A flexible and foldable Chinese medicine wax moxibustion phase change paste capable of improving sleep and a preparation method and use method thereof

Abstract

The present invention discloses a flexible and foldable Chinese medicine wax moxibustion phase change paste capable of improving sleep, and a preparation and use method thereof, wherein the raw materials thereof include: medical paraffin, beeswax, medical vaseline and a variety of Chinese medicine powders. The present invention adjusts the flexibility, hardness and adhesion of the Chinese medicine wax moxibustion phase change paste by adding beeswax and medical vaseline, reduces the risk of low-temperature burns, increases the safety of use, improves the poor fit of the Chinese medicine wax moxibustion phase change paste to the parts with larger curvature of the human body, and improves the technical problems of high hardness after use and difficulty in folding and placing. Compared with traditional wax moxibustion paste, the use experience of the Chinese medicine wax moxibustion phase change paste is greatly improved.

Description

Technical Field

[0001] The invention belongs to the field of traditional Chinese medicine for external use, and specifically relates to a flexible and foldable traditional Chinese medicine wax moxibustion phase change paste capable of improving sleep, and a preparation method and use method thereof. Background Art

[0002] Chinese medicine wax moxibustion cream is a practical Chinese medicine external treatment technology that is derived from the integration of wax therapy and medicinal moxibustion. It combines traditional Chinese medicine with modern medical technology. It is applied to the affected area or acupoints of the human body, and utilizes the medicinal effects of Chinese medicine, the heat conduction and mechanical effects of wax therapy to achieve the effects of warming the meridians and dispersing cold, promoting blood circulation and relieving pain, and removing wind and dampness.

[0003] Ordinary wax therapy uses medical paraffin as raw material, which only has heat conduction and mechanical pressure effects, and cannot achieve the unique effects of traditional Chinese medicine. It is also brittle and easy to break, and is not easy to adhere to the uneven joint surfaces. Although traditional Chinese medicine has good penetration effect when using medicated moxibustion, it has low heat capacity and high thermal conductivity, which can easily cause burns during operation. It is also difficult to apply and prone to cracking during use.

[0004] The existing Chinese medicine wax moxibustion cream has the following problems: for the abdomen and back of the human body, the wax moxibustion cream has good adhesion, but for the parts of the legs, feet, arms and other limbs with large changes in curvature, the hot moxibustion cream has a short flexibility retention time, and it is difficult to achieve close adhesion with the human body during use, and it is easy to harden after the heat subsides, which is difficult to remove. For example, a Chinese medicine wax moxibustion phase change cream disclosed in patent CN114869946A solves the problems of melting point adjustment, easy separation of the wax base of the powder during recycling, and easy residue of low melting point wax oil on the skin, but it also has poor flexibility, and is not easy to fit with the human body when used in the parts of the human body with large changes in curvature, and has the disadvantages of easy hardening after use and difficult to remove easily. Summary of the invention

[0005] In view of the temperature and drawbacks existing in the prior art, the present invention provides a flexible and foldable Chinese medicine wax moxibustion phase change paste that can improve sleep, and a preparation and use method thereof, which uses medical paraffin, beeswax, medical vaseline and Chinese medicine fine powder to be compounded in proportion to achieve the purpose of flexible and foldable Chinese medicine wax moxibustion phase change paste.

[0006] In order to solve the above technical problems, the present invention provides the following technical solutions:

[0007] A flexible and foldable Chinese medicine wax moxibustion phase change paste capable of improving sleep, characterized in that the Chinese medicine wax moxibustion phase change paste comprises medical paraffin, medical vaseline and Chinese medicine fine powder.

[0008] Preferably, in parts by weight, each portion of the Chinese medicine wax moxibustion phase change paste contains 450-520 parts of the medical paraffin, 70-80 parts of the beeswax, 40-70 parts of the medical vaseline, and 200-300 parts of the Chinese medicine fine powder, wherein each portion of the Chinese medicine fine powder by weight includes 30-35 parts of oyster, 20-30 parts of mother of pearl, 20-30 parts of stir-fried spiny jujube seeds, 20-30 parts of processed polygala, 20-30 parts of rosin, 20-30 parts of juncea, 20-25 parts of Polygonum multiflorum, 10-20 parts of rhubarb, 10-15 parts of alum, 10-15 parts of Cyathula officinalis, 5-10 parts of Angelica dahurica, 5-10 parts of Sichuan pepper, 5-10 parts of borneol, and 5-10 parts of fennel.

