Expandable biological sample library system and sample access method

Abstract

The invention relates to the technical field of biological sample libraries, in particular to an expandable biological sample library system and a sample access method.The expandable biological sample library system comprises at least one first unit, the first unit comprises a first functional area and a first storage area, and the first storage area is used for storing sample boxes; the at least one second unit comprises a second functional area and a second storage area, and the second storage area is used for storing a sample box; according to the sample library system, investment can be reduced and energy can be saved in the earlier stage of library construction, the first unit or the second unit can be freely added according to the requirements of a user in the later stage, equipment redundancy is avoided, the adaptability between different units is high, the sample box can be freely operated, the capacity expansion mode of the sample library is simple, the cost is low, and the samples are convenient, accurate and reliable to store and take; the storage and taking of a whole box or a single tube can be adapted, the energy consumption can be reduced by the independently arranged refrigerating system, and the safety of sample storage is ensured.

Description

Technical Field

[0001] The present invention relates to the technical field of biological sample libraries, and in particular to an expandable biological sample library system and a sample access method. Background Art

[0002] The storage capacity of existing biological sample libraries is fixed. In the early stage of library construction, the sample storage capacity is small, and storage devices with too large capacity waste space and energy. As the sample storage capacity increases during the development of the sample library, the capacity of the storage device needs to be increased. Capacity expansion generally adopts the method of adding storage devices, which is difficult to install.

[0003] Currently, there are two types of biobank storage devices: those with automation levels down to tubes and those with automation levels down to boxes. For users who require automation levels down to tubes when building biobanks, the purchase cost of multiple storage devices down to tubes is high and the functions are redundant. Sample libraries that choose to use a combination of two storage devices with different automation levels require the use of robots or manual transfer, which increases the cost of building the library. Summary of the invention

[0004] In view of the technical problems existing in the biological sample storage library in the prior art, the first aspect of the present invention proposes an expandable biological sample library system, including:

[0005] At least one first unit, the first unit comprising a first functional area and a first storage area, the first storage area being used to store the sample box;

[0006] at least one second unit, the second unit comprising a second functional area and a second storage area, the second storage area being used for storing the sample box;

[0007] Wherein, the first functional area is provided with two first transfer windows and one first pick-and-place window, and the second functional area is provided with two second transfer windows and one second pick-and-place window;

[0008] A plurality of the first units and a plurality of the second units are distributed along a linear direction to form a set of sample libraries, and a plurality of first access windows and a plurality of second transfer windows are distributed in a straight line direction;

[0009] The second functional area is configured to identify a sample box entering the second functional area and allow the sample box to be transferred between the second storage area, the two second transfer windows and the second access window;

[0010] The first functional area is configured to be able to identify the sample box entering the first functional area and the sample tube in the sample box, and to complete the transfer of the sample box between the first storage area, the two first transfer windows and the first access window;

[0011] The first functional area is configured to temporarily store at least two sample boxes entering the first functional area, and transfer the sample tubes between the two temporarily stored sample boxes.

[0012] Preferably, the first functional area and / or the first storage area stores at least one empty sample box.

[0013] Preferably, the second storage area stores at least one empty sample box.

[0014] Preferably, a grabbing component and a first turnover component are provided in the first functional area, and a first storage rack and a first grabbing manipulator are provided in the first storage area;

[0015] The grabbing component includes an XY drive mechanism, a first manipulator, a second manipulator, a temporary storage platform and a first identification device. The first turnover component is arranged on the temporary storage platform and partially covers the temporary storage platform. The first grabbing manipulator is used to transfer the sample box between the temporary storage platform and the first storage rack. The first manipulator is used to transfer the sample box between the temporary storage platform, the first turnover component and the first identification device. The first turnover component is used to transfer the sample box between two first transfer windows.

[0016] Preferably, a sample tube rack is provided on the temporary storage platform for temporarily storing sample tubes.

[0017] Preferably, the first functional area and the second functional area are separated by a first lattice door, and the first functional area and the second functional area have separate refrigeration systems.

