Sheet driver and medicine dispensing device

Abstract

The invention discloses a tablet driver and a medicine dispensing device, the tablet driver comprises a driving part, a shaft part, a shaft hub and an elastic arm, and the shaft part extends perpendicular to the driving part and defines a rotation axis; the shaft hub is arranged on one side of the driving part and can rotate around the shaft part, and the surface of the shaft hub is configured to be used for receiving a target piece; the elastic arm extends from the periphery of the shaft part to the inner wall of the shaft hub, and the elastic arm is connected with the shaft hub through a quick connection structure; when the shaft hub rotates relative to the shaft part, the elastic arms can deflect clockwise / anticlockwise, and therefore tightness compensation is provided. According to the sheet driver and the medicine distribution device, due to the compensation design of the sheet driver, the medicine carrier can be subjected to stable tension and is uniformly indexed, and therefore it is guaranteed that medicine can be accurately in place. The chip driver is simple in structure and convenient to assemble, and the effects of reducing cost and increasing efficiency are achieved in the device assembling process.

Description

[0001] This application is a divisional application of Chinese patent application CN202410521041.9, filed on April 25, 2024, entitled “A tablet driver and drug dispensing device”. Technical Field

[0002] The present invention relates to the technical field of medical devices, and in particular to a tablet driver and a medicine dispensing device. Background Art

[0003] The use of inhalation devices in the administration of medicaments, for example in bronchodilatory therapy, is well known. Such devices generally comprise a body or housing in which a medicament carrier is disposed. Known inhalation devices include those in which the medicament carrier is a blister strip containing a number of discrete doses of a powdered medicament. Such devices generally comprise a mechanism for accessing these doses, generally including a puncturing device or a device for peeling a cover sheet from a base sheet so that the powdered medicament can be accessed and inhaled. Such mechanisms may also be used to dispense tablet-type medicaments, wherein peeling a cover sheet from a base sheet exposes the tablet for removal and subsequent consumption.

[0004] The applicant has learned that such devices usually achieve the drug delivery function by rotating the outer cover to activate its internal mechanism. At the same time, the applicant has also learned such potential problems: the design expects that during the opening of the outer cover, the drug carrier can be subjected to a stable pulling force and evenly divided, and after use, the outer cover can be automatically closed instead of being reset by hand. Summary of the invention

[0005] The object of the present invention is to provide a sheet driver and a drug dispensing device, which are at least used to solve the problem that the drug carrier cannot be evenly divided due to unstable pulling force, so that the drug can be accurately placed.

[0006] A chip driver, comprising: Drive unit; A shaft portion extending perpendicularly to the driving portion and defining a rotation axis; a hub, disposed at one side of the driving portion and capable of rotating around the shaft portion, wherein a surface of the hub is configured to receive a target piece; An elastic arm extends from the outer periphery of the shaft portion toward the inner wall of the shaft hub, and the elastic arm is connected to the shaft hub through a quick-connect structure; When the hub rotates relative to the shaft portion, the elastic arm can deflect clockwise or counterclockwise, thereby providing tension compensation.

[0007] In some embodiments, the driving part is a driving wheel or a driving gear.

[0008] In some embodiments, the shaft portion is integrally formed with the driving portion and / or the elastic arm.

[0009] In some embodiments, a central hole extending to the driving portion is disposed in the shaft portion.

[0010] In some embodiments, an assembly hole is provided at one end of the hub away from the driving portion, and the hub is sleeved on the shaft portion through the assembly hole.

[0011] In some embodiments, a flange is provided on the outer periphery of the shaft portion, the outer diameter of the flange is larger than the hole diameter of the assembly hole, and the distance from the flange to the driving portion is greater than or equal to the distance from the assembly hole to the driving portion.

[0012] In some embodiments, a boss is provided on one side of the driving portion close to the hub; a plurality of vertical ribs are provided at intervals on the inner wall of the hub, and the vertical ribs are provided with corners riding on the boss.

[0013] In some embodiments, the hub has a groove at its edge to form a hook portion, and the hook portion is configured to receive the front end portion of the target sheet.

[0014] In some embodiments, the outer circumference of the shaft hub is provided with at least one section; and / or, the surface of the shaft hub is provided with scratches or a coating.

[0015] In some embodiments, an observation port is provided on the driving portion, and the position of the observation port is directly opposite to the position of the quick-connect structure.

[0016] In some embodiments, the quick-connect structure includes a fixing member disposed in the hub and a counterpart member disposed on the elastic arm; wherein the counterpart member is cooperatively connected with the fixing member.

[0017] In some embodiments, the fixing member is a cross rib integrally formed on the inner top of the hub, and the opposing member is a jacket, which is detachably mounted on the cross rib.

[0018] A drug dispensing device is provided with at least one drug carrier having a plurality of pouches, wherein the pouches are defined between a base sheet and a cover sheet which are attached to each other and can be separated from each other under the action of a pulling force, the drug dispensing device comprising: a receiving station for receiving drug powder from the sachets of the drug carrier; a dispensing mechanism configured to open the pouches of the drug carrier one by one and deliver them to the receiving station, while respectively rolling up the peeled base sheet and the cover sheet, wherein the dispensing mechanism includes the above-mentioned sheet driver; An outlet is connected to the receiving station for a user to absorb at least one drug powder each time for treatment.

[0019] In some embodiments, the dispensing mechanism further comprises an indexing wheel having a recess for receiving the bladder; The indexing wheel is in driving connection with the sheet driver, and the groove can deliver the capsules of the drug carrier to the receiving station one by one as the indexing wheel rotates.

[0020] In some embodiments, the drug dispensing device further comprises a flip cover that is continuously movable from a first position of the device through a second position to a third position and is mechanically coupled to the sheet driver; Wherein, when in the first position, the flip cover completely covers the outlet; When the flap moves from the first position to the second position, the flap at least partially exposes the outlet, but the flap movement does not actuate the sheet driver; From the second position to the third position, the flip cover completely exposes the outlet, and its movement actuates the sheet driver.

[0021] Compared with the prior art, the beneficial effects of the present invention include at least: 1. Through the compensation design of the sheet driver, the drug carrier can be subjected to stable tension and evenly divided, thus ensuring that the drug can be accurately placed.

[0022] 2. The chip driver has a simple structure and is easy to assemble, which reduces costs and increases efficiency during device assembly.

