A learning sperm screening identifier
The learning sperm screening device addresses the issue of reactive oxygen species damage by incorporating an antioxidant system and image recognition, enhancing sperm quality and screening efficiency for assisted reproductive technology.
Patent Information
- Application Number
- CN202410724025.X
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2024-06-05
- Publication Date
- 2024-12-10
- Estimated Expiration
- 2044-06-05
AI Technical Summary
Existing sperm screening devices do not effectively reduce the harmful effects of reactive oxygen species on sperm during the upstream process, which can damage sperm DNA and membrane structure, affecting fertilization ability.
A learning sperm screening and identification device that includes a temperature-controlled environment with an antioxidant system to neutralize reactive oxygen species, combined with an image recognition module for automated sperm quality assessment.
The device effectively neutralizes reactive oxygen species and automates the selection of high-quality sperm, reducing damage and improving the efficiency of sperm screening for assisted reproductive technology.
Smart Images

Figure CN118703319B_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of sperm screening, and in particular to a learning type sperm screening identifier. Background Art
[0002] The Chinese utility model patent with the publication number CN211445700U discloses a sperm screening device, which includes a box body, a box cover is provided at the upper end of the box body, a vertically slidable support plate is provided in the box body, vertical plates are provided on both the left and right sides of the support plate, a plurality of semen tanks are provided on the support plate, a semen outlet is provided on the side wall of the support plate, a sealing ring is provided at the semen outlet, and the bottom ends of the semen tanks are connected to the semen outlet through pipes; an opening with the same diameter as the semen outlet is provided on the side wall of the box body, and when the support plate moves to the bottom inner side of the box body, the semen outlet is aligned with the opening; the opening is connected to an inclined sperm swimming tube, and the top of the sperm swimming tube is connected to a collection box, and the upper and lower ends of the collection box are respectively provided with an inlet and an outlet, and a valve I is provided at the outlet. It has the characteristics of heat preservation, convenient start and stop, and simulated sperm swimming environment.
[0003] However, during the sperm's upstream process, the sperm itself will carry out metabolic activities and produce a certain amount of reactive oxygen species. Reactive oxygen species are by-products of cell metabolism. Excessive reactive oxygen species may cause damage to the sperm, including damage to the sperm's DNA, membrane structure and function, thereby affecting the sperm's quality and fertilization ability. The above-mentioned patent does not have the function of reducing the content of reactive oxygen in the sperm's upstream environment. Summary of the invention
[0004] In view of the above technical problems, the present invention aims to provide a learning sperm screening identifier. To solve the above technical problems, the present invention adopts the following technical solutions:
[0005] A learning sperm screening and identification device comprises a base, a screening seat, a mounting plate, a fixing tube, an elastic tube 1, a sliding tube and an image recognition device, the screening seat and the mounting plate are both fixedly connected to the top wall of the base, a temperature sensor and a processing module are fixedly connected in the screening seat, a box cavity and a hot water cavity are provided on the screening seat, the side wall of the box cavity is connected to the outer wall of the screening seat through a connecting channel, a sperm storage box is slidably connected to the inner wall of the box cavity, a sperm storage cavity is provided on the sperm storage box, the bottom wall of the sperm storage cavity is in an inclined shape, the sperm storage cavity is connected to the outer wall of the sperm storage box through an inclined sperm outlet channel 1, the hot water cavity is filled with a water source, a heater is fixedly connected in the screening seat, a heating rod is fixedly connected to the heater, and one end of the heating rod extends to the water source in the hot water cavity;
[0006] The fixed tube is fixedly connected to the outer wall of the screening seat, the fixed tube is communicated with the connecting channel, the elastic tube 1 is fixedly connected to the fixed tube, the sliding tube is fixedly connected to the elastic tube 1, the sliding tube is slidably connected to the mounting plate, the image recognition device is fixedly connected to the top wall of the sliding tube, the mounting plate is connected with an antioxidant adding component, the antioxidant adding component is connected to the sliding tube, and the material of the sliding tube includes a transparent material.