[0009] In addition, the present invention also provides a method for preparing a flexible and foldable Chinese medicine wax moxibustion phase change paste capable of improving sleep, which is characterized by comprising the following steps:

[0010] (1) According to the weight ratio of each part of Chinese medicine fine powder, 30-35 parts of oyster, 20-30 parts of mother-of-pearl, 20-30 parts of stir-fried spiny jujube seeds, 20-30 parts of processed polygala, 20-30 parts of rosin, 20-30 parts of rush, 20-25 parts of Polygonum multiflorum, 10-20 parts of rhubarb, 10-15 parts of alum, 10-15 parts of Cyathula officinalis, 5-10 parts of Angelica dahurica, 5-10 parts of Sichuan pepper, 5-10 parts of borneol, and 5-10 parts of fennel are weighed, crushed into 200 mesh fine powder, mixed evenly and set aside;

[0011] (2) Then, according to the weight ratio of 450-520 parts of the medical paraffin, 70-80 parts of the beeswax, 40-70 parts of the medical vaseline, and 200-300 parts of the traditional Chinese medicine powder, the following operation is performed: the medical paraffin and beeswax are heated and melted to liquid state, mixed and stirred evenly, and then the medical vaseline is added and stirred continuously until it is completely melted and mixed evenly, and then the traditional Chinese medicine powder prepared in advance in the step (1) is added and stirred evenly, and the mixture is heated continuously until it is completely melted into a thin paste, and then poured into a clean container with a lid, sealed and stored at room temperature.

[0012] Preferably, the clean container with a lid can be a transparent lunch box made of polypropylene.

[0013] In addition, the present invention also provides a method for using a flexible and foldable Chinese medicine wax moxibustion phase change paste, which is characterized by comprising the following steps:

[0014] (1) placing the flexible and foldable Chinese medicine wax moxibustion phase change paste into a microwave oven and heating it to melt it again into a thin and flowable paste;

[0015] (2) slowly pouring the thin paste of Chinese medicinal wax moxibustion phase change paste obtained in step 1) onto a plastic wrap, spreading it into a pancake shape, standing it to cool, and after the surface of the thin paste of Chinese medicinal wax moxibustion paste loses its gloss and stops flowing, covering it with a layer of mulberry paper, and then closely attaching one side of the mulberry paper of the Chinese medicinal wax moxibustion phase change paste to a certain part of the human body skin;

[0016] (3) Then, clothes are covered on the plastic wrap or heat-insulating materials are applied. After the human body feels the heat subsides, the Chinese medicine wax moxibustion phase change paste is removed. At this time, the Chinese medicine wax moxibustion phase change paste can still maintain good flexibility and foldability;

[0017] (4) The flexible and foldable Chinese medicine wax moxibustion phase change paste pancake obtained in step 3) is directly folded, put into a container, sealed and stored at room temperature until the next use.

[0018] When the step (3) is used to improve sleep, it is preferably in close contact with the abdomen, waist, back, legs and feet of the human body.

[0019] The heat-insulating material in step (3) can preferably be selected from heat-insulating hot paraffin or a hot water bag.

[0020] The flexible and foldable Chinese medicine wax moxibustion phase change paste can be reused up to 10 times.

[0021] In the present invention, the medical paraffin has a large heat capacity and low thermal conductivity, and is not prone to burns; it dissipates heat slowly, has a strong heat preservation ability, and continuously acts to improve blood circulation; it has plasticity and viscosity, and produces a mechanical compression effect on the treatment site during the cooling and solidification process, which helps to transfer heat to deep tissues.

[0022] In the present invention, the beeswax is an important raw material for bees to build nests, has antibacterial and anti-inflammatory effects, is commonly used in the field of traditional Chinese medicine for detoxification, sore healing, tissue regeneration, analgesia, and is mainly used for ulcers that do not heal, ecthyma erosion, trauma rupture, burns, etc. The inventor unexpectedly discovered that adding a certain amount of beeswax to the phase change cream can not only increase the shelf life of the phase change cream, reduce the damage to the skin caused by long-term use of the phase change cream and possible skin infections, but also greatly improve the flexibility of the phase change cream, and the melting point range of beeswax is consistent with that of paraffin wax, and can be well mixed with paraffin wax.

[0023] In the present invention, the medical vaseline has little irritation to the skin, and can be added to the Chinese medicine wax moxibustion phase change paste to soften the Chinese medicine wax moxibustion phase change paste, and can reduce the melting point and hardness of the wax moxibustion paste, so that the Chinese medicine wax moxibustion phase change paste is soft but not separated (when melted and softened, the powder and medical paraffin, beeswax, and medical vaseline are evenly mixed, and no gravity stratification occurs), hard but not scattered (when cooled and solidified and hardened, the whole paste has good plasticity, no fracture and cracking occurs, and debris is generated to contaminate the skin), and can prevent the Chinese medicine wax moxibustion phase change paste from producing low-temperature burns to the skin when used for a long time, and avoid irreversible damage to the skin. Experimental data show that the melting point range of the Chinese medicine wax moxibustion phase change paste can be adjusted to 41-45°C by using the component ratio of Chinese medicine paraffin, beeswax, and medical vaseline of the present invention.

[0024] The oyster in the Chinese medicine powder has the effects of astringency, sedation, detoxification and analgesia; Polygonum multiflorum has the effects of nourishing blood and calming the nerves; mother of pearl has the effects of calming the liver and suppressing yang, calming the nerves and calming the nerves, nourishing the heart and nourishing the liver; stir-fried Chinese jujube seeds can nourish the heart and liver, have the effects of calming the mind and calming the nerves, have a good therapeutic effect on the discomfort symptoms caused by deficiency of heart and liver yin and blood, and can help relieve symptoms such as insomnia and palpitations caused by restlessness; processed Polygala has the effects of calming the nerves and improving intelligence, relieving insomnia and relieving depression, and can treat neurasthenia and palpitations Forgetfulness, etc.; Juffure has the effect of clearing heart fire and promoting urination, and can be used for insomnia caused by restlessness; Alum has the effect of expelling phlegm and dampness; Rhubarb has the effect of removing blood stasis, dredge meridians, unblock joints, and promoting urination and relieving stranguria; Rhubarb has the effect of purging heat and attacking knots, and can be used for sleep disorders caused by excessive heart fire; Sichuan pepper, borneol, and fennel can dispel cold and relieve pain, and have aromatic substances that can enhance the permeability of effective ingredients of traditional Chinese medicine and the comprehensive effect of traditional Chinese medicine powder, significantly improving the body's blood circulation and thus preventing the occurrence of diseases.

