Passive sampling device for efficiently adsorbing trace psychotropic drugs in ambient air

Abstract

The invention relates to the technical field of air monitoring, and discloses a passive sampling device for efficiently adsorbing trace psychotropic drugs in ambient air, which sequentially comprises a bonding layer, a PET plastic film, a foam layer, an adsorption material layer and a surface foam layer from bottom to top, a first through hole is formed in the center area of the foam layer in a penetrating mode, and the penetrating direction of the first through hole is perpendicular to the plane where the foam layer is located. A second through hole is formed in the center area of the surface foam layer in a penetrating mode, and the penetrating direction of the second through hole is perpendicular to the plane where the surface foam layer is located. The passive sampling device for efficiently adsorbing trace psychotropic drugs in ambient air provided by the invention is light and convenient, is simple to mount and dismount, can be mounted at different positions of a public area, has a good monitoring effect while not easily causing alertness, realizes efficient and low-cost reduction of a drug-related investigation range, and has important significance on drug prevention and control in China.

Description

Technical Field

[0001] The present application relates to the field of air monitoring technology, and mainly to a passive sampling device for efficiently absorbing trace amounts of psychotropic drugs in ambient air. Background Art

[0003] In the actual case investigation process, the environment is generally wiped with a cotton swab containing a solvent such as methanol, and then the cotton swab is subjected to a series of pre-treatments and analyzed by a liquid chromatography-tandem mass spectrometer. These trace amounts of drug substances attached to the surface of environmental objects can be detected, which plays a great role in the detection of drug abuse cases. However, this active sampling method cannot accurately distinguish the specific time of drug abuse, and there are also problems such as the inability to serve as an early warning for drug abuse in a specific space. Moreover, most of the existing passive air sampling devices are generally complex in structure, large in size, difficult to install, and cannot play a good monitoring role. Therefore, it is necessary to propose a passive sampling device that can efficiently adsorb trace psychotropic drugs in the ambient air for monitoring and reduce the abuse of narcotic drugs. Therefore, the existing technology still needs to be improved and developed. Summary of the invention

[0004] In view of the above-mentioned deficiencies in the prior art, the purpose of this application is to provide a passive sampling device for efficiently adsorbing trace amounts of psychotropic drugs in ambient air, aiming to solve the problems that the existing passive air sampling devices are complex in structure, large in size, difficult to install, and cannot play a good monitoring role.

[0005] The technical solution of this application is as follows: The present application provides a passive sampling device for efficiently absorbing trace psychotropic drugs in ambient air, wherein the device comprises, from bottom to top, an adhesive layer, a PET plastic film, a foam layer, an adsorption material layer and a surface foam layer; A first through hole is provided in the central area of ​​the foam layer, and the penetration direction of the first through hole is perpendicular to the plane where the foam layer is located; A second through hole is provided in the central area of ​​the surface foam layer, and a penetrating direction of the second through hole is perpendicular to the plane where the surface foam layer is located.

[0006] The passive sampling device for efficiently adsorbing trace amounts of psychotropic drugs in ambient air provided in the present application is light and convenient, and has the characteristics of flexibility, convenience, concealment, low cost and high efficiency. While maintaining a light size, it has good adsorption performance, is easy to install and disassemble, is easy to disguise, has good concealment, can realize efficient and flexible detection, is not easy to cause alarm, and realizes efficient and flexible monitoring.

[0007] Furthermore, the outer boundaries of the adhesive layer, the PET plastic film, the foam layer, the adsorption material layer and the surface foam layer are all square; The cross-sectional shapes of the first through hole and the second through hole are circular.

[0008] In the present application, by setting the shape difference between the square and the circular passage, air can flow more easily through the relatively weak points therein, and the air can play a certain convergence and concentration role when passing through, thereby improving the degree of adsorption.

[0009] Further, a diameter of the first through hole is greater than a diameter of the second through hole.

