Irradiation and sterilization all-in-one machine for medicine powder processing

Abstract

The irradiation and sterilization all-in-one machine comprises a machine box, and the interior of the machine box is divided into a drying area, a grinding area, a bagging and sealing area and an irradiation and sterilization area; a feeding port is formed above the drying area, and a hot air drying assembly is arranged at the top of the drying area; a first cooling area is arranged between the drying area and the grinding area, a first cooling assembly is arranged in the first cooling area, a grinding machine is arranged in the grinding area, and a first discharging inclined groove is formed in the side face of the grinding machine. A vacuum sealing device is arranged in the bagging sealing area; a second cooling area is arranged between the bagging sealing area and the irradiation sterilization area, and a second cooling assembly is arranged in the second cooling area; and an electron beam generator is arranged in the irradiation sterilization area. The operation steps of medicinal material drying, processing into powder, vacuum sealing subpackaging, cooling pretreatment, irradiation sterilization and the like are integrated in the same machine box, the probability that medicinal materials are polluted by bacteria in air in the processing process is reduced, the medicine effect of medicinal powder is further guaranteed, and the medication safety is improved.

Description

Technical Field

[0001] The invention relates to the technical field of radiation sterilization equipment, in particular to an integrated radiation sterilization machine for powder processing. Background Art

[0002] Pharmaceutical hygiene is an important part of drug production management, involving the entire process of drug production. At present, during the preparation process of Chinese medicine powder, it may be contaminated due to factors such as the operating environment, operating equipment, operating methods, and operating personnel, thus affecting the efficacy of the powder, and may even cause the drug to deteriorate and corrupt, producing substances that are harmful to the human body.

[0003] At present, Chinese medicine powder needs to be sterilized after processing. Common sterilization methods include dry heat sterilization, moist heat sterilization, microwave sterilization, irradiation sterilization, etc. Among them, irradiation sterilization has gradually become one of the main methods of sterilization. The advantages of irradiation sterilization include its strong penetration and ability to sterilize deep inside the substance, which is a major advantage over traditional sterilization methods. In addition, irradiation sterilization is also superior to heating and ethylene oxide chemical disinfection because it can effectively kill pathogenic microorganisms without heating and maintain the original quality and performance of the items.

[0004] The existing Chinese medicine powder is ground into powder, packed and sealed before being transferred to the irradiation sterilization equipment for irradiation sterilization. The whole process is relatively cumbersome, which reduces the processing efficiency of the medicine powder. Summary of the invention

[0005] In order to solve the above problems, the present invention provides an all-in-one irradiation sterilization machine for processing medicinal powder, which can directly process Chinese medicinal materials into medicinal powder and perform integrated bagging, sealing, and irradiation sterilization, thereby improving the processing efficiency of the medicinal powder.

[0006] To this end, the technical solution of the present invention is: an integrated radiation sterilization machine for powder processing, comprising a chassis, wherein the chassis is divided into a drying area, a grinding area, a bagging and sealing area, and a radiation sterilization area;

[0007] A feeding port is provided above the drying area, and a hot air drying component is provided on the top of the drying area;

[0008] A first cooling zone is provided between the drying zone and the grinding zone, the first cooling zone is provided with a first cooling assembly, and a first conveyor belt is provided between the drying zone and the first cooling zone;

[0009] A first lifting and feeding assembly is provided between the first cooling zone and the grinding zone, comprising a reversible tray and a tray lifting assembly;

[0010] A grinder is provided in the grinding area, and a first material discharge chute is provided on the side of the grinder;

[0011] A second lifting and feeding assembly is provided between the grinding area and the bagging and sealing area; a vacuum sealing device is provided in the bagging and sealing area;

[0012] A second cooling zone is provided between the bagging and sealing zone and the irradiation sterilization zone, and the second cooling zone is provided with a second cooling assembly;

[0013] A second conveyor belt is provided in the irradiation sterilization zone and the second cooling zone, an electron beam generator is provided in the irradiation sterilization zone, and a material discharge trough is provided on the side of the irradiation sterilization zone.

[0014] On the basis of the above scheme and as a preferred scheme of the above scheme: the hot air drying component includes a hot air disk, hot air outlets are evenly distributed on the hot air disk, and the hot air disk is connected to a hot air generator.

[0015] On the basis of the above scheme and as a preferred scheme of the above scheme: a first partition is provided between the first cooling zone and the drying zone, and the first conveyor belt is located below the first partition.

[0016] On the basis of the above scheme and as a preferred scheme of the above scheme: the first cooling component includes a cooling plate, cold air outlets are evenly distributed on the cooling plate, and the cooling plate is connected to a cold air fan.