[0025] Modern pharmacological research and analysis show that: the oyster in the Chinese medicine powder contains rich polypeptides, polysaccharides and minerals, which have multiple activities such as lowering blood pressure, regulating immunity, improving memory, and reducing fatigue; Polygonum multiflorum contains active substances such as rhubarb, chrysophanol, polysaccharides and flavonoids, which can nourish the liver and kidney, promote blood circulation and remove blood stasis, and delay aging; Mother of pearl contains a variety of trace elements, polysaccharides and calcium substances, which can help clear liver fire and treat palpitations and insomnia; Stir-fried spiny jujube seeds contain spinosin, camellia glycoside B and other substances with sedative and hypnotic effects; Prepared Polygala tenuifolia contains a variety of saponins and glycolipid components, which are effective for memory loss. The unique phenanthrene compounds contained in rush have significant antianxiety activity; the chemical components in rosin are mainly rosin resin oil, including methyl esters and olefin compounds, as well as a small amount of terpineol ketones and alkanes, which have a sedative effect, can relieve mental tension, help people relax their body and mind, enter deep sleep, and have a certain alleviating effect on symptoms such as neurasthenia and insomnia.

[0026] The angelica dahurica powder has similar viscosity and adsorption to flour, and thus can increase the adhesion of the Chinese medicine wax moxibustion phase change paste, increase the adsorption of low-melting-point oily substances in medical paraffin, beeswax, and medical vaseline, and thus reduce their precipitation during the cooling process, thereby achieving a sticky but non-stick technical effect, that is, it can reduce the residual amount of wax oil when the Chinese medicine wax moxibustion phase change paste is separated from the skin after use, and will not stain human skin, thereby reducing the greasy feeling of the Chinese medicine wax moxibustion phase change paste on the skin.

[0027] Compared with the prior art, the present invention can achieve the following beneficial effects:

[0028] (1) The Chinese medicine wax moxibustion phase change cream of the present invention is added with a variety of Chinese medicines, which can achieve the unique functions of promoting blood circulation and removing blood stasis, regulating qi, regulating immunity, and improving sleep. It has good efficacy, quick results, safety and no side effects. The addition of medical paraffin has slow heat dissipation and strong heat preservation ability, which can accelerate drug absorption, help the sleep-inducing drug ingredients to be transferred to deep tissues with the help of heat, and continuously improve the internal environment through the stimulation of human meridians.

[0029] (2) The present invention adds medical vaseline, which is non-toxic and harmless, can improve the hardness, flexibility, and anti-cracking of the Chinese medicine wax moxibustion phase change paste, moisturize and nourish, so that the Chinese medicine wax moxibustion phase change paste has good plasticity, is soft without stratification, and is hard without loosening. It avoids the drawbacks of premature uniformity decrease and plasticity decrease when the Chinese medicine wax moxibustion phase change paste is reused, thereby increasing the number of reuses of the Chinese medicine wax moxibustion phase change paste. Experiments show that the Chinese medicine wax moxibustion phase change paste of the present invention can be stably reused 10 times.

[0030] (3) By compounding medical paraffin, beeswax and medical vaseline, the phase change melting point of the single medical paraffin-based wax moxibustion cream is further reduced. The material ratio used in this application can reduce the overall melting point of the Chinese medicine wax moxibustion phase change cream from around 53°C to the range of 41-45°C, thereby avoiding the low-temperature burns that may be caused to human skin due to long-term contact with materials above 45°C, thereby greatly increasing the safety of the use of the Chinese medicine wax moxibustion phase change cream.

[0031] (4) Angelica dahurica powder has similar stickiness and adsorption properties to flour, so it can increase the adhesion of the Chinese medicine wax moxibustion phase change paste, increase the adsorption of low-melting-point oily substances in medical paraffin and medical vaseline, and reduce the precipitation of some low-melting-point wax oils during the cooling process, thereby achieving the technical effect of sticking but not sticking, that is, it can reduce the amount of wax oil residue on the skin surface when the Chinese medicine wax moxibustion phase change paste is separated from the skin after use, and will not stain the human skin, thereby reducing the greasy feeling that is easy to produce on the skin after the use of the Chinese medicine wax moxibustion phase change paste.

[0032] (5) The existing treatment of sleep in the field of traditional Chinese medicine mainly involves intervention through Chinese herbal decoctions and external treatment methods such as massage and acupuncture. This application is based on the working principle of Chinese medicine wax moxibustion phase change paste to administer medicine by heat, and combines Chinese herbal ingredients for treating insomnia with wax bases. The small molecules of the drugs penetrate into the human microcirculation through the heat of the wax, achieving the complementarity of hot moxibustion therapy and drug intervention. It is a combination of meridian stimulation and chemical intervention, and provides a new treatment method for the treatment of insomnia in the field of traditional Chinese medicine.

