Conveying device

Abstract

The embodiment of the invention relates to the technical field of medical instruments, and discloses a conveying device. When an operator continuously operates the conveying device to enable the movable part to continuously move, the acting force of the buffering part on the wire fixing part is increased slowly, and the tension of the driving wire is correspondingly increased slowly, so that the other parts of human tissues and organs or prostheses acted by the movable part can be prevented from being damaged; and on the other hand, the elastic property of the buffer part is generally much smaller than the tensile modulus of the driving wire, so that the deformation quantity of the driving wire, which is generated by the acting force of the wire fixing part (namely transmission of the acting force of the buffer part to the wire fixing part), on the driving wire is much smaller than the axial displacement quantity of the second moving part, and the driving wire can be prevented from being broken.

Description

Technical Field

[0001] The embodiments of the present invention relate to the technical field of medical devices, and in particular to a conveying device. Background Art

[0002] The mitral valve is located between the left atrium and the left ventricle. When the heart is in diastole, the mitral valve opens to allow blood from the left atrium to flow to the left ventricle. When the heart is in contraction, the mitral valve closes to allow the pumped blood to flow into the aorta instead of flowing back to the left atrium. That is, the mitral valve can act as a one-way valve. If the mitral valve fails to close completely during heart contraction, part of the blood in the left ventricle will flow back to the left atrium, which is called "mitral regurgitation" (MR). When mitral regurgitation occurs, it means that the mitral valve can no longer play the role of a one-way valve. When the heart contracts, part of the blood flows back to the left atrium, the forward blood flow is reduced, and the heart's pumping function is limited. When the degree of mitral regurgitation is severe, it can cause a variety of complications such as atrial fibrillation, pulmonary hypertension, congestive heart failure, blood clots and stroke. Therefore, patients with severe mitral regurgitation are in urgent need of effective treatment.

[0003] Traditionally, MR is treated through open-chest surgery, one of which involves suturing the edges of the mitral valve leaflets directly to each other (called the "Alfieri" suture), which is extremely difficult and prone to many complications.

[0004] With the development of interventional technology, various interventional procedures have emerged, such as the transcatheter edge-to-edge repair (TEER) of the mitral valve that simulates the above-mentioned "Alfieri" suture. In the TEER procedure, the transcatheter mitral valve repair system includes a mitral valve clip and a delivery device. The mitral valve clip is introduced through the femoral vein under the guidance of three-dimensional ultrasound and DSA, passed through the atrial septum, and delivered to the left atrium and left ventricle through the delivery device. The mitral valve clip then clamps the edges of the mitral valve leaflets (i.e., the anterior leaflet and the posterior leaflet), so that the mitral valve changes from a large unclosed single hole to a small double hole during systole, thereby reducing mitral valve regurgitation. Compared with surgical edge-to-edge repair, TEER has the advantages of less trauma, shorter operation time, and higher safety, and is expected to improve the cure rate of MR.

[0005] However, the existing transcatheter mitral valve repair system still has many shortcomings. For example, after the mitral valve clip clamps the valve leaflet, if the operator continues to operate the delivery device, the clamping force of the mitral valve clip on the valve leaflet will increase rapidly, which may damage the valve leaflet. On the other hand, continuing to operate the delivery device may also cause the drive wire to break. Summary of the invention

[0006] The purpose of the embodiment of the present invention is to provide a delivery device to solve the problem that after the mitral valve clip clamps the valve leaflet, if the operation continues, the valve leaflet may be damaged or the drive wire may be broken.

[0007] In order to solve the above technical problems, the first aspect of the present invention provides a delivery device for delivering a prosthesis having a movable part, comprising:

[0008] a housing; a driving assembly, comprising a moving part, the moving part being movably accommodated in the housing relative to the housing along the axial direction of the housing; a wire fixing part, the wire fixing part being movably accommodated in the moving part; a driving wire, the proximal end of the driving wire being fixed to the wire fixing part, and the distal end of the driving wire being used for detachably connecting the prosthesis; the moving part drives the driving wire to move axially via the wire fixing part to drive the movable part to move; a buffer part, the buffer part is located between the moving part and the wire fixing part, and is used to apply pre-tightening forces in opposite directions to the moving part and the wire fixing part respectively, so that the moving part and the wire fixing part have a movement tendency to move away from each other; a limiting assembly, the limiting assembly is configured to prevent the wire fixing part from moving toward the proximal end under the action of the pre-tightening force.

[0009] Optionally, the movable member includes an axially extending movable channel, the movable channel includes a first sub-channel and a second sub-channel, the first sub-channel is located on the distal side of the second sub-channel, and the inner diameter of the first sub-channel is smaller than the inner diameter of the second sub-channel, so as to form a first abutment surface at the connection between the first sub-channel and the second sub-channel; the wire fixing member includes a first section and a second section, the outer diameter of the first section is smaller than the outer diameter of the second section, so as to form a second abutment surface at the connection between the first section and the second section, the first section is partially accommodated in the first sub-channel, the second section is partially accommodated in the second sub-channel, and the buffer member is located between the first abutment surface and the second abutment surface.

[0010] Optionally, the movable member includes an axially extending movable channel, the end face of the proximal end of the movable member is defined as a first abutment surface, the wire fixing member includes a first section and a second section, the outer diameter of the first section is smaller than the outer diameter of the second section, so as to form a second abutment surface at the connection between the first section and the second section, the first section is partially accommodated in the movable channel, and the second section is located on the proximal side of the movable member and outside the movable channel; the buffer member is located between the first abutment surface and the second abutment surface.

[0011] Optionally, the limiting assembly includes a slide groove which is arranged at the proximal end of the movable member and extends axially, and a sliding portion which is arranged at the proximal end of the wire fixing member, and the sliding portion is movably arranged in the slide groove to couple the movable member and the wire fixing member.

[0012] Optionally, there are a plurality of slide grooves, which are spaced apart along the circumference of the movable member; there are a plurality of sliding parts, which are spaced apart along the circumference of the wire fixing member; and at least one sliding part is accommodated in at least a portion of the slide grooves.

[0013] Optionally, the limiting assembly includes a snap-fit ​​cover and a limiting member arranged at the proximal end of the movable member, the snap-fit ​​cover abuts the proximal end of the wire fixing member and couples the limiting member so that the movable member and the wire fixing member remain axially relatively still under the action of the preload force.

[0014] Optionally, the snap-on cover comprises an abutting portion and a limiting portion which are fixedly connected, the abutting portion is arranged at a proximal end of the limiting portion for abutting against a proximal end of the wire fixing member, and the limiting portion is used for coupling with the limiting member.

