Composition for treating constipation as well as preparation method and application thereof

Abstract

The invention provides a composition for constipation and a preparation method and application thereof.The composition is prepared from 130-140 parts of pumpkin powder, 30-35 parts of poria cocos powder, 40-50 parts of tremella powder, 80-90 parts of aloe powder and 80-90 parts of prebiotics. The preparation method of the composition for constipation comprises the following steps that 1, the pumpkin powder is prepared; step 2, preparing poria cocos powder; step 3, preparing tremella powder; step 4, preparing aloe powder; step 5, preparing the composition for treating constipation; uniformly mixing the pumpkin powder, the poria cocos powder, the tremella powder, the aloe powder and the prebiotics prepared in the steps 1-5 to prepare capsules, so as to obtain the composition for treating constipation. Through advanced processes of supercritical extraction, vacuum freeze drying, superfine grinding and the like, effective components in raw materials such as pumpkins, poria cocos, tremella fuciformis and aloe can be extracted and reserved to the maximum extent, and the pumpkin-poria cocos-aloe powder is suitable for being eaten for a long time.

Description

Technical Field

[0001] The invention relates to the technical field of health food, in particular to a composition for constipation and a preparation method and application thereof. Background Art

[0002] Constipation is a common digestive system problem, usually manifested as difficulty in defecation, less frequent bowel movements, or hard stools. Its causes are complex, including dietary habits, lifestyle, drug side effects, intestinal diseases, etc. Traditionally, methods for treating constipation include changing dietary habits, increasing dietary fiber intake, using laxatives, etc. However, these methods often have side effects or poor long-term effects.

[0003] A Chinese patent document with application publication number "CN 115316623 A" discloses a composition for constipation and a raw material powder-forming device thereof, wherein the weight composition of the composition is 120 parts of pumpkin powder, 40 parts of Poria cocos, 100 parts of aloe vera, 40 parts of Tremella fuciformis, and 100 parts of prebiotics, and the preparation method comprises the following steps: S1: Poria cocos, aloe vera, and Tremella fuciformis are dried to a moisture content of 4.0% respectively, and are crushed by a powder-forming device respectively, and the particle sizes are all above 300 meshes to obtain Poria cocos powder, aloe vera powder, and Tremella fuciformis powder; S2: Pumpkin powder, aloe vera powder, Poria cocos powder, Tremella fuciformis powder, and prebiotics according to the weight of each component of the composition are sucked into a mixer in turn for total mixing to obtain a mixed powder; S3: The mixed powder is added to a capsule filling machine for filling to obtain capsule particles containing medicinal powder, and the mixture is polished and inspected to obtain qualified capsule particles; S4: The qualified capsule particles are packaged in an aluminum-plastic package or bottled.

[0004] However, this method adopts a simple powder mixing process, which fails to fully activate the beneficial ingredients of each component, resulting in poor application effect. It also fails to remove useless ingredients in each formula, contains more impurities, and has a poor taste. Based on this, there is an urgent need for another composition for constipation and its preparation method and application to solve the above technical problems. Summary of the invention

[0005] In order to solve the above technical problems, the present invention provides a composition for constipation, comprising 130-140 parts of pumpkin powder, 30-35 parts of Poria powder, 40-50 parts of Tremella powder, 80-90 parts of aloe powder, and 80-90 parts of prebiotics. The preparation method of the composition for constipation is as follows: Fig.18 As shown, the details are as follows:

[0006] Step 1: Prepare pumpkin powder

[0007] S11. Material selection and cleaning: select old pumpkins that are highly mature and not rotten or deteriorated, remove the pedicel and stem, clean and remove the sand and impurities on the surface, then drain, soak the pumpkin in disinfectant to kill the mold on the surface, and then wash it with drinking water 3-4 times to remove the residual solvent;

[0008] S12, slicing and blanching: cutting the washed pumpkin into slices, and then blanching;

[0009] S13, vacuum freeze drying: vacuum freeze drying the blanched pumpkin slices;

[0010] S14, ultrafine grinding: ultrafine grinding the vacuum freeze-dried pumpkin slices to more than 200 meshes using an ultrafine grinder in a closed environment;

[0011] S15, fermentation: inoculate the ultrafinely crushed pumpkin powder with a compound lactic acid bacteria starter, and ferment at 18-25° C. for 7-15 days until the pH value at the end of the fermentation is 3.0-3.5;

[0012] S16, drying: drying at 40° C. to 60° C. to make the water content less than or equal to 5% to obtain pumpkin powder, and storing it in a dark place at a humidity less than 50% and a temperature below 25° C. for standby use;

[0013] Step 2: Prepare Poria powder

[0014] S21, raw material preparation: select dry, mildew-free Poria cocos and crush it into 20-60 mesh;

[0015] S22, supercritical extraction: subjecting the crushed Poria cocos powder to supercritical extraction;

[0016] S23, separation and concentration: after the supercritical extraction is completed, an extract containing the effective ingredients of Poria cocos is separated and concentrated to remove excess solvent and impurities to obtain a concentrated Poria cocos extract;

[0017] S24, vacuum freeze drying: vacuum freeze drying the concentrated Poria cocos extract until the water content is less than or equal to 5%;

[0018] S25, ultrafine grinding: ultrafine grinding the vacuum dried Poria cocos to more than 200 meshes with an ultrafine grinder in a closed environment to obtain Poria cocos powder, which is stored in a dark place at a humidity of less than 50% and a temperature below 25° C. for later use;

[0019] Step 3: Prepare Tremella Powder

[0020] S31, raw material preparation: select dry, mildew-free Tremella fuciformis and crush it to more than 100 mesh;

[0021] S32, suspension preparation: mixing the crushed Tremella fuciformis with water to form a suspension;

[0022] S33, pH adjustment: add citric acid to the suspension to adjust the pH value to within the range of 4-5;

[0023] S34, enzymatic hydrolysis: at a temperature of 50-60° C., pectinase, acid cellulase, and neutral protease are sequentially added to the suspension for enzymatic hydrolysis;

[0024] S35, filtering and drying: After the enzymatic hydrolysis is completed, the suspension is centrifuged, the liquid component is taken, concentrated, dried, and ultrafinely crushed to more than 200 meshes to obtain Tremella powder, which is stored in a dark place at a humidity of less than 50% and a temperature below 25° C. for standby use;

[0025] Step 4: Prepare aloe vera powder

[0026] S41. Raw material preparation: select fresh aloe leaves free of pests and diseases, wash and remove impurities;

[0027] S42, cutting and crushing: cutting the cleaned aloe leaves into blocks of appropriate size using an aloe crusher, and then crushing and beating them using an aloe crusher until fine aloe pulp is formed; this step is intended to destroy the aloe cell wall and provide favorable conditions for subsequent enzymatic hydrolysis;

[0028] S43, enzymatic hydrolysis: adding pectinase, acid cellulase and neutral protease to the aloe pulp in sequence at a temperature of 40-50° C. for enzymatic hydrolysis;

[0029] S44, centrifugation and filtration: After the enzymatic hydrolysis is completed, the aloe slurry is centrifuged to obtain a liquid component, which is filtered again to further remove tiny particles and impurities, and then concentrated and dried;

[0030] S45. Grinding: ultrafinely grind to more than 200 meshes to obtain aloe vera powder, and store it in a dark place at a humidity of less than 50% and a temperature below 25° C. for later use.

[0031] Step 5: Prepare a composition for constipation

[0032] 130-140 parts of pumpkin powder, 30-35 parts of Poria powder, 40-50 parts of Tremella powder, 80-90 parts of aloe powder and 80-90 parts of prebiotics are uniformly mixed to prepare capsules to obtain a composition for constipation.

[0033] Furthermore, in the step 1, when preparing pumpkin powder:

[0034] In step S12, the washed pumpkin is cut into slices of 5-8 cm x 5-8 cm x 2 cm; the blanching treatment is to blanch the pumpkin slices in 90° C. boiling water for 2-3 minutes to protect the color and partially soften the tissue;

[0035] Step S13, the vacuum freeze drying process is as follows:

[0036] Pre-freezing stage: Freeze at -20 to -30°C for 10-15 hours;

[0037] Drying stage 1: Drying at a vacuum degree of 0.1-0.5mbar and a temperature of 40-50℃ for 8-10 hours;

[0038] Drying stage 2: Drying for 5-8 hours at a vacuum degree of 0.1-0.5 mbar and a temperature of 20-30°C.

[0039] In step S15, the inoculation amount of the composite lactic acid bacteria fermentation agent is 1-3% of the weight of the pumpkin powder, and the composite lactic acid bacteria fermentation agent is obtained by compounding Lactobacillus plantarum, Lactobacillus restiger and Lactobacillus brevis in a mass ratio of 2:1:1.

[0040] Furthermore, in the step 2, when preparing the Poria powder:

[0041] In step S22, the specific method of supercritical extraction is: placing the crushed Poria cocos powder in a supercritical extraction device, setting the extraction conditions to a temperature of 35-40° C., a pressure of 20-40 MPa, an extraction time of 2-4 h, and introducing carbon dioxide as an extractant for supercritical extraction;

[0042] In step S24, the specific method of vacuum freeze drying is: after pre-freezing the concentrated Poria cocos extract at -40 to -60°C for 8-10 hours, sublimation drying is performed under the conditions of vacuum degree of 10-20Pa and temperature of 30-50°C to make the water content less than or equal to 5%.

[0043] Furthermore, in the step 3, when preparing Tremella powder:

[0044] In step S32, the crushed Tremella fuciformis is mixed with water in a mass ratio of 1:5-10 to form a suspension;

[0045] In step S34, during the enzymatic hydrolysis, pectinase is first added, and the amount of pectinase added is 0.08-0.12% of the mass of the Tremella fuciformis treated in step S31, and the reaction is performed for 80-90 minutes;

[0046] Then add acid cellulase, the amount of acid cellulase added is 0.08-0.12% of the mass of Tremella fuciformis after treatment in step S31, and react for 60-80 minutes;

[0047] Finally, neutral protease is added, and the amount of the neutral protease added is also 0.08-0.12% of the mass of the Tremella after treatment in step S31, and the reaction is carried out for 40-60 minutes.

[0048] Furthermore, in the step 4, when preparing the aloe powder:

[0049] In step S42, 5. The composition for constipation according to claim 1, wherein in step 4, when preparing aloe powder:

[0050] In step S42, the aloe vera crushing mixer includes a protective frame and a crushing structure installed inside the protective frame, one side of the protective frame is connected to a feed barrel, one side of the feed barrel is provided with a cutting structure, the cutting structure is used to cut the aloe vera into segments, the crushing structure includes a crushing protective shell, a first conveying screw rod and two crushing rollers, the interior of the feed barrel is connected to the interior of the crushing protective shell, the first conveying screw rod and the two crushing rollers are both located inside the crushing protective shell and both ends are rotatably connected to the side wall of the crushing protective shell, a plurality of meshing teeth are provided on the roller bodies of the two crushing rollers, the first conveying screw rod is located below the two crushing rollers, and the first conveying screw rod is fixedly connected to the first spiral conveying blade;

[0051] The crushing structure is provided with a guide structure for guiding the movement of the aloe vera, and the bottom of the crushing structure is provided with a separation structure for separating the crushed aloe vera into dry and wet parts. One side of the separation structure is connected to an aloe vera stirring tank, and the separation structure is connected to the aloe vera stirring tank through a liquid outlet pipe;

[0052] The meshing teeth on the two grinding rollers are staggered, the first conveying screw rod is located at the center below the two grinding rollers, the outer side wall of the first spiral conveying blade is slidably connected to the bottom of the inner cavity of the grinding protection shell, and the bottom of the grinding protection shell is provided with a first discharge port, which is located at the bottom of one side of the first conveying screw rod;

[0053] The same end of the first conveying screw rod and the two crushing rollers passes through the crushing protection shell and extends outside, the roller bodies of the two crushing rollers are respectively fixedly connected with a first driving gear and a first driven gear, a first driving motor is arranged on the side of the protection frame close to the first driving gear, and the output shaft of the first driving motor passes through the protection frame and is fixedly connected to the crushing roller connected with the first driving gear;

[0054] The first conveying screw rod is connected to one of the crushing rollers through a third transmission belt.

