A biomedical suspended matter separation device and separation method

Abstract

The present invention discloses a biomedical suspended matter separation device and separation method, the device comprises a box body, a partition is vertically arranged on one side of the interior of the box body, a fixed frame is arranged in the box body, fixed shafts are fixedly connected to both sides of the fixed frame, one end of one fixed shaft is rotatably connected to the inner wall of the box body, one end of the other fixed shaft is rotatably connected to the partition, a moving frame is slidably connected to the surface of the fixed frame, a first actuator for pushing the moving frame to slide is arranged in the fixed frame, a bottom filter cartridge is fixedly connected to the bottom of the inner wall of the moving frame, a plurality of bottom filter cartridges are arranged, a middle filter cartridge is arranged above the bottom filter cartridge, and a top filter cartridge is arranged above the middle filter cartridge, the present invention relates to the field of suspended matter separation technology. This biomedical suspended matter separation device and separation method adopts an innovative design of setting a multi-layer membrane for step-by-step separation, aiming to solve the problems existing in the prior art and improve separation efficiency and operation convenience.

Description

Technical Field

[0001] The present invention relates to the technical field of suspended matter separation, and in particular to a biomedical suspended matter separation device and a separation method. Background Art

[0002] With the continuous advancement of medical technology and the deepening of biological experimental research, higher and higher requirements are placed on the precise separation and purification of suspended matter in biological samples. In the field of biomedicine, liquids such as blood, cell culture fluids, and biopharmaceutical raw materials often contain various suspended matter, such as cell fragments, protein aggregates, microorganisms, and other insoluble particles. The presence of these suspended matter will seriously affect the accuracy of experimental results and even have an adverse effect on the subsequent treatment process. Therefore, it is particularly important to develop efficient and reliable equipment and methods for separating suspended matter.

[0003] At present, there are many suspended matter separation technologies on the market, including centrifugal separation, filtration separation, membrane separation, etc. However, these methods have the following shortcomings to varying degrees: although centrifugal separation can effectively separate suspended matter, the equipment is complex, the operation is cumbersome, and the separation effect on tiny suspended matter is poor; the filtration accuracy of filtration separation is limited, it is easy to clog, and it is difficult to process multiple groups of samples at the same time, and the efficiency is low; although traditional membrane separation has the advantages of high efficiency and energy saving, the single-layer membrane structure is often difficult to meet the separation requirements of suspended matter of different sizes, and the membrane is inconvenient to replace and maintain, and it cannot meet the separation of multiple groups of suspended liquids at one time. Summary of the invention

[0004] 1. Technical issues to be resolved

[0005] In view of the deficiencies in the prior art, the present invention provides a biomedical suspended matter separation device and separation method. The device adopts an innovative design of setting up a multi-layer membrane for step-by-step separation, aiming to solve the problems existing in the prior art and improve separation efficiency and ease of operation.

[0006] (II) Technical solution

[0007] To achieve the above objectives, the present invention is implemented through the following technical solutions: A biomedical suspended solid separation device, comprising a box, a partition is vertically arranged on one side of the box, a fixed frame is arranged in the box, fixed shafts are fixedly connected on both sides of the fixed frame, one end of one of the fixed shafts is rotatably connected to the inner wall of the box, and one end of the other fixed shaft is rotatably connected to the partition, a moving frame is slidably connected to the surface of the fixed frame, a first actuator is arranged in the fixed frame to push the moving frame to slide, a bottom filter cartridge is fixedly connected to the bottom of the inner wall of the moving frame, a plurality of the bottom filter cartridges are arranged and are evenly distributed along the length direction of the moving frame, a guide rod is vertically fixedly connected to one side of the inside of the moving frame, and the number of the guide rods is the same as the number of the bottom filter cartridges, a middle filter cartridge is arranged above the bottom filter cartridge, two of the middle filter cartridges are arranged, a top filter cartridge is arranged above the middle filter cartridge, a sliding sleeve is fixedly connected to one side of the middle filter cartridge and the top filter cartridge, the sliding sleeve is slidably connected to the corresponding guide rod, a first support spring is arranged between the bottom filter cartridge and the middle filter cartridge, and adjacent two middle filter cartridges are provided with a first support spring. A second supporting spring is arranged between the filter cartridges, a third supporting spring is arranged between the middle filter cartridge and the top filter cartridge, one side of the bottom filter cartridge, the middle filter cartridge and the top filter cartridge are all connected with a first one-way sealing valve, the top of the top filter cartridge is all connected with a second one-way sealing valve and a pressure relief valve, a limiting device for limiting the sliding of the sliding sleeve is arranged on one side of the movable frame, a second actuator is vertically fixedly connected to the surface of the partition plate and one side of the interior of the box body, a pressure rod is fixedly connected to the movable end of the second actuator, and a pressure column is fixedly connected to the bottom end of the pressure rod and located above the top filter cartridge. A first valve socket is provided at the bottom of the pressure column and at a position directly corresponding to the second one-way sealing valve. A suction pump having the same number as the bottom filter cartridge is fixedly connected to one side of the top of the inner wall of the box body. A second valve socket is fixedly connected to the bottom of the inner wall of the box body. The number of the second valve sockets is equal to the number of the first one-way sealing valve. The second valve socket is provided at a position directly corresponding to the first one-way sealing valve when the fixing frame is rotated to the position where the first one-way sealing valve is vertically facing downward. A filtrate tube is connected to the bottom of the second valve socket, and one end of the filtrate tube extends to the outside of the box body.

