Coagulated blood collection tube capable of adjusting anticoagulant dosage according to HCT and use method thereof

Abstract

The invention relates to the technical field of medical apparatus and instruments, and discloses a coagulated blood collection tube capable of adjusting anticoagulant dosage according to HCT and a use method thereof, the coagulated blood collection tube comprises a tube body and a tube cap arranged at the top of the tube body; a plurality of placement cavities are formed in the top in the tube body and are independent cavities, drainage openings are formed in the bottoms of the placement cavities, plastic bags are placed in the placement cavities and are filled with anticoagulants, a cutting mechanism is rotationally arranged on the tube cap, scales are arranged on the top surface of the tube cap in the circumferential direction, and the drainage openings are communicated with the drainage openings. The cutting mechanism comprises a rotating sleeve extending into the pipe cap, a tool rest arranged on the outer surface of the rotating sleeve and a tool fixed to the tool rest, a scale pointer is arranged on the top face of the rotating sleeve, and the rotating sleeve drives the tool to rotate to cut the plastic bag, so that the anticoagulant in the plastic bag enters the pipe body along the drainage opening, and the anticoagulant in the pipe body is cut. The device can add a corresponding amount of anticoagulant according to the HCT of a patient, so that the accuracy of a blood test result is improved.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a blood coagulation collection tube capable of adjusting the anticoagulant dosage according to HCT and a method for using the same. Background Art

[0002] Vacuum blood collection tubes are blood collection tubes that use vacuum negative pressure with blood collection needles. Vacuum blood collection tubes are divided into many types according to whether they contain anticoagulants and procoagulants, and what kind of substances they contain. Different types of blood collection tubes are used for different blood projects. For example, the red-capped serum tube does not contain any substance, it is just a vacuum; the blue-capped sodium citrate tube contains the anticoagulant sodium citrate and can be used for coagulation experiments; the green-capped heparin tube contains sodium heparin, etc., which is used for biochemical experiments such as liver function, kidney function, blood lipids, and blood sugar; there are also gray-capped potassium oxalate / sodium fluoride tubes and purple-capped EDTA (ethylenediaminetetraacetic acid) anticoagulant tubes.

[0003] The anticoagulant used for coagulation test is trisodium citrate hydrate (Na3C6H5O7·2H20, hereinafter referred to as sodium citrate), with a concentration of 105mmol / L~109mmol / L (3.1%~3.2%, usually 3.2%).

[0004] The volume ratio of blood to sodium citrate anticoagulant in conventional blood collection tubes should be 9:1. However, for high altitude areas, the incidence of high altitude polycythemia can reach 25.8% (statistics of migrant population aged 15-45 in Ali region). Secondly, in plain areas, HCT (hematocrit) of patients with primary polycythemia and some congenital heart diseases is higher than 55%. When the patient's hematocrit value is greater than 55%, the patient's blood collection volume and the final concentration of sodium citrate need to be adjusted to obtain the true coagulation test results. If no adjustment is made, the patient's APTT (activated partial thromboplastin time) and PT (prothrombin time) will be falsely prolonged, causing misdiagnosis of the patient and even leading to life-threatening excessive plasma transfusion. Therefore, adjusting the anticoagulant according to the HCT value is an important step before blood collection for clinical diagnosis and treatment of such patients.

[0005] However, there are currently no blood collection tubes that can automatically adjust the anticoagulant dosage. Generally, the laboratory uses a formula to quantitatively suck out the anticoagulant in the blood collection tube, leaving an appropriate amount of anticoagulant. However, after this operation, the blood collection tube is no longer a vacuum, and blood needs to be collected with a syringe and then injected into the blood collection tube. This process will cause some coagulation factors to be activated, bringing certain risks to the authenticity of the test results. At the same time, there are also biosafety risks caused by blood leakage, and the operation is cumbersome, which increases the workload of blood collection staff. Summary of the invention

[0006] The present application provides a coagulation blood collection tube capable of adjusting the anticoagulant dosage according to HCT, so as to solve the problem that the existing vacuum blood collection tube cannot adjust the amount of anticoagulant added according to the patient's hematocrit value, resulting in untrue coagulation test results.