[0033] (6) By adjusting the proportions of medical paraffin, beeswax, medical vaseline and Chinese medicine powder, a flexible and foldable Chinese medicine wax moxibustion phase change paste is prepared, which solves the problem that when the phase change paste is used on parts of the legs, feet, arms and other limbs with large changes in curvature, it is difficult to fit closely with human body parts due to the short flexibility time. The flexible and foldable Chinese medicine wax moxibustion phase change paste provided by the present invention is not easy to harden after the heat subsides, and can still maintain good flexibility after being removed. It is also very convenient to put away because it is flexible and foldable when recycled. Compared with the past wax moxibustion paste, it does not need to be broken up again when reheated. BRIEF DESCRIPTION OF THE DRAWINGS

[0034] Figure 1 Flexible and foldable Chinese medicine wax moxibustion phase change cream for improving sleep

[0035] Figure 2 Preparation flow chart of flexible and foldable Chinese medicine wax moxibustion phase change paste for improving sleep

[0036] Figure 3 Flow chart of the use of flexible and foldable Chinese medicine wax moxibustion phase change cream that can improve sleep

[0037] Figure 4 Partially folded form of a flexible and foldable Chinese medicine wax moxibustion phase change cream that can improve sleep

[0038] Figure 5 Comparison of the shape of the flexible and foldable Chinese medicine wax moxibustion phase change cream that can improve sleep and the Chinese medicine wax moxibustion phase change cream of CN114869946A (from left to right, the first picture shows the shape of the Chinese medicine wax moxibustion phase change cream of CN114869946A when it is removed after use, showing poor flexibility and lack of foldability; the second picture shows that the present invention can still maintain good flexibility after use and can be folded at will; the third picture shows the comparison of the Chinese medicine wax moxibustion phase change cream of CN114869946A and the Chinese medicine wax moxibustion phase change cream of the present invention when they are put away, the third left picture shows that the Chinese medicine wax moxibustion phase change cream of CN114869946A needs to be broken into pieces before it can be put away, while the third right picture shows that the patent of the present invention can be simply folded and put into a container directly.) DETAILED DESCRIPTION

[0039] Example 1

[0040] A flexible and foldable Chinese medicine wax moxibustion phase change paste for improving sleep (such as Figure 1 As shown), it includes the following components: 450g medical paraffin, 70g beeswax, 40g medical vaseline, 30g oyster, 20g mother of pearl, 20g stir-fried spiny jujube kernel, 20g processed polygala, 20g rosin, 20g rush, 20g Polygonum multiflorum, 10g rhubarb, 10g alum, 10g Cyathula, 5g Angelica dahurica, 5g Sichuan pepper, 5g borneol, and 5g fennel.

[0041] The preparation method of the above-mentioned Chinese medicine wax moxibustion phase change paste is as follows (such as Figure 2 shown):

[0042] (1) Weigh 30 g of oyster, 20 g of mother-of-pearl, 20 g of stir-fried Chinese jujube seeds, 20 g of processed Polygala, 20 g of rosin, 20 g of rush, 20 g of Polygonum multiflorum, 10 g of rhubarb, 10 g of alum, 10 g of Cyathula officinalis, 5 g of Angelica dahurica, 5 g of Sichuan pepper, 5 g of borneol, and 5 g of fennel; a total of 200 g, crush each drug into 200 mesh fine powder, mix well and set aside; then weigh 450 g of medical paraffin, 70 g of beeswax, and 40 g of medical vaseline;

[0043] (2) After the medical paraffin and beeswax described in step (1) are placed in a stainless steel container and heated in a water bath to melt until they are liquid, the medical vaseline described in step (1) is added and stirred continuously until they are completely melted and mixed evenly, and then the fine Chinese medicine powder prepared in advance in step (1) is added and stirred evenly, and the water bath is continuously heated until they are completely melted into a thin paste, and then the mixture is poured into a transparent lunch box made of polypropylene and sealed and stored at room temperature.

[0044] The method of using the flexible foldable Chinese medicine wax moxibustion phase change paste is as follows (eg Figure 3 shown):

[0045] (1) opening the lid of the sealed container containing the Chinese medicine wax moxibustion phase change paste stored at room temperature, placing it in a microwave oven, and heating it for about 5 minutes to melt it into a thin, flowable paste;

[0046] (2) slowly pouring the thin paste of Chinese medicinal wax moxibustion phase change paste obtained in step (1) onto a plastic wrap, spreading it into a pancake shape, standing it to cool, and after the surface of the thin paste of Chinese medicinal wax moxibustion phase change paste loses its gloss and stops flowing, covering it with a layer of mulberry paper, and then closely attaching one side of the mulberry paper of the Chinese medicinal wax moxibustion phase change paste to a certain part of human skin;

[0047] (3) Then cover the clothes with the plastic wrap, and after the human body feels the heat subsides, remove the Chinese medicine wax moxibustion phase change paste. At this time, the Chinese medicine wax moxibustion phase change paste still has good flexibility and can be arbitrarily curled and folded (such as Figure 4 shown);

[0048] (4) Folding the Chinese medicine wax moxibustion phase change paste obtained in step (3), placing it in a clean container with a lid, sealing it and storing it at room temperature until the next use.