[0008] The first valve socket includes a first cylinder, a push rod is fixedly connected to the interior of the first cylinder, one end of the push rod is fixedly connected to a push block, the second one-way sealing valve includes a second cylinder, a circular plate is fixedly connected to the interior of the second cylinder, a sliding rod is slidably connected to the center of the circular plate, one end of the sliding rod is fixedly connected to a sealing plate, the other end of the sliding rod is fixedly connected to a pressure plate, a guide cylinder is provided on the side of the circular plate close to the pressure plate, the pressure plate is slidably connected to the guide cylinder, an extrusion spring is provided between one side of the circular plate and the pressure plate, and a through hole is also opened on the surface of the circular plate.

[0009] Preferably, a connecting pipe is connected between the outlet end of the suction pump and the first valve socket, a suction pipe is connected to the inlet end of the suction pump, one end of the suction pipe extends to the box body and is connected to a suction nozzle, a fixing frame is fixedly connected between the multiple suction nozzles, and a handle is fixedly connected to one side of the fixing frame.

[0010] Preferably, one side of the bottom filter cartridge is connected to a vacuum connecting pipe, one side of the fixed frame is provided with a vacuum main pipe connected to each of the vacuum connecting pipes, one side of the interior of the box body is fixedly connected to a vacuum pump, and the connecting end of the vacuum pump is connected to one end of the vacuum main pipe.

[0011] Preferably, a servo motor is fixedly connected to one side of the interior of the box, and the output shaft end of the servo motor is fixedly connected to one end of the fixed shaft. A controller is also provided inside the box, and a display screen and control buttons electrically connected to the controller are provided on the surface of the box. The first actuator and the second actuator adopt an electric telescopic rod, and the connecting ends of the first actuator, the second actuator, the servo motor, the suction pump and the vacuum pump are electrically connected to the controller.

[0012] Preferably, a slide rail is fixedly connected to one side of the bottom of the inner wall of the box, a membrane installation frame is slidably connected to the top of the slide rail, and fixing clips for fixing the membrane are fixedly connected to both sides of the inner wall of the membrane installation frame.

[0013] Preferably, notches are provided on both sides of the fixed frame and the movable frame, and the notches are distributed at corresponding positions on the tops of the bottom filter cartridge and the middle filter cartridge when no pressure is applied. A slider is provided on one side of the bottom filter cartridge, the middle filter cartridge and the top filter cartridge, and the slider is slidably connected to the inner wall of the movable frame, and the width of the slider is greater than the width of the notch.

[0014] Preferably, the tops of the bottom filter cartridge and the middle filter cartridge are provided with cutting edges for cutting the membrane, the bottoms of the middle filter cartridge and the top filter cartridge are provided with bases adapted to the cutting edges, a cleaning box is also provided on one side of the interior of the box body, one end of the cleaning box is connected to a liquid inlet pipe, and a box cover is provided on one side of the box body.

[0015] Preferably, the limiting device includes a fixed pulley, an electric telescopic rod, a pulling rod, a fixed cylinder and a pin, the fixed cylinder is fixed to one side of the moving frame, the pin is slidably connected to the fixed cylinder and one end extends to the top of the sliding sleeve, the surface of the pin is fixedly connected to the limiting ring, a return spring is arranged between one side of the limiting ring and the fixed cylinder, the fixed pulley and the electric telescopic rod are vertically fixed to one side of the moving frame, the pulling rod is fixed to the movable end of the electric telescopic rod, a steel cable is arranged at one end of the pin, one end of the steel cable passes around the fixed pulley and is fixedly connected to the surface of the pulling rod.

