Traditional Chinese medicine preparation for treating chronic heart failure

Abstract

The invention relates to the technical field of Chinese herbal medicines, and particularly discloses a traditional Chinese medicine preparation for treating chronic heart failure, which is prepared from the following raw materials by weight: 12-18g of radix aconiti carmichaeli, 12-18g of poria cocos, 12-18g of semen plantaginis, 12-18g of polyporus umbellatus, 12-18g of ligusticum wallichii, 25-30g of astragalus membranaceus, 10-15g of codonopsis pilosula, 8-10g of cassia twig, 10-15g of glossy privet fruit, 25-35g of semen lepidii, 10-15 of peach kernel and 15-20g of radix pseudostellariae. According to the invention, a standardized chronic heart failure treatment scheme taking a diuretic and ACE I medicines as footstones is utilized, and meanwhile, a Chinese herbal medicine formula is added to assist a patient in rapid rehabilitation, so that side effects caused by long-term taking of western medicines are effectively avoided, and normal heart rate of the patient is guaranteed.

Description

Technical Field

[0001] The invention belongs to the technical field of Chinese herbal medicines, and particularly relates to a Chinese medicine preparation for treating chronic heart failure. Background Art

[0002] Heart failure is a complex clinical syndrome caused by various heart diseases progressing to a serious stage. Its main features are left ventricular and (or) right ventricular dysfunction and changes in neurohumoral regulation, often accompanied by dyspnea, fluid retention, reduced exercise tolerance and significantly shortened survival time. Patients with underlying heart disease are more likely to develop heart failure. This disease cannot be cured, and the goal of treatment is to prevent and delay the occurrence and development of heart failure, relieve clinical symptoms, improve quality of life, improve long-term prognosis, and reduce mortality and hospitalization rates.

[0003] Although Western medicine has proposed a standardized chronic heart failure treatment plan based on evidence-based medicine, with diuretics and ACEI drugs as the cornerstone, the survival rate of heart failure is still low, and the 5-year survival rate is close to that of malignant tumors. Patients' physical activities are significantly limited. Some patients cannot adhere to long-term Western medicine treatment due to the side effects of Western medicine. During the treatment, the side effects on the human body are relatively large, and the human heart rate cannot be guaranteed. Summary of the invention

[0004] The purpose of the present invention is to provide a Chinese medicine preparation for treating chronic heart failure to solve the problems raised in the above background technology.

[0005] To achieve the above object, the present invention provides the following technical solutions:

[0006] A traditional Chinese medicine preparation for treating chronic heart failure comprises the following raw materials by weight: 12-18g of aconite root, 12-18g of poria, 12-18g of plantain seed, 12-18g of umbellatus, 12-18g of ligusticum chuanxiong, 25-30g of astragalus, 10-15g of codonopsis pilosula, 8-10g of cassia twig, 10-15g of glossy privet fruit, 25-35g of scutellaria baicalensis seed, 10-15g of peach kernel and 15-20g of pseudostellaria.

[0007] Preferably, the Chinese medicine preparation includes the following weight amounts: 15g of Aconite, 15g of Poria, 15g of Plantago, 15g of Polyporus, 15g of Ligusticum chuanxiong, 30g of Astragalus, 15g of Codonopsis, 9g of Cinnamon Twig, 15g of Ligustrum lucidum, 30g of Lemongrass, 15g of Persica and 15g of Pseudostellaria.

[0008] Preferably, the Chinese medicine preparation includes the following weight amounts: 18g of Aconite, 18g of Poria, 18g of Plantago, 18g of Polyporus, 18g of Ligusticum chuanxiong, 30g of Astragalus, 15g of Codonopsis, 10g of Cinnamon Twig, 15g of Ligustrum lucidum, 35g of Lemongrass, 15g of Persica, and 20g of Pseudostellaria.

[0009] Among them, Poria cocos is a kind of Chinese herbal medicine of fungus, and its main active ingredients are Poria cocos polysaccharide, Poria cocos acid, ergosterol, choline, histidine, adenine, lecithin, etc. Poria cocos polysaccharide has the ability to regulate immunity, can activate T lymphocytes and B lymphocytes, and can resist various bacterial and viral infections; Poria cocos polysaccharide can also resist thymus atrophy and enhance the phagocytic ability of macrophages, which enhances immunity from another aspect. In addition, Poria cocos also has the effect of delaying aging and can inhibit the occurrence and development of tumors.