[0018] Preferably, the second functional area is provided with a second turnover component and a second identification device, the second identification device identifies the sample box entering and exiting the second pick-up and placement window, and the second storage area is provided with a second storage rack and a second grabbing robot, the second grabbing robot is used to transfer the sample box between the second storage rack and the second turnover component.

[0019] Preferably, the second turnover component and the second storage rack are separated by a second lattice door, and the second functional area and the second storage area are provided with separate refrigeration systems.

[0020] Preferably, the second identification device is configured to identify the information of the sample tube entering the second pick-and-place window, and the second grasping robot grasps the unfull sample box from the second storage area and hands it to the second pick-and-place window for loading the sample tube identified by the second identification device.

[0021] The second aspect of the present invention proposes a technical solution, a sample storage and access method, using the above-mentioned expandable biological sample library system, including a sample storage method and a sample retrieval method;

[0022] The storage method comprises the following steps:

[0023] Step a1: the sample tube is delivered into any second access window, and the label information on the sample tube is identified by the second functional area;

[0024] Step a2: the system finds an unfilled sample box at a target position in any one of the first storage area or the second storage area, and identifies and transfers the sample box to the second access window through the first functional area and / or the second functional area;

[0025] Step a3: The user loads the sample tube into the sample box;

[0026] Step a4, the sample box carrying the target sample tube is transferred to the target position by the first functional area and / or the second functional area;

[0027] Wherein, the removal method comprises the following steps:

[0028] Step b1, the system determines that the corresponding sample box is at the target position according to the target sample tube information input by the user;

[0029] Step b2: the first functional area and / or the second functional area transfers the sample box at the target position and an empty sample box to the temporary storage platform;

[0030] Step b3, the second manipulator transfers the target sample tube to an empty sample box;

[0031] Step b4: The first robot transfers the sample box containing the target sample tube to the first pick-and-place window.

[0032] Compared with the prior art, the advantages of the present invention are:

[0033] The sample library system proposed in the present application can reduce investment and save energy in the early stage of library construction. In the later stage, the first unit or the second unit can be freely added according to the needs of users. There is no redundancy of equipment, and the adaptability between different units is high. The sample boxes can be operated freely. The sample library expansion method is simple and low-cost. The sample storage and access is convenient, accurate and reliable. It can adapt to the storage and access of whole boxes or single tubes. The separately set refrigeration system can reduce energy consumption and ensure the safety of sample storage. BRIEF DESCRIPTION OF THE DRAWINGS

[0034] The drawings are not intended to be drawn to scale. In the drawings, each identical or nearly identical component shown in various figures may be represented by the same reference numeral. For clarity, not every component is labeled in every figure. Embodiments of various aspects of the present invention will now be described by way of example and with reference to the accompanying drawings, in which:

[0035] Figure 1is a schematic structural diagram of an expandable biological sample library system shown in the present invention;

[0036] Figure 2 It is a schematic diagram of the connection between the first functional area and the second functional area shown in the present invention;

[0037] Figure 3 is a structural schematic diagram of the first unit shown in the present invention;

[0038] Figure 4 is a schematic diagram of the internal structure of the first unit shown in the present invention;

[0039] Figure 5 It is a structural schematic diagram of the grabbing component shown in the present invention;

[0040] Figure 6 is a structural schematic diagram of the second unit shown in the present invention;

[0041] Figure 7 It is a schematic diagram of the internal structure of the second unit shown in the present invention. DETAILED DESCRIPTION

[0042] In order to better understand the technical content of the present invention, specific embodiments are given and described as follows in conjunction with the accompanying drawings.