[0007] Furthermore, the antioxidant adding component includes a thermal expansion member, an antioxidant box, a bent rod, a transmission plate, a transmission rod and a rack. The thermal expansion member is fixedly connected to the heating rod, and the right end of the thermal expansion member extends to the outside of the screening seat. The antioxidant box is fixedly connected to the mounting plate. The antioxidant box is provided with a liquid suction chamber, a liquid storage chamber and a rod chamber. The inner wall of the liquid suction chamber is slidably connected to a piston, and a linkage rod is fixedly connected to the piston. The left end of the linkage rod extends to the outside of the antioxidant box. The left end of the linkage rod is fixedly connected to a pressing plate, and the pressing plate is connected to the outer wall of the antioxidant box through an elastic member. The pressing plate and the right end of the thermal expansion member are fixedly connected. The bottom wall of the liquid suction chamber is fixedly connected to a liquid extraction pipe and a liquid outlet pipe. The lower end of the liquid extraction pipe extends into the liquid storage chamber. The liquid storage chamber is filled with antioxidants. A one-way valve is fixedly connected to the liquid extraction pipe. A one-way valve is fixedly connected to the liquid outlet pipe, and an elastic tube is fixedly connected to the lower end of the liquid outlet pipe. The elastic tube is fixedly connected to the top wall of the sliding tube. The bent rod is slidably connected to the inner wall of the rod cavity. One end of the bent rod is fixedly connected to the transmission plate. The bent rod extends into the liquid suction cavity. The transmission plate is located outside the antioxidant box. A transmission channel is opened on the transmission plate. The transmission channel is inclined. The transmission rod is slidably connected to the mounting plate. A transmission convex strip is rotatably connected to the transmission rod. The transmission convex strip is slidably connected to the inner wall of the transmission channel. A mounting seat is fixedly connected to the transmission rod, and a connecting piece is fixedly connected to the mounting seat. The connecting piece is fixedly connected to the limit block through the elastic member 2. The limit block is slidably connected to the mounting seat. A limiting tooth is fixedly connected to the limit block. The limiting tooth is inserted between two of the saw teeth on the rack, and the rack is fixedly connected to the mounting plate.
[0008] Furthermore, a transmission groove is provided on the screening seat, and a movable plate is slidably connected to the inner wall of the transmission groove, and a sperm screening membrane is detachably connected to the movable plate. The transmission groove is connected to the sliding tube through a plate channel, and the movable plate extends into the plate channel. An extension rod is fixedly connected to the bottom wall of the movable plate, and the extension rod is fixedly connected to the bottom wall of the transmission groove through elastic member three. A slide plate is slidably connected to the mounting plate, and the extension rod extends above the slide plate. The bottom wall of the extension rod is fixedly connected to the top wall of the slide plate through elastic member four, and a top plate is slidably connected to the mounting seat.
[0009] Furthermore, a pressing piece is fixedly connected to the limit block.
[0010] Furthermore, a first slide rail is fixedly connected to the mounting seat, the limit block and the top plate are both slidably connected to the first slide rail, a second slide rail is fixedly connected to the mounting plate, and the slide plate is slidably connected to the second slide rail.
[0011] Furthermore, a handle is fixedly connected to the top wall of the sperm storage box.
[0012] Furthermore, the inner wall of the sliding tube is fixedly connected with two or more partitions, and the partitions divide the inner cavity of the sliding tube into two or more identification cavities.
[0013] Furthermore, the bottom wall of the sliding tube is fixedly connected with two or more valves.
[0014] Furthermore, the image recognition device is provided with an image acquisition module and an image recognition module, the image acquisition module acquires the original image, and the image recognition module recognizes the original image.
[0015] Furthermore, the recognition step of the image recognition module includes:
[0016] Step 1: preprocessing the original image to obtain a processed image;
[0017] Step 2: Compare the processed image with the images in the sperm image library to obtain the defect recognition result.
[0018] The present invention has the following beneficial effects:
[0019] The antioxidant box of the present invention can automatically add antioxidants to the fixed tube, the elastic tube and the sliding tube to neutralize active oxygen and reduce the damage of active oxygen to sperm. BRIEF DESCRIPTION OF THE DRAWINGS
[0020] The present invention is further described using the accompanying drawings, but the embodiments in the accompanying drawings do not constitute any limitation to the present invention. A person skilled in the art can obtain other drawings based on the following drawings without creative work.
