear view angle. Figures 1 to 12 As shown, the transmission mechanism 105 is movably connected to the plurality of second transmission shafts 112. During the horizontal movement, the plurality of second transmission shafts 112 play a restraining role. Since the first transmission shaft 111, the plurality of second transmission shafts 112, and the third transmission shaft 113 are arranged in parallel and jointly restrain the horizontal sliding of the transmission mechanism 105, any relative position deviation will cause the transmission mechanism 105 to get stuck during the movement.

[0069] To avoid this problem, in the present application, the bracket 102 is provided with a plurality of mounting holes 136. A plurality of second transmission shafts 112 are arranged in parallel between at least two brackets 102, and both ends of the plurality of second transmission shafts 112 are inserted into the corresponding mounting holes 136 and are loosely matched with the mounting holes 136. The automatic sampler 10 also includes a plurality of optical axis fixing members 137, and the plurality of optical axis fixing members 137 are respectively arranged at both ends of the plurality of second transmission shafts 112. The optical axis fixing member 137 is fixedly connected to the bracket 102, and is clamped at the end of the second transmission shaft 112, and the second transmission shaft 112 is limited in the axial direction of the second transmission shaft 112, and is loosely matched with the second transmission shaft 112 in the radial direction of the second transmission shaft 112.

[0070] In this embodiment, a plurality of second transmission shafts 112 are horizontally extended, and the first bracket 109 and the second bracket 110 are both extended up and down, and both are provided with mounting holes 136. The two ends of the plurality of second transmission shafts 112 are respectively inserted into the mounting holes 136 corresponding to the first bracket 109 and the second bracket 110, and are clearance-matched with the mounting holes 136. The clearance-matching refers to the shaft-hole matching, and the maximum size of the mounting hole 136 is greater than the maximum size of the second transmission shaft 112. At the same time, a plurality of optical axis fixing members 137 provided at the two ends of the plurality of second transmission shafts 112 are clamped on the ends of the second transmission shaft 112, and the second transmission shaft 112 is limited in the axial direction of the second transmission shaft 112, and is clearance-matched with the second transmission shaft 112 in the radial direction of the second transmission shaft 112, so as to realize the floating connection between the second transmission shaft 112 and the bracket (the first bracket 109 and the second bracket 110), which can be compatible with the processing error of the optical axis, is not easy to cause motion stagnation, improves the motion reliability, and the floating connection is fast and easy to install. In the above scheme, the optical axis fixing part 137 is mainly used to constrain the horizontal position of the second transmission shaft 112 from moving. A certain gap is left in the radial direction (circumferential side) of the second transmission shaft 112 to compensate for processing and assembly errors, thereby avoiding the problem of the transmission mechanism 105 getting stuck with the second transmission shaft 112 during horizontal movement due to the non-parallelism between the multiple second transmission shafts 112, and is stable and reliable.

[0071] In some embodiments, the optical axis fixing member 137 includes a first optical axis fixing member 138 and a second optical axis fixing member 144 . Fig.13 The exploded view is shown in which the first optical axis fixing member 138 of the automatic sample injector 10 of the present application is not assembled to the bracket 102 . Fig.14 Shown Fig.13 The structure diagram of the first optical axis fixing member 138 of the automatic sample injector 10 is shown in a side view without assembling the bracket 102 . Fig.15 Shown Fig.13 The structure diagram shown is that the first optical axis fixing member 138 of the automatic sample injector 10 is assembled to the bracket 102. Fig.16The exploded view is shown in which the second optical axis fixing member 144 of the automatic sample injector 10 of the present application is not assembled to the bracket 102 . Fig.17 Shown Fig.16 The structure diagram of the second optical axis fixing member 144 of the automatic sample injector 10 is shown in a side view without assembling the bracket 102 . Fig.18 Shown Fig.16 The second optical axis fixing member 144 of the automatic sample injector 10 is assembled to the bracket 102. Figures 13 to 15 The optical axis fixing member 137 of the embodiment shown is a first optical axis fixing member 138. Figures 16 to 18 The optical axis fixing member 137 of the illustrated embodiment is a second optical axis fixing member 144 .