[0015] Optionally, the snap-on cover also includes a connecting portion fixedly connecting the abutting portion and the limiting portion, the connecting portion is circumferentially arranged along the abutting portion and extends axially; the limiting portion is located at one end of the connecting portion away from the abutting portion, and the limiting portion is used to engage with the limiting member.

[0016] Optionally, the limiting portion is a first protrusion extending radially toward the moving part, and the limiting part is a second protrusion arranged along the circumference of the moving part and extending radially toward the snap-fit ​​cover, the first protrusion includes a first sliding surface and a third abutting surface, and the first sliding surface is located on the distal side of the third abutting surface; the second protrusion includes a second sliding surface and a fourth abutting surface, and the second sliding surface is located on the proximal side of the fourth abutting surface; the first sliding surface is configured to slide relative to the second sliding surface when the snap-fit ​​cover is engaged with the limiting part; the third abutting surface is configured to abut against the fourth abutting surface after the snap-fit ​​cover is engaged with the limiting part.

[0017] Optionally, the buffer member is an elastic member, a hydraulic buffer or a pneumatic buffer.

[0018] Optionally, the elastic member is a compression spring or a rubber ring sleeved on the wire fixing member.

[0019] A second aspect of the present invention provides another delivery device, comprising:

[0020] A housing; a driving assembly, comprising a moving member, the moving member is movably accommodated in the housing relative to the housing along the axial direction of the housing; a wire fixing member, the wire fixing member is movably accommodated in the moving member; a driving wire, the proximal end of the driving wire is fixed to the wire fixing member, and the distal end of the driving wire is used to detachably connect the prosthesis; the moving member drives the driving wire to move axially via the wire fixing member to drive the movable member to move; a limiting assembly, comprising a first limiting portion arranged on the moving member and a second limiting portion arranged on the wire fixing member; a buffer, the buffer is located between the moving member and the second limiting portion, the buffer is used to apply a first preload to the moving member, and a second preload is applied to the wire fixing member through the second limiting portion, so that the moving member and the wire fixing member have a movement tendency away from each other, and the first preload is equal to the second preload and opposite in direction; the limiting assembly is configured to prevent the wire fixing member from moving toward the proximal end under the action of the second preload by cooperating with the first limiting portion and the second limiting portion.

[0021] Optionally, the first limiting portion is a slide groove which is arranged at the proximal end of the movable member and extends axially, and the second limiting portion is a sliding portion which is arranged at the proximal end of the wire fixing member, and the sliding portion is movably arranged in the slide groove.

[0022] Optionally, the movable member includes an axially extending movable channel, the movable channel includes a first sub-channel and a second sub-channel, the first sub-channel is located on the distal side of the second sub-channel, and the inner diameter of the first sub-channel is smaller than the inner diameter of the second sub-channel, so as to form a first abutment surface at the connection between the first sub-channel and the second sub-channel; the wire fixing member is accommodated in the movable channel, and the buffer member is located between the first abutment surface and the distal end face of the sliding portion.

[0023] Compared with the related art, in the embodiments of the present invention, when the operator continuously operates the conveying device to make the movable part move continuously, especially after the tension of the driving wire is greater than the pre-tightening force, the force exerted by the buffer member on the wire fixing part increases slowly, and correspondingly, the tension of the driving wire also increases slowly, thereby avoiding damage to the human tissue organs or other parts of the prosthesis acted upon by the movable part; on the other hand, since the elastic properties of the buffer member itself are generally much smaller than the tensile modulus of the driving wire, the deformation amount of the driving wire caused by the force exerted by the wire fixing member (that is, the transmission of the force exerted by the buffer member to the wire fixing member) is much smaller than the axial displacement of the second movable part, which can avoid the breakage of the driving wire and provide good protection for the driving wire. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] One or more embodiments are exemplarily described by pictures in the corresponding drawings, and these exemplified descriptions do not constitute limitations on the embodiments. Elements with the same reference numerals in the drawings represent similar elements, and unless otherwise stated, the figures in the drawings do not constitute proportional limitations.

[0025] Figure 1 This is a schematic diagram of delivering a mitral valve clip to the mitral valve through a catheter so that the mitral valve clip clamps the anterior leaflet and the posterior leaflet of the mitral valve;

[0026] Figure 2 It is a schematic diagram of the mitral valve leaflets being clamped by the mitral valve clip;

[0027] Figure 3 It is a schematic diagram of the structure of the mitral valve clip when the arms are closed;

[0028] Figure 4 It is a schematic diagram of the structure of the mitral valve clip when the clip arms are opened;

[0029] Figure 5 is a cross-sectional view of the proximal end portion of a prior art delivery device in the axial direction;

[0030] Figure 6 is a side view schematic diagram of a conveying device according to an embodiment of the present invention;

[0031] Figure 7 is a cross-sectional view of the proximal end portion of the delivery device according to an embodiment of the present invention in the axial direction;

[0032] Figure 8 is a cross-sectional view of a moving part of a conveying device according to an embodiment of the present invention in the axial direction;

[0033] Fig. 9 is a cross-sectional view of a wire fixing member of a conveying device according to an embodiment of the present invention in the axial direction;

[0034] Fig.10 is a cross-sectional view of a snap-fit ​​cover of a conveying device according to an embodiment of the present invention in the axial direction;

[0035] Fig.11 is a cross-sectional view of the proximal end portion of the housing of the delivery device according to an embodiment of the present invention in the axial direction;

[0036] Fig.12 is a cross-sectional view of a driving member of a conveying device according to an embodiment of the present invention in the axial direction;

[0037] Fig.13 FIG. 4 is a cross-sectional view of the proximal end portion of a delivery device according to another embodiment of the present invention in the axial direction. DETAILED DESCRIPTION

[0038] In order to make the purpose, technical scheme and advantages of the embodiments of the present invention clearer, the following will be described in detail with reference to the accompanying drawings. However, it will be appreciated by those skilled in the art that in the various embodiments of the present invention, many technical details are provided in order to enable the reader to better understand the present application. However, even without these technical details and various changes and modifications based on the following embodiments, the technical scheme claimed in the present application can be implemented.

[0039] In the embodiments of the present invention, the terms "upper", "lower", "left", "right", "front", "back", "top", "bottom", "inner", "outer", "middle", "vertical", "horizontal", "lateral", "longitudinal" and the like indicating directions or positional relationships are based on the directions or positional relationships shown in the accompanying drawings. These terms are mainly used to better describe the present invention and its embodiments, and are not used to limit the indicated devices, elements or components to have a specific direction, or to be constructed and operated in a specific direction.

