A biomedical measuring cylinder automatic calibration method and device

Abstract

The present application provides a biomedical-oriented measuring cylinder automatic calibration method and device, which relates to the technical field of measuring cylinder calibration. The method includes obtaining the liquid level height at the circumferential position of the solution to be tested in the measuring cylinder to form circumferential liquid level height data; performing tilt demarcation point analysis based on the circumferential liquid level height data to determine the tilt demarcation data; performing calibration displacement analysis based on the tilt demarcation data to form target movement data; and performing calibration control based on the target movement data. It can automatically calibrate the measuring cylinder vertically to obtain a more accurate liquid level reading.

Description

Technical Field

[0001] This application relates to the field of graduated cylinder calibration technology, and more specifically, to an automatic graduated cylinder calibration method and apparatus for biomedicine. Background Technology

[0002] In the biopharmaceutical field, chemical methods are frequently used for experiments and the preparation of solvents such as reagents. Therefore, measuring instruments for holding solutions are indispensable tools in this field. Among these tools, the graduated cylinder plays a particularly prominent role. Not only does it serve as a container for solutions, but it also determines the volume of solutions and allows for the mixing and reaction of specific quantities of solutions. Thus, the graduated cylinder has diverse functions and a variety of uses.

[0003] Currently, the common method for measuring solution volume using graduated cylinders is to visually observe the position of the solution level on the graduated cylinder. However, this method is often prone to significant errors due to human factors. In the biopharmaceutical field, precise control of solution volume is particularly crucial and requires the highest possible accuracy. Furthermore, if the graduated cylinder is placed on a stand, its position cannot be perfectly vertical, resulting in substantial errors in the liquid level readings.

[0004] Therefore, designing an automatic calibration method and device for graduated cylinders in the biomedical field, capable of automatically calibrating the graduated cylinders vertically to obtain more accurate liquid level readings, is an urgent problem to be solved. Summary of the Invention

[0005] The purpose of this application is to provide an automatic calibration method for graduated cylinders in the biopharmaceutical industry. This method adjusts the verticality of the graduated cylinder by using the effective value of the circumferential liquid level height as the reference height for calibration, accurately locating the specific position where the required calibration angle needs to be determined. Furthermore, a reasonable liquid level data processing method is employed to improve the accuracy of data analysis. Simultaneous adjustment actions at different adjustment positions ensure the accuracy of automatic calibration. In addition, using air pressure as the power source for adjustment is a fluid-based adjustment method that matches changes in the solution level, achieving smoothness and accuracy in adjustment.

[0006] The purpose of this application is also to provide an automatic graduated cylinder calibration device for biomedicine. This device uses a supporting rotating assembly to hold the graduated cylinder containing the solution, and a level sensor collects the liquid level in the graduated cylinder. The rotating drive assembly rotates the supporting rotating assembly, thereby causing the graduated cylinder to rotate. This allows the level sensor to obtain circumferential liquid level information of the graduated cylinder when it is fixed in place, thus determining whether the liquid level in the graduated cylinder is horizontal. The angle position of the supporting rotating assembly is adjusted by the movement and inflation of the air inlet ring wall assembly and the calibration adjustment assembly to keep the graduated cylinder vertical. This allows for liquid level calibration each time the graduated cylinder is used to measure the solution, improving the accuracy of solution volume data acquisition and completely eliminating human error caused by placing the graduated cylinder on the supporting rotating assembly each time. Furthermore, using a level sensor to read the liquid level effectively avoids errors caused by human reading, further improving the accuracy of the graduated cylinder reading.

[0007] In a first aspect, embodiments of this application provide an automatic calibration method for graduated cylinders in the biomedical field, comprising: acquiring the liquid level height of the solution to be tested in the graduated cylinder at a circumferential position to form circumferential liquid level height data; performing tilt boundary point analysis based on the circumferential liquid level height data to determine tilt boundary data; performing calibration displacement analysis based on the tilt boundary data to form target movement data; and performing calibration control based on the target movement data.

[0008] In this embodiment, the method adjusts the verticality of the graduated cylinder by using the effective value of the circumferential liquid level height as the reference height for calibration, accurately locating the specific position where the angle to be calibrated needs to be determined. Furthermore, a reasonable liquid level data processing method is employed to improve the accuracy of data analysis. Simultaneous synchronization of adjustment actions at different adjustment positions ensures the accuracy of automatic calibration. Additionally, using air pressure as the power source for adjustment is a fluid-based adjustment method that matches changes in the solution level, achieving smoothness and accuracy in the adjustment.

[0009] As one possible implementation, the liquid level height of the solution to be tested in the measuring cylinder at the circumferential position is obtained to form circumferential liquid level height data, including: obtaining the original liquid level height of the solution to be tested in the measuring cylinder at the circumferential position, and establishing an original angular displacement-height relationship diagram; smoothing the height data in the original angular displacement-height relationship diagram to obtain an effective angular displacement-height relationship diagram.

[0010] In this embodiment of the application, the height data of the solution to be tested is transformed into a visual planar graph. On the one hand, this allows for a more intuitive extraction of data patterns during data analysis, thereby forming a reasonable data processing method. On the other hand, the planar graph provides an intuitive reference basis for subsequent in-depth calibration data calculation and analysis, ensuring the correctness and rationality of the analysis.

[0011] As one possible implementation, the height data in the original angular displacement-height relationship map is smoothed to obtain an effective angular displacement-height relationship map. This includes setting an angular displacement step size k0, where the step size takes an odd number of angular displacements Ɵ over the entire angular displacement. n The corresponding height parameter h n Where n is an odd natural number; the vector values ​​between two adjacent height parameters are sequentially obtained, and a matching degree analysis is performed on the obtained vector values. Based on the analysis results, the fitting relationship function F0(Ɵ) is obtained; the angular displacement step size change c and the change threshold m are set; starting with the angular displacement step size, the step size is adjusted at least a number of times, with each adjusted step size value formed based on the previous adjusted step size value and the angular displacement step size change c. A matching degree analysis is performed based on the adjusted step size, and the adjustment fitting relationship function F0(Ɵ) is obtained based on the analysis results. z (Ɵ), where z≥m; combining the fitting relationship function F0(Ɵ) and the adjusted fitting relationship function F z (Ɵ), obtain the effective diagram of angular displacement-height relationship.