[0010] Among them, aconite is a traditional Chinese medicine, the main active ingredients are alkaloids such as aconitine and methenamine, as well as lipids, organic acids and trace elements. Aconite has the effects of strengthening the heart, resisting arrhythmia, resisting myocardial ischemia and hypoxia, resisting shock, enhancing immune function, anti-inflammatory, analgesic, anticoagulant, anti-thrombotic, and inhibiting the central nervous system.

[0011] Among them, the effective components of Chinese medicine of Plantago are mucus, succinic acid, plantaginol, adenine, choline, plantaginine, fatty oil, vitamin A and B vitamins, etc. Plantago can promote the secretion of respiratory mucus, dilute sputum, and have expectorant, antitussive and antiasthmatic effects; it has an inhibitory effect on various bacilli and staphylococci; it can increase the excretion of water, sodium chloride, urea and uric acid and has a diuretic effect; it can lower cholesterol; in modern clinical practice, it can be used to treat congestive heart failure, upper gastrointestinal bleeding, acute icteric hepatitis, etc.

[0012] Among them, Poria is a medicinal fungus, and its effective ingredients include Polyporus polysaccharide, ergosterol, crude protein, polypeptides and various trace elements. Polyporus polysaccharide can improve the phagocytic ability of phagocytes in the human body, inhibit the activity of viruses, and accelerate the regeneration of immune cells. Ergosterol can enhance the body's immune function, crude protein and polypeptides can play an anti-aging role, and trace elements can regulate the internal environment of the human body.

[0013] Among them, Chuanxiong is a traditional Chinese medicine, and its main active ingredients are volatile oils, alkaloids, lactones, phenols and organic acids, etc. Modern pharmacological studies have shown that Chuanxiong can inhibit vascular smooth muscle contraction, dilate coronary arteries, increase coronary blood flow, reduce peripheral vascular resistance, improve microcirculation, inhibit platelet aggregation, resist thrombosis, and promote bone marrow hematopoiesis, sedation, spasm relief, immune function regulation, anti-radiation and anti-tumor effects.

[0014] Astragalus, the effective ingredients of traditional Chinese medicine are saponins, flavonoids, polysaccharides, various amino acids, iron, manganese, zinc and other trace elements. The trace element selenium contained in Astragalus can fight against carcinogenic heavy metals such as cadmium and mercury, and is an element necessary for the human body to resist tumors. Astragalus polysaccharides and flavonoids contained in Astragalus can enhance the activity of the body's antioxidant SOD, promote lipid metabolism, and lower blood lipids. Astragalosides, astragalus polysaccharides, and flavonoids in Astragalus have the effect of scavenging free radicals, which can inhibit lipid peroxidation damage, scavenge oxygen free radicals, reduce the damage of oxygen free radicals to the cardiovascular system, and improve cardiac microcirculation.

[0015] Codonopsis, the effective ingredients of Codonopsis are codonoside, glucose, inulin, polysaccharide, codonopsis alkaloids, volatile oils, etc. Codonopsis has the effects of tonifying the middle and replenishing qi, strengthening the spleen and lungs, anti-cancer, improving intelligence and calming the mind. It is mainly used to treat symptoms such as weak spleen and stomach, insufficient qi and blood, poor appetite and loose stools, palpitations and shortness of breath. At the same time, Codonopsis can also enhance the body's immunity, promote hematopoiesis, and anti-aging.

[0016] Cinnamon twig, the effective ingredients of traditional Chinese medicine of cinnamon twig are cinnamaldehyde, cinnamonic acid, volatile oil, etc. Cinnamon twig has the effects of sweating and relieving muscles, warming the meridians and unblocking blood vessels, and assisting yang and transforming qi. Its chemical components mainly contain volatile oils such as cinnamaldehyde and cinnamonic acid, as well as phenols, glycosides, organic acids, polysaccharides, coumarins and other ingredients. Cinnamon oil can dilate blood vessels, improve blood circulation, and promote blood flow to the body surface, which is conducive to sweating and relieving fever. Cinnamaldehyde has antipyretic and cooling effects; decoctions and alcohol extracts have inhibitory effects on Staphylococcus aureus, Salmonella typhi, skin fungi, and influenza viruses. Cinnamon oil and cinnamaldehyde have inhibitory effects on Mycobacterium tuberculosis. Cinnamon oil has the effects of invigorating the stomach, relieving gastrointestinal spasms, diuresis, and strengthening the heart. Cinnamaldehyde has analgesic, sedative, anticonvulsant, and anti-tumor effects