[0040] In addition, some of the above terms may be used to express other meanings in addition to indicating orientation or positional relationship. For example, the term "on" may also be used to express a certain dependency or connection relationship in some cases. For those skilled in the art, the specific meanings of these terms in the present invention can be understood according to specific circumstances.

[0041] In addition, the terms "installed", "set", "provided with", "opened", "connected", and "connected" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral structure; it can be a mechanical connection, or an electrical connection; it can be a direct connection, or an indirect connection through an intermediate medium, or it can be an internal connection between two devices, elements, or components. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0042] In addition, the terms "first", "second", etc. are mainly used to distinguish different devices, elements or components (the specific types and structures may be the same or different), and are not used to indicate or imply the relative importance and quantity of the indicated devices, elements or components. Unless otherwise specified, "plurality" means two or more.

[0043] The present invention does not specifically limit the prosthesis, which may be a mitral valve clip for clamping the mitral valve leaflets to treat mitral valve regurgitation, a valve clip for clamping other valves, such as a tricuspid valve clip for clamping the tricuspid valve to treat tricuspid valve regurgitation, or other prostheses with movable parts. The present invention is explained below using the mitral valve clip as an example of the prosthesis.

[0044] See also Figures 1 to 4The mitral valve clip 100 includes a base 110, a clamp arm 120 (i.e., a movable part) and a clip 130. There are two clamp arms 120 and two clips 130, respectively. The clamp arm 120 is located on one side of the distal end of the clip 130, and the two clamp arms 120 and the two clips 130 are symmetrically arranged on both sides of the base 110, respectively. There is a clamping space between the clamp arm 120 and the clip 130 located on the same side of the base 110 for accommodating the leaflets. Both the clamp arm 120 and the clip 130 are rotatably connected to the base 110, and can rotate relative to the base 110 to change the angle with the axis of the base 110, thereby increasing or decreasing the clamping space. In this way, the mitral valve leaflets (i.e., the anterior leaflet and the posterior leaflet) can be clamped by controlling the relative movement between the clamp arm 120 and the clip 130.

[0045] Specifically, the clamp arm 120 includes a first clamp arm 121 and a second clamp arm 122, and the first clamp arm 121 and the second clamp arm 122 are symmetrically arranged with the axis of the base 110 as the axis of symmetry. Preferably, the axis of the base 110 is located in the plane where the movement paths of the first clamp arm 121 and the second clamp arm 122 are located, so as to better clamp the edge of the mitral valve leaflet 300. Here, "the plane where the movement paths of the first clamp arm 121 and the second clamp arm 122 are located" refers to the movement path when the first clamp arm 121 and the second clamp arm 122 rotate relative to the base 110. Preferably, the first clamp arm 121 and the second clamp arm 122 are pivotally connected to the base 110 at the same position, and at this time, the first clamp arm 121 and the second clamp arm 122 can use the same pivot axis. Correspondingly, the clip 130 includes a first clip 131 and a second clip 132, and the two clips are arranged one-to-one with the two clamp arms and are both located at the proximal end of the corresponding clamp arms.

[0046] The mitral clip 100 may further include an actuating assembly 140, which may include a base 141, a first clamp arm link 142, and a second clamp arm link 143. One end of the first clamp arm link 142 is pivotally connected to the first clamp arm 121, and the other end is pivotally connected to the base 141; one end of the second clamp arm link 143 is pivotally connected to the second clamp arm 122, and the other end is pivotally connected to the base 141. The base 110 includes an axially extending receiving channel, and the base 141 is generally "T"-shaped. The two ends of the horizontal arm perpendicular to the axial direction of the base 110 are pivotally connected to the first clamp arm link 142 and the second clamp arm link 143, respectively. One end of the straight arm extending in the axial direction is connected to the horizontal arm, and the other end is received in the receiving channel and is detachably connected to the driving wire 240 of the conveying device described below, and can move axially relative to the base 110. In this way, the base 110, the base 141, the first clamp arm link 142 and the first clamp arm 121 form a mechanism similar to a connecting rod slider mechanism. Similarly, the base 110, the base 141, the second clamp arm link 143 and the second clamp arm 122 form a mechanism similar to a connecting rod slider mechanism. When the base 110 remains relatively stationary, the drive wire 240 drives the base 141 to move axially relative to the base 110, thereby causing the first clamp arm 121 and the second clamp arm 122 to rotate, so as to clamp the leaflet edge with the assistance of the first clamp 131 and the second clamp 132. More specifically, when the drive wire moves toward the proximal end, the first clamp arm 121 and the second clamp arm 122 rotate and move closer to the base 110, and when the drive wire moves toward the distal end, the first clamp arm 121 and the second clamp arm 122 rotate and move away from the base 110.

[0047] See also Figure 1 as well as Figure 4 , the mitral valve clip 100 goes from the femoral vein to the inferior vena cava and then to the right atrium, and after passing through the atrial septum, enters the left atrium 400 and the left ventricle 500, and then clamps the edge of the mitral valve leaflet 300, thereby reducing mitral valve regurgitation. To achieve the above purpose, a delivery device is generally used to allow the mitral valve clip 100 to enter the left atrium 400 in a shape with the smallest possible profile (at this time, the clamp arm and the base are basically parallel to each other), and then the clamp arm 120 of the mitral valve clip 100 is driven to rotate and unfold, pass through the mitral valve at a suitable angle and enter the left ventricle 500, and after the edges of the anterior and posterior valves enter the clamping space, the clip 130 is released, and the clamp arm 120 is rotated to narrow the clamping space until the clamp arm 120 and the clip 130 cooperate to clamp the mitral valve leaflet 300.

[0048] Please refer to Figure 5In the existing conveying device, the first moving member 150 drives the rotating shaft 160 of the fixed driving wire 240 to move axially so that the clamping arm 120 moves. The first moving member 150 is provided with a first positioning through groove, and the outer wall of the rotating shaft 160 is provided with a second positioning through groove. The cross-sectional shape of the first positioning through groove and the cross-sectional shape of the second positioning through groove are configured to cooperate with each other to form a closed shape, so that the first positioning through groove and the second positioning through groove after cooperation form a positioning through hole 170. The positioning pin 180 is penetrated in the positioning through hole 170 so that the first moving member 150 and the rotating shaft 160 are relatively fixed, and only when the first moving member 150 moves, the rotating shaft 160 will follow and move. Thus, due to the effect of the positioning pin 180, the first moving member 150 and the rotating shaft 160 form an integral body.