[0012] In this embodiment, the processing of the angular displacement-height relationship function is performed while fully considering the characteristics of liquid height data. It is known that the circumferential height liquid level data formed by the liquid is inherently smooth and continuous due to the liquid's fluidity. However, when extracting circumferential liquid level data, considering the influence of environmental and equipment factors, the obtained data may have certain deviations; that is, some data may deviate from the theoretical liquid level function curve, resulting in unevenness at that point. By using the step size as a variable for data extraction and analysis, and then comprehensively analyzing the results after multiple step size changes, it is possible to effectively avoid the errors caused by simultaneously acquiring erroneous data. Furthermore, by conducting multiple data acquisition and analysis sessions, the bias in data processing is reduced, thereby greatly improving the accuracy of data analysis.

[0013] One possible implementation involves performing a matching degree analysis on the acquired vector values ​​and obtaining the fitting relationship function F0(Ɵ) based on the analysis results. Another approach is to perform a matching degree analysis based on the adjusted step size value and obtain the adjusted fitting relationship function F based on the analysis results. z When (Ɵ), the following analysis is performed: when all the obtained vector values ​​are paired and equal, a function is fitted based on the vector values; when the obtained vector values ​​are not equal at symmetrical angular displacement positions, then: set an adjustment variable, and adjust the symmetrical position of the angular displacement synchronously based on the adjustment variable, wherein the adjusted angular displacement is between adjacent initial angular displacement values; obtain vector values ​​based on the adjusted height values ​​until the obtained vector values ​​form a pairwise matching result; perform function fitting based on the matching result data formed after adjustment.

[0014] In this embodiment, it is inevitable that during the function fitting process, deviations in the height data at symmetrical positions will cause deviations in the fitted function due to biases in the acquired data. Therefore, in cases of symmetrical mismatch, adjusting the position for further accurate data acquisition can greatly improve the accuracy of data analysis and avoid the waste of resources caused by discarding the analysis due to errors.

[0015] As one possible implementation, a combination of the fitting relationship function F0(Ɵ) and the adjusted fitting relationship function F z (Ɵ), to obtain an effective graph of angular displacement-height relationship, including: fitting the relationship function F0(Ɵ) and adjusting the fitting relationship function F z (Ɵ) is calculated using the following formula to obtain the angular displacement-height relationship function F(Ɵ): F(Ɵ) = (F0(Ɵ) + ΣF z (Ɵ)) / (z+1); An angular displacement-height relationship diagram is formed based on the angular displacement-height relationship function F(Ɵ).

[0016] In this embodiment, a specific method for calculating the angular displacement-height relationship function is provided. The fitted relationship function and the adjusted relationship function are then subjected to another comprehensive processing after acquisition, i.e., the average value is used as a valid reference value, which can further improve the data accuracy of the angular displacement-height relationship function.

[0017] As one possible approach, based on the circumferential liquid level height data, an inclination boundary point analysis is performed to determine the inclination boundary data, including: determining the average height H based on the effective diagram of the angular displacement-height relationship. p and average height H p The two corresponding symmetrical angular displacement positions Ɵ1 and Ɵ2 are used as references to determine the upper height extreme value H in the effective diagram of the angular displacement-height relationship. max Lower height extreme value H min And the corresponding angular displacement position; based on the upper height extreme value H max Lower height extreme value H min and average height H p To obtain the maximum tilt angle α:

[0018] , where R is the effective liquid column radius.

[0019] In this embodiment, due to the characteristics of the liquid surface tilt, the tilt angle of the liquid surface is always symmetrical on both sides of the line connecting the equilibrium points. Therefore, by obtaining the tilt angles on both sides and using the average of the two as the final tilt angle, the accuracy of the maximum tilt angle data can be greatly improved, and the influence of errors in the data acquisition process on the final maximum tilt angle data can be avoided.

[0020] As one possible implementation, based on the tilt boundary data, the calibration displacement is analyzed to form target movement data, including: acquiring the initial placement tilt angle β, the movement reference elevation H0, and combining it with the maximum tilt angle α to obtain the target's main movement distance S; and acquiring the angular displacement difference Ɵ between the auxiliary position and the main position. x And establish a synchronization function y=F(x, y) for the movement distance between the primary and auxiliary positions. x ), where y∈[0,S], and x represents the auxiliary movement distance parameter of the auxiliary position.

[0021] In this embodiment, the automatic calibration process considers situations where not only the maximum tilt angle is adjusted, but other positions also coordinate for automatic calibration. Therefore, it is necessary to consider the synchronicity of the actions between different positions during automatic calibration. This is to avoid situations where different action ratios cause new tilt positions, affecting the automatic calibration of the measuring cylinder and creating new deviations.

[0022] As one possible implementation, the target main movement distance S is obtained by the following formula:

[0023] .

[0024] In this application embodiment, a method for calculating the main moving distance is specifically disclosed. Combined with an automatic calibration device, it can quickly determine the action steps and action limitations of the automatic calibration device during calibration, thereby achieving high accuracy of automatic calibration.

[0025] As one possible implementation, calibration control is performed based on target movement data, including: determining the main inflation rate P of the main position based on the target main movement distance S. 主 According to the main inflation rate P 主 Synchronization function for movement distance: y=F(x, Ɵ) x Determine the auxiliary inflation rate P at the auxiliary position. 辅 According to the main inflation rate P 主 And auxiliary inflation rate P 辅 Control the inflation process.

[0026] In this embodiment, automatic calibration is performed using air pressure adjustment. Since both the air pressure and the solution are liquids, the adjustment exhibits high compatibility. Furthermore, considering the synchronicity of the inflation adjustment at different positions improves the accuracy of the adjustment.

[0027] Secondly, embodiments of this application provide an automatic graduated cylinder calibration device for biomedicine, employing the automatic graduated cylinder calibration method for biomedicine described in the first aspect. The device includes a mounting base, a liquid level sensor, an air inlet ring wall assembly, a calibration adjustment assembly, a rotation drive assembly, and a supporting rotation assembly. The mounting base has a mounting groove. The rotation drive assembly is disposed in the mounting groove. The supporting rotation assembly is rotatably connected to the rotation drive assembly and is located on the mounting base. The air inlet ring wall assembly is disposed on the mounting base around the supporting rotation assembly. The calibration adjustment assembly is disposed on the mounting base around the supporting rotation assembly and abuts against the supporting rotation assembly. The calibration adjustment assembly is rotatably connected to the rotation drive assembly. The calibration adjustment assembly has an adjustment air inlet chamber, which is connected to the air inlet ring wall. The liquid level sensor is disposed on the mounting base and is located around the air inlet ring wall assembly. The rotation drive assembly controls the rotation of the supporting rotation assembly, the liquid level sensor collects the graduated cylinder liquid level information on the supporting rotation assembly, and controls the rotation and positioning of the calibration adjustment assembly based on the liquid level information. The air inlet ring wall assembly introduces air into the adjustment air inlet chamber to control the supporting rotation assembly for calibration.