[0043] It should be understood that in order to ensure the accuracy of sample storage, sample libraries with a tube picking function have become mainstream, where the tube picking function refers to: the sample boxes used in biological sample libraries, the mainstream uses standard formats such as 0.75ml / 1ml / 2ml SBS sample boxes / tubes. Taking a 2ml SBS sample box with 48 2ml sample tubes as an example, if the storage device can only be a device that takes the sample box with all the sample tubes for storage (or access), we call it a device with automation to the box; if there is a structure in the storage device that can pick the sample tube out of the sample box, put it into another sample box, and then perform the storage and access action, we call this a device with automation to the tube. The function of transferring sample tubes is the tube picking function. The current sample library is basically a sample library built around an organization that includes a tube picking function. The later capacity expansion of this sample library involves problems such as the adaptation of the new storage structure and the decrease in tube picking efficiency.

[0044] Therefore, the present application aims to provide an expandable biological sample library system, which is equipped with two standardized units, one of which has a tube picking function, and the other has a box picking function. The two standardized units can be freely combined to form a biological sample library. The sample box can be freely transferred in any standardized unit, and the tube picking is completed by the standardized unit with the tube picking function. In the later stage, a number of standardized units with box picking or tube picking functions can be arbitrarily expanded according to needs.

[0045]

Scalable biobank system

[0046] The first aspect of the present invention provides an expandable biological sample library system, comprising at least one first unit 100 and at least one second unit 200, wherein a plurality of the first units 100 and a plurality of the second units 200 are distributed along a linear direction to form a set of sample libraries, and a plurality of the first units 100 and ... Figure 1 As shown, there are three groups of sample libraries, and the first unit 100 and the second unit 200 of each group of sample libraries are arranged linearly. For example, A represents the first unit 100 and B represents the second unit 200. Each group of sample libraries can be arranged in the following ways: ABBBBBB; ABBBBBA; BBBABBB, etc. The library builder can purchase any unit separately and can add any unit during use. When adding a unit, it does not affect the use of other unit storage areas.

[0047] The first unit 100 includes a first functional area 101 and a first storage area 102, and the first storage area 102 is used to store sample boxes; the second unit 200 includes a second functional area 201 and a second storage area 202, and the second storage area 202 is used to store sample boxes.

[0048] In a preferred embodiment, the first unit 100 and the second unit 200 should be configured to have the same outer dimensions, which is conducive to the combination of the first unit 100 and the second unit 200. The first functional area 101 has a tube-picking function, so its structure is more complicated and its volume is larger. The second functional area 201 does not have a tube-picking function and its volume is smaller than that of the first functional area 101. Therefore, the volume of the second storage area 202 is larger than that of the first storage area 102.

[0049] Combination Figure 3 and Figure 6 As shown, the first functional area 101 is provided with two first transfer windows 10b (only one is exposed in the figure, and the other is on the opposite side of the first transfer window 10b in the figure) and a first pick-and-place window 10a, and the second functional area 201 is provided with two second transfer windows 20b and a second pick-and-place window 20a.

[0050] It should be understood that combined Figure 2 As shown, the first access window 10a and the second access window 20a should face the aisle side where the equipment is placed, which is convenient for users to access and place samples from the first access window 10a or the second access window 20a, and the two first transfer windows 10b and the two second transfer windows 20b are preferably distributed in a straight line direction, so that the sample box can be transferred between any two first units 100 and / or second units 200 through the first transfer window 10b or the second transfer window 20b.

[0051] In this way, the transmission structure provided in the first unit 100 and the second unit 200 can be as simple as possible, completing only linear transmission, while also facilitating the expansion and adaptation of subsequent newly added units.

[0052] In a specific embodiment, if the user's requirement is to take out a sample tube, and since only the first unit 100 has a tube picking function, the user can only take the tube from the first transfer window 10b. If the target sample tube is in the second unit 200, the sample box containing the target sample tube in the second unit 200 needs to be transferred to the first unit 100 through the transfer window, and then the first unit 100 picks the tube and sends it to the first pick-up and placement window 10a.

[0053] Furthermore, the main purpose of the second functional area 201 is to transfer the sample box loaded with sample tubes required by the user in the second storage area 202 to the first unit 100. Therefore, the second functional area 201 is configured to identify the sample box entering the second functional area 201 and enable it to be transferred between the second storage area 202, two second transfer windows 20b and a second pick-and-place window 20a.