[0049] The inventors have found that after the mitral valve clip 100 is driven and clamps the anterior and posterior mitral valves, the clamp arm 120 and the base 110 form a certain angle, that is, the first moving member 150 still has an excess stroke that allows the clamp arm 120 to move from a certain angle with the base 110 to a position substantially parallel to the base 110. If the operator continues to operate Figure 5 The prior art device shown in the figure drives the driving wire 240 to move to the proximal end by the first movable member 150, and the driving wire 240 can still drive the clamping arm 120, and the clamping arm 120 still can apply force to the anterior flap and the posterior flap. At this moment, the anterior flap and the posterior flap may be damaged. Particularly when the anterior flap and the posterior flap of the patient are thicker, if the operator continues to operate the driving wire 240 according to habit, even if the operator operates the driving wire 240 to move less distance, the above situation is also easy to occur. On the other hand, because the anterior flap and the posterior flap leaflet of the clamped mitral valve are similar to a rigid body, the clamping arm 120 can not continue to deflect, and the driving wire 240 can not continue to move to the proximal end as a whole. At this moment, the operating force that the driving wire 240 is subjected to can only cause the driving wire 240 to produce deformation, and the spare stroke of the first movable member 150 is often greater than the maximum deformation amount of the driving wire 240, which causes when continuing to operate the prior art device, it is easy to cause the driving wire 240 to break.

[0050] To solve the above technical problems, an embodiment of the present invention provides a conveying device for conveying a prosthesis with a movable part, comprising: a shell, a driving assembly, comprising a second movable part, the second movable part being movably accommodated in the shell relative to the shell along the axial direction of the shell; a wire fixing part, movably accommodated in the second movable part; a driving wire, the proximal end of the driving wire being fixed to the wire fixing part, and the distal end of the driving wire being used for detachably connecting the prosthesis; the second movable part drives the driving wire to move axially via the wire fixing part to drive the movable part of the prosthesis (in this embodiment, the clamping arm of the above-mentioned mitral valve clip) to move; a buffer, the buffer is located between the second movable part and the wire fixing part, and is used to apply pre-tightening forces in opposite directions to the second movable part and the wire fixing part respectively, so that the second movable part and the wire fixing part have a movement tendency to move away from each other; a limiting assembly, the limiting assembly is configured to prevent the wire fixing part from moving toward the proximal end under the action of the pre-tightening force.

[0051] Such an arrangement can prevent the drive wire and movable parts from being damaged during movement, or the human tissue and other parts of the prosthesis acted upon by the movable parts from being damaged. Specifically in this embodiment, the friction between the various components and parts in the mitral valve clip and the delivery device can be ignored. When the second movable part is moved toward the distal end, the clamp arm rotates and unfolds, and the distal end of the drive wire is not subjected to the force of the mitral valve clip. With the cooperation of the buffer and the limit assembly, the second movable part and the wire fixing part remain relatively stationary in the axial direction, and the wire fixing part moves toward the distal end with the second movable part. When the second movable part is moved toward the proximal end, and the mitral valve clip clamps the anterior and posterior petals, the anterior and posterior petals of the mitral valve are in contact with each other before clamping. The force of the clamp arm can be ignored, the force on the far end of the driving wire can be ignored, the second moving member and the wire fixing member remain relatively still in the axial direction, and the wire fixing member moves toward the proximal end as a whole with the second moving member; and after the second moving member continues to move toward the proximal end, and the mitral valve clip clamps the anterior and posterior flaps, as mentioned above, the clamp arm of the mitral valve clip can no longer continue to rotate, and the driving wire no longer moves toward the proximal end as a whole, but the far end of the driving wire is approximately fixed, and the proximal end of the driving wire moves toward the proximal end, so the tension of the driving wire gradually increases. When the tension of the driving wire is greater than the preload, the second moving member begins to move toward the proximal end relative to the wire fixing member, further squeezing the buffer. In the prior art, the deformation of the drive wire is the same as the axial displacement of the first moving member, and in the present embodiment, when the tension of the drive wire is greater than the preload, the wire fixing member is only subjected to the force exerted on it by the buffer member and the drive wire, and the force exerted on the buffer member by the second moving member is related to the elastic properties of the buffer member itself (for example, the Hooke's coefficient of the elastic member; for another example, the damping coefficient of the hydraulic buffer; for another example, the damping coefficient of the gas pressure buffer) and the axial displacement of the second moving member, therefore, the force exerted on the wire fixing member by the buffer member increases slowly as the second moving member squeezes the buffer member, thus, the tension of the drive wire also increases slowly, which can avoid leaflet damage or drive wire breakage; on the other hand, because the elastic properties of the buffer member itself are generally much smaller than the tensile modulus of the drive wire, therefore, the deformation of the drive wire produced by the force exerted on the drive wire by the wire fixing member (that is, the transmission of the force exerted on the wire fixing member by the buffer member) is much smaller than the axial displacement of the second moving member, which plays a good protective role on the drive wire.

[0052] The implementation details of the conveying device of this embodiment are described in detail below. The following content is only provided for easy understanding of the implementation details and is not necessary for implementing this solution.

[0053] See also Figures 6 to 8The embodiment of the present invention provides a delivery device 200 for the above-mentioned mitral valve clip 100. The delivery device 200 includes: a housing 210, a driving assembly including a second moving member 220, a wire fixing member 230, a buffer member 250 located between the second moving member 220 and the wire fixing member 230, a limiting assembly, and a driving wire 240.

[0054] The second moving member 220 is movably disposed in the housing 210 relative to the housing 210 along the axial direction of the housing 210. The wire fixing member 230 is movably accommodated in the second moving member 220.

[0055] The proximal end of the driving wire 240 is fixed to the wire fixing member 230, and the distal end of the driving wire 240 is used to detachably connect the mitral valve clip 100. The second moving member 220 drives the driving wire 240 to move axially via the wire fixing member 230 to drive the clip arm 120 of the mitral valve clip 100 to move.

[0056] The buffer member 250 located between the second moving member 220 and the wire fixing member 230 is used to apply preload forces in opposite directions to the second moving member 220 and the wire fixing member 230 respectively, so that the second moving member 220 and the wire fixing member 230 have a movement tendency to move away from each other.

[0057] The limiting assembly is configured to prevent the wire fixing member 230 from moving toward the proximal end of the second moving member 220 under the action of the preload force. Since the buffer member applies preload forces in opposite directions to the second moving member 220 and the wire fixing member 230, respectively, the second moving member 220 and the wire fixing member 230 have a tendency to move away from each other. However, due to the existence of the limiting assembly, the second moving member 220 and the wire fixing member 230 cannot move away from each other, and thus remain relatively still in the axial direction.