[0023] 3. The flip cover has the function of locking in place and automatic reset, which is convenient for users.

[0024] 4. The twisting piece makes it difficult for the flip cover to be opened by accident, and can also promote the full reset of the flip cover, thereby reducing the possibility of accidentally touching the outlet and causing contamination.

[0025] 5. The idling design of the ratchet assembly and the torsion member of the locking mechanism both have the function of preventing misoperation, which can avoid ineffective release of drugs.

[0026] 6. The sliding unit ensures that the ratchet assembly is always in the reference position after each actuation, thereby ensuring that the capsule on the drug carrier can be accurately positioned and improving the reliability of drug administration.

[0027] 7. The flip-cover linkage distribution mechanism simplifies the device structure and facilitates user actuation and control. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] Figure 1 It is a schematic diagram of the structure of the drug carrier used in the drug dispensing device of the present invention.

[0029] Figure 2 It is a schematic diagram of the structure of the medicine dispensing device of the present invention when it is in the first position.

[0030] Figure 3 It is a schematic diagram of the structure of the medicine dispensing device of the present invention when it is in the second position.

[0031] Figure 4 It is a schematic structural diagram of the medicine dispensing device of the present invention when it is in the third position.

[0032] Figure 5 It is a schematic structural diagram of the dispenser housing of the medicine dispensing device of the present invention.

[0033] Figure 6 It is a schematic diagram of the internal structure of the medicine dispensing device of the present invention after the second shell is hidden.

[0034] Figure 7 It is a schematic diagram of the coordination between the receiving station, the dispensing mechanism and the outlet of the medicine dispensing device of the present invention.

[0035] Figure 8 Schematic diagram of the automatic rebound structure of the cover of the medicine dispensing device of the present invention.

[0036] Fig. 9 It is a partial enlarged view of the inner side of the first housing of the drug dispensing device of the present invention.

[0037] Fig.10 It is a schematic structural diagram of the flip cover of the medicine dispensing device of the present invention.

[0038] Fig.11 It is a front structural schematic diagram of the dispensing mechanism of the medicine dispensing device of the present invention.

[0039] Fig.12 It is a schematic diagram of the back structure of the dispensing mechanism of the medicine dispensing device of the present invention.

[0040] Fig.13 is a schematic diagram of the ratchet assembly of the drug dispensing device of the present invention when it is in the first position.

[0041] Fig.14 is a schematic diagram of the ratchet assembly of the drug dispensing device of the present invention when it is in the second position.

[0042] Fig.15 is a schematic diagram of the ratchet assembly of the drug dispensing device of the present invention when it is in the third position.

[0043] Fig.16a It is a schematic diagram when the ratchet assembly is in the reference position.

[0044] Fig.16b It is a schematic diagram of the ratchet assembly deviating from the reference position.

[0045] Fig.17 It is a schematic diagram of the structure of the ratchet assembly of the medicine dispensing device of the present invention.

[0046] Fig.18 yes Fig.17 Section view along AA.

[0047] Fig.19 It is a schematic structural diagram of the first wheel of the ratchet assembly of the medicine dispensing device of the present invention.

[0048] Fig. 20 It is a schematic structural diagram of the second wheel of the ratchet assembly of the medicine dispensing device of the present invention.

[0049] Fig.21 It is a schematic diagram of the structure of the sheet driver of the medicine dispensing device of the present invention.

[0050] Fig. 22 It is a schematic structural diagram of the sheet driver of the medicine dispensing device of the present invention from another viewing angle.

[0051] Fig.23 It is a schematic diagram of the connection structure of the shaft portion, the driving portion and the elastic arm of the sheet driver of the medicine dispensing device of the present invention.

[0052] Fig.24 It is a schematic structural diagram of the hub of the tablet driver of the medicine dispensing device of the present invention.

[0053] Fig.25 It is a schematic diagram of the transmission connection between the substrate winding reel and the counter of the medicine dispensing device of the present invention.

[0054] In the figure: 1, distributor housing; 11, first housing; 12, second housing; 13, air grille; 14, convex portion; 141, opening; 142, first retaining groove; 143, assembly cavity; 2. Export; 3. Flip cover; 31. Rotating part; 311. Interface; 312. Guide groove; 313. Second retaining groove; 32. Anti-slip pattern; 4. distribution mechanism; 41. mounting frame; 411. main shaft; 42. ratchet assembly; 421. first wheel; 4211. ratchet; 42111. first guide section; 42112. friction fitting section; 42113. inner tooth structure; 42114. second guide section; 42115. outer tooth structure; 4212. main gear; 4213. mounting hole; 4214. recessed area; 422. second wheel; 4221. ratchet arm; 4222. positioning protrusion; 4223. convex key; 423. sliding block unit; 4231. sliding groove; 4232. stopper; 43. transmission assembly; 431. indexing wheel; 4311. groove; 44. stripping assembly; 441. sheet driver; 4411. driving unit; 44 111, observation port; 44112, boss; 4412, shaft; 44121, center hole; 44122, flange; 4413, hub; 44131, assembly hole; 44132, groove; 44133, hook; 44134, vertical rib; 44135, fixing piece; 4414, elastic arm; 44141, hand piece; 442, substrate winding reel; 45, retaining plate; 451, elastic hook; 452, arc groove; 5. Receiving station; 51. Receiving hole; 6. Locking mechanism; 61. Torsion member; 62. Lock tongue; 63. Button; 7. Counter; 8. Drug carrier; 81. Capsule; 82. Base sheet; 83. Cover sheet. DETAILED DESCRIPTION

[0055] Example embodiments will now be described more fully with reference to the accompanying drawings. However, example embodiments can be implemented in a variety of forms and should not be construed as limited to the embodiments set forth herein; rather, these embodiments are provided to make the present invention more comprehensive and complete and to fully convey the concepts of example embodiments to those skilled in the art. The same reference numerals in the figures represent the same or similar structures, and thus their repeated description will be omitted.

[0056] The words expressing positions and directions described in the present invention are all explained with reference to the accompanying drawings as examples, but they can be changed as needed, and all such changes are included in the protection scope of the present invention.

[0057] The present application discloses a drug dispensing device, which is equipped with at least one drug carrier 8 having a plurality of pouches 81. Figure 1 As shown, the drug carrier 8 is in the form of a strip and is presented in a rolled form, and the pouches 81 are extended in length and in the transverse direction relative to the drug carrier 8, so that a large number of pouches 81 can be spaced evenly along a given length to supply drugs.

