An embedding device for preparing nano lipid carrier
By designing the embedding equipment for nanolipid carrier preparation, the rotation and lifting mechanism are used to ensure that the spherical nanoliposome embedded lutein ester products are uniformly heated, solving the problems of uneven heating and low detection efficiency in the prior art, and improving the The accuracy of the test results is achieved.
Patent Information
- Application Number
- CN202411661233.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-20
- Publication Date
- 2025-02-07
- Estimated Expiration
- 2044-11-20
AI Technical Summary
The prior art detects spherical nanoliposome embedded lutein ester products, which is uneven in heat, which affects the detection results, and requires frequent replacement of the placement seat, which consumes time and reduces the detection efficiency.
An embedded device for preparing nanolipid carriers is designed, including a temperature control box, a rotating mechanism, a lifting mechanism and a gripping mechanism. The gripping mechanism clamps the product and rotates it in the air. The lifting mechanism adjusts the product position to ensure uniform heat absorption. .
By reducing the contact area between the product and the heat source, the risk of lutein esters degradation due to high temperature is reduced, uniform heating is achieved, the accuracy of the detection results is improved, and the detection efficiency of products of different diameters is improved.
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Figure CN119147344B_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the field of detection technology, in particular to an embedding device for preparing a nano lipid carrier. Background Art
[0002] The high-phospholipid krill oil, a new type of phospholipid functional molecule derived from Antarctic krill, uses liposome technology to encapsulate lutein esters. It is an active, fresh-keeping small molecule liquid functional product that combines the advantages of both krill oil and lutein esters. Liposome technology is a technology that encapsulates active ingredients in liposomes similar to cell structures, which can improve the stability and bioavailability of active ingredients. Through this technology, high-phospholipid krill oil and lutein esters can be effectively combined to form a stable complex that is easily absorbed by the human body. After the complex is formed, it is necessary to simulate specific temperature and environmental conditions to determine the stability of the lutein ester-encapsulated product.
[0003] At present, in the prior art, when measuring spherical nanoliposome-encapsulated lutein ester products, they are generally placed directly on a placement seat adapted for spherical nanoliposome-encapsulated lutein ester products. Therefore, when the product is heated, the upper side of the product close to the heating plate has too much heat, while the side away from the heating plate has less heat, and the part covered by the placement seat cannot be heated, which will cause uneven heating of the product, thereby affecting the test results;
[0004] In addition, when placing spherical nanoliposome-encapsulated lutein ester products of different diameters, the placement seat needs to be replaced frequently. The replacement of the placement seat requires the use of tools to install it one by one, which takes a lot of time, thus affecting the detection effect and also resulting in low practicality of the placement seat. Summary of the invention
[0005] The purpose of the present invention is to solve the shortcomings of the background technology and to propose an embedding device for preparing a nano-lipid carrier.
[0006] To achieve the above purpose, the technical solution adopted by the present invention is: an embedding device for preparing a nano-lipid carrier, comprising a temperature control box, the inner wall of which is fixedly connected to a heating plate, the temperature control box is respectively provided with a rotating mechanism and a lifting mechanism, the rotating mechanism is provided with a grabbing mechanism, the lifting mechanism is provided with a moving adjustment mechanism, and the bottom end of the temperature control box is provided with a collecting mechanism;
[0007] The grabbing mechanism comprises a rotating plate, four sides of the outer wall of the rotating plate are provided with square notches, the inner walls of the four square notches are fixedly connected with fixed shafts, the outer walls of the four fixed shafts are rotatably connected with grabbing plates for clamping the spherical nanoliposome-embedded lutein ester product, the four grabbing plates are composed of two straight plates with an included angle of 150 degrees, the outer sides of the two ends of the four grabbing plates corresponding to the fixed shafts are provided with grooves, and the four groups of the grooves and the fixed shafts are fixedly connected with coil springs for reset movement;
[0008] The movable adjustment mechanism includes a lifting block, a movable plate slidingly penetrates the lifting block, a circular hole is penetrated on the top of the movable plate, the inner wall of the circular hole is rotatably connected with a rotating shaft and penetrates the movable plate, a rolling ball is fixedly connected to the inner side of the outer wall of the rotating shaft corresponding to the circular hole, the rolling ball contacts the spherical nanoliposome-embedded lutein ester product and rotates it, and a second motor is fixedly connected to the end of the movable plate away from the temperature control box, and the driving end of the second motor is fixedly connected to the rotating shaft.