[0058] See also Figure 7 and Fig.11 The housing 210 includes a receiving space 211 , and a proximal opening 212 is provided at the proximal end of the housing 210 . The distal end of the second moving member 220 is disposed at the proximal end of the housing 210 through the proximal opening 212 and is received in the receiving space 211 .

[0059] See also Fig.11 and Fig.12, the drive assembly also includes a drive member 260, which is transmission-connected with the second mobile member 220 to transmit the operating force of the operator to the second mobile member 220 so that the second mobile member 220 moves axially. In one example, the drive member 260 is sleeved on the outer periphery of the second mobile member 220, the drive member 260 is provided with an internal thread 261, and the second mobile member 220 is provided with an external thread 222 that cooperates with the internal thread 261. The drive member 260 and the second mobile member 220 are threadedly connected, and the drive member 260 is configured to be rotatable relative to the shell 210 and axially stationary relative to the shell 210, and the second mobile member 220 is configured to be movable relative to the shell 210 and circumferentially stationary relative to the shell 210. In this way, the operator rotates the drive member 260, and the drive member 260 drives the second mobile member 220 to move axially.

[0060] Specifically, the driving member 260 includes a connecting passage 262 that runs through the front and rear end surfaces, the inner wall of the connecting passage 262 is provided with an internal thread 261, a part of the outer wall of the second moving member 220 is provided with an external thread 222, and after the distal end of the second moving member 220 passes through the connecting passage 262, the external thread 222 and the internal thread 261 cooperate with each other. In this way, the second moving member 220 and the driving member 260 constitute a screw slider transmission mechanism, and when the driving member 260 is rotated, the second moving member 220 can move axially relative to the housing 210. It can be understood that a travel limit is provided at the distal end of the external thread 222 to prevent the moving travel of the second moving member 220 from exceeding the limit.

[0061] See again Fig.11 and Fig.12 The edge of the proximal opening 212 is radially contracted to form an opening shoulder 213 , and a circumferentially extending limiting groove 263 is provided at the distal end of the driving member 260 , and the opening shoulder 213 is accommodated in the limiting groove 263 , so that the driving member 260 is restricted and can only rotate relative to the housing 210 .

[0062] The second moving member 220 can be moved relative to the shell 210 along the axial direction of the shell 210, and is circumferentially static relative to the shell 210. For example, the inwall of the shell 210 is provided with the first limiting member (not shown), and the outer surface of the far-end of the second moving member 220 is provided with the second limiting member (not shown), and the first limiting member is configured to limit the second limiting member circumferentially, so that the second moving member 220 can only be axially moved relative to the shell 210. Exemplary, the inside of the shell 210 can be provided with one or more axially extending chute, and the first limiting member is a chute, and the far-end outer surface of the second moving member 220 is provided with a protruding structure, and the second limiting member is a protruding structure. The protruding structure can be accommodated in the chute, and the protruding structure can move in the direction of the chute constraint. When the driving member 260 is rotated, the sidewall of the chute stops the protruding structure from rotating, thereby making the second moving member 220 unable to rotate circumferentially.

[0063] See again Figure 8 , the second moving member 220 is provided with a moving channel 221 in the axial direction. The distal end of the wire fixing member 230 is at least partially movably accommodated in the moving channel 221. On the whole, the outer diameter of the wire fixing member 230 is less than or equal to the diameter of the moving channel 221. In this way, the wire fixing member 230 can move axially relative to the second moving member 220. In one example, the moving channel 221 includes a first sub-channel 221a and a second sub-channel 221b, the first sub-channel 221a is located at the distal end side of the second sub-channel 221b, and the inner diameter of the first sub-channel 221a is less than the inner diameter of the second sub-channel 221b, so as to form a first abutting surface 221c at the connection between the first sub-channel 221a and the second sub-channel 221b. In this way, a step structure can be formed at the connection between the first sub-channel 221a and the second sub-channel 221b, because the first sub-channel 221a is located at the distal end side of the second sub-channel 221b, therefore, the step surface of the step structure faces the proximal end, forming the first abutting surface 221c. Exemplarily, the moving channel 221 axially penetrates the second moving member 220, the first sub-channel 221a and the second sub-channel 221b are both circular channels, and the inner diameter of the first sub-channel 221a is smaller than the inner diameter of the second sub-channel 221b. In addition, the moving channel 221 can also be an elliptical channel, a polygonal channel, etc., and the shape of the wire fixing member 230 can be appropriately adjusted to match the moving channel 221.

[0064] See also Fig. 9 Accordingly, the wire fixing member 230 includes a first section 231 located at the distal end and a second section 232 located at the proximal end, and the outer diameter of the first section 231 is smaller than the outer diameter of the second section 232, so as to form a second abutting surface 233 at the connection between the first section 231 and the second section 232. In this way, a step structure can be formed at the connection between the first section 231 and the second section 232. Since the first section 231 is located at the distal end side of the second section 232, the step surface of the step structure faces the distal end, forming the second abutting surface 233. Exemplarily, the first section 231 and the second section 232 are both cylindrical structures, and the outer diameter of the first section 231 is smaller than the outer diameter of the second section 232.

[0065] Further, the outer diameter of the first section 231 can be equal to or slightly smaller than the inner diameter of the first sub-channel 221a, and the outer diameter of the second section 232 can be equal to or slightly smaller than the inner diameter of the second sub-channel 221b, that is, the first section 231 can be accommodated in the first sub-channel 221a and the second sub-channel 221b, but the second section 232 part can only be accommodated in the second sub-channel 221b. In this way, the wire fixing member 230 can move axially relative to the second moving member 220. When the part of the first section 231 is arranged in the first sub-channel 221a, and the part of the second section 232 is arranged in the second sub-channel 221b, the second abutting surface 233 is located in the second sub-channel 221b, and is opposite to the first abutting surface 221c. At this time, the buffer 250 is disposed between the first abutting surface 221c and the second abutting surface 233. When the second moving member 220 and the wire fixing member 230 move toward each other to compress the buffer 250, the buffer 250 generates a force on the second moving member 220 and the wire fixing member 230. At this time, the buffer 250 is located in the second sub-channel 221b.

