Long-acting slow-release intestinal targeted drug delivery device for treating haemorrhoids

Abstract

The invention relates to the technical field of medical instruments, in particular to a long-acting slow-release intestinal targeted drug delivery device for treating haemorrhoids. In order to solve the problems that secondary infection is easily caused due to the fact that medicine is generally pushed to lesion and treatment parts manually in the treatment process of common internal hemorrhoids, and if disposable gloves are adopted for operation, the risk that the gloves are damaged exists, the following technical scheme is provided: the internal hemorrhoid treatment device comprises an operation cylinder, an air pump and a movable medicine feeding assembly are arranged in the operation cylinder, the medicine feeding assembly comprises a medicine feeding cylinder, a first electromagnetic valve is installed on the top wall body of the medicine feeding cylinder, and a spring is connected to the top wall body of the medicine feeding cylinder. Automatic quantitative conveying of drugs is achieved, advanced consumption caused by contact with other parts is prevented in the conveying process, meanwhile, the drug delivery structure can be detached, replaced and disinfected easily, and the purposes of repeated utilization and environmental protection are achieved.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and in particular to a long-acting sustained-release intestinal targeted drug delivery device for treating hemorrhoids. Background Art

[0002] Hemorrhoids are a common anorectal disease, mainly caused by vascular dilation and swelling in the anus and rectum, usually manifested as swelling, inflammation or bleeding. According to the location of occurrence, hemorrhoids can be divided into internal hemorrhoids and external hemorrhoids. There are many ways to treat hemorrhoids, and the more common one is a long-acting sustained-release treatment method. The long-acting sustained-release treatment of hemorrhoids is an emerging treatment method that aims to improve the symptoms and treatment effects of hemorrhoid patients by continuously releasing drugs. The long-acting sustained-release treatment of hemorrhoids is to use drugs to put them into the area that needs to be treated, so that the hemorrhoid area can achieve long-term treatment under the action of the drug. The existing internal hemorrhoids are located inside the anus and the external hemorrhoids are located outside. Compared with internal hemorrhoids, it is more convenient to treat. You only need to apply the drug to the external hemorrhoids. However, the treatment of internal hemorrhoids requires pushing the drug to the wound site, which makes the treatment more troublesome. Usually, the patient or medical staff wears disposable gloves and manually pushes the drug into the anus and pushes the drug to the internal hemorrhoids to achieve long-term sustained-release treatment of hemorrhoids.

[0003] However, in the treatment of common internal hemorrhoids, drugs are usually pushed manually to the lesions and treatment sites, which can easily lead to secondary infection. If disposable gloves are used for the operation, there is a risk of glove damage, and it is a waste of resources and not environmentally friendly. In view of this, we propose a long-acting sustained-release intestinal targeted drug delivery device for the treatment of hemorrhoids. Summary of the invention

[0004] The purpose of the present invention is to address the problems existing in the background technology and to provide a long-acting sustained-release intestinal targeted drug delivery device for treating hemorrhoids.

[0005] The technical solution of the present invention is: a long-acting sustained-release intestinal targeted drug delivery device for treating hemorrhoids, comprising an operating cylinder, an air pump and a movable drug delivery component are arranged in the operating cylinder, the drug delivery component comprises a drug delivery cylinder, a first solenoid valve is installed on the top wall of the drug delivery cylinder, a spring is connected to the top wall of the drug delivery cylinder, an internal threaded cylinder and a second solenoid valve are installed on the bottom wall of the drug delivery cylinder, and an external threaded drug delivery head is arranged at the outlet end of the second solenoid valve; A drug guiding assembly for convenient drug delivery and pressure relief is installed on the wall of the operating cylinder, and the drug guiding assembly includes a guiding box, a catheter is connected to the outlet of the guiding box, and a third solenoid valve is installed at the outlet end of the catheter; A guide assembly assisting the medicine delivery assembly in moving is sleeved on the outer wall of the operating cylinder, the guide assembly comprising a sleeve, and a limit slider is installed in a ring array on the inner ring surface of the sleeve; Auxiliary components for assisting hemorrhoid drug administration and treatment are symmetrically installed on the two side plane walls of the guide component, and the auxiliary components include a movable rod, on which a rotating shaft and a damping rod are symmetrically arranged, and both ends of the rotating shaft are connected to an auxiliary frame, and the top wall of the auxiliary frame is connected to a positioning seat, and a threaded rod is arranged on the positioning seat, and a blocking block is arranged at the bottom end of the threaded rod, and a vertical axis is connected to the top wall of the blocking block, and both ends of the damping rod are connected to contact pieces.