[0009] Preferably, the rotating mechanism includes a fixed column that rotates and passes through the top of the temperature control box, the outer wall of the fixed column is fixedly connected to an external gear ring, and also includes a rotating motor fixedly connected to a side of the fixed column corresponding to the top of the temperature control box, the driving end of the rotating motor is fixedly connected to a driving shaft, the top of the driving shaft is fixedly connected to a gear, and the gear is meshingly connected to the external gear ring.
[0010] Preferably, the grabbing mechanism also includes a circular column fixedly connected to the top of the rotating plate, the circular column and the fixed column are fixedly connected, a lifting chamber is arranged inside the circular column, four sides of the inner wall of the lifting chamber are penetrated with through holes, a lifting plate is arranged at the bottom of the inner wall of the lifting chamber, four sides of the outer side of the lifting plate are fixedly connected with second fixed plates passing through the through holes, and four second fixed plates are in contact with four grabbing plates respectively.
[0011] Preferably, the grabbing mechanism also includes a circular groove opened at the top of the fixed column, a circular plate is fixedly connected to the inner wall of the circular groove, a hydraulic rod is fixedly connected to the bottom end of the circular plate, and the telescopic end of the hydraulic rod is fixedly connected to the lifting plate and passes through the fixed column and the circular column.
[0012] Preferably, the movable adjustment mechanism also includes a first fixed plate fixedly connected to one end of the lifting block, a sliding groove is provided on the top of the first fixed plate, a sliding block is slidably connected to the inner wall of the sliding groove, and the sliding block is fixedly connected to the movable plate.
[0013] Preferably, one end of the slide is rotatably connected to a threaded rod, the threaded rod and the slider are threadedly connected, the end of the first fixed plate away from the temperature control box is fixedly connected to the first motor, the driving end of the first motor is fixedly connected to the threaded rod, and when the slider contacts the other side of the slide, the rolling ball reaches directly below the spherical nanoliposome-embedded lutein ester product.
[0014] Preferably, the movable adjustment mechanism also includes a square hole passing through one end of the temperature control box, the lifting block and the square hole are slidably connected, telescopic grooves are provided at both upper and lower ends of the square hole, telescopic plates are provided on the inner walls of the two telescopic grooves, and the two telescopic plates are fixedly connected to the lifting block.
[0015] Preferably, a first fixed block is fixedly connected above the square hole corresponding to one end of the temperature control box, an electric push rod is fixedly connected to the bottom end of the first fixed block, a second fixed block is fixedly connected to the telescopic end of the electric push rod, and the second fixed block is fixedly connected to the lifting block.
[0016] Preferably, the collecting mechanism comprises an inclined plate fixedly connected to the inner wall of the temperature control box, two inclined plates are provided and arranged in a staggered manner, and a feed discharge port is provided at the bottom end of the temperature control box.
[0017] Preferably, the collection mechanism also includes a collection box fixedly connected to the bottom end of the temperature control box, a collection frame is provided on the inner wall of the collection box, a flip motor is fixedly connected to one end of the collection box and the temperature control box, a rotating shaft is fixedly connected to the driving end of the flip motor, the other end of the rotating shaft is rotatably connected to the collection box, and a baffle is fixedly connected to the outer wall of the rotating shaft and is provided below the discharge port.