[0055] Furthermore, the cutting structure includes a cutting disc and a lifting plate, a slide groove and a tool installation groove are opened on the same side of the inside of the feed barrel, the lifting plate is slidably connected in the slide groove and the bottom is in contact with the upper surface of the crushing protection shell, the tool installation groove is located above the slide groove, and the cutting disc is rotatably connected in the tool installation groove;

[0056] A first through hole is provided at the bottom of the lifting plate, and transfer rods are fixedly connected to both sides of the first through hole, and the two transfer rods are rotatably connected to the same support plate, and a fixed shaft sleeve is symmetrically fixedly connected to the upper surface of the crushing protection shell on the side close to the feed barrel, and the opposite sides of the two fixed shaft sleeves are fixedly connected to pins, and the free end of the support plate is rotatably connected to the two pins;

[0057] A second drive motor is disposed at the bottom of one side of the crushing protection housing close to the feed barrel, and an output shaft of the second drive motor is fixedly connected to the bottom of the cutting disc;

[0058] One side of the lifting plate is fixedly connected to a top seat, the bottom of the top seat is rotatably connected to a roller, one end of one of the crushing rollers close to the feed barrel is fixedly connected to a main rotating rod, one side of the crushing protection shell is fixedly connected to a secondary rotating rod, the top seat, the main rotating rod and the secondary rotating rod are located on the same side, and the main rotating rod and the secondary rotating rod are connected by a fourth transmission belt transmission;

[0059] The auxiliary rotating rod is fixedly connected with a convex top wheel, and the roller is in rolling contact with the outer side surface of the convex top wheel;

[0060] Baffles are symmetrically arranged on the upper surface of one side of the crushing protection shell close to the feed barrel, and the baffles are located on both sides of the support plate.

[0061] Further, the guide structure includes a dustproof protection shell, the dustproof protection shell is symmetrically installed on both sides of the top of the crushing protection shell, and the two dustproof protection shells are provided with a second through-hole on opposite sides, the first rotating shaft is rotatably connected to the two sides of the crushing protection shell, the two first rotating shaft sleeves are provided with the same first transmission belt, a plurality of belt sleeves are fixedly connected to the outer side wall of the first transmission belt, and the upper surfaces of the plurality of belt sleeves are fixedly connected to an insertion disk, and the outer side surface of the insertion disk is rotatably connected to a pusher claw, and the pusher claw is located in the second through-hole;

[0062] A sliding groove is circumferentially provided on the upper surface of the insert plate, a sliding sleeve adapted to the sliding groove is embedded in the sliding groove, the interior of the sliding sleeve is hollow and the top is open, an ejector rod and a first pressure spring are arranged inside the sliding sleeve, the first pressure spring is sleeved on the rod body of the ejector rod and the two ends of the first pressure spring are respectively fixedly connected to the ejector rod and one side of the interior of the sliding sleeve, one end of the ejector rod passes through the sliding sleeve and extends outside;

[0063] The upper surface of the pusher claw is fixedly connected with a docking piece, and the other end of the docking piece is fixedly connected to the upper surface of one side of the ejection rod.

[0064] Furthermore, an extension plate is provided on one side of the pulverizing protection housing, and a steering gear is rotatably connected to the upper surface of the extension plate, wherein the bottom of one of the first rotating shafts penetrates the dustproof protection housing and extends outside, and a second driving gear is fixedly connected to the shaft body of the extended first rotating shaft, and the steering gear is meshed with the second driving gear;

[0065] A rotating rod is fixedly connected to the upper surface of the steering gear, a second transmission belt is sleeved on the rod of the rotating rod, and the rotating rod is transmission-connected to a first rotating shaft in a dustproof protective housing far away from the second driving gear through the second transmission belt;

[0066] The outer side walls of the two dust-proof protective shells close to the feeding barrel are both provided with avoidance grooves;

[0067] The separation structure comprises a separation protection shell and a second conveying screw rod, the separation protection shell is located below the crushing protection shell and a discharge port is arranged on one side of the top of the separation protection shell, the discharge port is communicated with the first discharge port, the second conveying screw rod is rotatably connected to the interior of the separation protection shell, a second spiral conveying blade is fixedly connected to the second conveying screw rod, a filtering part is arranged at the bottom of the separation protection shell, and an outer side wall of the second spiral conveying blade is slidably connected to an inner wall of the filtering part;

[0068] A discharge housing is fixedly sleeved on one side of the separation protection housing, the bottom of the discharge housing is open, and the bottom of the protection frame is provided with an opening connected to the discharge housing;

[0069] A limiting rod is fixedly connected to one side of the inner wall of the discharge housing, a sliding plate is slidably connected to the limiting rod, a second pressure spring is sleeved on the limiting rod, the second pressure spring is located between the sliding plate and the discharge housing, and two ends of the second pressure spring are respectively fixedly connected to the sliding plate and the discharge housing;

[0070] One end of the second conveying screw rod away from the feeding barrel passes through the separation protection shell and extends outside, and the second conveying screw rod is connected to the first conveying screw rod through a fifth transmission belt.

[0071] The bottom of the separation protection shell is fixedly connected to a collection frame, the bottom of the inner cavity of the collection frame is provided with an inclined surface, one side of the collection frame is connected to a liquid outlet pipe, the collection frame is connected to the aloe stirring tank through the liquid outlet pipe, and the inner cavity top of the aloe stirring tank is provided with a stirring structure;

[0072] The stirring structure comprises a first main driving gear and an inner gear ring, wherein the inner gear ring is fixedly connected to the top of the inner cavity of the aloe stirring tank, and the inner gear ring is meshed with multiple sets of second driven gears, and the bottoms of the multiple sets of second driven gears are all fixedly connected to the first stirring shaft, and the first stirring shaft is fixedly connected to multiple sets of first stirring rods;

[0073] The same first main driving gear is meshed between the multiple sets of second driven gears, the bottom of the first main driving gear is fixedly connected to a second stirring shaft, the second stirring shaft is fixedly connected to multiple sets of second stirring rods, and the first stirring rods and the second stirring rods are staggered;

[0074] The upper surfaces of the first main driving gear and the plurality of second driven gears are rotatably connected to the top of the inner cavity of the aloe mixing tank, the top of the second mixing shaft penetrates the first main driving gear and the aloe mixing tank and extends outside, a third driving motor is arranged on the top of the aloe mixing tank, the output shaft of the third driving motor is fixedly connected to the second mixing shaft, the upper surface of the aloe mixing tank is rotatably connected to the second main driving gear and the auxiliary transmission gear respectively, the second main driving gear and the auxiliary transmission gear are meshed, and the second main driving gear is sleeved on the second mixing shaft, the upper surface of the auxiliary transmission gear is fixedly connected to the docking shaft, the bottom of the first rotating shaft of the second driving gear is fixedly connected to the top of the docking shaft;

[0075] One side of the bottom of the aloe mixing tank is connected with a drain pipe.

[0076] In step S43, during the enzymatic hydrolysis, pectinase is first added, and the amount of pectinase added is 0.08-0.12% of the mass of the aloe leaves after the treatment in step S41, and the reaction is carried out for 100-120 minutes;

[0077] Then, add acid cellulase, wherein the amount of the acid cellulase added is 0.08-0.12% of the mass of the aloe leaves after treatment in step S41, and react for 70-90 minutes;

[0078] Finally, neutral protease is added, and the amount of the neutral protease added is also 0.08-0.12% of the mass of the aloe leaves after treatment in step 431, and the reaction is carried out for 50-70 minutes.

[0079] In another aspect, the present invention provides a use of a composition for constipation, for alleviating the symptoms of constipation.

[0080] Compared with the prior art, the present invention has the following beneficial effects:

[0081] 1. The present invention uses advanced processes such as supercritical extraction, vacuum freeze drying, and ultrafine grinding to maximize the extraction and retention of effective ingredients such as dietary fiber, polysaccharides, enzymes, etc. in raw materials such as pumpkin, Poria cocos, Tremella fuciformis, and aloe vera. These ingredients have a significant effect on improving constipation. At the same time, the present invention uses a composite lactic acid bacteria fermentation agent to ferment pumpkin powder, which not only increases the probiotic content in the pumpkin powder, but also improves the biological activity of the nutrients in the pumpkin through the fermentation process, which is helpful for the balance of intestinal flora and the recovery of intestinal function. The composition of the present invention combines pumpkin powder, Poria cocos powder, Tremella fuciformis powder, aloe vera, and other raw materials. The powder and prebiotics are scientifically matched: pumpkin powder is rich in dietary fiber, which helps to promote intestinal peristalsis; Poria powder has the effect of strengthening the spleen and removing dampness; Tremella powder is rich in colloid and can lubricate the intestine; aloe-emodin and other ingredients in aloe powder can stimulate intestinal wall peristalsis and promote defecation; prebiotics help to regulate the balance of intestinal flora and improve the intestinal environment; the various ingredients can produce a synergistic effect and work together on the intestine to promote intestinal peristalsis, increase stool volume and moisture, and thus effectively relieve constipation symptoms; moreover, all raw materials of the present invention are selected from natural ingredients, without chemical additives, safe and non-toxic and non-side effects, and suitable for long-term consumption.

[0082] 2. The present invention not only relieves the symptoms of constipation, but also improves the overall intestinal health level by regulating intestinal flora, improving the intestinal environment, etc., and also has a positive effect in regulating intestinal function, enhancing immunity, etc.

[0083] 3. When preparing pumpkin powder, the present invention ensures the freshness and pollution-freeness of pumpkin raw materials through material selection and cleaning, removes inedible parts, retains the nutrients in the pumpkin, and the subsequent blanching treatment helps to inactivate some enzymes and reduce the loss of nutrients in the subsequent processing process; the segmented vacuum freeze-drying technology, in the pre-freezing stage, under the low temperature condition of -20 to -30°C, the pumpkin slices can be quickly and fully frozen to form fine ice crystals, which are more likely to sublimate in the subsequent drying process, thereby reducing the drying time and improving the drying efficiency. Low-temperature pre-freezing helps to reduce the nutrients in the pumpkin. At high temperatures, some heat-sensitive nutrients such as vitamins and enzymes are easily destroyed, while low-temperature pre-freezing can effectively avoid this problem and allow the pumpkin powder to retain more nutrients; in the drying stage, under the conditions of a vacuum degree of 0.1-0.5mbar and a temperature of 40-50℃, the ice crystals in the pumpkin slices begin to sublimate into water vapor and are discharged from the system; the efficient sublimation at this stage helps to quickly remove most of the moisture in the pumpkin slices while maintaining the shape and structure of the pumpkin slices. The appropriate drying temperature and vacuum degree can reduce the oxidation reaction of the pumpkin powder during the drying process, thereby maintaining the original color and aroma of the pumpkin. In the second drying stage, under the conditions of vacuum degree of 0.1-0.5mbar and temperature of 20-30℃, the remaining water in the pumpkin slices continues to sublimate and be discharged. The low-temperature drying in this stage helps to completely remove the water in the pumpkin powder and reach the water content standard for safe storage. Through the two-stage drying process, the pumpkin powder not only removes most of the water, but also retains the natural color, aroma and nutrients of the pumpkin, which enables the pumpkin powder to maintain excellent quality in subsequent processing and application. Ultrafine grinding refines the pumpkin powder to more than 200 meshes, greatly increasing the specific surface area of ​​the powder and improving its solubility. and bioavailability, making the nutrients in the pumpkin easier to be absorbed and utilized by the human body; the fermentation process introduces a composite lactic acid bacteria starter, which, through the metabolic action of lactic acid bacteria, not only further enriches the nutritional components of the pumpkin powder, produces vitamins, short-chain fatty acids, etc., but also gives the pumpkin powder better functionality such as regulating the balance of intestinal flora and enhancing immunity. At the same time, the acidic environment generated during the fermentation process helps to inhibit the growth of harmful microorganisms and extend the shelf life of the pumpkin powder. The fermentation and subsequent drying treatment make the pumpkin powder have a better taste and texture, and it is more delicate and easy to mix with other ingredients, which improves the overall quality of the product.

