Methods and Apparatus for Pulsed Electrical Field Neuromodulation Via an Intra-to-Extravascular Approach

a pulsed electrical field and intra-to-extravascular approach technology, applied in the field of medical devices and methods, can solve problems such as sedation of patients, and achieve the effect of treating or reducing pain

Inactive Publication Date: 2008-07-17
CVRX
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0015]Activating the baroreflex may involve electrical activation, mechanical activation, thermal activation, chemical activation, some combination thereof, or any other suitable type of activation. In various embodiments, activation may be either continuous, pulsed or periodic. In one embodiment, activating the baroreflex system not only treats or reduces pain but also causes sedation of the patient.

Problems solved by technology

In one embodiment, activating the baroreflex system not only treats or reduces pain but also causes sedation of the patient.

Method used

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  • Methods and Apparatus for Pulsed Electrical Field Neuromodulation Via an Intra-to-Extravascular Approach
  • Methods and Apparatus for Pulsed Electrical Field Neuromodulation Via an Intra-to-Extravascular Approach
  • Methods and Apparatus for Pulsed Electrical Field Neuromodulation Via an Intra-to-Extravascular Approach

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Embodiment Construction

[0058]Referring now to FIG. 1, within the arterial walls of the aortic arch 12, common carotid arteries 14 / 15 (near the right carotid sinus 20 and left carotid sinus), subclavian arteries 13 / 16 and brachiocephalic artery 22 there are baroreceptors 30. For example, as best seen in FIG. 2A, baroreceptors 30 reside within the vascular walls of the carotid sinus 20. Baroreceptors 30 are a type of stretch receptor used by the body to sense blood pressure. An increase in blood pressure causes the arterial wall to stretch, and a decrease in blood pressure causes the arterial wall to return to its original size. Such a cycle is repeated with each beat of the heart. The baroreceptors 30 located in the right carotid sinus 20, the left carotid sinus and the aortic arch 12 play the most significant role in sensing blood pressure that affects the baroreflex system 50, which is described in more detail with reference to FIG. 2B.

[0059]Refer now to FIG. 2B, which shows a schematic illustration of b...

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Abstract

The present invention is an apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach. The apparatus includes a pulsed electric field generator and at least one electrode electrically coupled to the pulsed electric field generator. The electrode is configured for intravascular delivery, and extravascular placement, via an intra-to-extravascular approach. The electrode is configured for extravascular delivery of a pulsed electric field to induce neuromodulation.

Description

CROSS-REFERENCES TO RELATED APPLICATIONS[0001]This application is a continuation of U.S. patent application Ser. No. 10 / 970,829, filed on Oct. 20, 2004, which claims the benefit of U.S. Provisional Patent Application No. 60 / 513,642, the disclosures of each being hereby incorporated by reference in their entirety.BACKGROUND OF THE INVENTION[0002]1. Field of the Invention[0003]The present invention relates generally to medical devices and methods. More specifically, the invention relates to devices and methods for activating the baroreflex system to treat or reduce pain control and / or to cause or enhance sedation or sleep.[0004]Pain is one of the oldest and least understood medical mysteries. Pain is defined by the Merriman-Webster Dictionary as: (1) localized physical suffering associated with bodily disorder, such as a disease or injury; or (2) a basic bodily sensation induced by a noxious stimulus, received by naked nerve endings, characterized by physical discomfort (as pricking, ...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61N1/04A61N1/00A61N1/34A61N1/36
CPCA61N1/0556A61N1/08A61N1/36114A61N1/36071
Inventor KIEVAL, ROBERT S.ROSSING, MARTIN
Owner CVRX
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