A handheld glycosylated hemoglobin analyzer, system and detection method

Abstract

The present invention relates to the technical field of medical detection equipment, and specifically to a handheld glycated hemoglobin analyzer, system and detection method, comprising a lower shell, an upper shell installed on the lower shell and a hatch cover rotatably installed on the upper shell, a glycated hemoglobin detection mechanism for detecting a detection card after sample addition is installed in the cavity formed by the upper shell and the lower shell, a tray driving mechanism linked to the hatch cover is also installed on the lower shell, and the tray driving mechanism realizes the detection card tray to enter and exit the glycated hemoglobin detection mechanism according to the opening and closing of the hatch cover, so as to solve the technical problems of glycated hemoglobin analysis equipment in the prior art, such as complex structure, large occupied space, high manufacturing cost, complex operation, long reporting cycle and inconvenient carrying.

Description

Technical Field

[0001] The present invention relates to the technical field of medical detection equipment, and in particular to a handheld glycosylated hemoglobin analyzer, system and detection method. Background Art

[0002] Glycated hemoglobin (HbA1c) has good stability and is not affected by occasional increase or decrease in blood sugar. It can objectively reflect the average blood sugar level of diabetic patients in the past 2 to 3 months. At the same time, it is closely related to diabetic complications, especially microvascular diseases, and has important clinical value in the clinical diagnosis and disease monitoring of diabetes.

[0003] At present, the glycated hemoglobin instruments on the market are often complex in structure, occupy a large space, have high manufacturing costs, complex operations, long reporting cycles, and the matching reaction kits are also relatively expensive. Therefore, these instruments are difficult to be popularized in community clinics, pharmacy clinics, and even families. In summary, the market is in urgent need of a practical small glycated hemoglobin analyzer that is easy to operate, low in cost, reliable in performance, and easy to carry. Summary of the invention

[0004] In view of the deficiencies in the prior art, the present invention provides a handheld glycosylated hemoglobin analyzer, system and detection method to solve the technical problems of the prior art glycosylated hemoglobin analysis equipment, such as complex structure, large space occupation, high manufacturing cost, complex operation, long reporting cycle and inconvenient carrying.

[0005] The technical solution of the present invention to solve the above technical problems is as follows: a handheld glycated hemoglobin analyzer comprises a lower shell, an upper shell installed on the lower shell and a hatch cover rotatably installed on the upper shell by a rotating shaft, a glycated hemoglobin detection mechanism for detecting a test card after sample addition is installed in the cavity formed by the upper shell and the lower shell, and a tray driving mechanism linked to the hatch cover is also installed on the lower shell, and the tray driving mechanism realizes the test card tray entering and exiting the glycated hemoglobin detection mechanism according to the opening and closing of the hatch cover.

[0006] Based on the above technical solution, the present invention can also be improved as follows.

[0007] Furthermore, the tray driving mechanism includes two connecting rods, one end of the two connecting rods is rotatably connected to both sides of one end of the hatch, and the other end of the two connecting rods is rotatably connected to the detection card tray, and both sides of the detection card tray are slidably installed on the limiting guide rails of the lower shell.

[0008] Furthermore, a card slot matching the shape and size of the test card is provided in the test card tray, and a vent and a sample addition port are provided on the test card.

[0009] Furthermore, the upper shell body is vertically slidably installed with an air nozzle push rod, and the bottom end of the air nozzle push rod is installed with an air nozzle for connecting with the air port of the detection card. The air nozzle is located directly above the air port of the detection card after entering the glycated hemoglobin detection mechanism. The top of the air nozzle push rod protrudes from the upper shell body, and is pressed down when the hatch is closed so that the air nozzle is sealed and connected with the air port. A spring is installed on the air nozzle push rod for resetting the air nozzle push rod when the hatch is opened.

[0010] Furthermore, a main control board and a micro pump module electrically connected to the main control board are installed on the bottom surface of the upper shell, a touch display screen and buttons electrically connected to the main control board are installed on the surface of the upper shell, an optical detection module and a signal acquisition board are installed on the upper surface of the lower shell, the optical detection module is electrically connected to the main control board through the signal acquisition board, and a USB interface is also provided on the lower shell, which is electrically connected to the main control board.

[0011] Furthermore, the micro pump module includes a micro pump and an air circuit, the air circuit is connected to the air nozzle ejector rod, and the micro pump is powered by a battery installed on the lower housing.

[0012] Furthermore, a hatch cover lock buckle is installed at the free end of the hatch cover, and a lock groove matching with the hatch cover lock buckle is installed on the lower shell body.