[0028] In this embodiment, the device uses a supporting rotating assembly to hold a graduated cylinder containing the solution, and a level sensor collects the liquid level in the graduated cylinder. The rotating drive assembly rotates the supporting rotating assembly, thereby causing the graduated cylinder to rotate. This allows the level sensor to obtain circumferential liquid level information of the graduated cylinder when it is fixed in place, thus determining whether the liquid level in the graduated cylinder is horizontal. The angle of the supporting rotating assembly is adjusted by the movement and inflation of the air inlet ring wall assembly and the calibration adjustment assembly to keep the graduated cylinder vertical. This allows for liquid level calibration each time the graduated cylinder is used to measure the solution, improving the accuracy of solution volume data acquisition and completely eliminating human error caused by placing the graduated cylinder on the supporting rotating assembly each time. Furthermore, using a level sensor to read the liquid level effectively avoids errors caused by human reading, further improving the accuracy of the graduated cylinder reading.

[0029] The beneficial effects of the automatic calibration device and method for graduated cylinders in the biomedical field provided in this embodiment are as follows:

[0030] An automatic calibration method for graduated cylinders in the biopharmaceutical industry adjusts the verticality of the cylinder by using the effective value of the circumferential liquid level as the reference height for calibration. This allows for precise positioning of the angle requiring calibration. Furthermore, a reasonable liquid level data processing method improves the accuracy of data analysis. Simultaneous adjustment actions at different positions ensure the accuracy of automatic calibration. Additionally, utilizing air pressure as the power source for adjustment, a fluid-based adjustment method, matches changes in the solution level, achieving smooth and accurate adjustments.

[0031] An automatic graduated cylinder calibration device for biomedicine uses a supporting rotating assembly to hold the graduated cylinder containing the solution, and a level sensor to collect the solution level in the cylinder. A rotation drive assembly rotates the supporting rotating assembly, which in turn rotates the graduated cylinder, allowing the level sensor to obtain circumferential liquid level information when the cylinder is fixed in place, thus determining whether the liquid level is horizontal. The angle of the supporting rotating assembly is adjusted by the movement and inflation of the air inlet ring wall assembly and calibration adjustment assembly to ensure the graduated cylinder is vertical. This level calibration is performed every time the graduated cylinder is used to measure the solution, improving the accuracy of solution volume data acquisition and completely eliminating human error caused by placing the graduated cylinder on the supporting rotating assembly each time. Furthermore, using a level sensor to read the liquid level effectively avoids errors caused by human reading, further improving the accuracy of the graduated cylinder readings. Attached Figure Description

[0032] To more clearly illustrate the technical solutions of the embodiments of this application, the accompanying drawings used in the embodiments of this application will be briefly introduced below. It should be understood that the following drawings only show some embodiments of this application and should not be regarded as a limitation of the scope. For those skilled in the art, other related drawings can be obtained based on these drawings without creative effort.

[0033] Figure 1 A step diagram illustrating the automatic calibration method for graduated cylinders in the biomedical field provided in this application embodiment;

[0034] Figure 2 A first-view structural schematic diagram of an automatic graduated cylinder calibration device for biomedicine provided in an embodiment of this application;

[0035] Figure 3 A second-view structural schematic diagram of an automatic graduated cylinder calibration device for biomedicine provided in an embodiment of this application;

[0036] Figure 4 This application provides a schematic diagram of the air intake rotation drive mechanism of an automatic graduated cylinder calibration device for biomedicine.

[0037] Label:

[0038] 01. Mounting base; 11. Mounting slot; 02. Liquid level sensor; 03. Inlet ring wall assembly; 31. Inlet port; 32. Exhaust port; 33. Inlet sealing ring; 34. Exhaust sealing ring; 35. Inlet ring groove; 36. Exhaust ring groove; 04. Calibration and adjustment assembly; 41. Semi-circular sealing grid; 42. Adjusting sealing grid; 43. Elastic connector; 05. Rotary drive assembly; 51. Rotary drive motor; 52. Liquid level rotating ball head; 521. Positioning protrusion; 53. Inlet rotary drive mechanism; 531. Rotating sleeve; 532. Compression spring; 533. Drive connecting rod; 06. Support rotation assembly; 61. Rotating base; 62. Adjusting plate; 63. Upper support rod; 64. Covering sleeve; 65. Elastomer. Detailed Implementation

[0039] The technical solutions in the embodiments of this application will now be described with reference to the accompanying drawings.

[0040] refer to Figure 1 This application provides an automatic calibration method for graduated cylinders in the biopharmaceutical industry. This method adjusts the verticality of the graduated cylinder by using the effective value of the circumferential liquid level height as the reference height for calibration, accurately locating the specific position where the required calibration angle is needed. Furthermore, a reasonable liquid level data processing method is employed to improve the accuracy of data analysis. Simultaneous adjustment actions at different adjustment positions ensure the accuracy of automatic calibration. In addition, using air pressure as the power source for adjustment is a fluid-based adjustment method that matches changes in the solution level, achieving smooth and accurate adjustment.

[0041] The automatic calibration method for graduated cylinders in the biopharmaceutical industry includes the following steps:

[0042] S1: Obtain the liquid level height of the solution to be tested in the measuring cylinder at the circumferential position to form circumferential liquid level height data.

[0043] This step includes: obtaining the original liquid level height of the solution to be tested in the measuring cylinder at the circumferential position, and establishing the original angular displacement-height relationship diagram; smoothing the height data in the original angular displacement-height relationship diagram to obtain the effective angular displacement-height relationship diagram.

[0044] Transforming the height data of the solution under test into a visual planar graph allows for a more intuitive extraction of data patterns during data analysis, leading to a more reasonable data processing approach. Furthermore, the planar graph provides a clear reference for subsequent in-depth calibration data calculations and analysis, ensuring the accuracy and rationality of the analysis.