[0016] A separation method for a biomedical suspended matter separation device, applicable to the above-mentioned biomedical suspended matter separation device, comprises the following steps:

[0017] Step 1: Install membranes with different pore sizes on the fixing clamp, push the membrane installation frame to one side of the fixing frame, start the second actuator, and drive the top filter cartridge and the middle filter cartridge to move downward by the downward movement of the pressure column. The limit device limits the top filter cartridge to achieve membrane cutting, and then reset the membrane installation frame;

[0018] Step 2: insert the suction nozzle into the container containing the suspension, start the suction pump, the suspension enters the top filter cartridge and is separated through the membrane, and the second actuator drives the pressure column to reset;

[0019] Step 3: Start the servo motor to drive the fixed frame to rotate around the fixed axis, so that the first one-way sealing valve is vertically downward, and then start the first actuator to move the movable frame downward. The first one-way sealing valve is connected to the second valve socket, and the separated liquid flows out from the corresponding filtrate tube.

[0020] Preferably, in step one, the pore size of the upper membrane is larger than the pore size of the lower membrane, and in step two, the vacuum pump is started.

[0021] (III) Beneficial effects

[0022] The present invention provides a biomedical suspended matter separation device and separation method, which has the following beneficial effects:

[0023] (1) This type of biomedical suspended solid separation equipment realizes multi-stage separation by providing a bottom filter cartridge, a middle filter cartridge and a top filter cartridge, and by adding membranes of different pore sizes between adjacent filter cartridges. The overall rotation facilitates the collection of filtrate. At the same time, by providing cutting edges for cutting the membrane on the bottom filter cartridge and the middle filter cartridge, the installation of the membrane is facilitated and the operation efficiency is improved. By providing multiple groups of filter cartridges, multiple groups of suspended liquids can be separated at one time, thereby improving the separation efficiency.

[0024] (2) The separation method of the biomedical suspended solid separation device facilitates the installation of the membrane by means of a membrane installation frame, and adopts a suction pump to transfer the suspension and automatically collect the filtrate, thereby reducing manual intervention. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 The overall structure of the present invention is shown in FIG. Figure 1 ;

[0026] Figure 2 The overall structure of the present invention is shown in FIG. Figure 2 ;

[0027] Figure 3 This is a schematic diagram of the first-view structure of the interior of the box of the present invention;

[0028] Figure 4 This is a schematic diagram of the structure of the interior of the box of the present invention from a second viewing angle;

[0029] Figure 5 This is a schematic diagram of the internal three-dimensional structure of the fixing frame of the present invention;

[0030] Figure 6 This is a schematic diagram of the connection between the fixed frame and the movable frame of the present invention;

[0031] Figure 7 This is a schematic diagram of the connection between the filter cartridge and the movable frame of the present invention;

[0032] Figure 8 For the present invention Figure 7 Enlarged view of point A in the middle;

[0033] Fig. 9 For the present invention Figure 5 Enlarged view of point B in the middle;

[0034] Fig.10 It is a schematic structural diagram of the first valve socket and the second one-way sealing valve of the present invention.

[0035] In the figure: 1-box, 2-fixed frame, 3-fixed shaft, 4-movable frame, 5-guide rod, 6-bottom filter cartridge, 7-middle filter cartridge, 8-top filter cartridge, 9-sliding sleeve, 10-first support spring, 11-second support spring, 12-third support spring, 13-first one-way sealing valve, 14-second one-way sealing valve, 141-second cylinder, 142-circular plate, 143-sliding rod, 144-guide cylinder, 145-pressing plate, 146-sealing plate, 147-through hole, 148-extrusion spring, 15-pressure relief valve, 16-vacuum connecting pipe, 17-partition, 18-second actuator, 19-pressing rod, 20-pressing column, 21-first valve socket, 211-first cylinder, 212-top Rod, 213-top block, 22-suction pump, 23-connecting pipe, 24-suction tube, 25-fixed frame, 26-suction nozzle, 27-handle, 28-second valve socket, 29-filtrate tube, 30-vacuum pump, 31-vacuum main pipe, 32-first actuator, 33-slider, 34-notch, 35-servo motor, 36-controller, 37-display screen, 38-control button, 39-slide rail, 40-membrane installation frame, 41-fixed clamp, 42-cleaning box, 43-liquid inlet pipe, 44-box cover, 45-fixed pulley, 46-electric telescopic rod, 47-pull rod, 48-fixed cylinder, 49-pin, 50-limiting ring, 51-reset spring, 52-steel cable, 53-cutting edge. DETAILED DESCRIPTION