[0013] A handheld glycosylated hemoglobin analysis system, the system comprising a main control board, an optical detection module, a signal acquisition board, a touch display screen and buttons;

[0014] The main control board includes power control, touch screen control, temperature control, gas circuit control, data and signal processing and data communication functions;

[0015] The optical detection module is used to measure and obtain the minute changes of multiple samples to be tested in the whole reaction process in real time, and convert them into digital signals for easy processing;

[0016] The signal acquisition board is used to collect the digital signals output by one or more optical detection modules in real time and pre-process the data;

[0017] The touch screen is used for information entry, operation guidance, status prompts and result display;

[0018] The buttons include a power button and a test button, and the test button is a shortcut button.

[0019] Furthermore, the temperature control function is used to control the heating module hidden inside the test card tray so as to maintain the sample to be tested in the test card at a preset constant temperature, and the communication function is used to connect to external devices and supports connection with external devices via a wireless network.

[0020] A detection method for a handheld glycated hemoglobin analyzer, the method comprising the following steps: S1: long pressing a power button, and the analyzer will self-check and wait for operation after being powered on; S2: starting the test after entering the patient information to be tested using a touch display screen; S3: pressing and opening a hatch cover according to the prompt, and a test card tray slides out; S4: after loading a glycated hemoglobin test card, dripping a sample to be tested into a sample addition port of the test card according to the prompt; S5: closing the hatch cover, and at the same time, the test card tray carries the test card into an optical detection module inside an upper shell, and at the same time, the hatch cover presses down a nozzle push rod to connect the nozzle with the air vent of the test card; S6: clicking a test button, the instrument enters a test operation, and completes the flow of the sample to be tested in a flow channel in the test card, sample processing, quantitative distribution to a designated area, reaction and detection process; S7: after the test is completed, the test result is displayed, and a report is printed; S8: opening the hatch cover, taking out the test card, and completing the test task.

[0021] The beneficial effects of the present invention are: 1. Simple operation, fast result reporting, and the glycated hemoglobin test can be completed within 10 minutes without the need for a professional physician; 2. Light weight, small size, rechargeable, easy to carry, simple structure, extremely low cost, high reliability, and a wide range of uses. It is especially suitable for community clinics, pharmacy clinics, homes, etc., and is the best instrument solution under my country's tiered diagnosis and treatment policy. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 It is a front perspective stereoscopic schematic diagram of the present invention;

[0023] Figure 2 A three-dimensional schematic diagram of the front view hatch cover of the present invention being opened;

[0024] Figure 3 This is a schematic diagram of loading the test card of the present invention;

[0025] Figure 4 It is a partial schematic diagram of the present invention;

[0026] Figure 5 It is a schematic diagram of the internal structure of the present invention;

[0027] Figure 6 It is a left side cross-sectional view of the present invention when the test card is loaded;

[0028] Figure 7 It is a left side cross-sectional view during detection of the present invention;

[0029] Figure 8 It is a three-dimensional schematic diagram of the present invention from a rear perspective;

[0030] Fig. 9 This is a partial schematic diagram of the air nozzle push rod installation.

[0031] In the figure, 1. upper shell, 2. lower shell, 3. hatch, 4. touch display screen, 5. button, 6. test card tray, 7. hatch lock, 8. air nozzle push rod, 9. test card, 10. sample addition port, 11. vent, 12. air nozzle, 13. optical detection module, 14. signal acquisition board, 15. battery, 16. micro pump module, 17. main control board, 18. connecting rod, 19. USB interface, 20. rotating shaft, 21. slide slot, 22. partition, 23. ring table, 24. spring. DETAILED DESCRIPTION

[0032] The principles and features of the present invention are described below in conjunction with the accompanying drawings. The examples given are only used to explain the present invention and are not used to limit the scope of the present invention.

[0033] See attached Figure 1 A handheld glycated hemoglobin analyzer comprises a lower shell 2, an upper shell 1 mounted on the lower shell 2, and a hatch 3 rotatably mounted on the upper shell 1 via a rotating shaft 20. A glycated hemoglobin detection mechanism for detecting a sampled detection card 9 is installed in a cavity formed by the upper shell 1 and the lower shell 2. A tray driving mechanism linked to the hatch 3 is also installed on the lower shell 2. The tray driving mechanism enables the detection card tray 6 to enter and exit the glycated hemoglobin detection mechanism according to the opening and closing of the hatch 3. Specifically, when the hatch 3 is opened, the detection card tray 6 slides out to facilitate the loading of the glycated hemoglobin detection card 9. When the hatch 3 is closed, the detection card tray 6 slides in, and the glycated hemoglobin detection card 9 can be moved to the optical detection module 13 to realize the glycated hemoglobin detection work.