[0045] The process involves smoothing the height data in the original angular displacement-height relationship map to obtain an effective angular displacement-height relationship map. This includes setting an angular displacement step size k0, where the step size takes an odd number of angular displacements Ɵ over the entire angular displacement. n The corresponding height parameter h n Where n is an odd natural number; the vector values ​​between two adjacent height parameters are sequentially obtained, and a matching degree analysis is performed on the obtained vector values. Based on the analysis results, the fitting relationship function F0(Ɵ) is obtained; the angular displacement step size change c and the change threshold m are set; starting with the angular displacement step size, the step size is adjusted at least a number of times, with each adjusted step size value formed based on the previous adjusted step size value and the angular displacement step size change c. A matching degree analysis is performed based on the adjusted step size, and the adjustment fitting relationship function F0(Ɵ) is obtained based on the analysis results. z (Ɵ), where z≥m; combining the fitting relationship function F0(Ɵ) and the adjusted fitting relationship function F z (Ɵ), obtain the effective diagram of angular displacement-height relationship.

[0046] The processing of the angular displacement-height relationship function is carried out after fully considering the characteristics of liquid height data. It is known that the circumferential liquid level data formed by the liquid is inherently smooth and continuous due to the liquid's fluidity. However, when extracting circumferential liquid level data, considering the influence of environmental and equipment factors, the obtained data may have certain deviations; that is, some data may deviate from the theoretical liquid level function curve, resulting in unevenness at those points. By using the step size as a variable for data extraction and analysis, and synthesizing the results after multiple step size changes, it is possible to effectively avoid the errors caused by simultaneously acquiring erroneous data. Furthermore, by conducting multiple data acquisitions and analyses, it reduces data processing bias, thereby significantly improving the accuracy of data analysis.

[0047] A matching degree analysis is performed on the acquired vector values, and the fitting relationship function F0(Ɵ) is obtained based on the analysis results. A matching degree analysis is also performed based on the adjusted step size value, and the adjusted fitting relationship function F is obtained based on the analysis results. z When (Ɵ), the following analysis is performed: when all the obtained vector values ​​are paired and equal, a function is fitted based on the vector values; when the obtained vector values ​​are not equal at symmetrical angular displacement positions, then: set an adjustment variable, and adjust the symmetrical position of the angular displacement synchronously based on the adjustment variable, wherein the adjusted angular displacement is between adjacent initial angular displacement values; obtain vector values ​​based on the adjusted height values ​​until the obtained vector values ​​form a pairwise matching result; perform function fitting based on the matching result data formed after adjustment.

[0048] Of course, during the function fitting process, deviations in the height data at symmetrical locations will inevitably cause deviations in the fitted function due to biases in the data acquisition. Therefore, when encountering symmetrical mismatches, adjusting the location for further accurate data acquisition can greatly improve the accuracy of data analysis and avoid the waste of resources caused by discarding the analysis due to errors.

[0049] In addition, the combined fitting relationship function F0(Ɵ) and the adjusted fitting relationship function F z (Ɵ), to obtain an effective graph of angular displacement-height relationship, including: fitting the relationship function F0(Ɵ) and adjusting the fitting relationship function F z (Ɵ) is calculated using the following formula to obtain the angular displacement-height relationship function F(Ɵ): F(Ɵ) = (F0(Ɵ) + ΣF z (Ɵ) / (z+1); An angular displacement-height relationship graph is generated based on the angular displacement-height relationship function F(Ɵ). The specific calculation method for the angular displacement-height relationship function is provided. After obtaining the fitted relationship function and the adjusted relationship function, a further comprehensive processing is performed, using the average as a valid reference value, which can further improve the data accuracy of the angular displacement-height relationship function.

[0050] S2: Based on the circumferential liquid level height data, perform tilt boundary point analysis to determine the tilt boundary data.

[0051] Based on the circumferential liquid level height data, an analysis of the tilt boundary point is performed to determine the tilt boundary data, including: determining the average height H based on the effective diagram of the angular displacement-height relationship. p and average height H p The two corresponding symmetrical angular displacement positions Ɵ1 and Ɵ2 are used as references to determine the upper height extreme value H in the effective diagram of the angular displacement-height relationship. max Lower height extreme value H min And the corresponding angular displacement position; based on the upper height extreme value H max Lower height extreme value H min and average height H p To obtain the maximum tilt angle α:

[0052] , where R is the effective liquid column radius.

[0053] Due to the tilted nature of the liquid surface, the tilt angle of the liquid surface is always symmetrical on both sides of the line connecting the equilibrium points. Therefore, by obtaining the tilt angles on both sides and using the average of the two as the final tilt angle, the accuracy of the maximum tilt angle data can be greatly improved, and the influence of errors in the data acquisition process on the final maximum tilt angle data can be avoided.

[0054] S3: Based on the tilt boundary data, perform calibration displacement analysis to generate target movement data.

[0055] Based on the tilt boundary data, the calibration displacement is analyzed to form target movement data, including: acquiring the initial placement tilt angle β, the movement reference elevation H0, and combining it with the maximum tilt angle α to obtain the target's main movement distance S; and obtaining the angular displacement difference Ɵ between the auxiliary position and the main position. x And establish a synchronization function y=F(x, y) for the movement distance between the primary and auxiliary positions. x ), where y∈[0,S], and x represents the auxiliary movement distance parameter of the auxiliary position.

[0056] This application considers situations where automatic calibration involves not only adjusting the maximum tilt angle but also coordinating with other positions. Therefore, it's necessary to consider the synchronicity of the actions between different positions during automatic calibration. This is to prevent discrepancies in the actions from causing new tilt positions and affecting the automatic calibration of the graduated cylinder.

[0057] The target's main movement distance S is obtained by the following formula:

[0058] Specifically, a method for calculating the main moving distance is disclosed. Combined with an automatic calibration device, it can quickly determine the action steps and action limitations of the automatic calibration device during calibration, achieving high accuracy in automatic calibration.

[0059] S4: Calibration control based on target movement data.

[0060] Calibration control is performed based on target movement data, including: determining the main inflation rate P of the main position based on the main target movement distance S. 主 According to the main inflation rate P 主 Synchronization function for movement distance: y=F(x, Ɵ) x Determine the auxiliary inflation rate P at the auxiliary position. 辅 According to the main inflation rate P 主 And auxiliary inflation rate P 辅 Control the inflation process.

[0061] Automatic calibration is achieved by using air pressure adjustment, and since both the air pressure and the solution are liquids, the adjustment has a high degree of matching. Furthermore, considering the synchronicity of the inflation adjustment at different positions improves the accuracy of the adjustment.

