Methods for selective oxidation of carotenoids by catalyst

Abstract

The invention discloses a method for catalyzing the selective oxidation of carotenoids, comprising: placing a carotenoid compound in a reaction container; adding a solvent and a solid oxidation catalyst in the reaction container, wherein the solid oxidation catalyst is a catalyst with active components loaded on a carrier; charging an oxygen-containing gas into the reaction container; heating the reaction container and stirring for a preset time to cause a selective oxidation reaction to generate a target product. The method for catalyzing the selective oxidation of carotenoids of the invention realizes efficient selective oxidation of carotenoids under the action of a solid oxidation catalyst, and realizes selective cleavage of carbon-carbon bonds at different positions in carotenoid compound molecules by regulating the catalytic system; the conversion rate of carotenoids and the selectivity of the target product are high; the process is simple, and after the catalytic selective oxidation reaction is completed, the target product can be obtained by simple separation; the solid catalyst is easy to separate from the reaction system, and the activity is not significantly reduced after repeated use.

Description

Technical Field

[0001] The invention relates to the technical field of carotenoid selective oxidation production, in particular to a method for catalyzing carotenoid selective oxidation. Background Art

[0002] Carotenoid compounds can be oxidized to produce a variety of important oxidation products, such as β-carotene can be oxidized to β-cyclolimonene, dihydroactin, β-ionone, β-dihydrodamascone, etc.; α-carotene can be oxidized to α-ionone and β-ionone, etc.; lutein can be oxidized to megastigmatriene, oxidized isophorone, β-damascone, etc.; neolutein can be oxidized to grasshopper ketone, etc.; hexahydrophytoene and phytoene can be oxidized to 6-methyl-5-heptene-2-one, isooctadienone (alcohol), etc. The above oxidation products can generally be used as important, high-value-added spices and chemical and pharmaceutical intermediates.

[0003] However, since carotenoid compounds are tetraterpenoid compounds composed of isoprene structural units, there are a large number of relatively active conjugated carbon-carbon double bonds in the molecule. Therefore, when the oxidation reaction occurs directly, the carbon-carbon double bonds at different positions can be broken, so a mixture of the above oxidation products is often obtained, and the product selectivity is difficult to accurately control. Therefore, it is an important research direction to develop an efficient catalytic oxidation system to achieve the selective oxidation of carotenoids and improve the selectivity of oxidation products.

[0004] Therefore, a method for catalyzing the selective oxidation of carotenoids is urgently needed. Summary of the invention

[0005] The purpose of the present invention is to provide a method for catalyzing the selective oxidation of carotenoids to solve the above-mentioned problems in the prior art. Under the action of an efficient solid oxidation catalyst, carotenoid compounds can undergo a selective oxidation reaction to achieve highly selective synthesis of the target product.

[0006] The present invention provides a method for catalyzing the selective oxidation of carotenoids, which comprises:

[0007] placing a carotenoid compound in a reaction vessel;

[0008] Adding a preset solvent and a solid oxidation catalyst into the reaction container, wherein the solid oxidation catalyst is a catalyst with active components loaded on a carrier;

[0009] Filling the reaction vessel with oxygen-containing gas;

[0010] The reaction container is heated and stirred for a preset time to allow the carotenoid compound to undergo a selective oxidation reaction to generate a target product.

[0011] The method for catalyzing the selective oxidation of carotenoids as described above, wherein, preferably, the carotenoid compound is one or more of α-carotene, β-carotene, γ-carotene, lycopene, phytoene, phytoene, lutein, zeaxanthin, cryptoxanthin, neoxanthin and violaxanthin.

[0012] In the method for catalyzing the selective oxidation of carotenoids as described above, preferably, the solvent is one or more of water, methanol, ethanol, glycerol, 1,3-propylene glycol, 1,2-propylene glycol, ethyl acetate, petroleum ether, acetone, ether and chloroform.