[0006] Preferably, a control module is arranged on the top wall of the air pump, a switch button is installed on the top wall of the control module, a first through hole is opened on the top wall of the operating cylinder, and the switch button passes through the first through hole.

[0007] Preferably, an isolation plate is installed on the inner surface wall of the operating cylinder, the air pump is installed on the top wall of the isolation plate, and the top ends of the plurality of springs are connected to the bottom wall of the isolation plate.

[0008] Preferably, the first solenoid valve is located at the opening of the top wall of the dosing barrel, and the outlet end of the first solenoid valve is connected to the inner cavity of the dosing barrel.

[0009] Preferably, the second solenoid valve is installed in the opening of the bottom wall of the dosing barrel, the inlet end of the second solenoid valve is communicated with the inner cavity of the dosing barrel, and the second solenoid valve is arranged in the internal threaded barrel.

[0010] Preferably, the inlet end of the externally threaded medicine delivery head is clamped with the outlet end of the second solenoid valve, and the inner ring surface of the internally threaded barrel is connected to a part of the outer ring surface of the externally threaded medicine delivery head by means of threads.

[0011] Preferably, a limit sliding groove is provided on the outer ring surface of the operating cylinder, and a plurality of limit sliding blocks are respectively arranged in the limit sliding grooves corresponding in position.

[0012] Preferably, a second through hole and a damping hole are provided on the rotating shaft, the position of the second through hole and the position of the damping hole are symmetrically arranged, and the rotating shaft and the damping rod are respectively arranged in the second through hole and the damping hole.

[0013] Preferably, a threaded hole and a sliding hole are provided on the positioning seat, and the bottom ends of the threaded rod and the vertical shaft pass through the threaded hole and the sliding hole respectively.

[0014] Preferably, a rotation groove is provided on the top wall of the blocking block, a bearing is arranged in the rotation groove, and the bearing sleeve is arranged on the outer ring surface of the threaded rod.

[0015] Compared with the prior art, the present invention has the following beneficial technical effects: 1. The present invention starts the air pump to pressurize the space below the isolation plate, so that the drug delivery barrel is lowered under the pressure of the air pump, and at the same time, the external threaded drug delivery head is driven to move toward the patient's treatment site, and the external threaded drug delivery head can be rotated and adjusted in height with the assistance of the internal threaded barrel, which is conducive to adjustment according to the patient's treatment site and is suitable for the treatment of internal hemorrhoids of different depths. Under the action of rotation, the external threaded drug delivery head can be disassembled, recycled, disinfected and replaced, which can be reused and is environmentally friendly. Then, by opening the first solenoid valve, it is convenient to use the guide box, the catheter and the third solenoid valve to introduce the therapeutic drug into the drug delivery barrel, and under the pressure of the air pump, the drug is discharged from the external threaded drug delivery head, so as to achieve the purpose of automatic feeding. At the same time, under the operation and control of the air pump, it is conducive to controlling the dosage according to the internal hemorrhoid situation, reducing the influence of too much or too little drug on the long-term treatment of hemorrhoids, and reducing the waste of drugs. 2. The present invention drives the sleeve down by the descending of the drug delivery cylinder, so that the sleeve and the drug delivery cylinder maintain a vertical path under the action of the limiting slider and the limiting slide groove, thereby reducing the risk of path deviation during the drug delivery process to prevent the drug delivery position from being offset and hindering subsequent treatment. At the same time, driven by the sleeve, the contact piece descends and contacts the patient's buttocks, and through the auxiliary rotation of the rotating shaft, the contact piece under pressure is used to achieve the purpose of opening the buttocks, which is beneficial to expanding the anus and reducing the discomfort caused by the external threaded drug delivery head during the insertion process, which affects the drug delivery to the hemorrhoidal area. The height of the blocking block is adjusted by twisting the threaded rod in conjunction with the bearing and the vertical axis, which is convenient for adjusting the opening angle of the movable rod, which is beneficial for different patients and convenient for the air pump to pressurize the drug in the drug delivery cylinder for drug delivery. After the feeding is completed, the device is removed, which is convenient for the contraction of the skin and flesh at the buttocks, reduces the risk of the drug escaping from the wound, and reduces the premature consumption caused by not delivering the drug to the wound. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a three-dimensional structural schematic diagram of a long-acting sustained-release intestinal targeted drug delivery device for treating hemorrhoids; Figure 2 yes Figure 1 A schematic diagram of the cross-section structure of the middle operating cylinder; Figure 3 yes Figure 1 Schematic diagram of the three-dimensional structure of the drug delivery component and the drug guide component; Figure 4 yes Figure 3 A schematic diagram of the cross-section structure of the middle medicine delivery component; Figure 5 yes Figure 1 A schematic diagram of the three-dimensional structure of the middle guide assembly; Figure 6 yes Figure 1 Schematic diagram of the expanded structure of the auxiliary components.