[0021] Figure 1 It is a structural schematic diagram of a learning sperm screening and identification device of the present invention;
[0022] Figure 2 The present invention Figure 1 Schematic diagram of the structure of the middle sliding tube;
[0023] Figure 3 The present invention Figure 1 The enlarged view of point A in the middle;
[0024] Figure 4 The present invention Figure 1 The enlarged view of point B in the middle;
[0025] Figure 5 The present invention Figure 1 Enlarged view of point C in the middle;
[0026] Figure 6 The present invention Figure 1 Enlarged view of point D in the middle.
[0027] Figure numerals: 1, base; 2, screening seat; 3, mounting plate; 4, box cavity; 5, sperm storage box; 6, sperm storage cavity; 7, sperm outlet channel 1; 8, pull handle; 9, connecting channel; 10, hot water cavity; 11, heater; 12, heating rod; 13, thermal expansion member; 14, pressing sheet; 141, elastic member 1; 15, linkage rod; 16, liquid suction cavity; 17, piston; 18, antioxidant box; 19, liquid storage cavity; 20, liquid extraction tube; 21, one-way valve 1; 22, liquid outlet tube; 23, one-way valve 2; 24, elastic tube 2; 25, bending rod; 251, rod cavity; 26, transmission plate; 27, Transmission channel; 28. Transmission rod; 29. Transmission convex strip; 30. Mounting seat; 31. Limit block; 32. Limit tooth; 33. Press plate; 34. Elastic member 2; 35. Connecting plate; 36. Top plate; 37. Slide rail 1; 38. Slide plate; 39. Extension rod; 40. Movable plate; 41. Sperm screening membrane; 42. Elastic member 3; 43. Transmission groove; 44. Plate channel; 45. Valve; 46. Rack; 47. Fixed tube; 48. Elastic tube 1; 49. Sliding tube; 50. Image recognition device; 51. Recognition chamber; 52. Partition; 53. Slide rail 2; 54. Elastic member 4. DETAILED DESCRIPTION
[0028] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0029] In the description of the present invention, it should be noted that the terms "vertical", "upper", "lower", "horizontal", etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, "first", "second", "third", and "fourth" are only used for descriptive purposes and cannot be understood as indicating or implying relative importance.
[0030] In the description of the present invention, it is also necessary to explain that, unless otherwise clearly specified and limited, the terms "set", "install", "connect", and "connect" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection, it can be a mechanical connection, it can be an electrical connection, it can be a direct connection, it can be connected through an intermediate medium, and it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.
[0031] like Figure 1-Figure 6 As shown, a learning sperm screening and identification device includes a base 1, a screening seat 2, a mounting plate 3, a fixed tube 47, an elastic tube 48, a sliding tube 49 and an image recognition device 50. The screening seat 2 and the mounting plate 3 are both fixedly connected to the top wall of the base 1. The screening seat 2 is fixedly connected with a temperature sensor and a processing module. The screening seat 2 is provided with a box cavity 4 and a hot water cavity 10. The side wall of the box cavity 4 is connected to the outer wall of the screening seat 2 through a connecting channel 9. The inner wall of the box cavity 4 is slidably connected with a sperm storage box 5. The sperm storage box 5 is provided with a sperm storage cavity 6. The bottom wall of the sperm storage cavity 6 is inclined. The sperm storage cavity 6 is connected to the outer wall of the screening seat 2 through a connecting channel 9. The inclined sperm outlet channel 7 is connected to the outer wall of the sperm storage box 5, the hot water chamber 10 is filled with water, a heater 11 is fixedly connected to the screening seat 2, a heating rod 12 is fixedly connected to the heater 11, one end of the heating rod 12 extends to the water source in the hot water chamber 10, and the heating rod 12 can be heated when the heater 11 is powered on, thereby heating the water source to maintain the sperm at about 37 degrees, which is close to the human body temperature. The screening seat 2 and the sperm storage box 5 can be made of materials with good thermal conductivity, and the temperature sensor can be installed in a suitable position, such as the inner wall of the connecting channel 9 and the inner wall of the box chamber 4;
[0032] The fixed tube 47 is fixedly connected to the outer wall of the screening seat 2, the fixed tube 47 is connected to the connecting channel 9, the elastic tube 48 is fixedly connected to the fixed tube 47, the sliding tube 49 is fixedly connected to the elastic tube 48, the sliding tube 49 is slidably connected to the mounting plate 3, the image recognition device 50 is fixedly connected to the top wall of the sliding tube 49, and the mounting plate 3 is connected with an antioxidant adding component, the antioxidant adding component is connected to the sliding tube 49, the antioxidant adding component can add antioxidants to the sliding tube 49, and the material of the sliding tube 49 includes a transparent material, and the transparent material can be glass.