[0072] Combination Figures 11 to 15 As shown, the optical axis fixing member 137 includes a clamping portion 139 and a fixing portion 140 connected to the clamping portion 139, the fixing portion 140 is fixedly connected to the bracket 102, a limiting groove 141 is provided on the circumference of the end of the second transmission shaft 112, the clamping portion 139 is clamped in the limiting groove 141, and cooperates with the limiting groove 141 in the axial upper limit of the second transmission shaft 112, and has a radial gap between the limiting groove 141 and the radial direction of the second transmission shaft 112. In this embodiment, the axial direction of the second transmission shaft 112 is a horizontal direction, and the radial direction of the second transmission shaft 112 refers to a direction perpendicular to the axial direction of the second transmission shaft 112. Since the two ends of the plurality of second transmission shafts 112 are respectively inserted into the corresponding mounting holes 136 of the bracket 102, and are floatingly connected with the mounting holes 136. There is a gap between the second transmission shaft 112 and the mounting hole 136. Therefore, the optical axis fixing part 137 is used to fix on the bracket 102 to ensure that the horizontal position of the second transmission shaft 112 does not move, and the radial gap between the clamping part 139 and the limiting groove 141 is used to ensure that there is a movable gap between the clamping part 139 and the limiting groove 141, so as to achieve the effect of compensating for processing and assembly errors, and avoid the problem of the transmission mechanism 105 getting stuck with the second transmission shaft 112 during horizontal movement due to the non-parallelism between the multiple second transmission shafts 112, which is stable and reliable.

[0073] In some embodiments, the size of the radial gap ranges from 0.1 mm to 0.7 mm. In some embodiments, the size of the radial gap is 0.1 mm or 0.2 mm or 0.3 mm or 0.4 mm or 0.5 mm or 0.6 mm or 0.7 mm. Fig.15In the embodiment shown, the radius R1 of the limiting groove 141 of the second transmission shaft 112 is preferably 3 mm, and the radius R2 of the semi-arc limiting notch 142 is preferably 3.4 mm. The preferred value of the radial clearance is 0.4 mm. The radial clearance between the clamping portion 139 and the limiting groove 141 in the radial direction of the second transmission shaft 112 is appropriately set to avoid the problem of motion jamming caused by poor part processing. In addition, the processing deviation can be compensated, and a precise and stable connection can be achieved, thereby improving the stability of the movement.

[0074] In some embodiments, the clamping portion 139 is provided with a limiting notch 142, and the limiting notch 142 and the limiting groove 141 are clearance matched in the radial direction of the second transmission shaft 112. Such a configuration ensures that the clamping portion 139 can achieve the fixation of the position of the adaptive second transmission shaft 112 through the limiting notch 142 and the limiting groove 141, which is stable and reliable. In some embodiments, the limiting notch 142 is semi-arc-shaped and extends in an arc shape in the extension direction from the upper side to the lower side of the second transmission shaft 112. In this embodiment, the extension direction from the upper side to the lower side of the second transmission shaft 112 can also be the upper and lower extension direction of the bracket 102. In the radial direction of the second transmission shaft 112, it is clearance matched with the limiting groove 141.

[0075] In some embodiments, the clamping portion 139 and the limiting groove 141 have an axial gap in the axial direction of the second transmission shaft 112. In some embodiments, the size of the axial gap ranges from 0.02 mm to 0.08 mm. In some embodiments, the size of the axial gap is 0.02 mm or 0.03 mm or 0.04 mm or 0.05 mm or 0.06 mm or 0.07 mm or 0.08 mm. Fig.18 In the illustrated embodiment, the dimension L1 of the clamping portion 139 in the axial direction of the second transmission shaft 112 is preferably 1.6 mm, and the dimension L2 of the limiting groove 141 in the axial direction of the second transmission shaft 112 is preferably 1.65 mm. The preferred value of the axial clearance is 0.05 mm. The axial clearance between the clamping portion 139 and the limiting groove 141 in the axial direction of the second transmission shaft 112 is appropriately set to avoid the problem of motion jamming caused by poor part processing. In addition, the processing deviation can be compensated, and a precise and stable connection can be achieved, thereby improving the stability of the movement.