[0017] Figure numerals: 1. operating cylinder; 2. medicine delivery assembly; 21. medicine delivery cylinder; 22. first solenoid valve; 23. spring; 24. internally threaded cylinder; 25. second solenoid valve; 26. externally threaded medicine delivery head; 3. air pump; 4. medicine guide assembly; 41. guide box; 42. catheter; 43. third solenoid valve; 5. guide assembly; 51. sleeve; 52. limit slider; 6. auxiliary assembly; 61. movable rod; 62. rotating shaft; 63. damping rod; 64. auxiliary frame; 65. positioning seat; 66. threaded rod; 67. vertical axis; 68. blocking block; 69. contact piece; 7. control module; 8. switch button; 9. isolation plate. DETAILED DESCRIPTION

[0018] The technical solution of the present invention is further described below in conjunction with the accompanying drawings and specific embodiments.

[0019] Embodiment 1 like Figures 1 to 4 As shown, a long-acting sustained-release intestinal targeted drug delivery device for treating hemorrhoids proposed by the present invention includes an operating cylinder 1, an isolation plate 9 fixedly mounted on the inner surface wall of the operating cylinder 1, and used to isolate the space above the isolation plate 9 from the space below, an air pump 3 is located in the upper space inside the operating cylinder 1, and is fixedly mounted on the top wall of the isolation plate 9, the air pump 3 is supported by the isolation plate 9, and the output end of the air pump 3 passes through the opening in the middle part of the isolation plate 9, which is beneficial to pressurizing the space below the isolation plate 9 and facilitating subsequent drug delivery; a control module 7 is fixedly mounted at the top of the inner wall of the operating cylinder 1, and is mounted on the top wall of the air pump 3, a switch button 8 is mounted on the control module 7, and passes through the first through hole opened on the top wall of the operating cylinder 1, which is beneficial to cooperate with the control module 7 to operate the switch of the air pump 3.