[0062] refer to Figures 2-4This application also provides an automatic graduated cylinder calibration device for biomedicine. This device is applied to an automatic graduated cylinder calibration method for biomedicine provided in this application. The device uses a supporting rotating assembly 06 to hold the graduated cylinder containing the solution, and a liquid level collector 02 collects the liquid level of the solution in the graduated cylinder. The rotating drive assembly 05 rotates the supporting rotating assembly 06, thereby causing the graduated cylinder to rotate. This allows the liquid level collector 02 to obtain circumferential liquid level information of the graduated cylinder when it is fixed in place, thus determining whether the liquid level of the graduated cylinder is horizontal. The angular position of the supporting rotating assembly 06 is adjusted by the movement and inflation of the air inlet ring wall assembly 03 and the calibration adjustment assembly 04 to keep the graduated cylinder vertical. This allows for liquid level calibration each time the graduated cylinder is used to measure the solution, improving the accuracy of solution volume data acquisition and completely eliminating human error caused by placing the graduated cylinder on the supporting rotating assembly 06 each time. Furthermore, using the liquid level collector 02 to read the liquid level effectively avoids errors caused by human reading, further improving the accuracy of the graduated cylinder reading.

[0063] An automatic graduated cylinder calibration device for biomedicine includes a mounting base 01, a liquid level sensor 02, an air inlet ring wall assembly 03, a calibration adjustment assembly 04, a rotary drive assembly 05, and a supporting rotary assembly 06. The mounting base 01 has a mounting groove 11. The rotary drive assembly 05 is disposed in the mounting groove 11. The supporting rotary assembly 06 is rotatably connected to the rotary drive assembly 05 and is located on the mounting base 01. The air inlet ring wall assembly 03 is disposed on the mounting base 01 around the supporting rotary assembly 06. The calibration adjustment assembly 04 is disposed on the mounting base 01 around the supporting rotary assembly 06, and the calibration adjustment assembly... 04 supports the rotating assembly 06; the calibration and adjustment assembly 04 is rotatably connected to the rotation drive assembly 05; the calibration and adjustment assembly 04 is provided with an adjustment air inlet chamber, and the adjustment air inlet chamber is connected to the air inlet ring wall; the liquid level collector 02 is set on the mounting base 01, and the liquid level collector 02 is located on the periphery of the air inlet ring wall assembly 03; the rotation drive assembly 05 controls the rotation of the supporting rotating assembly 06, the liquid level collector 02 collects the liquid level information of the measuring cylinder on the supporting rotating assembly 06, and controls the rotation and positioning of the calibration and adjustment assembly 04 according to the liquid level information; the air inlet ring wall assembly 03 introduces air into the adjustment air inlet chamber to control the supporting rotating assembly 06 for calibration.

[0064] The specific structure of each sub-component is described in detail below:

[0065] The intake ring wall assembly 03 includes an intake ring wall, an intake sealing ring 33, and an exhaust sealing ring 34; the intake ring wall is arranged around the support rotation assembly 06; the calibration adjustment assembly 04 is connected around the support rotation assembly 06, and the calibration adjustment assembly 04 is coaxially arranged with the support rotation assembly 06 and located inside the intake ring wall; one end of the calibration adjustment assembly 04 abuts against the adjustment plate 62 on the support rotation assembly 06, and the other end is arranged on the mounting base 01; an intake hole 31 and an exhaust hole 32 are spaced apart around the axis of the intake ring wall; an intake one-way valve is provided in the intake hole 31; and an exhaust valve is provided in the exhaust hole 32. A one-way valve is provided; an intake ring groove 35 and an exhaust ring groove 36 are provided on the inner side wall of the intake ring wall; the intake ring groove 35 is connected to the intake hole 31, and the intake sealing ring 33 is rotatably disposed at the groove opening of the intake ring groove 35 to seal the intake ring groove 35; the exhaust ring groove 36 is connected to the exhaust hole 32, and the exhaust sealing ring 34 is disposed at the groove opening of the exhaust ring groove 36 to seal the exhaust ring groove 36; intake pipes are provided at intervals on the intake sealing ring 33; the intake ring groove 35 is connected to the adjustment intake chamber through the intake pipes; exhaust pipes are provided at intervals on the exhaust sealing ring 34; the exhaust ring groove 36 is connected to the adjustment intake chamber through the exhaust pipes.

[0066] The air intake ring wall is positioned around the axis of the supporting rotating assembly 06, ensuring standardized adjustments at every angular position. The air intake port 31 and exhaust port 32 are used to supply air to and exhaust it into the adjustment air intake chamber on the calibration adjustment assembly 04, thereby adjusting the angle of the supporting rotating assembly 06. The air intake ring groove 35 and exhaust ring groove 36 allow for air intake and exhaust adjustments after the calibration adjustment assembly 04 has rotated to any position, reducing the number of air intake ports 31 and 32 required. It can be understood that the air intake pipe on the air intake ring groove 35 and the exhaust pipe on the exhaust ring groove 36 can move with the adjustment air intake chamber on the calibration adjustment assembly 04, facilitating the supply of air for the adjustment air intake chamber. Furthermore, considering that the liquid level tilt is greatest at the furthest point, angle adjustments also require providing different air pressures at different positions or areas to achieve balanced adjustment. Therefore, an intake plug is set to divide the intake ring groove 35. When adjusting the angle, the intake port 31 is used to provide different air pressures to the intake ring groove 35 cavity in different areas to achieve the purpose of balance adjustment.

[0067] The air inlets 31 are evenly spaced around the axis of the air inlet ring wall, and the angle between adjacent air inlets 31 relative to the axis of the air inlet ring wall is less than 45 degrees. The exhaust ports 32 are evenly spaced around the axis of the air inlet ring wall, and the angle between adjacent exhaust ports 32 relative to the axis of the air inlet ring wall is less than 45 degrees. It should be noted that the air inlets 31 and exhaust ports 32, especially the air inlets 31, need to ensure that they can provide gas of different pressures to the adjustment air inlet chamber on the calibration adjustment assembly 04 under any circumstances after the calibration adjustment assembly 04 is moved. Therefore, the angle setting between adjacent air inlets 31 is based on the change of liquid level in the measuring cylinder. Because when the liquid level is tilted, the average liquid level point is basically symmetrical, that is, on both sides of the plane passing through the axis of the measuring cylinder, more precisely, on both sides of the plane passing through the axis of the cylindrical liquid in the measuring cylinder, a liquid level change with one side tilting downward and the other tilting upward will be formed. Based on this, the vertical adjustment of the measuring cylinder basically requires tilting half of the measuring cylinder column. Thus, at least one air inlet 31 needs to be set within a range of 90 degrees. On the other hand, considering the different air pressure intake adjustments in the 35-section intake ring groove, the angle between adjacent intake holes 31 must be at least less than the angle between adjacent adjustment intake chambers to allow for different air pressure adjustments in each adjustment intake chamber. In this application, the angle between adjustment intake chambers is set to 45 degrees, so the angle between adjacent intake holes 31 relative to the intake ring wall axis needs to be less than 45 degrees. In this application, the angle between adjacent intake holes 31 relative to the intake ring wall axis is 30 degrees, which ensures that each independent intake ring groove 35 has at least two intake holes 31, further improving intake efficiency compared to a single intake hole 31 and enabling faster angle adjustments. For the exhaust hole 32, its arrangement can be the same as the intake hole 31, or only one can be provided for common exhaust operations.