[0017] Ligustrum lucidum fruit, the effective ingredients of traditional Chinese medicine are glucose, palmitic acid, stearic acid, oleic acid, linolenic acid, copper, zinc, iron, manganese and other trace elements, as well as pentacyclic triterpenoid compounds oleanolic acid, ursolic acid and phenylethanoid glycoside component salidroside. Ligustrum lucidum fruit tastes sweet and bitter, and is cool in nature. It enters the liver and kidney meridians and has the effects of enhancing immunity, increasing peripheral leukocytes, enhancing the phagocytic ability of the reticuloendothelial system, and enhancing cellular and humoral immunity. It can be mainly used to treat symptoms such as blurred vision, internal heat due to yin deficiency, dizziness, premature graying of hair and beard, insomnia, dreaminess, sore waist and knees, hot flashes and irritability caused by liver and kidney yin deficiency

[0018] Tinglizi is a traditional Chinese medicine, which is the seeds of the plants of the genus Tingli, the genus Lepidium and the genus Artemisia. It tastes pungent and bitter, is cold in nature, and enters the lung, bladder and large intestine meridians. It has the effects of purging the lung and lowering qi, removing phlegm and relieving asthma, promoting diuresis and reducing swelling, and purging heat and expelling evil. It is mainly used to treat asthma, cough and sputum caused by phlegm blocking the lungs, lung abscess, edema, pleural effusion, dysuria, chronic cor pulmonale, asthma and swelling caused by heart failure, and also treats carbuncle, malignant sore, scrofula and tuberculosis.

[0019] Peach kernel, the effective ingredients of traditional Chinese medicine are amygdalin, volatile oil, fatty oil, amygdalin, protease, etc. Peach kernel has the effects of promoting blood circulation and removing blood stasis, moistening the intestines and relieving constipation, relieving cough and relieving asthma. Its chemical components mainly contain amygdalin, volatile oil, fatty oil, amygdalin, protease, etc., which have anti-inflammatory, analgesic, anti-tumor, anti-fatigue and other effects.

[0020] Pseudostellariae Radix, the effective ingredients of traditional Chinese medicine are saponins, sugars, cyclopeptide B, etc. Pseudostellariae Radix has the effects of invigorating qi and strengthening the spleen, promoting body fluid and moistening the lungs. Its chemical components mainly include saponins, sugars, cyclopeptide B, etc. These ingredients have certain effects in enhancing immunity, anti-fatigue and anti-aging.

[0021] Compared with the prior art, the present invention has the following beneficial effects:

[0022] The present invention not only utilizes a standardized chronic heart failure treatment program based on diuretics and ACEI drugs, but also adds a Chinese herbal medicine formula to assist the patient in rapid recovery, effectively avoid the side effects of long-term use of Western medicine, and ensure the patient's normal heart rate. DETAILED DESCRIPTION

[0023] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0024] Embodiment 1:

[0025] A traditional Chinese medicine preparation for treating chronic heart failure, comprising the following raw materials by weight: 15g of aconite root, 15g of poria, 15g of plantain seed, 15g of umbellatus, 15g of ligusticum chuanxiong, 30g of astragalus, 15g of codonopsis pilosula, 9g of cassia twig, 15g of glossy privet fruit, 30g of scutellaria baicalensis seed, 15g of peach kernel and 15g of pseudostellaria.

[0026] How to use this recipe:

[0027] Every patient admitted to the hospital is informed of the management of their lifestyle and diet, and is given conventional Western medicine treatment according to their respective conditions, including cardiotonic drugs (digitalis), diuretics (furosemide), vasodilators (nitroglycerin), and drugs such as beta-blockers, angiotensin-converting enzyme inhibitors (ACEI) or angiotensin Il receptor blockers (ARB). Patients with other complications such as hypertension and coronary heart disease are given symptomatic antihypertensive and lipid-lowering treatments.

[0028] The patients in the treatment group need to take the formula of the present invention in addition to conventional western medicine treatment, and the medication period is more than half a year.

[0029] The user prepares the required Chinese medicinal materials: ensure the required weight of Aconite, Poria, Plantago, Polyporus, Ligusticum chuanxiong, Astragalus, Codonopsis, Cassia twig, Ligustrum lucidum, Lepidium, Prunus persica and Pseudostellaria baicalensis are weighed, and ensure their quality and purity.