[0013] The method for catalyzing the selective oxidation of carotenoids as described above, wherein preferably, the mass ratio of the carotenoid compound to the solvent is 1:3-10 4 .

[0014] The method for catalyzing the selective oxidation of carotenoids as described above, wherein, preferably, the carrier of the solid oxidation catalyst is one or more of activated carbon, Amberlyst 15, ZSM-5 molecular sieve, HZSM-5 molecular sieve, ZSM-11 molecular sieve, HY molecular sieve, Hβ molecular sieve and mordenite.

[0015] The method for catalyzing the selective oxidation of carotenoids as described above, wherein, preferably, the active component of the solid oxidation catalyst is one or more of Fe2O3, Co3O4, MnO2, Mn3O4, Ni2O3, CuO, Nb2O5, MoO3, RuO2, Rh2O3, AuO, ReO3, V2O5, VO2, V2O3, Cr2O3.

[0016] The method for catalyzing the selective oxidation of carotenoids as described above, wherein preferably, the mass ratio of the carrier to the active component of the solid oxidation catalyst is 1:10 -5 -10 -1 .

[0017] The method for catalyzing the selective oxidation of carotenoids as described above, wherein, preferably, the target product corresponding to the carotenoid compound is one or more of 2,2,6-trimethyl-5-cyclohexenone, β-cyclocitral, dihydroactinol, α-ionone, β-ionone, β-dihydrodamascone, 3-hydroxy-α-ionone, 3-oxidized-α-ionol, megastigmatrienone, oxidized isophorone, 3-hydroxy-β-ionone, β-damascone, grasshopper ketone, 6-methyl-5-heptene-2-one, 6-methyl-2-heptenone, isooctadienone and isooctadienol.

[0018] The method for catalyzing the selective oxidation of carotenoids as described above, wherein, preferably, the mass ratio of the solid oxidation catalyst to the carotenoid compound is 10 based on the active component. -6 -10 -2 :1, the partial pressure of oxygen in the oxygen-containing gas filled into the reaction vessel is 0.01-10.0 MPa, the oxidation reaction temperature is 0-200°C, the stirring speed is 20-1000rpm, and the reaction time is 0.1-72h.

[0019] The invention provides a method for catalyzing the selective oxidation of carotenoids. Under the action of an efficient solid oxidation catalyst, a carotenoid compound undergoes a selective oxidation reaction to achieve highly selective synthesis of a target product. The method realizes highly efficient selective oxidation of carotenoids for the first time, and selective cleavage of carbon-carbon bonds at different positions in carotenoid compound molecules is achieved by regulating the catalytic system. The carotenoid conversion rate and the target product selectivity are high, and the carotenoid conversion rate can reach up to more than 99%, and the target product selectivity can reach up to more than 98%. The process is simple, and after the catalytic selective oxidation reaction is completed, the target product can be obtained by simple separation. The solid catalyst is easy to separate from the reaction system, and after being repeatedly used three times, the activity is not significantly reduced. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] In order to make the purpose, technical solutions and advantages of the present invention more clear, the present invention will be further described below with reference to the accompanying drawings, in which:

[0021] Figure 1 A flow chart of an embodiment of a method for catalyzing selective oxidation of carotenoids provided by the present invention;

[0022] Figure 2 This is a schematic diagram of the catalytic performance of the catalyst of Example 11 after repeated use. DETAILED DESCRIPTION

[0023] Various exemplary embodiments of the present disclosure will now be described in detail with reference to the accompanying drawings. The description of the exemplary embodiments is merely illustrative and is in no way intended to limit the present disclosure and its application or use. The present disclosure can be implemented in many different forms and is not limited to the embodiments described herein. These embodiments are provided to make the present disclosure thorough and complete and to fully express the scope of the present disclosure to those skilled in the art. It should be noted that unless otherwise specifically stated, the relative arrangement of the components and steps, the composition of the materials, the numerical expressions and the numerical values ​​set forth in these embodiments should be interpreted as being merely exemplary and not as limiting.