[0049] like Figure 5 (From left to right) It can be seen that the folded shape of the flexible foldable Chinese herbal wax moxibustion phase change paste obtained in Example 1 after use (the second picture) is compared with the shape of the Chinese herbal wax moxibustion phase change paste of patent CN114869946A after use (the first picture). It can be seen that the flexible foldable Chinese herbal wax moxibustion phase change paste disclosed in the present invention is very flexible after use, and can be folded and placed in a transparent lunch box (the right box in the third picture). It does not need to be broken by external force before repeated use and heating, which greatly shortens the use time; while the Chinese herbal wax moxibustion phase change paste in CN114869946A has a high hardness after use and cannot be bent and folded at will. When it is reused and heated, it needs to be broken by external force before it can be reset in the container, which is extremely inconvenient when used (the left box in the third picture).

[0050] Example 2

[0051] A flexible and foldable Chinese medicine wax moxibustion phase-change paste for improving sleep comprises the following components: 480g of medical paraffin, 75g of beeswax, 55g of medical vaseline, 33g of oyster, 25g of mother-of-pearl, 25g of stir-fried spiny jujube seeds, 25g of processed polygala, 25g of rosin, 25g of rush, 23g of Polygonum multiflorum, 15g of rhubarb, 13g of alum, 13g of Cyathula officinalis, 7g of Angelica dahurica, 7g of Sichuan pepper, 7g of borneol and 7g of fennel.

[0052] The preparation method of the above-mentioned Chinese medicine wax moxibustion phase change paste is as follows:

[0053] (1) Weigh 33 g of oyster, 25 g of mother-of-pearl, 25 g of stir-fried Chinese jujube seeds, 25 g of processed Polygala tenuifolia, 25 g of rosin, 25 g of rush, 23 g of Polygonum multiflorum, 15 g of rhubarb, 13 g of alum, 13 g of Cyathula officinalis, 7 g of Angelica dahurica, 7 g of Sichuan pepper, 7 g of borneol, and 7 g of cumin; a total of 250 g, crush each drug into 200 mesh fine powder, mix well and set aside; then weigh 480 g of medical paraffin, 75 g of beeswax, and 55 g of medical vaseline;

[0054] (2) After the medical paraffin and beeswax described in step (1) are placed in a stainless steel container and heated in a water bath to melt until they are liquid, the medical vaseline described in step (1) is added and stirred continuously until they are completely melted and mixed evenly, and then the fine Chinese medicine powder prepared in advance in step (1) is added and stirred evenly, and the water bath is continuously heated until they are completely melted into a thin paste, and then the mixture is poured into a transparent lunch box made of polypropylene and sealed and stored at room temperature.

[0055] The method of using the above-mentioned flexible foldable Chinese medicine wax moxibustion phase change paste is as follows:

[0056] (1) opening the lid of the sealed container containing the Chinese medicine wax moxibustion phase change paste stored at room temperature, placing it in a microwave oven, and heating it to melt it into a flowable thin paste;

[0057] (2) slowly pouring the thin paste of Chinese medicinal wax moxibustion phase change paste obtained in step (1) onto a plastic wrap, allowing it to flow and spread into a thin pancake shape, standing and cooling, and after the surface of the thin paste of Chinese medicinal wax moxibustion phase change paste loses its gloss and stops flowing, covering it with a layer of mulberry paper, and then closely attaching one side of the mulberry paper of the Chinese medicinal wax moxibustion phase change paste to a certain part of the human body skin;

[0058] (3) Then, heat-insulating hot paraffin is applied through the plastic wrap, and after the heat felt by the human body subsides, the Chinese medicine wax moxibustion phase change paste is removed. At this time, the Chinese medicine wax moxibustion phase change paste still has good flexibility and can be curled and folded at will;

[0059] (4) folding the Chinese medicine wax moxibustion phase change paste obtained in step (3), putting it back into the container, sealing it and storing it at room temperature until the next use.

[0060] Example 3

[0061] A flexible and foldable Chinese medicine wax moxibustion phase-change paste capable of improving sleep comprises the following components: 520 g of medical paraffin, 80 g of beeswax, 70 g of medical vaseline, 35 g of oyster, 30 g of mother of pearl, 30 g of stir-fried spiny jujube seeds, 30 g of processed polygala, 30 g of rosin, 30 g of juncea, 25 g of radix polygoni multiflori, 20 g of rhubarb, 15 g of alum, 15 g of cyathula, 10 g of angelica dahurica, 10 g of Sichuan pepper, 10 g of borneol and 10 g of fennel.