[0033] According to an optional embodiment of the present invention, the antioxidant adding component includes a heat expansion member 13, an antioxidant box 18, a bent rod 25, a transmission plate 26, a transmission rod 28 and a rack 46, the heat expansion member 13 is fixedly connected to the heating rod 12, the right end of the heat expansion member 13 extends to the outside of the screening seat 2, the antioxidant box 18 is fixedly connected to the mounting plate 3, and the antioxidant box 18 is provided with a liquid suction chamber 16, a liquid storage chamber 19 and a rod chamber 251, the inner wall of the liquid suction chamber 16 is slidably connected to a piston 17, and the piston 17 is fixed A linkage rod 15 is connected, the left end of the linkage rod 15 extends to the outside of the antioxidant box 18, the left end of the linkage rod 15 is fixedly connected to a pressing sheet 14, the pressing sheet 14 is connected to the outer wall of the antioxidant box 18 through an elastic member 141, the pressing sheet 14 is fixedly connected to the right end of the heat expansion member 13, the bottom wall of the liquid suction chamber 16 is fixedly connected to a liquid extraction tube 20 and a liquid outlet tube 22, the lower end of the liquid extraction tube 20 extends to the liquid storage chamber 19, and the liquid storage chamber 19 is filled with an antioxidant, which can be vitamin C, vitamin E, coenzyme Q10, selenium, zinc, etc., and the neutralization fixed tube 47, the elastic The one-way valve 21 is fixedly connected to the liquid extraction tube 20, the one-way valve 23 is fixedly connected to the liquid outlet tube 22, the lower end of the liquid outlet tube 22 is fixedly connected to the elastic tube 24, the elastic tube 24 is fixedly connected to the top wall of the sliding tube 49, the curved rod 25 is slidably connected to the inner wall of the rod cavity 251, one end of the curved rod 25 is fixedly connected to the transmission plate 26, the curved rod 25 extends into the liquid suction cavity 16, the transmission plate 26 is located outside the antioxidant box 18, and a transmission channel 27 is opened on the transmission plate 26, and the transmission channel 27 is inclined. The transmission rod 28 is slidably connected to the mounting plate 3, and a transmission convex strip 29 is rotatably connected to the transmission rod 28. The transmission convex strip 29 is slidably connected to the inner wall of the transmission channel 27. A mounting seat 30 is fixedly connected to the transmission rod 28, and a connecting piece 35 is fixedly connected to the mounting seat 30. The connecting piece 35 is fixedly connected to the limit block 31 through the elastic member 2 34. The limit block 31 is slidably connected to the mounting seat 30. A limit tooth 32 is fixedly connected to the limit block 31. The limit tooth 32 is inserted between two of the serrations on the rack 46. The rack 46 is fixedly connected to the mounting plate 3.
[0034] According to an optional embodiment of the present invention, a transmission groove 43 is provided on the screening seat 2, and a movable plate 40 is slidably connected to the inner wall of the transmission groove 43, and a sperm screening mesh 41 is detachably connected to the movable plate 40. The sperm screening mesh 41 is a component used in assisted reproductive technology. The sperm screening mesh 41 usually has a specific aperture size, which allows only sperm with strong vitality and normal morphology to pass through, while screening out sperm with weak vitality or abnormal morphology. The transmission groove 43 is connected to the sliding tube 49 through a plate channel 44, and the movable plate 40 extends into the plate channel 44. An extension rod 39 is fixedly connected to the bottom wall of the movable plate 40, and the extension rod 39 is fixedly connected to the bottom wall of the transmission groove 43 through an elastic member three 42. A slide plate 38 is slidably connected to the mounting plate 3, and the extension rod 39 extends to the top of the slide plate 38. The bottom wall of the extension rod 39 is fixedly connected to the top wall of the slide plate 38 through an elastic member four 54. A top plate 36 is slidably connected to the mounting seat 30.