[0076] In some embodiments, the bracket 102 is extended up and down. The inner side of the bracket 102 is provided with a snap-in groove 143, and the snap-in portion 139 is snap-into the snap-in groove 143. In the direction of the bracket 102 extending up and down, there is a gap between the snap-in portion 139 and the snap-in groove 143. In some embodiments, the first bracket 109 and the second bracket 110 are extended up and down. The first bracket 109 and the second bracket 110 are provided with a snap-in groove 143, and the snap-in groove 143 of the first bracket 109 is arranged opposite to the snap-in groove 143 of the second bracket 110. Fig.14 or Fig.17In the embodiment shown, the preferred size L3 of the clamping portion 139 is 12 mm, and the preferred size L4 of the clamping slot 143 is 12.1 mm. A suitable gap is provided between the clamping portion 139 and the clamping slot 143 to facilitate the clamping portion 139 to be inserted into the clamping slot 143.

[0077] exist Figures 13 to 15 In the illustrated embodiment, the fixing portion 140 of the first optical axis fixing member 138 is bent relative to the clamping portion 139, and the clamping portion 139 of the first optical axis fixing member 138 is arranged on the inner side surface of the bracket 102, and the fixing portion 140 of the first optical axis fixing member 138 is arranged on the adjacent side surface of the inner side surface of the bracket 102. Since the length of the second transmission shaft 112 has a deviation, the fixing position of the first optical axis fixing member 138 needs a certain amount of adjustment. Therefore, the clamping portion 139 of the first optical axis fixing member 138 is arranged on the inner side surface of the bracket 102, and the fixing portion 140 is arranged on the adjacent side surface of the inner side surface of the bracket 102, and the radial clearance between the clamping portion 139 and the limiting groove 141 in the radial direction of the second transmission shaft 112 is used to achieve the fixing of the adaptive optical axis position, which is stable and reliable. In some embodiments, the first optical axis fixing members 138 are respectively arranged at both ends of the same second transmission shaft 112. In this way, the dimensional deviation of the two ends of the same second transmission shaft 112 can be adjusted.

[0078] exist Figures 16 to 18 In the illustrated embodiment, the difference between the second optical axis fixing member 144 and the first optical axis fixing member 138 is that the fixing portion 140 and the clamping portion 139 of the second optical axis fixing member 144 are both arranged on the inner side of the bracket 102. The second optical axis fixing member 144 is fixed to the inner side of the bracket 102 by the self-positioning function of the countersunk screw, so as to play the role of positioning the optical axis 12, and there is no redundant adjustment amount. Therefore, the second optical axis fixing member 144 is used in conjunction with the first optical axis fixing member 138. In this embodiment, the first optical axis fixing member 138 is arranged at one end of the second transmission shaft 112, and the second optical axis fixing member 144 is arranged at the other end of the second transmission shaft 112. In this arrangement, while ensuring that one end of the second transmission shaft 112 is fixed, the other end can be adjusted, which can compensate for processing and assembly errors, and avoid the problem of the transmission mechanism 105 being stuck with the second transmission shaft 112 during horizontal movement due to the non-parallelism between the multiple second transmission shafts 112, which is stable and reliable.

[0079] It should be noted that the working process of the automatic sampler 10 includes sample suction, injection, needle washing, re-sampling, and re-injection. The specific operation sequence can be set by software / hardware. For example, a computer (PC) is used to send instructions and parameters (setting parameters such as sample installation quantity, position number, sample amount, injection speed, etc.) to a controller (PLC), and the controller generates corresponding signals to control the drive mechanism 104 (the first drive mechanism 135, the second drive mechanism 133, and the third drive mechanism 134) respectively, and the drive transmission mechanism 105 drives the fixed bracket 106 to move horizontally or up and down.

[0080] Combination Figure 1 and 19 As shown, the bottle pressing assembly 107 is connected to the fixed bracket 106 and can move up and down relative to the first transmission shaft 111. The bottle pressing assembly 107 can be located in the first position or the second position. Figure 20 to Figure 21 As shown, in Fig. 20 In the illustrated embodiment, the bottle press assembly 107 is in a first position. In the first position, the bottle press assembly 107 is in contact with the sample container (eg, Fig. 20 and 21 The sample injection bottle 108 shown is separated. Fig.21 In the embodiment shown, when the bottle press assembly 107 is in the second position, the bottle press assembly 107 presses against the sample container (such as Fig. 20 and Fig. 22 The top surface of the sample injection bottle 108 is shown.