[0018] Compared with the prior art, the present invention has the following beneficial effects:
[0019] 1. Through the setting of the grabbing mechanism, the spherical nanoliposome-embedded lutein ester product can be clamped and placed on the arc-shaped notch on the grabbing plate, so that the spherical nanoliposome-embedded lutein ester product can be suspended, thereby reducing the contact area with the heat source, reducing the risk of lutein ester degradation due to high temperature, and can be heated evenly, improving the detection results, and can grab spherical nanoliposome-embedded lutein ester products of different diameters, thereby improving the detection efficiency;
[0020] 2. Through the setting of the rotating mechanism, the grabbing mechanism can be rotated, so that the suspended spherical nanoliposome-embedded lutein ester product can be in a state of uniform rotation on the horizontal plane, which can further ensure uniform heating everywhere and further improve the detection effect;
[0021] 3. Through the setting of the lifting mechanism, it can be adjusted according to the spherical nanoliposomes encapsulating lutein ester products of different diameters, so that the rolling ball can contact the spherical nanoliposomes encapsulating lutein ester products of different diameters, which is convenient for subsequent operations;
[0022] 4. By setting the mobile adjustment mechanism, the spherical nanoliposome-embedded lutein ester product can be rotated on the vertical plane, so that the position of the spherical nanoliposome-embedded lutein ester product can be adjusted, thereby making the product more evenly heated and improving the accuracy of detection;
[0023] 5. By setting up the collection mechanism, the evenly heated spherical nanoliposome-embedded lutein ester product can be collected, which is convenient for subsequent detection operations. BRIEF DESCRIPTION OF THE DRAWINGS
[0024] Figure 1 It is an overall schematic diagram of an embedding device prepared by a nano-lipid carrier of the present invention;
[0025] Figure 2 A schematic diagram of another perspective of an embedding device prepared by a nano-lipid carrier of the present invention;
[0026] Figure 3 The embedding device prepared by a nano lipid carrier of the present invention Figure 2 Enlarged view of point A in the middle;
[0027] Figure 4 This is a diagram of the internal structure of a temperature control box of an embedding device for preparing a nano-lipid carrier of the present invention;
[0028] Figure 5 A cross-sectional view of a fixed column and a circular column of an embedding device prepared for a nano-lipid carrier of the present invention;
[0029] Figure 6 A cross-sectional view of a rotating plate of an embedding device for preparing a nano-lipid carrier of the present invention;
[0030] Figure 7 The embedding device prepared by a nano lipid carrier of the present invention Figure 6 Enlarged view of point B in the middle;
[0031] Figure 8 A cross-sectional view of a temperature control box for an embedding device for preparing a nano-lipid carrier of the present invention;
[0032] Fig. 9 A cross-sectional view of a moving plate of an embedding device prepared for a nano-lipid carrier of the present invention;
[0033] Fig.10 A cross-sectional view of a collection box of an embedding device for preparing a nano-lipid carrier of the present invention.
[0034] In the figure: 1, temperature control box; 2, fixed column; 3, outer gear ring; 4, circular groove; 5, gear; 6, rotating motor; 7, electric push rod; 8, moving plate; 9, collection box; 10, collection frame; 11, flip motor; 12, driving shaft; 13, first fixed block; 14, second fixed block; 15, lifting block; 16, square hole; 17, telescopic plate; 18, first fixed plate; 19, first motor; 20, second motor; 21, rotating plate; 22 , circular column; 23, rolling ball; 24, inclined plate; 25, feeding port; 26, lifting chamber; 27, through hole; 28, second fixed plate; 29, square notch; 30, grab plate; 31, hydraulic rod; 32, circular plate; 33, groove; 34, fixed shaft; 35, coil spring; 36, heating plate; 37, telescopic slot; 38, circular hole; 39, rotating shaft; 40, slide groove; 41, threaded rod; 42, slider; 43, rotating shaft; 44, baffle. DETAILED DESCRIPTION
[0035] The following description is used to disclose the present invention so that those skilled in the art can implement the present invention. The preferred embodiments described below are only examples, and those skilled in the art may think of other obvious variations.