[0020] Furthermore, a movable medicine delivery component 2 is provided in the operating cylinder 1, and the medicine delivery component 2 includes a medicine delivery cylinder 21, a first solenoid valve 22, a spring 23, an internally threaded cylinder 24, a second solenoid valve 25 and an externally threaded medicine delivery head 26. The medicine delivery cylinder 21 is located below the isolation plate 9, and the bottom ends of the plurality of springs 23 are fixedly connected to the top wall of the medicine delivery cylinder 21, and the top ends are fixedly connected to the bottom wall of the isolation plate 9, which is beneficial for lowering the medicine delivery cylinder 21 under the pressure of the air pump 3, and with the assistance of the spring 23, it is convenient to reset the medicine delivery cylinder 21 after the pressure is released; the first solenoid valve 22 is fixedly installed at the opening of the top wall of the medicine delivery cylinder 21, and the outlet end of the first solenoid valve 22 is connected to the inner cavity of the medicine delivery cylinder 21, which is beneficial for guiding the medicine into the inner cavity of the medicine delivery cylinder 21, and at the same time, it is convenient to use the pressure output by the air pump 3 to squeeze and discharge the medicine in the medicine delivery cylinder 21; The internal threaded barrel 24 is fixedly mounted on the bottom wall of the dosing barrel 21, and the second solenoid valve 25 is located in the internal threaded barrel 24. At the same time, the top of the second solenoid valve 25 is also fixedly connected to the bottom wall of the dosing barrel 21, and the inlet end of the second solenoid valve 25 is arranged in the opening at the bottom wall of the dosing barrel 21, which is conducive to guiding the discharge of the medicine in the dosing barrel 21; the external threaded drug delivery head 26 is arranged in the internal threaded barrel 24, and the inlet end of the external threaded drug delivery head 26 is clamped with the outlet end of the second solenoid valve 25. The two are in a sealed state in the clamped state, which is conducive to allowing the drug to pass through the second solenoid valve 25 from the external threaded drug delivery head to the outlet end. The medicine is discharged from the medicine head 26 to avoid direct contact between the second solenoid valve 25 and the patient, which makes it difficult to clean and disinfect. Part of the structure of the external threaded medicine delivery head 26 is in a threaded connection state with the internal threaded barrel 24. The inner circle depth of the outlet end of the second solenoid valve 25 is greater than the inlet end depth of the external threaded medicine delivery head 26, which is conducive to rotating the external threaded medicine delivery head 26 to adjust the drug delivery depth, facilitating subsequent accurate drug delivery, and in the rotating state of the external threaded medicine delivery head 26, the user can disassemble and replace it, which is conducive to disinfection and cleaning, and is convenient for subsequent secondary use, achieving the purpose of reuse and environmental protection; Furthermore, a drug guiding assembly 4 for convenient drug delivery and pressure relief is installed on the wall of the operating cylinder 1, and the drug guiding assembly 4 includes a guide box 41, a catheter 42 and a third solenoid valve 43. The guide box 41 is fixedly mounted on the outer surface wall of the operating cylinder 1, and the catheter 42 is arranged in the operating cylinder 1. The inlet end of the catheter 42 passes through the opening on the outer wall of the operating cylinder 1 and is connected to the outlet of the guide box 41, which is conducive to guiding the drug into the catheter 42 through the opening at the top of the guide box 41. The third solenoid valve 43 is fixedly mounted on the outlet end of the catheter 42 and is in a clamping state with the first solenoid valve 22 in a non-working state, which is conducive to introducing the drug into the inner cavity of the dosing cylinder 21, facilitating the subsequent drug administration to the hemorrhoids, and during the resetting process of the dosing cylinder 21, the third solenoid valve 43 can be opened to cooperate with the first solenoid valve 22 in the open state to exhaust and reduce the pressure in the operating cylinder 1, which is conducive to the next use.

[0021] Embodiment 2 like Figures 1 to 5As shown, a long-acting sustained-release intestinal targeted drug delivery device for treating hemorrhoids proposed by the present invention, compared with the first embodiment, this embodiment also includes an operating cylinder 1, a drug delivery component 2, an air pump 3, a drug guide component 4, a control module 7, a switch button 8 and an isolation plate 9. A guide component 5 for assisting the drug delivery component 2 in moving is sleeved on the outer wall of the operating cylinder 1, and the guide component 5 includes a sleeve 51 and a limiting slider 52. The sleeve 51 is sleeved on the outer ring of the bottom end of the operating cylinder 1 and the drug delivery cylinder 21, and the opening of the bottom wall of the sleeve 51 is fixedly connected to the outer ring surface at the bottom end of the drug delivery cylinder 21, which is conducive to driving the sleeve 51 to move under the action of the activity of the drug delivery cylinder 21; a plurality of limiting sliders 52 are welded on the inner ring surface of the sleeve 51 in a ring array state, and are arranged in a plurality of limiting slide grooves opened on the outer ring surface of the operating cylinder 1, which is conducive to cooperating with the sleeve 51 to guide the drug delivery cylinder 21 in the active state, so that the drug delivery cylinder 21 keeps vertical lifting and lowering, and its trajectory is offset during movement, affecting the accuracy of the subsequent drug delivery position.