[0081] Combination Figure 1 , Figures 19 to 22 As shown, the first driving mechanism 135 is connected to the first transmission shaft 111. The first driving mechanism 135 is used to drive the first transmission shaft 111 to rotate, drive the fixed bracket 106 and the bottle press assembly 107 to move up and down, and make the bottle press assembly 107 move between the first position and the second position. When the bottle press assembly 107 is between the first position and the second position, the first driving mechanism 135 is used to drive the first transmission shaft 111 to rotate, drive the fixed bracket 106 and the bottle press assembly 107 to move up and down together (such as Figure 20 to Figure 21 When the bottle press assembly 107 is in the second position, the first driving mechanism 135 is used to drive the first transmission shaft 111 to rotate, driving the fixed bracket 106 to move up and down relative to the bottle press assembly 107, so that the injection needle is inserted into or pulled out of the sample container (such as Fig. 22 shown).

[0082] exist Figure 20 to Figure 22 In the embodiment shown, when the automatic sampler 10 is sucking or injecting a sample, the first driving mechanism 135 drives the first transmission shaft 111 to rotate, driving the fixed bracket 106 and the bottle pressing assembly 107 to move downward synchronously, so that the bottle pressing assembly 107 moves from the first position (such as Fig.21 ) to the second position (as shown) Fig. 22 When the bottle press assembly 107 is in the second position, the first drive mechanism 135 drives the first transmission shaft 111 to rotate, driving the fixed bracket 106 to continue to move downward relative to the bottle press assembly 107, so that the injection needle is inserted into or removed from the sample container. Figure 20 to Figure 22 In the illustrated embodiment, the sample container comprises a sample injection bottle 108. In other embodiments, the sample container comprises a sample suction bottle. When the bottle presser assembly 107 is in the second position, the sample injection needle extends into the sample suction bottle to suction the sample.

[0083] In the above scheme, the same first driving mechanism 135 is used to drive the first rotating shaft 111 to rotate, so that the fixed bracket 106 and the bottle press assembly 107 can move up and down to complete sample suction or injection, meet functional requirements, reduce the number of transmission mechanisms 105, and reduce costs.

[0084] exist Figures 19 to 22 In the illustrated embodiment, the bottle pressing assembly 107 includes a bottle pressing member 145, a positioning shaft 146, and a first elastic member 147. The positioning shaft 146 extends up and down, the bottle pressing member 145 is disposed at the bottom of the positioning shaft 146, the first elastic member 147 is sleeved on the positioning shaft 146, and the fixing bracket 106 is disposed on the top of the first elastic member 147 and connected to the positioning shaft 146. Fig. 20 In the illustrated embodiment, when the bottle pressing assembly 107 is in the first position, the bottle pressing member 145 is separated from the sample container, the fixed bracket 106, the top of the first elastic member 147 and the top of the positioning shaft 146 are connected, and the first driving mechanism 135 is used to drive the first transmission shaft 111 to rotate, driving the fixed bracket 106, the bottle pressing member 145, the positioning shaft 146 and the first elastic member 147 to move up and down together. Fig.21 In the illustrated embodiment, when the bottle pressing assembly 107 is in the second position, the bottle pressing member 145 presses against the top surface of the sample container, and the first driving mechanism 135 is used to drive the first transmission shaft 111 to rotate, driving the fixed bracket 106 to move up and down relative to the positioning shaft 146. The tops of the fixed bracket 106 and the first elastic member 147 are separated from the top of the positioning shaft 146, and the first elastic member 147 is elastically deformed up and down to interact with the fixed bracket 106. In this way, the fixed bracket 106 is connected to the first elastic member 147, and is used in conjunction with the bottle pressing member 145 and the positioning shaft 146. The first driving mechanism 135 drives the first transmission shaft 111 to rotate, driving the fixed bracket 106 to move up and down, and driving the bottle pressing assembly 107 to move up and down. In this way, the driving mechanism and transmission mechanism for driving the bottle pressing assembly 107 can be reduced, and the structure is simple, the transmission method is simple, and the cost is low.

