Medication status management device, method, and computer-readable recording medium having program recorded thereon

Abstract

In order to more accurately manage medication, one scheme of the present invention obtains declaration information related to a user's medication, and obtains the user's biometric information and stores it in a storage medium. Based on the biometric information stored in the storage medium, the dispersion of the biometric information obtained during the object period is calculated, and the reliability of the declaration information related to medication obtained during the object period is determined based on the dispersion of the biometric information, and information representing the determination result of the reliability is output.

Description

Technical Field

[0001] Embodiments of the present invention relate to a medication-taking situation management device, method, and program for managing medication-taking situation by, for example, a user. Background Art

[0002] One of the treatment methods for diseases is medication. In medication, it is very important to follow the medication prescribed by the doctor in order to obtain the expected therapeutic effect.

[0003] Therefore, the following technology has been proposed: for example, a patient uses a portable information terminal such as a smartphone to input declaration information indicating whether or not the patient has taken the medication, and based on the declaration information, medication adherence information indicating the compliance with medication is generated, and the information can be displayed on the patient's terminal and the doctor's or pharmacist's terminal (for example, refer to Patent Document 1).

[0004] If this technology is used, then, for example, doctors, pharmacists and other medication managers can accurately grasp the relationship between the patient's medication and the treatment effect, which is very effective. In addition, for patients, it will also become one of the motivations for continuing their medication.

[0005] Prior art literature

[0006] Patent Literature

[0007] Patent Document 1: Japanese Patent Application Publication No. 2018-151993 Summary of the invention

[0008] Problem that the invention aims to solve

[0009] On the other hand, among patients who take medication while carrying out their daily lives at home, there are patients who not only fail to take medication as indicated on the prescription, but also report falsely claiming that they have taken medication due to reasons such as low awareness of compliance with medication or being busy. In this case, in the above-mentioned prior art, it is impossible to check whether the medication report made by the patient has actually been taken, so doctors, pharmacists and other medication managers may not be able to correctly judge the relationship between medication and its therapeutic effect. This is also likely to lead to erroneous medication judgments such as increasing the dosage or changing the medicinal materials, which is very undesirable.

[0010] The present invention has been made in view of the above-mentioned situation, and an object of the present invention is to provide a technology for providing information for more accurately managing medication status.

[0011] Technical Solution

[0012] In order to solve the above-mentioned problems, a scheme of the medication status management device or method of the present invention adopts a method of obtaining declaration information related to a user's medication, and obtaining biological information of the user, storing it in a storage medium, calculating the dispersion degree of the biological information obtained during the object period based on the biological information stored in the storage medium, judging the reliability of the declaration information related to medication obtained during the object period based on the dispersion degree of the biological information, and outputting information representing the judgment result of the reliability.

[0013] Effects of the Invention

[0014] According to one scheme of the present invention, the following effects are exerted. That is, generally, the dispersion degree of biological information is correlated with the compliance of medication. For example, from the dispersion degree of blood pressure values ​​measured regularly every day during a target period of one week, there is a tendency that the dispersion degree of blood pressure values ​​of patients who comply with medication is small, while conversely, the dispersion degree of blood pressure values ​​of patients who do not comply with medication is large. Therefore, as in the first scheme of the present invention, the dispersion degree of measured values ​​of biological information such as blood pressure during the target period is calculated, and based on the dispersion degree, the reliability of medication declaration is determined and output, thereby, for example, doctors and pharmacists can accurately infer the medication status of users as patients and diagnose the effect of medication.

[0015] That is, according to one aspect of the present invention, it is possible to provide a technology for providing information for more accurately managing medication taking. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 This is a functional block diagram showing an application example of the medication status management device of the present invention.

[0017] Figure 2 It is a diagram showing the overall configuration of a system including a portable information terminal as a first embodiment of the medication schedule management device of the present invention.

[0018] Figure 3 Yes means Figure 2 A diagram showing an example of the hardware configuration of a portable information terminal.

[0019] Figure 4 Yes means Figure 2 A diagram showing an example of the software configuration of a portable information terminal.

[0020] Figure 5 It means by Figure 4 A flowchart showing the procedure and content of medication status management processing performed by a portable information terminal.

[0021] Figure 6 Yes means Figure 5The flowchart shown is a flowchart of an example of the sequence and processing content of the medication report reliability determination processing.

[0022] Figure 7 It is a diagram showing an example of the software configuration of a portable information terminal as the second embodiment of the medication schedule management device of the present invention.

[0023] Figure 8 It means by Figure 7 A flowchart showing the procedure and content of medication status management processing performed by a portable information terminal.

[0024] Fig. 9 Yes means Figure 8 The flowchart shown is a flowchart of an example of the sequence and processing content of the medication report reliability determination processing.

[0025] Fig.10 This is a diagram showing an example of an input template displayed on a user terminal when inputting a report of taking medication. DETAILED DESCRIPTION

[0026] Hereinafter, an embodiment of one aspect of the present invention will be described based on the drawings. However, the embodiment described below is merely an example of the present invention in all aspects.

[0027] [Application Examples]

[0028] First, an application example of the medication status management device of the present invention will be described. Figure 1 UT is a diagram for explaining one application example, and BP represents a blood pressure monitor. UT represents a user terminal and BP represents a blood pressure monitor.

[0029] (Configuration example)

[0030] (1) Blood pressure monitor

[0031] The sphygmomanometer BP is, for example, a fixed type or upper arm-worn type sphygmomanometer that measures blood pressure by an oscillometric method, and has a function of sending blood pressure measurement data to the user terminal UT by using a wireless communication circuit that uses a short-range wireless data communication standard such as Bluetooth (registered trademark). It should be noted that, as a sphygmomanometer, in addition to a fixed type or upper arm-worn type that measures blood pressure by wrapping a cuff around the upper arm, a wrist type or watch type sphygmomanometer may also be used. If a watch type sphygmomanometer is used, blood pressure can be measured intermittently or automatically at a preset time.

[0032] (2) User Terminal UT

[0033] The user terminal UT is composed of a portable information terminal such as a smartphone carried by a user who is a patient, and as a function of an application example of the present invention, it has: an input / display device 100, a blood pressure measurement data acquisition unit 200, a dispersion degree calculation unit 300, a medication report information acquisition unit 400, a medication report reliability determination unit 500, a determination information output unit 600 and a wireless communication circuit 700.

[0034] Among them, the blood pressure measurement data acquisition unit 200, the dispersion degree calculation unit 300, the medication report information acquisition unit 400, the medication report reliability determination unit 500, and the determination information output unit 600 are realized by causing a hardware processor to execute a program, for example.

[0035] The input / display device 100 is a tablet-type device having a capacitive or pressure-sensitive input detection sheet arranged on a liquid crystal or organic EL screen, and outputs the medication report information input by the user's operation to the medication report information acquisition unit 400. The medication report information acquisition unit 400 acquires the medication report information output from the input / display device 100 and stores it in a memory in the user terminal UT.

[0036] The wireless communication circuit 700 has multiple wireless interface functions for communicating between a wide area mobile communication network, a wireless LAN (Local Area Network), and Bluetooth (registered trademark). In this example, it is used to receive blood pressure measurement data sent from the above-mentioned blood pressure monitor BP, and to send judgment information on the reliability of medication declaration information input by the user to the terminal of medication managers such as doctors and pharmacists.

[0037] The blood pressure measurement data acquisition unit 200 acquires the blood pressure measurement data received via the wireless communication circuit 700 and stores the acquired data in a memory in the user terminal UT.

[0038] The dispersion calculation unit 300 reads the blood pressure measurement data measured during a preset target period (eg, one day or one week) from the memory, and calculates the dispersion (eg, the degree of variation in the measured values ​​or the degree of variation in the changes in the measured values).

[0039] The medication report information acquisition unit 400 acquires information on medication status during the medication report period input by the user in the input / display device 100, and stores the information in a memory in the user terminal UT.

[0040] The medication report reliability determination unit 500 determines the reliability of the medication report information input by the user based on the dispersion degree of the blood pressure measurement data calculated by the dispersion degree calculation unit 300. The reliability determination is performed based on, for example, the number of times (timing) of medication to be taken in a day specified by the prescription information and the content thereof. The prescription information is obtained from, for example, a doctor's or pharmacist's terminal or a hospital's EMS server and stored in the storage unit 800.