[0058] The medicine carrier 8 comprises a base sheet 82 and a cover sheet 83. A blister is formed on the base sheet 82, and the pouch 81 is formed after being attached to the cover sheet 83, that is, the pouch 81 is defined between the base sheet 82 and the cover sheet 83 attached to each other. The base sheet 82 and the cover sheet 83 can be appropriately adhered to each other by heat sealing, but except for the front end portion of the base sheet 82 and the front end portion of the cover sheet 83, this makes the front end portion of the medicine carrier 8 separate from each other, which is conducive to the separation of the two from each other under the action of tension, thereby opening the pouch 81 on the medicine carrier 8.

[0059] The pouches 81 on each dose carrier 8 have the same type and / or contain the same dosage value (e.g., mass or volume) of drug powder, or in other embodiments, the pouches 81 on each dose carrier 8 also have different types and / or contain different dosage values ​​of drug powder.

[0060] join Figures 2 to 7 As shown, the drug dispensing device comprises a dispenser housing 1 , an outlet 2 , a flip cover 3 and a dispensing mechanism 4 .

[0061] The dispenser housing 1 may be in any suitable shape or form so as to accommodate other parts or mechanisms of the device, such as the receiving station 5, the dispensing mechanism 4, and the like.

[0062] like Figure 5 As can be seen, in a specific embodiment, the dispenser housing 1 includes a first shell 11 and a second shell 12, which can be symmetrically distributed on the left and right and cannot be disassembled after being connected. For example, the first shell 11 and the second shell 12 can be connected to form the dispenser housing 1 by hot melting, snap fastening or other connection methods, so that the device becomes a disposable consumable, thereby improving safety of use.

[0063] The outlet 2 is arranged on the dispenser housing 1. For example, the outlet 2 can be fixed on the top of the dispenser housing 1 by snapping. The outlet 2 has a raised fitting portion which is configured in a relatively flat elliptical form to fit the lips of the human body.

[0064] In addition, the outlet 2 is connected to the receiving station 5. Figure 7 As shown, the receiving station 5 is arranged in the dispenser housing 1, which can be detachably connected to the dispensing mechanism 4 as a whole, and the receiving station 5 is provided with at least one receiving hole 51 at the end away from the outlet 2, and the receiving hole 51 can be docked with the dividing wheel 431 in the dispensing mechanism 4, and the dispensing mechanism 4 is manipulated to administer the drug, so that the user can absorb at least one drug powder each time for treatment.

[0065] Further, Figures 3 to 5It is shown that the dispenser housing 1 is provided with an air grille 13 communicating with the receiving station 5 , and the air grille 13 allows air to enter the receiving station 5 , thereby providing auxiliary airflow to break up the drug powder when the device is used, so that it can be fully absorbed by the user.

[0066] Still see Figures 2 to 4 As shown, the flip cover 3 is arranged on the dispenser housing 1, and the two are rotatably connected, and the flip cover 3 can be continuously moved from the first position of the device to the second position to the third position. The user can flexibly control the opening and closing of the outlet 2 by controlling the movement of the flip cover 3, and selectively link the dispensing mechanism 4 to perform the drug administration action, thereby improving the convenience of operation. The linkage relationship between the flip cover 3 and the dispensing mechanism 4 is described in detail below.

[0067] It should be noted that, during the above movement process, the first position corresponds to the initial position, at which the flip cover 3 can cover and protect the outlet 2. The second position is a transition position. Before reaching the second position, the outlet 2 is at least partially exposed, and the dispensing mechanism 4 in the device is not activated. On the one hand, this design hopes that the user will not activate the dispensing mechanism 4 to cause drug waste when cleaning the outlet 2. On the other hand, it provides an invalid movement path to avoid the dispensing mechanism 4 directly administering drugs due to misoperation. The third position corresponds to the terminal position, at which the outlet 2 is completely exposed, and the dispensing mechanism 4 opens the pouch 81 and delivers it to the receiving hole 51 of the receiving station 5, indicating that the device is ready for use.

[0068] See also Figures 8 to 10 As shown, in a preferred embodiment, a locking mechanism 6 is provided between the flip cover 3 and the dispenser housing 1, thereby forming an automatic cover rebound structure. In the automatic cover rebound structure, when the flip cover 3 moves from the first position of the device to the third position, the locking mechanism 6 can limit it in the third position, and automatically reset it to the first position after being triggered.

[0069] The locking mechanism 6 includes a torsion piece 61, a lock tongue 62 and a button 63. The torsion piece 61 is connected to the dispenser housing 1 and the flip cover 3 respectively, and can be twisted around the rotation axis of the flip cover 3. For example, the torsion piece 61 can be a torsion spring, which provides the required torque for the flip cover 3 to reset. The lock tongue 62 is arranged on the rotating part 31 of the flip cover 3. For example, the lock tongue 62 can be integrally formed on the rotating part 31. The lock tongue 62 is roughly hook-shaped, which is more conducive to elastic deformation in the direction perpendicular to the flip cover 3. The button 63 is arranged on the convex part 14 of the dispenser housing 1. The convex part 14 is formed to protrude outward from the middle of the surface of the dispenser housing 1, and the convex part 14 is provided with an opening 141 opposite to the button 63.

[0070] In the above-mentioned automatic rebound structure of the cover, when the flip cover 3 moves to the third position of the device, the locking tongue 62 engages with the opening 141 to limit the flip cover 3. Compared with the existing cover structure, the flip cover 3 of the present application will not move when the user uses the device, thereby avoiding accidental movement that causes changes in drug dosage and affects treatment, while reducing the impact on the patency of the outlet 2 and the engagement with the lip. In addition, after the user triggers the button 63, that is, after the pressing operation, the locking tongue 62 can be separated from the opening 141, and the flip cover 3 is reset to the first position under the drive of the twisting member 61, thereby replacing the existing cover structure to manually push the flip cover 3 to reset, which is simpler and more efficient in operation.

[0071] It can be understood that when the flip cover 3 is moved from the first position of the device to the second position or the third position, the user needs to overcome the torque of the twisting member 61 to achieve this. This means that when the flip cover 3 is in the first position, it is actually restricted by the twisting member 61. However, it is precisely this restriction that makes the twisting member 61 have a better anti-misoperation function, thereby avoiding problems caused by the device being opened against the user's subjective will, such as the outlet 2 being contaminated, the dispensing mechanism 4 administering the drug, etc.

