Rhinitis cream formula, preparation method and application

By using rhinitis ointment prepared with specific Chinese medicine ingredients, the side effects and unstable efficacy problems in existing rhinitis treatment methods are solved, and the rapid, safe and suitable rhinitis treatment effect is achieved, reducing costs and avoiding systemic side effects.

CN119185439APending Publication Date: 2024-12-27BINZHOU ENZHI INFORMATION TECHNOLOGY CO LTD
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Patent Information

Application Number
CN202411302570.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-09-18
Publication Date
2024-12-27

AI Technical Summary

Technical Problem

The existing rhinitis treatment methods have side effects and unstable efficacy. Drug treatment may cause side effects such as drowsiness and dry mouth. Surgical treatment is traumatic and expensive, and physical treatment effect is unstable and costly. Traditional Chinese medicine rhinitis ointment can be used as a topical drug. Avoid systemic side effects but the formulation and preparation methods have not been systematically optimized.

Method used

Use fried Chinese medicine ingredients such as Cangzi kernel, Cangzi, Schizonepeta, Fenwind, Angelica dahurica, Cangzi, Acorus granulis, Asarum, Scutellaria baicalensis, Gentiana, Mint ice and dimethyl sulfoxide to prepare them through specific preparation methods Rhinitis ointment that has the effects of relieving wind and cold, promoting lungs and promoting orifices and eliminating wind and heat, avoiding systemic side effects and is suitable for long-term use.

Benefits of technology

It has achieved rapid relief of rhinitis symptoms, good safety and compliance, suitable for long-term use, significantly improved the treatment effect of rhinitis, reduced the risk of side effects, and was low in cost. It is suitable for a variety of rhinitis types.

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Abstract

The invention relates to the field of traditional Chinese medicine preparations, in particular to an ointment formula for treating rhinitis and a preparation method thereof. The ointment is prepared from the following raw materials: honeysuckle extract, peppermint oil, vaseline, borneol, glycerol and the like, and the components have a synergistic effect, so that the rhinitis symptom can be effectively relieved. The preparation method comprises the steps of raw material mixing, heating and dissolving, cooling and filling and the like, and is simple in process and easy to implement. Experiments prove that the ointment has a remarkable curative effect on rhinitis patients, and is small in side effect and high in safety. The invention provides a new effective scheme for rhinitis treatment, and has a wide market application prospect.
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Description

Technical Field

[0001] The invention relates to the field of traditional Chinese medicine preparations, in particular to a rhinitis ointment formula for treating rhinitis and a preparation method thereof. Background Art

[0002] Rhinitis is a common chronic inflammatory disease, mainly including allergic rhinitis, chronic rhinitis and acute rhinitis. The main symptoms of rhinitis include nasal congestion, runny nose, sneezing, nasal itching and hyposmia, which seriously affect the patient's quality of life and work efficiency. At present, the incidence of rhinitis is increasing year by year, especially in modern society with air pollution and lifestyle changes, rhinitis has become a global health problem. Modern medicine mainly treats rhinitis with medication, surgery and physical therapy. In terms of medication, there are drugs used to relieve the symptoms of allergic rhinitis, such as loratadine and cetirizine. This type of drug has a significant effect, but long-term use may cause side effects such as drowsiness and dry mouth, and has limited effect on some patients. Fluticasone propionate, mometasone furoate, etc. can effectively relieve the symptoms of rhinitis, but long-term use may cause side effects such as nasal dryness and bleeding, and some patients are dependent on hormone drugs. Although surgical treatment is effective, it is only applicable to rhinitis caused by organic lesions such as turbinate hypertrophy and nasal septum deviation. Surgery is traumatic, has a long recovery period, and may cause postoperative complications, affecting the patient's normal life. Physical therapy includes laser therapy, low-temperature plasma ablation and other technologies, which have certain curative effects, but the cost is high, and the treatment effect varies from person to person, so it is difficult to guarantee long-term efficacy.