[0010] In the present application, by controlling the diameters of the first through hole and the second through hole, the air is more likely to pass through the adsorption material layer and then flow out of the foam layer, rather than just staying on the surface foam layer, thereby increasing the air flux flowing through the adsorption material layer, which is more conducive to improving the adsorption effect, and the detection effect when applied to the elevator is also better. Furthermore, the side length of the square is 40 mm; The diameter of the first through hole is 35 mm, and the diameter of the second through hole is 32 mm.

[0011] Furthermore, a central area of ​​the adsorption material layer is recessed toward the foam layer.

[0012] Furthermore, the thickness of the foam layer is 5 mm, the thickness of the adsorption material layer is 0.1-3 mm, and the thickness of the surface foam layer is 2 mm; The distance of the recess is 1.5 mm.

[0013] Furthermore, the adsorption material layer is made of one of polyurethane sponge, activated carbon polyester fiber filter cotton and polyester non-woven fabric.

[0014] Furthermore, the adsorption material layer is made of polyurethane sponge.

[0015] Further, the polyurethane sponge is a low-density polyurethane sponge; The density of the low-density polyurethane sponge is 18kg / m³.

[0016] Furthermore, the adhesive layer is 3M double-sided tape.

[0017] Beneficial effects: The passive sampling device for efficiently adsorbing trace amounts of psychotropic drugs in ambient air provided in the present application is light and convenient, easy to install and disassemble, can be installed in different locations in public areas, is not easy to cause alarm and plays a good monitoring role. It can achieve efficient and low-cost reduction of the scope of drug-related investigations, which is of great significance to drug prevention and control in my country. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 This is a schematic diagram of the structure of a passive sampling device for efficiently adsorbing trace amounts of psychotropic drugs in ambient air according to the present application.

[0019] Figure 2 This is a top view of the passive sampling device for efficiently adsorbing trace amounts of psychotropic drugs in ambient air in the present application.

[0020] Figure 3 This is a three-dimensional schematic diagram of a passive sampling device for efficiently adsorbing trace amounts of psychotropic drugs in ambient air according to the present application.

[0021] Figure 4 This is a schematic diagram of the cross-sectional structure of the central area of ​​a passive sampling device for efficiently adsorbing trace amounts of psychotropic drugs in ambient air according to the present application.

[0022] Figure 5 In Example 1 of the present application, an adsorption material layer of low-density polyurethane sponge was used.

[0023] Figure 6 In Example 2 of the present application, an adsorption material layer of activated carbon polyester fiber filter cotton was used.

[0024] Figure 7 In Example 3 of the present application, an adsorbent material layer of polyester nonwoven fabric was used.

[0025] Figure 8 This is a schematic diagram of a box positive experiment of a passive sampling device for efficiently adsorbing trace amounts of psychotropic drugs in ambient air according to Examples 1-3 of the present application.

[0026] Fig. 9 This is a schematic diagram of a passive sampling device for efficiently adsorbing trace amounts of psychotropic drugs in ambient air according to Examples 1-3 of the present application installed at a ventilation port.

[0027] Fig.10 This is a schematic diagram of a passive sampling device for efficiently adsorbing trace amounts of psychotropic drugs in ambient air according to Examples 1-3 of the present application installed on a door frame.

[0028] Explanation of reference numerals: 1. adhesive layer; 2. PET plastic film; 3. foam layer; 31. first through hole; 4. adsorption material layer; 5. surface foam layer; 51. second through hole. DETAILED DESCRIPTION

[0029] The present application provides a passive sampling device for efficiently absorbing trace psychotropic drugs in ambient air. To make the purpose, technical solution and effect of the present application clearer and more specific, the present application is further described in detail below. It should be understood that the specific embodiments described herein are only used to explain the present application and are not used to limit the present application.

[0030] Most of the existing air sampling devices are large in size and difficult to install. They are usually placed or hung for use and are not very concealed. When sampling narcotic and psychotropic drugs, they are likely to arouse the vigilance of the monitored population and cannot play a good monitoring role.

[0031] Regarding this issue, Figure 1-4 As shown, the present application provides a passive sampling device for efficiently adsorbing trace amounts of psychotropic drugs in ambient air, wherein, from bottom to top, it includes an adhesive layer 1, a PET plastic film 2, a foam layer 3, an adsorption material layer 4 and a surface foam layer 5.

