Detachable stirrer mechanism of bioreactor

Abstract

The utility model provides a detachable stirrer mechanism of a bioreactor, which relates to the technical field of biological reaction equipment and comprises a bioreactor body, a tank cover is arranged above the bioreactor body, a mounting assembly capable of fixing a stirrer is arranged below the tank cover, and the mounting assembly comprises a mounting frame. According to the detachable stirrer mechanism of the bioreactor, by arranging the mounting assembly and other parts, when a stirring mechanism is not needed in a biological reaction, a hydraulic telescopic rod pulls a pressing plate and a positioning rod to ascend, so that the positioning rod is separated from the interior of a positioning hole, and the fixing and limiting effects of the device on a mounting plate are relieved; then the mounting plate can be taken out from the interior of the mounting frame by pulling a handle, so that the stirring mechanism can be detached from the lower part of the tank cover, the detachable effect of the stirring mechanism is realized, a worker can conveniently clean and maintain the stirring mechanism, and the influence of the stirring mechanism on the reaction of the biological materials is avoided.

Description

Technical Field

[0001] The utility model relates to a stirrer mechanism, in particular to a detachable stirrer mechanism of a bioreactor, belonging to the technical field of bioreactor equipment. Background Art

[0002] A bioreactor is a device system that uses the biological functions of enzymes or organisms (such as microorganisms) to carry out biochemical reactions in vitro. It is a biological function simulator, such as a fermentation tank, immobilized enzyme or immobilized cell reactor.

[0003] A bioreactor with a stirring structure disclosed in the Chinese patent application CN217677458U comprises a bioreactor body, the bioreactor body comprises a tank cover arranged at the top, a motor is fixedly mounted on the upper surface of the tank cover, the output shaft of the motor penetrates the tank cover and is fixedly connected to a stirring shaft, a mounting groove is provided on the outer side of the stirring shaft, an electric telescopic rod is fixedly mounted on the upper surface of the inner cavity of the mounting groove, a connecting block is fixedly connected to the output end of the electric telescopic rod, a sleeve is fixedly mounted on one side of the connecting block, a plurality of stirring paddles are evenly fixedly mounted on the outer side of the sleeve, and a through hole is provided on the outer side of each stirring paddle. The sleeve in the utility model is arranged on the outer side of the stirring shaft, and by adjusting the electric telescopic rod, the connecting block connected to the output end thereof drives the sleeve to rise and fall, thereby controlling the stirring paddle to move up and down, solving the problem that the swing amplitude of the stirring member is limited, resulting in poor stirring effect and affecting the reaction efficiency.

[0004] According to the different characteristics of the reaction materials, the bioreactor does not need to use a stirring mechanism in some usage scenarios. However, the stirring mechanism in the above patent is fixed to the tank cover. When the stirring mechanism is not in use, it will occupy the space inside the bioreactor and will come into contact with the biological material, thereby affecting the reaction of the biological material. It is inconvenient for the staff to clean and maintain the stirring mechanism. In addition, the stirring paddles of the bioreactor for different cultured cells are also different, such as: lifting stirring paddles, inclined blade stirring paddles, spiral stirring paddles, etc. It is difficult to replace the stirring paddles according to the different reaction materials in the above device, and the applicability is low. Utility Model Content

[0005] 1. Technical issues to be resolved

[0006] The utility model provides a detachable agitator mechanism of a bioreactor to solve the problems in the prior art that the agitator mechanism in the reactor cannot be quickly disassembled and assembled, and the agitator blade is difficult to replace according to different reactants.

[0007] (II) Technical solution

[0008] The utility model is implemented through the following technical scheme: a detachable agitator mechanism of a bioreactor, comprising a bioreactor body, a tank cover is arranged above the bioreactor body, a mounting assembly capable of fixing the agitator is arranged below the tank cover, the mounting assembly comprises a mounting frame, the mounting frame is fixed to the bottom surface of the tank cover, a sliding slot is provided inside the mounting frame, a stirring mechanism capable of stirring biological materials is provided inside the bioreactor body, the stirring mechanism comprises a mounting plate, the outer surface of the mounting plate is slidably connected to the sliding slot, the interior of the mounting plate is provided with positioning holes distributed at equal distances, a driving motor is fixed to the bottom surface of the mounting plate, a clamping rod is fixed to the output end of the driving motor, a fixing sleeve is fixed to the outer surface of the clamping rod, and a spring is sleeved on the outer surface of the clamping rod.