[0041] The determination information output unit 600, for example, generates a notification message for reporting the determination result of the reliability of the medication declaration information to the medication manager such as a doctor or a pharmacist based on the determination result of the reliability of the medication declaration information, and sends it to the terminal of the doctor or the pharmacist from the wireless communication circuit 700. In addition, the determination information output unit 600 also has a function of generating a notification message for urging the user to declare medication and displaying it on the input / display device 100. It should be noted that the determination information output unit 600 may also have a function of generating the result of the determination of the reliability of the medication declaration information, for example, generating a contact message for family members when the reliability is lower than a threshold, and sending it from the wireless communication circuit 700.

[0042] (Effect)

[0043] Due to the above configuration, in the user terminal UT, the medication report information acquisition unit 400 acquires the medication report information of the user during the medication period, and the blood pressure measurement data acquisition unit 200 acquires the blood pressure measurement data of the user. Then, based on the acquired blood pressure measurement data, the blood pressure value or the dispersion degree of the change of the blood pressure measurement data during the period is calculated in units of one day or one week, and based on the calculated dispersion degree of the blood pressure value, the medication report reliability determination unit 500 determines the reliability of the medication report information of the user during the same period, and the determination information indicating the determination result is output from the determination information output unit 600.

[0044] Here, generally, the dispersion of blood pressure values ​​is correlated with the compliance of medication. For example, from the dispersion of blood pressure values ​​measured regularly every day during a target period of one week, there is a tendency that the dispersion of blood pressure values ​​of patients who comply with medication is small, while conversely, the dispersion of blood pressure values ​​of patients who do not comply with medication is large.

[0045] Therefore, as described above, the reliability of the medication report is determined based on the degree of dispersion of blood pressure values ​​within the target period, and the result is sent to the medication manager terminal. Thus, medication managers such as doctors and pharmacists can accurately infer the medication status of users as patients and diagnose the effectiveness of the medication.

[0046] In addition, the following application examples are also considered in the medication schedule management device of the present invention.

[0047] For example, a medication status management device includes: a declaration information acquisition unit, which acquires declaration information related to a user's medication and stores it in a storage medium; a biological information acquisition unit, which acquires the biological information of the user and stores the biological information in the storage medium in a state in which the declaration information and the information corresponding to the acquisition timing thereof can be associated with each other; a prediction unit, which calculates a predicted value of the biological information in a second period that becomes a monitoring object of the biological information based on the declaration information and the biological information in a first period in which the medication status is known and stored in the storage medium; a calculation unit, which calculates the degree of deviation of the actual value of the biological information acquired in the second period from the calculated predicted value of the biological information; a reliability judgment unit, which judges the reliability of the declaration information related to medication in a third period before the second period that affects the change of the biological information in the second period based on the calculated deviation; and an output unit, which outputs information indicating the result of the reliability judgment.

[0048] According to such a configuration, the following effects are achieved. That is, generally, considering that the actual measured value of the biological information of a user who complies with medication has a small change relative to the predicted value, there is a tendency that the predicted value of the biological information in the second period (monitoring period of biological information) predicted based on the biological information measured in the first period (prediction reference period) when the medication status is known and the reported information of medication and the actual measured value of the biological information actually measured in the second period deviates less. On the other hand, in the case where a user who does not comply with medication has reported medication as if he complied with medication, the predicted value of the biological information in the second period, which is estimated to show the efficacy of the medicine, deviates more from the actual measured value of the biological information actually measured.

[0049] Therefore, as in this application example, based on the biological information and the reported information on medication obtained during the first period in which the past medication status is known, the value of the biological information during the second period, which is the monitoring period of the biological information, is predicted, and based on the degree of deviation of the actually measured value of the biological information from the predicted value, the reliability of the reported information on medication during the third period before the second period, which affects the change of the biological information during the second period, is judged, and the result is output, thereby, for example, doctors, pharmacists and other medication managers can more accurately grasp the medication status of users as patients during the medication period.

[0050] For example, the medication status management device determines, through the reliability determination unit, whether the dispersion degree of the biological information calculated by the calculation unit or the deviation degree of the actual measured value of the biological information relative to the predicted value is higher or lower than a threshold value. When the reliability determination unit determines that the dispersion degree or the deviation degree of the biological information is higher than the threshold value, the output unit generates a message urging correct medication or reporting of medication, and outputs the message to at least one of the terminal of the user and the terminal of a person having a prescribed relationship with the user.

[0051] According to such a configuration, when it is determined that the dispersion or deviation of the biological information is higher than the threshold value, a message urging the user to take or report the medication correctly is generated and output to the user's terminal or the terminal of a relative or other person who has a predetermined relationship with the user. Therefore, the user can be more reliably enlightened to take or report the medication correctly.

[0052] For example, the medication status management device calculates, through the reliability determination unit, based on the reported information related to medication, a medication rate that represents the ratio of the number of times the medication is reported to have been taken to the total number of times the medication is reported to have been taken during the reporting period, and sets the threshold value based on the calculated medication rate so that the lower the medication rate, the higher the value.

[0053] According to such a configuration, the threshold is set so that the lower the medication taking rate is, the higher the threshold is. Therefore, when the user reports that he / she has taken the medication even though he / she has not actually taken the medication, a more accurate determination can be made.

[0054] For example, the medication status management device determines through the reliability judgment unit whether the declaration information related to medication contains any missing declaration information based on the declaration information related to medication, and if it is determined that there is a missing declaration information, it is determined that the user needs to be urged to make a declaration related to medication.

[0055] According to such a configuration, when it is determined that the declaration information input by the user is incomplete, it is determined that the user needs to be urged to make a declaration related to taking medicine. Therefore, before determining the reliability of the declaration information, the user can be urged to make a complete declaration of taking medicine.

[0056] For example, when the medication status management device determines that it is necessary to urge the user to make a declaration related to medication, it outputs information urging the user to make a declaration related to medication, and determines whether the user has responded to the prompt for the information urging the user to make the declaration related to medication. If it is determined that the user has not responded, it is deemed that the declaration related to medication has not been made, and the reliability determination processing of the declaration information is omitted.

[0057] According to such a configuration, when the user does not input a medication declaration in response to the urging of medication declaration, it is deemed that there is no medication declaration, and the reliability determination process of the declaration information is not performed. Therefore, the processing load of the device can be reduced when valid declaration information is not input.

[0058] For example, the medication status management device also includes: a medication rate calculation unit, which calculates the medication rate representing the ratio of the number of times the medication is reported to have been taken to the total number of times the medication is reported within the reporting period based on the reported information related to the medication; and a correction unit, which corrects the medication rate based on the determination result of the reliability of the reported information performed by the reliability determination unit.

[0059] According to such a configuration, the medication rate is calculated based on the reported information of taking medication, and thus, for example, the medication rate is sent to the medication manager terminal, whereby the medication manager can further grasp the medication status of the user based on the value of the medication rate. Furthermore, the medication rate is corrected based on the reliability of the reported information, and thus, the correct medication rate can be identified that takes into account the user's reported errors and false reports.

[0060] For example, the medication record management device transmits information indicating the result of the reliability determination to a terminal used by a medication manager for the user through the output unit.

[0061] According to such a configuration, for example, a medication manager such as a doctor or a pharmacist can automatically obtain the reliability of the reported information on medication taken by the user, thereby contributing to, for example, reviewing the necessity of changing a prescription.

[0062] For example, the medication status management device stores the reliability determination result obtained by the reliability determination unit in the storage medium, and updates the reliability determination result stored in the storage medium every time a new reliability determination result is obtained.

[0063] According to such a configuration, the reliability of the medication report determined in the medication report reliability determination target period is temporarily continued until the reliability of the medication report is determined next time, that is, the reliability is maintained throughout the entire period after the determination target period until now.

[0064] [First embodiment]

[0065] (Configuration example)

[0066] (1) System

[0067] Figure 2UT is a diagram showing the overall configuration of a system including the medication management device according to the first embodiment of the present invention, wherein UT represents a user terminal as the medication management device, and BP represents a blood pressure monitor as a biological information measuring device.