[0017] On the basis of the above scheme and as a preferred scheme of the above scheme: the grinder includes a grinding bin and a vibrator, and the lower end of the grinding bin is installed on the vibrator; a trumpet-shaped feed port is provided above the grinding bin, and a group of grinding rollers working in cooperation with each other are provided below the feed port, and a screen is provided below the grinding rollers; the first discharge chute is connected to the bottom end of the grinding bin.

[0018] On the basis of the above scheme and as a preferred scheme of the above scheme: the pallet lifting assembly includes a vertically arranged lifting guide rail, a lifting screw is provided in the middle of the lifting guide rail, and a lifting motor connected to the lifting screw is provided on the top of the lifting guide rail; a base is slidably installed on the lifting guide rail, and a rotating motor is provided on the base. The output shaft of the rotating motor is connected to the pallet, which can drive the pallet to flip.

[0019] When in use, the cleaned medicinal materials are put into the chassis, and after being dried in the drying area, it is selected whether to perform the first cooling according to the shape of the medicinal materials; then the medicinal materials are sent to the tray of the first lifting and feeding component, the tray moves up, and the medicinal materials are poured into the grinding bin to be ground into powder; then the medicinal powder is sent to the vacuum sealing device by the tray of the second lifting and feeding component for bagging and vacuum sealing operations; the vacuum-sealed medicinal powder is sent to the second cooling area for low-temperature cooling, and after cooling for a certain period of time, it is sent to the bottom of the electron beam generator for irradiation sterilization operation, and finally the medicinal powder is discharged from the discharge chute.

[0020] Compared with the prior art, the beneficial effects of the present invention are as follows: the operation steps of drying medicinal materials, processing into powder, vacuum sealing and packaging, cooling pretreatment, irradiation sterilization, etc. are integrated in the same chassis, a sterile environment can be formed in the chassis, the probability of medicinal materials being contaminated by bacteria in the air during processing is reduced, the influence of human operation on the quality of medicinal powder is reduced, the efficacy of the medicinal powder is further guaranteed, and the safety of medication is improved. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 It is a structural schematic diagram of the present invention;

[0022] Figure 2 It is a structural schematic diagram of the drying zone of the present invention;

[0023] Figure 3 It is a structural cross-sectional view of the grinding machine of the present invention;

[0024] Figure 4 A top view of the structure of the vacuum sealing device of the present invention;

[0025] Figure 5 It is a structural schematic diagram of the irradiation sterilization area of ​​the present invention;

[0026] Figure 6 It is a working schematic diagram of the first lifting and feeding assembly of the present invention.

[0027] Marked in the figure are: chassis 1, drying zone 2, feeding port 21, hot air drying component 22, first cooling zone 3, first cooling component 31, grinding zone 4, grinding bin 41, vibrator 42, trumpet-shaped feeding port 43, grinding roller 44, screen 45, first unloading chute 46, bagging and sealing zone 5, bagging zone 51, bag holding zone 52, feeding zone 53, vacuum zone 54, unloading zone 55, second cooling zone 6, irradiation sterilization zone 7, electron beam generator 71, first conveyor belt 8, first lifting and feeding component 9, first tray 91, lifting guide rail 92, lifting screw 93, lifting motor 94, rotating motor 95, second lifting and feeding component 10, second conveyor belt 11. DETAILED DESCRIPTION

[0028] In the description of the present invention, it should be noted that directional words, such as the terms "center", "lateral (X)", "longitudinal (Y)", "vertical (Z)", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", etc., indicating directions and positional relationships are based on the directions or positional relationships shown in the accompanying drawings, which are only for the convenience of narrating the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and cannot be understood as limiting the specific scope of protection of the present invention.

[0029] In addition, the terms "first" and "second" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance or implicitly indicating the number of technical features. Therefore, the definition of "first" and "second" features can explicitly or implicitly include one or more of the features. In the description of the present invention, "several" and "a number" mean two or more, unless otherwise clearly and specifically defined.

[0030] See the attached drawings. The radiation sterilization integrated machine for powder processing described in this embodiment includes a chassis 1, which is divided into a drying area 2, a first cooling area 3, a grinding area 4, a bagging and sealing area 5, a second cooling area 6 and a radiation sterilization area 7. The chassis 1 is provided with a plurality of doors, each of which corresponds to a respective working area, and a visual window can be provided on the door.

[0031] A feeding port 21 is provided above the drying area 2 to facilitate the feeding of medicinal materials; a hot air drying component 22 is provided on the top of the drying area 2, and the hot air drying component includes a hot air disk with hot air outlets evenly distributed on the hot air disk. The hot air disk is connected to a hot air generator to dry the medicinal materials.