[0022] Further, auxiliary components 6 for assisting hemorrhoid drug administration treatment are symmetrically installed on the two side plane walls of the guide component 5, and the auxiliary component 6 includes a movable rod 61, a rotating shaft 62, a damping rod 63, an auxiliary frame 64, a positioning seat 65, a threaded rod 66, a vertical shaft 67, a blocking block 68 and a contact member 69. The rotating shaft 62 and the damping rod 63 are symmetrically arranged in the second through hole and the damping hole symmetrically opened on the movable rod 61. The inner walls on both sides of the auxiliary frame 64 are fixedly connected to the two ends of the rotating shaft 62, and the top wall of the auxiliary frame 64 is fixedly connected to the bottom wall of the positioning seat 65. The side wall of the positioning seat 65 is connected to the sleeve 51. The plane wall is fixedly connected, so that the movable rod 61 can be rotated under the cooperation of the rotating shaft 62 and the second rotating hole, which is convenient for opening and closing the movable rod 61; the inner walls on both sides of the contact member 69 are fixedly connected to the two ends of the damping rod 63, and the contact member 69 can be closely attached to the patient's buttocks. Due to the liftable setting of the sleeve 51, the contact member 69 can use the gradually opened movable rod 61 to apply pressure to the buttocks, so that the patient's anus can be gradually opened, reducing the resistance during the insertion of the external threaded drug delivery head 26, reducing the risk of poking the patient's internal hemorrhoids, and providing convenience for subsequent drug delivery work; The threaded rod 66 passes through the threaded hole provided on the positioning seat 65, and a bearing is sleeved on the outer ring surface at the bottom end thereof. The bearing is arranged on the blocking block 68 located below the positioning seat 65, and is arranged in a rotation groove provided on the top wall of the blocking block 68, so that the blocking block 68 can be adjusted in the process of rotating the threaded rod 66, which is conducive to adjusting the blocking position of the movable rod 61 under the height adjustment of the blocking block 68, so as to be suitable for the drug administration of internal hemorrhoids of different depths, and under the effect of blocking, it is conducive to preventing the movable rod 61 from continuously opening, causing discomfort to the patient during the drug administration process, and affecting the drug administration work; the bottom end of the vertical shaft 67 passes through the sliding hole provided on the positioning seat 65, and is fixedly connected to the top wall of the blocking block 68, which is conducive to preventing the blocking block 68 from rotating with the threaded rod 66, avoiding affecting the height adjustment of the blocking block 68, and at the same time, after the drug administration is completed, when the movable rod 61 is released from the open state, the skin and flesh can be tightened to reduce the risk of drug leakage, and in the process of opening the drug administration, it is conducive to avoiding the premature effect caused by the contact of the drug with the non-lesion part.

[0023] The above-mentioned specific embodiments are only several preferred embodiments of the present invention. Based on the technical solutions of the present invention and the relevant inspirations of the above-mentioned embodiments, those skilled in the art can make various alternative improvements and combinations to the above-mentioned specific embodiments.

