Drying box for immune globulin production

By using spiral blades and hot air suction technology in the rotating part in the drying box for immunoglobulin production, the cumbersome drying process in the immunoglobulin production is solved, efficient protein powder production is achieved, and the equipment structure is simplified.

CN119097933AInactive Publication Date: 2024-12-10HUANGSHAN RUNXIN TECH DEV CO LTD
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Patent Information

Application Number
CN202411436377.1
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-10-15
Publication Date
2024-12-10
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

The drying process in the existing immunoglobulin production is cumbersome and inefficient.

Method used

A drying box for immunoglobulin production is designed, and spiral blades are provided in the rotating part to dry the protein mixture through hot air suction, reducing the use of power components and reducing the volume of the equipment.

Benefits of technology

The efficient drying of the protein mixture is achieved, protein powder is obtained, the equipment structure is simplified and production efficiency is improved.

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Abstract

The invention discloses a drying box for immune globulin production, and relates to the technical field. The device comprises a tank body, a discharge port is formed in the bottom of the tank body, an opening is formed in the top of the tank body, a base is fixed to the bottom of the tank body, the tank body is vertically installed, and an end cover is installed on the opening in a sealed mode; at least one feeding pipe distributed along the tangential direction of the tank body is arranged on the side surface of the tank body; a rotating part is installed in the tank body, a grinding part is installed at the bottom of the rotating part, the bottom end of the rotating part is fixedly installed on an air inlet pipe, and the air inlet pipe is fixed to the discharging opening. The spiral blades are arranged in the rotating part, hot air is sucked into the rotating part through the rotating part, the hot air is discharged through the surface of the rotating part, and protein mixed liquid is dried, so that protein powder is obtained.
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Description

Technical Field

[0001] The invention belongs to the technical field, and in particular relates to a drying box for immunoglobulin production. Background Art

[0002] Immunoglobulin (Ig) refers to a globulin with antibody (Ab) activity or chemical structure, which is similar to antibody molecules. Immunoglobulin is a tetrapeptide chain structure composed of two identical light chains and two identical heavy chains connected by interchain disulfide bonds. Immunoglobulins are divided into five categories, namely immunoglobulin G (IgG), immunoglobulin A (IgA), immunoglobulin M (IgM), immunoglobulin D (IgD) and immunoglobulin E (IgE). Immunoglobulins require a drying oven during production and processing to achieve drying treatment. The drying process of existing equipment is cumbersome. Summary of the invention

[0003] The purpose of the present invention is to provide a drying box for immunoglobulin production, in which a spiral blade is provided in a rotating part. The rotating part can draw hot air into the interior of the rotating part and discharge it through the surface of the rotating part, thereby drying the protein mixture and obtaining protein powder, thereby solving the related problems raised in the background technology.

[0004] In order to solve the above technical problems, the present invention is achieved through the following technical solutions: The present invention is a drying box for immunoglobulin production, comprising a tank body, wherein the bottom of the tank body is provided with a discharge port, the top of the tank body is provided with an opening, a base is fixed to the bottom of the tank body, the tank body is vertically installed, and an end cover is sealed and installed on the opening; at least one feed pipe distributed along the tangent direction of the tank body is provided on the side of the tank body; a rotating part is installed in the tank body, a grinding part is installed at the bottom of the rotating part, the bottom end of the rotating part is fixedly installed on an air inlet pipe, and the air inlet pipe is fixed at the discharge port.

[0005] Furthermore, the rotating part includes a top frame, a push plate, gauze, a column and a bottom frame, the top frame and the bottom frame are both installed on the column, the end of the top frame extending outward and the end of the bottom frame extending outward are connected by a push plate, and gauze is installed on two opposite ends of the frame formed by the top frame, the push plate and the bottom frame, and the cavity formed by the two relatively distributed gauzes is connected to the inside of the column through the slots.