[0036] like Figure 1-Figure 10 The embedding device for preparing a nano-lipid carrier shown in the figure comprises a temperature control box 1, the inner wall of which is fixedly connected with a heating plate 36, through which the spherical nano-liposome-embedded lutein ester product is heated, and a rotating mechanism and a lifting mechanism are respectively provided on the temperature control box 1, the rotating mechanism is provided with a grabbing mechanism, and the lifting mechanism is provided with a moving adjustment mechanism, and a collecting mechanism is provided at the bottom of the temperature control box 1, and the spherical nano-liposome-embedded lutein ester product can be grabbed and clamped by the grabbing mechanism to be in a suspended state, and the setting of the rotating mechanism can rotate the spherical nano-liposome-embedded lutein ester product to make it evenly heated, and the lifting mechanism can lift up and down with the moving adjustment mechanism, and the moving adjustment mechanism is used to perform vertical rotation adjustment on the spherical nano-liposome-embedded lutein ester product;
[0037] like Figure 4-Figure 7 As shown, the grabbing mechanism includes a rotating plate 21, and square notches 29 are formed on four sides of the outer wall of the rotating plate 21, and the inner walls of the four square notches 29 are fixedly connected to fixed shafts 34, and the outer walls of the four fixed shafts 34 are rotatably connected to grabbing plates 30 for clamping the spherical nanoliposome-embedded lutein ester product, and the four grabbing plates 30 are composed of two straight plates with an included angle of 150 degrees, and grooves 33 are formed on the outer sides of the fixed shafts 34 at both ends of the four grabbing plates 30, and the four groups of grooves 33 and the fixed shafts 34 are fixedly connected with coil springs 35 for reset movement;
[0038] like Figure 2-Figure 3 , Figure 8-Figure 9 As shown, the movable adjustment mechanism includes a lifting block 15, and a movable plate 8 is slidably penetrated on the lifting block 15. A circular hole 38 is penetrated on the top of the movable plate 8. The inner wall of the circular hole 38 is rotatably connected to a rotating shaft 39 and penetrates the movable plate 8. The outer wall of the rotating shaft 39 is fixedly connected to the inner side of the circular hole 38. The rolling ball 23 contacts the spherical nanoliposome-embedded lutein ester product and rotates it. The end of the movable plate 8 away from the temperature control box 1 is fixedly connected to the second motor 20, and the driving end of the second motor 20 is fixedly connected to the rotating shaft 39.
[0039] like Figure 1 , Figure 2 , Figure 4 As shown, the rotating mechanism includes a fixed column 2 that rotates and runs through the top of the temperature control box 1, and the outer wall of the fixed column 2 is fixedly connected to an outer gear ring 3, and also includes a rotating motor 6 that is fixedly connected to the top of the temperature control box 1 and corresponds to one side of the fixed column 2. The driving end of the rotating motor 6 is fixedly connected to a driving shaft 12, and the top of the driving shaft 12 is fixedly connected to a gear 5, and the gear 5 is meshed with the outer gear ring 3. The rotating motor 6 drives the driving shaft 12 to rotate, thereby driving the gear 5 to rotate. Since the gear 5 is meshed with the outer gear ring 3, the fixed column 2 can be rotated, and the spherical nanoliposome-embedded lutein ester product can be rotated, so that it is evenly heated to ensure the test results.
[0040] like Figure 5 , Figure 6 As shown, the grabbing mechanism also includes a circular column 22 fixedly connected to the top of the rotating plate 21, the circular column 22 is fixedly connected to the fixed column 2, a lifting chamber 26 is arranged inside the circular column 22, through holes 27 are penetrated on the four sides of the inner wall of the lifting chamber 26, a lifting plate is arranged at the bottom of the inner wall of the lifting chamber 26, second fixing plates 28 are fixedly connected to the four sides of the outer side of the lifting plate and pass through the through holes 27, and the four second fixing plates 28 are in contact with the four grabbing plates 30 respectively. The lifting plate moves up and down in the lifting chamber 26 and limits the lifting plate, and at the same time, the second fixing plate 28 is in contact with the through holes 27, so that the second fixing plate 28 can be limited.
[0041] like Figure 5 As shown, the grabbing mechanism also includes a circular groove 4 opened at the top of the fixed column 2, a circular plate 32 is fixedly connected to the inner wall of the circular groove 4, a hydraulic rod 31 is fixedly connected to the bottom end of the circular plate 32, and the telescopic end of the hydraulic rod 31 is fixedly connected to the lifting plate and penetrates the fixed column 2 and the circular column 22. The hydraulic rod 31 is placed through the circular groove 4, and the hydraulic rod 31 is fixed and limited by the circular plate 32. Since the hydraulic rod 31 is set outside, the cables on the hydraulic rod 31 will not be damaged during the heating process.
[0042] like Figure 3 , Fig. 9As shown, the movable adjustment mechanism also includes a first fixed plate 18 fixedly connected to one end of the lifting block 15, a slide groove 40 is provided at the top of the first fixed plate 18, a slider 42 is slidably connected to the inner wall of the slide groove 40, and the slider 42 is fixedly connected to the movable plate 8. The slider 42 moves in the slide groove 40, thereby moving the movable plate 8 to perform the adjustment operation, and the slide groove 40 limits the slider 42, and the positioning operation is performed when the slider 42 contacts the other side of the slide groove 40.