[0032] The passive sampling device for efficiently adsorbing trace amounts of psychotropic drugs in ambient air provided in the present application is light and convenient, easy to install and disassemble, can be installed in different locations in public areas, is not likely to cause alarm and at the same time plays a good monitoring role, and can achieve the goal of reducing the scope of drug-related investigations efficiently and at low cost.

[0033] In the present application, a loose and porous foam layer 3 and a surface foam layer 5 are used on both sides of the adsorption material layer 4 to facilitate airflow, thereby increasing the degree of contact between the adsorption material layer 4 and the air. The adsorption material layer 4 can absorb aerosols carrying target detection objects through direct contact.

[0034] Furthermore, a first through hole 31 is provided in the central area of ​​the foam layer 3, and the through direction of the first through hole 31 is perpendicular to the plane where the foam layer 3 is located; A second through hole 51 is provided in the central area of ​​the surface foam layer 5 , and the penetrating direction of the second through hole 51 is perpendicular to the plane where the surface foam layer 5 is located.

[0035] Specifically, in the present application, by setting a second through hole 51 in the central area of ​​the surface foam layer 5, the covered adsorption material layer 4 is directly exposed to adsorb the target object. Moreover, during sampling, natural wind or people walking will generate a certain amount of flowing airflow. In the present application, by setting a through hole in the surface foam layer 5, the surface foam layer 5 can form a level difference (height difference) with the through hole, so that when the flowing air flows through the surface of the foam layer 3, it can form a certain vortex at the edge of the through hole and then pass through the adsorption material layer 4, which is conducive to improving the adsorption effect on the target object and achieving the monitoring effect.

[0036] Furthermore, in the present application, by providing the first through hole 31 in the foam layer 3, in conjunction with the second through hole 51, the air flow on both sides of the adsorption material layer 4 can be further improved, so that the flowing airflow or the diffused aerosol can more easily pass through the adsorption material layer 4 and be adsorbed. Moreover, after providing the first through hole 31, the air flow of the foam layer 3 is improved, and part of the air can more easily pass through the foam layer 3, so that when the air flows in the foam layer 3, it is also easy to drive the air to pass through the adsorption material layer 4, which is also conducive to improving the adsorption effect.

[0037] Among them, since the adhesive layer 1 is provided and the first through hole 31 is opened on the foam layer 3, the PET plastic film 2 is provided between the adhesive layer 1 and the foam layer 3 to prevent the adhesive layer 1 from adhering to the exposed adsorption material layer 4 and affecting the adsorption effect, and also facilitate the subsequent splitting and testing. Specifically, in combination with the on-site installation and laboratory testing conditions, in the exposed area of ​​the adsorption material layer 4, a circular fine line with an area slightly smaller than the second through hole 51 can be engraved, and a four-divided pattern can be engraved on the circular fine line. The provided pattern can facilitate the equal-area splitting of the adsorption material during the detection and analysis, and is more efficient during mixed testing and continued screening testing.

[0038] Furthermore, the outer boundaries of the adhesive layer 1, the PET plastic film 2, the foam layer 3, the adsorption material layer 4 and the surface foam layer 5 are all square; The cross-sectional shapes of the first through hole 31 and the second through hole 51 are circular.

[0039] Among them, the outer boundary of the square specifically indicates that from the top view direction, the outer boundary of the passive sampling device for efficiently adsorbing trace psychotropic drugs in the ambient air is a square. In the present application, the first through hole 31 and the second through hole 51 are matched to set the cross-sectional shape to be circular, which can keep a larger adsorption area exposed while retaining the airflow adjustment effect. The sampling device is set to be square to cope with most monitoring scenarios, especially in some aisles or door positions, which are not easy to be detected by the monitored people, and because the flow and diffusion of air are usually directional, by setting the shape difference between the square and the circular through, the air is more likely to flow from the relatively weak points, and the air can play a certain convergence and concentration role when passing through, thereby improving the degree of adsorption. Moreover, the adsorption material layer 4 of the present application needs to be split for mixed inspection, and the shape matching can also improve the uniformity of adsorption on different areas of the adsorption material layer 4, which is more accurate when the adsorption material layer 4 is split for detection, avoiding the absorption of some areas that is too low and difficult to be detected, thereby affecting the detection effect.