[0032] A first cooling zone 3 is provided between the drying zone 2 and the grinding zone 4. The first cooling zone 3 is provided with a first cooling assembly 31. The first cooling assembly 31 includes a cooling plate, and cold air outlets are evenly distributed on the cooling plate. The cooling plate is connected to a cold air blower. Some medicinal materials need to be cooled before grinding after drying, so cooling operation can be performed selectively.

[0033] A first partition is provided between the first cooling zone 3 and the drying zone 2, and a first conveyor belt 8 is provided in the drying zone and the first cooling zone. The first conveyor belt 8 is located below the first partition and can convey medicinal materials from the drying zone 2 to the first cooling zone 3, thereby facilitating the conveyance of medicinal materials.

[0034] A first lifting and feeding assembly 9 is provided between the first cooling zone 3 and the grinding zone 4, comprising a flippable first tray 91 and a tray lifting assembly; the first tray lifting assembly comprises a vertically arranged lifting guide rail 92, a lifting screw 93 is provided in the middle of the lifting guide rail, and a lifting motor 94 connected to the lifting screw is provided at the top of the lifting guide rail; a base is slidably installed on the lifting guide rail 92, and a rotating motor 95 is provided on the base, and the output shaft of the rotating motor is connected to the first tray 91, which can drive the first tray 91 to flip.

[0035] The grinding area 4 is provided with a grinder, which includes a grinding bin 41 and a vibrator 42. The lower end of the grinding bin 41 is mounted on the vibrator 42, and the vibrator 42 can drive the grinding bin 41 to vibrate, so as to facilitate material discharge and screening. A trumpet-shaped feed port 43 is provided above the grinding bin 41, and a group of grinding rollers 44 working in cooperation with each other are provided below the feed port. The grinding rollers 44 can grind the medicinal materials into powder. A screen 45 is provided below the grinding rollers 44, and the medicinal powder can be screened by the screen 45 to screen out medicinal powder of appropriate mesh size. A first material discharge chute 46 is provided on the side of the grinder near the bottom, and the medicinal powder can be discharged from the first material discharge chute 46 under the action of vibration.

[0036] A second lifting and feeding assembly 10 is provided between the grinding area 4 and the bagging and sealing area 5. The second lifting and feeding assembly 10 has the same structure as the first lifting and feeding assembly and is used to feed the medicine powder into the bagging and sealing area.

[0037] The bagging and sealing area 5 is provided with a vacuum sealing device, which is a conventional bag-feeding vacuum packaging machine, which is a mature technology and will not be described in detail. The bag-feeding vacuum packaging machine generally includes a bag-loading area 51, a bag-supporting area 52, a feeding area 53, a vacuum area 54 and a feeding area 55. The bag-loading area 51 can automatically load the bag and be opened in the bag-supporting area 52; the medicine powder is poured into the feeding funnel of the feeding area 53, and the powder is quantitatively added into the packaging bag from the bottom of the feeding funnel, and then the bag is sent to the vacuum area 54 for vacuum sealing.

[0038] A second cooling zone 6 is provided between the bagging and sealing zone 5 and the irradiation and sterilization zone 7. The second cooling zone 6 is provided with a second cooling assembly. The second cooling assembly 6 can use an existing conventional cooling method to pre-cool the bagged powder.

[0039] The irradiation sterilization area 7 and the second cooling area 6 are provided with a second conveyor belt 11, which can convey the powder in the two working areas; the irradiation sterilization area 7 is provided with an electron beam generator 71, which is a device capable of generating high-energy electron beams, which can generate radioactive rays such as X-rays and beta rays in application. These rays have high-energy characteristics, can penetrate substances, interact with substances, act on the DNA molecules of microorganisms, and cause the protein synthesis of microorganisms to be blocked, and eventually die or lose the ability to reproduce, thereby achieving the purpose of sterilization.

[0040] The steps to use are as follows:

[0041] 1) Chinese medicinal materials are fed into the feed port 21 and sent to the drying area 2 by the first conveyor belt 8 for drying to ensure that the water content is appropriate, which is beneficial to the subsequent grinding and irradiation sterilization process.

[0042] 2) The temperature of the Chinese medicinal materials after being dried by hot air is relatively high. Some Chinese medicinal materials need to be cooled down, and can be cooled down in the first cooling zone 3. If cooling down is not required, they can directly pass through the first cooling zone 3.

[0043] 3) At this time, the first tray 91 of the first lifting and feeding assembly 9 is at the lowest position. At the landing point of the first conveyor belt, the dried medicinal materials fall into the first tray 91. The first tray 91 drives the medicinal materials to move up to the top of the grinder. The rotating motor 95 drives the first tray 91 to flip over and pour the medicinal materials into the grinding area.