[0006] Furthermore, the rotating part includes a top frame, a push plate, gauze, an elastic rod, a column and a bottom frame, and the top frame and the bottom frame have exactly the same structural features. A guide groove is opened on the side of the top frame, and the top frame and the bottom frame are both fixed on the column. The outer end of the top frame is connected to the outer end of the relatively distributed bottom frame through a push plate, and the push plate is provided with a protrusion that moves along the guide groove; both side edges of the push plate are connected to the column through elastic rods, and gauze is installed on the frame formed by the push plate and the elastic rod, and the cavity formed by the two relatively distributed gauzes is connected to the inside of the column through the slots.

[0007] Furthermore, a protrusion that contacts the push plate is provided on the inner wall of the tank body.

[0008] Furthermore, the upper side surface of the grinding portion is an inclined surface, and the grinding surface provided on the grinding portion matches the conical surface of the bottom of the tank body.

[0009] Furthermore, the grinding part is a hollow structure, the grinding part is connected with the inside of the column, and a through hole is provided on the lower side of the grinding part.

[0010] Furthermore, the air inlet pipe includes a bend and a connecting plate, the connecting plate is installed on the vertical section of the bend, the connecting plate is fixedly installed on the discharge port, and the bend is connected to the column.

[0011] Furthermore, a nozzle is installed in the feed pipe.

[0012] Furthermore, the nozzle is a tube body with one end closed, a strip groove is opened on the closed end of the tube body, and an impeller is rotatably installed in the tube body.

[0013] The present invention has the following beneficial effects: 1. The protein mixture sprayed out from the feed pipe of the present invention adheres to the surface of the rotating part, and the rotating part is provided with spiral blades. The rotating part can draw hot air into the interior of the rotating part and discharge it through the surface of the rotating part to dry the protein mixture, thereby obtaining protein powder, reducing the use of power components, and effectively reducing the volume of the equipment.

[0014] 2. The protein mixture sprayed from the feed pipe of the present invention adheres to the gauze and pushes the rotating part to rotate. In addition, the gauze has a rough surface and strong moisture absorption capacity, which facilitates the adhesion of the protein mixture.

[0015] 3. Both sides of the push plate of the present invention are connected to the column through elastic rods, and gauze is installed on the frame formed by the push plate and the elastic rods. When the push plate reciprocates along the guide groove, the elastic rods are straightened and bent, thereby driving the installed gauze to vibrate, so as to facilitate the shaking and collection of the dried protein powder.

[0016] 4. The push plate provided in the present invention is squeezed and vibrated by the provided protrusion, which is convenient for driving the gauze to collect the protein after drying.

[0017] Of course, any product implementing the present invention does not necessarily need to achieve all of the advantages described above at the same time. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the accompanying drawings required for describing the embodiments will be briefly introduced below. Obviously, the accompanying drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other accompanying drawings can be obtained based on these accompanying drawings without paying creative work.

[0019] Figure 1 It is a schematic diagram of the overall structure of the present invention; Figure 2 It is a schematic diagram of the overall cross-sectional structure of the present invention; Figure 3 It is a schematic diagram of the internal structure of the present invention; Figure 4 It is a schematic diagram of the cross-sectional structure of the integral rotating part of the present invention; Figure 5 It is a schematic diagram of the tank structure of the present invention; Figure 6 It is a schematic diagram of the nozzle structure of the present invention.

[0020] In the accompanying drawings, the components represented by the reference numerals are listed as follows: 1-tank body, 11-discharge port, 12-opening, 2-base, 3-end cover, 4-feeding pipe, 5-nozzle, 51-tube body, 52-strip groove, 53-impeller, 6-rotating part, 61-top frame, 611-guide groove, 62-push plate, 63-gauze, 64-elastic rod, 65-column, 651-slot hole, 66-base frame, 7-grinding part, 8-inlet pipe, 81-bend pipe, 82-connecting plate. DETAILED DESCRIPTION