[0040] Further, the diameter of the first through hole 31 is greater than the diameter of the second through hole 51 .

[0041] Specifically, the sampling device provided by the present application can also be set in an elevator, and the use effect is also better. The elevator is a relatively closed public space. Under the action of inertia, during the acceleration or deceleration stage of the elevator rising or falling, the movement speed of the air in the elevator is slower than that of the elevator, causing the elevator "ceiling" to press the air downward or the air to have a tendency to press toward the "ceiling", forming a specific air flow. Therefore, the sampling device placed on the "ceiling" in the elevator is more likely to capture substances in the air in the elevator, so it is a monitoring place with a better use effect of the sampling device.

[0042] In view of this usage scenario, in the present application, the diameter of the first through hole 31 of the foam layer 3 is set larger than the diameter of the second through hole 51 to improve the air flow of the foam layer 3, so that when the sampling device is pressed against the air, the air is more likely to pass through the adsorption material layer 4 and then flow out of the foam layer 3, rather than just staying on the surface foam layer 5. In this way, when moving up and down with the elevator, the air flux flowing through the adsorption material layer 4 can also be increased, which is more conducive to improving the adsorption effect. In actual monitoring, the use effect of the elevator is also better.

[0043] Furthermore, the side length of the square is 40 mm; the diameter of the first through hole 31 is 35 mm, and the diameter of the second through hole 51 is 32 mm.

[0044] Specifically, if the size of the through hole is set too large and the exposure is too high, the air cannot flow in the required adjustment direction when passing through the sampling device, which is easy to affect the adsorption effect. If the diameter of the through hole is too small, it will affect the degree of air flow in the passive sampling device. The present application takes into account the flow characteristics of the air, controls the overall size of the sampling device to match the size of the first through hole 31 and the second through hole 51, and strikes a balance between the miniaturization of the sampling device and the adsorption efficiency. Under this size difference, while maintaining the adsorption sensitivity, the adjustment effect on the air flow is also easy to reflect, which is conducive to improving the adsorption effect.

[0045] The passive air sampling device provided by the present application realizes miniaturization, is more flexible, convenient, concealed, low-cost and efficient, and can effectively realize monitoring. Among them, the circular fine lines on the adsorption material layer 4 can be set to be concentric circles coinciding with the center of the circular cross section of the second through hole, and the diameter of the circular fine lines can be specifically set to 30 mm.

[0046] Furthermore, if Figure 4 As shown, the central area of ​​the adsorption material layer 4 is recessed toward the foam layer 3 .

[0047] Specifically, by setting the center area of ​​the adsorption material layer 4 to be concave, the contact area of ​​the adsorption material layer 4 can be increased when the air flows directly through the adsorption material layer 4. If the air flows through the surface foam layer 5 of the sampling device, after the second through hole 51 forms a vortex, a certain arc of the concave can help the vortex to continue to be maintained for a certain period of time. In this way, whether the vortex continues to be maintained or diffuses with the concave, it can increase the degree of action of the airflow on the adsorption material layer 4, which is conducive to improving the adsorption effect. Moreover, the concave cooperates with the first through hole 31 of the foam layer 3 to form a certain narrow area in the foam layer 3. When air flow is generated in the foam layer 3 (such as a vent with a large air flux), it can also play a certain acceleration role and improve the adsorption degree of the target flow to the adsorption material layer 4.

[0048] Furthermore, the thickness of the foam layer 3 is 5 mm, the thickness of the adsorption material layer 4 is 0.1-3 mm, the thickness of the surface foam layer 5 is 2 mm; and the distance of the depression is 1.5 mm.

[0049] In the present application, by coordinating the thicknesses of the foam layer 3, the adsorption material layer 4 and the surface foam layer 5 and setting a depression degree of 1.5 mm, the depression degree is not large, but it can also play a certain airflow guiding effect when the air flows. At the same time, it does not affect the contact degree between the foam layer 3 and the air, and does not limit the required air flow effect.