[0066] In an alternative example, the mobile passage 221 is no longer provided with the first sub-channel 221a and the second sub-channel 221b, and the proximal end face of the second moving member 220 is used as the abutment surface, i.e., the third abutment surface. At this time, the inner diameters of the mobile passage 221 are constant or continuously changed. Or, although the mobile passage 221 is provided with the first sub-channel 221a and the second sub-channel 221b, and the first abutment surface 221c formed by the first sub-channel 221a and the second sub-channel 221b, the first abutment surface 221c is no longer used to abut the buffer member 250. The wire fixing member 230 still includes a first section and a second section, wherein the outer diameter of the first section is smaller than the outer diameter of the second section, so as to form a second abutting surface 233 at the connection between the first section and the second section, the outer diameter of the first section 231 of the wire fixing member 230 is equal to or slightly smaller than the inner diameter of the moving channel 221, and the first section 231 is partially located in the moving channel 221, and the outer diameter of the second section 232 is larger than the outer diameter of at least the proximal end of the moving channel 221, so that the second section 232 is located on the proximal side of the second moving member 220 and is limited to the outside of the moving channel 221. The buffer member 250 is located between the third abutting surface and the second abutting surface 233, and can abut the third abutting surface and the second abutting surface 233. At this time, the buffer member 250 is located outside the moving channel 221. This embodiment has no particular restrictions on the specific structure of the limiting assembly.

[0067] See also Figure 6 , Figure 7 and Fig. 9In one example, the limit assembly includes a snap-on cover 270 and a limit member 223. The limit member 223 is disposed at the proximal end of the second movable member 220, and the snap-on cover 270 abuts against the proximal end of the wire fixing member 230, and is coupled to the limit member 223, so that the second movable member 220 and the wire fixing member 230 under the action of the preload force remain relatively stationary in the axial direction. For example, the snap-on cover 270 may be movably sleeved on the proximal end of the second movable member 220, and is coupled to the limit member 223, so that the second movable member 220 and the wire fixing member 230 under the action of the preload force remain relatively stationary in the axial direction.

[0068] In one example, the snap-on cover 270 comprises an abutment portion 271 and a first limiting portion 272 that are fixedly connected to each other. The abutment portion 271 is arranged at the proximal end of the first limiting portion 272, and is used to abut the proximal end of the wire fixing member 230, and the first limiting portion 272 is used to couple with the limiting member 223. In this way, the wire fixing member 230 is restricted to move to the proximal end under the preload force relative to the second moving member 220. Exemplary, the first limiting portion 272 and the limiting member 223 can be restricted by a clamping mode. Or, the first limiting portion 272 and the limiting member 223 can also adopt other connection modes, and the wire fixing member 230 is restricted to move to the proximal end under the preload force relative to the second moving member 220.

[0069] When assembling the second movable member 220, the wire fixing member 230, the buckling cover 270, the limiting member 223 and the buffer member 250, the buffer member 250 is first placed in the second sub-channel 221b, and the distal end of the buffer member 250 contacts the first abutting surface 221c; then the wire fixing member 230 is placed in the movable channel 221, and the proximal end of the buffer member 250 contacts the second abutting surface 233. In a natural state, the buffer member 250 maintains a natural length, and the proximal end of the wire fixing member 230 extends from the proximal end of the second movable member 220; the buckling cover 270 is made to abut and squeeze the proximal end of the wire fixing member 230, so that the wire fixing member 230 squeezes the buffer member 250 through the second abutting surface 233, and the buffer member 250 is compressed to generate a pre-tightening force until the buckling cover 270 is coupled with the limiting member 223. In this way, the buffer member 250 can be configured to be compressed until the pre-tightening force reaches a predetermined threshold value. At this time, due to the action of the buffer member 250 on the wire fixing member 230, the wire fixing member 230 has a tendency to move toward the proximal end of the second movable member 220. At the same time, due to the cooperation of the snap-fit ​​cover 270 and the limit member 223, the wire fixing member 230 is restricted from moving toward the proximal end of the second movable member 220, so that the wire fixing member 230 and the second movable member 220 remain relatively stationary axially.

[0070] Taking the first limiting portion 272 and the limiting member 223 being mutually engaged as an example, the snap-on cover 270 also includes a connecting portion 273 connecting the abutting portion 271 and the first limiting portion 272, and the connecting portion 273 is arranged circumferentially along the abutting portion 271 and extends axially. The first limiting portion 272 is located at an end of the connecting portion 273 away from the abutting portion 271. In one example, the first limiting portion 272 is a first protrusion extending radially toward the second moving member 220 (inwardly in the figure). Correspondingly, the limiting member 223 is a second protrusion extending radially away from the direction of the second moving member 220 (outwardly in the figure), and the first protrusion is engaged with the second protrusion so that the silk fixing member 230 and the second moving member 220 remain relatively static in the axial direction. "Radial" is a direction perpendicular to the axial direction.

[0071] See again Fig.10 The cooperation of the connecting portion 273 and the abutting portion 271 makes the snap-fit ​​cover 270 as a whole in a groove shape, which includes a cavity 274, and the cavity 274 is used to accommodate the proximal end of the second movable member 220 and the proximal end of the wire fixing member 230. The abutting portion 271 is the bottom of the groove, and the connecting portion 273 is the side wall of the groove. The first protrusion is arranged at one end of the connecting portion 273 away from the abutting portion 271. It can be understood that the circumferential size of the cavity 274 should be larger than the outer diameter of the proximal end of the second movable member 220 and larger than the outer diameter of the proximal end of the wire fixing member 230; the axial size of the cavity 274 will affect the size of the buffer 250 under pressure, that is, the size of the preload. Therefore, the axial size of the cavity 274, as a factor affecting the preload, will be adjusted according to the size of the preload as needed.

[0072] In one example, the connecting portion 273 is cylindrical; there may be a plurality of first protrusions, which are arranged on the connecting portion 273 at intervals along the circumference of the connecting portion 273. Alternatively, there may be only one first protrusion, which is extended along the circumference of the connecting portion 273.

[0073] In one example, the connecting portion 273 can be set to multiple, and the circumferential spacing around the abutting portion 271 is set. At the same time, each connecting portion 273 extends axially. At this time, the first limiting portion 272 is correspondingly set to multiple, and is arranged one by one at the far end of the first limiting portion 272 away from the abutting portion 271. For example, the connecting portion 273 is circumferentially set to multiple comb tooth structures. With such a configuration, when the second movable member 220 and the wire fixing member 230 are connected using the snap-fit ​​cover 270, each connecting portion 273 can better achieve elastic deformation, reducing the difficulty of assembly.

