A reagent kit design method and system for preventing external contamination interference

Abstract

The present invention discloses a kit design method and system for preventing external pollution interference, which relates to the field of reagent detection technology, including: calculating the viscosity coefficient of the kit candidate material and the test pollution source; generating at least one kit candidate material combination; calculating the comprehensive pollution residual coefficient of the kit candidate material combination; selecting the kit candidate material combination with the smallest comprehensive pollution residual coefficient as the target kit candidate material combination; generating the actual production material of the kit; obtaining the kit shape architecture; establishing a hole sealing leakage model; obtaining the air inlet and air outlet design parameters; designing a blocking block that blocks the air inlet and air outlet. By setting a coefficient calculation module, a data calculation module, a model building module and a hole design module, it can be ensured that the test of the kit is not interfered by the pollution source to a large extent during the test, thereby ensuring the accuracy of the test result, so that the test has a high degree of credibility.

Description

Technical Field

[0001] The present invention relates to the technical field of reagent detection, and in particular to a method and system for designing a reagent kit for preventing external pollution interference. Background Art

[0002] A test kit is a box used to hold chemical reagents for testing chemical components, drug residues, virus types, etc. It is generally used in hospitals and pharmaceutical companies. With the development of the medical and chemical industries, some convenient test kits have become rapidly popular.

[0003] The test kit will be affected by pollution sources in the environment, resulting in reduced test accuracy. Existing test kits are relatively lacking in design to prevent interference from external pollution, and their current structure cannot properly reduce interference from external pollution. Summary of the invention

[0004] In order to solve the above-mentioned technical problems, a method and system for designing a test kit that can prevent interference from external pollution are provided. The technical solution solves the problem that the test of the test kit proposed in the above-mentioned background technology will be affected by the pollution sources in the environment, resulting in a decrease in test accuracy. The existing test kit is relatively lacking in the design of preventing interference from external pollution, and its current structure cannot properly reduce the interference from external pollution.

[0005] In order to achieve the above purpose, the technical solution adopted by the present invention is:

[0006] A method for designing a test kit to prevent external contamination interference, comprising:

[0007] Obtain at least one reagent type to be tested using the test kit, and based on the big data, obtain at least one test contamination source that affects the test result of the reagent type;

[0008] Based on the big data, at least one candidate material of the test kit is obtained, and the viscosity coefficient between the candidate material of the test kit and the test contamination source is calculated;

[0009] generating at least one candidate material combination for a test kit, wherein the candidate material combination for a test kit is composed of at least one candidate material for a test kit and a usage ratio of the candidate material for the test kit;

[0010] Based on the viscosity coefficient, the comprehensive contamination residual coefficient of the candidate material combination of the kit is calculated;

[0011] Select the candidate material combination of the test kit with the smallest comprehensive contamination residual coefficient as the candidate material combination of the target test kit;

[0012] Using at least one candidate material of the target kit candidate material combination, heating and mixing according to the usage ratio of the candidate materials of the kit to generate actual production materials of the kit;

[0013] Based on the test capacity of the test kit, the appearance structure of the test kit is designed to obtain the appearance architecture of the test kit;

[0014] Establish a hole sealing leakage model;

[0015] Based on the test kit appearance structure and the hole sealing leakage model, the number, position and aperture of the air inlet and air outlet of the test kit are designed to obtain the design parameters of the air inlet and air outlet, where the aperture is the diameter;

[0016] Based on the design parameters of the air inlet and the air outlet, a blocking block for blocking the air inlet and the air outlet is designed.

[0017] Preferably, the step of obtaining at least one test contamination source that affects the test results of the reagent type based on big data comprises the following steps:

[0018] Acquire at least one pollutant in the ambient air whose average density is greater than a preset ratio;

[0019] Taking a preset multiple of the average density of the pollutant in the ambient air as the test density, wherein the preset multiple is greater than 1;

[0020] Obtaining at least one first test result of at least one reagent type in the absence of contamination;

[0021] Using the pollutants to test at least one type of reagent respectively, and obtaining at least one second test result, wherein the density of the pollutants in the air in the test environment is the test density;

[0022] When the difference between the first test result and the second test result of the reagent type is greater than a preset value, the test of the reagent type is regarded as an abnormal test;

[0023] When there is an abnormal test in the test of at least one reagent type by the contaminant, the contaminant is regarded as a test contamination source.