[0021] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0022] In the description of the present invention, it should be understood that the terms "opening", "upper", "lower", "thickness", "top", "middle", "length", "inside", "all around" and the like indicating orientation or positional relationship are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the components or elements referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as limiting the present invention. Example

[0023] like Figure 1-3 As shown in Figures 5-6, the present invention is a drying oven for immunoglobulin production, comprising a tank body 1, the bottom of the tank body 1 having a discharge port 11, the top of the tank body 1 having an opening 12, a base 2 fixed to the bottom of the tank body 1, the tank body 1 is vertically installed, and an end cover 3 is sealed on the opening 12; at least one feed pipe 4 distributed along the tangential direction of the tank body 1 is provided on the side of the tank body 1; a rotating part 6 is installed in the tank body 1, a grinding part 7 is installed at the bottom of the rotating part 6, the bottom end of the rotating part 6 is fixedly installed on the air inlet pipe 8, and the air inlet pipe 8 is fixed at the discharge port 11.

[0024] The protein mixture sprayed out from the feed pipe 4 adheres to the surface of the rotating part 6, and the rotating part 6 is provided with spiral blades. The rotating rotating part 6 can draw hot air into the interior of the rotating part 6 and discharge it through the surface of the rotating part 6 to dry the protein mixture, thereby obtaining protein powder, reducing the use of power components, and effectively reducing the size of the equipment.

[0025] The rotating part 6 includes a top frame 61, a push plate 62, a gauze 63, an elastic rod 64, a column 65 and a bottom frame 66. The top frame 61 and the bottom frame 66 have the same structural features. A guide groove 611 is provided on the side of the top frame 61. The top frame 61 and the bottom frame 66 are both fixed on the column 65. The outer end of the top frame 61 is connected to the outer end of the bottom frame 66 which is arranged oppositely via the push plate 62. The push plate 62 is provided with a protrusion which moves along the guide groove 611. Both sides of the push plate 62 are connected to the column 65 through elastic rods 64. Gauze 63 is installed on the frame formed by the push plate 62 and the elastic rods 64. The cavity formed by the two relatively distributed gauze 63 is connected to the inside of the column 65 through the slots 651.

[0026] Both sides of the push plate 62 are connected to the column 65 through elastic rods 64. Gauze 63 is installed on the frame formed by the push plate 62 and the elastic rods 64. During the reciprocating motion of the push plate 62 along the guide groove 611, the elastic rods 64 are straightened and bent, thereby driving the installed gauze 63 to vibrate, so as to facilitate the shaking and collection of the dried protein powder.

[0027] The inner wall of the tank body 1 is provided with a protrusion that contacts the push plate 62 .

[0028] The push plate 62 is squeezed and vibrated by the protrusion, so as to drive the gauze 63 to collect the protein after drying.

[0029] The upper side surface of the grinding part 7 is an inclined surface, and the grinding surface provided on the grinding part 7 matches the conical surface of the bottom of the can body 1.

[0030] The rotating part 6 drives the grinding part 7 to rotate, and the grinding surface of the grinding part 7 is pressed against the conical surface at the bottom of the tank body 1 to grind the clumped proteins.

[0031] The grinding part 7 is a hollow structure, and the grinding part 7 is connected with the inside of the column 65. A through hole is provided on the lower side of the grinding part 7.

[0032] After the hot air enters the grinding part 7, the grinding part 7 is heated, and the protein is dried during the grinding process of the grinding part 7, thereby improving the looseness of the protein powder.

[0033] The air inlet pipe 8 includes a bend pipe 81 and a connecting plate 82 . The connecting plate 82 is installed on the vertical section of the bend pipe 81 . The connecting plate 82 is fixedly installed on the discharge port 11 . The bend pipe 81 is in communication with the column 65 .

[0034] A nozzle 5 is installed in the feed pipe 4 .

[0035] The nozzle 5 is a tube body 51 with one end closed. A strip groove 52 is formed on the closed end of the tube body 51 . An impeller 53 is rotatably installed in the tube body 51 .