[0068] The calibration and adjustment assembly 04 includes a sealing grid and an elastic connector 43; the sealing grids are spaced apart around the support rotation assembly 06, and multiple sealing grids are located only on the semi-circular side of the ring around the support rotation assembly 06; the end of the sealing grid away from the mounting base 01 forms a retaining slope, and the retaining slope contacts the adjustment plate 62; an elastic connector 43 connects adjacent sealing grids; the symmetrically arranged sealing grids are semi-circular sealing grids 41; no adjustment intake chamber is opened on the semi-circular sealing grid 41; the non-symmetrically arranged sealing grids are adjustment sealing grids; an adjustment intake chamber is opened on the side of the adjustment sealing grid near the intake ring wall; the adjustment intake chamber is connected to the intake ring groove 35 through the intake pipe; the adjustment intake chamber is connected to the exhaust ring groove 36 through the exhaust pipe.

[0069] The calibration adjustment component 04 takes various forms. In this application, the calibration adjustment component 04 includes a sealing grid and an elastic connector 43. The sealing grid is only set on a semicircle of its circumference. This is because the vertical adjustment of the measuring cylinder basically requires tilting half of the cylinder column. Therefore, if there is a sealing grid on the other side, it will block the adjustment effect. In addition, the sealing grid serves two purposes: adjusting the angle and defining the position during adjustment. Therefore, the sealing grid is divided into a semicircular sealing grid 41 and an adjustment sealing grid 42. The semicircular sealing grid 41 is mainly used to determine the adjustment range. Each time an adjustment is performed, the semicircular sealing grid 41 needs to be moved to the boundary of the adjustment range to ensure the accuracy of the adjustment range. The adjustment sealing grid 42 is adjusted by adjusting the air inlet chamber. Considering that tilting adjustment requires providing different air pressures to the adjustment air inlet chamber at different positions, and in conjunction with the position of the air inlet 31, the adjustment sealing grids 42 are evenly spaced in this application, and there are three of them.

[0070] The sealing grilles are evenly spaced around the rotating support assembly 06, and the angle between adjacent sealing grilles relative to the axis of the intake ring wall is greater than the angle between adjacent intake holes 31 relative to the axis of the intake ring wall. Only when the angle between the sealing grilles is greater than the angle between the intake holes 31 can it be ensured that the adjustment intake chamber on each sealing grille has a corresponding intake hole 31 to provide air pressure.

[0071] The rotary drive assembly 05 includes a rotary drive motor 51, a liquid level rotary ball head 52, and an air intake rotary drive mechanism 53. The rotary drive motor 51 is disposed in the mounting groove 11, and the output shaft of the drive motor is rotatably connected to the supporting rotary assembly 06 through the liquid level rotary ball head 52. A positioning protrusion 521 is provided on the liquid level rotary ball head 52 along the axis of the output shaft of the rotary drive motor 51. The positioning protrusion 521 cooperates with the positioning groove on the supporting rotary assembly 06. The air intake rotary drive mechanism 53 is sleeved on the rotary drive motor 51, and one end of the air intake rotary drive mechanism 53 passes through the arc-shaped adjustment hole on the mounting base 01 and is movably connected to the sealing grille.

[0072] The rotary drive assembly 05 comprises two parts: one part drives the rotation of the support rotary assembly 06, and the other part drives the rotation of the calibration and adjustment assembly 04. The rotation of the support rotary assembly 06 is primarily achieved using the rotational output of the rotary drive motor 51. To ensure that the rotary drive does not affect the angle adjustment of the support rotary assembly 06, a liquid level rotating ball joint is used for connection. Simultaneously, a positioning protrusion 521 is used for circumferential rotational positioning to prevent situations where the rotational position cannot be determined, thus avoiding inaccurate determination of the liquid level adjustment range.

[0073] The intake rotary drive mechanism 53 includes an actuating cylinder, a rotating sleeve 531, a compression spring 532, and a drive connecting rod 533. A sleeve hole is formed in the middle of the rotating sleeve 531. The rotating sleeve 531 is rotatably sleeved onto the rotary drive motor 51 through the sleeve hole. A drive hole is provided at the drive end of the rotating sleeve 531. The actuating rod of the actuating cylinder drives a supporting head. The driving supporting head is slidably disposed in the drive hole to achieve a motion connection between the actuating rod and the drive end. A driven hole is provided at the driven end of the rotating sleeve 531. One end of the drive connecting rod 533 is disposed in the driven hole, and the other end passes through an arc-shaped adjustment hole and is movably connected to the sealing grille. On the driven end, a supporting protrusion is provided on the side of the driven hole near the sleeve hole. One end of the compression spring 532 abuts against the supporting protrusion, and the other end abuts against the drive connecting rod 533.

[0074] The intake rotary drive mechanism 53 utilizes a linkage mechanism to achieve the rotational positioning of the sealing grille. Through the movement of the actuator cylinder and the rotation of the rotating sleeve 531, linear drive is converted into circular motion. Furthermore, the linear motion of the actuator cylinder ensures that the rotating sleeve 531 completes a semi-circular rotation to achieve angular adjustment of the supporting rotating component 06 across the entire circumference. Therefore, the size and position of the drive hole must be considered when creating it to achieve the semi-circular rotation of the rotating sleeve 531. Here, the drive linkage 533 only needs to connect to one of the sealing grilles; the other sealing grilles can achieve synchronous rotation under the drive of the elastic connector 43.

[0075] The maximum distance that the drive link 533 can reach in the driven hole is the maximum distance that the sealing gate can move against the adjusting disc 62 in its radial direction. It is necessary to consider that the size and position of the driven hole must meet the displacement requirements of the sealing gate to fully realize the angular adjustment of the supporting rotating assembly 06.