[0062] The preparation method of the above-mentioned flexible and foldable Chinese medicine wax moxibustion phase change paste is as follows:

[0063] (1) Weigh 35 g of oyster, 30 g of mother-of-pearl, 30 g of stir-fried Chinese jujube kernel, 30 g of processed Polygala tenuifolia, 30 g of rosin, 30 g of rush, 25 g of Polygonum multiflorum, 20 g of rhubarb, 15 g of alum, 15 g of Cyathula officinalis, 10 g of Angelica dahurica, 10 g of Sichuan pepper, 10 g of borneol, and 10 g of fennel; a total of 300 g, crush each drug into 200 mesh fine powder, mix well and set aside; then weigh 520 g of medical paraffin, 80 g of beeswax, and 70 g of medical vaseline;

[0064] (2) After the medical paraffin and beeswax described in step (1) are placed in a stainless steel container and heated in a water bath to melt until they are liquid, the medical vaseline described in step (1) is added and stirred continuously until they are completely melted and mixed evenly, and then the fine Chinese medicine powder prepared in advance in step (1) is added and stirred evenly, and the water bath is continuously heated until they are completely melted into a thin paste, and then the mixture is poured into a transparent lunch box made of polypropylene and sealed and stored at room temperature.

[0065] The method of using the above-mentioned flexible foldable Chinese medicine wax moxibustion phase change paste is as follows:

[0066] (1) opening the lid of the sealed container containing the Chinese medicine wax moxibustion phase change paste stored at room temperature, placing it in a microwave oven, and heating it for 5 minutes to melt it into a thin, flowable paste;

[0067] (2) slowly pouring the thin paste of Chinese medicinal wax moxibustion phase change paste obtained in step (1) onto a plastic wrap, spreading it into a pancake shape, standing it to cool, and after the surface of the thin paste of Chinese medicinal wax moxibustion phase change paste loses its gloss and stops flowing, covering it with a layer of mulberry paper, and then closely attaching one side of the mulberry paper of the Chinese medicinal wax moxibustion phase change paste to a certain part of human skin;

[0068] (3) Then apply a hot water bag through the plastic wrap, and after the human body feels the heat subsides, remove the Chinese medicine wax moxibustion phase change paste. At this time, the Chinese medicine wax moxibustion phase change paste still has good flexibility and can be curled and folded at will;

[0069] (4) folding the Chinese medicine wax moxibustion phase change paste obtained in step (3), putting it back into the container, sealing it and storing it at room temperature until the next use.

[0070] The main difference between Examples 4-10 and Example 1 is that the amount ratio of medical paraffin, beeswax, medical vaseline, and Chinese medicine fine powder used is different, and the component content ratio is shown in Table 1. In order to better illustrate the improvement over the prior art, Example 3 in the previous invention CN114869946A is selected as a comparison, and the relevant material ratio is shown in Table 1.

[0071] Table 1 Material ratio of each treatment group

[0072]

[0073]

[0074] Physical and chemical properties determination

[0075] 1. Melting point test

[0076] The method for determining the melting point of the wax moxibustion cream is as follows: the Chinese medicine wax moxibustion phase change paste prepared in Examples 1-10 and Patent CN114869946A together with the box body are directly placed in a microwave oven for heating. After about 5 minutes, the Chinese medicine wax moxibustion phase change paste becomes liquid and is taken out. A thermometer (0-100°C range) is quickly placed in the liquid wax moxibustion cream, and the temperature reading is recorded every 20 seconds to obtain the temperature drop data over time. The melting point data of each embodiment are shown in Table 2.

[0077] Table 2 Melting point test data

[0078] Treatment Group Melting point(℃) Example 1 41.9 Example 2 42.4 Example 3 42.2 Example 4 41.8 Example 5 44.4 Example 6 42.1 Example 7 43.5 Example 8 44.6 Example 9 41.7 Example 10 42.6 Example 3 in CN114869946A 42.3

[0079] It can be seen from the data in Table 2 that: after mixing medical vaseline with medical paraffin and beeswax in a certain proportion, the phase change melting point of the Chinese medicine wax moxibustion phase change paste can be well reduced to meet the use requirements of <45°C and avoid the occurrence of low-temperature burns. Previous studies (CN114869946A) have shown that the influence of Chinese medicine fine powder on the melting point of Chinese medicine ointment is relatively small. When the weight ratio of the medical paraffin, the beeswax, the medical vaseline and the Chinese medicine fine powder in the present invention meets the ratio range of 450-520:70-80:40-70:200-300, the phase change temperature range of the flexible and foldable Chinese medicine wax moxibustion phase change paste can be controlled within the range of 41-45°C.

[0080] 2. Grease evaluation test

[0081] Example 8 in which medical paraffin and beeswax accounted for a relatively high proportion, Example 9 in which medical vaseline accounted for a relatively high proportion, and Example 10 in which medical paraffin, beeswax, and medical vaseline accounted for a relatively high proportion, and a certain brand of wax moxibustion cream on the market were selected as experimental objects, and compared with Example 3 in patent CN114869946A. In the experiment, 9 adult females (aged between 20 and 40 years old) were randomly selected during the outpatient clinic and divided into three groups, A, B and C, with three people in each group (numbered A1, A2, A3; B1, B2, B3; C1, C2, C3 respectively). They were asked to experience the products of Example 8, Example 9, Example 10 and Example 3 of CN114869946A and a certain brand of wax moxibustion cream, and subjectively score the greasy feeling. The subjective feeling of greasy feeling can be divided into four levels of 0-3 (0 point represents no greasy feeling, 1 point represents weak greasy feeling, 2 points represents medium greasy feeling, and 3 points represents strong greasy feeling). The participants' subjective scores of the greasy feeling of the wax moxibustion phase change cream were recorded in detail. The results are shown in Table 3.