[0054] Specifically, when the target sample box is in the second storage area 202 of this unit, the second functional area 201 transfers the target sample box to a second transfer window 20b of the first unit 100 that issues the request among the two second transfer windows 20b; when the target sample box only temporarily passes through the second functional area 201, the second functional area 201 is responsible for transporting the target sample box from the first second transfer window 20b on the transfer path to the second second transfer window 20b.

[0055] In other embodiments, if the user requests a whole box of sample tubes, or requests to store a single sample tube, the second functional area 201 can also transfer the sample box from the second storage area 202 to the second access window 20a, and fill the sample box back to the second storage area 202 from the second access window 20a.

[0056] Furthermore, the first functional area 101 has more functions than the second functional area 201, and it has a tube picking function. Therefore, the first functional area 101 is configured to be able to identify the sample box entering the first functional area 101 and the sample tube in the sample box, and can complete the transfer of the sample box between the first storage area 102, the two first transfer windows 10b and the first placement window 10a.

[0057] Furthermore, in the box picking function, the sample library cannot hand over a single sample tube to the user in the form of a tube, but rather hands it over to the user in the form of a sample box as a carrier. Therefore, the first functional area 101 is configured to temporarily store at least two sample boxes entering the first functional area 101, and transfer the sample tube between the two temporarily stored sample boxes.

[0058] In this way, after the first functional area 101 selects the tube, it is necessary to open the sample box containing the target sample tube, take out the target sample tube, and load it into the empty sample box. The user takes out the sample box containing only the target sample tube.

[0059] Specifically, when the target sample tube required by the user is in the first storage area 102, the first functional area 101 is responsible for picking up the sample box containing the target sample tube in the first storage area 102 and loading it into a new sample box and placing it in the first access window 10a; when the sample tube is in the second storage area 202, the first functional area 101 is responsible for transporting the sample box containing the target sample tube from the second storage area 202 to the first transfer window 10b and loading it into a new sample box and placing it in the first access window 10a; when the user stores the sample tube, the sample box can be transferred from the first access window 10a to the first transfer window 10b (stored in the second storage area 202) or to the first storage area 102 (stored in the first storage area 102).

[0060] Furthermore, in order to satisfy the requirement of the first unit 100 to complete the storage and removal of a single tube, at least one empty sample box is stored in the first functional area 101 and / or the first storage area 102. The sample box is used to transfer the target sample tube.

[0061] Furthermore, in order to satisfy the second unit 200 to complete the storage of a single tube, at least one empty sample box is stored in the second storage area 202. The empty sample box is used to store the single tube of the unit, and after storage, an unfilled sample box is formed. When an unfilled sample box does not exist in the second unit 200, an unfilled sample box is requested from other second units 200. If an unfilled sample box does not exist in any second unit 200, the second unit 200 cannot complete the single tube storage function.

[0062] Combination Figure 4 As shown, in an optional embodiment, a grabbing component 13 and a first turnover component 14 are provided in the first functional area 101, and a first storage rack 11 and a first grabbing robot are provided in the first storage area 102.

[0063] Among them, the first grasping robot is used to transfer the sample box stored in the first storage rack 11 to the handover position, and the grasping component 13 is responsible for transferring the sample box at the handover position to the first turnover component 14, or transferring from the first turnover component 14 to the handover position, and the first grasping robot then transfers the sample box from the handover position to the first storage rack 11 to complete the picking and placing process.

[0064] like Figure 5As shown, the grabbing component 13 includes an XY drive mechanism 131, a first manipulator 132, a second manipulator 133, a temporary storage platform 134 and a first identification device 135. The first turnover component 14 is arranged on the temporary storage platform 134 and partially covers the temporary storage platform 134. The first grabbing manipulator is used to transfer the sample box between the temporary storage platform 134 and the first storage rack 11. The first manipulator 132 is used to transfer the sample box between the temporary storage platform 134, the first turnover component 14 and the first identification device 135. The first turnover component 14 is used to transfer the sample box between the two first transfer windows 10b.