[0043] like Figure 3 , Fig. 9 As shown, one end of the chute 40 is rotatably connected to a threaded rod 41, the threaded rod 41 and the slider 42 are threadedly connected, the end of the first fixed plate 18 away from the temperature control box 1 is fixedly connected to the first motor 19, the driving end of the first motor 19 is fixedly connected to the threaded rod 41, and when the slider 42 contacts the other side of the chute 40, the rolling ball 23 reaches directly below the spherical nanoliposome-embedded lutein ester product. The slider 42 can be moved by the thread effect of the threaded rod 41, and the first motor 19 provides power and rotates the threaded rod 41.
[0044] like Figure 3 , Figure 8 As shown, the mobile adjustment mechanism also includes a square hole 16 penetrated at one end of the temperature control box 1, the lifting block 15 and the square hole 16 are slidably connected, and telescopic grooves 37 are provided at both ends of the square hole 16. Telescopic plates 17 are provided on the inner walls of the two telescopic grooves 37, and the two telescopic plates 17 are fixedly connected to the lifting block 15. The lifting block 15 is limited by the square hole 16, and the telescopic plates 17 on the upper and lower sides slide in the telescopic grooves 37 on the upper and lower sides respectively, and are closed.
[0045] like Figure 3 As shown, a first fixing block 13 is fixedly connected above one end of the temperature control box 1 corresponding to the square hole 16, an electric push rod 7 is fixedly connected to the bottom end of the first fixing block 13, a second fixing block 14 is fixedly connected to the telescopic end of the electric push rod 7, and the second fixing block 14 is fixedly connected to the lifting block 15. The electric push rod 7 is limited by the first fixing block 13, and is connected to the lifting block 15 by the second fixing block 14, so as to facilitate subsequent operation and processing.
[0046] like Figure 4 As shown, the collecting mechanism includes an inclined plate 24 fixedly connected to the inner wall of the temperature control box 1, and the number of inclined plates 24 is set to two and staggered, and a feeding port 25 is opened at the bottom of the temperature control box 1. The inclined plate 24 is inclined, and the two sides are fixedly connected with limit rods, which can prevent the spherical nanoliposome-embedded lutein ester product from deviating to the sides and sliding down until it falls into the feeding port 25.
[0047] like Figure 1-Figure 2 , Figure 4 , Fig.10As shown, the collection mechanism also includes a collection box 9 fixedly connected to the bottom end of the temperature control box 1, a collection frame 10 is arranged on the inner wall of the collection box 9, a flip motor 11 is fixedly connected to one end of the collection box 9 and the temperature control box 1, a rotating shaft 43 is fixedly connected to the driving end of the flip motor 11, the other end of the rotating shaft 43 is rotatably connected to the collection box 9, and a baffle 44 is fixedly connected to the outer wall of the rotating shaft 43 and arranged below the discharge port 25. The collection frame 10 is entered through the discharge port 25, and the collection frame 10 can be drawn out, so as to facilitate the taking and testing of the sample, and the baffle 44 is rotated by the rotation of the rotating shaft 43 driven by the flip motor 11, so as to open the discharge port 25 when needed and block the discharge port 25 when not needed.