[0085] exist Figures 19 to 22In the illustrated embodiment, the bottle pressing assembly 107 further includes a grating 148 and a light triggering member 149. The grating 148 is fixedly disposed on the top of the positioning shaft 146, and the light triggering member 149 is disposed on the top of the first elastic member 147 and is fixedly connected to the fixing bracket 106 and the top of the first elastic member 147. Fig. 20 In the illustrated embodiment, when the bottle pressing assembly 107 is in the first position, the optical trigger 149 is connected to the grating 148, the fixed bracket 106, the top of the first elastic member 147 and the top of the positioning shaft 146 are connected, and the first driving mechanism 135 is used to drive the first transmission shaft 111 to rotate, driving the fixed bracket 106, the optical trigger 149 and the grating 148 to move up and down together. Fig.21 and Fig. 22 In the illustrated embodiment, when the bottle pressing assembly 107 is in the second position, the first driving mechanism 135 is used to drive the first transmission shaft 111 to rotate, driving the fixed bracket 106 and the light trigger 149 to move up and down relative to the grating 148, and the light trigger 149 is separated from the grating 148. The grating 148 is used to detect the movement distance of the fixed bracket 106 relative to the positioning shaft 146 to detect the movement distance of the injection needle. In some embodiments, the grating 148 can be a transceiver type sensor. In some embodiments, the grating 148 includes a light transmitter and a light receiver, and the light transmitter is used to transmit a light signal to the light trigger 149, and the light signal received by the light receiver is used to obtain the relative position between the light trigger 149 and the grating 148, so as to obtain the movement distance of the fixed bracket 106 relative to the positioning shaft 146, thereby detecting the movement distance of the injection needle into the sample container. In this way, the relative position between the light trigger 149 and the grating 148 can be detected, so as to determine whether the injection needle is stuck according to the relative position, and avoid abnormal phenomena. It can also facilitate the detection of the movement distance of the injection needle into the sample container, ensuring smooth completion of injection or aspiration and improving efficiency.

[0086] exist Figures 19 to 22 In the illustrated embodiment, the bottle pressing assembly 107 further includes a first fixing member 150, which is disposed on the top of the first elastic member 147 and is fixedly connected to the fixing bracket 106. The optical triggering member 149 is fixed to the first fixing member 150. The first fixing member 150 supports the optical triggering member 149 to avoid the problem of inaccurate detection data due to the optical triggering member 149 being misaligned during the movement of the positioning shaft 146.

[0087] exist Figures 19 to 22In the illustrated embodiment, the fixed bracket 106 includes a bracket slot 151 extending upward and downward, the first fixing member 150 is provided with a through hole 152 extending upward and downward, the positioning shaft 146 is penetrated in the through hole 152, the top of the bracket slot 151 is pressed against the top surface of the first fixing member 150, the bottom surface of the first fixing member 150 is pressed against the top of the first elastic member 147, and the side surface of the first fixing member 150 is engaged with the side wall of the bracket slot 151. When the bottle press assembly 107 is in the second position, the first driving mechanism 135 is used to drive the first transmission shaft 111 to rotate, driving the fixed bracket 106 and the first fixing member 150 to move up and down together relative to the positioning shaft 146. Such a configuration ensures that when the first driving mechanism 135 drives the first transmission shaft 111 to rotate and drives the fixed bracket 106 to move up and down, it can drive the bottle press assembly 107 to move up and down. The connecting component between the first transmission shaft 111 and the bottle pressing assembly 107 can be omitted, and the driving mechanism for driving the bottle pressing assembly 107 can also be omitted, which has a simple structure and low cost. In addition, the fixed bracket 106 is an integrated structure, which is linked to the bottle pressing assembly 107, has a small number of components, and is easy to assemble.

[0088] exist Figures 19 to 22 In the illustrated embodiment, the bottle pressing assembly 107 further includes a second fixing member 153, which is fixed to the top of the positioning shaft 146, and the grating 148 is disposed on the second fixing member 153. The second fixing member 153 serves to fix the grating 148, thereby preventing the grating 148 from being misaligned during the movement of the positioning shaft 146, thereby preventing the problem of inaccurate detection data.