[0065] Among them, the XY driving mechanism 131 includes two groups of cross-shaped linear driving mechanisms, such as a screw driving structure, which can drive the first manipulator 132 and the second manipulator 133 installed on the XY driving mechanism 131 to move in the XY plane. The first manipulator 132 and the second manipulator 133 can drive the clamping structure at the bottom to move along the Z axis. The difference between the first manipulator 132 and the second manipulator 133 lies in the different clamping structures. The first manipulator 132 can clamp the sample box, and the second manipulator 133 can clamp the sample tube. The XY driving mechanism 131 can drive the first manipulator 132 and the second manipulator 133 to move to any position of the temporary storage platform 134 to realize the transfer of the sample box and the sample tube.

[0066] The first recognition device 135 is disposed on the temporary storage platform 134. The first recognition device 135 is composed of two parts: a barcode scanner and a visual camera, and can complete the entry of sample box code information and the code information of a whole box of sample tubes.

[0067] Preferably, a sample tube rack is provided on the temporary storage platform 134 for temporarily storing sample tubes.

[0068] Combination Figure 7 As shown, the second functional area 201 is provided with a second turnover component 23 and a second identification device 24, the second identification device 24 identifies the sample box entering and exiting the second pick-up and placement window 20a, and the second storage area 202 is provided with a second storage rack 21 and a second grasping robot, and the second grasping robot is used to transfer the sample box between the second storage rack 21 and the second turnover component 23.

[0069] Optionally, the second circulating component 23 and the first circulating component 14 both include a conveyor belt, the conveying direction of the conveyor belt is toward the direction of the circulation window, and the first grabbing manipulator or the second grabbing manipulator can put the sample box on the conveyor belt, or put it from the conveyor belt to the storage rack. A batch code scanning device is provided on one side of the conveyor belt to identify the code information of the sample boxes passing through the conveyor belt.

[0070] In the above-mentioned embodiment, the code scanning device is used to identify the QR code or radio frequency tag of the sample box or sample tube, and the specific position and sample information of the sample box or sample tube are identified by scanning the code. The controller is responsible for coordinating the actions of the grabbing components or turnover components of each functional area to transfer the corresponding sample box or sample tube to the predetermined position.

[0071] Preferably, the first functional area 101 and the second functional area 201 are separated by a first lattice door 12, and the first functional area 101 and the second functional area 201 have separate refrigeration systems. The second turnover component 23 and the second storage rack 21 are separated by a second lattice door 22, and the second functional area 201 and the second storage area 202 are provided with separate refrigeration systems. The first lattice door 12 and the second lattice door 22 are automatic doors.

[0072] In this way, the functional area and the storage area have separate refrigeration effects. Compared with the large-capacity, low-storage-rate, unified refrigeration technology in the prior art, it can greatly reduce energy consumption and meet the low-temperature storage conditions of samples.

[0073] Furthermore, the second identification device 24 is configured to identify the sample tube information entering the second pick-up and placement window 20a, and the second grasping robot grasps the unfilled sample box from the second storage area 202 and hands it to the second pick-up and placement window 20a for loading the sample tube identified by the second identification device 24.

[0074] Optionally, the second identification device 24 is composed of two parts: a barcode scanner and a visual camera, which can complete the entry of sample box code information and the code information of a whole box of sample tubes.