[0009] Preferably, a hydraulic telescopic rod is fixed to the inner top wall of the mounting frame, and a pressure plate is fixed to the extended end of the hydraulic telescopic rod. The hydraulic telescopic rod can control the lifting and lowering of the pressure plate, and the pressure plate can squeeze and fix the mounting plate after it is lowered.

[0010] Preferably, positioning rods distributed at equal distances are fixed to the bottom surface of the pressure plate, and each of the positioning rods is plugged into a corresponding positioning hole. When the three side surfaces of the mounting plate are in contact with the inner wall of the sliding slot, the positions of the positioning rods and the positioning holes correspond. After being lowered, the positioning rods will be engaged in the positioning holes. At this time, the stirring shaft is in the center position of the bioreactor body, and the stability of the mounting plate is enhanced.

[0011] Preferably, a limiting slide is sleeved inside the fixed sleeve, and the limiting slide is slidably connected to the clamping rod. The limiting slide can slide along the outer surface of the clamping rod inside the limiting slide, and after the limiting slide slides upward, the bottom end of the clamping rod can be exposed.

[0012] Preferably, a handle is fixed to the bottom surface of the mounting plate, and the handle is fixed to the outer surface of the drive motor. A stirring shaft is provided under the mounting plate. When disassembling the stirring mechanism, the mounting plate is removed from the inside of the mounting frame by pulling the handle, which is convenient for the staff to operate.

[0013] Preferably, a stirring blade is fixed to the bottom end of the stirring shaft, and a T-shaped block is fixed to the upper end of the stirring shaft. A stirring shaft with corresponding stirring blades is selected according to the type of biological reaction materials.

[0014] Preferably, a T-shaped slot is provided inside the coupling rod, and the T-shaped slot and the T-shaped block are coupled to each other. After the T-shaped block and the T-shaped slot are coupled, a round rod is formed between the contact end of the coupling rod and the stirring shaft, and when the limiting slide is sleeved on the outer surface of the round rod, the upper end of the stirring shaft can be limited, thereby fixing the coupling rod and the stirring shaft together.

[0015] The utility model provides a detachable agitator mechanism for a bioreactor, which has the following beneficial effects:

[0016] 1. The detachable agitator mechanism of the bioreactor is provided with mounting components and the like. When the biological reaction does not need the agitator mechanism, the pressure plate and the positioning rod are pulled up by the hydraulic telescopic rod, so that the positioning rod is disengaged from the positioning hole, and the fixed limiting effect of the device on the mounting plate can be released. Then, the mounting plate can be taken out from the mounting frame by pulling the handle, so that the agitator mechanism can be removed from under the tank cover, thereby realizing the detachable effect of the agitator mechanism, facilitating the staff to clean and maintain the agitator mechanism, and avoiding the influence of the agitator mechanism on the reaction of the biological material.

[0017] 2. The detachable agitator mechanism of the bioreactor is provided with a stirring mechanism. According to different biological materials, when the device needs to replace the stirring shaft with the corresponding stirring blades, the limiting slide is pushed to slide upward to expose the bottom end of the clamping rod, and the T-shaped clamp is slid out of the T-shaped slot to remove the stirring shaft. Then, the corresponding T-shaped clamp at the upper end of the stirring shaft is clamped into the T-shaped slot, and the limiting slide is pushed back to its original position by the spring. The limiting slide can limit the movement of the stirring shaft, so that the clamping rod and the stirring shaft are fixed together, thereby achieving the purpose of quickly replacing the stirring shaft, and the applicability is stronger. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 This is a schematic diagram of the internal structure of the bioreactor body of the utility model;

[0019] Figure 2 This is a schematic diagram of the separate structure of the mounting frame and the mounting plate of the utility model;

[0020] Figure 3 It is a structural schematic diagram of the stirring shaft of the utility model;

[0021] Figure 4 This is an internal cross-sectional view of the fixing sleeve of the utility model.

[0022] Description of Reference Numerals

[0023] 1. Bioreactor body; 2. Tank cover;

[0024] 3. Installation assembly; 301. Installation frame; 302. Sliding slot; 303. Hydraulic telescopic rod; 304. Pressing plate; 305. Positioning rod;

[0025] 4. Stirring mechanism; 401. Mounting plate; 402. Positioning hole; 403. Driving motor; 404. Connecting rod; 405. Fixed sleeve; 406. Limiting slide; 407. Handle; 408. Stirring shaft; 409. Stirring blade; 410. T-shaped block; 411. T-shaped slot; 412. Spring. DETAILED DESCRIPTION

[0026] The embodiment of the utility model provides a detachable agitator mechanism of a bioreactor.

