Closed reaction kettle for producing aprepitant

Abstract

The utility model discloses a closed reaction kettle for producing aprepitant. The closed reaction kettle comprises a kettle body, the feeding hole is formed in the kettle body; the discharge hole is formed in the kettle body; the base is arranged on the kettle body; the mounting block is arranged on the base opposite to the other side of the kettle body; the speed reducer is arranged on the mounting block opposite to the other side of the base; the motor is arranged on the speed reducer opposite to the other side of the mounting block; and the stirring mechanism is connected with the speed reducer and the kettle body. According to the closed reaction kettle for aprepitant production disclosed by the utility model, the stirring block can be replaced, the operation is simple, and the storage of more other stirring parts is avoided.

Description

Technical Field

[0001] The utility model relates to the technical field of reactors, in particular to a closed reactor for producing aprepitant. Background Art

[0002] Reactors are containers used for chemical reactions, often in industrial production. They can carry out various chemical reactions under controlled conditions, such as synthetic chemical reactions, dissolution, acid-base neutralization, etc. Reactors are usually made of high temperature and corrosion resistant materials to ensure safety and reaction efficiency. In industrial production, reactors usually have a stirring function to ensure that the reactants are evenly mixed, and the reaction conditions such as temperature and pressure can be controlled. The design of the reactor can be adjusted according to the specific reaction requirements to meet different production requirements.

[0003] During the experiment and production process of aprepitant, process adjustments often occur. When adjusting the stirring parameters, the stirring wheel of the reactor on the market cannot be directly replaced. It can only be achieved by replacing multiple stirring parts, which is cumbersome to operate and requires the storage of a large number of stirring parts other than the stirring wheel. Utility Model Content

[0004] The utility model aims at the deficiencies existing in the prior art and provides a closed reaction kettle for producing aprepitant with replaceable stirring wheels, which is easy to operate.

[0005] The purpose of the utility model is achieved in the following manner: a closed reactor for producing aprepitant, comprising:

[0006] Kettle body;

[0007] A feed inlet is provided on the kettle body;

[0008] A discharge port is provided on the kettle body;

[0009] A base, arranged on the kettle body;

[0010] A mounting block is disposed on the base at the other side of the kettle body;

[0011] A reducer is arranged on the mounting block on the other side of the base;

[0012] A motor, arranged on the reducer on the other side relative to the mounting block;

[0013] A stirring mechanism, connected to the reducer and to the kettle body;

[0014] The stirring mechanism includes: a stirring shaft connected to the reducer; a stirring block connected to the stirring shaft; a hole is provided in the stirring shaft; an adjusting rod is provided inside the stirring shaft and connected to the hole; the hole is provided with a first limit hole; a first limit block is provided at one end of the adjusting rod, and the first limit block is connected to the first limit hole; an adjusting block is provided on the adjusting rod; a sliding hole is provided in the stirring shaft; the sliding hole is communicated with the hole; a fixed hole is provided in the stirring block; a movable block is connected to the sliding hole and the fixed hole; a second limit block is provided on the movable block; the movable block is provided with a groove; the groove is connected to the adjusting block; a first spring is provided in the sliding hole, connected to the movable block, and connected to the second limit block; a limiting mechanism is connected to the adjusting rod.

[0015] As an optional solution of the technical solution of the utility model, the limiting mechanism includes:

[0016] A limiting block is arranged on the adjusting rod;

[0017] a limiting hole, communicating with the hole and connected with the limiting block;

[0018] A first telescopic hole is provided on the limiting block;

[0019] A second telescopic hole is provided on the stirring shaft;

[0020] a telescopic rod connected to the first telescopic hole and connected to the second telescopic hole;

[0021] A third limit block is provided on the telescopic rod;

[0022] The second spring is arranged in the first telescopic hole, connected to the telescopic rod, and connected to the third limiting block.

[0023] As an optional solution of the technical solution of the utility model, the stirring mechanism also includes:

[0024] A first fixing frame, disposed in the mounting block and connected to the stirring shaft;

[0025] The second fixing frame is arranged inside the kettle body and connected with the stirring shaft.

[0026] As an optional solution of the technical solution of the utility model, the limiting mechanism also includes:

[0027] The rotating hole is arranged in the stirring shaft and communicated with the limiting hole.