[0084] 4. When preparing Poria powder, the present invention ensures the purity and appropriate particle size of the raw materials through raw material selection and crushing, laying a good foundation for the subsequent supercritical extraction process. Through supercritical extraction and subsequent separation and concentration steps, the effective ingredients in Poria, such as polysaccharides, pachymic acid, etc., can be efficiently extracted. These ingredients play an important role in improving the intestinal environment and promoting intestinal peristalsis; the ultrafine grinding technology refines the Poria powder to more than 200 meshes, greatly increasing the specific surface area of ​​the powder, making its effective ingredients easier to be absorbed and utilized by the human body, and quickly relieving constipation symptoms; the polysaccharides and other ingredients in Poria help to regulate the balance of intestinal flora, promote the growth of beneficial bacteria, and inhibit the reproduction of harmful bacteria. A good intestinal flora environment helps to improve intestinal function and relieve intestinal problems such as constipation; the effective ingredients in Poria powder can increase the moisture in the intestine, soften feces, and promote intestinal peristalsis, thereby playing a role in moisturizing the intestine and laxative; at the same time, compared with some chemical drugs, Poria powder, as a natural plant extract, has mild ingredients, is not easy to produce dependence or side effects, and is suitable for long-term consumption to maintain intestinal health.

[0085] 5. When preparing tremella powder, the tremella itself is rich in dietary fiber. After processing, the utilization rate of its dietary fiber is further improved, which helps to increase the volume and moisture of feces in the intestine, promote intestinal peristalsis, and thus relieve constipation; through enzymatic treatment, the macromolecular substances in the tremella are decomposed into small molecular substances, such as amino acids, polysaccharides, etc., which have the effects of promoting the growth of intestinal probiotics and improving the intestinal microecological environment, thereby helping to relieve constipation; pectinase, acid cellulase and neutral protease have high activities, which can more effectively decompose the macromolecular substances in the tremella, such as dietary fiber, pectin, etc., and these components are more easily absorbed and utilized by the intestine after decomposition, thereby enhancing the peristaltic function of the intestine and helping to relieve constipation; the tremella powder after ultrafine grinding has fine and uniform particles, good solubility, can be absorbed and utilized by the human body more quickly, and improves bioavailability; enzymatic treatment removes some bad flavor substances in the tremella, so that the tremella powder has better taste and flavor.

[0086] 6. When preparing aloe powder in the present invention, aloe leaves are rich in various bioactive ingredients, such as polysaccharides, amino acids, vitamins and minerals, etc., which have a positive effect on improving intestinal health; the addition of pectinase can effectively decompose the pectin component in aloe, which is the main component of plant cell walls and intercellular layers. Its decomposition helps to break the cell wall structure, making it easier to release the effective ingredients in aloe, which not only improves the extraction rate of aloe powder, but also makes the active ingredients in aloe powder more concentrated and of better quality. The decomposition of pectin and cellulose reduces the stickiness and roughness of the fibers in the aloe powder, making the taste of the final product more delicate and the color more natural, which significantly improves the application of subsequent products and consumer acceptance; the addition of acid cellulase and neutral protease further decomposes the cellulose and protein in aloe, and these enzymatic hydrolysis products often have higher biological activity, for example, certain small molecule peptides and amino acids Acid has stronger absorption and functionality in the body, which helps to improve the nutritional value and health care effect of aloe powder; enzymatic hydrolysis can decompose macromolecular substances in aloe, such as polysaccharides and cellulose, to generate small molecular components that are more easily absorbed and utilized by the human body. These small molecular components can increase the moisture and volume in the intestine, promote intestinal peristalsis, and thus relieve constipation; enzymatic hydrolysis can also effectively control the viscosity and solid content of aloe pulp, providing convenience for subsequent centrifugation, filtration, concentration and drying processes, which not only improves production efficiency, but also reduces energy consumption and production costs; during the enzymatic hydrolysis process, by precisely controlling the type, addition amount and reaction time of the enzyme, harmful substances and impurities in aloe can be effectively removed, thereby improving the safety and stability of the product; at the same time, the enzymatic hydrolysis process itself is also a gentle processing method that does not introduce exogenous chemicals, which is conducive to maintaining the natural properties and nutritional components of aloe powder.

[0087] 7. The present invention provides an aloe vera crushing and mixing machine, wherein the cleaned aloe vera is put into a feed barrel, the aloe vera is cut into small sections by a cutting structure on one side of the feed barrel, the aloe vera cut into small sections is crushed by two crushing rollers, the cut aloe vera can be evenly laid on the two crushing rollers by a provided guide structure, thereby improving the crushing efficiency, the crushed aloe vera is transported to a separation structure by a first spiral conveying blade, the aloe vera peel is separated from the aloe vera juice, the separated aloe vera juice flows into an aloe vera mixing tank through a liquid outlet pipe, the aloe vera juice is further stirred, and the obtained aloe vera slurry is more delicate; the aloe vera is put into the feed barrel, and the aloe vera is stirred by itself. The second driving motor drives the cutting blade to rotate through the rotating shaft, so as to cut the aloe in the feeding barrel into segments. The crushing roller connected with the main rotating rod drives the main rotating rod to rotate synchronously when rotating. The main rotating rod drives the auxiliary rotating rod to rotate synchronously under the action of the fourth transmission belt. The auxiliary rotating rod drives the cam wheel to rotate. The cam wheel will push the top seat upward through the roller during the rotation process, and then push the lifting plate upward. The lifting plate slides upward along the slide groove. While sliding upward, it will apply an upward pulling force to the supporting plate through the transfer rod, so that one end of the supporting plate uses the pin shaft as the rotating fulcrum, and the other end of the supporting plate is rotated with the pin shaft as the fulcrum. As one end of the transfer rod moves upward, the support plate is in an inclined state, and the cut aloe vera slides along the inclined surface onto the two crushing rollers, thereby preventing the aloe vera from clogging the bottom of the feed barrel and affecting the crushing efficiency; when the first rotating shaft connected to the second driving gear rotates, it drives the other first rotating shaft to rotate in the same direction through the first transmission belt, and the belt sleeve on the first transmission belt moves the insert disk, and the insert disk drives the claw to move, thereby making the claw located in the second through-hole move in the direction away from the feed barrel, thereby pushing the aloe vera in the direction away from the feed barrel, so that the aloe vera is evenly dispersed on the two crushing rollers, and the crushing of the aloe vera is improved. The invention can improve efficiency and further reduce the risk of aloe vera blocking the feed barrel; when the first rotating shaft connected to the second driving gear rotates, the adjusting gear is driven to rotate through meshing action, and at the same time, under the meshing action, the rotation direction of the adjusting gear is opposite to the rotation direction of the second driving gear, so that the adjusting gear applies a rotation force opposite to the rotation direction of the second driving gear to a first rotating shaft in the dustproof protective shell away from the second driving gear through the second transmission belt, so that the pusher claw in the dustproof protective shell away from the second driving gear also moves in the direction away from the feed barrel; and the dustproof protective shell pushes the aloe vera in the same direction;As the crushed aloe vera is continuously discharged, the second spiral conveying blade will continuously squeeze the second spiral conveying blade. During the squeezing process, the juice of the crushed aloe vera will flow into the collection frame through the filter part, and the aloe vera residue will be continuously transported in the direction close to the slide by the second spiral conveying blade. As the aloe vera residue between the second spiral conveying blade and the slide increases, the aloe vera residue will exert pressure on the slide and push the slide to slide along the side close to the discharge shell. When the slide slides to the top of the bottom opening of the discharge shell, the aloe vera residue will be discharged from the bottom opening of the discharge shell to achieve dry and wet separation; the first stirring rod and the second stirring rod are staggered, further increasing the contact area between the first stirring rod and the second stirring rod and the aloe vera pulp, improving the stirring efficiency, and making the stirred aloe vera pulp more delicate. ; BRIEF DESCRIPTION OF THE DRAWINGS

[0088] Figure 1 The overall three-dimensional schematic diagram of the aloe vera crushing and mixing machine provided by the present invention;

[0089] Figure 2 A three-dimensional schematic diagram of the aloe vera crushing and mixing machine provided by the present invention from another perspective;

[0090] Figure 3 A schematic diagram of the interior of a protective frame in the aloe vera crushing and mixing machine provided by the present invention;

[0091] Figure 4 for Figure 3 A local enlarged schematic diagram of the middle A;

[0092] Figure 5 An exploded schematic diagram of the pulverizing protective housing, the separation structure and the collection frame in the aloe vera pulverizing and blending machine provided by the present invention;

[0093] Figure 6 A cutaway diagram of a pulverizing protective housing in the aloe pulverizing and blending machine provided by the present invention;

[0094] Figure 7 A cross-sectional view of the crushing protection housing of the aloe crushing mixer provided by the present invention from another perspective;

[0095] Figure 8 A cross-sectional view of a feed barrel in the aloe vera crushing and mixing machine provided by the present invention;

[0096] Fig. 9 An exploded schematic diagram of the grinding roller, the lifting plate, the supporting plate, the fixed shaft sleeve and the pin shaft in the aloe vera grinding and mixing machine provided by the present invention;

[0097] Fig.10 for Fig. 9 A partial enlarged schematic diagram of point B in the middle;

[0098] Fig.11A schematic diagram of a grinding protection shell and a guide structure in the aloe vera grinding and mixing machine provided by the present invention;

[0099] Fig.12 It is a schematic diagram of the first rotating shaft, the first transmission belt, the belt cover, and the extension plate of the aloe vera crushing and mixing machine provided in the present invention;

[0100] Fig.13 An exploded schematic diagram of an insert plate, a pusher claw, a sliding groove, a sliding sleeve, an ejector rod, a first compression spring and a docking member in the aloe vera crushing and mixing machine provided by the present invention;

[0101] Fig.14 A schematic diagram of the state when the claw of the aloe vera crushing and mixing machine provided by the present invention is located at the second penetration opening;

[0102] Fig.15 A schematic diagram of the state of the aloe vera crushing and mixing machine provided by the present invention when the claws are retracted into the dustproof protective housing;

[0103] Fig.16 A cross-sectional view of a separation protection shell and a collection frame in the aloe vera crushing and mixing machine provided by the present invention;

[0104] Fig.17 A schematic diagram of a stirring structure in an aloe vera crushing and stirring machine provided by the present invention;

[0105] Fig.18 The present invention provides a flow chart of a composition for constipation.