[0024] Preferably, the calculation of the viscosity coefficient of the candidate material of the kit and the test pollution source comprises the following steps:

[0025] Use the alternative materials of the test kit to make alternative test strips, where the length and width of the alternative test strips are both preset lengths;

[0026] Use a test pollution source spray with a preset density to spray in a direction parallel to the surface of the candidate test paper, the spray volume is a preset volume, and the spray position is a fixed position;

[0027] Use the preset wind speed to clean the optional test paper after spraying, and the cleaning time is the preset time;

[0028] Obtain the test contamination source content in the candidate test strip after cleaning;

[0029] The viscosity coefficient is the result of dividing the test contamination source content by the area of ​​the alternative test paper.

[0030] Preferably, generating at least one candidate material combination of the kit comprises the following steps:

[0031] Selecting i candidate materials for the kit from at least one candidate material for the kit to form a combination of candidate materials for the kit, wherein the value of i ranges from 1 to n, and n is the total number of the at least one candidate material for the kit;

[0032] Assign usage ratios to each of the i kit alternative materials , ,…and ,in, , ,…and are all values ​​that satisfy the constraints, where: , , ,…and are all integer multiples of c, , ,…and The sum of is less than 1, c is the allowable error;

[0033] When i traverses from 1 to n, and the usage ratio of the i-test kit alternative materials is taken , ,…and When all possible values ​​of are considered, at least one candidate material combination for the kit is generated.

[0034] Preferably, the calculation of the comprehensive contamination residual coefficient of the candidate material combination of the kit based on the viscosity coefficient comprises the following steps:

[0035] Get the usage ratio of at least one of the kit alternative materials in the kit alternative material combination , ,…and ;

[0036] Use the residue formula to calculate the relative residue coefficient of the test kit candidate material combination with respect to the tested contamination source;

[0037] Taking the average of the relative residual coefficients of the candidate material combination of the kit with respect to at least one tested contamination source to obtain the comprehensive contamination residual coefficient of the candidate material combination of the kit;

[0038] The residual formula is as follows: ,

[0039] Among them, A is the relative residual coefficient of the combination of alternative materials in the test kit with respect to the test contamination source, is the usage ratio of the kth kit alternative material in the kit alternative material combination, is the viscosity coefficient between the kth candidate material in the candidate material combination of the kit and the test contamination source.

[0040] Preferably, the design of the external structure of the test kit based on the test capacity of the test kit comprises the following steps:

[0041] The first constraint of the test kit is that the test kit is a rectangular parallelepiped, the bottom of the test kit is a square, and the ratio of the height of the test kit to the length of the bottom of the test kit is the golden ratio. ;

[0042] Using the first constraint condition and the volume formula, the constrained volume of the test kit is calculated, and the constrained volume of the test kit is set equal to the test capacity, and the length of the bottom surface of the test kit and the height of the test kit are solved;

[0043] According to the obtained data, the dimensions of the external structure of the test kit are set;

[0044] The volume formula is as follows: ,

[0045] Wherein, V is the constraint volume of the reagent box, and a is the length of the bottom surface of the reagent box.

[0046] Preferably, the establishment of the hole sealing leakage model comprises the following steps:

[0047] Based on historical data, the value range of the side length of the reagent kit is obtained as the pore size range;

[0048] Divide the aperture range at equal intervals to obtain at least one distance point;

[0049] Under the condition that the hole diameter is the value at the distance point and the hole is sealed, the intrusion amount of air leaking into the test kit during the test kit test is obtained;

[0050] The distance points are paired with the intrusion amount and fitted to obtain the leakage fitting function, where the distance points are the independent variables and the intrusion amount is the dependent variable.

[0051] Preferably, the step of designing the number, position and diameter of the air inlet and the air outlet of the kit to obtain the design parameters of the air inlet and the air outlet comprises the following steps:

[0052] The diameters of the air inlet and the air outlet are set to be the same, both of which are target lengths, and the target length is substituted into the leakage fitting function to obtain the target leakage amount, wherein the target length is the larger one of the height of the reagent box and the length of the bottom surface of the reagent box;

[0053] Based on the historical data, a maximum allowable leakage amount is obtained, wherein the maximum allowable leakage amount is a critical value that affects the test results in the test kit;

[0054] Set the number of air inlet holes and air outlet holes to be the same, obtain the number of air inlet holes and air outlet holes, the number of air inlet holes and air outlet holes is the maximum value that satisfies the second constraint condition, and the second constraint condition is: , where e is the sum of the number of air inlet holes and air outlet holes, f is the target leakage, and g is the maximum allowable leakage;

[0055] Select two parallel sides of the reagent box as the first side and the second side;

[0056] The first side surface is divided into at least one partial block, the number of the partial blocks is equal to the number of the air inlet holes, and the center of the air inlet hole is set at the center of the partial block;

[0057] The projection position of the air inlet on the second side surface is used as the position of the air outlet.