[0068] The sphygmomanometer BP is, for example, a type of sphygmomanometer that wraps a cuff around the user's upper arm and measures the blood pressure value by the oscillometric method, and has a function of sending blood pressure measurement data to the user terminal UT via a short-range wireless network such as Bluetooth (registered trademark). As a sphygmomanometer BP, in addition to the type that wraps a cuff around the upper arm for measurement, a wrist-type or watch-type sphygmomanometer can also be used. Among them, the watch-type sphygmomanometer uses the oscillometric method or pulse wave transmission time (Pulse Transit Time; PTT) as a measurement method, and can measure blood pressure intermittently or automatically at a preset time. It should be noted that the sphygmomanometer BP and the user terminal UT can also be connected via other wireless networks such as a wireless LAN (Local Area Network) or a signal cable.

[0069] The user terminal UT can transmit data between the medication management terminal MT used by doctors or pharmacists and the family terminal FT used by the user's family via the network NW (Network). The network NW is composed of a wide area network with the Internet as the core and an access network for connecting terminals to the wide area network.

[0070] (2) User Terminal UT

[0071] (2-1) Hardware Configuration

[0072] Figure 3 This is a block diagram showing an example of the hardware configuration of the user terminal UT.

[0073] The user terminal UT is composed of a portable information terminal such as a smartphone or a tablet terminal carried by a user as a patient. The user terminal UT has a hardware processor 1 (hereinafter simply referred to as a CPU) such as a CPU (Central Processing Unit), and a memory 2, an input / display device 3, and a wireless communication circuit 4 are connected to the CPU 1 via a bus.

[0074] The memory 2 uses a memory obtained by combining a non-volatile memory such as an SSD (Solid State Drive) that can be written and read at any time and a volatile memory such as a RAM (Random Access Memory) as a storage medium, and has a program storage area and a data storage area in its storage area. The program storage area is used to store middleware programs and various application programs that function as an OS (Operation System). The data storage area is used to store various data used to determine the reliability of medication reporting information.

[0075] The input / display device 3 is composed of a tablet device provided with a capacitive or pressure-sensitive input sheet in addition to a display using, for example, liquid crystal or organic EL, and is used to input operation information performed by the user and display information.

[0076] The wireless communication circuit 4 has multiple wireless interface functions for wireless communication between short-distance wireless networks such as Bluetooth (registered trademark), local wireless networks within homes or enterprises such as wireless LAN, and public mobile communication networks provided by communication operators. Then, the blood pressure measurement data is received from the above-mentioned blood pressure meter BP via the short-distance wireless network, and data is transmitted between the medication manager terminal MT via the local wireless network or the public mobile communication network. It should be noted that the control of the wireless communication protocol is usually performed in the CPU 1, but it can also be set to be performed in the wireless communication circuit 4. It should be noted that 41 represents an antenna.

[0077] (2-2) Software composition

[0078] Figure 4 It is to combine the software structure of the user terminal UT with Figure 3 The hardware configuration shown is a block diagram shown in association with each other.

[0079] In the data storage area of ​​the memory 2, there are provided a medication declaration information storage unit 21, a blood pressure measurement data storage unit 22, and a prescription information storage unit 23. The medication declaration information storage unit 21 stores input template data used when the user inputs medication declaration information. In addition, in the medication declaration information storage unit 21, the medication declaration information input by the user through the input / display device 3 according to the above-mentioned input template data is associated with the information indicating the date and time of medication and stored. In the blood pressure measurement data storage unit 22, the blood pressure measurement data sent from the blood pressure monitor BP is associated with the information indicating the measurement date and time and stored. In the prescription information storage unit 23, for example, the user's prescription information downloaded from the medication manager terminal MT of a doctor, pharmacist, etc. or the EMR (Electronic Medical Records) server is stored.

[0080] The CPU 1, as a processing function unit of the first embodiment, includes a medication report information acquisition unit 11, a blood pressure measurement data acquisition unit 12, a dispersion degree calculation unit 13, a medication report reliability determination unit 14, and a determination information output unit 15. These control units 11 to 15 are all implemented by causing the CPU 1 to execute an application program stored in the program storage area in the memory 2.

[0081] The medication report information acquisition unit 11 is activated, for example, by an input request operation of medication report performed by a user, and reads the input template data from the medication report information storage unit 21 and displays it on the input / display device 3. Then, the medication report information acquisition unit 11 receives the medication report information input by the user according to the guidance of the input template data from the input / display device 3, associates the report information with the information indicating the date and time of medication, and stores it in the medication report information storage unit 21. It should be noted that the medication report information acquisition unit 11 can also be set to be activated according to the user's response operation to the message (reminder) urging the report of medication, for example.

[0082] The blood pressure measurement data acquisition unit 12 is activated by a data transmission request from the blood pressure monitor BP, and performs processing to associate the blood pressure measurement data transmitted from the blood pressure monitor BP and received via the wireless communication circuit 4 with information indicating the measurement date and time and store the data in the blood pressure measurement data storage unit 22 .

[0083] The dispersion degree calculation unit 13 reads the blood pressure measurement data including the measurement date and time during the determination target period from the blood pressure measurement data storage unit 22 every time a preset determination target period (for example, one day or one week) passes. Then, the dispersion degree calculation unit 13 calculates the dispersion degree of the blood pressure measurement data read out, for example, calculates the degree of deviation of the blood pressure measurement value or its change.

[0084] The medication report reliability determination unit 14 determines the reliability of medication report information within the same period input by the user based on the calculation result of the dispersion degree of the blood pressure measurement data obtained by the dispersion degree calculation unit 13. An example of reliability determination is described later.

[0085] The determination information output unit 15 generates notification information for notifying the medication manager, the user's family or the user himself of the determination result of the reliability of the medication report information performed by the above-mentioned medication report reliability determination unit 14, and sends the notification information to the medication manager terminal MT or the family terminal FT or displays it on the input / display device 3.

[0086] (Action Example)

[0087] Next, the operation of the user terminal UT configured as above will be described. Figure 5 and Figure 6 This is a flowchart showing an example of its operation.

[0088] (1) Obtaining medication reporting information

[0089] The user terminal UT monitors the operation of inputting the medication report information in step S10 in the standby state. In this state, the user clicks, for example, an icon assigned with the medication report function in the input / display device 3. In this way, the user terminal UT starts the medication report information acquisition unit 11. In step S11, first, the input template data is read from the medication report information storage unit 21 and displayed on the input / display device 3.

[0090] In this state, when the user inputs whether or not to take medicine after breakfast, lunch, or dinner on that day according to the above input template, the input / display device 3 receives the input information indicating whether or not to take medicine according to meals, and stores it in the medicine report information storage unit 21. At this time, the information indicating whether or not to take medicine is given information indicating the report date and time.

[0091] It should be noted that it is also conceivable that the user may summarize and input the declaration of medication for a day, for example, after dinner or before going to bed, or summarize and input it after the second day. In such a case, if the input date and time is directly used as the medication date and time, the reported medication date and time will be different from the actual medication date and time.

[0092] Therefore, in the above input template, for example, Fig.10As shown, check boxes 31a, 32a, 33a are provided for inputting whether or not to take medicine for the dates and times 30 that have not been input, corresponding to after breakfast, after lunch, and after dinner, respectively; and input fields 31b, 32b, 33b for the time of taking medicine are provided. Then, the information indicating whether or not to take medicine and the information indicating the time of taking medicine entered in the corresponding check boxes 31a, 32a, 33a and input fields 31b, 32b, 33b for breakfast, lunch, and dinner are stored in the medicine reporting information storage unit 21 as medicine reporting information. It should be noted that in Fig.10 The input template shown as an example displays the medicinal material 34 of the medication target. By displaying the medicinal materials, for example, a user who takes a plurality of types of medicines can input medication report information accurately for each medicinal material.

[0093] Thereafter, each time the user performs an input request operation for medication report, the user terminal UT receives the above-mentioned medication report information under the control of the medication report information acquisition unit 11 and performs a process of storing the above-mentioned medication report information in the medication report information storage unit 21 .

[0094] (2) Obtaining blood pressure measurement data

[0095] In the standby state, the user terminal UT monitors the request for sending the blood pressure measurement data from the blood pressure monitor BP in step S12. In this state, when receiving the request for sending the blood pressure measurement data from the blood pressure monitor BP, the user terminal UT starts the blood pressure measurement data acquisition unit 12, and in step S13, acquires the blood pressure measurement data sent from the blood pressure monitor BP and received through the wireless communication circuit 4 from the wireless communication circuit 4, and stores the blood pressure measurement data in the blood pressure measurement data storage unit 22. At this time, information indicating the measurement date and time is sent together with the blood pressure measurement data, so the user terminal UT associates the blood pressure measurement data with the measurement date and time and stores it in the blood pressure measurement data storage unit 22.