[0106] In the figure: 1, protection frame; 2, feed barrel; 3, crushing protection shell; 4, first conveying screw rod; 5, crushing roller; 6, bite teeth; 7, aloe mixing tank; 8, liquid outlet pipe; 9, first spiral conveying blade; 10, first discharge port; 11, first driving gear; 12, first driven gear; 13, first driving motor; 14, third transmission belt; 15, cutting disc; 16, lifting plate; 17, slide; 18, tool installation Groove; 19, first through-hole; 20, transfer rod; 21, support plate; 22, fixed shaft sleeve; 23, pin shaft; 24, second drive motor; 25, top seat; 26, roller; 27, main rotating rod; 28, auxiliary rotating rod; 29, fourth transmission belt; 30, convex top wheel; 31, baffle; 32, second through-hole; 33, first rotating shaft; 34, first transmission belt; 35, belt cover; 36, insert plate; 37, push claw; 38, sliding joint slot; 39, sleeve; 40, ejector rod; 41, first compression spring; 42, docking member; 43, extension plate; 44, turning gear; 45, second driving gear; 46, rotating rod; 47, second transmission belt; 48, avoidance groove; 49, separation protection shell; 50, second conveying spiral rod; 51, discharge port; 52, second spiral conveying blade; 53, filter; 54, discharge shell; 55, limit rod; 56, slide; 57 , second pressure spring; 58, fifth transmission belt; 59, collection frame; 60, inclined surface; 61, first main drive gear; 62, inner gear ring; 63, second driven gear; 64, first stirring shaft; 65, first stirring rod; 66, second stirring shaft; 67, second stirring rod; 68, third drive motor; 69, second main drive gear; 70, auxiliary transmission gear; 71, docking shaft; 72, drain pipe; 73, dustproof protective shell. DETAILED DESCRIPTION

[0107] Example 1

[0108] like Figure 1-17 As shown, an aloe vera crushing mixer comprises a protection frame 1 and a crushing structure installed inside the protection frame 1, one side of the protection frame 1 is connected with a feed barrel 2, one side of the feed barrel 2 is provided with a cutting structure, and the cutting structure is used to cut the aloe vera into segments, the crushing structure comprises a crushing protection shell 3, a first conveying screw rod 4 and two crushing rollers 5, the interior of the feed barrel 2 is connected with the interior of the crushing protection shell 3, the first conveying screw rod 4 and the two crushing rollers 5 are both located inside the crushing protection shell 3 and both ends are rotatably connected to the side wall of the crushing protection shell 3, a plurality of meshing teeth 6 are provided on the roller bodies of the two crushing rollers 5, the first conveying screw rod 4 is located below the two crushing rollers 5, and the first conveying screw rod 4 is fixedly connected with a first spiral conveying blade 9;

[0109] The crushing structure is provided with a guide structure for guiding the movement of the aloe vera, and the bottom of the crushing structure is provided with a separation structure for separating the crushed aloe vera into dry and wet parts. One side of the separation structure is connected to an aloe vera stirring tank 7, and the separation structure is connected to the aloe vera stirring tank 7 through a liquid outlet pipe 8;

[0110] The meshing teeth 6 on the roller bodies of the two crushing rollers 5 are staggered to further improve the crushing efficiency of the aloe vera. The first conveying screw rod 4 is located at the center below the two crushing rollers 5. The outer side wall of the first spiral conveying blade 9 is slidably connected to the bottom of the inner cavity of the crushing protection shell 3. The bottom of the crushing protection shell 3 is provided with a first discharge port 10, and the first discharge port 10 is located at the bottom of one side of the first conveying screw rod 4.

[0111] The same end of the first conveying screw rod 4 and the two crushing rollers 5 penetrates the crushing protection shell 3 and extends outside, and the roller bodies of the two crushing rollers 5 are respectively fixedly connected with a first driving gear 11 and a first driven gear 12. A first driving motor 13 is arranged on the side of the protection frame 1 close to the first driving gear 11, and the output shaft of the first driving motor 13 penetrates the protection frame 1 and is fixedly connected to the crushing rollers 5 connected with the first driving gear 11;

[0112] The first conveying screw rod 4 is connected to one of the crushing rollers 5 through a third transmission belt 14 .

[0113] Preferably, the cutting structure includes a cutting disc 15 and a lifting plate 16, a slide groove 17 and a tool installation groove 18 are provided on the same side of the inside of the feed barrel 2, the lifting plate 16 is slidably connected in the slide groove 17 and the bottom thereof abuts against the upper surface of the crushing protection shell 3, the tool installation groove 18 is located above the slide groove 17, and the cutting disc 15 is rotatably connected in the tool installation groove 18;

[0114] The bottom of the lifting plate 16 is provided with a first through hole 19, and the two sides of the first through hole 19 are fixedly connected with transfer rods 20, and the two transfer rods 20 are rotatably connected with the same support plate 21, and the upper surface of the crushing protection shell 3 on the side close to the feed barrel 2 is symmetrically fixedly connected with a fixed shaft sleeve 22, and the opposite side surfaces of the two fixed shaft sleeves 22 are fixedly connected with a pin shaft 23, and the free end of the support plate 21 is rotatably connected with the two pin shafts 23;

[0115] A second drive motor 24 is disposed at the bottom of one side of the crushing protection housing 3 close to the feed barrel 2, and an output shaft of the second drive motor 24 is fixedly connected to the bottom of the cutting disc 15;

[0116] A top seat 25 is fixedly connected to one side of the lifting plate 16, and a roller 26 is rotatably connected to the bottom of the top seat 25. A main rotating rod 27 is fixedly connected to one end of one of the crushing rollers 5 close to the feed barrel 2, and a secondary rotating rod 28 is fixedly connected to one side of the crushing protection shell 3. The top seat 25, the main rotating rod 27 and the secondary rotating rod 28 are located on the same side, and the main rotating rod 27 and the secondary rotating rod 28 are connected by a fourth transmission belt 29.

[0117] The auxiliary rotating rod 28 is fixedly connected with a convex top wheel 30, and the roller 26 is in rolling contact with the outer side surface of the convex top wheel 30;

[0118] A baffle 31 is symmetrically arranged on the upper surface of the crushing protection shell 3 close to the feed barrel 2 to prevent the cut aloe from slipping out from between the crushing protection shell 3 and the feed barrel 2, and to avoid the aloe from clogging the bottom of the feed barrel 2 and affecting the crushing efficiency. The baffle 31 is located on both sides of the support plate 21.

[0119] Preferably, the guide structure includes a dustproof protective shell 73, which is symmetrically installed on both sides of the top of the crushing protective shell 3, and the two opposite sides of the dustproof protective shells 73 are each provided with a second through-hole 32, and the first rotating shaft 33 is rotatably connected to the two sides of the crushing protective shell 3, and the two first rotating shafts 33 are sleeved with the same first transmission belt 34, and a plurality of belt sleeves 35 are fixedly connected to the outer wall of the first transmission belt 34, and the upper surfaces of the plurality of belt sleeves 35 are fixedly connected to the insertion disk 36, and the outer side surface of the insertion disk 36 is rotatably connected to the pusher claw 37, and the pusher claw 37 is located in the second through-hole 32;

[0120] The upper surface of the insert plate 36 is provided with a sliding groove 38 in a circumferential manner, and a sliding sleeve 39 adapted to the sliding groove 38 is embedded in the sliding groove 38. The sliding sleeve 39 is hollow inside and has an open top. An ejector rod 40 and a first compression spring 41 are arranged inside the sliding sleeve 39. The first compression spring 41 is sleeved on the rod body of the ejector rod 40, and the two ends of the first compression spring 41 are respectively fixedly connected to the ejector rod 40 and one side of the inner part of the sliding sleeve 39. One end of the ejector rod 40 passes through the sliding sleeve 39 and extends outside.

[0121] A docking piece 42 is fixedly connected to the upper surface of the pusher claw 37 , and the other end of the docking piece 42 is fixedly connected to the upper surface of one side of the ejection rod 40 .

[0122] Preferably, an extension plate 43 is provided on one side of the crushing protection housing 3, and a direction-adjusting gear 44 is rotatably connected to the upper surface of the extension plate 43, wherein the bottom of one of the first rotating shafts 33 passes through the dust-proof protection housing 73 and extends outside, and a second driving gear 45 is fixedly connected to the shaft body of the extended first rotating shaft 33, and the direction-adjusting gear 44 is meshed with the second driving gear 45;

[0123] The upper surface of the steering gear 44 is fixedly connected to a rotating rod 46, and a second transmission belt 47 is sleeved on the rod of the rotating rod 46. The rotating rod 46 is transmission-connected to a first rotating shaft 33 in a dustproof protective housing 73 away from the second driving gear 45 through the second transmission belt 47.

[0124] The outer side walls of the two dust-proof protective shells 73 close to the feeding barrel 2 are both provided with avoidance grooves 48;

[0125] The separation structure includes a separation protection shell 49 and a second conveying screw rod 50, the separation protection shell 49 is located below the crushing protection shell 3 and a discharge port 51 is provided on one side of the top of the separation protection shell 49, the discharge port 51 is communicated with the first discharge port 10, the second conveying screw rod 50 is rotatably connected to the inside of the separation protection shell 49, a second spiral conveying blade 52 is fixedly connected to the second conveying screw rod 50, a filter part 53 is provided at the bottom of the separation protection shell 49, and the outer side wall of the second spiral conveying blade 52 is slidably connected to the inner wall of the filter part 53;

[0126] A discharge housing 54 is fixedly sleeved on one side of the separation protection housing 49, the bottom of the discharge housing 54 is open, and the bottom of the protection frame 1 is provided with an opening connected to the discharge housing 54;

[0127] A limiting rod 55 is fixedly connected to one side of the inner wall of the discharge housing 54, and a slide plate 56 is slidably connected to the limiting rod 55. A second pressure spring 57 is sleeved on the limiting rod 55. The second pressure spring 57 is located between the slide plate 56 and the discharge housing 54, and the two ends of the second pressure spring 57 are fixedly connected to the slide plate 56 and the discharge housing 54 respectively.

[0128] The end of the second conveying screw rod 50 away from the feeding barrel 2 passes through the separation protection shell 49 and extends outside. The second conveying screw rod 50 is connected to the first conveying screw rod 4 through the fifth transmission belt 58. When the first conveying screw rod 4 rotates, it will drive the second conveying screw rod 50 to rotate synchronously through the fifth transmission belt 58.

[0129] The bottom of the separation protection shell 49 is fixedly connected to a collection frame 59, the bottom of the inner cavity of the collection frame 59 is provided with an inclined surface 60, one side of the collection frame 59 is connected to a liquid outlet pipe 8, the collection frame 59 is connected to the aloe mixing tank 7 through the liquid outlet pipe 8, and the inner cavity top of the aloe mixing tank 7 is provided with a stirring structure;

[0130] The stirring structure includes a first main driving gear 61 and an inner gear ring 62, wherein the inner gear ring 62 is fixedly connected to the top of the inner cavity of the aloe stirring tank 7, and the inner gear ring 62 is meshed with multiple sets of second driven gears 63, and the bottoms of the multiple sets of the second driven gears 63 are all fixedly connected to a first stirring shaft 64, and the first stirring shaft 64 is fixedly connected to multiple sets of first stirring rods 65;

[0131] The plurality of second driven gears 63 are meshed with the same first main driving gear 61. The bottom of the first main driving gear 61 is fixedly connected with a second stirring shaft 66. The second stirring shaft 66 is fixedly connected with a plurality of second stirring rods 67. The first stirring rod 65 and the second stirring rod 67 are staggered, which further increases the contact area between the first stirring rod 65 and the second stirring rod 67 and the aloe juice, improves the stirring efficiency, and makes the stirred aloe juice more delicate.

[0132] The upper surfaces of the first main driving gear 61 and the plurality of second driven gears 63 are rotatably connected to the top of the inner cavity of the aloe mixing tank 7. The top of the second stirring shaft 66 penetrates the first main driving gear 61 and the aloe mixing tank 7 and extends outside. A third driving motor 68 is provided on the top of the aloe mixing tank 7. The output shaft of the third driving motor 68 is fixedly connected to the second stirring shaft 66. The upper surface of the aloe mixing tank 7 is rotatably connected to the second main driving gear 69 and the auxiliary transmission gear 70 respectively. The second main driving gear 69 is meshed with the auxiliary transmission gear 70, and the second main driving gear 69 sleeve It is arranged on the second stirring shaft 66, the upper surface of the auxiliary transmission gear 70 is fixedly connected to the docking shaft 71, and the bottom of the first rotating shaft 33 fixedly connected to the second driving gear 45 is fixedly connected to the top of the docking shaft 71; the second stirring shaft 66 will drive the second main driving gear 69 to rotate while rotating, and under the meshing action, the second main driving gear 69 drives the auxiliary transmission gear 70 to rotate, and the auxiliary transmission gear 70 drives the first rotating shaft 33 fixedly connected to the second driving gear 45 to rotate through the docking shaft 71, thereby providing power for the guide structure, and a drain pipe 72 is connected to one side of the bottom of the aloe vera stirring tank 7.