[0050] Further, the material of the adsorption material layer 4 is one of polyurethane sponge, activated carbon polyester fiber filter cotton and polyester non-woven fabric. In the present application, the selected material has a good aerosol adsorption effect, which is conducive to detecting the target object.

[0051] Preferably, the material of the adsorption material layer 4 is polyurethane sponge. Polyurethane sponge has a good adsorption effect on substances in the air.

[0052] Furthermore, the polyurethane sponge is a low-density polyurethane sponge; the density of the low-density polyurethane sponge is 18kg / m³. In the present application, the selected low-density polyurethane sponge has the characteristics of lightness, softness, elasticity and strong air permeability. It has a strong specific surface area, can effectively adsorb substances in the air, has the potential for easy acquisition, low cost and wide application, and cooperates with the remaining flexible component layers. The prepared sampling device can also cope with the use in different scenarios, improving the monitoring effect and monitoring efficiency. In the passive sampling device provided in the present application, by using a low-density polyurethane sponge with a density of 18kg / m³, it is possible to facilitate the passage of air while adsorbing. If the density of the sponge is reduced, the degree of adsorption of the target object will be reduced, affecting the detection effect. If the density of the sponge is increased, the air flow effect will be affected, especially when the air humidity is high, the absorbed moisture is difficult to dissipate in time, and the degree of influence on the detection effect is higher.

[0053] Furthermore, the adhesive layer 1 is a 3M double-sided adhesive tape. By adopting the 3M double-sided adhesive tape, the sampling device is easy to install and monitor, and is also convenient for recycling and detection. The traces of recycling residues are also easy to remove, which has the advantages of high efficiency and low impact.

[0054] The passive sampling device for efficiently adsorbing trace amounts of psychotropic drugs in ambient air provided in the present application is light and convenient, and has the characteristics of flexibility, convenience, concealment, low cost and high efficiency. While maintaining a light size, it has good adsorption performance, and the materials are easy to obtain and inexpensive. It is easy to install and disassemble, easy to disguise, and has good concealment. It can realize efficient and flexible detection, is not easy to cause alarm, and realizes efficient and flexible monitoring.

[0055] The passive sampling device for efficiently absorbing trace psychotropic drugs in ambient air can be prepared by configuring each layer and then pasting them together. In large-scale preparation, the required feature array can also be configured on a large area of ​​raw materials, and then cut and divided according to the required size after pasting each layer in sequence. Large-scale preparation is simpler and faster, which helps to achieve all-weather, multi-directional drug monitoring, and is of great significance to my country's drug prevention and control.

[0056] The present application also provides a method for using the passive sampling device for efficiently adsorbing trace amounts of psychotropic drugs in ambient air as described above, which comprises the following steps: Paste the passive sampling device that can efficiently absorb trace amounts of psychotropic drugs in ambient air at the application scene and record the installation time; After the monitoring is completed, wear gloves to remove the passive sampling device that efficiently absorbs trace amounts of psychotropic drugs in the ambient air and put it into the evidence bag, and simultaneously record the specific time period and location of the monitoring on the surface of the evidence bag; After the samples are recovered, they will be sent to the laboratory for testing within 24 hours.

[0057] Among them, when the adhesive layer 1 is in use with 3M double-sided tape, the tape of the bottom double-sided tape can be torn off and then pasted. After removal, the bottom double-sided tape can continue to remain on the surface of the environmental object, which is convenient for the subsequent installation of a passive sampling device that efficiently adsorbs trace amounts of psychotropic drugs in the ambient air without the adhesive layer 1, thereby reducing the cost of large-scale long-term monitoring.

[0058] This passive sampling device for efficiently adsorbing trace amounts of psychotropic drugs in ambient air is easy to install and disassemble. Customers can install it themselves after simple training and it can be sent to the laboratory after sampling.