[0024] The words "first", "second" and similar words used in this disclosure do not indicate any order, quantity or importance, but are only used to distinguish different parts. The words "include" or "comprises" and similar words mean that the elements before the word include the elements listed after the word, and do not exclude the possibility of including other elements. "Up", "down" and the like are only used to indicate relative positional relationships. When the absolute position of the described object changes, the relative positional relationship may also change accordingly.

[0025] In the present disclosure, when a specific component is described as being located between a first component and a second component, there may or may not be an intermediate component between the specific component and the first component or the second component. When a specific component is described as being connected to other components, the specific component may be directly connected to the other components without an intermediate component, or may not be directly connected to the other components but have an intermediate component.

[0026] All terms (including technical terms or scientific terms) used in the present disclosure have the same meanings as those understood by ordinary technicians in the field to which the present disclosure belongs, unless otherwise specifically defined. It should also be understood that terms defined in general dictionaries, such as general dictionaries, should be interpreted as having meanings consistent with their meanings in the context of the relevant technology, and should not be interpreted in an idealized or extremely formal sense, unless explicitly defined herein.

[0027] Technologies, methods, and equipment known to ordinary technicians in the relevant art may not be discussed in detail, but where appropriate, the technologies, methods, and equipment should be considered part of the specification.

[0028] Example 1

[0029] like Figure 1 As shown, the method for catalyzing the selective oxidation of carotenoids provided in this embodiment comprises the following steps in actual implementation:

[0030] Step S1, placing a carotenoid compound in a reaction container.

[0031] The reaction container may be, for example, a stainless steel reactor.

[0032] The carotenoid compound is one or more of α-carotene, β-carotene, γ-carotene, lycopene, phytoene, phytoene, lutein, zeaxanthin, cryptoxanthin, neoxanthin and violaxanthin.

[0033] Step S2: adding a preset solvent and a solid oxidation catalyst into the reaction container, wherein the solid oxidation catalyst is a catalyst with active components loaded on a carrier.

[0034] Wherein, based on the active component, the mass ratio of the solid oxidation catalyst to the carotenoid compound is 10 -6 -10 -2 :1, it should be noted that the present invention does not specifically limit the ratio of the solid oxidation catalyst to the carotenoid compound.

[0035] Specifically, the carrier of the solid oxidation catalyst is one or more of activated carbon, Amberlyst 15, ZSM-5 molecular sieve, HZSM-5 molecular sieve, ZSM-11 molecular sieve, HY molecular sieve, Hβ molecular sieve and mordenite. The active component of the solid oxidation catalyst is one or more of Fe2O3, Co3O4, MnO2, Mn3O4, Ni2O3, CuO, Nb2O5, MoO3, RuO2, Rh2O3, AuO, ReO3, V2O5, VO2, V2O3, Cr2O3. The mass ratio of the carrier of the solid oxidation catalyst to the active component is 1:10 -5 -10 -1 It should be noted that the present invention does not specifically limit the carrier, active component, and the ratio of the carrier and active component of the solid oxidation catalyst.

[0036] Furthermore, the solvent is one or more of water, methanol, ethanol, glycerol, 1,3-propylene glycol, 1,2-propylene glycol, ethyl acetate, petroleum ether, acetone, ether and chloroform. The mass ratio of the carotenoid compound to the solvent is 1:3-10 4 It should be noted that the present invention does not specifically limit the solvent and the ratio of the carotenoid compound to the solvent.

[0037] Step S3, charging the reaction container with oxygen-containing gas.

[0038] The partial pressure of oxygen in the oxygen-containing gas charged into the reaction container is 0.01-10.0 MPa. It should be noted that the partial pressure of oxygen in the oxygen-containing gas and the oxidation reaction temperature are not specifically limited in the present invention.

[0039] Step S4, heating the reaction container and stirring for a preset time to allow the carotenoid compound to undergo a selective oxidation reaction to generate a target product.