[0030] Wash the Chinese medicinal materials: Soak the Chinese medicinal materials in clean water for a period of time, then wash them clean to remove mud and other impurities. Dry the Chinese medicinal materials: Dry the washed Chinese medicinal materials to ensure that there is no moisture on the surface.

[0031] Slicing or crushing: Slice or crush the Chinese medicinal materials as needed. When the user needs to use them, the user puts the prepared quality medicinal materials into the casserole.

[0032] Before decocting the medicine, soak it in clean water for 30-40 minutes. After soaking, pour the medicine into the casserole for the first decoction. The amount of water added should be about 3 cm above the surface of the medicine. The amount of water for the second decoction should be reduced as appropriate. For tonic Chinese medicine, more water should be added as appropriate. The first decoction should be boiled for 20 minutes; the second decoction should be boiled for 15 minutes.

[0033] Use high heat when the Chinese medicine is not boiling, and use low heat after boiling. Stir frequently during the cooking process.

[0034] Generally, each dose of Chinese medicine needs to be decocted twice, each time until the amount of medicine is about 150 ml. Mix the two decoctions together for a total of 300 ml, divide it into two portions, and take it once in the morning and once in the evening.

[0035] The flavor and dosage of the medicine can be increased or decreased according to the specific symptoms of the patient. For example, when the patient has sleep problems such as restless nights, the heart-nourishing and calming drugs such as Ziziphus jujuba seeds, Polygala tenuifolia, and Polygala tenuifolia can be added as appropriate; if the patient has obvious cough and asthma, the cough and asthma-relieving drugs such as Fritillaria thunbergii and Gecko can be added as appropriate; if the patient has severe chest tightness and pain, the pungent and aromatic drugs such as Agarwood and Sandalwood can be added.

[0036] Embodiment 2:

[0037] A traditional Chinese medicine preparation for treating chronic heart failure comprises the following raw materials by weight: 18g of aconite root, 18g of poria, 18g of plantain seed, 18g of umbellatus, 18g of ligusticum chuanxiong, 30g of astragalus, 15g of codonopsis pilosula, 10g of cassia twig, 15g of glossy privet fruit, 35g of scutellaria baicalensis seed, 15g of peach kernel and 20g of pseudostellaria.

[0038] The method of using this formulation is the same as the method of using described in embodiment 1.

[0039] It is worth noting that the flavor and dosage of the medicine can be increased or decreased according to the specific symptoms of the patient. For example, when the patient has sleep problems such as restless nights, the heart-nourishing and calming drugs such as Ziziphus jujuba seeds, Polygala tenuifolia, and Polygala tenuifolia can be added as appropriate; if the patient has obvious cough and asthma, the cough and asthma-relieving drugs such as Fritillaria thunbergii and Gecko can be added as appropriate; if the patient has severe chest tightness and pain, the spicy and aromatic drugs such as Agarwood and Sandalwood can be added.

[0040] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A Chinese medicine preparation for treating chronic heart failure, characterized in that: The invention comprises the following raw materials by weight: 12-18g of aconite root, 12-18g of poria, 12-18g of plantain seed, 12-18g of umbellate, 12-18g of ligusticum chuanxiong, 25-30g of astragalus, 10-15g of codonopsis pilosula, 8-10g of cassia twig, 10-15g of glossy privet fruit, 25-35g of scutellaria baicalensis seed, 10-15g of peach kernel and 15-20g of pseudostellaria.

2. A Chinese medicine preparation for treating chronic heart failure according to claim 1, characterized in that: The Chinese medicine preparation includes the following raw materials by weight: 15g of aconite root, 15g of poria, 15g of plantain seed, 15g of umbellate, 15g of ligusticum chuanxiong, 30g of astragalus, 15g of codonopsis pilosula, 9g of cassia twig, 15g of glossy privet fruit, 30g of scutellaria baicalensis seed, 15g of peach kernel and 15g of pseudostellaria.

3. A Chinese medicine preparation for treating chronic heart failure according to claim 1, characterized in that: The Chinese medicine preparation includes the following raw materials by weight: 18g of aconite root, 18g of poria, 18g of plantain seed, 18g of umbellatus, 18g of ligusticum chuanxiong, 30g of astragalus, 15g of codonopsis pilosula, 10g of cassia twig, 15g of glossy privet fruit, 35g of scutellaria baicalensis seed, 15g of peach kernel and 20g of pseudostellaria.