[0036] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0037] See also Figure 1-10 The present invention provides a technical solution: a biomedical suspended matter separation device, comprising a box body 1, a partition 17 is vertically arranged on one side of the box body 1, a fixed frame 2 is arranged in the box body 1, and fixed shafts 3 are fixedly connected to both sides of the fixed frame 2, one end of one fixed shaft 3 is rotatably connected to the inner wall of the box body 1, and one end of the other fixed shaft 3 is rotatably connected to the partition 17, a rotating bearing is arranged between the surface of the fixed shaft 3 and the inner wall of the box body 1 and the partition 17, a moving frame 4 is slidably connected to the surface of the fixed frame 2, and the sliding direction of the moving frame 4 is the width direction of the fixed frame 2, and a first actuator 32 that drives the moving frame 4 to slide is arranged in the fixed frame 2.

[0038] A bottom filter cartridge 6 is fixedly connected to the bottom of the inner wall of the movable frame 4. There are multiple bottom filter cartridges 6 and they are evenly distributed along the length direction of the movable frame 4. In the present embodiment, there are 5 bottom filter cartridges 6. A guide rod 5 is vertically fixedly connected to one side of the interior of the movable frame 4. The number of guide rods 5 is the same as the number of bottom filter cartridges 6. A middle filter cartridge 7 is arranged above the bottom filter cartridge 6. There are two middle filter cartridges 7, or one or three, etc. A top filter cartridge 8 is arranged above the middle filter cartridge 7. A sliding sleeve 9 is fixedly connected to one side of the middle filter cartridge 7 and the top filter cartridge 8. The sliding sleeve 9 is slidably connected to the corresponding guide rod 5. A limiting device for limiting the sliding of the sliding sleeve 9 is arranged on one side of the movable frame 4. A first supporting spring 10 is arranged between the bottom filter cartridge 6 and the middle filter cartridge 7. A second supporting spring 11 is arranged between two adjacent middle filter cartridges 7. A third supporting spring 12 is arranged between the middle filter cartridge 7 and the top filter cartridge 8.

[0039] The limiting device includes a fixed pulley 45, an electric telescopic rod 46, a pull rod 47, a fixed cylinder 48 and a bayonet 49. The fixed cylinder 48 is fixed to one side of the moving frame 4. The bayonet 49 is slidably connected to the fixed cylinder 48 and one end extends to the top of the sliding sleeve 9. The sliding sleeve 9 is a sliding sleeve at the top of one side of the top filter cartridge 8. The surface of the bayonet 49 is fixedly connected to a limiting ring 50. A return spring 51 is provided between one side of the limiting ring 50 and the fixed cylinder 48. The fixed pulley 45 and the electric telescopic rod 46 are fixed to one side of the moving frame 4. The extension direction of the electric telescopic rod 46 is downward. The pull rod 47 is A steel cable 52 is provided at one end of the bayonet 49, which is fixed to the movable end of the electric telescopic rod 46. One end of the steel cable 52 passes around the fixed pulley 45 and is fixedly connected to the surface of the pull rod 47. The pull rod 47 is driven downward by the extension of the electric telescopic rod 46, and the bayonet 49 is driven to slide by the steel cable 52, so that the bayonet 49 is separated from the sliding sleeve 9. When limiting, the top filter cartridge 8 moves downward, and the sliding sleeve 9 of the top filter cartridge 8 squeezes one side of the bayonet 49, so that the reset spring 51 is compressed. When the sliding sleeve 9 moves to the bottom of the bayonet 49, the bayonet 49 is reset under the action of the reset spring 51.

[0040] With the support of the first support spring 10, the second support spring 11 and the third support spring 12, when the top filter cartridge 8 is not subjected to external force, a certain distance is maintained between the middle filter cartridge 7 and the bottom filter cartridge 6, between two adjacent middle filter cartridges 7, and between the middle filter cartridge 7 and the top filter cartridge 8, thereby facilitating the installation of the membrane.