[0027] Please refer to Figure 1 , Figure 2 , Figure 3 and Figure 4 , including a bioreactor body 1, a tank cover 2 is arranged above the bioreactor body 1, and a mounting assembly 3 capable of fixing the agitator is arranged below the tank cover 2, the mounting assembly 3 includes a mounting frame 301, the mounting frame 301 is fixed to the bottom surface of the tank cover 2, a sliding slot 302 is opened inside the mounting frame 301, and a stirring mechanism 4 capable of stirring biological materials is arranged inside the bioreactor body 1, the stirring mechanism 4 includes a mounting plate 401, and the outer surface of the mounting plate 401 is slidably connected to the sliding slot 302, and the purpose of disassembling and assembling the stirring mechanism 4 inside the bioreactor body 1 is achieved by disassembling and installing the mounting plate 401 in the mounting frame 301.

[0028] A driving motor 403 is fixed to the bottom surface of the mounting plate 401 , and a clamping rod 404 is fixed to the output end of the driving motor 403 . The driving motor 403 provides power for the clamping rod 404 to rotate.

[0029] A fixed sleeve 405 is fixed to the outer surface of the clamping rod 404, and a spring 412 is sleeved on the outer surface of the clamping rod 404. A limiting slide 406 is sleeved inside the fixed sleeve 405, and the limiting slide 406 is slidably connected to the clamping rod 404. The limiting slide 406 can slide along the outer surface of the clamping rod 404 inside the limiting slide 406. After the limiting slide 406 slides upward, the bottom end of the clamping rod 404 can be exposed, and the spring 412 is installed inside the fixed sleeve 405. The limiting slide 406 will compress the spring 412 when moving upward. In the absence of interference from external force, the spring 412 can limit the movement of the limiting slide 406, thereby preventing the position of the limiting slide 406 from shifting when the stirring mechanism 4 is working or moving, causing the stirring shaft 408 to fall off.

[0030] Please refer to Figure 1 and Figure 2A hydraulic telescopic rod 303 is fixed to the inner top wall of the mounting frame 301, and a pressing plate 304 is fixed to the extended end of the hydraulic telescopic rod 303. The hydraulic telescopic rod 303 can control the lifting and lowering of the pressing plate 304. After the pressing plate 304 is lowered, it can squeeze and fix the mounting plate 401.

[0031] Please refer to Figure 1 and Figure 2 The interior of the mounting plate 401 is provided with equidistantly distributed positioning holes 402, and the bottom surface of the pressing plate 304 is fixed with equidistantly distributed positioning rods 305, each positioning rod 305 is plugged into the corresponding positioning hole 402, and when the three side surfaces of the mounting plate 401 are in contact with the inner wall of the sliding slot 302, the positions of the positioning rods 305 and the positioning holes 402 correspond, and the positioning rods 305 will be snapped into the positioning holes 402 after being lowered, and at this time, the stirring shaft 408 is at the center position of the bioreactor body 1, and the stability of the mounting plate 401 is enhanced.

[0032] Please refer to Figure 1 and Figure 2 A handle 407 is fixed to the bottom surface of the mounting plate 401, and the handle 407 is fixed to the outer surface of the driving motor 403. A stirring shaft 408 is provided under the mounting plate 401. When disassembling the stirring mechanism 4, the mounting plate 401 can be removed from the inside of the mounting frame 301 by pulling the handle 407, which is convenient for the staff to operate.

[0033] Please refer to Figure 1 and Figure 3 A stirring blade 409 is fixed to the bottom end of the stirring shaft 408, and a T-shaped block 410 is fixed to the upper end of the stirring shaft 408. The stirring shaft 408 with the corresponding stirring blade 409 is selected according to the type of biological reaction materials.

[0034] Please refer to Figure 3 and Figure 4 A T-shaped slot 411 is provided inside the clamping rod 404, and the T-shaped slot 411 is clamped with the T-shaped block 410. After the T-shaped block 410 and the T-shaped slot 411 are clamped, the contact end of the clamping rod 404 and the stirring shaft 408 will form a round rod. When the limiting slide cylinder 406 is sleeved on the outer surface of the round rod, the upper end of the stirring shaft 408 can be limited, so that the clamping rod 404 and the stirring shaft 408 are fixed together.