[0058] Preferably, the designing of the blocking block for blocking the air inlet and the air outlet based on the design parameters of the air inlet and the air outlet comprises the following steps:

[0059] Using the actual production material of the test kit as the production material of the plugging block;

[0060] The blocking block is composed of a cap and a blocking column, the diameter of the blocking column is consistent with the apertures of the corresponding air inlet and outlet holes, and the diameter of the cap is larger than the diameter of the blocking column.

[0061] A reagent kit design system for preventing external contamination and interference, used to implement the above-mentioned reagent kit design method for preventing external contamination and interference, comprising:

[0062] A data acquisition module, the data acquisition module acquires at least one reagent type tested using the test kit, and acquires at least one test contamination source that affects the test result of the reagent type based on the big data;

[0063] A data calculation module, which obtains at least one candidate material of the test kit based on the big data and calculates the viscosity coefficient between the candidate material of the test kit and the test contamination source;

[0064] A combination generation module, wherein the combination generation module generates at least one kit candidate material combination, wherein the kit candidate material combination is composed of at least one kit candidate material and a usage ratio of the kit candidate material;

[0065] A coefficient calculation module, wherein the coefficient calculation module calculates a comprehensive contamination residual coefficient of a combination of candidate materials of the kit based on a viscosity coefficient;

[0066] A combination selection module, wherein the combination selection module selects a combination of candidate materials of the test kit with the smallest comprehensive contamination residual coefficient as a target combination of candidate materials of the test kit;

[0067] A material generation module, wherein the material generation module uses at least one candidate material of the target kit candidate material combination, heats and mixes the candidate materials according to the usage ratio of the candidate materials, and generates actual production materials of the kit;

[0068] An architecture determination module, which designs the appearance structure of the test kit based on the test capacity of the test kit to obtain the appearance architecture of the test kit;

[0069] A model building module, wherein the model building module builds a hole sealing leakage model;

[0070] A hole design module, which designs the number, position and aperture of the air inlet and air outlet of the test kit based on the test kit appearance structure and the hole sealing leakage model, and obtains the design parameters of the air inlet and air outlet, wherein the aperture is the diameter;

[0071] A sealing design module is used to design a blocking block for blocking the air inlet and the air outlet based on the design parameters of the air inlet and the air outlet.

[0072] Compared with the prior art, the present invention has the following beneficial effects:

[0073] By setting up a coefficient calculation module, a data calculation module, a model building module and a hole design module, the test kit designed in this way can discharge the air with pollution sources inside it through air exchange, and due to the setting of its material, the residual amount of pollution sources adhering to the inside of the test kit is small, and will not have an observable impact on the test results of the test kit. Therefore, during the test, it can be guaranteed to a large extent that the test of the test kit is not interfered by the pollution source, thereby ensuring the accuracy of the test results, making the test have a higher credibility. BRIEF DESCRIPTION OF THE DRAWINGS

[0074] Figure 1 A schematic diagram of the process of designing a kit for preventing external contamination interference of the present invention;

[0075] Figure 2 A schematic diagram of a process for obtaining at least one test contamination source that affects test results of a reagent type based on big data according to the present invention;

[0076] Figure 3 A schematic diagram of the process of calculating the viscosity coefficient of the candidate materials of the kit and testing the pollution source of the present invention;

[0077] Figure 4 A schematic diagram of a process for generating at least one candidate material combination for a kit of the present invention;

[0078] Figure 5It is a schematic diagram of a process for calculating the comprehensive contamination residual coefficient of the candidate material combination of the kit based on the viscosity coefficient of the present invention;

[0079] Figure 6 The figure is a schematic diagram of a process for designing the external structure of the test kit based on the test capacity of the test kit of the present invention;

[0080] Figure 7 A schematic diagram of the process of establishing a hole sealing leakage model of the present invention;

[0081] Figure 8 A schematic diagram of a process for designing the number, position and diameter of the air inlet and outlet holes of the reagent kit of the present invention to obtain the design parameters of the air inlet and outlet holes;

[0082] Fig. 9 The present invention is a schematic diagram of a process for designing a blocking block for blocking an air inlet and an air outlet based on the design parameters of the air inlet and the air outlet. DETAILED DESCRIPTION

[0083] The following description is used to disclose the present invention so that those skilled in the art can implement the present invention. The preferred embodiments described below are only examples, and those skilled in the art may think of other obvious variations.