[0096] Thereafter, every time a transmission request is received from the blood pressure monitor BP, the user terminal UT performs the above-mentioned reception / storage processing of the blood pressure measurement data under the control of the blood pressure measurement data acquisition unit 12 .

[0097] (3) Calculation of the dispersion of blood pressure measurement data

[0098] While the user terminal UT performs the above-mentioned acquisition processing of the medication report information and the acquisition processing of the blood pressure measurement data, it monitors the determination request of the reliability of the medication report in step S14. In this state, when the above-mentioned determination request is generated from the soft timer of the CPU 1, for example, during the determination target period, for example, at the end time of a day or a week, the user terminal UT starts the dispersion degree calculation unit 13. Then, under the control of the dispersion degree calculation unit 13, in step S15, the blood pressure measurement data including the measurement date and time during the most recent determination target period are read from the blood pressure measurement data storage unit 22, and the dispersion degree of the blood pressure measurement data is calculated based on each of the read blood pressure measurement data.

[0099] The degree of dispersion can be calculated, for example, as the number or ratio of compression blood pressure values ​​that exceed the allowable blood pressure variation range centered on the standard deviation or dispersion of all compression blood pressure values ​​measured during the determination object period, the difference between the highest value and the lowest value among all compression blood pressure values, or the average value of all compression blood pressure values.

[0100] It should be noted that in the above example, the case where the determination request is generated at the end time point of the determination target period is described. However, this is not limited to this. For example, the determination request can also be sent from the medication manager terminal MT such as a doctor or pharmacist, or the family member terminal FT, and at the time point when the determination request is received, the dispersion of the blood pressure measurement value within a certain period (such as one day or one week) before the time is calculated.

[0101] (4) Determining the reliability of medication reporting

[0102] When calculating the dispersion of the blood pressure measurement data, the user terminal UT then starts the medication report reliability determination unit 14. Then, under the control of the medication report reliability determination unit 14, in step S16, the reliability of the medication report information corresponding to the determination target period stored in the medication report information storage unit 21 is determined.

[0103] Figure 6 1 is a flowchart showing an example of the order and content of the determination process of the reliability of the medication report. The medication report reliability determination unit 14 first reads the medication report information corresponding to the above-mentioned determination target period from the medication report information storage unit 21 in step S161, and determines whether certain medication reports are made based on the medication report information. In other words, it determines whether there are defects in the medication report.

[0104] For example, when the determination target period is one day, if the number of medication declarations specified by the prescription information stored in the prescription information storage unit 23 is even once, it is determined that there is no medication declaration on that day. In addition, for example, when the determination target period is one week, if the number of days without medication declaration is more than one day or more than a specified number of days, it is determined that there is no medication declaration in that week. Then, when it is determined that there is no medication declaration, the medication declaration reliability determination unit 14 regards the medication declaration information as a non-determination target for medication declaration reliability, and in step S162, it is determined that "it is necessary to urge the user to make a medication declaration", and the determination result is transmitted to the determination information output unit 15.

[0105] On the other hand, in the above step S161, when it is determined that there is a medication report, the medication report reliability determination unit 14 then determines in step S163 whether the dispersion degree of the blood pressure measurement data calculated by the dispersion degree calculation unit 13 is greater than the threshold value. As a result of this determination, if the dispersion degree is greater than the threshold value, the medication report reliability determination unit 14 determines in step S164 that the reliability of the medication report information during the above determination target period is "low". On the other hand, if the dispersion degree is less than the threshold value, the medication report reliability determination unit 14 determines in step S165 that the reliability of the medication report information during the above determination target period is "high".

[0106] It should be noted that the information on medication declaration includes information indicating whether or not a declaration has been made, that is, it includes both declarations of "already taken" and declarations of "not taken". Therefore, the medication declaration reliability determination unit 14 calculates the medication rate (number of declarations of "already taken" / total number of medication declarations (number of declarations of "already taken" + number of declarations of "not taken")), and sets a determination threshold for the degree of dispersion according to the calculated medication rate. That is, the determination threshold is set in such a way that the lower the medication rate, the higher the threshold. By doing this, a more accurate determination can be made.

[0107] That is, if the blood pressure value has a large dispersion when the patient has not actually taken the medicine, but the threshold value has not been adjusted, if the patient has accurately reported "not taking the medicine", the dispersion is large, and therefore the patient will be judged as "low" in terms of reliability even though the patient has accurately reported the medicine. However, as described above, the above-mentioned erroneous judgment can be avoided by adjusting the threshold value.

[0108] (5) Output the results of the reliability of medication reporting

[0109] When the determination of the reliability of the medication report by the above-mentioned medication report reliability determination unit 14 is completed, the user terminal UT starts the determination information output unit 15. Then, under the control of the determination information output unit 15, in step S17, based on the determination result received from the above-mentioned medication report reliability determination unit 14, a notification message is generated for notifying the user himself, the medication manager such as a doctor, a pharmacist, or a family member of the determination result. Then, the notification message for the user himself is output to the input / display device 3 and displayed, and the notification message for the medication manager or the family member is output to the wireless communication circuit 4 and sent from the wireless communication circuit 4 to the medication manager terminal MT or the family member terminal FT. It should be noted that in this case, as a notification message for the user, it can also include "a message to urge the user to report the medication correctly" and "a message to urge the medication itself".

[0110] It should be noted that, in this example, a case is described where only the determination information on the reliability of the medication declaration is sent to the medication manager terminal MT or the family terminal FT. This is based on the premise that the user's medication declaration information is sent to the medication manager terminal MT or the family terminal FT through other processing. On the other hand, when the determination information on the reliability of the medication declaration is sent to the medication manager terminal MT or the family terminal FT, the blood pressure measurement value itself can also be sent together. By doing so, for example, it can be used as a reference for doctors when reviewing changes in prescriptions. In addition, the medication declaration information of users corresponding to the same determination object period can also be sent to the medication manager terminal MT or the family terminal FT. At this time, the medication rate is calculated based on the medication declaration information, and the calculated medication rate is sent to the medication manager terminal MT or the family terminal FT together with the declaration information, or instead of the declaration information.

[0111] As described above, by sending the medication declaration information or medication rate and the judgment result of the reliability of the declaration information together, for example, doctors and pharmacists can consider the reliability of the notified medication declaration when judging the user's medication situation based on the medication declaration information, thereby making a more accurate judgment.

[0112] Furthermore, when notifying the medication rate, the medication rate may be corrected based on the reliability of the medication report (the actual medication rate is predicted). As a correction method, for example, the medication rate based on the reported information may be reduced by a predetermined ratio (for example, to 70% of the reported value).

[0113] Furthermore, the reliability determination process performed by the medication report reliability determination unit 14 may be determined based on whether the dispersion is greater than the threshold value corresponding to the reported medication rate, or may be determined based on the distance from the threshold value corresponding to the reported medication rate, that is, based on the absolute value of the difference regardless of the size. By doing so, even in the case of an erroneous declaration of "not taking" despite the fact that the medication has been taken, it can be determined that the reliability of the declaration is low.

[0114] Furthermore, it is also possible that, for example, if a user forgets to take a medication, they may be bothered to input "not taken" and not report themselves. Therefore, as described above, in the case where there is no report of more than a predetermined ratio, in addition to setting it as "no report", for example, the number of times of no report can be regarded as forgetting to take the medication (i.e., there is a report of "not taken"), and the medication taking rate and the reliability of the report can be calculated.

[0115] Furthermore, in the case where the above-mentioned medication report reliability determination unit 14 determines that "it is necessary to urge the user to make a medication report", the following processing is also considered. That is, the determination information output unit 15 displays a message urging the user to report medication to the user terminal UT. Then, based on the acquisition result of the report information by the medication report information acquisition unit 11, the medication report reliability determination unit 14 determines whether there is a user response to the above-mentioned message urging the medication report, that is, whether the user has input the medication report information. In the case where it is determined that the input operation of the report information has not been performed, it is deemed that there is no report related to medication, and the reliability determination processing of the report information is not performed. If this is done, the reliability determination processing of the report information with defects in the medication report is omitted, thereby reducing the processing load of the user terminal UT.