[0074] Continue to see Figure 8 and Fig.10, the first projection includes a first sliding surface 272a and a fourth abutting surface 272b, and the first sliding surface 272a is located at the distal end side of the fourth abutting surface 272b. The second projection includes a second sliding surface 223a and a fifth abutting surface 223b, and the second sliding surface 223a is located at the proximal end side of the fifth abutting surface 223b. For example, the first sliding surface 272a can be tilted, and the first sliding surface 272a gradually approaches the second moving member 220 from far to near, and the fourth abutting surface 272b is perpendicular to the axial direction or tilted in the same direction as the first sliding surface 272a; the second sliding surface 223a is tilted, and the second sliding surface 223a gradually moves away from the direction of the second moving member 220 from far to near, and the fifth abutting surface 223b is perpendicular to the axial direction or tilted in the same direction as the second sliding surface 223a. Preferably, the fourth abutting surface 272b and the fifth abutting surface 223b have the same degree of inclination.

[0075] When the buckle cover 270 is engaged with the stopper 223, the first sliding surface 272a can slide relative to the second sliding surface 223a until the fourth abutting surface 272b moves to the side of the fifth abutting surface 223b. Moreover, after the buckle cover 270 is engaged with the stopper 223, the fourth abutting surface 272b is configured to abut the fifth abutting surface 223b. With such a configuration, the first sliding surface 272a and the second sliding surface 223a can cooperate with each other, and the fourth abutting surface 272b and the fifth abutting surface 223b can cooperate with each other, so that the buckle cover 270 can be engaged with the stopper 223, thereby reducing the difficulty of assembly.

[0076] Optionally, in the cross section along the axial direction, the cross-sectional shape of the first protrusion may be a triangle or a trapezoid, and the cross-sectional shape of the second protrusion may also be a triangle or a trapezoid. Preferably, both the first protrusion and the second protrusion are right-angled triangles or right-angled trapezoids.

[0077] refer to Fig.13 In another alternative embodiment, the limiting assembly includes a slide groove 224 which is arranged at the proximal end of the second movable member 220 and extends axially, and a sliding portion 234 which is arranged at the proximal end of the wire fixing member 230, and the sliding portion 234 is movably arranged in the slide groove 224.

[0078] In one example, the sliding part 234 can be arranged on the side of the second section 232 of the wire fixing member 230, and the chute 224 is arranged on the sidewall of the second sub-channel 221b of the second moving member 220. Under the effect of the preload, there is a movement trend away from each other between the second moving member 220 and the wire fixing member 230, and because the sliding part 234 abuts the proximal side wall of the chute 224, the second moving member 220 and the wire fixing member 230 are kept relatively static in the axial direction. When the driving wire 240 tension force is greater than the preload, if the operator continues to operate the driving member 260, the second moving member 220 can move relative to the wire fixing member 230. At this time, the sliding part 234 moves to the far end relative to the chute 224. The application does not limit the number and specific shape of the chute 224 and the sliding part 234.

[0079] For example, there are multiple slide grooves 224 that are spaced apart along the circumference of the second movable member 220 ; there are multiple sliding portions 234 that are spaced apart along the circumference of the wire fixing member 230 ; at least one sliding portion 234 is accommodated in at least part of the slide grooves 224 .

[0080] In another alternative embodiment, similar to the above embodiment, the difference is that the limit assembly includes a second limit portion arranged on the second moving member 220 and a third limit portion arranged on the wire fixing member 230, and the buffer 250 is located between the second moving member 220 and the third limit portion, and the buffer 250 is used to apply a preload to the second moving member 220, and apply a preload to the wire fixing member 230 through the second limit portion, and the two preloads are the same in size and opposite in direction. In addition, the second limit portion and the third limit portion cooperate with each other to prevent the wire fixing member 230 from moving toward the proximal end under the action of the preload force it receives.

[0081] In one example, the second limiting portion can adopt the above-mentioned slide groove 224, and the third limiting portion can adopt the above-mentioned sliding portion 234. Further, in this example, the wire fixing member 230 may no longer be provided with the first section 231 and the second section 232, and there is no second abutting surface. That is, the size of the wire fixing member 230 remains unchanged or changes continuously, for example, it is approximately cylindrical or truncated cone-shaped. Alternatively, although the second abutting surface is formed between the first section 231 and the second section 232 in the wire fixing member 230, the second abutting surface is no longer used to abut the buffer member 250. The buffer member 250 is located between the first abutting surface 221c in the second movable member 220 and the distal end face of the sliding portion 234.

[0082] In this embodiment, the proximal end of the drive wire 240 is fixed to the wire fixing member 230, and the distal end passes through the housing 210 after passing through the accommodating space 211, and extends toward the distal end of the delivery device 200, and then detachably connects to the mitral valve clip 100. It should be noted that the drive wire 240 can preferably be a biocompatible metal wire, such as stainless steel, nickel titanium metal, etc. In addition, the distal end of the drive wire 240 can be provided with an external thread, and the proximal end of the base 141 can be provided with an internal thread that matches the external thread, and the drive wire 240 and the base 141 are detachably connected by thread. Alternatively, an internal thread can be provided at the distal end of the drive wire 240, and an external thread that matches the internal thread can be provided at the proximal end of the base 141, so that the drive wire 240 and the base 141 are threadedly connected. Alternatively, the distal end of the drive wire 240 can be provided with other coupling structures, and the proximal end of the base 141 can be provided with a structure that matches the coupling structure to connect or separate from the base 141.

[0083] The present embodiment has no particular restrictions on the specific type of the buffer 250, as long as it can generate a force when under pressure. For example, the buffer 250 can be an elastic member, a hydraulic buffer or a pneumatic buffer. Exemplarily, in a natural state, the buffer 250 drives the proximal end of the wire fixing member 230 to extend from the proximal end of the second moving member 220. When the buckle cover 270 abuts against the wire fixing member 230, the wire fixing member 230 is driven to move toward the distal end, and at the same time, the buffer 250 is forced to generate a pre-tightening force, and under the action of the pre-tightening force, the second moving member 220 and the wire fixing member 230 have a movement tendency away from each other; when the buckle cover 270 is coupled to the first limiting portion 272, the second moving member 220 and the wire fixing member 230 are kept axially relatively prohibited. Preferably, the buffer 250 is set as an elastic member, such as a rubber ring, a compression spring, etc. As the buffer 250, the elastic member can be directly sleeved on the wire fixing member 230. In this way, the buffer 250 has a simple structure and low assembly difficulty.

[0084] See again Figure 6 and Figure 7 The delivery device further includes a catheter 280, which extends from the housing 210 to the distal end of the delivery device. The catheter 280 is detachably connected to the base 110 of the mitral clip 100. This embodiment does not particularly limit the specific detachable connection between the two. The catheter 280 is also provided with an axially through delivery channel for the drive wire 240 to pass through.

[0085] The above is a detailed introduction to the conveying device provided in the embodiment of the present invention. Specific examples are used herein to illustrate the principle and implementation of the present invention. The description of the above implementation is only used to help understand the idea of ​​the present invention. There may be changes in the specific implementation and application scope. In summary, the content of this specification should not be understood as a limitation on the present invention.