[0089] Combination Figure 1 , Figure 20 to Figure 23 As shown, the injection bottle 108 is arranged below the bottle pressing assembly 107. The injection bottle 108 includes an outer shell 154, a bottle cap 155 covered on the outer shell 154, and an injection seat 156 arranged in the outer shell 154. When the bottle pressing assembly 107 is in the second position, the bottle pressing member 145 presses against the top surface of the bottle cap 155, and the first driving mechanism 135 is used to drive the first transmission shaft 111 to rotate, drive the fixed bracket 106 to press the first elastic member 147 to move up and down relative to the positioning shaft 146, and drive the injection needle to move up and down relative to the bottle cap 155, and insert or pull out the injection seat 156.

[0090] Combination Figure 1 , Figure 20 to Figure 23As shown, the injection bottle 108 also includes a second elastic member 157 and a pressure sensor 158 disposed in the outer shell 154. The pressure sensor 158 is disposed at the bottom of the outer shell 154, and the pressure sensor 158 is elastically connected to the injection seat 156 through the second elastic member 157; when the bottle pressing assembly 107 is in the second position, the bottle pressing member 145 presses against the top surface of the bottle cap 155, and when the injection needle moves downward relative to the bottle cap 155 and inserts into the injection seat 156, the pressure sensor 158 is used to detect the pressure of the injection needle on the injection seat 156, and the controller is used to control the first driving mechanism 135 to stop driving the first transmission shaft 111 to rotate when the pressure sensor 158 detects that the pressure reaches the pressure threshold. With the increase in the demand for ultra-high efficiency chromatographs, the injection efficiency, pressure resistance and cost of the automatic sampler 10 have higher requirements. For example, the liquid pressure of the ultra-high performance chromatograph exceeds 100Mpa, and the injection needle and the injection seat 156 elastically seal this pressure through contact. Since 100Mpa is close to the compressive strength of the needle seat material, more precise requirements are put forward for the positive pressure of the injection needle and the injection seat 156. Therefore, a pressure sensor 158 is provided to measure the positive pressure, and is used in combination with the second elastic member 157 and the bottle cap 155, so that the bottle cap 155 bears part of the pressure under the action of the second elastic member 157, and only allows the injection needle to extend into the sample container. The structure is simple and the cost is low.

[0091] Combination Figure 1 , Figure 20 to Figure 22 As shown, the transmission mechanism 105 includes a transmission plate 159 and a transmission belt 160 disposed on the transmission plate 159. The transmission belt 160 is disposed parallel to the positioning shaft 146 and is in transmission connection with the first transmission shaft 111. The fixed bracket 106 is connected to the transmission belt 160. The bottle pressing member 145 is disposed at the bottom of the positioning shaft 146 and partially extends horizontally to the bottom of the transmission belt 160 to press the sample container downward (such as Fig. 20 and Fig. 22 The top of the sample injection bottle 108 is shown.

[0092] In actual application, the fixed bracket 106 of the automatic sampler 10 is integrally connected with the bottle presser assembly 107, and the fixed bracket 106 is used to fix the injection needle. The first driving mechanism 135 drives the first transmission shaft 111 to rotate, so as to drive the fixed bracket 106 and the bottle presser assembly 107 to move up and down together. The second driving mechanism 133 drives the sample tray assembly 114 to make a circular motion. The third driving mechanism 134 drives the third transmission shaft 113 to rotate, and drives the transmission mechanism 105 to make a horizontal motion. Among them, the multiple second transmission shafts 112 play a role of constraint.