[0072] In the cover automatic rebound structure, Figures 2 to 4 Both show that the flip cover 3 is provided with anti-slip grooves 32 at least at the operating end (the end of the flip cover 3 close to the user's thumb) to increase friction and facilitate the user's cover opening operation.

[0073] See also Figure 6 and Fig.10 As shown, the rotating part 31 of the flip cover 3 is provided with an interface 311, which is used to mechanically connect the target component, for example, it can be connected with the ratchet assembly 42 of the dispensing mechanism 4, thereby actuating the dispensing mechanism 4 to perform the drug dispensing function through the flip cover 3. Compared with the use mode in which the flip cover 3 in other devices can only control the opening and closing of the outlet 2, and the dispensing mechanism 4 is actuated by additional parts such as a driving rod, a motor, etc., the present application links the flip cover 3 with the ratchet assembly 42 of the dispensing mechanism 4, and while simplifying the device structure, the flip cover 3 can also selectively actuate the dispensing mechanism 4, thereby improving the convenience of use.

[0074] Furthermore, the interface 311 has a guide groove 312 extending toward the edge of the rotating portion 31 to better guide the interface 311 to cooperate with the docking portion on the ratchet assembly 42 , for example, to guide the convex key 4223 on the second wheel 422 of the ratchet assembly 42 to slide toward the interface 311 .

[0075] See you next time Figure 2 and Figure 4 As shown, when the flip cover 3 is in the first position of the device, the flip cover 3 can cover the air grille 13 to prevent the receiving station 5 from being contaminated, and when the device is in the third position, the air grille 13 is completely exposed to provide sufficient auxiliary airflow inside the receiving station 5.

[0076] like Fig. 9 and Fig.10 As shown, the convex portion 14 of the dispenser housing 1 is provided with a first retaining groove 142 , the rotating portion 31 of the flip cover 3 is provided with a second retaining groove 313 , one end of the torsion piece 61 is connected to the first retaining groove 142 , and the other end is connected to the second retaining groove 313 .

[0077] Figure 5 It is shown that the convex part 14 has an assembly cavity 143 that limits the rotation angle of the rotating part 31 to 0°-110°. The preferred rotation angle is limited to 0°-108°. Within this angle range, the ratchet assembly 42 connected to the flip cover 3 can successfully complete an actuation without overtravel problems.

[0078] See also Figure 6 , Fig.11 and Fig.12 As shown, the dispensing mechanism 4 is arranged in the dispenser housing 1, and the dispensing mechanism 4 includes a mounting frame 41 and a ratchet assembly 42, a transmission assembly 43 and a stripping assembly 44 arranged on the mounting frame 41. Among them, the mounting frame 41 is fixedly arranged in the dispenser housing 1, and the ratchet assembly 42 can selectively link with the transmission assembly 43 according to the position of the flip cover 3, thereby prompting the stripping assembly 44 to perform relevant actions to open the pouch 81 on the drug carrier 8 and reel in the stripped base sheet 82 and cover sheet 83 respectively.

[0079] Fig.17 The ratchet assembly 42 includes a first wheel 421 and a second wheel 422. Figures 13 to 15 and Fig.19 As shown, the first wheel 421 is rotatably arranged on the main shaft 411 of the mounting frame 41, and the second wheel 422 is rotatably arranged on the first wheel 421. The second wheel 422 can idle from the first position of the device to the second position. During this process, the second wheel 422 idles 20°, and the first wheel 421 remains stationary. The second wheel 422 engages with the first wheel 421 at the second position of the device and then rotates to the third position. During this process, the second wheel 422 drives the first wheel 421 to rotate synchronously by 88°, and at the same time, the first wheel 421 drives the target device, that is, the sheet driver 441 of the stripping assembly 44, so as to prompt the sheet driver 441 to perform the stripping and winding functions. Compared with other devices in which the sheet driver 441 is directly actuated to perform corresponding actions, the present application links the ratchet assembly 42 with the sheet driver 441 (through the transmission assembly 43). While facilitating operation, the present application utilizes the idle rotation design of the ratchet assembly 42 to provide a safety measure for the action of the sheet driver 441 of the peeling assembly 44, thereby effectively avoiding unexpected peeling actions caused by the small-distance movement of the flip cover 3, thereby providing the device with the function of preventing misoperation and improving the reliability of use.

[0080] Specifically, at least one ratchet piece 4211 is circumferentially provided on the first wheel 421, and at least one ratchet arm 4221 is circumferentially provided on the second wheel 422. As an example, five ratchet pieces 4211 are circumferentially provided on the first wheel 421, and five ratchet arms 4221 are also circumferentially provided on the second wheel 422. The ratchet arms 4221 correspond to and cooperate with the ratchet pieces 4211 one by one, thereby ensuring stable transmission and uniform force. In addition, the ratchet arms 4221 are engaged with the ratchet pieces 4211 only during the period from the second position of the device to the third position, thereby driving the first wheel 421 to rotate unidirectionally, providing power for the stripping assembly 44.

[0081] Fig.16a The figure shows the state of the first wheel 421 / the second wheel 422 in the reference position. Under normal circumstances, as the flip cover 3 is reset, the first wheel 421 and the second wheel 422 of the ratchet assembly 42 are also limited by the retaining plate 45. That is, in the reference position, the first wheel 421 is in conflict with the elastic hook 451 on the retaining plate 45 through the outer tooth structure 42115 of the ratchet member 4211, and the second wheel 422 is engaged with the arc groove 452 on the retaining plate 45 through the positioning protrusion 4222.

[0082] In the ratchet assembly 42, the second wheel 422 can reset the first wheel 421 to the reference position by generating a static friction damping force with the first wheel 421. That is, when the second wheel 422 rotates from the third position of the device to the first position, the pawl arm 4221 can fit with the ratchet member 4211 and generate a static friction damping force to make the first wheel 421 rotate clockwise, and the outer tooth structure 42115 of the ratchet member 4211 contacts the elastic hook 451 on the retaining plate 45, thereby keeping the first wheel 421 in the reference position. However, as the number of times the device is used increases, the static friction damping force will gradually become smaller than the torque required for calibration of the first wheel 421, resulting in the first wheel 421 still deviating from the reference position after the second wheel 422 rotates to the first position, that is, Fig.16b As shown, there is a distance between the outer tooth structure 42115 of the ratchet member 4211 and the elastic hook 451 on the retaining plate, which causes an error in the position accuracy of the first wheel 421. As a result, the bag 81 of the drug carrier 8 cannot be accurately distributed to the receiving station 5 during the next actuation, affecting the user's inhalation or making it impossible to inhale the correct dose, which is not what the design intended.