[0059] The present application also provides a detection method for the passive sampling device for efficiently adsorbing trace amounts of psychotropic drugs in ambient air as described above, which comprises the following steps: The passive sampling device that efficiently adsorbs trace amounts of psychotropic drugs in ambient air was divided into four samples; Place one of the samples in a centrifuge tube, add a certain proportion of methanol-water solution, sonicate for 15-30 minutes, and vortex for 1 minute; Filter, and analyze the filtrate by liquid chromatography tandem mass spectrometry.

[0060] The splitting into four samples can be done in a sealed environment, such as a sealed evidence bag, to avoid contamination. The amount and concentration of methanol-water solution can be adjusted according to actual conditions to ensure that the adsorbed target is dissolved for testing. This detection method is simple and fast to handle, and can achieve a "mixed test + splitting" detection method, saving testing costs and gaining favor from customers.

[0061] By using the passive sampling device of the present application for efficiently absorbing trace amounts of psychotropic drugs in ambient air, it is possible to monitor the possible use of electronic cigarette drugs during the installation period in a specific space. The police can use the monitoring information of this period to cooperate with other clues to conduct in-depth investigations and improve the efficiency of handling cases. The passive air sampling device can monitor entertainment venues: (1) KTV, hotel private rooms and other places with small spaces and large numbers. Installed in the exhaust vents, walls, and floors in front of the door in the room. Since there are many rooms, the "mixed inspection + split" mode can be adopted to save costs. Once drugs are detected, the suspect can be identified by combining clues such as room booking information. (2) Bars, game halls, clubs, foot massage shops and other places with large spaces and high personnel mobility. Installed in the exhaust vents, walls, floors in front of the door, desktops, etc. in the room. Multiple environmental passive samplers can be installed in one space, and multiple samplers can be mixed for inspection. Once drugs are detected, the suspect can be identified by combining clues such as surveillance videos, purchase of services and product information. It can also monitor communities with drug-related clues: it can be installed in public areas of each building, such as the lobby, elevator hall, and the floor, ceiling, and wall areas inside the elevator. Through the "mixed inspection + split" model, the scope of drug-related investigation can be narrowed down efficiently and at low cost.

[0062] The passive sampling device for efficiently adsorbing trace amounts of psychotropic drugs in ambient air provided in the present application is light, convenient, flexible, efficient, and well concealed, and can be simply installed in an inconspicuous location. For cities involved in drug situations, it has a better cost-effectiveness, lower cost, and faster results in tracing scattered drug users.

[0063] The invention is further described below by means of specific examples.

[0064] Example 1 The method for preparing the passive sampling device for efficiently adsorbing trace amounts of psychotropic drugs in ambient air of Example 1 comprises the following steps: Prepare 40×40mm 3M double-sided tape, align and stick the 40×40mm PET plastic film 2 on the 3M double-sided tape; A circular through hole with a diameter of 35 mm is opened in the central area of ​​the 40×40 mm foam layer 3 (5 mm thick), and the foam layer 3 is aligned and pasted on the PET plastic film 2; A circular fine line with a radius of 30 mm is carved in the central area of ​​a 40×40 mm low-density polyurethane sponge (3 mm thick, density of 18 kg / m³), and a fine line is carved to divide the circle into four equal parts. A depression is pressed in the central area with a tool, and the low-density polyurethane sponge is aligned and pasted on the foam layer 3 to obtain an adsorption material layer 4; A circular through hole with a diameter of 32 mm was opened in the central area of ​​the 40×40 mm surface foam layer 5 (2 mm thick), and the surface foam layer 5 was aligned and pasted on a low-density polyurethane sponge to obtain the passive sampling device for efficiently adsorbing trace amounts of psychotropic drugs in ambient air of Example 1.

[0065] The penetrating direction of the circular through hole is perpendicular to the plane of the layer where the circular through hole is located. Alignment and pasting indicate that the outer boundaries between each layer are aligned to ensure that the passive sampling device has a regular shape. The central area of ​​the low-density polyurethane sponge (adsorbent material layer 4) is concave toward the foam layer 3, and the concave distance is 1.5 mm. The low-density polyurethane sponge material is soft and stretchable, and the concave can be directly pressed out. When preparing with other materials, a slightly larger adsorbent material layer 4 can also be used to facilitate the setting of the concave, and then trimming can be performed after pasting is completed.