Claims

1. A conveying device for conveying a prosthesis having a movable part, characterized in that: include: shell; A driving assembly, comprising a moving member, wherein the moving member is accommodated in the housing so as to be movable relative to the housing along the axial direction of the housing; a wire fixing member, the wire fixing member being movably accommodated in the moving member; A driving wire, the proximal end of which is fixed to the wire fixing member, and the distal end of which is used to be detachably connected to the prosthesis; the moving member drives the driving wire to move axially via the wire fixing member to drive the movable member to move; a buffer member, the buffer member being located between the moving member and the wire fixing member and being used for applying pre-tightening forces in opposite directions to the moving member and the wire fixing member respectively, so that the moving member and the wire fixing member have a tendency to move away from each other; A limiting assembly is configured to prevent the wire fixing member from moving toward the proximal end under the action of the pre-tightening force.

2. The conveying device according to claim 1, characterized in that The moving member includes an axially extending moving channel, the moving channel includes a first sub-channel and a second sub-channel, the first sub-channel is located at a distal end of the second sub-channel, and the inner diameter of the first sub-channel is smaller than the inner diameter of the second sub-channel, so as to form a first abutment surface at the connection between the first sub-channel and the second sub-channel; The wire fixing member includes a first section and a second section, the outer diameter of the first section is smaller than the outer diameter of the second section, so as to form a second abutment surface at the connection between the first section and the second section, the first section is partially accommodated in the first sub-channel, the second section is partially accommodated in the second sub-channel, and the buffer is located between the first abutment surface and the second abutment surface.

3. The conveying device according to claim 1, characterized in that: The moving member includes an axially extending moving channel, the end face of the proximal end of the moving member is defined as a first abutment surface, the wire fixing member includes a first section and a second section, the outer diameter of the first section is smaller than the outer diameter of the second section, so as to form a second abutment surface at the connection between the first section and the second section, the first section is partially accommodated in the moving channel, the second section is located on the proximal side of the moving member and is limited to outside the moving channel; the buffer member is located between the first abutment surface and the second abutment surface.

4. The conveying device according to claim 1 or 2, characterized in that: The limiting assembly includes a slide groove which is arranged at the proximal end of the moving member and extends axially, and a sliding portion which is arranged at the proximal end of the wire fixing member. The sliding portion is movably arranged in the slide groove to couple the moving member and the fixing member.

5. The conveying device according to claim 4, characterized in that: There are a plurality of slide grooves, which are spaced apart along the circumference of the movable member; there are a plurality of sliding parts, which are spaced apart along the circumference of the fixed member; and at least one sliding part is accommodated in at least a portion of the slide grooves.

6. The conveying device according to any one of claims 1 to 3, characterized in that: The limiting assembly includes a snap-fit ​​cover and a limiting member arranged at the proximal end of the moving member. The snap-fit ​​cover abuts against the proximal end of the wire fixing member and is coupled to the limiting member so that the moving member and the wire fixing member remain axially relatively still under the action of the preload force.

7. The conveying device according to claim 6, characterized in that The snap-on cover comprises an abutting portion and a limiting portion which are fixedly connected. The abutting portion is arranged at the proximal end of the limiting portion and is used to abut the proximal end of the wire fixing member. The limiting portion is used to couple with the limiting member.

8. The conveying device according to claim 7, characterized in that The snap-on cover also includes a connecting portion fixedly connecting the abutting portion and the limiting portion, wherein the connecting portion is arranged circumferentially along the abutting portion and extends axially; the limiting portion is located at one end of the connecting portion away from the abutting portion, and the limiting portion is used to be clamped with the limiting member.

9. The conveying device according to claim 8, characterized in that: The limiting portion is a first protrusion extending radially toward the moving member, and the limiting member is a second protrusion arranged along the circumference of the moving member and extending radially toward the buckle cover, the first protrusion includes a first sliding surface and a third abutting surface, and the first sliding surface is located at a distal end side of the third abutting surface; the second protrusion includes a second sliding surface and a fourth abutting surface, and the second sliding surface is located at a proximal end side of the fourth abutting surface; The first sliding surface is configured to slide relative to the second sliding surface when the snap-fit ​​cover is engaged with the limiting member; the third abutting surface is configured to abut against the fourth abutting surface after the snap-fit ​​cover is engaged with the limiting member.

10. The conveying device according to any one of claims 1 to 3, characterized in that: The buffer member is an elastic member, a hydraulic buffer or a pneumatic buffer.

11. The conveying device according to claim 10, characterized in that The elastic member is a compression spring or a rubber ring sleeved on the wire fixing member.

12. A conveying device for conveying a prosthesis having a movable part, characterized in that: include: shell; A driving assembly, comprising a moving member, wherein the moving member is accommodated in the housing so as to be movable relative to the housing along the axial direction of the housing; a wire fixing member, the wire fixing member being movably accommodated in the moving member; A driving wire, the proximal end of which is fixed to the wire fixing member, and the distal end of which is used to be detachably connected to the prosthesis; the moving member drives the driving wire to move axially via the wire fixing member to drive the movable member to move; A limiting assembly, comprising a first limiting portion provided on the moving member and a second limiting portion provided on the wire fixing member; a buffer, the buffer being located between the moving member and the second limiting portion, the buffer being used to apply a first pre-tightening force to the moving member, and to apply a second pre-tightening force to the wire fixing member through the second limiting portion, so that the moving member and the wire fixing member have a movement tendency to move away from each other, the first pre-tightening force and the second pre-tightening force being equal in magnitude and opposite in direction; The limiting assembly is configured to prevent the wire fixing piece from moving toward the proximal end under the action of the second pre-tightening force through the cooperation of the first limiting portion and the second limiting portion.

13. The conveying device according to claim 12, characterized in that: The first limiting portion is a slide groove which is arranged at the proximal end of the moving member and extends axially, and the second limiting portion is a sliding portion which is arranged at the proximal end of the wire fixing member, and the sliding portion is movably arranged in the slide groove.

14. The conveying device according to claim 13, characterized in that The moving member includes an axially extending moving channel, the moving channel includes a first sub-channel and a second sub-channel, the first sub-channel is located at a distal end of the second sub-channel, and the inner diameter of the first sub-channel is smaller than the inner diameter of the second sub-channel, so as to form a first abutment surface at the connection between the first sub-channel and the second sub-channel; The wire fixing member is accommodated in the moving channel, and the buffer member is located between the first abutting surface and the distal end surface of the sliding portion.

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