Femtosecond laser refractive surgery parameter optimization method and device, medium and product

Abstract

The invention discloses a femtosecond laser refractive operation parameter optimization method and device, a medium and a product, and relates to the field of refractive operation parameter optimization. Refractive operation parameters such as the diameter of an optical area and the thickness of a lens substrate are automatically designed according to parameters such as the diopter, the pupil diameter, the cornea center thickness and the predicted cornea cutting thickness of a patient; when the pupil diameter of a patient is large, the diameter of the optical area is increased as much as possible on the premise that the cornea biomechanical property after an operation is guaranteed. When the degree of the patient is high or low, all parameters are comprehensively considered to optimize the diameter of the optical zone. According to the method, corneal refraction operation parameters such as the optical area of the patient and the thickness of the lens substrate can be automatically optimized, automatic personalized design can be achieved, the postoperative visual quality and corneal biomechanical characteristics of the patient are comprehensively considered, the optimization accuracy is improved, the working intensity of doctors is reduced, and the working efficiency is improved.

Description

Technical Field

[0001] The present application relates to the field of refractive surgery parameter optimization, and in particular to a femtosecond laser refractive surgery parameter optimization method, device, medium and product. Background Art

[0002] Femtosecond laser refractive lens extraction is a laser corneal refractive surgery that uses a femtosecond laser to make a lens on the cornea. Removing the lens can change the corneal curvature, thereby correcting refractive errors such as myopia and astigmatism. There is a large demand for myopia correction in my country, and this refractive surgery method is in great demand. The design of surgical parameters requires doctors to comprehensively consider the thickness of the human cornea, pupil diameter, refractive power, etc. to design personalized surgical parameters. Unreasonable surgical parameter design may cause postoperative visual quality problems and complications such as postoperative corneal dilatation. For example, if the patient's pupil diameter is large but the diameter of the optical zone designed for surgery is too small, it may cause visual symptoms such as night glare after surgery; if the patient has a high degree but the corneal thickness is thin, if a larger optical zone diameter is used, it may cause a decrease in postoperative biomechanical properties, and then there is a risk of postoperative corneal dilatation. Therefore, the reasonable optimization design of surgical parameters is crucial to ensure postoperative visual quality and postoperative safety. Comprehensive consideration of various parameters and optimization and adjustment require doctors to have sufficient experience and a certain learning curve. Summary of the invention

[0003] The purpose of this application is to provide a femtosecond laser refractive surgery parameter optimization method, device, medium and product to improve the accuracy of parameter optimization and the doctor's work efficiency.

[0004] To achieve the above objectives, this application provides the following solutions:

[0005] In a first aspect, the present application provides a method for optimizing parameters of femtosecond laser refractive surgery, comprising:

[0006] Obtain the patient's pupil diameter;

[0007] Determine whether the pupil diameter is greater than a pupil diameter setting value, and obtain a first determination result;

[0008] If the first judgment result is yes, adjusting the optical zone according to the expected corneal ablation thickness and the residual stromal bed thickness;

[0009] If the first judgment result is no, the optical zone is adjusted according to the expected corneal ablation thickness.

[0010] Optionally, the optical zone is adjusted based on the expected corneal ablation thickness and residual stromal bed thickness, including:

[0011] Increase the optical area;

[0012] Determine the corneal estimated ablation thickness and the residual stromal bed thickness according to the current optical zone diameter; the corneal estimated ablation thickness is determined according to the optical zone diameter and the diopter; the residual stromal bed thickness is determined according to the corneal central thickness, the corneal estimated ablation thickness and the corneal cap;

[0013] Determine whether the residual stromal bed thickness is less than a set thickness or whether the ratio of the estimated corneal ablation thickness to the corneal central thickness is greater than a set ratio, and obtain a second determination result;

[0014] If the second judgment result is yes, the current optical zone diameter is adjusted down by a preset adjustment amount, and the process returns to "determining the estimated corneal ablation thickness and the residual stromal bed thickness according to the current optical zone diameter".

[0015] Optionally, the optical zone diameter is less than or equal to a set optical zone diameter.

[0016] Optionally, the optical zone is adjusted according to the expected corneal ablation thickness, including:

[0017] Determining whether the estimated corneal ablation thickness is greater than the maximum allowable corneal ablation thickness; the estimated corneal ablation thickness is determined based on the optical zone diameter and the diopter;

[0018] If yes, the current optical zone diameter is reduced by a preset adjustment amount, and the process returns to “determining whether the estimated corneal cutting thickness is greater than the maximum allowable corneal cutting thickness”;

[0019] If not, the current optical zone diameter is not adjusted.