[0041] One side of the bottom filter cartridge 6, the middle filter cartridge 7 and the top filter cartridge 8 are all connected to the first one-way sealing valve 13, and the top of the top filter cartridge 8 is connected to the second one-way sealing valve 14 and the pressure relief valve 15. The pressure relief valve 15 prevents the internal pressure from increasing when the suspension is sucked in; the second actuator 18 is vertically fixedly connected to the surface of the partition 17 and one side of the interior of the box body 1, and the movable end of the second actuator 18 is fixedly connected to a pressure rod 19, and the bottom end of the pressure rod 19 is fixedly connected to a pressure column 20 located above the top filter cartridge 8, and the bottom of the pressure column 20 is located at the position corresponding to the second one-way sealing valve 14. A first valve socket 21 is provided. When the second actuator 18 contracts, the pressure rod 19 moves downward, driving the pressure column 20 to apply pressure to the top of the top filter cartridge 8, and the top filter cartridge 8 moves downward until the filter cartridges are fitted together. At this time, the space formed inside each filter cartridge is a sealed space.

[0042] A suction pump 22 having the same number as the bottom filter cartridge 6 is fixedly connected to one side of the top of the inner wall of the box body 1, and a second valve socket 28 is fixedly connected to the bottom of the inner wall of the box body 1, wherein the first one-way sealing valve 13 and the second one-way sealing valve 14 have the same structure, and the first valve socket 21 and the second valve socket 28 have the same structure.

[0043] The first valve socket 21 includes a first cylinder 211, a push rod 212 is fixedly connected inside the first cylinder 211, and a push block 213 is fixedly connected at one end of the push rod 212. The second one-way sealing valve 14 includes a second cylinder 141, a circular plate 142 is fixedly connected inside the second cylinder 141, a sliding rod 143 is slidably connected at the center of the circular plate 142, a sealing plate 146 is fixedly connected at one end of the sliding rod 143, a pressing plate 145 is fixedly connected at the other end of the sliding rod 143, and a guide cylinder 144 is provided on one side of the circular plate 142 close to the pressing plate 145. The pressure plate 145 is slidably connected with the guide cylinder 144, an extrusion spring 148 is arranged between one side of the circular plate 142 and the pressure plate 145, and a through hole 147 is also opened on the surface of the circular plate 142. When the pressure column 20 moves downward, the first valve socket 21 applies pressure to the pressure plate 145 through the top block 213, the extrusion spring 148 contracts, the sealing plate 146 is separated from the circular plate 142, and the through hole 147 is exposed, thereby realizing the connection between the first valve socket 21 and the second one-way sealing valve 14, and the connection process between the first one-way sealing valve 13 and the second valve socket 28 is the same.

[0044] The number of second valve sockets 28 is equal to the number of first one-way sealing valves 13. The second valve sockets 28 are arranged at the position directly corresponding to the first one-way sealing valve 13 when the fixed frame 2 is rotated to the position where the first one-way sealing valve 13 is vertically downward. The bottom of the second valve socket 28 is connected to a filtrate tube 29, and one end of the filtrate tube 29 extends to the outside of the box body 1. Through the arrangement of multiple filter cartridges and the installation of membranes with different pore sizes, multi-stage separation of the suspension can be achieved. Subsequently, by rotating the fixed frame 2 and moving the movable frame 4 downward, the first one-way sealing valve 13 is connected to the second valve socket 28, ensuring that the separated filtrate can flow out of the corresponding filtrate tube 29, thereby realizing the collection of the filtrate and improving the overall work efficiency.

[0045] A connecting pipe 23 is connected between the outlet end of the suction pump 22 and the first valve socket 21, and a suction pipe 24 is connected to the inlet end of the suction pump 22. One end of the suction pipe 24 extends to the box body 1 and is connected to a suction nozzle 26. A fixing frame 25 is fixedly connected between the multiple suction nozzles 26, and a handle 27 is fixedly connected to one side of the fixing frame 25. Multiple suction nozzles 26 can be operated at one time through the handle 27 and the fixing frame 25, thereby realizing the separation operation of multiple groups of suspensions at one time.

[0046] One side of the bottom filter cartridge 6 is connected to a vacuum connecting pipe 16, one side of the fixed frame 2 is provided with a vacuum main pipe 31 connected to each vacuum connecting pipe 16, one side of the interior of the box body 1 is fixedly connected to a vacuum pump 30, and the connecting end of the vacuum pump 30 is connected to one end of the vacuum main pipe 31. The action of the vacuum pump 30 creates a negative pressure environment in the filter cartridge, thereby increasing the separation speed.