[0083] For this purpose, see Figures 18 to 20 As shown, in a preferred embodiment, a sliding unit 423 is provided between the first wheel 421 and the second wheel 422, and the sliding unit 423 is configured to form a mechanical rigid connection with the first wheel 421 before the second wheel 422 rotates from the third position of the device to the first position, thereby forcing the first wheel 421 to be reset to the reference position, thereby improving the accuracy and reliability of the actuation of the ratchet assembly 42.

[0084] The sliding block unit 423 includes a sliding groove 4231 arranged on the first wheel 421 and a stopper 4232 arranged on the second wheel 422. As an example, the upper wheel surface of the first wheel 421 has five sliding grooves 4231 evenly spaced in the circumferential direction, and the lower wheel surface of the second wheel 422 has five stoppers 4232 evenly spaced in the circumferential direction, and each stopper 4232 is slidably arranged in the corresponding sliding groove 4231. Before the second wheel 422 rotates from the third position of the device to the first position, the stopper 4232 will firstly conflict with the end of the current sliding groove 4231, forming a Fig.18 It should be noted that the block 4232 and the slide 4231 in the present application are very small components, and the interference force generated by the cooperation of the two is less than the limiting force of the retaining plate 45 on the first wheel 421, but still stronger than the static friction damping force mentioned above. As the second wheel 422 continues to rotate, the first wheel 421 is pushed to reset to the reference position and is restricted by the retaining plate 45, while the block 4232 is forced to cross the current slide 4231 and enter the adjacent slide 4231, waiting for the next actuation of the ratchet assembly 42. The addition of the slide unit 423 makes the position of the first wheel 421 accurately controllable after each actuation of the ratchet assembly 42, thereby ensuring that the capsule 81 on the drug carrier 8 can be effectively in place, improving the reliability of the drug delivery of the dispensing mechanism 4. Of course, in some alternative embodiments, the positions of the slide groove 4231 and the block 4232 may also be interchanged. For example, the slide unit 423 may also include a block 4232 arranged on the first wheel 421 and a slide groove 4231 arranged on the second wheel 422, which will not be repeated here.

[0085] like Fig.19 As shown, in the ratchet assembly 42, the main shaft 411 for mounting the first wheel 421 is preferably a toothed shaft to reduce the rotational friction between the first wheel 421. Correspondingly, the first wheel 421 is provided with a mounting hole 4213 that matches the main shaft 411, and a plurality of recessed areas 4214 are arranged at intervals on the outer periphery of the mounting hole 4213, and the recessed areas 4214 are arranged close to the inner side of the slide groove 4231. In the present application, the recessed areas 4214 make the thickness of the mounting hole 4213 tend to be balanced, avoiding shrinkage deformation caused by uneven thickness of the first wheel 421 during molding, ensuring that the structural quality and precision of the mounting hole 4213 meet the requirements, and on the other hand, the recessed areas also reduce the weight and raw materials of the first wheel 421, thereby reducing its molding cost.

[0086] exist Figures 13 to 17In the ratchet assembly 42 shown, the ratchet member 4211 of the first wheel 421 has an inner surface with a stepped profile, and the inner surface includes a first guide segment 42111 and a friction-fitting segment 42112. The first guide segment 42111 is used to guide the pawl arm 4221 to enter the engaged position during the idle rotation of the second wheel 422 from the first position to the second position, and an inner tooth structure 42113 is formed at the connection between the first guide segment 42111 and the friction-fitting segment 42112, and the inner tooth structure 42113 can be engaged with the pawl arm 4221 when the second wheel 422 rotates to the second position, thereby forcing the first wheel 421 to rotate unidirectionally by a certain angle, for example, the first wheel 421 rotates 88° counterclockwise.

[0087] The friction fitting section 42112 is closer to the pawl arm 4221 than the first guiding section 42111, so that during the period when the second wheel 422 moves from the third position to the first position, the pawl arm 4221 can fit with the friction fitting section 42112 to generate static friction damping force, thereby causing the first wheel 421 to be reset to the reference position and remain restricted. As the second wheel 422 continues to rotate relative to the first position, the torque applied to the second wheel 422 when the flip cover 3 is reset and closed is greater than the static friction damping force, and the pawl arm 4221 separates from the friction fitting section 42112, thereby finally causing the first wheel to rotate to the first position of the device.

[0088] In addition, the ratchet member 4211 also has an outer surface extending toward the outer circumference, and the outer surface includes a second guide segment 42114. The second guide segment 42114 is used to guide the outer surface of the ratchet member 4211 to move and force the elastic hook 451 on the retaining plate 45 to expand and deform outward when the second wheel 422 rotates from the second position of the device to the third position. In addition, an outer tooth structure 42115 is formed at the connection between the outermost end of the second guide segment 42114 and the edge of the first wheel 421. When the second wheel 422 rotates to the third position of the device, the outer tooth structure 42115 can pass over the elastic hook 451 and, under the action of the rigid connection of the sliding unit 423 and / or the action of the static friction damping force generated by the fit between the pawl arm 4221 and the ratchet member 4211, it will conflict with the elastic hook 451, thereby keeping the first wheel 421 in the reference position. Fig.16a .

[0089] Correspondingly, the outer periphery of the second wheel 422 is also provided with a positioning protrusion 4222. When the second wheel 422 returns to the first position of the device, the positioning protrusion 4222 can be engaged with the arc groove 452 on the retaining plate 45, so that the second wheel 422 is maintained at the reference position. Fig.16a .

[0090] See also Fig.12 and Fig.18As shown, in the ratchet assembly 42, the first wheel 421 is used as a power output part, and a main gear 4212 is provided on a side away from the second wheel 422. Preferably, the main gear 4212 is coaxial with the first wheel 421 and is integrally formed, so that the concentricity and bonding strength of the main gear 4212 and the first wheel 421 are effectively guaranteed, and the lateral arrangement of the main gear 4212 is more convenient for meshing and mounting with the transmission assembly 43.