[0040] Wherein, the oxidation reaction temperature is 0-200 ℃, the stirring speed is 20-1000rpm, and the reaction time is 0.1-72h. It should be noted that the present invention does not specifically limit the reaction conditions (such as oxidation reaction temperature, stirring speed and reaction time, etc.). After the catalytic selective oxidation reaction is completed, the target product can be obtained by simple separation, for example, by a combination of extraction, recrystallization and column chromatography separation. Since the selectivity of the product is high and the impurities are relatively small, a product with higher purity can be obtained by simple extraction and recrystallization process.

[0041] Furthermore, the target product corresponding to the carotenoid compound is one or more of 2,2,6-trimethyl-5-cyclohexenone, β-cyclocitral, dihydroactin, α-ionone, β-ionone, β-dihydrodamascone, 3-hydroxy-α-ionone, 3-oxidized-α-ionol, megastigmatrienone, oxidized isophorone, 3-hydroxy-β-ionone, β-damascone, grasshopper ketone, 6-methyl-5-heptene-2-one, 6-methyl-2-heptenone, isooctadienone and isooctadienol.

[0042] Specifically, β-carotene can be oxidized to produce β-cyclolimonene, dihydroactin, β-ionone, β-dihydrodamascone, etc.; α-carotene can be oxidized to produce α-ionone and β-ionone, etc.; lutein can be oxidized to produce megastigmatrienone, oxidized isophorone, β-damascone, etc.; neolutein can be oxidized to produce grasshopper ketone, etc.; hexahydrophytoene and phytoene can be oxidized to produce 6-methyl-5-heptene-2-one, isooctadienone (alcohol), etc.

[0043] It can be understood by those skilled in the art that there is no corresponding relationship between the carotenoid compound as a reactant and the carrier and active component of the solid oxidation catalyst. Different reactants can use different catalyst active components and carriers to obtain different target products. As described in Examples 2, 7, 11 and Examples 3, 5, 10 to be described later, β-carotene and lutein are catalyzed using different catalysts, and the main target products obtained are different.

[0044] Example 2

[0045] Take 0.1g β-carotene, put it into a 10ml stainless steel reactor, add 2.0mg Nb2O5 / activated carbon catalyst (the mass ratio of the carrier to the active component is 1:10 -1), add 2.0g water to the kettle. After sealing the kettle and replacing the gas in the kettle with oxygen for 3 times, fill the kettle with oxygen until the pressure in the kettle is 1.0MPa, turn on the mechanical stirring, the speed is 300rpm, control the temperature in the reactor to 25°C and start the reaction, keep the gas pressure in the kettle at 1.0MPa, and the reaction time is 12h. After the reaction is completed, add a certain amount of n-heptadecane internal standard and dichloromethane, take a certain amount of sample after drying with anhydrous sodium sulfate, and perform high performance liquid chromatography and gas chromatography analysis, both using internal standard method for quantification. The conversion rate of β-carotene is 100%, 2,2,6-trimethyl-5-cyclohexenone is the main product, and its selectivity is 90.3%.

[0046] Example 3

[0047] Take 0.1g lutein, put it into a 10ml stainless steel reactor, add 3.0mg V2O3 / ZSM-11 catalyst (the mass ratio of the carrier to the active component is 1:10 -1 ), add 1.0g methanol to the kettle. After sealing the kettle and replacing the gas in the kettle with oxygen 3 times, fill the kettle with oxygen until the pressure in the kettle is 1.5MPa, turn on the mechanical stirring, the speed is 400rpm, control the temperature in the reactor to 25°C and start the reaction, keep the gas pressure in the kettle at 1.5MPa unchanged, and the reaction time is 18h. After the reaction is completed, add a certain amount of n-heptadecane internal standard and dichloromethane, take a certain amount of sample after drying with anhydrous sodium sulfate, perform high performance liquid chromatography and gas chromatography analysis, and both use internal standard method for quantification. The conversion rate of lutein is 100%, and megastigmatrienone is the main product with a selectivity of 95.7%.