[0084] Reference Figure 1 As shown, a method for designing a kit to prevent external contamination interference comprises:

[0085] Obtain at least one reagent type to be tested using the test kit, and based on the big data, obtain at least one test contamination source that affects the test result of the reagent type;

[0086] Based on the big data, at least one candidate material of the test kit is obtained, and the viscosity coefficient between the candidate material of the test kit and the test contamination source is calculated;

[0087] generating at least one candidate material combination for a test kit, wherein the candidate material combination for a test kit is composed of at least one candidate material for a test kit and a usage ratio of the candidate material for the test kit;

[0088] Based on the viscosity coefficient, the comprehensive contamination residual coefficient of the candidate material combination of the kit is calculated;

[0089] Select the candidate material combination of the test kit with the smallest comprehensive contamination residual coefficient as the candidate material combination of the target test kit;

[0090] Using at least one candidate material of the target kit candidate material combination, heating and mixing according to the usage ratio of the candidate materials of the kit to generate actual production materials of the kit;

[0091] Based on the test capacity of the test kit, the appearance structure of the test kit is designed to obtain the appearance architecture of the test kit;

[0092] Establish a hole sealing leakage model;

[0093] Based on the test kit appearance structure and the hole sealing leakage model, the number, position and aperture of the air inlet and air outlet of the test kit are designed to obtain the design parameters of the air inlet and air outlet, where the aperture is the diameter;

[0094] Based on the design parameters of the air inlet and the air outlet, a blocking block for blocking the air inlet and the air outlet is designed.

[0095] In this scheme, the test kit is designed so that it can prevent external pollution interference. The idea of ​​this scheme is to replace the air inside the test kit, that is, to replace the air inside the test kit with pollution-free purified air from the air inlet and discharge it from the air outlet, thereby completing the discharge of the pollution source. However, since the pollution source will adhere to the inner wall of the test kit, it is necessary to set the material of the test kit so that the amount of pollution source adhesion is small, so that after the air is discharged, the pollution source residue inside the test kit is small and will not have much impact on the test. In addition, since ventilation is required, air inlets and outlets are set. Although the air inlets and outlets are blocked after ventilation, there will still be a small amount of external air intrusion. At the same time, when ventilating, it is necessary to make the airflow generated by it cover as much as possible the inside of the test kit, thereby being able to more thoroughly discharge the pollution source adhering to the inner wall of the test kit.

[0096] Reference Figure 2 As shown, based on big data, obtaining at least one test contamination source that affects the test results of the reagent type includes the following steps:

[0097] Acquire at least one pollutant in the ambient air whose average density is greater than a preset ratio;

[0098] Taking a preset multiple of the average density of the pollutant in the ambient air as the test density, wherein the preset multiple is greater than 1;

[0099] Obtaining at least one first test result of at least one reagent type in the absence of contamination;

[0100] Using the pollutants to test at least one type of reagent respectively, and obtaining at least one second test result, wherein the density of the pollutants in the air in the test environment is the test density;

[0101] When the difference between the first test result and the second test result of the reagent type is greater than a preset value, the test of the reagent type is regarded as an abnormal test;

[0102] When there is an abnormal test in the test of at least one reagent type by the contaminant, the contaminant is regarded as a test contamination source.

[0103] There are many pollution sources in the air. In order to facilitate the setting of materials, we ignore the pollution sources that have little impact on the test results and only consider the pollution sources with greater impact. This can relatively simplify the calculation of parameters.

[0104] Reference Figure 3 As shown, calculating the viscosity coefficient of the candidate material of the kit and the test contamination source includes the following steps:

[0105] Use the alternative materials of the test kit to make alternative test strips, where the length and width of the alternative test strips are both preset lengths;

[0106] Use a test pollution source spray with a preset density to spray in a direction parallel to the surface of the candidate test paper, the spray volume is a preset volume, and the spray position is a fixed position;

[0107] Use the preset wind speed to clean the optional test paper after spraying, and the cleaning time is the preset time;

[0108] Obtain the test contamination source content in the candidate test strip after cleaning;

[0109] The viscosity coefficient is the result of dividing the test contamination source content by the area of ​​the alternative test paper.

[0110] Each pollution source has a different degree of adhesion to the alternative materials, so it is necessary to use the viscosity coefficient to evaluate it. In actual situations, different pollution sources will be dealt with. Therefore, in order to make the overall adhesion of the test kit to various pollution sources low, it is necessary to comprehensively consider the adhesion of the alternative materials to different pollution sources, and then obtain the required material composition of the test kit.