[0091] A convex key 4223 is provided on a side of the second wheel 422 away from the first wheel 421. Figure 6 and Fig.17 As shown, the convex key 4223 matches the interface 311 at the rotating part 31 of the flip cover 3, and can slide quickly and embed into the interface 311 under the guidance of the guide groove 312, so that the flip cover 3 and the second wheel 422 are mechanically connected together.

[0092] See also Figures 12 to 15 As shown, the transmission assembly 43 is disposed between the ratchet assembly 42 and the stripping assembly 44, and plays the role of transmitting power and delivering the drug carrier 8. In some embodiments, the transmission assembly 43 is a gear assembly composed of a plurality of gear components, and is respectively connected to the ratchet assembly 42 and the stripping assembly 44 in the form of tooth meshing.

[0093] Figure 7 , Fig.11 and 12 The figure shows a partial structure of the transmission assembly 43, which is the indexing wheel 431 in the transmission assembly 43. The indexing wheel 431 is provided with grooves 4311 for receiving the pouches 81 in the circumferential direction. For example, the number of the grooves 4311 can be 2-6. As the ratchet assembly 42 is actuated, the second wheel 422 moves from the second position to the third position of the device, and the previous groove 4311 on the indexing wheel 431 delivers the previous pouch 81 on the drug carrier 8 to the receiving station 5, and the next groove 4311 on the indexing wheel 431 docks with the next pouch 81 on the drug carrier 8, so that the drugs are delivered one by one in an orderly manner, and the pouches 81 are opened in cooperation with the stripping assembly 44, so that the drug powder enters the receiving station 5.

[0094] Figure 11 to Figure 12 The stripping assembly 44 is shown to include a sheet driver 441. The sheet driver 441 is located at the top of the dispenser body and is arranged close to the receiving station 5. The sheet driver 441 is used to connect the front end of the cover sheet 83, provide the main power for stripping the drug carrier 8 and opening the pouch 81, and reel in the discarded cover sheet 83 that has been stripped.

[0095] See also Figure 21 to Figure 24As shown, in a preferred embodiment, the sheet driver 441 includes a driving portion 4411, a shaft portion 4412, a hub 4413 and an elastic arm 4414. The shaft portion 4412 extends perpendicularly to the driving portion 4411; the hub 4413 is arranged on one side of the driving portion 4411 and can rotate around the shaft portion 4412; the elastic arm 4414 extends from the outer periphery of the shaft portion 4412 toward the inner wall of the hub 4413, and the elastic arm 4414 is connected to the hub 4413 through a quick-connect structure. When the hub 4413 rotates relative to the shaft portion 4412, the corresponding flip cover 3 / second wheel 422 moves from the second position of the device to the third position. During this period, the elastic arm 4414 can deflect clockwise / counterclockwise to provide tension compensation, and even if the effective winding surface diameter of the hub 4413 is arbitrarily increased, it will not affect the uniform division of the drug carrier 8.

[0096] It should be noted that the existing sheet drive (distinguishing between left and right) usually realizes tension compensation with a built-in torsion spring, and each sheet drive can only rotate in a single direction to provide tension compensation. However, the sheet drive 441 of the present application realizes tension compensation by using an elastic arm 4414 to deflect clockwise / counterclockwise, and only one elastic arm 4414 is needed to simultaneously meet the left and right (i.e. clockwise / counterclockwise) deflection requirements. It integrates the left and right sheet drive components into one device, which has better versatility. In particular, during the installation process, the sheet drive 441 no longer needs to distinguish between left and right, which effectively improves production efficiency and assembly convenience.

[0097] In addition, if Fig.23 As shown, in the above-mentioned sheet driver 441, the shaft 4412 extends perpendicularly to the driving part 4411, the shaft 4412 and the driving part 4411 can be integrally formed, and the elastic arm 4414 extends from the outer periphery of the shaft 4412 toward the inner wall of the hub 4413, and the shaft 4412 and the elastic arm 4414 can also be integrally formed, which makes the driving part 4411, the shaft 4412 and the elastic arm 4414 become one part, and the hub 4413 is another part. During assembly, the hub 4413 is directly sleeved on the shaft 4412, and the elastic arm 4414 is connected to the hub 4413 through a quick-connect structure. Compared with the existing sheet driver, the sheet driver 441 of the present application has fewer parts and is quick to assemble. Especially in mass production, the sheet driver 441 can effectively reduce production costs and improve assembly efficiency.

[0098] See also Fig.23 and Fig.24As shown, the quick-connect structure includes a fixing member 44135 disposed in the shaft hub 4413 and a counter member 44141 disposed on the elastic arm 44144114. By matching the counter member 44141 with the fixing member 44135, the assembly of the sheet driver 441 can be completed quickly. The shape and structure of the fixing member 44135 and the counter member 44141 are not limited. For example, it can be Fig.24 As shown, the fixing member 44135 is a cross rib integrally formed at the inner top of the shaft hub 4413, and the hand member 44141 is a jacket formed by extending and bending the elastic arm 4414, wherein the jacket can be detachably mounted on the cross rib, thereby realizing a quick connection between the shaft hub 4413 and the elastic arm 4414, and facilitating the replacement of faulty parts. For another example, the fixing member 44135 can also be a slot integrally formed at the inner top of the shaft hub 4413, and the hand member 44141 is a buckle formed by extending from the elastic arm 4414, wherein the buckle can be detachably inserted in the slot (not shown).

[0099] Further, Fig. 22 The driving part 4411 is provided with an observation port 44111, and the position of the observation port 44111 is opposite to the position of the quick-connect structure. During assembly, the positions of the fixing member 44135 and the pair member 44141 can be determined through the observation port 44111, and the alignment can be completed by adjusting the angle appropriately, so as to facilitate the assembly of the film driver 441.

[0100] In the above-mentioned sheet driver 441, the driving part 4411 is preferably a driving gear, and the first wheel 421 of the ratchet assembly 42 can be linked with the driving part 4411 through the indexing wheel 431 of the transmission assembly 43, and the sheet driver 441 is controlled by the flip cover 3. Compared with the use mode in which the sheet driver 441 is actuated by additional parts in other devices, the present application links the sheet driver 441 with the flip cover 3, which simplifies the operation and facilitates the user to control the moving sheet driver 441 to perform related actions through the flip cover 3. Of course, in some alternative modes, the driving part 4411 can also be a driving wheel, and the first wheel 421 of the ratchet assembly 42 can be linked with the indexing wheel 431 of the transmission assembly 43 and / or the driving part 4411 of the sheet driver 441 through belt drive, friction drive, etc. (not shown).