[0020] Optionally, it also includes:

[0021] Determine whether the estimated corneal cutting thickness is less than the recommended cutting thickness value to obtain a third determination result;

[0022] If the third judgment result is yes, the current optical zone diameter is increased by a preset adjustment amount, and it is determined whether the current optical zone diameter is equal to the optical zone set diameter, to obtain a fourth judgment result;

[0023] If the fourth judgment result is yes, the lens base is increased by the set value, and the process returns to "determine whether the corneal estimated cutting thickness is less than the cutting thickness recommended value"; if the fourth judgment result is no, the process returns directly to "determine whether the corneal estimated cutting thickness is less than the cutting thickness recommended value";

[0024] If the third judgment result is no, the current optical zone diameter is not adjusted.

[0025] Optionally, the maximum allowable corneal ablation thickness = central corneal thickness × set ratio.

[0026] In a second aspect, the present application provides a computer device, comprising: a memory, a processor, and a computer program stored in the memory and executable on the processor, wherein the processor executes the computer program to implement any of the femtosecond laser refractive surgery parameter optimization methods described above.

[0027] In a third aspect, the present application provides a computer-readable storage medium having a computer program stored thereon, which, when executed by a processor, implements any of the femtosecond laser refractive surgery parameter optimization methods described above.

[0028] In a fourth aspect, the present application provides a computer program product, including a computer program, which, when executed by a processor, implements any of the femtosecond laser refractive surgery parameter optimization methods described above.

[0029] According to the specific embodiments provided in this application, this application discloses the following technical effects:

[0030] The present application provides a femtosecond laser refractive surgery parameter optimization method, device, medium and product, by obtaining the patient's pupil diameter. It is judged whether the pupil diameter is greater than the pupil diameter setting value to obtain a first judgment result. If the first judgment result is yes, the optical zone is adjusted according to the expected corneal cutting thickness and the residual stromal bed thickness. If the first judgment result is no, the optical zone is adjusted according to the expected corneal cutting thickness. The present application can automatically optimize the patient's optical zone, improve the optimization accuracy, reduce the doctor's workload, and improve work efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0032] Figure 1 A flowchart of a femtosecond laser refractive surgery parameter optimization method provided in one embodiment of the present application. DETAILED DESCRIPTION

[0033] The following will be combined with the drawings in the embodiments of the present application to clearly and completely describe the technical solutions in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.

[0034] In order to make the above-mentioned objects, features and advantages of the present application more obvious and easy to understand, the present application is further described in detail below with reference to the accompanying drawings and specific implementation methods.

[0035] The present application provides a femtosecond laser refractive surgery parameter optimization method, which automatically considers various parameters of the human eye for personalized parameter adjustment. The femtosecond laser refractive surgery equipment can use this method to automatically perform personalized parameter design on surgical parameters, saving doctors’ surgical design time, shortening the learning curve for doctors to optimize refractive surgery parameters, improving the accuracy of parameter optimization, and improving the work efficiency of doctors in refractive surgery parameter design.

[0036] In an exemplary embodiment, Figure 1 As shown, a femtosecond laser refractive surgery parameter optimization method is provided, comprising the following steps:

[0037] S1: Get the patient's pupil diameter.

[0038] S2: Determine whether the pupil diameter is greater than a pupil diameter setting value, and obtain a first determination result.

[0039] S3: If the first judgment result is yes, the optical zone is adjusted according to the expected corneal ablation thickness and the residual stromal bed thickness. The optical zone diameter is less than or equal to the optical zone set diameter. In this embodiment, the optical zone set diameter is 7 mm.

[0040] As an optional embodiment, the optical zone is adjusted according to the expected corneal ablation thickness and the residual stromal bed thickness, specifically including:

[0041] Increase the optical area.

[0042] The corneal expected ablation thickness and the residual stromal bed thickness are determined according to the current optical zone diameter. The corneal expected ablation thickness is determined according to the optical zone diameter and the diopter; the residual stromal bed thickness is determined according to the corneal central thickness, the corneal expected ablation thickness and the corneal cap.

[0043] It is determined whether the residual stromal bed thickness is less than a set thickness or whether the ratio of the estimated corneal ablation thickness to the central corneal thickness is greater than a set ratio, to obtain a second determination result; the set thickness is 280 μm.

[0044] If the second judgment result is yes, the current optical zone diameter is reduced by a preset adjustment amount (in this embodiment, the preset adjustment amount is 0.1 mm), and the program returns to "determine the expected corneal ablation thickness and the residual stromal bed thickness based on the current optical zone diameter".