[0093] The automatic sampler 10 includes a sample suction process. During the sample suction process, the first driving mechanism 135 drives the first transmission shaft 111 to rotate, driving the fixed bracket 106, the injection needle and the bottle pressing assembly 107 to move downward together. When the bottle pressing member 145 of the bottle pressing assembly 107 hits the top of the sample suction bottle (not shown in the figure), the first elastic member 147 is triggered to compress, and the bottle pressing member 145, the positioning shaft 146, the grating 148, and the second fixed member 153 are stationary. At this time, the fixed bracket 106, the injection needle and the first fixed member 150 and the light triggering member 149 connected to the fixed bracket 106 move downward. Wherein the fixed bracket 106 drives the injection needle to move downward relative to the bottle pressing member 145 to extend into the sample suction bottle for sample suction. And after completing the sample suction, the fixed bracket 106 drives the injection needle and the first fixed member 150 and the light triggering member 149 to move upward. During this process, the first elastic member 147, the bottle pressing member 145, the positioning shaft 146, the grating 148 and the second fixing member 153 are reset upward, and the sampling needle is withdrawn from the sample suction bottle at the same time.

[0094] The automatic sampler 10 includes a sample injection process. During the sample injection process, the first driving mechanism 135 drives the first transmission shaft 111 to rotate, driving the fixed bracket 106, the sample injection needle and the bottle pressing assembly 107 to move downward together. When the bottle pressing member 145 of the bottle pressing assembly 107 hits the bottle cap 155, the first elastic member 147 is triggered to be compressed, and the bottle pressing member 145, the positioning shaft 146, the grating 148, and the second fixing member 153 are stationary. At this time, the fixed bracket 106, the sample injection needle, and the first fixing member 150 and the light triggering member 149 connected to the fixed bracket 106 move downward. The fixed bracket 106 drives the sample injection needle to move downward relative to the bottle pressing member 145 to extend into the sample suction bottle. The force of the injection needle inserted into the injection seat 156 is transmitted to the pressure sensor 158 through the second elastic member 157. The pressure sensor 158 detects the pressure of the injection needle applied to the injection seat 156. When the pressure sensor 158 detects that the pressure reaches the pressure threshold, the controller controls the first driving mechanism 135 to stop driving the first transmission shaft 111 to rotate to start injection.

[0095] With such arrangement, the fixed bracket 106 is elastically connected to the bottle press assembly 107, so that the bottle pressing action can be realized when aspirating samples, and the bottle cap 155 can be used to block the pressure of the bottle press assembly 107 when injecting samples, thereby achieving the same function while reducing a set of motion mechanisms, effectively reducing product costs and improving market competitiveness.

[0096] The above description is only a preferred embodiment of the present application and is not intended to limit the present application. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present application shall be included in the scope of protection of the present application.

Claims

1. An automatic sample injector, characterized in that: include: At least two brackets arranged opposite to each other, the brackets extending up and down; A first transmission shaft, disposed between at least two of the brackets; a fixed bracket movably connected to the first transmission shaft; An injection needle, fixed to the fixed bracket; A sample container is arranged below the fixed bracket; a bottle press assembly connected to the fixed bracket and movable up and down relative to the first transmission shaft, wherein the bottle press assembly can be located at a first position or a second position, wherein the bottle press assembly is separated from the sample container in the first position and pressed against the top surface of the sample container in the second position; and a first driving mechanism, disposed on the bracket and connected to the first transmission shaft; the first driving mechanism is used to drive the first transmission shaft to rotate, drive the fixed bracket and the bottle press assembly to move up and down, and move the bottle press assembly between the first position and the second position; and when the bottle press assembly is in the second position, drive the first transmission shaft to rotate, drive the fixed bracket to move up and down relative to the bottle press assembly, and insert or remove the injection needle into or out of the sample container; Wherein, the bottle press assembly includes a bottle press member, a positioning shaft and a first elastic member; the positioning shaft extends up and down, the bottle press member is arranged at the bottom of the positioning shaft, the first elastic member is sleeved on the positioning shaft, and the fixed bracket is arranged at the top of the first elastic member and is connected to the positioning shaft; the bottle press assembly also includes a first fixing member, which is arranged at the top of the first elastic member and is fixedly connected to the fixing bracket; the fixing bracket includes a bracket slot extending up and down, the first fixing member is provided with a through hole passing through up and down, the positioning shaft is passed through the through hole, the top of the bracket slot is pressed against the top surface of the first fixing member, the bottom surface of the first fixing member is pressed against the top of the first elastic member, and the side surface of the first fixing member is clamped with the side wall of the bracket slot.