[0035] According to an optional implementation of the present invention, a pressing piece 33 is fixedly connected to the limiting block 31 .
[0036] According to an optional embodiment of the present invention, a slide rail 37 is fixedly connected to the mounting seat 30, the limit block 31 and the top plate 36 are slidably connected to the slide rail 37, a slide rail 53 is fixedly connected to the mounting plate 3, and the slide plate 38 is slidably connected to the slide rail 53.
[0037] According to an optional embodiment of the present invention, a handle 8 is fixedly connected to the top wall of the sperm storage box 5 to facilitate the user to control the lifting and lowering of the sperm storage box 5.
[0038] According to an optional embodiment of the present invention, two or more partitions 52 are fixedly connected to the inner wall of the sliding tube 49 , and the partitions 52 divide the inner cavity of the sliding tube 49 into two or more identification cavities 51 .
[0039] According to an optional implementation of the present invention, two or more valves 45 are fixedly connected to the bottom wall of the sliding tube 49 .
[0040] According to an optional implementation of the present invention, the image recognition device 50 is provided with an image acquisition module and an image recognition module, the image acquisition module acquires the original image, and the image recognition module recognizes the original image.
[0041] According to an optional implementation of the present invention, the recognition step of the image recognition module includes:
[0042] Step 1: preprocessing the original image to obtain a processed image, wherein the preprocessing may be noise reduction processing;
[0043] Step 2: Compare the processed image with the images in the sperm image library to obtain the defect recognition result. The defect recognition result includes the ratio of the number of normal sperm to the number of defective sperm in a certain area. The larger the ratio of the number of normal sperm to the number of defective sperm in a certain area, the better the overall quality of sperm in the area.
[0044] In traditional ART assisted reproductive technology operations, ICSI intracytoplasmic sperm injection (ICSI) is often performed by identifying feasible sperm with the naked eye. Due to the clarity and rapid operation of ICSI instruments, it is sometimes impossible to select excellent sperm for ICSI. This embodiment has a learning function, through which a large amount of image materials are accumulated in the image library, the required sperm is identified from the processed images, the sperm with problems is excluded, and the sperm with better quality is selected. The image recognition module runs dynamically, and the materials in the image library can be increased and decreased at any time, so as to identify sperm of different forms, identify them in time, and not delay the selection of sperm, and finally reduce the time for selecting high-quality sperm, so that excellent sperm can be selected in a very short time for ICSI intracytoplasmic sperm injection operation to obtain excellent embryos.
[0045] Implementation process: In the initial state, the sperm storage box 5 is located above the connecting channel 9, the sperm outlet channel 7 and the connecting channel 9 are not connected, the sperm screening membrane 41 is located in the plate channel 44, the top plate 36 is located at the lower right of the slide plate 38, and the top plate 36 will not collide with the slide plate 38 when moving up, and the limiting tooth 32 is inserted between two serrations on the rack 46 for limiting.