[0116] (Effect)

[0117] Generally, the dispersion of blood pressure values ​​is related to the compliance of medication. For example, from the dispersion of blood pressure values ​​measured regularly every day during a target period of one week, the dispersion of blood pressure values ​​of patients who comply with medication tends to be small, while the dispersion of blood pressure values ​​of patients who do not comply with medication tends to be large.

[0118] Therefore, in the first embodiment, the medication declaration information acquisition unit 11 receives the user's medication declaration information input, and in parallel, the blood pressure measurement data acquisition unit 12 acquires and stores the user's blood pressure measurement data from the blood pressure monitor BP, and the dispersion degree calculation unit 13 calculates the dispersion degree of the blood pressure values ​​within the determination object period based on the stored blood pressure measurement data, and the medication declaration reliability determination unit 14 determines the reliability of the medication declaration information declared in the same period based on the dispersion degree of the blood pressure measurement values, and the determination information output unit 15 sends the determination result to the medication manager terminal MT, etc.

[0119] Therefore, for example, a doctor, pharmacist or other medication manager can accurately infer the medication status of the user as a patient and judge the effect of the medication. In addition, if the reliability determination result is sent to the terminal FT of a family member, the family member can either directly guide the user himself on the declaration of medication or confirm whether the medication is accurately taken. Moreover, for users who tend to forget to declare medication, by causing the input / display device 3 to display a message urging the declaration of medication, the compliance rate of the user's medication declaration can be improved.

[0120] [Second embodiment]

[0121] A second embodiment of the present invention is to predict future changes in blood pressure based on blood pressure measurement data obtained during a period in the past when medication conditions are known, calculate the deviation between the predicted blood pressure value and the actual measured blood pressure value, and determine the reliability of medication reporting information during the medication period that affects the blood pressure value during the period in which the deviation is calculated.

[0122] For example, a period in which the medication rate is known or the medication rate is corrected based on reliability is selected as a prediction reference period for blood pressure changes (hereinafter referred to as the first period). Then, based on the blood pressure measurement data obtained in the first period, the subsequent blood pressure changes are predicted, and the deviation between the above-mentioned blood pressure prediction value and the actually measured blood pressure value in the period that becomes the monitoring object of the blood pressure value (hereinafter referred to as the second period) is calculated. Then, based on the deviation of the calculated blood pressure value, the reliability of the user's medication declaration information in the medication period (hereinafter referred to as the third period) before the second period that affects the blood pressure value of the second period (that is, the drug effect is manifested) is determined.

[0123] It should be noted that when selecting the first period, if the user has a period in which medication is accurately managed, such as during hospitalization, it is better to select this period as the first period. In addition, if the prescription has a fast-acting drug or the user has a constitution that the drug is easily effective, the third period that is the period for determining the reliability and the second period that is the period for monitoring the deviation may be set to be the same period.

[0124] Furthermore, the first period and the second or third period may not be continuous, but ideally they are discontinuous. This is because it is expected that if the first period and the second or third period are continuous, the degree of change and deviation of the blood pressure value will be too small to be compared.

[0125] In addition, when the first period is continuous with the second or third period, it is desirable that each period has a certain length. This is because the influence of natural blood pressure fluctuations and errors can be reduced. In particular, even if only the actual blood pressure values ​​measured at a certain point are used in the second period, the deviation can be calculated in theory. However, in order to eliminate the influence of natural blood pressure fluctuations and errors, it is desirable to include multiple actual blood pressure values.

[0126] (Configuration example)

[0127] The system using the medication management device of the second embodiment has the same basic configuration as the first embodiment, so its description is omitted. Also, the user terminal UT as the medication management device has the same hardware configuration as described in the first embodiment, so its description is omitted.

[0128] (1) User Terminal UT

[0129] (1-1) Software composition

[0130] Figure 7 It is a block diagram showing the software configuration of the user terminal UT.

[0131] The data storage area of ​​the memory 6 is provided with a medication / blood pressure information storage unit 61 and a prescription information storage unit 62. The medication / blood pressure information storage unit 61 stores input template data used when the user inputs medication declaration information. In addition, in the medication / blood pressure information storage unit 61, the medication declaration information input by the user based on the above-mentioned input template data is associated with the information indicating the date and time of medication and stored. Moreover, in the medication / blood pressure information storage unit 61, the blood pressure measurement data sent from the sphygmomanometer BP is associated with the information indicating the date and time of its measurement and stored. In the prescription information storage unit 62, for example, the prescription information of the target user downloaded from the medication manager terminal MT of a doctor, pharmacist, etc. or the EMR server of a medical institution, etc. is stored.

[0132] The CPU 5, as a processing function unit of the second embodiment, includes a medication report information acquisition unit 51, a blood pressure measurement data acquisition unit 52, a blood pressure change prediction unit 53, a blood pressure comparison unit 54, a medication report reliability determination unit 55, and a determination information output unit 56. These control units 51 to 56 are all realized by causing the CPU 5 to execute an application program stored in the program storage area in the memory 6.

[0133] The medication report information acquisition unit 51 is activated by the input request operation of the medication report by the user, and reads the input template data from the medication / blood pressure information storage unit 61 and displays it on the input / display device 3. Then, the medication report information acquisition unit 51 receives the medication report information input by the user according to the guidance of the input template data from the input / display device 3, and stores the report information in the medication / blood pressure information storage unit 61.

[0134] It should be noted that the medication reporting information includes, for example, information indicating the date and time of medication and information indicating whether medication is taken on that date and time. The information indicating the date and time of medication is indicated by information indicating the medication timing, for example, when the medication is taken after breakfast, after lunch, after dinner, when getting up, when going to bed, etc., as specified by the prescription. In addition, when there are multiple types of medications to be taken, the information indicating whether medication is taken is input according to the type of medication.

[0135] The blood pressure measurement data acquisition unit 52 is activated, for example, by a data transmission request from the blood pressure monitor BP, and performs a process of storing the blood pressure measurement data transmitted from the blood pressure monitor BP and received via the wireless communication circuit 4 together with the information indicating the measurement date and time in the above-mentioned medication / blood pressure information storage unit 61. In addition, at that time, the blood pressure measurement data acquisition unit 52 stores the blood pressure measurement data and the medication reporting information in a state in which the information corresponding to the measurement date and time and the medication date and time are associated with each other.

[0136] The blood pressure change prediction unit 53 first selects a period in which the past medication status is known as a prediction reference period for blood pressure changes (the first period). Then, the blood pressure measurement data obtained in the first period is read from the medication / blood pressure information storage unit 61, and the subsequent changes in blood pressure values ​​are predicted based on the blood pressure measurement data.

[0137] In addition, the blood pressure change prediction unit 53 reads the medication report information in the first period from the medication / blood pressure information storage unit 61, calculates the medication rate based on the medication report information, and reflects the medication rate in the predicted value of the blood pressure value. In other words, the predicted value of the blood pressure value is corrected based on the medication rate in the first period.

[0138] The blood pressure comparison unit 54 sets, for example, a period (second period) that is the monitoring target of the most recent blood pressure value. Then, the blood pressure measurement data (actual blood pressure value) obtained in the second period is read from the medication / blood pressure information storage unit 61, and a process is performed to calculate the deviation of the actual blood pressure value from the predicted blood pressure value in the second period obtained by the blood pressure change prediction unit 53.

[0139] The medication report reliability determination unit 55 performs a process of determining the reliability of medication report information during the medication period (third period) before the blood pressure value in the second period shows the effect of the medicine, based on the deviation of the blood pressure calculated by the blood pressure comparison unit 54. It should be noted that an example of reliability determination is described later.

[0140] The judgment information output unit 56 generates notification information for notifying the medication manager, the user's family or the user himself of the judgment result of the reliability of the medication report information performed by the above-mentioned medication report reliability judgment unit 55, and sends the notification information to the medication manager terminal MT or the family terminal FT or displays it on the input / display device 3.

[0141] (Action Example)

[0142] Next, the operation of the user terminal UT configured as above will be described. Figure 8 and Fig. 9 This is a flowchart showing an example of its operation.