[0047] A servo motor 35 is fixedly connected to one side of the interior of the box body 1, and the output shaft end of the servo motor 35 is fixedly connected to one end of the fixed shaft 3. A controller 36 is also provided inside the box body 1. A display screen 37 and a control button 38 electrically connected to the controller 36 are provided on the surface of the box body 1. The first actuator 32 and the second actuator 18 adopt an electric telescopic rod. The connecting ends of the first actuator 32, the second actuator 18, the servo motor 35, the suction pump 22 and the vacuum pump 30 are electrically connected to the controller 36. The servo motor 35 can drive the fixed frame 2 to rotate. When the fixed frame 2 is in the separated state, the top is parallel to the top of the box body 1. When the fixed frame 2 is in the filtrate collecting state, the top is perpendicular to the top of the box body 1. Therefore, the servo motor 35 drives the fixed frame 2 to rotate at an angle of ninety degrees.

[0048] A slide rail 39 is fixedly connected to one side of the bottom inner wall of the box body 1, and a membrane mounting frame 40 is slidably connected to the top of the slide rail 39. Fixing clips 41 for fixing the membrane are fixedly connected to both sides of the inner wall of the membrane mounting frame 40. The membrane is fixed by the fixing clips 41, and then the membrane mounting frame 40 is slid along the slide rail 39 to drive the membrane to the top of the filter cartridge. A cutting edge 53 for cutting the membrane is provided on the top of the bottom filter cartridge 6 and the middle filter cartridge 7, and a base adapted to the cutting edge 53 is provided on the bottom of the middle filter cartridge 7 and the top filter cartridge 8. The cutting edge 53 is used to cut the membrane by moving the middle filter cartridge 7 and the top filter cartridge 8 downward, thereby facilitating the installation of the membrane and improving work efficiency.

[0049] A cleaning box 42 is also provided on one side of the interior of the box body 1. One end of the cleaning box 42 is connected to a liquid inlet pipe 43. Cleaning liquid is added to the cleaning box through the liquid inlet pipe 43. The interior is easily cleaned through the suction nozzle 26 and the suction pump 22. One side of the cleaning box 42 also extends to the outside of the box body 1, and a placement hole is provided on the part extending to the outside to facilitate the placement of the suction nozzle 26. A box cover 44 is provided on one side of the box body 1.

[0050] Notches 34 are provided on both sides of the fixed frame 2 and the movable frame 4. The notches 34 are distributed at corresponding positions on the tops of the bottom filter cartridge 6 and the middle filter cartridge 7 when no pressure is applied. The notches 34 are provided to facilitate the membrane to move to the top of the filter cartridge when the membrane mounting frame 40 moves. Slide blocks 33 are provided on one side of the bottom filter cartridge 6, the middle filter cartridge 7 and the top filter cartridge 8. The slide blocks 33 are slidably connected to the inner wall of the movable frame 4. The width of the slide blocks 33 is greater than the width of the notches 34, thereby ensuring the stable sliding of the middle filter cartridge 7 and the top filter cartridge 8. A connecting rod is provided between the adjacent middle filter cartridges 7 and the adjacent top filter cartridges 8 on the same layer to ensure the overall stability.

[0051] A separation method for a biomedical suspended matter separation device, applicable to the above-mentioned biomedical suspended matter separation device, comprises the following steps:

[0052] Step 1: Install membranes with different pore sizes on the fixing clamp 41, push the membrane installation frame 40 to one side of the fixing frame 2, start the second actuator 18, and drive the top filter cartridge 8 and the middle filter cartridge 7 to move downward by the pressure column 20, and the limiting device limits the top filter cartridge 8 to achieve membrane cutting, and then reset the membrane installation frame 40;

[0053] Step 2: insert the suction nozzle 26 into the container containing the suspension, start the suction pump 22, the suspension enters the top filter cartridge 8 and is separated by the membrane, and the second actuator 18 drives the pressure column 20 to reset;

[0054] Step 3: Start the servo motor 35 to drive the fixed frame 2 to rotate around the fixed axis 3, so that the first one-way sealing valve 13 is vertically downward, and then start the first actuator 32 to move the movable frame 4 downward. The first one-way sealing valve is connected to the second valve socket 28, and the separated liquid flows out from the corresponding filtrate tube 29.

[0055] In step one, the pore size of the upper membrane is larger than the pore size of the lower membrane, and in step two, the vacuum pump 30 is started.

[0056] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, the elements defined by the statement "comprise a ..." do not exclude the existence of other identical elements in the process, method, article or device including the elements.