[0046] When sperm selection is required, the sperm storage chamber 6 is filled with semen, the connecting channel 9, the fixed tube 47, the elastic tube 48, and the sliding tube 49 are filled with upstream liquid, the pull handle 8 is controlled to lower the sperm storage box 5, the sperm outlet channel 7 is connected to the connecting channel 9, the heater 11 is energized to heat the heating rod 12, and the heating rod 12 heats the water source in the hot water chamber 10. When the temperature sensor detects that the temperature is equal to 37 degrees, the processing module controls the heater 11 to stop heating. When the temperature sensor detects that the temperature is lower than 36 degrees, the processing module The heater 11 is powered on, and the heating rod 12 heats the water source again, so that the sperm is within the normal temperature range of the human body, thereby simulating the human body environment. Two fingers pinch the connecting piece 35 and the pressing piece 33, so that the limit block 31 overcomes the elastic force of the elastic piece 34 and moves to the left. The limit block 31 pushes the top piece 36 to move left to below the slide plate 38, and the limit tooth 32 is separated from the rack 46. The transmission rod 28 is controlled to rise and fall, so that the sliding tube 49 rises and falls, and the elastic tube 48 has an inclined angle, thereby simulating the inclined and tortuous loop in the human uterus and vas deferens. The environment is formed, and the sperm with strong vitality is screened out. Two fingers loosen the connecting piece 35 and the pressing piece 33. The limit block 31 and the limit tooth 32 are reset to the right under the elastic force of the elastic member 34. The limit tooth 32 is inserted between the other two saw teeth on the rack 46 to complete the limit, preventing the transmission rod 28 from moving up and down. When the top plate 36 moves up, it will push the slide plate 38, the extension rod 39, the movable plate 40, and the sperm screening mesh 41 to move up, so that the sperm screening mesh 41 and the top wall of the connecting channel 9 are against each other, and the sperm screening mesh 41 can perform the first screening. Sperm with strong force and normal morphology can pass through the sperm screening omentum 41, and then some sperm overcome gravity and do work in the upstream liquid of the fixed tube 47 and the elastic tube 48, and swim upstream to the sliding tube 49 to complete the second screening. The sperm swims to different identification cavities 51, and the defect recognition result is obtained through the recognition of the image recognition device 50. According to the defect recognition result, the appropriate valve 45 is selected to open, so that the upstream liquid and sperm in a certain identification cavity 51 are transferred to an external storage container, completing the third screening, and then proceeding with subsequent operations.
[0047] In some cases, for example, if the number of sperm in the upstream sliding tube 49 needs to be increased, and the screening of the sperm screening membrane 41 is not required, when the moving plate 33 moves to the left, the top plate 36 does not need to be pushed under the slide plate 38, that is, the leftward movement distance of the limit block 31 becomes smaller.
[0048] When sperm overcomes gravity and works upstream in the elastic tube 48, active oxygen is generated. When the heating rod 12 is heated, the thermal expansion member 13 expands. After the heating rod 12 stops heating, the thermal expansion member 13 shrinks, thereby causing the pressing plate 14, the linkage rod 15, and the piston 17 to move back and forth left and right. When the piston 17 moves to the left, under the action of pressure, the one-way valve 21 opens and the one-way valve 23 closes, and the liquid extraction tube 20 absorbs the antioxidant in the liquid storage chamber 19 into the liquid suction chamber 16, so that the liquid suction chamber 16 is filled with the antioxidant. When the piston 17 moves to the right, the one-way valve 21 closes and the one-way valve 23 opens, and the piston 17 pushes the antioxidant in the liquid suction chamber 16 through the one-way valve 23 into the liquid outlet pipe 22, the elastic tube 24, and then into the sliding tube 49, the elastic tube 1 48, and the fixed tube 47, thereby neutralizing the active oxygen and reducing the damage of the active oxygen to the sperm.
[0049] When the transmission rod 28 moves up to a higher height, the transmission convex strip 29 pushes the transmission plate 26 and the bent rod 25 to move leftward through the transmission channel 27. The more the bent rod 25 is positioned to the left, the more the left limit position of the piston 17 moves to the left after the heat expansion member 13 contracts, the right limit position of the piston 17 is fixed, the larger the stroke of each reciprocating motion of the piston 17, the more the amount of antioxidant absorbed and pushed out of the suction chamber 16 at one time, on the contrary, when the transmission rod 28 moves up to a lower height, the more the bent rod 25 is positioned to the right, the more the left limit position of the piston 17 moves to the left, the right limit position of the piston 17 is fixed, the smaller the stroke of each reciprocating motion of the piston 17, the less the amount of antioxidant absorbed and pushed out of the suction chamber 16 at one time, which meets the requirement that when the inclination of the elastic tube 48 is greater, the more active oxygen generated by the sperm swimming is, and more antioxidants are needed for neutralization, thereby realizing that the antioxidant box 18 automatically adjusts the amount of antioxidant pushed out each time according to the inclination of the elastic tube 48.
[0050] The reset of the device can refer to the above principle and just move some parts in the reverse direction, which will not be described again here.
[0051] The antioxidant box 18 of the present invention can automatically add antioxidants to the fixed tube 47, the elastic tube 48, and the sliding tube 49 to neutralize the active oxygen and reduce the damage of the active oxygen to the sperm. The antioxidant box 18 can also automatically adjust the amount of antioxidant introduced each time according to the inclination of the elastic tube 48 to prevent excessive or insufficient antioxidants from causing waste and affecting the sperm. The three-pass screening of sperm is achieved through the sperm screening membrane 41, the inclined elastic tube 48 and the image recognition device 50, so that better quality sperm can be screened out for subsequent ICSI intracytoplasmic sperm injection operations.