[0143] (1) Obtaining medication reporting information

[0144] The user terminal UT monitors the operation of inputting the medication report information in step S20 in the standby state. In this state, the user clicks, for example, an icon assigned with the medication report function in the input / display device 3. In this way, the user terminal UT starts the medication report information acquisition unit 51. In step S21, the input template data is first read from the medication / blood pressure information storage unit 61 and displayed on the input / display device 3.

[0145] In this state, when the user inputs whether or not to take medicine after breakfast, lunch, or dinner on that day according to the above input template, the input / display device 3 receives information indicating whether or not to take medicine by meal, and stores it in the medicine / blood pressure information storage unit 61. At this time, information indicating the date and time of taking medicine or the date and time when medicine should be taken (hereinafter collectively referred to as the date and time of taking medicine) is added to the information indicating whether or not to take medicine.

[0146] It should be noted that it is also conceivable that the user may summarize and input the declaration of medication for a day, for example, after dinner or before going to bed, or summarize and input it after the second day. In such a case, if the input date and time (declared date and time) is directly used as the medication date and time, the reported medication date and time will be different from the actual medication date and time.

[0147] So, for example, Fig.10 As shown in the example, the input template is provided with check boxes 31a, 32a, 33a for inputting whether or not to take medicine corresponding to the above-mentioned after breakfast, after lunch, and after dinner respectively for the dates and times not inputted, and input fields 31b, 32b, 33b for the time of taking medicine. Then, the information indicating whether or not to take medicine and the information indicating the time of taking medicine inputted in the corresponding check boxes 31a, 32a, 33a and input fields 31b, 32b, 33b for breakfast, lunch, and dinner are stored in the medicine report information storage unit 21 as medicine report information.

[0148] Thereafter, each time the user performs an input request operation for medication report, the user terminal UT receives the above-mentioned medication report information under the control of the medication report information acquisition unit 51 and performs a process of storing the above-mentioned medication report information in the medication report information storage unit 21 .

[0149] (2) Obtaining blood pressure measurement data

[0150] In the standby state, the user terminal UT monitors the request for sending the blood pressure measurement data from the sphygmomanometer BP through step S52. In this state, when receiving the request for sending the blood pressure measurement data from the sphygmomanometer BP, the user terminal UT starts the blood pressure measurement data acquisition unit 52, and in step S23, acquires the blood pressure measurement data sent from the sphygmomanometer BP and received through the wireless communication circuit 4 from the wireless communication circuit 4, and stores the blood pressure measurement data in the medication / blood pressure information storage unit 61. At this time, along with the blood pressure measurement data, information indicating the measurement date and time is sent, so the user terminal UT associates the blood pressure measurement data with the measurement date and time, and associates it with the medication declaration information corresponding to the medication date and time, and stores it in the medication / blood pressure information storage unit 61.

[0151] Thereafter, every time a transmission request is received from the blood pressure monitor BP, the user terminal UT performs the above-mentioned reception / storage processing of the blood pressure measurement data under the control of the blood pressure measurement data acquisition unit 52 .

[0152] (3) Predicting blood pressure changes

[0153] While the user terminal UT performs the above-mentioned acquisition processing of the medication report information and the acquisition processing of the blood pressure measurement data, it monitors the request for determining the reliability of the medication report in step S24. In this state, when receiving a determination request from, for example, the medication manager terminal MT such as a doctor or pharmacist or the family terminal FT, the user terminal UT activates the blood pressure change prediction unit 53.

[0154] Under the control of the blood pressure change prediction unit 53, the user terminal UT, in step S25, for example, first selects a period in which the past medication status is known as a prediction reference period (first period) for blood pressure changes. Then, the medication declaration information and blood pressure measurement data within the first period (for example, one day or one week) are read from the medication / blood pressure information storage unit 61. Then, based on the medication declaration information, for example, the medication rate within the medication period is calculated, and the medication rate is comprehensively considered, and the change in the subsequent blood pressure value is predicted based on the blood pressure measurement data within the medication period. That is, based on the blood pressure value measured in the first period where the medication rate is known, the change in the blood pressure value in the subsequent period is predicted.

[0155] It should be noted that the prediction of the above-mentioned blood pressure value is performed by, for example, obtaining in advance from a database such as an EMR (Electronic Medical Records) server the guideline data indicating the change of the blood pressure value relative to the standard patient's medication dosage and referring to the guideline data, or using a learning model that learns the change of blood pressure based on the user's past medication dosage and blood pressure change history. In addition, for example, when there is a period during which medication has been clearly taken or a period during which the medication rate is clearly correct due to reasons such as hospitalization, this period can also be used as the above-mentioned first period.

[0156] (4) Calculate the deviation of blood pressure

[0157] The user terminal UT then starts the blood pressure comparison unit 54. Under the control of the blood pressure comparison unit 54, in step S26, first, the most recent blood pressure monitoring target period (for example, today) is selected as the second period, and the blood pressure measurement data (actual blood pressure value) in the second period is read from the medication / blood pressure information storage unit 61. Then, the deviation (for example, difference) of the actual blood pressure value from the predicted blood pressure value obtained in the second period among the predicted blood pressure values ​​obtained by the blood pressure change prediction unit 53 is calculated.

[0158] It should be noted that in the calculation of the deviation, the actual blood pressure value at a certain time point in the second period may be compared with the predicted value, or the average of the actual blood pressure values ​​measured at multiple time intervals in the second period may be compared with the predicted value. By doing so, the influence of temporary blood pressure fluctuations can be reduced.

[0159] (5) Determining the reliability of medication reporting

[0160] When the deviation of the blood pressure value in the second period is calculated, the user terminal UT then starts the medication report reliability determination unit 55. Then, under the control of the medication report reliability determination unit 55, in step S27, the medication period (for example, yesterday or today) that affects the blood pressure value in the second period, that is, the medication effect is shown, is taken as the third period, and the medication report information in the third period is read from the medication / blood pressure information storage unit 61. Then, the reliability of the medication report information of the third period read out is determined based on the deviation of the blood pressure in the second period calculated by the blood pressure comparison unit 54.

[0161] Fig. 9 2 is a flowchart showing an example of the order and content of the determination process of the reliability of the medication report. The medication report reliability determination unit 55 first reads the medication report information within the third period from the medication / blood pressure information storage unit 61 in step S271, and determines whether certain medication reports are made based on the medication report information. In other words, it determines whether there are any defects in the medication report.

[0162] For example, when the third period is one day, if there is no medication declaration in the medication declaration time specified by the prescription information stored in the prescription information storage unit 62, even if there is only one medication declaration, it is determined that there is no medication declaration on that day. For example, when the medication declaration time is specified as three times after breakfast, after lunch, and after dinner, and the declaration is that the medication is forgotten after dinner (no medication), it is determined that there is no medication declaration on that day. In addition, for example, when the third period is one week, if the number of days without medication declaration is more than one day or more than a specified number of days, it is determined that there is no medication declaration on that week. Then, when it is determined that there is no medication declaration, the medication declaration reliability determination unit 55 regards the medication declaration information in the third period as outside the determination object of the medication declaration reliability, and in step S272, it is determined that "it is necessary to urge the user to make a medication declaration", and the determination result is transmitted to the determination information output unit 56.

[0163] On the other hand, if it is determined in step S271 that there is a medication report, the medication report reliability determination unit 55 then determines in step S273 whether the deviation of the blood pressure value calculated by the blood pressure comparison unit 54 (the difference between the predicted value and the measured value of the blood pressure) is greater than the threshold value. As a result of this determination, if the deviation of the blood pressure value is greater than the threshold value, the medication report reliability determination unit 55 determines in step S274 that the reliability of the medication report information within the third period is "low". On the other hand, if the deviation of the blood pressure value is less than the threshold value, the medication report reliability determination unit 55 determines in step S275 that the reliability of the medication report information within the third period is "high".

[0164] (6) Output the results of the reliability of medication reporting

[0165] When the determination process of the reliability of the medication report by the above-mentioned medication report reliability determination unit 55 is completed, the user terminal UT starts the determination information output unit 56. Then, under the control of the determination information output unit 56, in step S28, based on the determination result received from the above-mentioned medication report reliability determination unit 55, a notification message for notifying the user himself, a medication manager such as a doctor or a pharmacist, or a family member of the determination result is generated. Then, the notification message for the user himself is output to the input / display device 3 and displayed, and the notification message for the medication manager or the family member is output to the wireless communication circuit 4 and sent from the wireless communication circuit 4 to the medication manager terminal MT or the family member terminal FT.