[0044] 4) The medicinal material enters from the trumpet-shaped feed port 43 and falls between the grinding rollers 44 that work together, and is ground into powder by the grinding rollers. The powder falls into the screen 45, and the grinding bin 41 vibrates under the drive of the vibrator 42 and is sieved. The sieved powder slides from the first unloading chute 46 to the tray of the second lifting and feeding assembly 10 under the action of the vibrator 42.

[0045] 5) The tray of the second lifting and feeding assembly 10 drives the powder to move upward and pour it into the vacuum sealing device; the powder is poured into the funnel of the feeding area, and quantitatively fed into the packaging bag from the bottom of the feeding funnel, and then the bag is sent to the vacuum sealing area for vacuum sealing, which helps to prevent microorganisms and impurities in the air from entering and ensure the effect of radiation sterilization.

[0046] 6) The sealed medicinal powder falls from the unloading area onto the second conveyor belt 11 and is sent to the second cooling area, so that the medicinal powder is pre-cooled in a low temperature environment to reduce the temperature of the medicinal powder so that it can maintain a low temperature during the irradiation process to avoid affecting the quality of the medicinal materials due to high temperature.

[0047] 7) The pre-cooled Chinese medicine powder is placed in a radiation sterilization device and subjected to irradiation sterilization treatment under an electron beam generator for 1-3 hours to achieve the purpose of sterilization.

[0048] 8) After irradiation sterilization, the powder is discharged from the feed chute and can be further tested and evaluated to test the Chinese medicinal materials to ensure that the sterilization effect meets the standards. This includes checking whether the physical and chemical properties of the medicinal materials have changed and whether the microorganisms have been effectively killed. Through the above steps, the Chinese medicinal materials can be effectively irradiated and sterilized to ensure the safety and effectiveness of the medicinal materials while maintaining the quality and stability of the medicinal materials.

[0049] The above is only a preferred embodiment of the present invention, and the protection scope of the present invention is not limited to the above embodiments. All technical solutions under the concept of the present invention belong to the protection scope of the present invention. It should be pointed out that for ordinary technicians in this technical field, some improvements and modifications without departing from the principle of the present invention should also be regarded as the protection scope of the present invention.

Claims

1. An integrated radiation sterilization machine for powder processing, including a chassis, characterized in that: The inside of the machine box is divided into a drying area, a grinding area, a bagging and sealing area, and an irradiation sterilization area; A feeding port is provided above the drying area, and a hot air drying component is provided on the top of the drying area; A first cooling zone is provided between the drying zone and the grinding zone, the first cooling zone is provided with a first cooling assembly, and a first conveyor belt is provided between the drying zone and the first cooling zone; A first lifting and feeding assembly is provided between the first cooling zone and the grinding zone, comprising a reversible tray and a tray lifting assembly; A grinder is provided in the grinding area, and a first material discharge chute is provided on the side of the grinder; A second lifting and feeding assembly is provided between the grinding area and the bagging and sealing area; a vacuum sealing device is provided in the bagging and sealing area; A second cooling zone is provided between the bagging and sealing zone and the irradiation sterilization zone, and the second cooling zone is provided with a second cooling assembly; A second conveyor belt is provided in the irradiation sterilization zone and the second cooling zone, an electron beam generator is provided in the irradiation sterilization zone, and a material discharge trough is provided on the side of the irradiation sterilization zone.

2. The integrated radiation sterilization machine for powder processing according to claim 1, characterized in that: The hot air drying component comprises a hot air disk, hot air outlets are evenly distributed on the hot air disk, and the hot air disk is connected to a hot air generator.

3. The integrated radiation sterilization machine for powder processing according to claim 1, characterized in that: A first partition is provided between the first cooling zone and the drying zone, and the first conveyor belt is located below the first partition.

4. The integrated radiation sterilization machine for powder processing according to claim 1, characterized in that: The first cooling component includes a cooling plate, cold air outlets are evenly distributed on the cooling plate, and the cooling plate is connected to a cold air fan.

5. The integrated radiation sterilization machine for powder processing according to claim 1, characterized in that: The grinder includes a grinding bin and a vibrator, the lower end of the grinding bin is mounted on the vibrator; a trumpet-shaped feed port is provided above the grinding bin, a group of grinding rollers working in cooperation with each other are provided below the feed port, and a screen is provided below the grinding rollers; the first discharge chute is connected to the bottom end of the grinding bin.

6. The integrated radiation sterilization machine for processing medicinal powder according to claim 1, characterized in that: The pallet lifting assembly includes a vertically arranged lifting guide rail, a lifting screw is provided in the middle of the lifting guide rail, and a lifting motor connected to the lifting screw is provided on the top of the lifting guide rail; a base is slidably installed on the lifting guide rail, a rotating motor is provided on the base, and the output shaft of the rotating motor is connected to the pallet to drive the pallet to flip.

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