[0082] Table 3 Subjective perception score of greasy feeling

[0083]

[0084] From the scoring results in Table 3, it can be seen that the flexible foldable Chinese medicine wax moxibustion phase change cream is not as good as Example 3 of CN114869946A in terms of the effect of controlling the greasy feeling of human skin. The reason is that in Examples 8-9, due to the addition of beeswax, the overall wax ratio has increased, but the experimental results show that the material ratio proposed in the present invention can still meet the needs of actual use in terms of greasy feeling control, and no obvious greasy feeling score results appear, which is still significantly better than the wax moxibustion cream brands on the market. The test results of Examples 8-10 also show from the side that the ratios of other embodiments proposed in the present invention can also meet the use requirements of the effect of controlling the greasy feeling of human skin.

[0085] 3. Repeated cycle test

[0086] Example 8 in which medical paraffin and beeswax accounted for a relatively high proportion, Example 3 of CN114869946A and a certain brand of nail wax moxibustion cream were selected as test objects. 750 g of the three kinds of wax moxibustion pastes were taken and heated in a microwave oven for 5 minutes respectively. After cooling and solidification, they were heated in a microwave oven for another 5 minutes, and the cycle was repeated. The hardness of the paste after each cooling and solidification was recorded (measured by measuring the needle penetration of the product. The lower the needle penetration, the higher the hardness and the worse the plasticity and flexibility. The measurement method can refer to GB / T4985-1998 "Petroleum Wax Needle Penetration Measurement Method". The domestic SYD-2801G needle penetration tester was used in the experiment, and the instrument resolution was 0.01 mm), the smell of the medicine (evaluated by the experimenter's sense of smell, and the smell of the medicine was divided into 5 levels: none, light, relatively light, relatively strong, and strong), and the uniformity (observed by the experimenter's naked eye. When the wax moxibustion paste showed a more obvious color difference between the upper and lower parts after condensation, it indicated that the uniformity of the medicine powder and the wax base was not good. The test results can be expressed in 3 levels: no difference, slight stratification, and obvious stratification). After each condensation, the smell of the medicine and the uniformity of each treatment were recorded. The results are shown in Table 3. Note: The needle penetrations of medical paraffin, beeswax and medical vaseline used in this test are 14.647mm, 32.334mm and 201.548mm respectively.

[0087] Table 3 Needle penetration, drug taste and uniformity performance

[0088]

[0089] As shown in Table 3, the flexible foldable Chinese medicine wax moxibustion phase change cream prepared by the present invention has a significantly increased needle penetration after condensation due to the addition of beeswax, which is higher than the single paraffin-based Chinese medicine wax moxibustion cream on the market, and is better than the patent CN114869946A embodiment 3, indicating that its flexibility has been greatly improved relative to existing products, and it is better in fit with the human body curve when used. Although it has significantly reduced its taste after 15 cycles, it basically meets the requirements of repeated use, and the persistence and uniformity of the taste are basically at the same level as the patent CN114869946A. The release of the taste of the medicine is not only related to the matrix, but also to the formula of the Chinese medicine fine powder. The formula of brand A is not clear, and there are also differences for the improved diseases. The amount of rosin used in the medicinal powder used by the present invention is more, so the taste of the medicine is kept for a long time. In terms of the uniformity of wax moxibustion cream, the present invention is relatively late in the stratification phenomenon relative to brand A, and the wax block reused 10 times has almost no stratification phenomenon. After 15 cycles, there will be more obvious stratification, and the uniformity is better than the existing wax moxibustion cream on the market.

[0090] It can be seen from the experimental data in Table 3 that the needle penetration of the wax moxibustion cream prepared by the material ratio of the present invention is significantly higher than the technical solution disclosed in Example 3 of Patent CN114869946A, indicating that the introduction of beeswax effectively changes the hardness of the wax moxibustion cream, and partially explains the reason why the Chinese medicine wax moxibustion phase change cream provided by the present invention can obtain flexible and foldable properties from the hardness performance parameters. Of course, the reason why the introduction of beeswax can improve the flexibility of the wax moxibustion cream is mainly due to the difference in chemical composition between it and medical paraffin, and the specific reason needs further study.

[0091] The hardness of the Chinese medicine wax moxibustion phase change paste of the present invention is less than that of a single paraffin-based wax moxibustion paste, but with the increase of the number of cyclic heating times, the low melting point and volatile components in the phase change paste will be lost more and more with the heating, thereby causing the enrichment of high melting point wax and non-volatile components, so its needle penetration will be significantly reduced after a certain number of cycles. Taking into account the above-mentioned needle penetration, medicinal taste factors and stratification phenomenon, in clinical use, in order to ensure product quality and efficacy on patients, the present invention still recommends selecting 10 cycles as the scrapping standard. The Chinese medicine wax moxibustion phase change paste after being scrapped can be recycled as a material for ordinary wax therapy, or it can be used again after further supplementing with Chinese medicine fine powder.