[0052] The components, modules, mechanisms and devices not described in detail in the present invention are all universal standard parts or components known to those skilled in the art, and their structures and principles can be known to those skilled in the art through technical manuals or conventional experimental methods.
[0053] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the present invention, rather than to limit the scope of protection of the present invention. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solution of the present invention can be modified or replaced by equivalents without departing from the essence and scope of the technical solution of the present invention.
Claims
1. A learning sperm screening identifier, characterized in that: The invention comprises a base (1), a screening seat (2), a mounting plate (3), a fixing tube (47), an elastic tube (48), a sliding tube (49) and an image recognition device (50); the screening seat (2) and the mounting plate (3) are both fixedly connected to the top wall of the base (1); a temperature sensor and a processing module are fixedly connected inside the screening seat (2); a box cavity (4) and a hot water cavity (10) are formed on the screening seat (2); and a side wall of the box cavity (4) is connected to an outer wall of the screening seat (2) through a connecting channel (9). The inner wall of the box cavity (4) is slidably connected to a sperm storage box (5), a sperm storage chamber (6) is provided on the sperm storage box (5), the bottom wall of the sperm storage chamber (6) is in an inclined shape, the sperm storage chamber (6) is connected to the outer wall of the sperm storage box (5) through an inclined sperm outlet channel (7), the hot water cavity (10) is filled with a water source, a heater (11) is fixedly connected to the screening seat (2), a heating rod (12) is fixedly connected to the heater (11), and one end of the heating rod (12) extends into the water source in the hot water cavity (10); The fixed tube (47) is fixedly connected to the outer wall of the screening seat (2), the fixed tube (47) is communicated with the connecting channel (9), the elastic tube (48) is fixedly connected to the fixed tube (47), the sliding tube (49) is fixedly connected to the elastic tube (48), the sliding tube (49) is slidably connected to the mounting plate (3), the image recognition device (50) is fixedly connected to the top wall of the sliding tube (49), the mounting plate (3) is connected to an antioxidant adding component, the antioxidant adding component is connected to the sliding tube (49), and the material of the sliding tube (49) includes a transparent material; The antioxidant adding assembly comprises a heat expansion member (13), an antioxidant box (18), a bent rod (25), a transmission plate (26), a transmission rod (28) and a rack (46); the heat expansion member (13) is fixedly connected to the heating rod (12); the right end of the heat expansion member (13) extends to the outside of the screening seat (2); the antioxidant box (18) is fixedly connected to the mounting plate (3); a liquid suction chamber (16), a liquid storage chamber (19) and a rod chamber (251) are provided on the antioxidant box (18); a piston (17) is slidably connected to the inner wall of the liquid suction chamber (16); the piston (17) A linkage rod (15) is fixedly connected to the upper part, the left end of the linkage rod (15) extends to the outside of the antioxidant box (18), the left end of the linkage rod (15) is fixedly connected to a pressing plate (14), the pressing plate (14) is connected to the outer wall of the antioxidant box (18) through an elastic member (141), the right end of the pressing plate (14) and the heat expansion member (13) are fixedly connected, the bottom wall of the liquid suction chamber (16) is fixedly connected to a liquid extraction pipe (20) and a liquid outlet pipe (22), the lower end of the liquid extraction pipe (20) extends to the liquid storage chamber (19), the liquid storage chamber (19) is filled with an antioxidant, a one-way valve (21) is fixedly connected to the liquid extraction pipe (20), and the liquid outlet pipe (22) is fixedly connected to the bottom wall of the liquid suction chamber (16). A check valve (23) is fixedly connected to the top of the liquid outlet pipe (22), an elastic tube (24) is fixedly connected to the lower end of the liquid outlet pipe (22), the elastic tube (24) is fixedly connected to the top wall of the sliding tube (49), the bent rod (25) is slidably connected to the inner wall of the rod cavity (251), one end of the bent rod (25) is fixedly connected to the transmission plate (26), the bent rod (25) extends into the liquid suction cavity (16), the transmission plate (26) is located outside the antioxidant box (18), a transmission channel (27) is opened on the transmission plate (26), the transmission channel (27) is inclined, the