[0166] It should be noted that in this example, the case where only the determination information of the reliability of the medication declaration is sent to the medication manager terminal MT or the family terminal FT is described. This is based on the premise that the user's medication declaration information is sent to the medication manager terminal MT or the family terminal FT through other processing. On the other hand, when the determination information of the reliability of the medication declaration is sent to the medication manager terminal MT or the family terminal FT, the medication declaration information of the user corresponding to the same medication period (third period) can also be sent to the medication manager terminal MT or the family terminal FT. At this time, the medication rate is calculated based on the declaration information, and the calculated medication rate is sent to the medication manager terminal MT or the family terminal FT together with the declaration information, or instead of the declaration information.

[0167] As described above, by sending the medication declaration information or medication rate and the judgment result of the reliability of the declaration information together, for example, a doctor or pharmacist can consider the reliability of the notified medication declaration when judging the user's medication situation based on the medication declaration information, thereby making a more accurate judgment.

[0168] Furthermore, when notifying the medication rate, the medication rate may be corrected based on the reliability of the medication report (the actual medication rate is predicted). As a correction method, for example, the medication rate based on the reported information may be reduced by a predetermined ratio (for example, to 70% of the reported value).

[0169] Furthermore, the reliability determination process performed by the medication report reliability determination unit 55 may be determined based on whether the deviation of the blood pressure is greater than the threshold value corresponding to the reported medication rate, or may be determined based on the distance from the threshold value corresponding to the reported medication rate, that is, based on the absolute value of the difference regardless of the size. In this way, even when an erroneous declaration of "not taking the medication" is made despite the fact that the medication has been taken, it can be determined that the reliability of the declaration is low.

[0170] Furthermore, it is also possible that, for example, if a user forgets to take a medication, they may be bothered to input "not taken" and not report themselves. Therefore, as described above, in the case where there is no report of more than a predetermined ratio, in addition to setting it as "no report", for example, the number of times of no report can be regarded as forgetting to take the medication (i.e., there is a report of "not taken"), and the medication taking rate and the reliability of the report can be calculated.

[0171] Furthermore, in the case where the above-mentioned medication report reliability determination unit 14 determines that "it is necessary to urge the user to make a medication report", the following processing is also considered. That is, the determination information output unit 15 displays a message urging the user to report medication to the user terminal UT. Then, based on the acquisition result of the report information by the medication report information acquisition unit 11, the medication report reliability determination unit 14 determines whether there is a user response to the above-mentioned message urging the medication report, that is, whether the user has input the medication report information. In the case where it is determined that the input operation of the report information has not been performed, it is deemed that there is no report related to medication, and the reliability determination processing of the report information is not performed. If this is done, the reliability determination processing of the report information with defects in the medication report is omitted, thereby reducing the processing load of the user terminal UT.

[0172] (Effect)

[0173] In general, considering that the difference between the predicted value and the actual value of the blood pressure of a user who complies with medication is small, there is a tendency that the deviation between the predicted value of the blood pressure in the most recent blood pressure monitoring period (second period) predicted from the blood pressure value measured in the past prediction reference period (first period) with a known medication rate and the actual value of the blood pressure value actually measured in the second period is small. On the other hand, if a user who does not comply with medication has declared taking medication as if complying with medication, it is estimated that the deviation between the predicted value of the blood pressure in the second period when the drug effect should be manifested and the actual value of the blood pressure actually measured is large.

[0174] Therefore, in the second embodiment, the blood pressure change prediction unit 53 predicts the change of blood pressure in the most recent blood pressure monitoring period (the second period) based on the blood pressure measurement data measured in the prediction reference period (the first period) in which the medication rate is known in the past, and the blood pressure comparison unit 54 calculates the deviation between the predicted value of the blood pressure and the actual value of the blood pressure actually measured in the second period. Then, based on the calculated blood pressure deviation, the medication report reliability determination unit 55 determines the reliability of the medication report information in the medication period (the third period) before the blood pressure value in the second period is affected (the drug effect is manifested), and the information indicating the determination result is output to the medication manager terminal MT, etc. by the determination information output unit 56.

[0175] Therefore, for example, a doctor, pharmacist or other medication manager can more accurately infer the medication situation during the medication period before the blood pressure during the most recent blood pressure monitoring period of the user as a patient (the drug effect is manifested), and judge the effect of the medication. In addition, if the determination result of the reliability of the medication declaration is sent to the terminal FT of a family member, the family member can either directly guide the user himself on the medication declaration, or can confirm whether the medication is taken accurately. Moreover, for users who easily forget to declare medication, by causing the input / display device 3 to display a message urging the declaration of medication, the compliance rate of the medication declaration made by the user can be improved.

[0176] [Modifications]

[0177] (1) The reliability of the medication report determined during the period of the object of determination of the reliability of the medication report, that is, the object period of the first embodiment or the third period of the second embodiment, can also be regarded as being temporarily continued until the reliability of the medication report is determined next time, that is, after the object period or the third period, until the entire period including the second period of the second embodiment is maintained. This can be achieved by storing the reliability of the medication report determined by the medication report reliability determination unit 14 or 55 in the above-mentioned object period or the third period in advance in the reliability storage unit (not shown) in the memory 2 until the reliability determination process is next performed in the medication report reliability determination unit 14 or 55, and updating it every time a new reliability is obtained.

[0178] (2) In the first and second embodiments, the case where the medication management function of the present invention is set in the user terminal UT is described as an example. However, the present invention is not limited to this. For example, the medication management function of the present invention may be set in a server device operated by a medical institution such as a hospital or a pharmacy, or may be set in a server device operated by a service operator related to medical care, medicine, or nursing.

[0179] Like this, in the case where the server device is provided with a function for managing medication status, for example, medication declaration information input by the user in the user terminal and biological information measured by the sphygmomanometer are sent from the user terminal to the server device at regular intervals, and the server device receives and stores the medication declaration information and biological information sent from the above-mentioned user terminal, and executes a series of processes described in the first and second embodiments according to a preset judgment timing or the input of a judgment request from a doctor, etc., thereby enabling implementation.

[0180] (3) In the first and second embodiments, the function of the medication status management device is provided in a portable information terminal (user terminal) such as a smart phone owned by the user. However, for example, the function of the medication status management device may also be provided in a wearable terminal with a blood pressure measurement function.

[0181] (4) In the first and second embodiments, the reliability of the medication report information is determined by comparing the dispersion of the blood pressure values ​​or the deviation of the actual blood pressure values ​​from the predicted values ​​with a threshold value. However, this is not limited to this. For example, multiple threshold values ​​may be set, and the reliability of the medication report information may be determined in multiple stages by comparing the dispersion of the blood pressure values ​​or the deviation of the actual blood pressure values ​​from the predicted values ​​with the multiple threshold values.

[0182] (5) In the first and second embodiments, the case of obtaining blood pressure measurement data as biological information is described as an example. However, measurement data of blood sugar level, uric acid level, creatinine level, cholesterol level, blood oxygen saturation concentration (SPO2), as well as measurement data of weight, waist circumference, body fat percentage, etc. may also be obtained, and the degree of dispersion or the degree of deviation from the predicted value may be calculated, and the reliability of the medication report information may be determined based on the result.

[0183] (6) In addition, various modifications may be made to the composition of the medication status management device, the processing order and content, the composition of the information indicating the result of the determination of the reliability of the medication report information, the notification destination, the selection method of the first, second and third periods described in the second embodiment and their lengths, etc., without departing from the main purpose of the present invention.

[0184] Above, multiple embodiments and variations of the present invention have been described in detail, but the descriptions so far are only examples of the present invention in all aspects, and various improvements and variations can certainly be made without departing from the scope of the present invention. In other words, when implementing the present invention, specific structures corresponding to each embodiment can also be appropriately adopted.

[0185] In addition, for the present invention, various inventions can be formed by appropriate combinations of multiple constituent elements disclosed in the above-mentioned embodiments. For example, some constituent elements can be deleted from all constituent elements shown in each embodiment. In addition, the constituent elements in different embodiments can be appropriately combined.