[0092] Clinical application effect:

[0093] Case 1

[0094] The patient, Liu, female, 69 years old, complained of difficulty falling asleep, poor sleep continuity, waking up 2-3 times every night, waking up early, having difficulty falling asleep after waking up, and sometimes having irritability, fatigue, thirst and other symptoms. Treatment measures: Acupuncture and moxibustion, the flexible foldable Chinese medicine wax moxibustion phase change paste prepared in Example 3 of the present invention is used on the patient's abdomen, back, legs and feet before going to bed every night, and the method of use is carried out in accordance with the technical scheme disclosed in the present invention. Acupuncture is completed in the hospital outpatient department, and the phase change paste treatment is completed at home. Treatment effect: The patient reported that the sleep quality has been greatly improved within 1 day, and the number of waking up at night has decreased. After 10 days, the sleep has been significantly improved, the time to fall asleep has been shortened, and there are still early awakenings, but the irritability and thirst have improved.

[0095] Case 2

[0096] The patient, Shao, female, 56 years old, complained of difficulty falling asleep, easy awakening, night sweats, dizziness and heaviness of the head, occasional palpitations, irritability, dry mouth and thirst. Treatment measures: acupuncture + decoction + flexible foldable Chinese medicine wax moxibustion phase change paste, decoction is taken at home, acupuncture and phase change paste are used in outpatient clinics, acupuncture treatment three times a week and the flexible foldable Chinese medicine wax moxibustion phase change paste made by Example 3 of the present invention is used on the patient's back, abdomen, legs and feet at the same time. Therapeutic effect: After one week, the patient's easy awakening was significantly alleviated, and after three weeks, the dizziness and heaviness of the head disappeared, and the dry mouth and thirst were alleviated. The time to fall asleep at night is longer, and the difficulty in falling asleep is alleviated.

[0097] Case 3

[0098] Patient Zhu, male, 45 years old, complained of poor sleep quality, difficulty falling asleep, emotional tension, and epigastric discomfort due to work pressure. Treatment measures: Control diet, and apply the flexible foldable Chinese medicine wax moxibustion phase change paste prepared in Example 3 of the present invention on the patient's abdomen, back and legs before going to bed every night. Treatment effect: After one week, the patient's sleep was significantly improved and mental stress was reduced.

[0099] It can be seen that the flexible and foldable Chinese medicine wax moxibustion phase change paste for improving sleep provided by the present invention has good effects when used alone or in combination with other treatment methods, enriching the clinical means of traditional Chinese medicine external treatment measures in treating insomnia and improving sleep quality.

[0100] It should be understood that although the present specification is described in terms of implementation methods, this narrative style of the specification is only for the sake of clarity, and those skilled in the art should take the specification as a whole to form other implementation methods that can be understood by those skilled in the art, which should also fall within the scope of protection of the present invention.

Claims

1. A flexible and foldable Chinese medicine wax moxibustion phase change paste that can improve sleep, characterized in that: In parts by weight, each part of the Chinese medicine wax moxibustion phase-change paste is prepared from 450-520 parts of medical paraffin, 70-80 parts of beeswax, 40-70 parts of medical vaseline, and 200-300 parts of Chinese medicine fine powder, wherein each part by weight of the Chinese medicine fine powder comprises 30-35 parts of oyster, 20-30 parts of mother of pearl, 20-30 parts of stir-fried spiny jujube seeds, 20-30 parts of processed polygala, 20-30 parts of rosin, 20-30 parts of rush, 20-25 parts of Polygonum multiflorum, 10-20 parts of rhubarb, 10-15 parts of alum, 10-15 parts of Cyathula officinalis, 5-10 parts of Angelica dahurica, 5-10 parts of Sichuan pepper, 5-10 parts of borneol, and 5-10 parts of fennel.

2. A method for preparing the flexible and foldable Chinese medicine wax moxibustion phase change paste according to claim 1, characterized in that The steps include: (1) According to the Chinese medicine fine powder, 30-35 parts of oyster, 20-30 parts of mother-of-pearl, 20-30 parts of stir-fried spiny jujube seeds, 20-30 parts of processed polygala, 20-30 parts of rosin, 20-30 parts of rush, 20-25 parts of Polygonum multiflorum, 10-20 parts of rhubarb, 10-15 parts of alum, 10-15 parts of Cyathula officinalis, 5-10 parts of Angelica dahurica, 5-10 parts of Sichuan pepper, 5-10 parts of borneol, and 5-10 parts of fennel are weighed, crushed into 200 mesh fine powder, mixed evenly and set aside; (2) Then, according to the weight ratio of 450-520 parts of the medical paraffin, 70-80 parts of the beeswax, 40-70 parts of the medical vaseline, and 200-300 parts of the traditional Chinese medicine powder, the following operation is performed: the medical paraffin and the beeswax are heated and melted to a liquid state, mixed and stirred evenly, and then the medical vaseline is added and stirred continuously until it is completely melted and mixed evenly, and then the traditional Chinese medicine powder prepared in advance in the step (1) is added and stirred evenly, and the mixture is heated continuously until it is completely melted into a thin paste, and then poured into a clean container with a lid, sealed and stored at room temperature.

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