[0028] The beneficial effects of the utility model are:

[0029] The utility model discloses a closed reaction kettle for producing aprepitant, which is provided with a stirring mechanism and a limiting mechanism. The limiting mechanism limits the stirring mechanism. When the telescopic rod is extended out of the stirring shaft, the adjusting rod cannot rotate; when the telescopic rod is retracted into the stirring shaft, the adjusting rod can rotate, and the adjusting rod drives the adjusting block to rotate, thereby changing the position of the movable block, thereby adjusting the movement of the stirring block. When the stirring block is not in the stirring block, the stirring can be movable, thereby realizing the replacement of the stirring block. The operation is simple, and it is avoided to store a large number of other stirring components. BRIEF DESCRIPTION OF THE DRAWINGS

[0030] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0031] Figure 1 This is a schematic diagram of a closed reactor for producing aprepitant according to Example 1 of the utility model;

[0032] Figure 2 This is a schematic diagram of a stirring mechanism of a closed reactor for producing aprepitant according to Example 1 of the utility model;

[0033] Figure 3 A bottom view of a stirring mechanism of a closed reaction kettle for producing aprepitant according to Example 1 of the utility model;

[0034] Figure 4 This is an enlarged structural view of location A of a closed reactor for producing aprepitant in Example 1 of the utility model;

[0035] Figure 5 This is an enlarged structural view of location B of a closed reactor for producing aprepitant in Example 1 of the utility model;

[0036] Figure 6 This is an enlarged view of the structure at position C of a closed reactor for producing aprepitant in Example 1 of the utility model.

[0037] Reference numerals:

[0038] 1- kettle body;

[0039] 2-feeding port;

[0040] 3- Base;

[0041] 4-Mounting block;

[0042] 5- reducer;

[0043] 6- Motor;

[0044] 7-stirring mechanism; 701-stirring shaft; 702-stirring block; 703-adjusting rod; 704-hole; 705-first limiting block; 706-first limiting hole; 707-adjusting block; 708-movable block; 709-groove; 710-fixing hole; 711-first spring; 712-limiting block; 713-telescopic rod; 714-third limiting block; 715-first telescopic hole; 716-second spring; 717-second fixing frame; 718-first fixing frame; 719-sliding hole; 720-rotating hole; 721-limiting hole; 722-second limiting block; 723-second telescopic hole;

[0045] 8-Discharge port. DETAILED DESCRIPTION

[0046] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments.

[0047] It should be noted that all directional indications in the embodiments of the present invention (such as up, down, left, right, front, back...) are only used to explain the relative position relationship, movement status, etc. between the components under a certain specific posture (as shown in the accompanying drawings). If the specific posture changes, the directional indication will also change accordingly.

[0048] In the description of the embodiments, unless otherwise clearly specified and limited, the terms "disposed", "connected" and the like should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection, a direct connection, a connection through an intermediate medium, or a communication between two components. For ordinary technicians in this field, the specific meanings of the above terms in the present utility model can be understood according to specific circumstances.

[0049] Example 1

[0050] like Figure 1-6 As shown, a closed reaction kettle for producing aprepitant comprises: a kettle body 1, a feed port 2, a discharge port 8, a base 3, a mounting block 4, a reducer 5, a motor 6, and a stirring mechanism 7, wherein: the feed port 2 is arranged on the kettle body 1; the discharge port 8 is arranged on the kettle body 1; the base 3 is arranged on the kettle body 1; the mounting block 4 is arranged on the base 3 on the other side of the kettle body 1; the reducer 5 is arranged on the mounting block 4 on the other side of the base 3; the motor 6 is arranged on the reducer 5 on the other side of the mounting block 4; the stirring mechanism 7 is connected to the reducer 5 and connected to the kettle body 1. The motor 6 drives the stirring mechanism 7 to rotate through the reducer 5.