2. The automatic sample injector according to claim 1, characterized in that: When the bottle pressing assembly is in the first position, the bottle pressing member is separated from the sample container, the fixed bracket, the top of the first elastic member and the top of the positioning shaft are connected, and the first driving mechanism is used to drive the first transmission shaft to rotate, thereby driving the fixed bracket, the bottle pressing member, the positioning shaft and the first elastic member to move up and down together; When the bottle press assembly is in the second position, the bottle press member presses against the top surface of the sample container, the first driving mechanism is used to drive the first transmission shaft to rotate, and drive the fixed bracket to move up and down relative to the positioning shaft, the top of the fixed bracket and the first elastic member are separated from the top of the positioning shaft, and the first elastic member elastically deforms up and down to interact with the fixed bracket.

3. The automatic sample injector according to claim 2, characterized in that: The bottle pressing assembly further comprises a grating and a light triggering member, wherein the grating is fixedly arranged on the top of the positioning shaft, and the light triggering member is arranged on the top of the first elastic member and is fixedly connected to the fixing bracket and the top of the first elastic member; When the bottle pressing assembly is in the first position, the optical trigger is connected to the grating, the fixed bracket, the top of the first elastic member and the top of the positioning shaft are connected, and the first driving mechanism is used to drive the first transmission shaft to rotate, thereby driving the fixed bracket, the optical trigger and the grating to move up and down together; When the bottle press assembly is in the second position, the first driving mechanism is used to drive the first transmission shaft to rotate, thereby driving the fixed bracket and the light triggering component to move up and down together relative to the grating, and the light triggering component is separated from the grating. The grating is used to detect the movement distance of the fixed bracket relative to the positioning shaft, so as to detect the movement distance of the injection needle.

4. The automatic sample injector according to claim 3, characterized in that: The light triggering component is fixed to the first fixing component.

5. The automatic sample injector according to claim 4, characterized in that: When the bottle press assembly is in the second position, the first driving mechanism is used to drive the first transmission shaft to rotate, thereby driving the fixing bracket and the first fixing member to move up and down relative to the positioning shaft.

6. The automatic sample injector according to claim 4, characterized in that: The bottle press assembly also includes a second fixing member fixedly arranged on the top of the positioning shaft, and the grating is arranged on the second fixing member.

7. The automatic sample injector according to claim 2, characterized in that: The sample container includes a sample injection bottle, which is arranged below the bottle presser assembly; the sample injection bottle includes an outer shell, a bottle cap arranged on the outer shell, and a sample injection seat arranged in the outer shell; when the bottle presser assembly is in the second position, the bottle pressing member presses against the top surface of the bottle cap, and the first driving mechanism is used to drive the first transmission shaft to rotate, drive the fixed bracket to press the first elastic member to move up and down relative to the positioning shaft, and drive the sample injection needle to move up and down together with the bottle cap to insert or remove the sample injection seat.

8. The automatic sample injector according to claim 7, characterized in that: The injection bottle also includes a second elastic member and a pressure sensor arranged in the outer shell, the pressure sensor is arranged at the bottom of the outer shell, and the pressure sensor is elastically connected to the injection seat through the second elastic member; when the bottle presser assembly is in the second position, the bottle presser is pressed against the top surface of the bottle cap, and when the injection needle moves downward relative to the bottle cap and is inserted into the injection seat, the pressure sensor is used to detect the pressure of the injection needle on the injection seat, and the automatic sampler includes a controller, and the controller is used to control the first driving mechanism to stop driving the first transmission shaft to rotate when the pressure sensor detects that the pressure reaches a pressure threshold.

9. The automatic sample injector according to claim 2, characterized in that: The automatic sampler also includes a sample tray assembly, the sample container includes a sample suction bottle, and the sample tray assembly accommodates the sample suction bottle; when the bottle press assembly is in the second position, the injection needle extends into the sample suction bottle to suck the sample.

10. The automatic sample injector according to claim 1, characterized in that: The fixing bracket comprises a locking needle groove and an elastic component fixedly connected to the locking needle groove, wherein the elastic component clamps the injection needle so that the injection needle is fixed in the locking needle groove and can be elastically deformed relative to the locking needle groove to allow the injection needle to be inserted or removed; and / or The fixing bracket is an integrated structure.

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