[0036] The provided nozzle 5 facilitates the atomization of the protein mixture and makes it adhere evenly to the gauze 63, so as to facilitate drying. Example

[0037] like Figure 1-2 As shown in Figures 4-6, the present invention is a drying oven for immunoglobulin production, comprising a tank body 1, the bottom of the tank body 1 having a discharge port 11, the top of the tank body 1 having an opening 12, a base 2 fixed to the bottom of the tank body 1, the tank body 1 is vertically installed, and an end cover 3 is sealed on the opening 12; at least one feed pipe 4 distributed along the tangential direction of the tank body 1 is provided on the side of the tank body 1; a rotating part 6 is installed in the tank body 1, a grinding part 7 is installed at the bottom of the rotating part 6, the bottom end of the rotating part 6 is fixedly installed on the air inlet pipe 8, and the air inlet pipe 8 is fixed at the discharge port 11.

[0038] The protein mixture sprayed out from the feed pipe 4 adheres to the surface of the rotating part 6, and the rotating part 6 is provided with spiral blades. The rotating rotating part 6 can draw hot air into the interior of the rotating part 6 and discharge it through the surface of the rotating part 6 to dry the protein mixture, thereby obtaining protein powder, reducing the use of power components, and effectively reducing the size of the equipment.

[0039] The rotating part 6 includes a top frame 61, a push plate 62, gauze 63, a column 65 and a bottom frame 66. The top frame 61 and the bottom frame 66 are both installed on the column 65. The end of the top frame 61 extending outward and the end of the bottom frame 66 extending outward are connected by the push plate 62. Gauze 63 is installed on two opposite ends of the frame formed by the top frame 61, the push plate 62 and the bottom frame 66. The cavity formed by the two relatively distributed gauze 63 is connected to the inside of the column 65 through the slot 651.

[0040] The protein mixture sprayed from the feed pipe 4 adheres to the gauze 63, and at the same time, pushes the rotating part 6 to rotate. In addition, the gauze 63 has a rough surface and a strong moisture absorption capacity, which facilitates the adhesion of the protein mixture.

[0041] The inner wall of the tank body 1 is provided with a protrusion that contacts the push plate 62 .

[0042] The push plate 62 is squeezed and vibrated by the protrusion, so as to drive the gauze 63 to collect the protein after drying.

[0043] The upper side surface of the grinding part 7 is an inclined surface, and the grinding surface provided on the grinding part 7 matches the conical surface of the bottom of the can body 1.

[0044] The rotating part 6 drives the grinding part 7 to rotate, and the grinding surface of the grinding part 7 is pressed against the conical surface at the bottom of the tank body 1 to grind the clumped proteins.

[0045] The grinding part 7 is a hollow structure, and the grinding part 7 is connected with the inside of the column 65. A through hole is provided on the lower side of the grinding part 7.

[0046] After the hot air enters the grinding part 7, the grinding part 7 is heated, and the protein is dried during the grinding process of the grinding part 7, thereby improving the looseness of the protein powder.

[0047] The air inlet pipe 8 includes a bend pipe 81 and a connecting plate 82 . The connecting plate 82 is installed on the vertical section of the bend pipe 81 . The connecting plate 82 is fixedly installed on the discharge port 11 . The bend pipe 81 is in communication with the column 65 .

[0048] A nozzle 5 is installed in the feed pipe 4 .

[0049] The nozzle 5 is a tube body 51 with one end closed. A strip groove 52 is formed on the closed end of the tube body 51 . An impeller 53 is rotatably installed in the tube body 51 .

[0050] The provided nozzle 5 facilitates the atomization of the protein mixture and makes it adhere evenly to the gauze 63, so as to facilitate drying.

[0051] In the description of this specification, the description with reference to the terms "one embodiment", "example", "specific example", etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic representation of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable manner.