[0075]

Sample Access Method

[0076] The second aspect of the present invention proposes a technical solution, a sample storage and access method, using the above-mentioned expandable biological sample library system, including a sample storage method and a sample retrieval method;

[0077] The storage method comprises the following steps:

[0078] Step a1: the sample tube is passed into any second access window 20a, and the label information on the sample tube is identified by the second functional area 201;

[0079] Step a2: the system finds an unfilled sample box at a target position in any one of the first storage area 102 or the second storage area 202, and identifies and transfers the unfilled sample box to the second access window 20a through the first functional area 101 and / or the second functional area 201;

[0080] Step a3: The user loads the sample tube into the sample box;

[0081] Step a4: the sample box carrying the target sample tube is transferred to the target position by the first functional area 101 and / or the second functional area 201;

[0082] Wherein, the removal method comprises the following steps:

[0083] Step b1, the system determines that the corresponding sample box is at the target position according to the target sample tube information input by the user;

[0084] Step b2: the first functional area 101 and / or the second functional area 201 transfers the sample box at the target position and an empty sample box to the temporary storage platform 134;

[0085] Step b3, the second manipulator 133 transfers the target sample tube to an empty sample box;

[0086] Step b4: The first robot 132 transfers the sample box carrying the target sample tube to the first placement window 10a.

[0087] In a specific embodiment, the pipe selection process is as follows:

[0088] The samples stored or taken out are determined according to the order in which the tasks are issued. No matter which unit the target sample is in, it will be sent to the nearest first unit 100 through the sample box conveying line to complete the tube picking. A certain number of empty sample boxes will be stored in the first unit 100 so that the target sample can be placed in the sample box and then sent out of the device or stored in the device using the sample box as a carrier.

[0089] The single tube convenient storage process is as follows:

[0090] Perform the following operations on the second unit 200 to complete the convenient deposit function:

[0091] Assume that a sample box A containing 47 tubes is stored in the second storage area 202 of the second unit 200, and one tube position of the sample box A is vacant. The operator wants to store one sample tube a and selects the convenient storage;

[0092] To start the convenient storage, the second grabbing robot takes out the sample box A from the second storage area 202 and places it on the batch code scanning device in the second functional area 201 to scan the code and confirm the sample information;

[0093] When the sample information is confirmed to be correct (confirmed to have an empty tube position), the transmission line of the second functional area 201 transmits the sample box A out of the second access window 20a;

[0094] The operator places the sample tube a at the camera next to the second access window 20a to scan the QR code on the bottom of the sample tube a to confirm the information;

[0095] Confirm completion, put sample tube a into the empty space in sample box A, click "Put in Complete", and the transmission line of the second functional area 201 is retracted with the sample box;

[0096] The full sample box A is then confirmed to have correct sample information by the batch code scanning device in the second functional area 201 and stored in the second storage area 202, thus completing the convenient storage.

[0097] In combination with the above embodiments, the sample library system proposed in the present application can reduce investment and save energy in the early stage of library construction. In the later stage, the first unit or the second unit can be freely added according to the needs of users. There is no redundancy of equipment, and the adaptability between different units is high. The sample boxes can be operated freely. The sample library expansion method is simple and low-cost. The sample storage and access is convenient, accurate and reliable. It can adapt to the storage and access of whole boxes or single tubes. The separately set refrigeration system can reduce energy consumption and ensure the safety of sample storage.

[0098] Although the present invention has been disclosed as above with preferred embodiments, it is not intended to limit the present invention. A person with ordinary knowledge in the technical field to which the present invention belongs may make various changes and modifications without departing from the spirit and scope of the present invention. Therefore, the protection scope of the present invention shall be determined by the definition of the claims.

Claims

1. A scalable biological sample library system, characterized in that: include: At least one first unit (100), the first unit (100) comprising a first functional area (101) and a first storage area (102), the first storage area (102) being used for storing a sample box; At least one second unit (200), the second unit comprising a second functional area (201) and a second storage area (202), the second storage area (202) being used for storing a sample box; The first functional area (101) is provided with two first transfer windows (10b) and one first pick-and-place window (10a), and the second functional area (201) is provided with two second transfer windows (20b) and one second pick-and-place window (20a); A plurality of the first units (100) and a plurality of the second units (200) are distributed along a linear direction to form a set of sample libraries, and a plurality of first access windows (10a) and a plurality of second transfer windows (20b) are distributed in a linear direction; The second functional area (201) is configured to identify a sample box entering the second functional area (201) and enable the sample box to be transferred between the second storage area (202), the two second transfer windows (20b) and the one second access window (20a); The first functional area (101) is configured to be able to identify a sample box entering the first functional area (101) and a sample tube in the sample box, and to complete the transfer of the sample box between the first storage area (102), the two first transfer windows (10b) and the first access window (10a); The first functional area (101) is configured to temporarily store at least two sample boxes entering the first functional area (101), and to transfer sample tubes between the two temporarily stored sample boxes.