[0133] The working process of aloe vera crushing blender:

[0134] Put the aloe vera into the feed barrel 2, and under the gravity of the aloe vera itself, its bottom will abut against the upper surface of the support plate 21, and the second drive motor 24 drives the cutting blade 15 to rotate through the rotating shaft to start cutting the aloe vera in the feed barrel 2, and the crushing roller 5 connected to the main rotating rod 27 will drive the main rotating rod 27 to rotate synchronously when rotating, and the main rotating rod 27 drives the auxiliary rotating rod 28 to rotate synchronously under the action of the fourth transmission belt 29, and the auxiliary rotating rod 28 drives the cam wheel 30 to rotate, and the cam wheel During the rotation, the top seat 25 is lifted upward by the roller 26, and then the lifting plate 16 is lifted upward. The lifting plate 16 slides upward along the slide groove 17. While sliding upward, an upward pulling force is applied to the support plate 21 through the transfer rod 20, so that one end of the support plate 21 uses the pin shaft 23 as a rotation fulcrum, and the other end moves upward with the transfer rod 20. At this time, the support plate 21 is in an inclined state, and the cut aloe slides along the inclined surface 60 onto the two crushing rollers 5.

[0135] The first driving motor 13 drives the first driving gear 11 to rotate through the output shaft. Under the meshing action, the first driving gear 11 drives the first driven gear 12 to rotate, and then drives the meshing teeth 6 on the two crushing rollers 5 to crush the aloe cut into small sections. During the crushing process, the first rotating shaft 33 connected to the second driving gear 45 drives the other first rotating shaft 33 to rotate in the same direction through the first transmission belt 34 when rotating, and the belt sleeve 35 on the first transmission belt 34 The disk 36 moves, and the disk 36 drives the claw 37 to move, and then the claw 37 located in the second through-hole 32 moves in a direction away from the feed barrel 2, and then the aloe is pushed in the direction away from the feed barrel 2, so that the aloe is evenly dispersed on the two crushing rollers 5, thereby improving the crushing efficiency of the aloe;

[0136] When the first rotating shaft 33 connected to the second driving gear 45 rotates, it drives the adjustment gear 44 to rotate through meshing. At the same time, under the meshing action, the rotation direction of the adjustment gear 44 is opposite to the rotation direction of the second driving gear 45, so that the adjustment gear 44 applies a rotation force opposite to the rotation direction of the second driving gear 45 to a first rotating shaft 33 in the dustproof protective housing 73 away from the second driving gear 45 through the second transmission belt 47, so that the pusher 37 in the dustproof protective housing 73 away from the second driving gear 45 is also moved in the direction away from the feed barrel 2.

[0137] When the pusher claw 37 moves to the maximum distance from the feed barrel 2, the pusher claw 37 extends from the second through-hole 32 and moves to the inside of the dust-proof protection shell 73 and away from the side of the second through-hole 32. During the movement, the dust-proof protection shell 73 will squeeze the outer edge of the pusher claw 37, and the pusher claw 37 will rotate on the outside of the insertion plate 36, and then the pusher claw 37 will retract into the dust-proof protection shell 73. During the retraction of the pusher claw 37, the pusher claw 37 squeezes the ejector rod 40 through the docking piece 42, so that one end of the ejector rod 40 passes through the sliding sleeve 39. During the ejection process of the ejector rod 40, the first compression spring 41 will be compressed, and the ejector rod 40 will be driven to retract under the action of the first transmission belt 34 and the belt sleeve 35. The pusher claw 37 in the dustproof protection shell 73 moves in the direction close to the feed barrel 2. When the pusher claw 37 passes through the avoidance groove 48, the contact point between the dustproof protection shell 73 and the pusher claw 37 gradually moves along the outer side of the pusher claw 37 to the free end surface of the pusher claw 37. During the movement, the first compression spring 41 in the compressed state will be gradually stretched and reset. While the first compression spring 41 is reset, a thrust is applied to the ejection rod 40, so that the ejection rod 40 extending out of the sliding sleeve 39 is gradually reset. When the pusher claw 37 completely stops contacting the dustproof protection shell 73, the first compression spring 41 is completely reset and pushes the ejection rod 40 to be completely reset, thereby resetting the pusher claw 37 in the retracted state.

[0138] When the crushing roller 5 rotates, it will drive the first conveying screw rod 4 to rotate synchronously through the third transmission belt 14, so that the first spiral conveying blade 9 starts to rotate to transport the crushed aloe. The first spiral conveying blade 9 discharges the crushed aloe into the discharge port 51 through the first discharge port 10, and flows into the second spiral conveying blade 52 through the discharge port 51. The second spiral conveying blade 52 will convey the crushed aloe in the direction close to the slide 56. As the crushed aloe is continuously discharged, the second spiral conveying blade 52 will The blades 52 are constantly squeezed, and during the squeezing process, the juice of the crushed aloe vera will flow into the collecting frame 59 through the filter portion 53, and the aloe vera residue will be continuously transported along the direction close to the slide 56 by the second spiral conveying blade 52. As the aloe vera residue between the second spiral conveying blade 52 and the slide 56 increases, the aloe vera residue will exert pressure on the slide 56 and push the slide 56 to slide along the side close to the discharge housing 54. When the slide slides to the top of the bottom opening of the discharge housing 54, the aloe vera residue will be discharged from the bottom opening of the discharge housing 54.

[0139] The aloe slurry in the collecting frame 59 flows into the liquid outlet pipe 8 along the inclined surface 60, and flows into the aloe stirring tank 7 through the liquid outlet pipe 8. The third driving motor 68 drives the first main driving gear 61 to rotate. Under the meshing action, the first main driving gear 61 drives multiple groups of second driven gears 63 to rotate. The first main driving gear 61 drives multiple groups of second stirring rods 67 to rotate through the second stirring shaft 66; the second driven gear 63 drives multiple groups of first stirring rods 65 to rotate through the first stirring shaft 64; the aloe slurry is further stirred, and the stirred aloe can be discharged through the discharge pipe 72 for collection by the staff.

[0140] Example 2

[0141] A composition for constipation, comprising 130 parts of pumpkin powder, 30 parts of Poria powder, 40 parts of Tremella powder, 80 parts of aloe powder, and 80 parts of prebiotics. The preparation method of the composition for constipation is as follows:

[0142] Step 1: Prepare pumpkin powder

[0143] S11. Material selection and cleaning: select old pumpkins that are highly mature and not rotten or deteriorated, remove the pumpkin stem and stalk, clean and drain, soak in disinfectant, and then clean with drinking water three times;

[0144] S12, slicing and blanching: cutting the washed pumpkin into slices, and then blanching;

[0145] S13, vacuum freeze drying: vacuum freeze drying the blanched pumpkin slices;

[0146] S14, ultrafine grinding: ultrafine grinding the vacuum freeze-dried pumpkin slices to a size of more than 200 meshes;

[0147] S15, fermentation: the ultrafinely crushed pumpkin powder is inoculated into a composite lactic acid bacteria starter, and fermented at 18° C. for 7 days until the final pH value of the fermentation is 3.0;

[0148] S16, drying: drying at 40° C. to make the water content less than or equal to 5%, to obtain pumpkin powder;

[0149] Step 2: Prepare Poria powder

[0150] S21, raw material preparation: select dry, mildew-free Poria cocos and crush it into 20 mesh;

[0151] S22, supercritical extraction: subjecting the crushed Poria cocos powder to supercritical extraction;

[0152] S23, separation and concentration: after the supercritical extraction is completed, an extract containing the effective ingredients of Poria cocos is separated and concentrated to obtain a concentrated Poria cocos extract;

[0153] S24, vacuum freeze drying: vacuum freeze drying the concentrated Poria cocos extract until the water content is less than or equal to 5%;

[0154] S25, ultrafine grinding: ultrafine grinding the vacuum-dried Poria cocos to a size of more than 200 meshes to obtain Poria cocos powder;

[0155] Step 3: Prepare Tremella Powder

[0156] S31, raw material preparation: select dry, mildew-free Tremella fuciformis and crush it to more than 100 mesh;

[0157] S32, suspension preparation: mixing the crushed Tremella fuciformis with water to form a suspension;

[0158] S33, pH adjustment: add citric acid to the suspension to adjust the pH to 4;

[0159] S34, enzymatic hydrolysis: at a temperature of 50° C., pectinase, acid cellulase, and neutral protease are sequentially added to the suspension for enzymatic hydrolysis;

[0160] S35, filtering and drying: After the enzymatic hydrolysis is completed, the suspension is centrifuged, the liquid component is taken, concentrated, dried, and ultrafinely ground to more than 200 meshes to obtain Tremella powder;

[0161] Step 4: Prepare aloe vera powder

[0162] S41. Raw material preparation: select fresh aloe leaves free of pests and diseases, wash and remove impurities;

[0163] S42, cutting and crushing: cutting the cleaned aloe leaves into blocks of appropriate size using the aloe crushing and blending machine provided in Example 1, and then crushing and pulping them using the aloe crushing and blending machine provided in Example 1 until fine aloe pulp is formed;

[0164] S43, enzymatic hydrolysis: adding pectinase, acid cellulase, and neutral protease to the aloe pulp in sequence at a temperature of 40° C. for enzymatic hydrolysis;

[0165] S44, centrifugation and filtration: after the enzymatic hydrolysis is completed, the aloe slurry is centrifuged to obtain a liquid component, and the liquid component is filtered, concentrated, and dried;

[0166] S45, ultrafine grinding: ultrafine grinding to more than 200 meshes to obtain aloe powder;

[0167] Step 5: Prepare a composition for constipation

[0168] 130 parts of pumpkin powder prepared in steps 1 to 5, 30 parts of Poria powder, 40 parts of Tremella powder, 80 parts of aloe powder and 80 parts of prebiotics are mixed evenly to prepare capsules to obtain a composition for constipation.

[0169] Preferably, in step 1, when preparing pumpkin powder:

[0170] In step S12, the washed pumpkin is cut into slices of 5 cm x 5 cm x 2 cm; the blanching treatment is to blanch the pumpkin slices in 90° C. boiling water for 2 minutes;

[0171] Step S13, the vacuum freeze drying process is as follows:

[0172] Pre-freezing stage: Freeze at -20℃ for 10 hours;

[0173] Drying stage 1: Drying at a vacuum degree of 0.1 mbar and a temperature of 40°C for 8 hours;

[0174] Drying stage 2: Drying at a vacuum degree of 0.1 mbar and a temperature of 20°C for 5 hours.

[0175] In step S15, the inoculation amount of the composite lactic acid bacteria fermentation agent is 1% of the weight of the pumpkin powder, and the composite lactic acid bacteria fermentation agent is obtained by compounding Lactobacillus plantarum, Lactobacillus restiger and Lactobacillus brevis in a mass ratio of 2:1:1.

[0176] Preferably, in step 2, when preparing Poria cocos powder:

[0177] In step S22, the specific method of supercritical extraction is: placing the crushed Poria cocos powder in a supercritical extraction device, setting the extraction conditions to a temperature of 35° C., a pressure of 20 MPa, an extraction time of 2 h, and introducing carbon dioxide as an extractant for supercritical extraction;

[0178] In step S24, the specific method of vacuum freeze drying is: after pre-freezing the concentrated Poria cocos extract at -40 for 8 hours, sublimation drying is carried out under the conditions of vacuum degree of 10 Pa and temperature of 30° C. to make the water content less than or equal to 5%.