[0186] [Note]

[0187] A part or all of each of the above-mentioned embodiments may be described as shown in the following supplementary notes in addition to the claims, but the present invention is not limited thereto.

[0188] (Note 1)

[0189] A medication status management device comprises a hardware processor and a storage medium, wherein:

[0190] The hardware processor is configured to perform the following processing:

[0191] Processing of obtaining declaration information related to the user's medication;

[0192] Acquiring the biometric information of the user and storing it in the storage medium;

[0193] a process of calculating a dispersion degree of the biometric information acquired during a target period based on the biometric information stored in the storage medium;

[0194] A process of determining the reliability of the reported information related to medication acquired during the subject period based on the dispersion degree of the biological information; and

[0195] A process of outputting information indicating the result of the reliability determination is performed.

[0196] (Note 2)

[0197] A medication status management device comprises a hardware processor and a storage medium, wherein:

[0198] The hardware processor is configured to perform the following processing:

[0199] Acquiring declaration information related to the user's medication and storing it in the storage medium;

[0200] A process of acquiring biometric information of the user and storing the biometric information in the storage medium in a state in which the reported information and information corresponding to the acquisition timing thereof can be associated with each other;

[0201] Processing for calculating a predicted value of the biological information in a second period to be monitored by the biological information based on the reported information and biological information in a first period in which the medication status is known and stored in the storage medium;

[0202] a process of calculating a degree of deviation of the actual value of the biometric information acquired during the second period from the calculated predicted value of the biometric information;

[0203] A process of determining the reliability of the reported information on medication in a third period before the second period that affects the change of the biological information in the second period based on the calculated deviation degree; and

[0204] A process of outputting information indicating the result of the reliability determination is performed.

[0205] Description of Reference Numerals

[0206] UT…Portable Information Terminal

[0207] BP…Blood Pressure Monitor

[0208] NW…Network

[0209] MT…Manager Terminal

[0210] FT…Family Terminal

[0211] 1.5…CPU

[0212] 2.6…Memory

[0213] 3. 100… Input / display device

[0214] 4. 700… Wireless communication circuit

[0215] 11, 51, 400…Medication reporting information acquisition department

[0216] 12, 52, 200…Blood pressure measurement data acquisition unit

[0217] 13. 300…Dispersion degree calculation unit

[0218] 14, 55, 500…Department of reliability assessment of medication reports

[0219] 15, 56, 600...Judgment information output unit

[0220] 21…Medication reporting information storage department

[0221] 22…Blood pressure measurement data storage unit

[0222] 41…Antenna

[0223] 53…Blood Pressure Change Prediction Department

[0224] 54…Blood Pressure Comparison

[0225] 61…Medication / blood pressure information storage unit

Claims

1. A medication management device, comprising: a declared information acquisition unit, the declared information acquisition unit acquiring declared information related to the user's medication, the declared information being information on the medication status of the user during the medication declaration period; a biometric information acquisition unit, which acquires the biometric information of the user and stores it in a storage medium; a calculation unit that calculates a dispersion degree of the biometric information acquired during a target period based on the biometric information stored in the storage medium; a reliability determination unit that determines the reliability of the reported information related to medication acquired during the target period based on the dispersion degree of the biological information; and an output unit for outputting information indicating a result of the reliability determination, The reliability determination unit determines whether the dispersion degree of the biological information calculated by the calculation unit is higher or lower than a threshold value. When the reliability determination unit determines that the dispersion degree of the biological information is higher than a threshold value, the output unit generates a message urging correct taking of the medication or reporting of the medication, and outputs the message to at least one of the terminal of the user and the terminal of a person having a prescribed relationship with the user.

2. A medication management device, comprising: a declaration information acquisition unit, the declaration information acquisition unit acquiring declaration information related to the user's medication and storing it in a storage medium, the declaration information being information on the user's medication status during the medication period declared; a biometric information acquisition unit that acquires biometric information of the user and stores the biometric information in the storage medium in a state in which the declared information and information corresponding to the acquisition timing thereof can be associated with each other; a prediction unit that calculates a predicted value of the biological information in a second period that is a monitoring target of the biological information based on the reported information and the biological information in a first period in which the medication status is known and stored in the storage medium; a calculation unit that calculates a degree of deviation of the measured value of the biometric information acquired during the second period from the calculated predicted value of the biometric information; a reliability determination unit that determines the reliability of the reported information related to medication in a third period before the second period that affects the change of the biological information in the second period based on the calculated deviation degree; and An output unit outputs information indicating a result of the reliability determination.

3. The medication status management device according to claim 1, wherein: The reliability determination unit Based on the reported information on medication, a medication taking rate indicating the ratio of the number of times the medication has been reported to have been taken to the total number of reported medications taken during the reporting period for the medication, is calculated; The threshold value is set based on the calculated medication taking rate so that the lower the medication taking rate is, the higher the value is.

4. The medication status management device according to claim 1 or 2, wherein: The reliability determination unit Based on the reported information related to medication, determining whether there is any missing information related to medication in the reported information, If it is determined that the report is missing, it is determined that it is necessary to urge the user to make a report related to medication.

5. The medication status management device according to claim 4, wherein: The output unit outputs information urging the user to make a report on taking medication when the reliability determination unit determines that it is necessary to urge the user to make a report on taking medication, The reliability determination unit determines whether the user has responded to the prompt urging the user to make a declaration of information related to medication. If it is determined that the user has not responded, it is deemed that the declaration related to medication has not been made, and the reliability determination process for the declaration information is omitted.

6. The medication status management device according to claim 1 or 2, further comprising: a medication taking rate calculation unit that calculates a medication taking rate indicating a ratio of the number of times the medication has been reported to have been taken to the total number of times the medication has been reported within a reporting target period for the medication taking, based on the reported information on the medication taking; and The correction unit corrects the medication rate based on a result of the reliability determination of the reported information by the reliability determination unit.

7. The medication status management device according to claim 1 or 2, wherein: The output unit transmits information indicating a result of the reliability determination to a terminal used by a medication manager for the user.

8. The medication status management device according to claim 1 or 2, wherein: The reliability determination unit stores the reliability determination result in the storage medium, and updates the reliability determination result stored in the storage medium every time a new reliability determination result is obtained.

9. A method for managing medication status, The method is executed by an information processing device having a processor and a storage medium, and comprises: The information processing device acquires the reported information related to the medication of the user and stores it in the storage medium, wherein the reported information is information about the medication status of the user during the medication reporting period; The information processing device acquires the biological information of the user and stores it in the storage medium; a process of calculating the dispersion degree of the biometric information acquired during the object period based on the biometric information stored in the storage medium; A process of determining the reliability of the reported information related to medication acquired during the subject period based on the calculated dispersion of the biological information; as well as The process of outputting information indicating the result of the reliability determination, The reliability determination process determines whether the dispersion degree of the biological information calculated by the calculation process is higher or lower than a threshold value. The output process generates a message urging correct taking of the medication or reporting of the medication when the process for determining the reliability determines that the dispersion of the biological information is higher than a threshold value, and outputs the message to at least one of the terminal of the user and the terminal of a person having a prescribed relationship with the user.

10. A method for managing medication status, The method is executed by an information processing device having a processor and a storage medium, and comprises: The information processing device acquires the reported information related to the medication of the user and stores it in the storage medium, wherein the reported information is information about the medication status of the user during the medication reporting period; The information processing device acquires the biological information of the user and stores it in the storage medium; The information processing device calculates a predicted value of the biological information in a second period to be monitored by the biological information based on the reported information and biological information in a first period in which the medication status is known and stored in the storage medium; The information processing device calculates a degree of deviation of the measured value of the biometric information acquired during the second period from the calculated predicted value of the biometric information; The information processing device determines the reliability of the reported information related to medication in a third period before the second period that affects the change of the biological information in the second period based on the calculated deviation degree; as well as A process in which the information processing device outputs information indicating a result of the reliability determination.

11. A computer-readable recording medium having a program recorded thereon, The program causes a processor included in the medication schedule management device to execute processing performed by the respective units included in the medication schedule management device according to any one of claims 1 , 3 , 4 , 5 , 6 , 7 , and 8 .

12. A computer-readable recording medium having a program recorded thereon, The program causes a processor included in the medication schedule management device to execute processing performed by the respective units included in the medication schedule management device according to any one of claims 2, 3, 4, 5, 6, 7, and 8.

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