transmission rod (28) is slidably connected to the mounting plate (3), and the transmission A transmission convex strip (29) is rotatably connected to the rod (28), the transmission convex strip (29) is slidably connected to the inner wall of the transmission channel (27), a mounting seat (30) is fixedly connected to the transmission rod (28), a connecting piece (35) is fixedly connected to the mounting seat (30), the connecting piece (35) is fixedly connected to the limiting block (31) through a second elastic member (34), the limiting block (31) is slidably connected to the mounting seat (30), a limiting tooth (32) is fixedly connected to the limiting block (31), the limiting tooth (32) is inserted between two saw teeth on the rack (46), and the rack (46) is fixedly connected to the mounting plate (3); When sperm overcomes gravity and works upstream in the elastic tube 1 (48), active oxygen is generated. When the heating rod (12) is heated, the heat expansion member (13) expands. After the heating rod (12) stops heating, the heat expansion member (13) contracts, thereby causing the pressing plate (14), the linkage rod (15), and the piston (17) to reciprocate left and right. When the piston (17) moves left, under the action of pressure, the one-way valve 1 (21) opens, the one-way valve 2 (23) closes, and the liquid extraction tube (20) is closed. The antioxidant in the liquid storage chamber (19) is absorbed into the liquid suction chamber (16), so that the liquid suction chamber (16) is filled with the antioxidant. When the piston (17) moves to the right, the one-way valve (21) is closed and the one-way valve (23) is opened. The piston (17) pushes the antioxidant in the liquid suction chamber (16) through the one-way valve (23) into the liquid outlet pipe (22), the elastic pipe (24), and then into the sliding pipe (49), the elastic pipe (48), and the fixed pipe (47).
2. A learning sperm screening and identification device according to claim 1, characterized in that: The screening seat (2) is provided with a transmission groove (43), the inner wall of the transmission groove (43) is slidably connected to a movable plate (40), the movable plate (40) is detachably connected to a sperm screening mesh (41), the transmission groove (43) is communicated with the sliding tube (49) through a plate channel (44), the movable plate (40) extends into the plate channel (44), an extension rod (39) is fixedly connected to the bottom wall of the movable plate (40), the extension rod (39) is fixedly connected to the bottom wall of the transmission groove (43) through an elastic member three (42), a slide plate (38) is slidably connected to the mounting plate (3), the extension rod (39) extends to the top of the slide plate (38), the bottom wall of the extension rod (39) is fixedly connected to the top wall of the slide plate (38) through an elastic member four (54), and a top plate (36) is slidably connected to the mounting seat (30).
3. A learning sperm screening and identification device according to claim 2, characterized in that: A pressing piece (33) is fixedly connected to the limiting block (31).
4. A learning sperm screening and identification device according to claim 3, characterized in that: The mounting seat (30) is fixedly connected to a first slide rail (37), the limit block (31) and the top plate (36) are both slidably connected to the first slide rail (37), the mounting plate (3) is fixedly connected to a second slide rail (53), and the slide plate (38) is slidably connected to the second slide rail (53).
5. A learning sperm screening and identification device according to claim 4, characterized in that: A handle (8) is fixedly connected to the top wall of the sperm storage box (5).
6. A learning sperm screening and identification device according to any one of claims 1 to 5, characterized in that: The inner wall of the sliding tube (49) is fixedly connected to two or more partitions (52), and the partitions (52) divide the inner cavity of the sliding tube (49) into two or more identification cavities (51).
7. A learning sperm screening and identification device according to claim 6, characterized in that: The bottom wall of the sliding tube (49) is fixedly connected to two or more valves (45).
8. A learning sperm screening and identification device according to claim 7, characterized in that: The image recognition device (50) is provided with an image acquisition module and an image recognition module, wherein the image acquisition module acquires the original image and the image recognition module recognizes the original image.
9. A learning sperm screening and identification device according to claim 8, characterized in that: The recognition step of the image recognition module includes: Step 1: preprocessing the original image to obtain a processed image; Step 2: Compare the processed image with the images in the sperm image library to obtain the defect recognition result.