[0034] See attached Figure 2-4And 6-7, the tray driving mechanism includes two connecting rods 18, one end of the two connecting rods 18 is rotatably connected to the two sides of one end of the hatch 3 respectively, and the other end of the two connecting rods 18 is rotatably connected to the two sides of the detection card tray 6, and the slide grooves 21 at the bottom of both sides of the detection card tray 6 are slidably installed on the limiting guide rails of the lower shell 2. By pulling or pushing the connecting rods 18, the detection card tray 6 is translated along the limiting guide rails on the lower shell 2 to complete the entry and exit action; a card slot matching the shape and size of the detection card 9 is arranged in the detection card tray 6, and a vent 11 and a sample addition port 10 for dripping the sample to be tested are arranged on the detection card 9. When testing, the hatch 3 is closed, and the hatch 3 presses down the air nozzle push rod 8 at the same time. The air nozzle push rod 8 drives the air nozzle 12 to fit tightly with the vent 11 of the detection card 9 to complete the air path connection, which is used to provide a flow driving force for the liquid in the flow channel of the detection card 9 for the sample to be tested. The upper shell 1 is vertically slidably installed with an air nozzle push rod 8, and the bottom end of the air nozzle push rod 8 is installed with an air nozzle 12 for communicating with the air vent 11 of the detection card 9. The air nozzle 12 is located directly above the air vent 11 of the detection card 9 after entering the glycated hemoglobin detection mechanism. The top of the air nozzle push rod 8 protrudes from the upper shell 1, and is pressed down when the hatch cover 3 is closed so that the air nozzle 12 is sealed and connected with the air vent 11. A spring 24 for resetting the air nozzle push rod 8 when the hatch cover 3 is opened is installed on the air nozzle push rod 8. The spring 24 is installed below the ring platform 23 of the air nozzle push rod 8 and above the partition 22 of the upper shell 1. When the hatch cover 3 is open, under the action of the spring 24, the air nozzle push rod 8 is reset so that the air nozzle 12 is pressed below the partition 22. When the hatch cover 3 is closed, the spring 24 is compressed, and the air nozzle 12 descends and is sealed and connected with the air vent 11 of the detection card 9.

[0035] See attached Figure 5 The main control board 17 and the micro pump module 16 connected to the main control board 17 by electrical signals are installed on the bottom surface of the upper housing 1. The touch screen 4 and the key 5 connected to the main control board 17 by electrical signals are installed on the surface of the upper housing 1. The optical detection module 13 and the signal acquisition board 14 for realizing multi-wavelength detection are installed on the upper surface of the lower housing 2. The optical detection module 13 is connected to the main control board 17 by electrical signals through the signal acquisition board 14. A USB interface 19 is also provided on the rear side of the lower housing 2, and the USB interface 19 is electrically connected to the main control board 17. The micro pump module 16 includes a micro pump and an air circuit, which is connected to the air nozzle push rod 8, and the micro pump is powered by a battery 15 installed on the lower housing 2.

[0036] See attached Figure 3 A hatch cover lock buckle 7 is installed at the free end of the hatch cover 3, and a lock groove matching with the hatch cover lock buckle 7 is installed on the lower shell body 2.

[0037] Participate in the Figure 5, a handheld glycosylated hemoglobin analysis system, the system includes a main control board 17, an optical detection module 13, a signal acquisition board 14, a touch screen 4 and a button 5; the main control board 17 includes power control, touch screen control, temperature control, gas circuit control, data and signal processing and data communication functions; the optical detection module 13 is used to measure and obtain the slight changes of multiple test samples in the whole reaction process in real time, and convert them into digital signals that are easy to process; the signal acquisition board 14 is used to collect one or more digital signals output by the optical detection module 13 in real time, and pre-process the data; the touch screen 4 is used for information entry, operation guidance, status prompts and result display; the button 5 includes a power on / off button and a test button, and the test button is a shortcut button. The temperature control function is used to control the heating module hidden in the test card tray 6, so as to maintain the test sample in the test card 9 at a preset constant temperature, and the communication function is used to connect external devices, and supports connection with external devices through a wireless network.

[0038] A detection method for a handheld glycated hemoglobin analyzer, the method comprising the following steps: S1: long press a power button 5, wait for the analyzer to be powered on and then self-check and wait for operation; S2: start the test after entering the patient information to be tested using a touch display screen 4; S3: press and open the hatch 3 according to the prompt, and the test card tray 6 slides out; S4: after loading the glycated hemoglobin test card 9, drip the sample to be tested into the sample addition port 10 of the test card 9 according to the prompt; S5: close the hatch 3, and at the same time, the test card tray 6 carries the test card 9 into the optical detection module 13 inside the upper shell 1, and at the same time, the hatch 3 presses down the air nozzle push rod 8 to connect the air nozzle 12 with the air vent 11 of the test card 9; S6: click the test button, the instrument enters the test operation, and completes the flow of the sample to be tested in the flow channel in the test card 9, sample processing, quantitative distribution to the designated area, reaction and detection process; S7: after the test is completed, the test result is displayed, and a report is printed; S8: open the hatch 3, take out the test card 9, and complete the test task.