[0101] Or Fig. 22 As shown, a center hole 44121 extending to the driving part 4411 is provided in the shaft part 4412. On one hand, the center hole 44121 can reduce the overall weight of the sheet driver 441, so that the power transmitted to the driving part 4411 can drive the shaft hub 4413 to peel off and wind the cover sheet 83 more smoothly; on the other hand, the center hole 44121 can play a positioning role during molding, which is conducive to the integral molding of the shaft part 4412 and the driving part 4411.

[0102] See also Fig.21 As shown, the end of the hub 4413 away from the driving portion 4411 is provided with an assembly hole 44131, and the hub 4413 is sleeved on the shaft portion 4412 through the assembly hole 44131. Fig.23 As shown, an annular flange 44122 is provided on the outer periphery of the shaft portion 4412, the outer diameter of the flange 44122 is larger than the aperture of the assembly hole 44131, and the distance from the flange 44122 to the driving portion 4411 is greater than or equal to the distance from the assembly hole 44131 to the driving portion 4411, thereby stably restricting the hub 4413 on the shaft portion 4412 to prevent it from falling off, thereby ensuring the stability of the rotation of the hub 4413.

[0103] The surface of the hub 4413 is configured to receive the target piece, for example, in the present application, the surface of the hub 4413 is used to receive the front end portion of the cover piece 83. Further, Fig.21 The hub 4413 shown is provided with a groove 44132 at the automatic edge and a hook 44133 is formed thereon, so as to better receive the front end portion of the cover sheet 83. Preferably, the front end portion of the cover sheet 83 is a block structure or an annular structure, so as to better connect and cooperate with the groove 44132 or the hook 44133.

[0104] Furthermore, at least one cut surface is provided on the outer periphery of the shaft hub 4413; and / or, the surface of the shaft hub 4413 is provided with a texture or coating (to increase the surface roughness). The cut surface and / or the texture or coating can enhance the connection between the surface of the shaft hub 4413 and the cover sheet 83 during winding, thereby ensuring that the cover sheet 83 can be tightly wound on the shaft hub 4413, avoiding the effect on the peeling of the drug carrier 8.

[0105] See also Fig.23 and Fig.24 As shown, a plurality of vertical ribs 44134 are arranged at intervals on the inner wall of the shaft hub 4413, a boss 44112 is arranged on the side of the driving portion 4411 close to the shaft hub 4413, and the vertical ribs 44134 are provided with corners riding on the boss 44112. On one hand, the vertical ribs 44134 can enhance the structural strength of the shaft hub 4413, and on the other hand, after the corners of the vertical ribs 44134 cooperate with the boss 44112, the shaft hub 4413 can be rotationally limited to ensure that the shaft hub 4413 does not deflect when rotating around the shaft portion 4412, thereby improving the stability of the operation of the sheet driver 441.

[0106] See also Fig.11 , Fig.12It is shown that the stripping assembly 44 also includes a substrate winding reel 442. The substrate winding reel 442 is located at the bottom position in the dispenser housing 1 and is arranged away from the receiving station 5. The substrate winding reel 442 is used to connect the front end of the substrate 82 and reel in the stripped waste substrate 82. The substrate winding reel 442 is also driven and controlled by the first wheel 421 of the ratchet assembly 42 through the transmission assembly 43, and its action of winding the substrate 82 is always synchronized with the action of the sheet driver 441 winding the cover sheet 83. In some other embodiments, the sheet driver 441 can also be used to replace the substrate winding reel 442 to wind the substrate 82 (not shown).

[0107] Furthermore, the substrate winding reel 442 is also connected to a counter 7, such as Fig.25 As shown, the counter 7 is preferably a mechanical counter, which is installed in the dispenser housing 1 and can expose the counting part. When the flip cover 3 moves from the second position of the device to the third position, the ratchet assembly 42 generates an actuation, thereby driving the substrate to rotate around the reel 442 and the counter 7 performs a counting action to display the remaining number of times the device can be used, which is convenient for users.

[0108] The above-mentioned drug dispensing device can be designed to receive a single drug carrier 8 to form a "single-active" drug therapy, or it can be designed to receive multiple drug carriers 8, different drug carriers 8 can provide different drug powders, which when mixed together form a "multi-active" drug therapy.

[0109] by Figure 7For example, in the present application, the drug dispensing device is preferably equipped with two drug carriers 8, which are symmetrically arranged about the central axis of the device, and the distribution mechanism 4 has two indexing wheels 431 and stripping components 44, which are also symmetrically arranged about the central axis of the device. When in use, the flip cover 3 is first moved from the first position of the device to the second position, and correspondingly, the second wheel 422 of the ratchet assembly 42 rotates counterclockwise for 20 degrees and then just engages with the first wheel 421, but this process does not actuate the stripping component 44. As the flip cover 3 moves from the second position of the device to the third position and is limited there, the second wheel 422 of the ratchet assembly 42 drives the first wheel 421 to rotate 88° counterclockwise, and the first wheel 421 delivers the pouch 81 on the drug carrier 8 to the receiving station 5 through the indexing wheel 431 of the transmission assembly 43, and during this period, the transmission assembly 43 actuates the sheet driver 441 and the substrate to rotate synchronously around the reel 442 to respectively wind the cover sheet 83 and the substrate 82, thereby opening the pouch 81 to expose the two drug powders to the receiving hole 51 of the receiving station 5, which means that the device is ready for use. The user can place the outlet 2 at the mouth and absorb the mixed drug powder for treatment. After use, the user can press the button 63 to automatically reset the flip cover 3 from the third position of the device to the first position, and the corresponding second wheel 422 of the ratchet assembly 42 rotates 108° clockwise to reset, while keeping the first wheel 421 at the reference position. This process does not actuate the stripping assembly 44 until the flip cover 3 covers the outlet 2 and waits for the next use of the device.

[0110] The drug dispensing device is suitable for dispensing pharmaceutical products, especially for treating respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD), bronchitis and chest infections. In addition, it can also be used to treat diseases that require systemic circulation of drugs, such as migraine, diabetes, etc.