[0007] In order to solve the above technical problems, the present application provides a coagulation blood collection tube with an anticoagulant dosage adjustable according to HCT, comprising: a tube body and a tube cap arranged on the top of the tube body; characterized in that a plurality of placement cavities are arranged on the top of the tube body, the plurality of placement cavities are independent cavities, a drainage port is arranged at the bottom of the plurality of placement cavities, plastic bags are placed in the plurality of placement cavities, the plastic bags are filled with anticoagulant, a cutting mechanism is rotatably arranged on the tube cap, a scale is circumferentially arranged on the top surface of the tube cap, the cutting mechanism comprises a rotating sleeve extending into the tube cap, a tool holder arranged on the outer surface of the rotating sleeve, and a tool fixed on the tool holder, a scale pointer is arranged on the top surface of the rotating sleeve, the rotating sleeve drives the tool to rotate and cut the plastic bag, so that the anticoagulant in the plastic bag enters the tube body along the drainage port.

[0008] In some embodiments of the present application, the outer wall of the tube body is vertically provided with scales.

[0009] In some embodiments of the present application, the number of the placement cavities is set to 27.

[0010] In some embodiments of the present application, the capacity of the anticoagulant in the plastic bag is 5.6 ul.

[0011] In some embodiments of the present application, 100 ul of citric acid is pre-placed at the bottom of the tube body.

[0012] In some embodiments of the present application, a stirring rod is provided on the tube cap, and the stirring rod is L-shaped, with the horizontal portion of the stirring rod extending to the outside of the tube cap and the vertical portion of the stirring rod extending from the top of the tube cap into the tube body.

[0013] In some embodiments of the present application, a base is provided at the bottom of the tube body, a handle is provided on one side of the base, a clamp is rotatably connected to the top of the handle, a latch is provided at the connecting end of the clamp, and the latch is used to limit the opening and closing of the clamp.

[0014] In some embodiments of the present application, the initial position of the scale pointer points to the 82% scale line of the scale.

[0015] In some embodiments of the present application, a method for using a blood coagulation collection tube capable of adjusting the anticoagulant dosage according to HCT is provided, wherein the specific steps of the method are as follows: Step 1, pre-place a tube solvent in the tube body according to the application scenario, and centrifuge the tube solvent, place the required solvent packaged in a plastic bag in the placement cavity as required, install the cutting mechanism in the center of the tube cap, and install the tube cap on the top of the tube body, and absorb the air in the tube body through a needle;

[0016] Step 2: The blood collection object is collected through the blood collection needle. The blood collection needle is inserted into the blood collection site, and the blood delivery needle is inserted into the tube body through the puncture port and the rubber stopper. The blood is pumped into the vacuum tube in a jet-like manner. When the amount of blood is sufficient, the staff pulls the blood delivery needle out of the vacuum tube and the blood collection needle out of the blood collection site.

[0017] Step 3: By confirming the patient's hematocrit (%) and blood collection volume, according to the formula C = (1.85 × 10 -3 )×(100-HCT)×V to determine the amount of anticoagulant added, where C refers to the volume of sodium citrate solution in mL; V refers to the blood collection volume in mL; HCT is the hematocrit (%). The rotating sleeve drives the knife holder and the knife to cut through several plastic bags, so that the anticoagulant in the plastic bag enters the tube body along the drainage port, and the amount of anticoagulant added is determined by the position of the scale pointer.

[0018] Step 4: Turn the tube upside down to fully mix the blood and solvent, perform centrifugation according to the requirements of the coagulation test, and obtain the plasma.