[0111] Reference Figure 4 As shown, generating at least one candidate material combination of the kit includes the following steps:

[0112] Selecting i candidate materials for the kit from at least one candidate material for the kit to form a combination of candidate materials for the kit, wherein the value of i ranges from 1 to n, and n is the total number of the at least one candidate material for the kit;

[0113] Assign usage ratios to each of the i kit alternative materials , ,…and ,in, , ,…and are all values ​​that satisfy the constraints, where: , , ,…and are all integer multiples of c, , ,…and The sum of is less than 1, c is the allowable error;

[0114] When i traverses from 1 to n, and the usage ratio of the i-test kit alternative materials is taken , ,…and When all possible values ​​of are considered, at least one candidate material combination for the kit is generated.

[0115] Here, the proportion of i candidate materials in the kit can be adjusted. Therefore, in order to consider their different proportions, the restriction condition is used to obtain , ,…and All possible values ​​of , but here , ,…and are all integer multiples of c, so their possible values ​​can be limited to finite cases. When c is set small enough as the allowable error, the generated , ,…and The proportion of any one of the i reagent kit alternative materials in the reagent kit can be approximated to meet the accuracy requirements, so at least one combination of reagent kit alternative materials obtained thereby can represent all possibilities.

[0116] Reference Figure 5 As shown, based on the viscosity coefficient, the calculation of the comprehensive contamination residual coefficient of the candidate material combination of the kit includes the following steps:

[0117] Get the usage ratio of at least one of the kit alternative materials in the kit alternative material combination , ,…and ;

[0118] Use the residue formula to calculate the relative residue coefficient of the test kit candidate material combination with respect to the tested contamination source;

[0119] Taking the average of the relative residual coefficients of the candidate material combination of the kit with respect to at least one tested contamination source to obtain the comprehensive contamination residual coefficient of the candidate material combination of the kit;

[0120] The residual formula is as follows: ,

[0121] Among them, A is the relative residual coefficient of the combination of alternative materials in the test kit with respect to the test contamination source, is the usage ratio of the kth kit alternative material in the kit alternative material combination, is the viscosity coefficient between the kth candidate material in the candidate material combination of the kit and the test contamination source.

[0122] Since there are multiple test contamination sources, it is necessary to calculate the relative residual coefficient of the alternative material combination of the test kit for each test contamination source. In addition, in order to take all test contamination sources into consideration, the relative residual coefficients of the alternative material combination of the test kit for at least one test contamination source are averaged, and then the comprehensive contamination residual coefficient takes into account all test contamination sources, and the result has a high reference value.

[0123] Reference Figure 6 As shown, based on the test capacity of the test kit, designing the appearance structure of the test kit includes the following steps:

[0124] The first constraint of the test kit is that the test kit is a rectangular parallelepiped, the bottom of the test kit is a square, and the ratio of the height of the test kit to the length of the bottom of the test kit is the golden ratio. ;

[0125] Using the first constraint condition and the volume formula, the constrained volume of the test kit is calculated, and the constrained volume of the test kit is set equal to the test capacity, and the length of the bottom surface of the test kit and the height of the test kit are solved;

[0126] According to the obtained data, the dimensions of the external structure of the test kit are set;

[0127] The volume formula is as follows: ,

[0128] Wherein, V is the constraint volume of the reagent box, and a is the length of the bottom surface of the reagent box.

[0129] The golden ratio is used to make the overall shape of the test kit more beautiful.

[0130] Reference Figure 7 As shown in the figure, establishing the hole sealing leakage model includes the following steps:

[0131] Based on historical data, the value range of the side length of the reagent kit is obtained as the pore size range;

[0132] Divide the aperture range at equal intervals to obtain at least one distance point;

[0133] Under the condition that the hole diameter is the value at the distance point and the hole is sealed, the intrusion amount of air leaking into the test kit during the test kit test is obtained;

[0134] The distance points are paired with the intrusion amount and fitted to obtain the leakage fitting function, where the distance points are the independent variables and the intrusion amount is the dependent variable.

[0135] The leakage fitting function can predict the leakage of different apertures, and then assist in setting the number of subsequent holes.

[0136] Reference Figure 8 As shown, the number, position and diameter of the air inlet and outlet holes of the test kit are designed to obtain the design parameters of the air inlet and outlet holes, including the following steps:

[0137] The diameters of the air inlet and the air outlet are set to be the same, both of which are target lengths, and the target length is substituted into the leakage fitting function to obtain the target leakage amount, wherein the target length is the larger one of the height of the reagent box and the length of the bottom surface of the reagent box;

[0138] Based on the historical data, a maximum allowable leakage amount is obtained, wherein the maximum allowable leakage amount is a critical value that affects the test results in the test kit;

[0139] Set the number of air inlet holes and air outlet holes to be the same, obtain the number of air inlet holes and air outlet holes, the number of air inlet holes and air outlet holes is the maximum value that satisfies the second constraint condition, and the second constraint condition is: , where e is the sum of the number of air inlet holes and air outlet holes, f is the target leakage, and g is the maximum allowable leakage;

[0140] Select two parallel sides of the reagent box as the first side and the second side;

[0141] The first side surface is divided into at least one partial block, the number of the partial blocks is equal to the number of the air inlet holes, and the center of the air inlet hole is set at the center of the partial block;

[0142] The projection position of the air inlet on the second side surface is used as the position of the air outlet.