[0045] In actual application, when the pupil diameter is larger than the pupil diameter setting value (the pupil diameter setting value is determined according to the pupil diameter measurement method. Because the normal distribution of pupil diameter measured by different measuring equipment under different test environment background illumination intensities is different, the user can set it independently here according to the actual situation), the optical zone is adjusted to increase by the preset adjustment amount of 0.1mm in sequence, and the corneal estimated ablation thickness and residual stromal bed thickness are calculated to determine the residual stromal thickness (RST) at this time. When RST is less than 280μm or PTA (the ratio of corneal estimated ablation thickness to corneal central thickness before ablation) is greater than 28%, the optical zone is stopped from being increased, and the optical zone is adjusted down by 0.1mm until PTA is less than 28% or RST is greater than 280μm. The maximum allowable range of the optical zone is recommended to be less than 7.00mm, which can also be set by the doctor.

[0046] S4: If the first judgment result is no, adjusting the optical zone according to the expected corneal ablation thickness.

[0047] As an optional implementation, the optical zone is adjusted according to the expected corneal ablation thickness, specifically including:

[0048] Determine whether the estimated corneal cutting thickness is greater than the maximum allowable corneal cutting thickness; the estimated corneal cutting thickness is determined based on the optical zone diameter and the diopter; the maximum allowable corneal cutting thickness = corneal central thickness × set ratio, in this application, the set ratio is 0.28. The diopter only takes pure spherical power as an example. If the cylindrical power is included, the calculation method is similar. The calculation of the estimated corneal cutting thickness may be different depending on the surgical equipment.

[0049] If so, the current optical zone diameter is reduced by a preset adjustment amount, and the process returns to "determining whether the estimated corneal cutting thickness is greater than the maximum allowable corneal cutting thickness".

[0050] If not, the current optical zone diameter is not adjusted.

[0051] In actual application, the diameter of the optical zone is gradually increased until the expected corneal ablation thickness is greater than the maximum allowable corneal ablation thickness, at which time the diameter of the optical zone is reduced by 0.1 mm.

[0052] It is determined whether the estimated corneal cutting thickness is less than the recommended cutting thickness value to obtain a third determination result.

[0053] If the third judgment result is yes, the current optical zone diameter is increased by a preset adjustment amount, and it is determined whether the current optical zone diameter is equal to the optical zone set diameter to obtain a fourth judgment result.

[0054] If the fourth judgment result is yes, the lens base is increased by a set value, and the process returns to "determine whether the corneal estimated cutting thickness is less than the cutting thickness recommended value"; if the fourth judgment result is no, the process returns directly to "determine whether the corneal estimated cutting thickness is less than the cutting thickness recommended value". The set value is 5 microns.

[0055] If the third judgment result is no, the current optical zone diameter is not adjusted.

[0056] In actual application, when the expected corneal cutting thickness is less than the recommended cutting thickness of 50μm (the recommended value is for reference only and can be set by the doctor in practice), the optical zone will be increased by 0.1mm in sequence, with a maximum of no more than 7.00mm, and the lens base will be increased by 5 microns in sequence until the expected corneal cutting thickness is greater than the recommended cutting thickness of 50 microns.

[0057] The pupil diameter of patient 1 to be operated on is relatively large, at 7.5mm, which is considered to exceed the pupil diameter setting value set by the doctor. The central thickness of the cornea is 550μm, and the refractive power is -6.00D (i.e. myopia of 600 degrees). The conventional setting of the optical zone diameter is 6.5mm, and the estimated corneal cutting thickness is 108μm. Since the patient has a relatively large pupil diameter, the optical zone is automatically enlarged by 0.1mm, PTA=108 / 550=19.6%. If PTA is less than 28%, the optical zone will continue to be enlarged to the maximum value of the optical zone, such as 7.00mm.

[0058] The pupil diameter of patient 2 to be operated on is relatively large, at 7.5mm, which is considered to exceed the pupil diameter setting value set by the doctor. The central corneal thickness is 520μm, the refractive power is -8.00D, the optical zone is conventionally set to 6.5mm, and the estimated corneal cutting thickness is 135μm. Due to the large pupil diameter of this patient, the optical zone is automatically enlarged by 0.1mm. When PTA is less than 28%, it is further enlarged by 0.1mm until the optical zone diameter is 6.8mm. At this time, PTA=148 / 520=28.46%. When PTA is greater than 28%, the optical zone is reduced by 0.1mm and the optical zone is set to 6.7mm, which is the optimal optical zone diameter.