[0019] Compared with the prior art, the present invention has the following characteristics and beneficial effects:

[0020] The present invention is suitable for patients with HCT greater than 55%. By arranging a placement cavity on the tube cap, the anticoagulant can be placed on the top of the tube body first, and the anticoagulant can be accurately added after the patient's hematocrit value is determined. By arranging a cutting mechanism, the anticoagulant can be added without destroying the vacuum in the tube. By setting a scale pointer, the accuracy of anticoagulant addition is guaranteed, which solves the dilemma that the current quantitative anticoagulant in the coagulation blood collection tube is not suitable for patients with HCT higher than 55%. The device can add a corresponding amount of anticoagulant according to the patient's hematocrit value, thereby improving the accuracy of blood test results. At the same time, the assembled structure enables the cutting mechanism and the tube cap to be recycled, which has certain economic benefits and can produce better results if promoted and used. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 It is a schematic diagram of the overall structure of an embodiment of the present invention;

[0022] Figure 2 is a top view schematic diagram of a pipe cap according to an embodiment of the present invention;

[0023] Figure 3 It is a schematic structural diagram of another embodiment of the present invention;

[0024] Figure 4 It is a structural diagram of yet another embodiment of the present invention.

[0025] In the figure, 100, tube body; 200, tube cap; 210, placement cavity; 220, drainage port; 230, plastic bag; 300, cutting mechanism; 310, rotating sleeve; 320, tool holder; 330, tool; 340, scale pointer; 400, stirring rod; 500, base; 600, handle; 610, clamp. DETAILED DESCRIPTION

[0026] The specific implementation of the present invention is further described in detail below in conjunction with the accompanying drawings and examples. The following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention.

[0027] In the description of the present application, it should be understood that the terms "center", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc., indicating orientations or positional relationships, are based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present application.

[0028] The terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of the features. In the description of this application, unless otherwise specified, "plurality" means two or more.

[0029] In the description of this application, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to specific circumstances.

[0030] like Figure 1 and 2As shown, according to some embodiments of the present application, a blood collection tube with an anticoagulant dosage adjustable according to HCT comprises: a tube body 100 and a tube cap 200 disposed on the top of the tube body 100; a plurality of placement cavities 210 are disposed on the top of the tube body 100, the plurality of placement cavities 210 are independent cavities, a drainage port 220 is disposed at the bottom of the plurality of placement cavities 210, a plastic bag 230 is disposed in each of the plurality of placement cavities 210, the plastic bag 230 is filled with an anticoagulant, and a rotationally disposed on the tube cap 200 There is a cutting mechanism 300, and the top surface of the tube cap 200 is circumferentially provided with scales. The cutting mechanism 300 includes a rotating sleeve 310 extending into the tube cap 200, a tool holder 320 arranged on the outer surface of the rotating sleeve 310, and a tool 330 fixed on the tool holder 320. A scale pointer 340 is arranged on the top surface of the rotating sleeve 310. The rotating sleeve 310 drives the tool 330 to rotate and cut the plastic bag 230, so that the anticoagulant in the plastic bag 230 enters the tube body 100 along the drainage port 220.

[0031] According to some embodiments of the present application, the outer wall of the tube body 100 is vertically provided with scales, mainly for quickly reading the amount of blood collected, and then adding an appropriate amount of anticoagulant according to the amount of blood collected.

[0032] According to some embodiments of the present application, the number of placement cavities 210 is set to 27, mainly to control the total amount of anticoagulant and determine the maximum preset amount of anticoagulant according to the maximum blood sampling value.

[0033] According to some embodiments of the present application, the capacity of the anticoagulant in the plastic bag 230 is 5.6ul. Every time a plastic bag 230 is cut, the amount of anticoagulant in the tube body 100 increases by 5.6ul. The HCT value ranges from 55-81%. When collecting blood, you only need to turn the blood collection cap scale clockwise to the corresponding scale to obtain the correct anticoagulant volume.

[0034] According to some embodiments of the present application, 100 ul of citric acid is pre-placed at the bottom of the tube body 100 .

[0035] According to some embodiments of the present application, a method for using a coagulation blood collection tube capable of adjusting the anticoagulant dosage according to HCT is provided, and the specific steps of the method are as follows: Step 1, pre-place a tube solvent in the tube body 100 according to the application scenario, and centrifuge the tube solvent, place the required solvent packaged in a plastic bag 230 in the placement cavity 210 as needed, install the cutting mechanism 300 in the center of the tube cap 200, and install the tube cap 200 on the top of the tube body 100, and absorb the air in the tube body 100 through a needle;

[0036] Step 2: The blood collection object is collected through the blood collection needle. The blood collection needle is inserted into the blood collection site. The blood delivery needle is inserted into the tube body 100 through the puncture port and the rubber stopper. The blood is pumped into the vacuum tube in a jet-like manner. When the amount of blood is sufficient, the staff member pulls the blood delivery needle out of the vacuum tube and the blood collection needle out of the blood collection site.