[0066] Example 2 The preparation method of Example 2 is basically the same as that of Example 1, with the only difference being that the low-density polyurethane sponge is replaced with a 3 mm thick activated carbon polyester fiber filter cotton to obtain the passive sampling device of Example 2 for efficiently adsorbing trace amounts of psychotropic drugs in ambient air.

[0067] Example 3 The preparation method of Example 3 is basically the same as that of Example 1, with the only difference being that the low-density polyurethane sponge is replaced with a 0.1 mm thick polyester non-woven fabric, thereby obtaining the passive sampling device of Example 3 for efficiently adsorbing trace amounts of psychotropic drugs in ambient air.

[0068] In Examples 1-3, multiple passive sampling devices for efficiently absorbing trace amounts of psychotropic drugs in ambient air were prepared for standby use. The effect diagrams of Examples 1-3 after the 3M double-sided adhesive tape and PET plastic film 2 were torn off after preparation are shown in the following table. Figure 5-7 shown.

[0069] The monitoring performance of the passive sampling device for efficiently adsorbing trace amounts of psychotropic drugs in ambient air prepared in Examples 1-3 was verified, and the monitoring method was as follows: 1. Box positive test: like Figure 8 As shown, the passive sampling devices for efficiently adsorbing trace amounts of psychotropic drugs in ambient air prepared in Examples 1-3 were subjected to a positive box experiment, comprising the following steps: Prepare cartons and lids; The passive sampling devices for efficiently adsorbing trace amounts of psychotropic drugs in ambient air prepared in Examples 1-3 were respectively pasted on the bottom of the carton; Place the box cover upside down on a flat surface (the surface of the box cover is placed downwards), light a cigarette soaked in electronic cigarette oil (containing isopapate, seized), and insert it into the box cover, then turn the carton upside down on the box cover to close it; After the cigarette is completely burned, let it stand for 10 minutes, repeat three times, take out the passive sampling devices for efficiently adsorbing trace amounts of psychotropic drugs in the ambient air prepared in Examples 1-3, put them into evidence bags respectively, and wipe the inner wall of the carton with a cotton swab.

[0070] 2. Real environment experiment: According to information provided by the Narcotics Control Team of a district police station in a certain city, several "high-intake e-cigarette" smokers were recently arrested on the 21st floor of Building 5 of Country Garden Apartments in a certain district, and it is suspected that there may also be "high-intake e-cigarette" smokers in households 306 and 307. According to on-site investigations, cameras were installed in the elevator hall, inside the elevator, and in the corridors on each floor of the residential building. Based on the above situation, the following experimental work was conducted: 1. The passive sampling devices of Examples 1-3 for efficiently absorbing trace amounts of psychotropic drugs in ambient air were installed on the ceilings of the four elevators in Building 5.

[0071] 2. The passive sampling devices for efficiently absorbing trace amounts of psychotropic drugs in ambient air of Examples 1-3 were installed at the rooftop main air outlets of Units 306 and 307. The installation effect is as follows: Fig. 9 shown.

[0072] 3. The passive sampling device for efficiently absorbing trace amounts of psychotropic drugs in ambient air of Examples 1-3 was installed on the top of the door frame of Households 306 and 307. The installation effect is as follows: Fig.10 shown.

[0073] The experimental time and weather conditions are shown in Table 1: Table 1

[0074] The collected samples of Examples 1-3 were placed in a centrifuge tube, methanol-water solution was added to dissolve the target, ultrasonicated for 30 minutes, vortexed for 1 minute; filtered, and the filtrate was analyzed and detected by liquid chromatography-tandem mass spectrometry. Taking the detection results of isopapate as an example, the samples of Examples 1-3 were tested and data analyzed, and the adsorption performance of the adsorption materials used in Examples 1-3 was preliminarily analyzed and compared. The experimental data of the box positive experiment (isopropagate) and the real environment experiment (isopropagate) of the passive sampling device for efficient adsorption of trace psychotropic drugs in ambient air of Examples 1-3 are shown in Table 2 (numeric unit: ng): Table 2

[0075] It can be seen from the positive experimental data of the box in Table 2 that the adsorption performance of the low-density polyurethane sponge used in Example 1 is optimal at high concentration values. It can be seen from the data of different embodiments in real environments that the detection data of the elevator is relatively high. Since the elevator is relatively closed, the degree of interaction between the air and the sampling device under the action of inertia is high, and the actual measured value is also high. Therefore, the elevator is a good place to use the passive sampling device for efficiently adsorbing trace psychotropic drugs in the ambient air of the embodiment of the present application.