[0111] Suitable drugs may thus be selected from, for example, analgesics such as codeine, dihydromorphine, ergotamine, fentanyl or morphine; angina preparations such as diltiazem; antiallergics such as cromoglycate (e.g. as sodium salt), metioxetine or nedocromil (e.g. as sodium salt); anti-infectives such as cephalosporins, penicillins, streptomycin, sulfonamides, tetracyclines and pentamidine; antihistamines such as methamphetamine; anti-inflammatory drugs such as beclomethasone (e.g. as dipropionate), fluticasone (e.g. as propionate), fluticasone acetonide, budesonide, lobonide, mometasone (e.g. as furoate), ciclesonide, triamcinolone acetate (e.g. as propionate), and phenoxyethanol. ketone compounds) or 6α, 9α-difluoro-11β-hydroxy-16α-methyl-3-oxo-17α-propionyl-androsta-1,4-diene-17β-thiocarboxylic acid S-(2-oxo-tetrahydro-furan-3-yl) ester; cough suppressants, such as narcotine; bronchodilators, such as albuterol (e.g. as free base or sulfate), salmeterol (e.g. as sinafide), ephedrine, adrenaline, phenterol (e.g. as hydrobromide), formoterol (e.g. as fumarate), phentermine, dihydroxyphenylisopropylaminoethanol, phenylephrine, phenylpropanolamine, pirbuterol (e.g. as acetate), theaproterenol (e.g. as hydrochloride), hydroxypiperidinol, terbutaline (e.g. as sulfate), isoprenaline, tolbuterol or 4-hydroxy-7-[[2-[[3-(2-phenylethoxy)propyl]sulfonyl]ethyl]amino]ethyl-2(3H)-benzothiazolone; adenosine 2a agonists, such as (2R,3R,4S,5R)-2-[6-amino-2-(1S-hydroxymethyl-2-phenyl-ethylamino)-caffein-9-yl]-5-(2-ethyl-2H-tetrazol-5-yl)-tetrahydro-furan-3,4-diol (e.g. as maleate); alpha 4 integrin inhibitors, such as (2S)-3-[4-({[4-(aminocarbonyl)-1-linear urea]carbonyl}oxy)phenyl]-2-[((2S)-4-methyl-2-{[2-(2

[0013] In some embodiments, the present invention relates to a pharmaceutical composition comprising: a) 1,2-dimethoxy- ...

[0112] Although the embodiments of the present invention have been shown and described above, it is to be understood that the above embodiments are exemplary and are not to be construed as limitations on the present invention. A person skilled in the art may change, modify, substitute and modify the above embodiments within the scope of the invention without departing from the principles and purpose of the present invention. All such changes should fall within the scope of protection of the claims of the present invention.

Claims

1. A drug dispensing device, characterized in that: include: The sheet driver (441) comprises a shaft portion (4412), a shaft hub (4413) rotatably disposed on the shaft portion (4412), and an elastic arm (4414) extending from the shaft portion (4412) toward the shaft hub (4413) and connected to the shaft hub (4413); A ratchet assembly (42) comprising a first wheel (421) drivingly connected to the shaft portion (4412), and a second wheel (422) rotatably disposed on the first wheel (421); The drug dispensing device is configured to control the sheet driver (441) to perform a winding action by a ratchet assembly (42), wherein the second wheel (422) can idle from a first position to a second position, and after engaging the first wheel (421) at the second position, they can rotate together to a third position, thereby driving the hub (4413) to wind up the target sheet, and the elastic arm (4414) can swing clockwise / counterclockwise to provide tension compensation for its winding.

2. The drug dispensing device according to claim 1, characterized in that The sheet driver (441) further comprises a driving portion (4411), wherein the driving portion (4411) is vertically connected to the shaft portion (4412).

3. The drug dispensing device according to claim 2, characterized in that The outer periphery of the shaft portion (4412) is provided with a flange (44122), and the center of the shaft hub (4413) is provided with an assembly hole (44131); The outer diameter of the flange (44122) is greater than the diameter of the assembly hole (44131), and the distance from the flange (44122) to the driving part (4411) is greater than or equal to the distance from the assembly hole (44131) to the driving part (4411).

4. The drug dispensing device according to claim 2, characterized in that The elastic arm (4414) is connected to the shaft hub (4413) via a quick-connect structure, and the quick-connect structure comprises: A fixing member (44135) is arranged on the inner top of the shaft hub (4413), and the fixing member (44135) is a cross rib; The pair of hand pieces (44141) are arranged on the elastic arm (4414); the pair of hand pieces (44141) are jackets that are detachably mounted on the cross ribs.

5. The drug dispensing device according to claim 1, characterized in that There are two sheet drivers (411) symmetrically distributed on the left and right sides of the central axis of the device, and the reeling directions of the respective hubs (4413) of the two sheet drivers (411) are opposite.

6. The drug dispensing device according to claim 4, characterized in that The shaft portion (4412), the elastic arm (4414) and the pair of opposite parts (44141) are integrally formed, and the shaft hub (4413) and the fixing part (44135) are integrally formed.

7. The drug dispensing device according to claim 2, characterized in that A main gear (4212) is provided on a side of the first wheel (421) away from the second wheel (422), and the main gear (4212) is transmission-connected to the driving part (4411) via a dividing wheel (431).

8. The drug dispensing device according to claim 1, characterized in that A ratchet piece (4211) is provided on the outer periphery of the first wheel (421), and a ratchet arm (4221) is provided on the outer periphery of the second wheel (422); When the second wheel (422) rotates from the second position to the third position, the ratchet arm (4221) engages with the ratchet member (4211), and the shaft portion (4412) is driven to rotate by the first wheel (421).

9. The drug dispensing device according to claim 1, characterized in that During the period when the second wheel (422) rotates from the third position to the first position, the inner side surface of the ratchet member (4211) can be in contact with the outer side surface of the ratchet arm (4221), thereby generating a static friction damping force.

10. The drug dispensing device according to claim 1, characterized in that A sliding block (423) is provided between the first and second wheels (421, 422), and the sliding block (423) comprises a sliding groove (4231) provided on the first wheel (421) and a stopper (4232) provided on the second wheel (422); Before the second wheel (422) rotates from the third position to the first position, the stopper (4232) can abut against the end of the slide groove (4231), so that the first and second wheels (421, 422) form a mechanical rigid connection, thereby forcing the first wheel (421) to reset to the reference position.

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