[0143] The main limitation of the setting of the air inlet and outlet holes is that the airflow generated by them must be able to cover the internal space of the test kit as much as possible, thereby improving the degree of discharge of the pollution sources adhering to the inside of the test kit. At the same time, it is also necessary to limit the air that leaks into the test kit after the holes are sealed, so as to avoid the pollution sources in the invading air from having an observable impact on the test results.

[0144] Reference Fig. 9 As shown, based on the design parameters of the air inlet and the air outlet, designing a blocking block for blocking the air inlet and the air outlet includes the following steps:

[0145] Using the actual production material of the test kit as the production material of the plugging block;

[0146] The blocking block is composed of a cap and a blocking column, the diameter of the blocking column is consistent with the apertures of the corresponding air inlet and outlet holes, and the diameter of the cap is larger than the diameter of the blocking column.

[0147] A reagent kit design system for preventing external contamination and interference, used to implement the above-mentioned reagent kit design method for preventing external contamination and interference, comprising:

[0148] A data acquisition module, the data acquisition module acquires at least one reagent type tested using the test kit, and acquires at least one test contamination source that affects the test result of the reagent type based on the big data;

[0149] A data calculation module, which obtains at least one candidate material of the test kit based on the big data and calculates the viscosity coefficient between the candidate material of the test kit and the test contamination source;

[0150] A combination generation module, wherein the combination generation module generates at least one kit candidate material combination, wherein the kit candidate material combination is composed of at least one kit candidate material and a usage ratio of the kit candidate material;

[0151] A coefficient calculation module, wherein the coefficient calculation module calculates a comprehensive contamination residual coefficient of a combination of candidate materials of the kit based on a viscosity coefficient;

[0152] A combination selection module, wherein the combination selection module selects a combination of candidate materials of the test kit with the smallest comprehensive contamination residual coefficient as a target combination of candidate materials of the test kit;

[0153] A material generation module, wherein the material generation module uses at least one candidate material of the target kit candidate material combination, heats and mixes the candidate materials according to the usage ratio of the candidate materials, and generates actual production materials of the kit;

[0154] An architecture determination module, which designs the appearance structure of the test kit based on the test capacity of the test kit to obtain the appearance architecture of the test kit;

[0155] A model building module, wherein the model building module builds a hole sealing leakage model;

[0156] A hole design module, which designs the number, position and aperture of the air inlet and air outlet of the test kit based on the test kit appearance structure and the hole sealing leakage model, and obtains the design parameters of the air inlet and air outlet, wherein the aperture is the diameter;

[0157] A sealing design module is used to design a blocking block for blocking the air inlet and the air outlet based on the design parameters of the air inlet and the air outlet.

[0158] Furthermore, the present solution also proposes a storage medium on which a computer-readable program is stored, and when the computer-readable program is called, the above-mentioned method for designing a reagent kit to prevent external contamination interference is executed.

[0159] It is understandable that the storage medium may be a magnetic medium, such as a floppy disk, a hard disk, or a magnetic tape; an optical medium, such as a DVD; or a semiconductor medium, such as a solid state drive (SSD).

[0160] In summary, the advantages of the present invention are: by setting a coefficient calculation module, a data calculation module, a model building module and a hole design module, the test kit designed in this way can discharge the air with pollution sources inside it through air exchange, and due to the setting of its material, the residual amount of pollution sources adhering to the inside of the test kit is small, and will not have an observable impact on the test results of the test kit. Therefore, during the test, it can be guaranteed to a large extent that the test of the test kit is not interfered by the pollution source, thereby ensuring the accuracy of the test results, so that the test has a higher credibility.

[0161] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited to the above embodiments. The above embodiments and descriptions only describe the principles of the present invention. The present invention may be subject to various changes and improvements without departing from the spirit and scope of the present invention. These changes and improvements fall within the scope of the present invention. The scope of protection claimed by the present invention is defined by the attached claims and their equivalents.