[0179] Preferably, in step 3, when preparing Tremella powder:

[0180] In step S32, the crushed Tremella fuciformis is mixed with water in a mass ratio of 1:5 to form a suspension;

[0181] In step S34, during the enzymatic hydrolysis, pectinase is first added, and the amount of pectinase added is 0.08% of the mass of the Tremella fuciformis treated in step S31, and the reaction is carried out for 80 minutes;

[0182] Then, acid cellulase is added, wherein the amount of the acid cellulase added is 0.08% of the mass of the Tremella fuciformis after treatment in step S31, and the reaction is carried out for 60 minutes;

[0183] Finally, neutral protease is added, and the amount of the neutral protease added is also 0.08% of the mass of the Tremella after treatment in step S31, and the reaction is carried out for 40 minutes.

[0184] Preferably, in step 4, when preparing aloe vera powder:

[0185] In step S43, during the enzymatic hydrolysis, pectinase is first added, and the amount of pectinase added is 0.08% of the mass of the aloe leaves after the treatment in step S41, and the reaction is carried out for 100 minutes;

[0186] Then, acid cellulase is added, wherein the amount of the acid cellulase added is 0.08% of the mass of the aloe leaves after treatment in step S41, and the reaction is carried out for 70 minutes;

[0187] Finally, neutral protease is added, and the amount of the neutral protease added is also 0.08% of the mass of the aloe leaves after treatment in step 431, and the reaction is carried out for 50 minutes.

[0188] Example 3

[0189] A composition for constipation, comprising 140 parts of pumpkin powder, 35 parts of Poria powder, 50 parts of Tremella powder, 90 parts of aloe powder, and 90 parts of prebiotics. The preparation method of the composition for constipation is as follows:

[0190] Step 1: Prepare pumpkin powder

[0191] S11. Material selection and cleaning: select old pumpkins that are highly mature and not rotten or deteriorated, remove the pumpkin stem and handle, wash and drain, soak in disinfectant, and then wash with drinking water 4 times;

[0192] S12, slicing and blanching: cutting the washed pumpkin into slices, and then blanching;

[0193] S13, vacuum freeze drying: vacuum freeze drying the blanched pumpkin slices;

[0194] S14, ultrafine grinding: ultrafine grinding the vacuum freeze-dried pumpkin slices to a size of more than 200 meshes;

[0195] S15, fermentation: the ultrafinely crushed pumpkin powder is inoculated into a composite lactic acid bacteria starter, and fermented at 25° C. for 15 days until the final pH value of the fermentation is 3.5;

[0196] S16, drying: drying at 60° C. to make the water content less than or equal to 5%, to obtain pumpkin powder;

[0197] Step 2: Prepare Poria powder

[0198] S21, raw material preparation: select dry, non-moldy Poria cocos and crush it into 60 mesh;

[0199] S22, supercritical extraction: subjecting the crushed Poria cocos powder to supercritical extraction;

[0200] S23, separation and concentration: after the supercritical extraction is completed, an extract containing the effective ingredients of Poria cocos is separated and concentrated to obtain a concentrated Poria cocos extract;

[0201] S24, vacuum freeze drying: vacuum freeze drying the concentrated Poria cocos extract until the water content is less than or equal to 5%;

[0202] S25, ultrafine grinding: ultrafine grinding the vacuum-dried Poria cocos to a size of more than 200 meshes to obtain Poria cocos powder;

[0203] Step 3: Prepare Tremella Powder

[0204] S31, raw material preparation: select dry, mildew-free Tremella fuciformis and crush it to more than 100 mesh;

[0205] S32, suspension preparation: mixing the crushed Tremella fuciformis with water to form a suspension;

[0206] S33, pH adjustment: add citric acid to the suspension to adjust the pH to 5;

[0207] S34, enzymatic hydrolysis: at a temperature of 60° C., pectinase, acid cellulase, and neutral protease are sequentially added to the suspension for enzymatic hydrolysis;

[0208] S35, filtering and drying: After the enzymatic hydrolysis is completed, the suspension is centrifuged, the liquid component is taken, concentrated, dried, and ultrafinely ground to more than 200 meshes to obtain Tremella powder;

[0209] Step 4: Prepare aloe vera powder

[0210] S41. Raw material preparation: select fresh aloe leaves free of pests and diseases, wash and remove impurities;

[0211] S42, cutting and crushing: cutting the cleaned aloe leaves into blocks of appropriate size using the aloe crushing and blending machine provided in Example 1, and then crushing and pulping them using the aloe crushing and blending machine provided in Example 1 until fine aloe pulp is formed;

[0212] S43, enzymatic hydrolysis: adding pectinase, acid cellulase, and neutral protease to the aloe pulp in sequence at a temperature of 50° C. for enzymatic hydrolysis;

[0213] S44, centrifugation and filtration: after the enzymatic hydrolysis is completed, the aloe slurry is centrifuged to obtain a liquid component, and the liquid component is filtered, concentrated, and dried;

[0214] S45, ultrafine grinding: ultrafine grinding to more than 200 meshes to obtain aloe powder;

[0215] Step 5: Prepare a composition for constipation

[0216] 140 parts of pumpkin powder, 35 parts of Poria powder, 50 parts of Tremella powder, 90 parts of aloe powder and 90 parts of prebiotics prepared in steps 1 to 5 are mixed evenly to prepare capsules to obtain a composition for constipation.

[0217] Preferably, in step 1, when preparing pumpkin powder:

[0218] In step S12, the washed pumpkin is cut into slices of 8 cm x 8 cm x 2 cm; the blanching treatment is to blanch the pumpkin slices in 90° C. boiling water for 3 minutes;

[0219] Step S13, the vacuum freeze drying process is as follows:

[0220] Pre-freezing stage: Freeze at -30℃ for 15 hours;

[0221] Drying stage 1: Drying at a vacuum degree of 0.5 mbar and a temperature of 50°C for 10 hours;

[0222] Drying stage 2: Drying at a vacuum degree of 0.5 mbar and a temperature of 30°C for 8 hours.

[0223] In step S15, the inoculation amount of the composite lactic acid bacteria fermentation agent is 3% of the weight of the pumpkin powder, and the composite lactic acid bacteria fermentation agent is obtained by compounding Lactobacillus plantarum, Lactobacillus restiger and Lactobacillus brevis in a mass ratio of 2:1:1.

[0224] Preferably, in step 2, when preparing Poria cocos powder:

[0225] In step S22, the specific method of supercritical extraction is: placing the crushed Poria cocos powder in a supercritical extraction device, setting the extraction conditions to a temperature of 40° C., a pressure of 40 MPa, an extraction time of 4 h, and introducing carbon dioxide as an extractant for supercritical extraction;

[0226] In step S24, the specific method of vacuum freeze drying is: after pre-freezing the concentrated Poria cocos extract at -60°C for 10 hours, sublimation drying is performed under the conditions of vacuum degree of 20Pa and temperature of 50°C to make the water content less than or equal to 5%.

[0227] Preferably, in step 3, when preparing Tremella powder:

[0228] In step S32, the crushed Tremella fuciformis is mixed with water at a mass ratio of 1:10 to form a suspension;

[0229] In step S34, during the enzymatic hydrolysis, pectinase is first added, and the amount of pectinase added is 0.12% of the mass of the Tremella fuciformis treated in step S31, and the reaction is carried out for 90 minutes;

[0230] Then, acid cellulase is added, wherein the amount of the acid cellulase added is 0.12% of the mass of the Tremella fuciformis after treatment in step S31, and the reaction is carried out for 80 minutes;

[0231] Finally, neutral protease is added, and the amount of the neutral protease added is also 0.12% of the mass of the Tremella after treatment in step S31, and the reaction is carried out for 60 minutes.

[0232] Preferably, in step 4, when preparing aloe vera powder:

[0233] In step S43, during the enzymatic hydrolysis, pectinase is first added, and the amount of pectinase added is 0.12% of the mass of the aloe leaves after the treatment in step S41, and the reaction is carried out for 120 minutes;

[0234] Then, acid cellulase is added, wherein the amount of the acid cellulase added is 0.12% of the mass of the aloe leaves after treatment in step S41, and the reaction is carried out for 90 minutes;

[0235] Finally, neutral protease is added, and the amount of the neutral protease added is also 0.12% of the mass of the aloe leaves after treatment in step 431, and the reaction is carried out for 70 minutes.

[0236] Example 4

[0237] A composition for constipation, comprising 135 parts of pumpkin powder, 33 parts of Poria powder, 45 parts of Tremella powder, 85 parts of aloe powder, and 85 parts of prebiotics. The preparation method of the composition for constipation is as follows:

[0238] Step 1: Prepare pumpkin powder

[0239] S11. Material selection and cleaning: select old pumpkins that are highly mature and not rotten or deteriorated, remove the pumpkin stem and handle, wash and drain, soak in disinfectant, and then wash with drinking water 4 times;

[0240] S12, slicing and blanching: cutting the washed pumpkin into slices, and then blanching;

[0241] S13, vacuum freeze drying: vacuum freeze drying the blanched pumpkin slices;

[0242] S14, ultrafine grinding: ultrafine grinding the vacuum freeze-dried pumpkin slices to a size of more than 200 meshes;

[0243] S15, fermentation: the ultrafinely crushed pumpkin powder is inoculated into a composite lactic acid bacteria starter, and fermented at 21° C. for 10 days until the final pH value of the fermentation is 3.2;

[0244] S16, drying: drying at 45° C. to make the water content less than or equal to 5%, to obtain pumpkin powder;

[0245] Step 2: Prepare Poria powder

[0246] S21, raw material preparation: select dry, non-moldy Poria cocos and crush it into 40 mesh;

[0247] S22, supercritical extraction: subjecting the crushed Poria cocos powder to supercritical extraction;

[0248] S23, separation and concentration: after the supercritical extraction is completed, an extract containing the effective ingredients of Poria cocos is separated and concentrated to obtain a concentrated Poria cocos extract;

[0249] S24, vacuum freeze drying: vacuum freeze drying the concentrated Poria cocos extract until the water content is less than or equal to 5%;

[0250] S25, ultrafine grinding: ultrafine grinding the vacuum-dried Poria cocos to a size of more than 200 meshes to obtain Poria cocos powder;

[0251] Step 3: Prepare Tremella Powder

[0252] S31, raw material preparation: select dry, mildew-free Tremella fuciformis and crush it to more than 100 mesh;

[0253] S32, suspension preparation: mixing the crushed Tremella fuciformis with water to form a suspension;

[0254] S33, pH adjustment: add citric acid to the suspension to adjust the pH to 4;

[0255] S34, enzymatic hydrolysis: at a temperature of 55° C., pectinase, acid cellulase, and neutral protease are sequentially added to the suspension for enzymatic hydrolysis;

[0256] S35, filtering and drying: After the enzymatic hydrolysis is completed, the suspension is centrifuged, the liquid component is taken, concentrated, dried, and ultrafinely ground to more than 200 meshes to obtain Tremella powder;

[0257] Step 4: Prepare aloe vera powder

[0258] S41. Raw material preparation: select fresh aloe leaves free of pests and diseases, wash and remove impurities;

[0259] S42, cutting and crushing: cutting the cleaned aloe leaves into blocks of appropriate size using the aloe crushing and blending machine provided in Example 1, and then crushing and pulping them using the aloe crushing and blending machine provided in Example 1 until fine aloe pulp is formed;

[0260] S43, enzymatic hydrolysis: adding pectinase, acid cellulase, and neutral protease to the aloe pulp in sequence at a temperature of 45° C. for enzymatic hydrolysis;

[0261] S44, centrifugation and filtration: after the enzymatic hydrolysis is completed, the aloe slurry is centrifuged to obtain a liquid component, and the liquid component is filtered, concentrated, and dried;

[0262] S45, ultrafine grinding: ultrafine grinding to more than 200 meshes to obtain aloe powder;

[0263] Step 5: Prepare a composition for constipation

[0264] 135 parts of pumpkin powder prepared in steps 1 to 5, 33 parts of Poria powder, 45 parts of Tremella powder, 85 parts of aloe powder and 85 parts of prebiotics are mixed evenly to prepare capsules to obtain a composition for constipation.