[0048] Example 4

[0049] Take 0.1g of phytoene and put it into a 10ml stainless steel reactor, add 10.0mg Co3O4 / ZSM-5 catalyst (the mass ratio of the carrier to the active component is 1:10 -1 ), add 2.0g ethanol to the kettle. After sealing the kettle and replacing the gas in the kettle with oxygen for 3 times, fill the kettle with oxygen until the pressure in the kettle is 1.0MPa, turn on the mechanical stirring, the speed is 450rpm, control the temperature in the reactor to 30°C and start the reaction, keep the gas pressure in the kettle at 1.0MPa, and the reaction time is 15h. After the reaction is completed, add a certain amount of n-heptadecane internal standard and dichloromethane, take a certain amount of sample after drying with anhydrous sodium sulfate, and perform high performance liquid chromatography and gas chromatography analysis, both using internal standard method for quantification. The conversion rate of hexahydrophytoopene is 100%, 6-methyl-2-heptanone is the main product, and its selectivity is 86.1%.

[0050] Example 5

[0051] Take 0.1g lutein, put it into a 10ml stainless steel reactor, add 20.0mg MnO2 / HY catalyst (the mass ratio of the carrier to the active component is 1:10 -1 ), add 5.0g 1,2-propylene glycol to the kettle. After sealing the kettle and replacing the gas in the kettle with oxygen for 3 times, fill the kettle with oxygen until the pressure in the kettle is 0.5MPa, turn on the mechanical stirring, the speed is 300rpm, control the temperature in the reactor to 40℃ and start the reaction, keep the gas pressure in the kettle constant at 0.5MPa, and the reaction time is 6h. After the reaction is completed, add a certain amount of n-heptadecane internal standard and dichloromethane, take a certain amount of sample after drying with anhydrous sodium sulfate, and perform high performance liquid chromatography and gas chromatography analysis, both of which are quantitatively analyzed by internal standard method. The conversion rate of lutein is 100%, and oxidized isophorone is the main product, with a selectivity of 91.3%.

[0052] Example 6

[0053] Take 0.1g α-carotene, put it into a 20ml stainless steel reactor, add 30.0mg MoO3 / Hβ catalyst (the mass ratio of the carrier to the active component is 1:10 -1 ), add 10.0g ethanol to the kettle. After sealing the kettle and replacing the gas in the kettle with oxygen for 3 times, fill the kettle with oxygen until the pressure in the kettle is 0.3MPa, turn on the mechanical stirring, the speed is 200rpm, control the temperature in the reactor to 50℃ and start the reaction, keep the gas pressure in the kettle at 0.3MPa, and the reaction time is 3h. After the reaction is completed, add a certain amount of n-heptadecane internal standard and dichloromethane, take a certain amount of sample after drying with anhydrous sodium sulfate, and perform high performance liquid chromatography and gas chromatography analysis, both using internal standard method for quantification. The conversion rate of α-carotene is 100%, α-ionone is the main product, and its selectivity is 92.7%.

[0054] Example 7

[0055] Take 0.1g β-carotene, put it into a 100ml stainless steel reactor, add 10.0mg Cr2O3 / HZSM-5 catalyst (the mass ratio of the carrier to the active component is 1:10 -1 ), add 30.0g glycerol to the kettle. After sealing the kettle and replacing the gas in the kettle with oxygen for 3 times, fill the kettle with oxygen until the pressure in the kettle is 0.3MPa, turn on the mechanical stirring, the speed is 700rpm, control the temperature in the reactor to 30°C and start the reaction, keep the gas pressure in the kettle constant at 0.3MPa, and the reaction time is 1h. After the reaction is completed, add a certain amount of n-heptadecane internal standard and dichloromethane, take a certain amount of sample after drying with anhydrous sodium sulfate, and perform high performance liquid chromatography and gas chromatography analysis, both using internal standard method for quantification. The conversion rate of β-carotene is 100%, β-ionone is the main product, and its selectivity is 91.6%.