Claims

1. A method for designing a kit to prevent external contamination interference, characterized in that: include: Obtain at least one reagent type to be tested using the test kit, and based on the big data, obtain at least one test contamination source that affects the test result of the reagent type; Based on the big data, at least one candidate material of the test kit is obtained, and the viscosity coefficient between the candidate material of the test kit and the test contamination source is calculated; generating at least one candidate material combination for a test kit, wherein the candidate material combination for a test kit is composed of at least one candidate material for a test kit and a usage ratio of the candidate material for the test kit; Based on the viscosity coefficient, the comprehensive contamination residual coefficient of the candidate material combination of the kit is calculated; Select the candidate material combination of the test kit with the smallest comprehensive contamination residual coefficient as the candidate material combination of the target test kit; Using at least one candidate material of the target kit candidate material combination, heating and mixing according to the usage ratio of the candidate materials of the kit to generate actual production materials of the kit; Based on the test capacity of the test kit, the appearance structure of the test kit is designed to obtain the appearance architecture of the test kit; Establish a hole sealing leakage model; Based on the test kit appearance structure and the hole sealing leakage model, the number, position and aperture of the air inlet and air outlet of the test kit are designed to obtain the design parameters of the air inlet and air outlet, where the aperture is the diameter; Based on the design parameters of the air inlet and the air outlet, a blocking block for blocking the air inlet and the air outlet is designed.

2. The method for designing a kit to prevent external contamination according to claim 1, characterized in that: The method of obtaining at least one test contamination source that affects the test results of the reagent type based on the big data comprises the following steps: Acquire at least one pollutant in the ambient air whose average density is greater than a preset ratio; Taking a preset multiple of the average density of the pollutant in the ambient air as the test density, wherein the preset multiple is greater than 1; Obtaining at least one first test result of at least one reagent type in the absence of contamination; Using the pollutants to test at least one type of reagent respectively, and obtaining at least one second test result, wherein the density of the pollutants in the air in the test environment is the test density; When the difference between the first test result and the second test result of the reagent type is greater than a preset value, the test of the reagent type is regarded as an abnormal test; When there is an abnormal test in the test of at least one reagent type by the contaminant, the contaminant is regarded as a test contamination source.

3. The method for designing a kit to prevent external contamination according to claim 2, characterized in that: The calculation of the viscosity coefficient of the candidate material of the kit and the test pollution source comprises the following steps: Use the alternative materials of the test kit to make alternative test strips, where the length and width of the alternative test strips are both preset lengths; Use a test pollution source spray with a preset density to spray in a direction parallel to the surface of the candidate test paper, the spray volume is a preset volume, and the spray position is a fixed position; Use the preset wind speed to clean the optional test paper after spraying, and the cleaning time is the preset time; Obtain the test contamination source content in the candidate test strip after cleaning; The viscosity coefficient is the result of dividing the test contamination source content by the area of ​​the alternative test paper.

4. The method for designing a kit to prevent external contamination according to claim 3, characterized in that: The generating of at least one candidate material combination of the kit comprises the following steps: Selecting i candidate materials for the kit from at least one candidate material for the kit to form a combination of candidate materials for the kit, wherein the value of i ranges from 1 to n, and n is the total number of the at least one candidate material for the kit; Assign usage ratios to each of the i kit alternative materials , ,…and ,in, , ,…and are all values ​​that satisfy the constraints, where: , , ,…and are all integer multiples of c, , ,…and The sum of is less than 1, c is the allowable error; When i traverses from 1 to n, and the usage ratio of the i-test kit alternative materials is taken , ,…and When all possible values ​​of are considered, at least one candidate material combination for the kit is generated.

5. The method for designing a kit to prevent external contamination according to claim 4, characterized in that: The method of calculating the comprehensive contamination residual coefficient of the candidate material combination of the kit based on the viscosity coefficient comprises the following steps: Get the usage ratio of at least one of the kit alternative materials in the kit alternative material combination , ,…and ; Use the residue formula to calculate the relative residue coefficient of the test kit candidate material combination with respect to the tested contamination source; Taking the average of the relative residual coefficients of the candidate material combination of the kit with respect to at least one tested contamination source to obtain the comprehensive contamination residual coefficient of the candidate material combination of the kit; The residual formula is as follows: , Among them, A is the relative residual coefficient of the combination of alternative materials in the test kit with respect to the test contamination source, is the usage ratio of the kth kit alternative material in the kit alternative material combination, is the viscosity coefficient between the kth candidate material in the candidate material combination of the kit and the test contamination source.