[0035] When the utility model is in use: when the stirring mechanism 4 is needed, the mounting plate 401 at the upper end of the stirring mechanism 4 is slid into the sliding slot 302 of the mounting frame 301, and then the pressure plate 304 and the positioning rod 305 are lowered by extending the hydraulic telescopic rod 303. When the positioning rod 305 is engaged in the positioning hole 402, the positioning rod 305 can limit the lateral movement of the mounting plate 401, and the pressure plate 304 will apply a downward squeezing force to the mounting plate 401, thereby achieving a fixing effect on the mounting plate 401. The stirring mechanism 4 can be fixed under the tank cover 2. Similarly, the hydraulic telescopic rod 303 pulls the pressing plate 304 and the positioning rod 305 up to release the fixing effect on the mounting plate 401. Then, the mounting plate 401 can be taken out from the inside of the mounting frame 301 by pulling the handle 407, so that the stirring mechanism 4 can be removed from under the tank cover 2, thereby realizing the detachable effect of the device, making it convenient for the staff to clean and maintain the stirring mechanism 4, and avoiding the stirring mechanism 4 from affecting the reaction of the biological material.

[0036] According to the different biological materials, when the device needs to replace the stirring shaft 408 with the corresponding stirring blade 409, the limiting slide 406 is pushed to slide upward so that the bottom end of the clamping rod 404 is exposed, and the T-shaped block 410 is slid out of the T-shaped slot 411 to remove the stirring shaft 408. Similarly, after the T-shaped block 410 at the upper end of the corresponding stirring shaft 408 is clamped into the T-shaped slot 411, the spring 412 pushes the limiting slide 406 back to its original position, and the limiting slide 406 limits the movement of the stirring shaft 408, so that the clamping rod 404 and the stirring shaft 408 are fixed together, thereby achieving the purpose of quickly replacing the stirring shaft 408.

[0037] The above shows and describes the basic principle and main features of the utility model and the advantages of the utility model. Those skilled in the art should understand that the utility model is not limited by the above embodiments. The above embodiments and descriptions are only for explaining the principle of the utility model. Without departing from the spirit and scope of the utility model, the utility model may have various changes and improvements, which fall within the scope of the utility model to be protected. The scope of protection claimed by the utility model is defined by the attached claims and their equivalents.

Claims

1. A detachable agitator mechanism for a bioreactor, comprising a bioreactor body (1), characterized in that: A tank cover (2) is arranged above the bioreactor body (1), and a mounting assembly (3) capable of fixing a stirrer is arranged below the tank cover (2), the mounting assembly (3) comprising a mounting frame (301), the mounting frame (301) being fixed to the bottom surface of the tank cover (2), a sliding slot (302) being arranged inside the mounting frame (301), and a stirring mechanism (4) capable of stirring biological materials is arranged inside the bioreactor body (1); The stirring mechanism (4) comprises a mounting plate (401), the outer surface of the mounting plate (401) is slidably connected to the sliding slot (302), the interior of the mounting plate (401) is provided with positioning holes (402) distributed at equal distances, a driving motor (403) is fixed to the bottom surface of the mounting plate (401), a clamping rod (404) is fixed to the output end of the driving motor (403), a fixing sleeve (405) is fixed to the outer surface of the clamping rod (404), and a spring (412) is sleeved on the outer surface of the clamping rod (404).

2. The detachable agitator mechanism of a bioreactor according to claim 1, characterized in that: A hydraulic telescopic rod (303) is fixed to the inner top wall of the mounting frame (301), and a pressing plate (304) is fixed to the extended end of the hydraulic telescopic rod (303).

3. A detachable agitator mechanism for a bioreactor according to claim 2, characterized in that: The bottom surface of the pressing plate (304) is fixed with positioning rods (305) distributed at equal distances, and each positioning rod (305) is plugged into a corresponding positioning hole (402).

4. The detachable agitator mechanism of a bioreactor according to claim 1, characterized in that: The interior of the fixed sleeve (405) is sleeved with a limiting slide cylinder (406), and the limiting slide cylinder (406) is slidably connected to the clamping rod (404).

5. The detachable agitator mechanism of a bioreactor according to claim 1, characterized in that: A handle (407) is fixed to the bottom surface of the mounting plate (401), and the handle (407) is fixed to the outer surface of the driving motor (403). A stirring shaft (408) is provided below the mounting plate (401).

6. A detachable agitator mechanism for a bioreactor according to claim 5, characterized in that: A stirring blade (409) is fixed to the bottom end of the stirring shaft (408), and a T-shaped block (410) is fixed to the upper end of the stirring shaft (408).

7. A detachable agitator mechanism for a bioreactor according to claim 6, characterized in that: A T-shaped slot (411) is provided inside the clamping rod (404), and the T-shaped slot (411) and the T-shaped clamping block (410) are clamped together.

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