[0056] Example 8

[0057] Take 0.5g of new lutein, put it into a 100ml stainless steel reactor, add 5.0mg Ni2O3 / activated carbon catalyst (the mass ratio of the carrier to the active component is 1:10 -1 ), add 50.0g ethyl acetate to the kettle. After sealing the kettle and replacing the gas in the kettle with oxygen 3 times, fill the kettle with oxygen until the pressure in the kettle is 2.0MPa, turn on the mechanical stirring, the speed is 300rpm, control the temperature in the reactor to 25°C and start the reaction, keep the gas pressure in the kettle at 2.0MPa unchanged, and the reaction time is 8h. After the reaction is completed, add a certain amount of n-heptadecane internal standard and dichloromethane, take a certain amount of sample after drying with anhydrous sodium sulfate, and perform high performance liquid chromatography and gas chromatography analysis, both using internal standard method for quantification. The conversion rate of new lutein is 100%, β-damascenone is the main product, and its selectivity is 93.6%.

[0058] Example 9

[0059] Take 0.5g of phytoene and put it into a 100ml stainless steel reactor, add 5.0mg of ReO3 / mordenite catalyst (the mass ratio of the carrier to the active component is 1:10 -1 ), add 25.0g petroleum ether to the kettle. After sealing the kettle and replacing the gas in the kettle with oxygen for 3 times, fill the kettle with oxygen until the pressure in the kettle is 2.5MPa, turn on the mechanical stirring, the speed is 300rpm, control the temperature in the reactor to 25°C and start the reaction, keep the gas pressure in the kettle at 2.5MPa unchanged, and the reaction time is 10h. After the reaction is completed, add a certain amount of n-heptadecane internal standard and dichloromethane, take a certain amount of sample after drying with anhydrous sodium sulfate, and perform high performance liquid chromatography and gas chromatography analysis, both of which are quantitatively analyzed by internal standard method. The conversion rate of phytoene is 100%, isooctadienone is the main product, and its selectivity is 97.9%.

[0060] Example 10

[0061] Take 0.5g lutein, put it into a 100ml stainless steel reactor, add 10.0mg RuO2 / HZSM-5 catalyst (the mass ratio of the carrier to the active component is 1:10 -1), add 40.0g acetone to the kettle. After sealing the kettle and replacing the gas in the kettle with oxygen 3 times, fill the kettle with oxygen until the pressure in the kettle is 3.0MPa, turn on the mechanical stirring, the speed is 200rpm, control the temperature in the reactor to 25°C and start the reaction, keep the gas pressure in the kettle at 3.0MPa, and the reaction time is 4h. After the reaction is completed, add a certain amount of n-heptadecane internal standard and dichloromethane, take a certain amount of sample after drying with anhydrous sodium sulfate, and perform high performance liquid chromatography and gas chromatography analysis, both using internal standard method for quantification. The conversion rate of lutein is 100%, 3-hydroxy-β-ionone is the main product, and its selectivity is 93.8%.

[0062] Embodiment 11

[0063] Take 0.5g of β-carotene and put it into a 100ml stainless steel reactor. Add 40.0mg of ReO3 / activated carbon catalyst (the mass ratio of the carrier to the active component is 1:10). -1 ), add 45.0g of chloroform to the kettle. After sealing the kettle and replacing the gas in the kettle with oxygen 3 times, fill the kettle with oxygen until the pressure in the kettle is 3.0MPa, turn on the mechanical stirring, the speed is 100rpm, control the temperature in the reactor to 25°C and start the reaction, keep the gas pressure in the kettle at 3.0MPa unchanged, and the reaction time is 3h. After the reaction is completed, add a certain amount of n-heptadecane internal standard and dichloromethane, separate the catalyst by centrifugation, use a certain amount of dichloromethane and water to fully wash the catalyst three times, dry it at 110°C for 5h, and then carry out the next round of reaction. After each round of reaction, the liquid part after centrifugation is dried over anhydrous sodium sulfate and a certain amount of sample is taken, and high performance liquid chromatography and gas chromatography analysis are performed, and the internal standard method is used for quantification. In the four rounds of reaction, the conversion rate of β-carotene and the selectivity of the product dihydroactinolone are shown in the attached Figure 2 .