[0265] Preferably, in step 1, when preparing pumpkin powder:

[0266] In step S12, the washed pumpkin is cut into slices of 6 cm x 6 cm x 2 cm; the blanching treatment is to blanch the pumpkin slices in 90° C. boiling water for 2.5 min;

[0267] Step S13, the vacuum freeze drying process is as follows:

[0268] Pre-freezing stage: Freeze at -25℃ for 13 hours;

[0269] Drying stage 1: Drying at a vacuum degree of 0.3 mbar and a temperature of 45°C for 9 hours;

[0270] Drying stage 2: Drying at a vacuum degree of 0.4 mbar and a temperature of 25°C for 6 hours.

[0271] In step S15, the inoculation amount of the composite lactic acid bacteria fermentation agent is 2% of the weight of the pumpkin powder, and the composite lactic acid bacteria fermentation agent is obtained by compounding Lactobacillus plantarum, Lactobacillus restiger and Lactobacillus brevis in a mass ratio of 2:1:1.

[0272] Preferably, in step 2, when preparing Poria cocos powder:

[0273] In step S22, the specific method of supercritical extraction is: placing the crushed Poria cocos powder in a supercritical extraction device, setting the extraction conditions to a temperature of 38° C., a pressure of 30 MPa, an extraction time of 3 h, and introducing carbon dioxide as an extractant for supercritical extraction;

[0274] In step S24, the specific method of vacuum freeze drying is: after pre-freezing the concentrated Poria cocos extract at -50°C for 9 hours, sublimation drying is performed under the conditions of vacuum degree of 15 Pa and temperature of 40°C to make the water content less than or equal to 5%.

[0275] Preferably, in step 3, when preparing Tremella powder:

[0276] In step S32, the crushed Tremella fuciformis is mixed with water in a mass ratio of 1:8 to form a suspension;

[0277] In step S34, during the enzymatic hydrolysis, pectinase is first added, the amount of pectinase added is 0.1% of the mass of the Tremella fuciformis treated in step S31, and the reaction is performed for 85 minutes;

[0278] Then, acid cellulase is added, wherein the amount of the acid cellulase added is 0.1% of the mass of the Tremella fuciformis after treatment in step S31, and the reaction is carried out for 70 minutes;

[0279] Finally, neutral protease is added, and the amount of the neutral protease added is also 0.1% of the mass of the Tremella after treatment in step S31, and the reaction is carried out for 50 minutes.

[0280] Preferably, in step 4, when preparing aloe vera powder:

[0281] In step S43, during the enzymatic hydrolysis, pectinase is first added, and the amount of pectinase added is 0.1% of the mass of the aloe leaves after the treatment in step S41, and the reaction lasts for 110 minutes;

[0282] Then, acid cellulase is added, wherein the amount of the acid cellulase added is 0.1% of the mass of the aloe leaves after treatment in step S41, and the reaction is carried out for 80 minutes;

[0283] Finally, neutral protease is added, and the amount of the neutral protease added is also 0.1% of the mass of the aloe leaves after treatment in step 431, and the reaction is carried out for 60 minutes.

[0284] Experimental Section

[0285] Experiment 1

[0286] Healthy mice of similar age and uniform weight were selected and divided into experimental group, positive control group, negative control group and comparison group, with 10 mice in each group.

[0287] Experimental group: administered with the constipation composition of the present invention;

[0288] Positive control group: given "Dahuang Tongbian Granules" produced by Gansu Fuzheng Pharmaceutical Technology Co., Ltd.;

[0289] Negative control group: given normal saline;

[0290] Comparative group: The Chinese patent document with application publication number "CN 115316623 A" mentioned in the background technology discloses a composition for constipation and a composition for constipation provided by a raw material powdering device;

[0291] The administration method can be oral gavage, which should be administered at noon every day for 7 consecutive days.

[0292] During the administration period, the defecation of mice was observed and recorded regularly every day, including the frequency of defecation and the shape of feces. The mice were weighed regularly to monitor their health status. The results are shown in Table 1 below.

[0293] Table 1 Observation results of mouse constipation treatment experiment

[0294]

[0295] It can be seen from Table 1 that the weight of the mice in the experimental group increased significantly after 7 days compared with the negative control group, the frequency of defecation increased slightly after administration, and the stool shape became significantly softer, the color deepened, the shape was closer to normal, and the moisture content increased; while the weight of the mice in the positive control group decreased, the stool was thin, and the moisture content increased significantly; although the control group also improved, it was less effective than the present invention. This may be because the defecation of the mice in the experimental group can help intestinal peristalsis to regulate intestinal function, so as to achieve the effect of smooth defecation and weight gain, significantly improve constipation symptoms and good safety, and is suitable for long-term consumption; the control group cannot fully exert the effect of its composition due to its processing method, and can only achieve a slightly improved effect, which does not reach the expected value; and the positive control group has too strong a drug to make the mouse feces thin, with signs of diarrhea, and the weight does not increase but decrease.

[0296] Experiment 2

[0297] After one week of drug administration in the same manner as in Experiment 1, 0.1 g of feces from the anus of the mice was collected aseptically, and a 10-fold serial dilution was performed, and the cells were inoculated on Bifidobacterium BBL agar and Lactobacillus LBS agar medium, respectively. After culturing for 24 hours, the colony numbers of Bifidobacterium and Lactobacillus were counted (rounding was used to obtain integers for statistical convenience). The results are shown in Table 2.

[0298] Table 2 Bacterial flora regulation effect

[0299] level Bifidobacterium count (CFU / g) Lactobacillus count (CFU / g) Experimental Group 1.5×10^8 2.0×10^8 Positive control group 0.9×10^7 0.9×10^8 Negative control group 1.1×10^8 1.3±10^8 Comparison group 1.0×10^8 1.4×10^8

[0300] It can be seen from Table 2 that the numbers of bifidobacteria and lactobacilli in the feces of the control group and the negative control group are similar, which proves that the control group has no effect on regulating the intestinal flora; the positive control group destroys the stability of the intestinal flora, and only the experimental group can significantly regulate the intestinal flora of mice.

Claims

1. A composition for constipation, comprising 130-140 parts of pumpkin powder, 30-35 parts of Poria powder, 40-50 parts of Tremella powder, 80-90 parts of aloe powder, and 80-90 parts of prebiotics, characterized in that: The preparation method of the composition for constipation is as follows: Step 1: Prepare pumpkin powder S11. Material selection and cleaning: select old pumpkins that are highly mature and not rotten or deteriorated, remove the pedicle and stem, clean and drain, soak in disinfectant, and then clean with drinking water 3-4 times; S12, slicing and blanching: cutting the washed pumpkin into slices, and then blanching; S13, vacuum freeze drying: vacuum freeze drying the blanched pumpkin slices; S14, ultrafine grinding: ultrafine grinding the vacuum freeze-dried pumpkin slices to a size of more than 200 meshes; S15, fermentation: inoculate the ultrafinely crushed pumpkin powder with a compound lactic acid bacteria starter, and ferment at 18-25° C. for 7-15 days until the pH value at the end of the fermentation is 3.0-3.5; S16, drying: drying at 40-60° C. to make the water content less than or equal to 5%, to obtain pumpkin powder; Step 2: Prepare Poria powder S21, raw material preparation: select dry, mildew-free Poria cocos and crush it into 20-60 mesh; S22, supercritical extraction: subjecting the crushed Poria cocos powder to supercritical extraction; S23, separation and concentration: after the supercritical extraction is completed, an extract containing the effective ingredients of Poria cocos is separated and concentrated to obtain a concentrated Poria cocos extract; S24, vacuum freeze drying: vacuum freeze drying the concentrated Poria cocos extract until the water content is less than or equal to 5%; S25, ultrafine grinding: ultrafine grinding the vacuum-dried Poria cocos to a size of more than 200 meshes to obtain Poria cocos powder; Step 3: Prepare Tremella Powder S31, raw material preparation: select dry, mildew-free Tremella fuciformis and crush it to more than 100 mesh; S32, suspension preparation: mixing the crushed Tremella fuciformis with water to form a suspension; S33, pH adjustment: add citric acid to the suspension to adjust the pH to 4-5; S34, enzymatic hydrolysis: at a temperature of 50-60° C., pectinase, acid cellulase, and neutral protease are sequentially added to the suspension for enzymatic hydrolysis; S35, filtering and drying: After the enzymatic hydrolysis is completed, the suspension is centrifuged, the liquid component is taken, concentrated, dried, and ultrafinely ground to more than 200 meshes to obtain Tremella powder; Step 4: Prepare aloe vera powder S41. Raw material preparation: select fresh aloe leaves free of pests and diseases, wash and remove impurities; S42, cutting and crushing: cutting the cleaned aloe leaves into blocks of appropriate size using an aloe crushing and blending machine, and then crushing and beating the blocks using an aloe crushing and blending machine until aloe pulp is formed, and collecting the aloe pulp; S43, enzymatic hydrolysis: adding pectinase, acid cellulase and neutral protease to the aloe pulp in sequence at a temperature of 40-50° C. for enzymatic hydrolysis; S44, centrifugation and filtration: after the enzymatic hydrolysis is completed, the aloe slurry is centrifuged to obtain the liquid component, filter, concentrate and dry; S45, ultrafine grinding: ultrafine grinding to more than 200 meshes to obtain aloe powder; Step 5: Prepare a composition for constipation 130-140 parts of pumpkin powder prepared in step 1 to step 5, 30-35 parts of Poria powder, 40-50 parts of Tremella powder, 80-90 parts of aloe powder and 80-90 parts of prebiotics are mixed evenly to prepare capsules to obtain a composition for constipation.

2. A composition for constipation according to claim 1, characterized in that: In the step 1, when preparing pumpkin powder: In step S12, the washed pumpkin is cut into slices of 5-8 cm x 5-8 cm x 2 cm; the blanching treatment is to blanch the pumpkin slices in 90° C. boiling water for 2-3 minutes; Step S13, the vacuum freeze drying process is as follows: Pre-freezing stage: Freeze at -20 to -30°C for 10-15 hours; Drying stage 1: Drying at a vacuum degree of 0.1-0.5mbar and a temperature of 40-50℃ for 8-10 hours; Drying stage 2: Drying for 5-8 hours at a vacuum degree of 0.1-0.5 mbar and a temperature of 20-30°C; In step S15, the inoculation amount of the composite lactic acid bacteria fermentation agent is 1-3% of the weight of the pumpkin powder, and the composite lactic acid bacteria fermentation agent is obtained by compounding Lactobacillus plantarum, Lactobacillus restiger and Lactobacillus brevis in a mass ratio of 2:1:

1.

3. A composition for constipation according to claim 1, characterized in that: In the step 2, when preparing the Poria powder: In step S22, the specific method of supercritical extraction is: placing the crushed Poria cocos powder in a supercritical extraction device, setting the extraction conditions to a temperature of 35-40° C., a pressure of 20-40 MPa, an extraction time of 2-4 h, and introducing carbon dioxide as an extractant for supercritical extraction; In step S24, the specific method of vacuum freeze drying is: after pre-freezing the concentrated Poria cocos extract at -40 to -60°C for 8-10 hours, sublimation drying is performed under the conditions of vacuum degree of 10-20Pa and temperature of 30-50°C to make the water content less than or equal to 5%.