[0057] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A biomedical suspended matter separation device, comprising a housing (1), wherein a partition (17) is vertically arranged on one side of the housing (1), and characterized in that: A fixed frame (2) is provided in the box body (1), and fixed shafts (3) are fixedly connected to both sides of the fixed frame (2), one end of one of the fixed shafts (3) is rotatably connected to the inner wall of the box body (1), and one end of the other fixed shaft (3) is rotatably connected to the partition (17). A movable frame (4) is slidably connected to the surface of the fixed frame (2), and a first actuator (32) for pushing the movable frame (4) to slide is provided in the fixed frame (2). A bottom filter cartridge (6) is fixedly connected to the bottom of the inner wall of the movable frame (4), and a plurality of bottom filter cartridges (6) are provided and are evenly distributed along the length direction of the movable frame (4). One side of the interior of the movable frame (4) is vertically fixedly connected to Guide rods (5), the number of the guide rods (5) being the same as the number of the bottom filter cartridges (6), a middle filter cartridge (7) being arranged above the bottom filter cartridge (6), two middle filter cartridges (7) being arranged, a top filter cartridge (8) being arranged above the middle filter cartridge (7), a sliding sleeve (9) being fixedly connected to one side of the middle filter cartridge (7) and the top filter cartridge (8), the sliding sleeve (9) being slidably connected to the corresponding guide rod (5), a first supporting spring (10) being arranged between the bottom filter cartridge (6) and the middle filter cartridge (7), a second supporting spring (11) being arranged between two adjacent middle filter cartridges (7), and a third supporting spring (12) being arranged between the middle filter cartridge (7) and the top filter cartridge (8). 2), one side of the bottom filter cartridge (6), the middle filter cartridge (7) and the top filter cartridge (8) are all connected to a first one-way sealing valve (13), the top of the top filter cartridge (8) is connected to a second one-way sealing valve (14) and a pressure relief valve (15), one side of the movable frame (4) is provided with a limit device for limiting the sliding of the sliding sleeve (9), the surface of the partition plate (17) and one side of the interior of the box body (1) are vertically fixedly connected to a second actuator (18), the movable end of the second actuator (18) is fixedly connected to a pressure rod (19), the bottom end of the pressure rod (19) and located above the top filter cartridge (8) is fixedly connected to a pressure column (20), the bottom of the pressure column (20) and located above the second one-way sealing valve (14) is fixedly connected to the pressure column (20), and the bottom of the pressure column (20) and located above the second one-way sealing valve (14) is fixedly connected to the pressure column (20). A first valve socket (21) is arranged at a position directly corresponding to the sealing valve (14); a suction pump (22) having the same number as the bottom filter cartridge (6) is fixedly connected to one side of the top of the inner wall of the box body (1); a second valve socket (28) is fixedly connected to the bottom of the inner wall of the box body (1); the number of the second valve sockets (28) is equal to the number of the first one-way sealing valves (13); the second valve socket (28) is arranged at a position directly corresponding to the first one-way sealing valve (13) when the fixing frame (2) is rotated to the position where the first one-way sealing valve (13) is vertically downward; the bottom of the second valve socket (28) is connected to a filtrate pipe (29); one end of the filtrate pipe (29) extends to the outside of the box body (1); The first valve socket (21) comprises a first cylinder (211), a push rod (212) is fixedly connected inside the first cylinder (211), and one end of the push rod (212) is fixedly connected to a push block (213); the second one-way sealing valve (14) comprises a second cylinder (141), a circular plate (142) is fixedly connected inside the second cylinder (141), a sliding rod (143) is slidably connected to the center of the circular plate (142), one end of the sliding rod (143) is fixedly connected to a sealing plate (146), and the other end of the sliding rod (143) is fixedly connected to a pressure plate (145); a guide cylinder (144) is provided on a side of the circular plate (142) close to the pressure plate (145), and the pressure plate (145) is slidably connected to the guide cylinder (144); a pressing spring (148) is provided between one side of the circular plate (142) and the pressure plate (145), and a through hole (147) is also provided on the surface of the circular plate (142).

2. A biomedical suspension separation device according to claim 1, characterized in that: A connecting pipe (23) is connected between the outlet end of the suction pump (22) and the first valve socket (21), and a suction pipe (24) is connected to the inlet end of the suction pump (22). One end of the suction pipe (24) extends to the box body (1) and is connected to a suction nozzle (26). A fixing frame (25) is fixedly connected between the plurality of suction nozzles (26), and a handle (27) is fixedly connected to one side of the fixing frame (25).