Claims

1. A long-acting sustained-release intestinal targeted drug delivery device for treating hemorrhoids, comprising an operating cylinder (1), Features: An air pump (3) and a movable medicine delivery component (2) are arranged in the operating cylinder (1), and the medicine delivery component (2) comprises a medicine delivery cylinder (21), a first electromagnetic valve (22) is installed on the top wall of the medicine delivery cylinder (21), a spring (23) is connected to the top wall of the medicine delivery cylinder (21), an internal thread cylinder (24) and a second electromagnetic valve (25) are installed on the bottom wall of the medicine delivery cylinder (21), and an externally threaded medicine delivery head (26) is arranged at the outlet end of the second electromagnetic valve (25); A drug guiding assembly (4) for convenient drug delivery and pressure relief is installed on the wall of the operating cylinder (1), the drug guiding assembly (4) comprising a guiding box (41), the outlet of the guiding box (41) is connected to a conduit (42), and the outlet end of the conduit (42) is installed with a third solenoid valve (43); A guide assembly (5) for assisting the movement of the medicine delivery assembly (2) is sleeved on the outer wall of the operating cylinder (1), the guide assembly (5) comprising a sleeve (51), and a limit slider (52) is mounted in a ring array on the inner ring surface of the sleeve (51); Auxiliary components (6) for assisting drug administration and treatment of hemorrhoids are symmetrically mounted on the two side plane walls of the guide component (5). The auxiliary component (6) comprises a movable rod (61). A rotating shaft (62) and a damping rod (63) are symmetrically arranged on the movable rod (61). The two ends of the rotating shaft (62) are connected to an auxiliary frame (64). The top wall of the auxiliary frame (64) is connected to a positioning seat (65). The positioning seat (65) is provided with a threaded rod (66). A blocking block (68) is arranged at the bottom end of the threaded rod (66). The top wall of the blocking block (68) is connected to a vertical shaft (67). The two ends of the damping rod (63) are connected to contact pieces (69).

2. A long-acting sustained-release intestinal targeted drug delivery device for treating hemorrhoids according to claim 1, It is characterized in that A control module (7) is arranged on the top wall of the air pump (3), a switch button (8) is installed on the top wall of the control module (7), a first through hole is opened on the top wall of the operating cylinder (1), and the switch button (8) passes through the first through hole.

3. The intestinal targeted drug delivery device for treating hemorrhoids with long-acting sustained-release according to claim 1, It is characterized in that An isolation plate (9) is installed on the inner surface wall of the operating cylinder (1), the air pump (3) is installed on the top wall of the isolation plate (9), and the top ends of the plurality of springs (23) are connected to the bottom wall of the isolation plate (9).

4. The intestinal targeted drug delivery device for treating hemorrhoids with long-acting sustained-release according to claim 1, It is characterized in that The first solenoid valve (22) is located at an opening of the top wall of the medication barrel (21), and an outlet end of the first solenoid valve (22) is in communication with the inner cavity of the medication barrel (21).

5. The intestinal targeted drug delivery device for treating hemorrhoids with long-acting sustained-release according to claim 1, It is characterized in that The second solenoid valve (25) is installed in an opening of the bottom wall of the dosing barrel (21), the inlet end of the second solenoid valve (25) is connected to the inner cavity of the dosing barrel (21), and the second solenoid valve (25) is arranged in the internal threaded barrel (24).

6. A long-acting sustained-release intestinal targeted drug delivery device for treating hemorrhoids according to claim 1, It is characterized in that The inlet end of the externally threaded medicine delivery head (26) is clamped with the outlet end of the second electromagnetic valve (25), and the inner ring surface of the internally threaded barrel (24) is connected to a part of the outer ring surface of the externally threaded medicine delivery head (26) by means of threads.

7. The intestinal targeted drug delivery device for treating hemorrhoids with long-acting sustained-release according to claim 1, It is characterized in that A limit sliding groove is provided on the outer ring surface of the operating cylinder (1), and a plurality of limit sliding blocks (52) are respectively arranged in the limit sliding grooves corresponding in position.

8. The intestinal targeted drug delivery device for treating hemorrhoids with long-acting sustained-release according to claim 1, It is characterized in that The rotating shaft (62) is provided with a second through hole and a damping hole, the position of the second through hole and the position of the damping hole are symmetrically arranged, and the rotating shaft (62) and the damping rod (63) are arranged in the second through hole and the damping hole respectively.

9. The intestinal targeted drug delivery device for treating hemorrhoids with long-acting sustained-release according to claim 1, It is characterized in that The positioning seat (65) is provided with a threaded hole and a sliding hole, and the bottom ends of the threaded rod (66) and the vertical shaft (67) respectively penetrate the threaded hole and the sliding hole.

10. The intestinal targeted drug delivery device for treating hemorrhoids with long-acting sustained release according to claim 1, It is characterized in that A rotation groove is provided on the top wall of the blocking block (68), a bearing is arranged in the rotation groove, and the bearing is sleeved on the outer ring surface of the threaded rod (66).

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