[0048] Working principle: first, the spherical nanoliposome-embedded lutein ester product is placed under the rotating plate 21, and then the hydraulic rod 31 is started to move the lifting plate upward, and the second fixed plate 28 is moved upward. Since the second fixed plate 28 is in contact with the grab plate 30, when the second fixed plate 28 moves upward, the upper half of the grab plate 30 will gradually tend to a vertical state, and the lower half will gradually tend to a horizontal state, so that the spherical nanoliposome-embedded lutein ester products of different diameters can be clamped, and when clamping, a certain distance is left between the spherical nanoliposome-embedded lutein ester product and the rotating plate 21, so that the spherical nanoliposome-embedded lutein ester product can have a certain activity space, and then the rotating motor 6 is started to rotate the driving shaft 12, the driving shaft 12 rotates the gear 5, the gear 5 rotates the outer gear ring 3 and the fixed column 2, and the fixed column 2 rotates the circular column 22, so that the spherical nanoliposome-embedded lutein ester product can rotate at a uniform speed, so that the spherical nanoliposome-embedded lutein ester product is evenly heated, thereby improving the detection effect;
[0049] Further, the first motor 19 is started to rotate the threaded rod 41, and the slider 42 can be moved by the thread effect of the threaded rod 41, thereby moving the movable plate 8, and when the slider 42 contacts the other side of the slide groove 40, the ball 23 just reaches the bottom of the spherical nanoliposome-embedded lutein ester product, and then the electric push rod 7 is started to move the second fixed block 14, thereby moving the lifting block 15, and the telescopic plates 17 on the upper and lower sides move in the telescopic groove 37 and play a sealing role to prevent the heat in the temperature control box 1 from escaping, and the lifting block 15 moves with the movable plate 8, so that the ball 23 can contact the spherical nanoliposome-embedded lutein ester product, and then the second motor 20 is started to rotate the rotating shaft 39, and the rotating shaft 39 rotates with the ball 23, so that it can rotate on the vertical plane to complete the adjustment, further improve the uniform heating effect, and improve the accuracy of detection;
[0050] Furthermore, after the temperature is measured, the flip motor 11 is started to rotate the rotating shaft 43, thereby rotating the baffle 44 to open the feed opening 25, and then the hydraulic rod 31 is started to move the lifting plate downward, thereby moving the second fixed plate 28 downward. At this time, the elastic reset action of the coil spring 35 can make the grab plate 30 perform a reset movement, thereby releasing the spherical nanoliposome-embedded lutein ester product and dropping it on the inclined plate 24. Since the inclined plate 24 is inclined, the spherical nanoliposome-embedded lutein ester product will gradually slide down and enter the collection frame 10 through the feed opening 25 to complete the collection operation.
[0051] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited to the above embodiments. The above embodiments and descriptions only describe the principles of the present invention. The present invention may be subject to various changes and improvements without departing from the spirit and scope of the present invention. These changes and improvements fall within the scope of the present invention. The scope of protection claimed by the present invention is defined by the attached claims and their equivalents.
Claims
1. An embedding device for preparing a nano-lipid carrier, comprising a temperature control box (1), wherein a heating plate (36) is fixedly connected to the inner wall of the temperature control box (1), characterized in that: The temperature control box (1) is provided with a rotating mechanism and a lifting mechanism, the rotating mechanism is provided with a grabbing mechanism, the lifting mechanism is provided with a moving adjustment mechanism, and the bottom end of the temperature control box (1) is provided with a collecting mechanism; The grabbing mechanism comprises a rotating plate (21), the outer wall of the rotating plate (21) is provided with square notches (29) on four sides, the inner walls of the four square notches (29) are fixedly connected to fixed shafts (34), the outer walls of the four fixed shafts (34) are rotatably connected to grabbing plates (30) for clamping the spherical nanoliposome-embedded lutein ester product, the four grabbing plates (30) are composed of two straight plates with an included angle of 150 degrees, the outer sides of the two ends of the four grabbing plates (30) corresponding to the fixed shafts (34) are provided with grooves (33), and the four groups of grooves (33) and the fixed shafts (34) are fixedly connected with coil springs (35) for reset movement; The movable adjustment mechanism comprises a lifting block (15), a movable plate (8) slidably penetrated on the lifting block (15), a circular hole (38) is penetrated at the top of the movable plate (8), a rotating shaft (39) is rotatably connected to the inner wall of the circular hole (38) and penetrates the movable plate (8), a rolling ball (23) is fixedly connected to the inner side of the outer wall of the rotating shaft (39) corresponding to the circular hole (38), the rolling ball (23) contacts the spherical nanoliposome-embedded lutein ester product and causes it to rotate, and a second motor (20) is fixedly connected to one end of the movable plate (8) away from the temperature control box (1), and a driving end of the second motor (20) is fixedly connected to the rotating shaft (39).
2. The embedding device for preparing a nano-lipid carrier according to claim 1, characterized in that: The rotating mechanism comprises a fixed column (2) which rotates and passes through the top of the temperature control box (1), the outer wall of the fixed column (2) being fixedly connected to an outer gear ring (3), and also comprises a rotating motor (6) which is fixedly connected to a side of the top of the temperature control box (1) corresponding to the fixed column (2), the driving end of the rotating motor (6) being fixedly connected to a driving shaft (12), the top of the driving shaft (12) being fixedly connected to a gear (5), and the gear (5) and the outer gear ring (3) are meshingly connected.