[0051] Specifically, the stirring mechanism 7 includes: a stirring shaft 701, a stirring block 702, a hole 704, an adjusting rod 703, a first limiting hole 706, a first limiting block 705, an adjusting block 707, a sliding hole 719, a fixing hole 710, a movable block 708, a second limiting block 722, a groove 709, a first spring 711, and a limiting mechanism, wherein: the stirring shaft 701 is connected to the reducer 5; the stirring block 702 is connected to the stirring shaft 701; a hole 704 is provided in the stirring shaft 701; the adjusting rod 703 is provided inside the stirring shaft 701 and connected to the hole 704; the hole 704 is provided with a first limiting hole 706; one end of the adjusting rod 703 is provided with a first A limit block 705, a first limit block 705 is connected to a first limit hole 706; an adjustment block 707 is provided on the adjustment rod 703; a sliding hole 719 is provided in the stirring shaft 701; the sliding hole 719 is communicated with the hole 704; a fixing hole 710 is provided in the stirring block 702; a movable block 708 is connected to the sliding hole 719, and is connected to the fixing hole 710; a second limit block 722 is provided on the movable block 708; the movable block 708 is provided with a groove 709; the groove 709 is connected to the adjustment block 707; a first spring 711 is provided in the sliding hole 719, is connected to the movable block 708, and is connected to the second limit block 722; the limiting mechanism is connected to the adjustment rod 703.

[0052] Specifically, the limiting mechanism includes: a limiting block 712, a limiting hole 721, a first telescopic hole 715, a second telescopic hole 723, a telescopic rod 713, a third limit block 714, and a second spring 716, wherein: the limiting block 712 is arranged on the adjusting rod 703; the limiting hole 721 is connected to the hole 704 and is connected to the limiting block 712; the first telescopic hole 715 is arranged on the limiting block 712; the second telescopic hole 723 is arranged on the stirring shaft 701; the telescopic rod 713 is connected to the first telescopic hole 715 and to the second telescopic hole 723; the third limit block 714 is arranged on the telescopic rod 713; the second spring 716 is arranged in the first telescopic hole 715, connected to the telescopic rod 713, and connected to the third limit block 714.

[0053] like Figure 1 As shown, as a further solution of this embodiment, the stirring mechanism 7 also includes: a first fixed frame 718 and a second fixed frame 717, wherein: the first fixed frame 718 is arranged in the mounting block 4 and connected to the stirring shaft 701; the second fixed frame 717 is arranged on the inside of the kettle body 1 and connected to the stirring shaft 701.

[0054] like Figure 5 As shown, as a further solution of this embodiment, the limiting mechanism further includes: a rotating hole 720 , which is disposed in the stirring shaft 701 and communicated with the limiting hole 721 .

[0055] like Figure 2-6As shown, in the initial state, one end of the telescopic rod 713 extends out of the stirring shaft 701 through the second telescopic hole 723, and the telescopic rod 713 blocks the adjustment rod 703 from rotating relative to the stirring shaft 701, thereby limiting the adjustment rod 703; at this time, the adjustment block 707 squeezes the movable block 708, and the second limit block 722 squeezes the first spring 711, and the first spring 711 is in a compressed state; at this time, the movable block 708 has a fixing effect on the mixing block 702.

[0056] The telescopic rod 713 is pressed, so that one end of the telescopic rod 713 extending out of the stirring shaft 701 passes through the second telescopic hole 723 and enters the interior of the stirring shaft 701. At this time, the third limit block 714 squeezes the second spring 716, and the second spring 716 enters a compressed state; when the telescopic rod 713 completely enters the limiting block 712, the telescopic rod 713 releases the restriction on the adjusting rod 703, and the adjusting rod 703 can rotate relative to the stirring shaft 701; Figure 3 From the perspective shown, the adjusting rod 703 is rotated clockwise, and the adjusting rod 703 drives the adjusting block 707 to rotate. During the rotation, one end of the telescopic rod 713 slides in the rotating hole 720, and the squeezing strength of the adjusting block 707 on the movable block 708 gradually decreases. The first spring 711 drives the movable block 708 to move toward the inside of the stirring shaft 701 through the second limit block 722; when the adjusting rod 703 is rotated 90° clockwise, the squeezing strength of the adjusting block 707 on the movable block 708 is minimal, and the first spring 711 drives the movable block 708 to completely break away from the stirring block 702 and enter the inside of the stirring shaft 701; at this time, the stirring block 702 is not fixed by the movable block 708 and can fall off the stirring shaft 701.