6. The method for designing a kit to prevent external contamination according to claim 5, characterized in that: The design of the test kit appearance structure based on the test capacity of the test kit includes the following steps: The first constraint of the test kit is that the test kit is a rectangular parallelepiped, the bottom of the test kit is a square, and the ratio of the height of the test kit to the length of the bottom of the test kit is the golden ratio. ; Using the first constraint condition and the volume formula, the constrained volume of the test kit is calculated, and the constrained volume of the test kit is set equal to the test capacity, and the length of the bottom surface of the test kit and the height of the test kit are solved; According to the obtained data, the dimensions of the external structure of the test kit are set; The volume formula is as follows: , Wherein, V is the constraint volume of the reagent box, and a is the length of the bottom surface of the reagent box.

7. The method for designing a kit to prevent external contamination according to claim 6, characterized in that: The hole sealing leakage model is established, comprising the following steps: Based on historical data, the value range of the side length of the reagent kit is obtained as the pore size range; Divide the aperture range at equal intervals to obtain at least one distance point; Under the condition that the hole diameter is the value at the distance point and the hole is sealed, the intrusion amount of air leaking into the test kit during the test kit test is obtained; The distance points are paired with the intrusion amount and fitted to obtain the leakage fitting function, where the distance points are the independent variables and the intrusion amount is the dependent variable.

8. The method for designing a kit to prevent external contamination according to claim 7, characterized in that: The step of designing the number, position and diameter of the air inlet and air outlet of the kit to obtain the design parameters of the air inlet and air outlet comprises the following steps: The diameters of the air inlet and the air outlet are set to be the same, both of which are target lengths, and the target length is substituted into the leakage fitting function to obtain the target leakage amount, wherein the target length is the larger one of the height of the reagent box and the length of the bottom surface of the reagent box; Based on the historical data, a maximum allowable leakage amount is obtained, wherein the maximum allowable leakage amount is a critical value that affects the test results in the test kit; Set the number of air inlet holes and air outlet holes to be the same, obtain the number of air inlet holes and air outlet holes, the number of air inlet holes and air outlet holes is the maximum value that satisfies the second constraint condition, and the second constraint condition is: , where e is the sum of the number of air inlet holes and air outlet holes, f is the target leakage, and g is the maximum allowable leakage; Select two parallel sides of the reagent box as the first side and the second side; The first side surface is divided into at least one partial block, the number of the partial blocks is equal to the number of the air inlet holes, and the center of the air inlet hole is set at the center of the partial block; The projection position of the air inlet on the second side surface is used as the position of the air outlet.

9. The method for designing a kit to prevent external contamination according to claim 8, characterized in that: The design of the blocking block for blocking the air inlet and the air outlet based on the design parameters of the air inlet and the air outlet comprises the following steps: Using the actual production material of the test kit as the production material of the plugging block; The blocking block is composed of a cap and a blocking column, the diameter of the blocking column is consistent with the apertures of the corresponding air inlet and outlet holes, and the diameter of the cap is larger than the diameter of the blocking column.

10. A system for designing a reagent kit to prevent external contamination interference, used to implement the method for designing a reagent kit to prevent external contamination interference as claimed in any one of claims 1 to 9, characterized in that: include: A data acquisition module, the data acquisition module acquires at least one reagent type tested using the test kit, and acquires at least one test contamination source that affects the test result of the reagent type based on the big data; A data calculation module, which obtains at least one candidate material of the test kit based on the big data and calculates the viscosity coefficient between the candidate material of the test kit and the test contamination source; A combination generation module, wherein the combination generation module generates at least one kit candidate material combination, wherein the kit candidate material combination is composed of at least one kit candidate material and a usage ratio of the kit candidate material; A coefficient calculation module, wherein the coefficient calculation module calculates a comprehensive contamination residual coefficient of a combination of candidate materials of the kit based on a viscosity coefficient; A combination selection module, wherein the combination selection module selects a combination of candidate materials of the test kit with the smallest comprehensive contamination residual coefficient as a target combination of candidate materials of the test kit; A material generation module, wherein the material generation module uses at least one candidate material of the target kit candidate material combination, heats and mixes the candidate materials according to the usage ratio of the candidate materials, and generates actual production materials of the kit; An architecture determination module, wherein the architecture determination module designs the appearance structure of the test kit based on the test capacity of the test kit to obtain the appearance architecture of the test kit; A model building module, wherein the model building module builds a hole sealing leakage model; A hole design module, which designs the number, position and aperture of the air inlet and air outlet of the test kit based on the test kit appearance structure and the hole sealing leakage model, and obtains the design parameters of the air inlet and air outlet, wherein the aperture is the diameter; A sealing design module is used to design a blocking block for blocking the air inlet and the air outlet based on the design parameters of the air inlet and the air outlet.

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