[0064] From Examples 2, 7, 11 and Examples 3, 5, 10, it can be seen that by regulating the catalytic system, both β-carotene and lutein can be selectively oxidized, and the main products are precisely controlled; the conversion rate of the raw materials is 100%, and the selectivity of the target product is more than 90%, with the highest reaching 98.5%. Figure 2 The results show that the conversion rate of β-carotene and the selectivity of the product dihydroactinolide did not decrease significantly when the ReO3 / activated carbon catalyst was reused three times.

[0065] The method for catalyzing the selective oxidation of carotenoids provided by the embodiment of the present invention, under the action of an efficient solid oxidation catalyst, a carotenoid compound undergoes a selective oxidation reaction to achieve highly selective synthesis of a target product; the method realizes highly efficient selective oxidation of carotenoids for the first time, and selective cleavage of carbon-carbon bonds at different positions in carotenoid compound molecules is achieved by regulating the catalytic system; the conversion rate of carotenoids and the selectivity of the target product are high, the conversion rate of carotenoids can reach up to more than 99%, and the selectivity of the target product can reach up to more than 98%; the process is simple, and after the catalytic selective oxidation reaction is completed, the target product can be obtained by simple separation; the solid catalyst is easy to separate from the reaction system, and after being repeatedly used three times, the activity is not significantly reduced.

[0066] So far, various embodiments of the present disclosure have been described in detail. In order to avoid obscuring the concept of the present disclosure, some details known in the art are not described. Based on the above description, those skilled in the art can fully understand how to implement the technical solution disclosed here.

[0067] Although some specific embodiments of the present disclosure have been described in detail by way of examples, it should be understood by those skilled in the art that the above examples are for illustration only and are not intended to limit the scope of the present disclosure. It should be understood by those skilled in the art that the above embodiments may be modified or some technical features may be replaced by equivalents without departing from the scope and spirit of the present disclosure. The scope of the present disclosure is defined by the appended claims.

Claims

1. A method for catalyzing the selective oxidation of carotenoids, characterized in that: include: placing a carotenoid compound in a reaction container, wherein the carotenoid compound is β-carotene; Adding a preset solvent and a solid oxidation catalyst into the reaction container, wherein the solid oxidation catalyst is a catalyst with an active component loaded on a carrier, the carrier of the solid oxidation catalyst is activated carbon, and the active component is ReO3; Filling the reaction vessel with oxygen-containing gas; The reaction container is heated and stirred for a preset time to allow the carotenoid compound to undergo a selective oxidation reaction to generate a target product, wherein the target product is dihydroactin.

2. The method for catalyzing the selective oxidation of carotenoids according to claim 1, characterized in that: The solvent is one or more of water, methanol, ethanol, glycerol, 1,3-propylene glycol, 1,2-propylene glycol, ethyl acetate, petroleum ether, acetone, ether and chloroform.

3. The method for catalyzing the selective oxidation of carotenoids according to claim 1, characterized in that: The mass ratio of the carotenoid compound to the solvent is 1:3-10 4 .

4. The method for catalyzing the selective oxidation of carotenoids according to claim 1, characterized in that: The mass ratio of the carrier to the active component of the solid oxidation catalyst is 1:10 -5 -10 -1 .

5. The method for catalyzing the selective oxidation of carotenoids according to claim 1, characterized in that: The mass ratio of the solid oxidation catalyst to the carotenoid compound is 10 -6 -10 -2 :1, the partial pressure of oxygen in the oxygen-containing gas filled into the reaction vessel is 0.01-10.0 MPa, and the oxidation reaction temperature is 0-200 o C, stirring speed is 20-1000 rpm, and reaction time is 0.1-72 h.

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