3. The embedding device for preparing a nano-lipid carrier according to claim 2, characterized in that: The gripping mechanism further comprises a circular column (22) fixedly connected to the top of the rotating plate (21), the circular column (22) being fixedly connected to the fixed column (2), a lifting chamber (26) being arranged inside the circular column (22), through holes (27) being penetrated on four sides of the inner wall of the lifting chamber (26), a lifting plate being arranged at the bottom of the inner wall of the lifting chamber (26), second fixing plates (28) being fixedly connected to four sides of the outer side of the lifting plate and passing through the through holes (27), and four second fixing plates (28) being in contact with four gripping plates (30) respectively.
4. The embedding device for preparing a nano-lipid carrier according to claim 3, characterized in that: The grabbing mechanism further comprises a circular groove (4) formed at the top end of the fixed column (2); a circular plate (32) is fixedly connected to the inner wall of the circular groove (4); a hydraulic rod (31) is fixedly connected to the bottom end of the circular plate (32); a telescopic end of the hydraulic rod (31) is fixedly connected to the lifting plate and penetrates the fixed column (2) and the circular column (22).
5. The embedding device for preparing a nano-lipid carrier according to claim 1, characterized in that: The movable adjustment mechanism further comprises a first fixed plate (18) fixedly connected to one end of the lifting block (15); a sliding groove (40) is provided at the top of the first fixed plate (18); a sliding block (42) is slidably connected to the inner wall of the sliding groove (40); and the sliding block (42) is fixedly connected to the movable plate (8).
6. The embedding device for preparing a nano-lipid carrier according to claim 5, characterized in that: One end of the slide groove (40) is rotatably connected to a threaded rod (41), the threaded rod (41) and the slider (42) are threadedly connected, the end of the first fixed plate (18) away from the temperature control box (1) is fixedly connected to a first motor (19), the driving end of the first motor (19) is fixedly connected to the threaded rod (41), and when the slider (42) contacts the other side of the slide groove (40), the rolling ball (23) reaches directly below the spherical nanoliposome-encapsulated lutein ester product.
7. The embedding device for preparing a nano-lipid carrier according to claim 6, characterized in that: The movable adjustment mechanism further comprises a square hole (16) penetrating one end of the temperature control box (1); the lifting block (15) and the square hole (16) are slidably connected; the square hole (16) is provided with telescopic grooves (37) at both upper and lower ends; the inner walls of the two telescopic grooves (37) are provided with telescopic plates (17); and the two telescopic plates (17) are fixedly connected to the lifting block (15).
8. The embedding device for preparing a nano-lipid carrier according to claim 7, characterized in that: A first fixed block (13) is fixedly connected above one end of the temperature control box (1) corresponding to the square hole (16); an electric push rod (7) is fixedly connected to the bottom end of the first fixed block (13); a second fixed block (14) is fixedly connected to the telescopic end of the electric push rod (7); and the second fixed block (14) is fixedly connected to the lifting block (15).
9. The embedding device for preparing a nano-lipid carrier according to claim 1, characterized in that: The collecting mechanism comprises an inclined plate (24) fixedly connected to the inner wall of the temperature control box (1), two inclined plates (24) are provided and arranged in a staggered manner, and a material discharge port (25) is provided at the bottom end of the temperature control box (1).
10. The embedding device for preparing a nano-lipid carrier according to claim 9, characterized in that: The collecting mechanism further comprises a collecting box (9) fixedly connected to the bottom end of the temperature control box (1), a collecting frame (10) being arranged on the inner wall of the collecting box (9), a turning motor (11) being fixedly connected to one end of the collecting box (9) and the temperature control box (1), a rotating shaft (43) being fixedly connected to the driving end of the turning motor (11), the other end of the rotating shaft (43) being rotatably connected to the collecting box (9), and a baffle (44) being fixedly connected to the outer wall of the rotating shaft (43) and being arranged below the discharge port (25).
Citation Information
Patent Citations
Temperature adjusting type mouse pad
CN110275629A
Accurate-positioning quality detection device for food safety
CN112834709A