[0037] Step 3: By confirming the patient's hematocrit (%) and blood collection volume, according to the formula C = (1.85 × 10 -3 )×(100-HCT)×V to determine the amount of anticoagulant added, wherein C refers to the volume of the sodium citrate solution in mL; V refers to the amount of blood collected in mL; HCT is the hematocrit (%), the rotating sleeve (310) is rotated to drive the knife holder (320) and the knife (330) to cut through a plurality of plastic bags (230), so that the anticoagulant in the plastic bags (230) enters the tube body (100) along the drainage port (220), and the amount of anticoagulant added is determined by the position of the scale pointer (340);

[0038] Step 4: Turn the tube 100 upside down to fully mix the blood and the solvent, perform centrifugation according to the requirements of the coagulation test, and obtain the plasma.

[0039] like Figure 4 As shown, in this embodiment, the difference is that a stirring rod 400 is provided on the tube cap 200, and the stirring rod 400 is arranged in an L shape. The horizontal part of the stirring rod 400 extends to the outside of the tube cap 200, and the vertical part of the stirring rod 400 extends from the top of the tube cap 200 to the inside of the tube body 100. When placing the stirring rod 400, ensure that the bottom end of the stirring rod 400 does not contact the inner bottom surface of the tube body 100, and the side of the stirring rod 400 does not contact the side wall of the tube body 100. The function of the stirring rod 400 is to accelerate the uniform fusion of the liquid.

[0040] In this embodiment, the specific steps are as follows: Step 1, pre-place a solvent in the tube body 100 according to the application scenario, and centrifuge the solvent in the tube, place the required solvent packaged in the plastic bag 230 in the placement cavity 210 as needed, install the cutting mechanism 300 at the center of the tube cap 200, and install the tube cap 200 on the top of the tube body 100, and absorb the air in the tube body 100 through the needle;

[0041] Step 2: The blood collection object is collected through the blood collection needle. The blood collection needle is inserted into the blood collection site. The blood delivery needle is inserted into the tube body 100 through the puncture port and the rubber stopper. The blood is pumped into the vacuum tube in a jet-like manner. When the amount of blood is sufficient, the staff member pulls the blood delivery needle out of the vacuum tube and the blood collection needle out of the blood collection site.

[0042] Step 3: By confirming the patient's hematocrit (%) and blood collection volume, according to the formula C = (1.85 × 10 -3)×(100-HCT)×V to determine the amount of anticoagulant added, wherein C refers to the volume of the sodium citrate solution in mL; V refers to the amount of blood collected in mL; HCT is the hematocrit (%), the rotating sleeve (310) is rotated to drive the knife holder (320) and the knife (330) to cut through a plurality of plastic bags (230), so that the anticoagulant in the plastic bags (230) enters the tube body (100) along the drainage port (220), and the amount of anticoagulant added is determined by the position of the scale pointer (340);

[0043] Step 4, rotate the rotating sleeve 310 to the 82% scale line of the cover body scale, rotate the stirring rod 400 within the track of the rotating sleeve 310 to fully mix the blood and the solvent, perform centrifugation according to the requirements of the coagulation test, and obtain the plasma.

[0044] like Figure 3 As shown, in this embodiment, the difference lies in that a base 500 is provided at the bottom of the tube body 100, a handle 600 is provided on one side of the base 500, a clamp 610 is rotatably connected to the top of the handle 600, a latch is provided at the connecting end of the clamp 610, and the latch is used to limit the opening and closing of the clamp 610. The base 500, the handle 600 and the clamp 610 are an integrated structure and can be reused, so that medical staff can hold the tube body 100 conveniently and the tube body 100 can be placed in a flat position at any time.