[0076] The supporting rotation assembly 06 includes a rotating base 61, an adjusting plate 62, an upper support rod 63, a covering sleeve 64, and an elastic body 65. A spherical connecting groove is provided on one end of the rotating base 61 near the rotating drive motor 51, and a positioning groove is provided on the groove wall along an axis perpendicular to the center of the sphere. The spherical connecting groove is fitted onto the liquid level rotating ball head 52, and the positioning groove slides in cooperation with the positioning protrusion 521 on the liquid level rotating ball head 52. A placement groove is provided on the placement plane of the rotating base 61 away from the rotating drive motor 51. The adjusting plate 62 is arranged around the side wall of the rotating base 61, and the adjusting plate 62 is angled to the placement plane. The upper support rod 63 is evenly spaced around the axis of the mounting base 01, with one end connected to the adjusting plate 62 and the other end connected to the covering sleeve 64. The elastic body 65 is spaced around the edge of the adjusting plate 62, and the end of the elastic body 65 away from the adjusting plate 62 is connected to the air intake ring wall.

[0077] The groove on the rotating support assembly 06 is used to fix the bottom of the measuring cylinder. It should be noted that, to improve adjustment accuracy, the groove and the bottom of the measuring cylinder are tightly fitted, preventing changes in the cylinder's tilt due to angle variations and thus avoiding adjustment failure. Of course, the corresponding cover sleeve 64 can also be a tight fit; for ease of removal, it can be a snap-on cover structure. The upper support rod 63 serves as an adjustable force-transmitting structure supporting the measuring cylinder during angle adjustment. To ensure adjustment accuracy, the upper support rod 63 needs to be evenly spaced around the central axis. The adjusting disc 62 primarily receives the resistance of the sealing grid and then transmits the adjustment force. The tilt of the adjusting disc 62 provides the structural basis for adjusting the resistance of the sealing grid.

[0078] The liquid level acquisition device 02 includes a vision acquisition unit and a moving column. The vision acquisition unit can move vertically along the moving column to collect liquid level data directly. The vision acquisition unit can be a camera, video camera, etc. Of course, to better achieve the automatic calibration function, the entire automatic calibration device can be centrally analyzed and controlled by a controller.

[0079] In summary, the beneficial effects of the automatic graduated cylinder calibration device and method for biomedicine provided in this application are as follows:

[0080] An automatic calibration method for graduated cylinders in the biopharmaceutical industry adjusts the verticality of the cylinder by using the effective value of the circumferential liquid level as the reference height for calibration. This allows for precise positioning of the angle requiring calibration. Furthermore, a reasonable liquid level data processing method improves the accuracy of data analysis. Simultaneous adjustment actions at different positions ensure the accuracy of automatic calibration. Additionally, utilizing air pressure as the power source for adjustment, a fluid-based adjustment method, matches changes in the solution level, achieving smooth and accurate adjustments.

[0081] An automatic graduated cylinder calibration device for biomedicine uses a supporting rotating assembly to hold the graduated cylinder containing the solution, and a level sensor to collect the solution level in the cylinder. A rotation drive assembly rotates the supporting rotating assembly, which in turn rotates the graduated cylinder, allowing the level sensor to obtain circumferential liquid level information when the cylinder is fixed in place, thus determining whether the liquid level is horizontal. The angle of the supporting rotating assembly is adjusted by the movement and inflation of the air inlet ring wall assembly and calibration adjustment assembly to ensure the graduated cylinder is vertical. This level calibration is performed every time the graduated cylinder is used to measure the solution, improving the accuracy of solution volume data acquisition and completely eliminating human error caused by placing the graduated cylinder on the supporting rotating assembly each time. Furthermore, using a level sensor to read the liquid level effectively avoids errors caused by human reading, further improving the accuracy of the graduated cylinder readings.

[0082] In this application, "at least one" means one or more, and "more than one" means two or more. "At least one of the following" or similar expressions refer to any combination of these items, including any combination of a single item or a plurality of items. For example, at least one of a, b, or c can mean: a, b, c, ab, ac, bc, or abc, where a, b, and c can be a single item or multiple items.

[0083] It should be understood that in the various embodiments of this application, the order of the above-mentioned processes does not imply the order of execution. The execution order of each process should be determined by its function and internal logic, and should not constitute any limitation on the implementation process of the embodiments of this application.

[0084] Those skilled in the art will recognize that the units and method steps of the various examples described in conjunction with the embodiments disclosed herein can be implemented in electronic hardware, or a combination of computer software and electronic hardware. Whether these functions are implemented in hardware or software depends on the specific application and design constraints of the technical solution. Those skilled in the art can use different methods to implement the described functions for each specific application, but such implementation should not be considered beyond the scope of this application.

[0085] Those skilled in the art will understand that, for the sake of convenience and brevity, the specific working processes of the systems, devices, and units described above can be referred to the corresponding processes in the foregoing method embodiments, and will not be repeated here.

[0086] In the several embodiments provided in this application, it should be understood that the disclosed systems, apparatuses, and methods can be implemented in other ways. For example, the apparatus embodiments described above are merely illustrative; for instance, the division of units is only a logical functional division, and in actual implementation, there may be other division methods. For example, multiple units or components may be combined or integrated into another system, or some features may be ignored or not executed. Furthermore, the coupling or direct coupling or communication connection shown or discussed may be through some interfaces; the indirect coupling or communication connection between apparatuses or units may be electrical, mechanical, or other forms.

[0087] The units described as separate components may or may not be physically separate. The components shown as units may or may not be physical units; that is, they may be located in one place or distributed across multiple network units. Some or all of the units can be selected to achieve the purpose of this embodiment according to actual needs.

[0088] In addition, the functional units in the various embodiments of this application can be integrated into one processing unit, or each unit can exist physically separately, or two or more units can be integrated into one unit.

[0089] If the aforementioned functions are implemented as software functional units and sold or used as independent products, they can be stored in a computer-readable storage medium. Based on this understanding, the technical solution of this application, in essence, or the part that contributes to the prior art, or a portion of the technical solution, can be embodied in the form of a software product. This computer software product is stored in a storage medium and includes several instructions to cause a computer device (which may be a personal computer, server, or network device, etc.) to execute all or part of the steps of the methods described in the various embodiments of this application. The aforementioned storage medium includes various media capable of storing program code, such as USB flash drives, portable hard drives, read-only memory (ROM), random access memory (RAM), magnetic disks, or optical disks.