3. A biomedical suspension separation device according to claim 2, characterized in that: One side of the bottom filter cartridge (6) is connected to a vacuum connecting pipe (16), one side of the fixed frame (2) is provided with a vacuum main pipe (31) connected to each of the vacuum connecting pipes (16), and one side of the interior of the box body (1) is fixedly connected to a vacuum pump (30), and a connection end of the vacuum pump (30) is connected to one end of the vacuum main pipe (31).

4. A biomedical suspension separation device according to claim 3, characterized in that: A servo motor (35) is fixedly connected to one side of the interior of the box (1), and an output shaft end of the servo motor (35) is fixedly connected to one end of the fixed shaft (3). A controller (36) is also provided inside the box (1), and a display screen (37) and control buttons (38) electrically connected to the controller (36) are provided on the surface of the box (1). The first actuator (32) and the second actuator (18) use electric telescopic rods, and the connection ends of the first actuator (32), the second actuator (18), the servo motor (35), the suction pump (22) and the vacuum pump (30) are electrically connected to the controller (36).

5. A biomedical suspension separation device according to claim 4, characterized in that: A slide rail (39) is fixedly connected to one side of the bottom of the inner wall of the box body (1), a membrane installation frame (40) is slidably connected to the top of the slide rail (39), and fixing clamps (41) for fixing the membrane are fixedly connected to both sides of the inner wall of the membrane installation frame (40).

6. A biomedical suspension separation device according to claim 5, characterized in that: Notches (34) are provided on both sides of the fixed frame (2) and the movable frame (4), and the notches (34) are distributed at corresponding positions on the tops of the bottom filter cartridge (6) and the middle filter cartridge (7) when no pressure is applied. A slider (33) is provided on one side of the bottom filter cartridge (6), the middle filter cartridge (7) and the top filter cartridge (8), and the slider (33) is slidably connected to the inner wall of the movable frame (4), and the width of the slider (33) is greater than the width of the notch (34).

7. A biomedical suspension separation device according to claim 6, characterized in that: The tops of the bottom filter cartridge (6) and the middle filter cartridge (7) are provided with cutting edges (53) for cutting the membrane, and the bottoms of the middle filter cartridge (7) and the top filter cartridge (8) are provided with bases adapted to the cutting edges (53). A cleaning box (42) is also provided on one side of the interior of the box body (1), and one end of the cleaning box (42) is connected to a liquid inlet pipe (43). A box cover (44) is provided on one side of the box body (1).

8. The biomedical suspension separation device according to claim 1, characterized in that: The limiting device comprises a fixed pulley (45), an electric telescopic rod (46), a pull rod (47), a fixed cylinder (48) and a bayonet (49); the fixed cylinder (48) is fixed to one side of the moving frame (4); the bayonet (49) is slidably connected to the fixed cylinder (48) and one end of the bayonet (49) extends above the sliding sleeve (9); a limiting ring (50) is fixedly connected to the surface of the bayonet (49); a return spring (51) is provided between one side of the limiting ring (50) and the fixed cylinder (48); the fixed pulley (45) and the electric telescopic rod (46) are vertically fixed to one side of the moving frame (4); the pull rod (47) is fixed to the movable end of the electric telescopic rod (46); a steel cable (52) is provided at one end of the bayonet (49); one end of the steel cable (52) passes around the fixed pulley (45) and is fixedly connected to the surface of the pull rod (47).

9. A separation method of a biomedical suspended matter separation device, applicable to a biomedical suspended matter separation device according to any one of claims 5 to 7, characterized in that: The following steps are involved: Step 1: Install membranes of different pore sizes on the fixing clamp (41), push the membrane installation frame (40) to one side of the fixing frame (2), start the second actuator (18), and drive the top filter cartridge (8) and the middle filter cartridge (7) to move downward by the pressure column (20), and the limiting device limits the top filter cartridge (8) to achieve membrane cutting, and then reset the membrane installation frame (40); Step 2: inserting the suction nozzle (26) into the container containing the suspension, starting the suction pump (22), the suspension enters the top filter cartridge (8) and is separated by the membrane, and the second actuator (18) drives the pressure column (20) to reset; Step 3: Start the servo motor (35) to drive the fixed frame (2) to rotate around the fixed axis (3), so that the first one-way sealing valve (13) is vertically downward, and then start the first actuator (32) to move the movable frame (4) downward, so that the first one-way sealing valve is connected to the second valve socket (28), and the separated liquid flows out from the corresponding filtrate tube (29).

10. The separation method of a biomedical suspension separation device according to claim 9, characterized in that: In step one, the pore size of the upper membrane is larger than the pore size of the lower membrane, and in step two, the vacuum pump (30) is started.

Images