[0039] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A handheld glycated hemoglobin analyzer, characterized in that: It comprises a lower shell, an upper shell mounted on the lower shell, and a hatch cover rotatably mounted on the upper shell, a glycosylated hemoglobin detection mechanism for detecting the test card after the sample is loaded is installed in the cavity formed by the upper shell and the lower shell, and a tray driving mechanism linked with the hatch cover is also installed on the lower shell, and the tray driving mechanism realizes the test card tray entering and exiting the glycosylated hemoglobin detection mechanism according to the opening and closing of the hatch cover; The tray driving mechanism includes two connecting rods, one end of the two connecting rods is rotatably connected to both sides of one end of the hatch cover, and the other end of the two connecting rods is rotatably connected to the detection card tray, and both sides of the detection card tray are slidably mounted on the limit guide rails of the lower shell; A card slot matching the shape and size of the test card is arranged in the test card tray, and a vent and a sample adding port are arranged on the test card; The upper shell body is vertically slidably installed with an air nozzle push rod, and the bottom end of the air nozzle push rod is installed with an air nozzle used to be connected with the air port of the detection card. The air nozzle is located directly above the air port of the detection card after entering the glycated hemoglobin detection mechanism. The top of the air nozzle push rod protrudes from the upper shell body, and is pressed down when the hatch is closed to make the air nozzle and the air port sealed and connected. A spring is installed on the air nozzle push rod to reset the air nozzle push rod when the hatch is opened.

2. A handheld glycated hemoglobin analyzer according to claim 1, characterized in that: The main control board and the micro pump module connected to the main control board electrical signal are installed on the bottom surface of the upper shell, the touch display screen and buttons connected to the main control board electrical signal are installed on the surface of the upper shell, and the optical detection module and the signal acquisition board are installed on the upper surface of the lower shell. The optical detection module is connected to the main control board electrical signal through the signal acquisition board. A USB interface is also arranged on the lower shell, and the USB interface is electrically connected to the main control board.

3. A handheld glycated hemoglobin analyzer according to claim 2, characterized in that: The micro pump module comprises a micro pump and an air circuit, the air circuit is communicated with the air nozzle ejector rod, and the micro pump is powered by a battery installed on the lower housing.

4. A handheld glycated hemoglobin analyzer according to any one of claims 1 to 3, characterized in that: A hatch cover lock buckle is installed at the free end of the hatch cover, and a lock groove matched with the hatch cover lock buckle is installed on the lower shell body.

5. A handheld glycosylated hemoglobin analysis system, the system is based on a handheld glycosylated hemoglobin analyzer according to any one of claims 1 to 4, characterized in that: The system includes a main control board, an optical detection module, a signal acquisition board, a touch screen and buttons; the main control board includes power control, touch screen control, temperature control, gas circuit control, data and signal processing and data communication functions; the optical detection module is used to measure and obtain the slight changes of multiple samples to be tested in the whole reaction process in real time, and convert them into digital signals that are easy to process; the signal acquisition board is used to collect the digital signals output by one or more optical detection modules in real time, and pre-process the data; the touch screen is used for information entry, operation guidance, status prompts and result display; the buttons include a power on / off button and a test button, and the test button is a shortcut button.

6. A handheld glycosylated hemoglobin analysis system according to claim 5, characterized in that: The temperature control function is used to control the heating module hidden inside the test card tray so as to maintain the sample to be tested in the test card at a preset constant temperature. The communication function is used to connect to external devices and supports connection with external devices via a wireless network.

7. A detection method for a handheld glycosylated hemoglobin analyzer, the detection method being based on a handheld glycosylated hemoglobin analyzer according to any one of claims 1 to 4, characterized in that: The method comprises the following steps: S1: long pressing the power button, and the analyzer will self-check and wait for operation after being powered on; S2: starting the test after entering the patient information to be tested using the touch screen; S3: pressing and opening the hatch cover according to the prompt, and the test card tray slides out; S4: after loading the glycated hemoglobin test card, dripping the test sample into the sample injection port of the test card according to the prompt; S5: closing the hatch cover, and at the same time, the test card tray carries the test card into the optical detection module inside the upper shell, and at the same time, the hatch cover presses down the air nozzle push rod to connect the air nozzle with the air vent of the test card; S6: clicking the test button, the instrument enters the test operation, and completes the flow of the test sample in the flow channel in the test card, sample processing, quantitative distribution to the designated area, reaction and detection process; S7: after the test is completed, the test result is displayed, and a report is printed; S8: opening the hatch cover, taking out the test card, and completing the test task.

Images