A kind of donkey-hide gelatin peptide for delaying aging and its preparation method and application
Through ultra-fine crushing and enzymatic treatment of donkey-hide gelatin, donkey-hide gelatin peptides with excellent antioxidant properties were prepared, which solved the problem of long preparation and low bioavailability in the prior art, and achieved the effect of delaying the aging of the body.
CN118516438BActive Publication Date: 2025-03-21SHANDONG DONGE AORUN DONKEY-HIDE GELATIN CO LTD
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Patent Information
- Application Number
- CN202410997420.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-24
- Publication Date
- 2025-03-21
- Estimated Expiration
- 2044-07-24
AI Technical Summary
Technical Problem
The existing preparation methods of donkey-hide gelatin peptides take a long time, have low bioavailability, and lack effective roles in delaying body aging.
Method used
By ultra-fine pulverizing donkey-hide gelatin and mixing it with aqueous citrate solution, treatment in a boiling state, complex enzyme (composed of collagenase and papain) is added for enzymatic decomposition, and then dried after centrifugation, ultrafiltration, donkey-hide gelatin peptide with excellent antioxidant properties is prepared.
Benefits of technology
It significantly shortens the preparation time of donkey-hide gelatin peptide, improves its antioxidant properties, and proves in animal experiments that it can delay the aging of the body.
✦ Generated by Eureka AI based on patent content.
Abstract
The present invention provides a kind of donkey-hide gelatin peptide for delaying aging and its preparation method and application, belonging to the field of biotechnology. The preparation method of the donkey-hide gelatin peptide for delaying aging of the present invention comprises: mixing the ultrafine grinding of donkey-hide gelatin with a citric acid aqueous solution, treating it for 60min-90min under a boiling water state, adding a composite enzyme enzymolysis, and drying the obtained filtrate after centrifugation and ultrafiltration to obtain the donkey-hide gelatin peptide. Ultrafine grinding increases the reaction surface area of donkey-hide gelatin; the citric acid aqueous solution can break the peptide bond of the donkey-hide gelatin protein molecule and promote the hydrolysis reaction; the boiling water state puts the reaction system in a vibrating state and shortens the reaction time; the composite enzyme enzymolysis accurately controls the degree of enzymolysis to obtain the donkey-hide gelatin peptide for delaying aging. The experimental results show that the donkey-hide gelatin peptide of the present invention has excellent antioxidant properties, can increase the content of SOD, GSH-Px, and CAT in the plasma of D-galactose-induced aging mice, reduce the content of MDA, and play a role in delaying aging.
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