[0052] The preferred embodiments of the present invention disclosed above are only used to help illustrate the present invention. The preferred embodiments do not describe all the details in detail, nor do they limit the invention to the specific implementation methods described. Obviously, many modifications and changes can be made according to the content of this specification. This specification selects and specifically describes these embodiments in order to better explain the principles and practical applications of the present invention, so that those skilled in the art can understand and use the present invention well. The present invention is limited only by the claims and their full scope and equivalents.

Claims

1. A drying oven for immunoglobulin production, comprising a tank (1), characterized in that: The bottom of the tank body (1) is provided with a discharge port (11), the top of the tank body (1) is provided with an opening (12), a base (2) is fixed to the bottom of the tank body (1), the tank body (1) is installed vertically, and an end cover (3) is sealedly installed on the opening (12); At least one feed pipe (4) is provided on the side of the tank body (1) and is distributed along the tangential direction of the tank body (1); A rotating part (6) is installed in the tank body (1), a grinding part (7) is installed at the bottom of the rotating part (6), the bottom end of the rotating part (6) is fixedly mounted on an air inlet pipe (8), and the air inlet pipe (8) is fixed at a discharge port (11).

2. A drying oven for immunoglobulin production according to claim 1, characterized in that: The rotating part (6) comprises a top frame (61), a push plate (62), gauze (63), a column (65) and a bottom frame (66); the top frame (61) and the bottom frame (66) are both mounted on the column (65); an end portion of the top frame (61) extending outward and an end portion of the bottom frame (66) extending outward are connected via the push plate (62); gauze (63) is mounted on two opposite ends of a frame formed by the top frame (61), the push plate (62) and the bottom frame (66); a cavity formed by two oppositely distributed gauze (63) is connected to the interior of the column (65) via a slotted hole (651).

3. A drying oven for immunoglobulin production according to claim 1, characterized in that: The rotating part (6) comprises a top frame (61), a push plate (62), gauze (63), an elastic rod (64), a column (65) and a bottom frame (66); the top frame (61) and the bottom frame (66) have completely the same structural features; a guide groove (611) is provided on the side of the top frame (61); the top frame (61) and the bottom frame (66) are both fixed on the column (65); the outer end of the top frame (61) is connected to the outer end of the bottom frame (66) arranged opposite to it via the push plate (62); the push plate (62) is provided with a protrusion that moves along the guide groove (611); Both sides of the push plate (62) are connected to the column (65) via elastic rods (64); a gauze (63) is installed on the frame formed by the push plate (62) and the elastic rods (64); and a cavity formed by two oppositely distributed gauze (63) is connected to the interior of the column (65) via slots (651).

4. A drying oven for immunoglobulin production according to claim 2 or 3, characterized in that: The inner wall of the tank body (1) is provided with a protrusion that contacts the push plate (62).

5. A drying oven for immunoglobulin production according to claim 2 or 3, characterized in that: The upper side surface of the grinding portion (7) is an inclined surface, and the grinding surface provided on the grinding portion (7) cooperates with the conical surface of the bottom of the tank body (1).

6. A drying oven for immunoglobulin production according to claim 5, characterized in that: The grinding portion (7) is a hollow structure; the grinding portion (7) is connected to the interior of the column (65); and a through hole is provided on the lower side of the grinding portion (7).

7. A drying oven for immunoglobulin production according to claim 5, characterized in that: The air inlet pipe (8) comprises a curved pipe (81) and a connecting plate (82); the connecting plate (82) is mounted on a vertical section of the curved pipe (81); the connecting plate (82) is fixedly mounted on a discharge port (11); and the curved pipe (81) is in communication with a column (65).

8. A drying oven for immunoglobulin production according to claim 1, characterized in that: A nozzle (5) is installed in the feed pipe (4).

9. A drying oven for immunoglobulin production according to claim 8, characterized in that: The nozzle (5) is a tube body (51) with one end closed, a strip groove (52) is provided on the closed end of the tube body (51), and an impeller (53) is rotatably mounted inside the tube body (51).