[0003] Traditional Chinese medicine has a long history and rich experience in treating rhinitis, emphasizing overall conditioning and treating both the symptoms and the root causes. As a kind of TCM external medicine, rhinitis ointment can directly exert its efficacy by applying it to the nasal mucosa. It has the following advantages: rhinitis ointment is directly applied to the nasal mucosa, and the medicine can quickly penetrate into the affected area, exerting anti-inflammatory, anti-allergic and orifice-opening effects; rhinitis ointment is an external medicine, which avoids the systemic side effects that may be caused by oral drugs, such as drowsiness, gastrointestinal discomfort, etc.; rhinitis ointment is easy to use and easy for patients to accept, especially suitable for children and elderly patients; rhinitis ointment usually uses a variety of Chinese medicine compatibility, which can take into account the effects of clearing heat and detoxification, dispersing wind and cold, promoting blood circulation and removing blood stasis, etc., and fundamentally improve the condition of rhinitis.

[0004] Based on the above background, the present invention provides a traditional Chinese medicine rhinitis ointment, which is prepared into an ointment by selecting Chinese medicinal materials and reasonably compatibility, and has a significant effect of treating rhinitis. The rhinitis ointment can quickly relieve rhinitis symptoms, has good safety and compliance, and is suitable for long-term use. Summary of the invention

[0005] The invention provides a rhinitis ointment formula and a preparation method thereof. The rhinitis ointment is composed of Chinese medicinal ingredients such as stir-fried cangzi seeds, xanthium sibiricum seeds (outer skin), schizonepeta, siler, angelica dahurica, magnolia, calamus, xanthium sibiricum seeds, asarum, scutellaria baicalensis, gentian, mint ice, dimethyl sulfoxide and the like. The rhinitis ointment with the effects of dispelling wind and cold, promoting lung function and clearing the orifices, and removing wind and heat is prepared by a specific preparation method.

[0006] The specific ingredients and their proportions are as follows: 9 grams of stir-fried cangzi kernel, 100 grams of xanthium sibiricum, 30 grams of schizonepeta, 20 grams of saposhnikovia divaricata, 20 grams of angelica dahurica, 20 grams of magnolia, 15 grams of calamus, 18 grams of asarum, 12 grams of scutellaria baicalensis, 15 grams of gentian, 35 grams of peppermint ice, 30 grams of dimethyl sulfoxide, 200 grams of sesame oil, and 1000 grams of medical cream.

[0007] The preparation method is as follows: stir-fry the Xanthium sibiricum among the above-mentioned Chinese medicinal ingredients until it turns yellow-brown and then deep-fry it in sesame oil until it is dry. Grind it into fine powder with Xanthium sibiricum seeds, Schizonepeta tenuifolia, Saposhnikovia divaricata, Angelica dahurica, Magnolia officinalis, Acorus calamus, Asarum, Scutellaria baicalensis and Gentiana scabra respectively, mix them together with mint ice melted with alcohol, dimethyl sulfoxide and medical cream, stir evenly and make it into an ointment to obtain the rhinitis ointment.

[0008] The rhinitis ointment of the invention has a unique formula, a simple preparation method, low cost, significant therapeutic effect, and no obvious side effects, and can be widely used in the treatment of rhinitis. DETAILED DESCRIPTION

[0009] Step 1: Place the clean Xanthium sibiricum fruits in a frying container and heat over medium heat. When the surface becomes yellow-brown and the thorns are burnt, remove from the frying pan, let cool, grind to remove the thorns, and sieve.

[0010] Step 2: peel some of the Xanthium sibiricum obtained in step 1 and take out its kernel for later use. The purpose is to increase the proportion of Xanthium sibiricum kernel in the ingredients, which is also the key to the treatment of rhinitis in this formula.

[0011] Step 3: Deep-fry some of the Xanthium sibiricum obtained in step 1 in sesame oil according to the proportion, remove them and keep the sesame oil.

[0012] Step 4: Grind the seeds of Xanthium sibiricum, Nepeta tenuifolia, Saposhnikovia divaricata, Angelica dahurica, Magnolia officinalis, Acorus calamus, Asarum, Scutellaria baicalensis and Gentiana scabra into fine powder respectively, mix them evenly through a 100-mesh sieve to obtain medicinal powder.

[0013] Step 5: Use appropriate amount of alcohol to melt the mint ice.