[0045] In this embodiment, the specific steps are as follows: Step 1, pre-place a solvent in the tube body 100 according to the application scenario, and centrifuge the solvent in the tube, place the required solvent packaged in the plastic bag 230 in the placement cavity 210 as needed, install the cutting mechanism 300 in the center of the tube cap 200, and install the tube cap 200 on the top of the tube body 100, suck the air in the tube body 100 through the needle, fix the tube body 100 on the top of the base 500, and the hoop 610 surrounds the side wall of the tube body 100, and the medical staff can hold the handle 600 to move the tube body 100;

[0046] Step 2: The blood collection object is collected through the blood collection needle. The blood collection needle is inserted into the blood collection site. The blood delivery needle is inserted into the tube body 100 through the puncture port and the rubber stopper. The blood is pumped into the vacuum tube in a jet-like manner. When the amount of blood is sufficient, the staff member pulls the blood delivery needle out of the vacuum tube and the blood collection needle out of the blood collection site.

[0047] Step 3: By confirming the patient's hematocrit (%) and blood collection volume, according to the formula C = (1.85 × 10 -3)×(100-HCT)×V to determine the amount of anticoagulant added, wherein C refers to the volume of the sodium citrate solution in mL; V refers to the amount of blood collected in mL; HCT is the hematocrit (%), the rotating sleeve (310) is rotated to drive the knife holder (320) and the knife (330) to cut through a plurality of plastic bags (230), so that the anticoagulant in the plastic bags (230) enters the tube body (100) along the drainage port (220), and the amount of anticoagulant added is determined by the position of the scale pointer (340);

[0048] Step 4: Hold the handle 600 and turn the tube 100 upside down to fully mix the blood and the solvent, perform centrifugation according to the requirements of the coagulation test, and then collect the plasma.

[0049] According to some embodiments of the present application, the initial position of the scale pointer 340 points to the 82% scale line of the scale. When the rotating sleeve 310 rotates, the position of the scale pointer 340 moves relative to the 82% scale line, making it convenient for medical staff to observe the dosage of the anticoagulant that has been added.

[0050] According to some embodiments of the present application, the device and method are suitable for conventional coagulation detection items, such as APTT, PT, FIB (fibrinogen), TT (plasma thrombin time), FDP (fibrinogen degradation product), DD (D-dimer), coagulation factor activity assay, thromboelastogram, platelet aggregation rate, lupus anticoagulant and other items.

[0051] In summary, the present invention relates to the field of medical device technology, and discloses a blood coagulation collection tube capable of adjusting the anticoagulant dosage according to HCT and a method of using the same, comprising: a tube body and a tube cap arranged on the top of the tube body; a plurality of placement cavities are arranged on the top of the tube body, the plurality of placement cavities are independent cavities, a drainage port is arranged at the bottom of the plurality of placement cavities, plastic bags are placed in the plurality of placement cavities, the plastic bags are filled with anticoagulant, a cutting mechanism is rotatably arranged on the tube cap, a scale is circumferentially arranged on the top surface of the tube cap, the cutting mechanism comprises a rotating sleeve extending into the tube cap, a knife holder arranged on the outer surface of the rotating sleeve, and a knife fixed on the knife holder, a scale pointer is arranged on the top surface of the rotating sleeve, the rotating sleeve drives the knife to rotate and cut the plastic bag, so that the anticoagulant in the plastic bag enters the tube body along the drainage port, and the device can add a corresponding amount of anticoagulant according to the patient's hematocrit, thereby improving the accuracy of the blood test results.

[0052] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and substitutions can be made without departing from the technical principles of the present invention. These improvements and substitutions should also be regarded as the scope of protection of the present invention.