2. The scalable biological sample library system according to claim 1, characterized in that: The first functional area (101) and / or the first storage area (102) stores at least one empty sample box.

3. The scalable biological sample library system according to claim 1, characterized in that: The second storage area (202) stores at least one empty sample box.

4. The scalable biological sample library system according to claim 1, characterized in that: The first functional area (101) is provided with a grasping component (13) and a first turnover component (14), and the first storage area (102) is provided with a first storage rack (11) and a first grasping manipulator; The grasping component (13) comprises an XY driving mechanism (131), a first manipulator (132), a second manipulator (133), a temporary storage platform (134) and a first identification device (135); the first turnover component (14) is arranged on the temporary storage platform (134) and partially covers the temporary storage platform (134); the first grasping manipulator is used to transfer the sample box between the temporary storage platform (134) and the first storage rack (11); the first manipulator (132) is used to transfer the sample box between the temporary storage platform (134), the first turnover component (14) and the first identification device (135); and the first turnover component (14) is used to transfer the sample box between the two first transfer windows (10b).

5. The scalable biological sample library system according to claim 4, characterized in that: The temporary storage platform (134) is provided with a sample tube rack for temporarily storing sample tubes.

6. The scalable biological sample library system according to claim 4, characterized in that: The first functional area (101) and the second functional area (201) are separated by a first lattice door (12), and the first functional area (101) and the second functional area (201) have independent refrigeration systems.

7. The scalable biological sample library system according to claim 1, characterized in that: The second functional area (201) is provided with a second circulating component (23) and a second identification device (24), the second identification device (24) identifies the sample box entering and exiting the second loading and unloading window (20a), and the second storage area (202) is provided with a second storage rack (21) and a second grasping robot, the second grasping robot is used to transfer the sample box between the second storage rack (21) and the second circulating component (23).

8. The scalable biological sample library system according to claim 7, characterized in that: The second circulation component (23) and the second storage rack (21) are separated by a second lattice door (22), and the second functional area (201) and the second storage area (202) are provided with separate refrigeration systems.

9. The scalable biological sample library system according to claim 7, characterized in that: The second identification device (24) is configured to identify the information of the sample tube entering the second pick-up and placement window (20a), and a second grasping robot grasps an unfilled sample box from the second storage area (202) and hands it to the second pick-up and placement window (20a) for loading the sample tube identified by the second identification device (24).

10. A sample access method, characterized in that: Using the expandable biological sample library system described in any one of claims 1 to 8, including a sample storage method and a sample retrieval method; The storage method comprises the following steps: Step a1, the sample tube is passed into any second access window (20a), and the label information on the sample tube is identified by the second functional area (201); Step a2: the system finds an unfilled sample box at a target position in any one of the first storage area (102) or the second storage area (202), and identifies and transfers the sample box to the second access window (20a) through the first functional area (101) and / or the second functional area (201); Step a3: The user loads the sample tube into the sample box; Step a4: the sample box carrying the target sample tube is transferred to the target position by the first functional area (101) and / or the second functional area (201); Wherein, the removal method comprises the following steps: Step b1, the system determines that the corresponding sample box is at the target position according to the target sample tube information input by the user; Step b2: the first functional area (101) and / or the second functional area (201) transfers the sample box at the target position and an empty sample box to the temporary storage platform (134); Step b3, the second manipulator (133) transfers the target sample tube to an empty sample box; Step b4: The first robot (132) transfers the sample box carrying the target sample tube to the first loading and unloading window (10a).

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