[0014] Step 6: Pour the medical cream into a container, mix the powder obtained in step 4, the mint ice and dimethyl sulfoxide melted in step 5, and the sesame oil of fried Xanthium sibiricum in step 3 in the container containing the medical cream, and stir evenly until a paste is formed.

[0015] Step 7: Put the ointment obtained in step 6 into a sterilized container and seal it for storage to obtain the rhinitis ointment. Usage and steps

[0016] The first step is to clean the nasal cavity: use clean water to wash away the secretions in the nasal cavity to keep the nasal cavity clean.

[0017] The second step is to apply ointment: Use a cotton swab to dip an appropriate amount of rhinitis ointment and apply it inside the nasal cavity, especially in areas where symptoms such as nasal congestion, itchy nose, sneezing and runny nose are obvious.

[0018] Step 3: Gently massage: After applying the ointment, gently massage the affected area to promote the absorption and effectiveness of the medicine.

[0019] Dosage and Administration: Use twice a day, in the morning after getting up and at night after washing up for better results.

Claims

1. A rhinitis ointment formula, characterized in that: It is composed of the following Chinese medicinal ingredients: stir-fried cangzi kernel, xanthium fruit, schizonepeta, angelica dahurica, magnolia, calamus, xanthium fruit, asarum, scutellaria baicalensis, gentian, mint ice, dimethyl sulfoxide and other Chinese medicinal ingredients.

2. The rhinitis ointment formula according to claim 1, characterized in that The proportions of each Chinese medicinal ingredient are: 9 grams of stir-fried cangzi kernel, 100 grams of xanthium sibiricum, 30 grams of schizonepeta, 20 grams of saposhnikovia divaricata, 20 grams of angelica dahurica, 20 grams of magnolia, 15 grams of calamus, 18 grams of asarum, 12 grams of scutellaria baicalensis, 15 grams of gentian, 35 grams of peppermint ice, 30 grams of dimethyl sulfoxide, 200 grams of sesame oil, and 1000 grams of medical cream.

3. A method for preparing the rhinitis ointment according to claim 1 or 2, characterized in that: The following steps are involved: Step 1: Put the clean Xanthium sibiricum into a frying container, heat over medium heat, fry until the surface is yellow-brown and the thorns are burnt, take it out, let it cool, grind to remove the thorns, and sieve it; Step 2: peel some of the Xanthium sibiricum obtained in step 1 and take out its kernel for later use. The purpose is to increase the proportion of Xanthium sibiricum kernel in the ingredients, which is also the key to the treatment of rhinitis in this formula; Step 3: deep-fry some of the Xanthium sibiricum obtained in step 1 in sesame oil according to a certain proportion until dry, remove the dried Xanthium sibiricum and retain the sesame oil; Step 4: Grind the seeds of Xanthium sibiricum, Nepeta tenuifolia, Angelica dahurica, Magnolia officinalis, Acorus calamus, Asarum, Scutellaria baicalensis, and Gentiana scabra into fine powder respectively, and mix them evenly through a 100-mesh sieve to obtain medicinal powder; Step 5: Use appropriate amount of alcohol to melt the mint ice; Step 6: introducing the medical cream into a container, mixing the powder obtained in step 4, the mint ice and dimethyl sulfoxide melted in step 5, and the sesame oil of fried Xanthium sibiricum in step 3 into the container containing the medical cream and stirring evenly until a paste is formed; Step 7: Put the ointment obtained in step 6 into a sterilized container and seal it for storage to obtain the rhinitis ointment.

4. Usage method and steps: Step 1: Clean the nasal cavity. Use clean water to wash away the secretions in the nasal cavity to keep the nasal cavity clean; Step 2: Apply ointment. Use a cotton swab to apply an appropriate amount of rhinitis ointment to the inside of the nasal cavity, especially to areas with obvious symptoms such as nasal congestion, itching, sneezing and runny nose; Step 3: Gently massage. After applying the ointment, gently massage the affected area to promote the absorption and effect of the medicine.

5. Usage and dosage: For best results, use twice a day, in the morning after waking up and at night after washing up.

Citation Information

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