Claims

1. A blood collection tube capable of adjusting the anticoagulant dosage according to HCT, comprising: A tube body (100) and a tube cap (200) arranged on the top of the tube body (100); characterized in that a plurality of placement cavities (210) are arranged on the inner side of the tube cap (200), the plurality of placement cavities (210) are independent cavities, a drainage port (220) is arranged at the bottom of the plurality of placement cavities (210), a plastic bag (230) is placed in the plurality of placement cavities (210), the plastic bag (230) is filled with an anticoagulant, a cutting mechanism (300) is arranged at the center of the tube cap (200), and a top surface of the tube cap (200) is circumferentially arranged The cutting mechanism (300) includes a rotating sleeve (310) extending into the tube cap (200), a tool holder (320) arranged on the outer surface of the rotating sleeve (310), and a tool (330) fixed on the tool holder (320). A scale pointer (340) is arranged on the top surface of the rotating sleeve (310). The rotating sleeve (310) drives the tool (330) to rotate and cut the plastic bag (230), so that the anticoagulant in the plastic bag (230) enters the tube body (100) along the drainage port (220).

2. A blood coagulation collection tube capable of adjusting the anticoagulant dosage according to HCT according to claim 1, characterized in that: The outer wall of the tube body (100) is vertically provided with scales.

3. A blood coagulation collection tube capable of adjusting the anticoagulant dosage according to HCT according to claim 1, characterized in that: The number of the placement cavities (210) is set to 27.

4. A blood coagulation collection tube capable of adjusting the anticoagulant dosage according to HCT according to claim 1, characterized in that: The capacity of the anticoagulant in the plastic bag (230) is 5.6 ul.

5. The blood coagulation collection tube according to claim 1, wherein the anticoagulant dosage can be adjusted according to HCT, 100ul of citric acid is pre-placed at the bottom of the tube body (100).

6. The blood coagulation collection tube according to claim 1, wherein the anticoagulant dosage can be adjusted according to HCT, The tube cap (200) is provided with a stirring rod (400), and the stirring rod (400) is arranged in an L shape, the horizontal portion of the stirring rod (400) extends to the outside of the tube cap (200), and the vertical portion of the stirring rod (400) extends from the top of the tube cap (200) to the inside of the tube body (100).

7. The blood coagulation collection tube according to claim 1, wherein the anticoagulant dosage can be adjusted according to HCT. A base (500) is provided at the bottom of the tube body (100), a handle (600) is provided on one side of the base (500), a clamp (610) is rotatably connected to the top of the handle (600), a latch is provided at the connection end of the clamp (610), and the latch is used to limit the opening and closing of the clamp (610).

8. The blood coagulation collection tube according to claim 1, wherein the anticoagulant dosage can be adjusted according to HCT. The initial position of the scale pointer (340) points to the 82% scale line of the scale.

9. A method for using a coagulation blood collection tube capable of adjusting the anticoagulant dosage according to HCT according to any one of claims 1 to 8, characterized in that: The specific steps of the method are as follows: Step 1: pre-place a solvent in the tube body (100) according to the application scenario, and centrifuge the solvent in the tube; place the required solvent packaged in a plastic bag (230) in the placement cavity (210) as needed; install the cutting mechanism (300) at the center of the tube cap (200), and install the tube cap (200) on the top of the tube body (100); and suck the air in the tube body (100) through a needle; Step 2: The blood collection object is collected by using a blood collection needle, the blood collection needle is inserted into the part to be collected, the blood delivery needle is inserted into the tube body (100) through the puncture port and the rubber stopper, and the blood is pumped into the vacuum tube in a jet-like manner. When the amount of blood is sufficient, the staff member pulls the blood delivery needle out of the vacuum tube and the blood collection needle out of the part to be collected; Step 3: By confirming the patient's hematocrit (%) and blood collection volume, according to the formula C = (1.85 × 10 -3 )×(100-Hct)×V to determine the amount of anticoagulant added, wherein C refers to the volume of the sodium citrate solution in mL; V refers to the amount of blood collected in mL; Hct is the hematocrit (%), the rotating sleeve (310) is rotated to drive the knife holder (320) and the knife (330) to cut through a plurality of plastic bags (230), so that the anticoagulant in the plastic bags (230) enters the tube body (100) along the drainage port (220), and the amount of anticoagulant added is determined by the position of the scale pointer (340); Step 4: Invert the tube (100) to fully mix the blood and the solvent, perform centrifugation and other treatments according to the requirements of the coagulation test, and then obtain the plasma.

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