4. A composition for constipation according to claim 1, characterized in that: In the step 3, when preparing Tremella powder: In step S32, the crushed Tremella fuciformis is mixed with water in a mass ratio of 1:5-10 to form a suspension; In step S34, during the enzymatic hydrolysis, pectinase is first added, and the amount of pectinase added is 0.08-0.12% of the mass of the Tremella fuciformis treated in step S31, and the reaction is carried out for 80-90 minutes; Then add acid cellulase, the amount of acid cellulase added is 0.08-0.12% of the mass of Tremella fuciformis after treatment in step S31, and react for 60-80 minutes; Finally, neutral protease is added, wherein the amount of the neutral protease added is 0.08-0.12% of the mass of the Tremella fuciformis after treatment in step S31, and the reaction is carried out for 40-60 minutes.

5. A composition for constipation according to claim 1, characterized in that: In the step 4, when preparing aloe vera powder: In step S42, the aloe vera crushing mixer comprises a protective frame (1) and a crushing structure installed inside the protective frame (1), one side of the protective frame (1) is connected to a feed barrel (2), one side of the feed barrel (2) is provided with a cutting structure, and the cutting structure is used to cut the aloe vera into segments, the crushing structure comprises a crushing protective shell (3), a first conveying screw rod (4) and two crushing rollers (5), the interior of the feed barrel (2) is connected to the interior of the crushing protective shell (3), the first conveying screw rod (4) and the two crushing rollers (5) are both located inside the crushing protective shell (3) and both ends are rotatably connected to the side wall of the crushing protective shell (3), a plurality of meshing teeth (6) are provided on the roller bodies of the two crushing rollers (5), the first conveying screw rod (4) is located below the two crushing rollers (5), and the first conveying screw rod (4) is fixedly connected to a first spiral conveying blade (9); The crushing structure is provided with a guide structure for guiding the movement of the aloe vera, and the bottom of the crushing structure is provided with a separation structure for separating the crushed aloe vera into dry and wet parts. One side of the separation structure is connected to an aloe vera stirring tank (7), and the separation structure is connected to the aloe vera stirring tank (7) via a liquid outlet pipe (8); The meshing teeth (6) on the roller bodies of the two pulverizing rollers (5) are staggered, the first conveying screw rod (4) is located at the center below the two pulverizing rollers (5), the outer side wall of the first spiral conveying blade (9) is slidably connected to the bottom of the inner cavity of the pulverizing protection shell (3), and the bottom of the pulverizing protection shell (3) is provided with a first discharge port (10), and the first discharge port (10) is located at the bottom of one side of the first conveying screw rod (4); The same end of the first conveying screw rod (4) and the two crushing rollers (5) penetrates the crushing protection shell (3) and extends outside; the roller bodies of the two crushing rollers (5) are respectively fixedly connected with a first driving gear (11) and a first driven gear (12); a first driving motor (13) is arranged on a side of the protection frame (1) close to the first driving gear (11); an output shaft of the first driving motor (13) penetrates the protection frame (1) and is fixedly connected to the crushing rollers (5) connected with the first driving gear (11); The first conveying screw rod (4) is connected to one of the crushing rollers (5) via a third transmission belt (14).

6. A composition for constipation according to claim 5, characterized in that: The cutting structure comprises a cutting disc (15) and a lifting plate (16); a slide groove (17) and a tool installation groove (18) are provided on the same side of the interior of the feed barrel (2); the lifting plate (16) is slidably connected in the slide groove (17) and the bottom thereof abuts against the upper surface of the crushing protection shell (3); the tool installation groove (18) is located above the slide groove (17); and the cutting disc (15) is rotatably connected in the tool installation groove (18); A first through hole (19) is provided at the bottom of the lifting plate (16), and transfer rods (20) are fixedly connected to both sides of the first through hole (19), and the two transfer rods (20) are rotatably connected to the same support plate (21), and a fixed shaft sleeve (22) is symmetrically fixedly connected to the upper surface of the crushing protection shell (3) on one side close to the feed barrel (2), and the opposite side surfaces of the two fixed shaft sleeves (22) are fixedly connected to pins (23), and the free end of the support plate (21) is rotatably connected to the two pins (23); A second drive motor (24) is provided at the bottom of one side of the crushing protection housing (3) close to the feed barrel (2), and an output shaft of the second drive motor (24) is fixedly connected to the bottom of the cutting disc (15); A top seat (25) is fixedly connected to one side of the lifting plate (16), and a roller (26) is rotatably connected to the bottom of the top seat (25); one end of one of the crushing rollers (5) close to the feed barrel (2) is fixedly connected to a main rotating rod (27), and one side of the crushing protection shell (3) is fixedly connected to a secondary rotating rod (28); the top seat (25), the main rotating rod (27) and the secondary rotating rod (28) are located on the same side, and the main rotating rod (27) and the secondary rotating rod (28) are connected in transmission via a fourth transmission belt (29); The auxiliary rotating rod (28) is fixedly connected with a convex top wheel (30), and the roller (26) is in rolling contact with the outer side surface of the convex top wheel (30); A baffle (31) is symmetrically arranged on the upper surface of one side of the crushing protection shell (3) close to the feed barrel (2), and the baffle (31) is located on both sides of the support plate (21).

7. A composition for constipation according to claim 6, characterized in that: The guide structure comprises a dustproof protective shell (73), the dustproof protective shell (73) is symmetrically mounted on both sides of the top of the crushing protective shell (3), and the two dustproof protective shells (73) are provided with a second through-hole (32) on opposite sides, the first rotating shaft (33) is rotatably connected to the inner sides of the crushing protective shell (3), the two first rotating shafts (33) are sleeved with the same first transmission belt (34), a plurality of belt sleeves (35) are fixedly connected to the outer side wall of the first transmission belt (34), the upper surfaces of the plurality of belt sleeves (35) are fixedly connected to an insert disk (36), the outer side surface of the insert disk (36) is rotatably connected to a pusher claw (37), and the pusher claw (37) is located in the second through-hole (32); The upper surface of the insert plate (36) is provided with a sliding groove (38) in a circumferential manner, and a sliding sleeve (39) adapted to the sliding groove (38) is embedded in the sliding groove (38), the interior of the sliding sleeve (39) is hollow and the top is open, and an ejector rod (40) and a first compression spring (41) are arranged inside the sliding sleeve (39), the first compression spring (41) is sleeved on the rod body of the ejector rod (40), and the two ends of the first compression spring (41) are respectively fixedly connected to the ejector rod (40) and one side of the interior of the sliding sleeve (39), and one end of the ejector rod (40) passes through the sliding sleeve (39) and extends outside; The upper surface of the pusher claw (37) is fixedly connected with a docking piece (42), and the other end of the docking piece (42) is fixedly connected to the upper surface of one side of the ejection rod (40).

8. A composition for constipation according to claim 7, characterized in that: An extension plate (43) is provided on one side of the crushing protection housing (3), and a steering gear (44) is rotatably connected to the upper surface of the extension plate (43), wherein the bottom of one of the first rotating shafts (33) passes through the dustproof protection housing (73) and extends outside, and a second driving gear (45) is fixedly connected to the shaft body of the extended first rotating shaft (33), and the steering gear (44) is meshed with the second driving gear (45); A rotating rod (46) is fixedly connected to the upper surface of the steering gear (44), a second transmission belt (47) is sleeved on the rod body of the rotating rod (46), and the rotating rod (46) is transmission-connected to a first rotating shaft (33) in a dustproof protective housing (73) away from the second driving gear (45) through the second transmission belt (47); The outer side walls of the two dust-proof protective shells (73) close to the feeding barrel (2) are both provided with avoidance grooves (48); The separation structure comprises a separation protection shell (49) and a second conveying screw rod (50), wherein the separation protection shell (49) is located below the crushing protection shell (3) and a discharge port (51) is provided on one side of the top of the separation protection shell (49), wherein the discharge port (51) is communicated with the first discharge port (10), the second conveying screw rod (50) is rotatably connected to the interior of the separation protection shell (49), a second spiral conveying blade (52) is fixedly connected to the second conveying screw rod (50), a filtering portion (53) is provided at the bottom of the separation protection shell (49), and an outer side wall of the second spiral conveying blade (52) is slidably connected to an inner wall of the filtering portion (53); A discharge housing (54) is fixedly sleeved on one side of the separation protection housing (49), the bottom of the discharge housing (54) is open, and the bottom of the protection frame (1) is provided with an opening connected to the discharge housing (54); A limiting rod (55) is fixedly connected to one side of the inner wall of the discharge housing (54), a sliding plate (56) is slidably connected to the limiting rod (55), a second pressure spring (57) is sleeved on the limiting rod (55), the second pressure spring (57) is located between the sliding plate (56) and the discharge housing (54), and two ends of the second pressure spring (57) are respectively fixedly connected to the sliding plate (56) and the discharge housing (54); One end of the second conveying screw rod (50) away from the feeding barrel (2) passes through the separation protection shell (49) and extends outside, and the second conveying screw rod (50) is connected to the first conveying screw rod (4) through a fifth transmission belt (58). The bottom of the separation protection shell (49) is fixedly connected to a collection frame (59), the bottom of the inner cavity of the collection frame (59) is provided with an inclined surface (60), one side of the collection frame (59) is connected to a liquid outlet pipe (8), the collection frame (59) is connected to the aloe stirring tank (7) through the liquid outlet pipe (8), and the top of the inner cavity of the aloe stirring tank (7) is provided with a stirring structure; The stirring structure comprises a first main driving gear (61) and an inner gear ring (62), wherein the inner gear ring (62) is fixedly connected to the top of the inner cavity of the aloe stirring tank (7), and the inner gear ring (62) is meshed with a plurality of sets of second driven gears (63), and the bottoms of the plurality of sets of the second driven gears (63) are all fixedly connected to a first stirring shaft (64), and the first stirring shaft (64) is fixedly connected to a plurality of sets of first stirring rods (65); A first main driving gear (61) is meshed between the plurality of second driven gears (63); a second stirring shaft (66) is fixedly connected to the bottom of the first main driving gear (61); a plurality of second stirring rods (67) are fixedly connected to the second stirring shaft (66); and the first stirring rod (65) and the second stirring rod (67) are staggered. The upper surfaces of the first main driving gear (61) and the plurality of groups of second driven gears (63) are rotatably connected to the top of the inner cavity of the aloe stirring tank (7); the top of the second stirring shaft (66) penetrates the first main driving gear (61) and the aloe stirring tank (7) and extends outside; a third driving motor (68) is arranged on the top of the aloe stirring tank (7); the output shaft of the third driving motor (68) is fixedly connected to the second stirring shaft (66); the upper surface of the aloe stirring tank (7) is rotatably connected to the second main driving gear (69) and the auxiliary transmission gear (70); the second main driving gear (69) and the auxiliary transmission gear (70) are meshed with each other, and the second main driving gear (69) is sleeved on the second stirring shaft (66); the upper surface of the auxiliary transmission gear (70) is fixedly connected to the docking shaft (71), and the bottom of the first rotating shaft (33) of the second driving gear (45) is fixedly connected to the top of the docking shaft (71); One side of the bottom of the aloe stirring tank (7) is connected to a drain pipe (72).

9. A composition for constipation according to claim 1, characterized in that: In the step 4, when preparing aloe vera powder: In step S43, during the enzymatic hydrolysis, pectinase is first added, and the amount of pectinase added is 0.08-0.12% of the mass of the aloe leaves after the treatment in step S41, and the reaction is carried out for 100-120 minutes; Then, add acid cellulase, wherein the amount of the acid cellulase added is 0.08-0.12% of the mass of the aloe leaves after treatment in step S41, and react for 70-90 minutes; Finally, neutral protease is added, and the amount of the neutral protease added is also 0.08-0.12% of the mass of the aloe leaves after treatment in step 431, and the reaction is carried out for 50-70 minutes.

10. Use of a composition for constipation according to any one of claims 1 to 9, characterized in that: Used to relieve symptoms of constipation.

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