[0076] The passive sampling device for efficiently adsorbing trace amounts of psychotropic drugs in ambient air provided in the embodiment of the present application is light and convenient, easy to install and disassemble, can be installed in different locations in public areas, is not likely to cause alarm and at the same time plays a good monitoring role, and can achieve the goal of reducing the scope of drug-related investigations efficiently and at low cost.

[0077] It should be understood that the application of the present application is not limited to the above examples. For ordinary technicians in this field, improvements or changes can be made according to the above description, and all these improvements and changes should fall within the scope of protection of the present application.

Claims

1. A passive sampling device for efficiently absorbing trace amounts of psychotropic drugs in ambient air, characterized in that: It comprises, from bottom to top, an adhesive layer (1), a PET plastic film (2), a foam layer (3), an adsorption material layer (4) and a surface foam layer (5); A first through hole (31) is provided in the central area of ​​the foam layer (3), and the penetration direction of the first through hole (31) is perpendicular to the plane where the foam layer (3) is located; A second through hole (51) is provided in the central area of ​​the surface foam layer (5), and the penetration direction of the second through hole (51) is perpendicular to the plane where the surface foam layer (5) is located.

2. The passive sampling device for efficiently adsorbing trace amounts of psychotropic drugs in ambient air according to claim 1 is characterized in that: The outer shapes and boundaries of the adhesive layer (1), the PET plastic film (2), the foam layer (3), the adsorption material layer (4) and the surface foam layer (5) are all square; The cross-sectional shapes of the first through hole (31) and the second through hole (51) are circular.

3. The passive sampling device for efficiently adsorbing trace amounts of psychotropic drugs in ambient air according to claim 2 is characterized in that: The diameter of the first through hole (31) is greater than the diameter of the second through hole (51).

4. The passive sampling device for efficiently absorbing trace amounts of psychotropic drugs in ambient air according to claim 3 is characterized in that: The side length of the square is 40 mm; The diameter of the first through hole (31) is 35 mm, and the diameter of the second through hole (51) is 32 mm.

5. The passive sampling device for efficiently absorbing trace amounts of psychotropic drugs in ambient air according to claim 4 is characterized in that: The central area of ​​the adsorption material layer (4) is recessed in a direction approaching the foam layer (3).

6. The passive sampling device for efficiently absorbing trace amounts of psychotropic drugs in ambient air according to claim 5 is characterized in that: The thickness of the foam layer (3) is 5 mm, the thickness of the adsorption material layer (4) is 0.1-3 mm, and the thickness of the surface foam layer (5) is 2 mm; The distance of the recess is 1.5 mm.

7. The passive sampling device for efficiently adsorbing trace amounts of psychotropic drugs in ambient air according to claim 1, characterized in that: The material of the adsorption material layer (4) is one of polyurethane sponge, activated carbon polyester fiber filter cotton and polyester non-woven fabric.

8. The passive sampling device for efficiently absorbing trace amounts of psychotropic drugs in ambient air according to claim 7 is characterized in that: The material of the adsorption material layer (4) is polyurethane sponge.

9. The passive sampling device for efficiently absorbing trace amounts of psychotropic drugs in ambient air according to claim 8, characterized in that: The polyurethane sponge is a low-density polyurethane sponge; The density of the low-density polyurethane sponge is 18kg / m³.

10. The passive sampling device for efficiently adsorbing trace amounts of psychotropic drugs in ambient air according to claim 1, characterized in that: The adhesive layer (1) is 3M double-sided adhesive.

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