[0090] The technical features of the above embodiments can be combined in any way. For the sake of brevity, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0091] The above embodiments merely illustrate several implementation methods of the present invention, and their descriptions are relatively specific and detailed, but they should not be construed as limiting the scope of the invention patent. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of the present invention, and these all fall within the protection scope of the present invention. Therefore, the protection scope of this invention patent should be determined by the appended claims.

Claims

1. A biomedical measuring cylinder automatic calibration method, characterized in that: include: Obtaining the liquid level heights at circumferential positions of the solution to be tested in the measuring cylinder to form circumferential liquid level height data; According to the circumferential liquid level height data, an inclination demarcation point analysis is performed to determine the inclination demarcation data; According to the tilt boundary data, analyzing the calibration displacement is performed to form target movement data; Performing calibration control according to the target movement data; Wherein, obtaining the liquid level height at the circumferential position of the solution to be tested in the measuring cylinder to form circumferential liquid level height data includes: Obtain the original liquid level height of the solution to be tested in the measuring cylinder at the circumferential position, and establish an original diagram of the angular displacement-height relationship; Smoothing the height data in the original angular displacement-height relationship graph to obtain a valid angular displacement-height relationship graph; According to the circumferential liquid level height data, an inclination demarcation point analysis is performed to determine the inclination demarcation data, including: Determine the average height H based on the angular displacement-height relationship effective diagram p , and the average height H p The corresponding two symmetrical angular displacement positions and ; Taking the two angular displacement positions as reference, determine the upper height extreme value H in the angular displacement-height relationship effective diagram max , lower height extreme value H min and the corresponding angular displacement position; According to the upper height extreme value H max , lower height extreme value H min and the average height H p , get the maximum inclination angle α: , where R is the effective liquid column radius; According to the tilt boundary data, the calibration displacement is analyzed to form the target movement data, including: Collect the initial placement inclination angle β, move the reference elevation H0, and obtain the target main moving distance S in combination with the maximum inclination angle α; Get the angular displacement difference between the auxiliary position and the main position , and establish the moving distance synchronization function y=F(x, ), where y∈[0, S], x represents the auxiliary moving distance parameter of the auxiliary position; Calibration control is performed according to the target movement data, including: Determine the main inflation rate P of the main position according to the target main movement distance S 主 ; According to the main inflation rate P 主 And the moving distance synchronization function y=F(x, ), determine the auxiliary inflation rate P of the auxiliary position 辅 ; According to the main inflation rate P 主 and the auxiliary inflation rate P 辅 Inflation control.

2. The biomedical measuring cylinder automatic calibration method according to claim 1, characterized in that: The smoothing of the height data in the original angular displacement-height relationship graph to obtain a valid angular displacement-height relationship graph comprises: Set the angular displacement step value k0, and the angular displacement step value obtains an odd number of angular displacements in the entire angular displacement. n The corresponding height parameter h n , where n is an odd natural number; Sequentially obtain the vector values ​​between two adjacent height parameters, perform matching analysis on the obtained vector values, and obtain the fitting relationship function F0 ( ); Set the angular displacement step change c and change threshold m; Taking the angular displacement step value as the starting step value, a step adjustment is performed for no less than the change threshold number of times, each adjustment step value obtained is formed by the last adjustment step value based on the angular displacement step change c, and a matching degree analysis is performed according to the adjustment step value, and an adjustment fitting relationship function F is obtained according to the analysis result. z ( ), where z≥m, z represents the actual number of times the angular displacement step value changes; Comprehensive fitting relationship function F0 ( ) and the adjusted fitting relationship function F z ( ), obtain the effective diagram of the angular displacement-height relationship.

3. The biomedical measuring cylinder automatic calibration method according to claim 2, characterized in that: Perform matching analysis on the obtained vector value, and obtain the fitting relationship function F0 ( ) and performing matching analysis according to the adjustment step value, and obtaining the adjustment fitting relationship function F according to the analysis result z ( ), including the following analysis: When the acquired vector values ​​are matched and equal in pairs, function fitting is performed according to the vector values; When the obtained vector values ​​are not equal at the symmetrical angular displacement positions, then: Setting an adjustment variable, and synchronously adjusting the angular displacement at a symmetrical position based on the adjustment variable, wherein the adjusted angular displacement is between adjacent initial angular displacement values; The vector values ​​are obtained according to the adjusted height values ​​until the obtained vector values ​​form a pairwise matching result; Function fitting is performed based on the adjusted matching result data.

4. The biomedical measuring cylinder automatic calibration method according to claim 2, characterized in that: The comprehensive fitting relationship function F0 ( ) and the adjusted fitting relationship function F z ( ), obtaining the effective graph of the angular displacement-height relationship, including: For the fitting relationship function F0 ( ) and the adjusted fitting relationship function F z ( ) to calculate the angular displacement-height relationship function F ( ): F( )=(F0( )+ΣF z ( )) / (z+1); According to the angular displacement-height relationship function F ( ) to form the angular displacement-height relationship diagram.

5. The biomedical measuring cylinder automatic calibration method according to claim 1, characterized in that: The target main moving distance S is obtained by the following formula: 。 6. An automatic calibration device for a biomedical measuring cylinder, using the automatic calibration method for a biomedical measuring cylinder according to any one of claims 1 to 5, characterized in that: It comprises a mounting base, a liquid level collector, an air intake ring wall assembly, a calibration adjustment assembly, a rotation drive assembly and a support rotation assembly; the mounting base is provided with a mounting groove; the rotation drive assembly is arranged in the mounting groove; the support rotation assembly is rotationally connected with the rotation drive assembly, and the support rotation assembly is located on the mounting base; the air intake ring wall assembly is arranged on the mounting base around the support rotation assembly; the calibration adjustment assembly is arranged on the mounting base around the support rotation assembly, and the calibration adjustment assembly abuts against the support rotation assembly; The calibration adjustment component is rotatably connected to the rotary drive component; an adjustment air inlet cavity is provided on the calibration adjustment component, and the adjustment air inlet cavity is connected to the air inlet ring wall; the liquid level collector is provided on the mounting base, and the liquid level collector is located at the periphery of the air inlet ring wall component; The rotary drive assembly controls the rotation of the supporting rotating assembly, the liquid level collector collects the liquid level information of the measuring cylinder on the supporting rotating assembly, and controls the rotation and positioning of the calibration adjustment assembly according to the liquid level information; the air intake ring wall assembly controls the calibration of the supporting rotating assembly by intake air into the adjustment air intake cavity.

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