[0057] When the adjusting rod 703 is rotated 90° counterclockwise, the stirring mechanism 7 returns to its initial state, and the second spring 716 drives one end of the telescopic rod 713 to extend out of the stirring shaft 701 through the third limiting block 714, limiting the rotation of the adjusting rod 703 relative to the stirring shaft 701, and the adjusting block 707 exerts the maximum squeezing strength on the movable block 708, and the movable block 708 completely enters the fixing hole 710, completing the fixation of the stirring block 702.

[0058] The working process of this embodiment is as follows: when disassembling the old stirring block 702, first, press the telescopic rod 713 so that the telescopic rod 713 completely enters the limiting block 712, and keep pressing the telescopic rod 713 before rotating; then, rotate the telescopic rod 713 90° clockwise so that the stirring block 702 is not fixed by the movable block 708; then, remove the old stirring block 702 from the stirring shaft 701; when installing the new stirring block 702, first, place the new stirring block 702 in the position of the old stirring block 702; then, rotate the adjusting rod 703 counterclockwise 90° so that one end of the telescopic rod 713 extends out of the stirring shaft 701, limiting the rotation of the adjusting rod 703 relative to the stirring shaft 701, and the movable block 708 completely enters the fixing hole 710, thereby completing the fixation of the stirring block 702.

[0059] The above is only a preferred embodiment of the utility model, and is not intended to limit the utility model. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the utility model shall be included in the protection scope of the utility model. In addition, the technical solutions between the various embodiments can be combined with each other, but it must be based on the ability of ordinary technicians in the field to implement; when the combination of technical solutions is contradictory or cannot be implemented, it should be considered that such a combination of technical solutions does not exist and is not within the protection scope required by the utility model.

Claims

1. A closed reactor for producing aprepitant, characterized in that: include: Kettle body (1); A feed inlet (2) is provided on the kettle body (1); A discharge port (8) is provided on the kettle body (1); A base (3) is arranged on the kettle body (1); A mounting block (4) is arranged on the base (3) at the other side of the kettle body (1); A reducer (5) is arranged on the mounting block (4) on the other side relative to the base (3); A motor (6) is arranged on the reducer (5) on the other side relative to the mounting block (4); A stirring mechanism (7) connected to the reducer (5) and to the kettle body (1); The stirring mechanism (7) comprises: a stirring shaft (701) connected to the reducer (5); a stirring block (702) connected to the stirring shaft (701); a hole (704) is provided in the stirring shaft (701); an adjusting rod (703) is provided inside the stirring shaft (701) and connected to the hole (704); the hole (704) is provided with a first limiting hole (706); a first limiting block (705) is provided at one end of the adjusting rod (703), and the first limiting block (705) is connected to the first limiting hole (706); an adjusting block (707) is provided on the adjusting rod (703); a sliding hole (707) is provided in the stirring shaft (701); 19); the sliding hole (719) is connected to the hole (704); a fixing hole (710) is provided in the stirring block (702); a movable block (708) is connected to the sliding hole (719) and the fixing hole (710); a second limit block (722) is provided on the movable block (708); the movable block (708) is provided with a groove (709); the groove (709) is connected to the adjusting block (707); a first spring (711) is provided in the sliding hole (719), connected to the movable block (708), and connected to the second limit block (722); a limiting mechanism is connected to the adjusting rod (703).

2. The closed reactor for producing aprepitant according to claim 1, characterized in that: The limiting mechanisms include: A limiting block (712) is arranged on the adjusting rod (703); A limiting hole (721) communicates with the hole (704) and is connected to the limiting block (712); A first telescopic hole (715) is provided on the limiting block (712); A second telescopic hole (723) is provided on the stirring shaft (701); A telescopic rod (713), connected to the first telescopic hole (715) and connected to the second telescopic hole (723); A third limiting block (714) is provided on the telescopic rod (713); The second spring (716) is arranged in the first telescopic hole (715), connected to the telescopic rod (713), and connected to the third limiting block (714).

3. The closed reactor for producing aprepitant according to claim 1, characterized in that: The stirring mechanism (7) further comprises: A first fixing frame (718) is disposed in the mounting block (4) and connected to the stirring shaft (701); The second fixing frame (717) is arranged inside the kettle body (1) and is connected to the stirring shaft (701).

4. The closed reactor for producing aprepitant according to claim 2, characterized in that: The limiting mechanism also includes: The rotating hole (720) is disposed in the stirring shaft (701) and is communicated with the limiting hole (721).

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