[0059] The pupil diameter of patient 2 who was to undergo surgery was relatively large, at 7.5mm, which was considered to exceed the pupil diameter cutoff value set by the doctor. The central corneal thickness was 520 microns, the refractive power was -8.00D, the optical zone was conventionally set to 6.5mm, and the estimated corneal cutting thickness was 135μm. According to the maximum allowable corneal cutting thickness = central corneal thickness × 0.28 = 520μm × 0.28 = 145.6μm, the optical zone was gradually increased by 0.1mm until the estimated corneal cutting thickness was greater than 145.6μm. When the optical zone was 6.8mm, the estimated corneal cutting thickness was 148μm, which was greater than 145.6μm. At this time, the optical zone was reduced by 0.1mm, and the optimal optical zone diameter was designed to be 6.7mm. The corneal cap thickness is 120 μm, and the residual stromal bed thickness is 520-120-145=255 μm. At this time, the optical zone diameter needs to be reduced to a residual basal bed thickness greater than 280 μm. When the optical zone is 6.0 mm, the corneal ablation thickness is expected to be 115 μm, and the residual stromal bed thickness is 520-120-115=285 μm. At this time, the optical zone diameter is the optimal value. This indicates that this patient needs to explain the risk of postoperative glare.

[0060] The central corneal thickness of patient 3 to be operated on was 520μm, the refractive power was -2.00D, the conventional setting of the optical zone was 6.5mm, and the corneal thickness was expected to be cut to 43μm. At this time, the lens was too thin, and the diameter of the optical zone was increased to 7.0mm. At this time, the corneal thickness was expected to be cut to 45μm, which was still less than 50μm. The base thickness of the lens was increased by 5μm (the corneal thickness was expected to be cut). At this time, the base thickness of the lens was greater than or equal to 50μm, and the surgical design was completed. At this time, the base thickness of the lens and the diameter of the optical zone were the optimal parameters.

[0061] Patient 4 who was to undergo surgery had a smaller pupil diameter of 5.5 mm, a central corneal thickness of 520 μm, a refractive power of -8.00 D, a conventional optical zone setting of 6.5 mm, and a central thickness of the cutting lens of 135 μm. According to the maximum allowable corneal cutting thickness = central corneal thickness × 0.28 = 520 μm × 0.28 = 145.6 μm, the residual stromal bed thickness is 520-120-135 = 265 μm. At this time, the optical zone diameter needs to be reduced to a residual stromal bed thickness greater than 280 μm. When the optical zone is 6.0 mm, the lens thickness is 115 μm, and the residual stromal bed thickness is 520-120-115 = 285 μm. At this time, the optical zone diameter is the optimal value.

[0062] In an exemplary embodiment, a computer device is provided, including a memory and a processor, wherein a computer program is stored in the memory, and the processor implements the above-mentioned femtosecond laser refractive surgery parameter optimization method when executing the computer program.

[0063] In an exemplary embodiment, a computer-readable storage medium is provided, storing a computer program, which, when executed by a processor, implements the above-mentioned femtosecond laser refractive surgery parameter optimization method.

[0064] In an exemplary embodiment, a computer program product is provided, comprising a computer program, which implements the above-mentioned femtosecond laser refractive surgery parameter optimization method when executed by a processor.

[0065] Those skilled in the art can understand that all or part of the processes in the above-mentioned embodiment methods can be completed by instructing the relevant hardware through a computer program, and the computer program can be stored in a non-volatile computer-readable storage medium. When the computer program is executed, it can include the processes of the embodiments of the above-mentioned methods. Among them, any reference to the memory, database or other medium used in the embodiments provided in the present application can include at least one of non-volatile and volatile memory. Non-volatile memory can include read-only memory (ROM), magnetic tape, floppy disk, flash memory, optical memory, high-density embedded non-volatile memory, resistive random access memory (ReRAM), magnetic random access memory (MRAM), ferroelectric random access memory (FRAM), phase change memory (PCM), graphene memory, etc. Volatile memory can include random access memory (RAM) or external cache memory, etc. By way of illustration and not limitation, RAM may be in various forms, such as static random access memory (SRAM) or dynamic random access memory (DRAM).

[0066] The database involved in each embodiment provided in this application may include at least one of a relational database and a non-relational database. The non-relational database may include a distributed database based on blockchain, etc., but is not limited thereto. The processor involved in each embodiment provided in this application may be a general-purpose processor, a central processing unit, a graphics processor, a digital signal processor, a programmable logic device, a data processing logic device based on quantum computing, etc., but is not limited thereto.

[0067] The technical features of the above embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0068] This article uses specific examples to illustrate the principles and implementation methods of this application. The description of the above embodiments is only used to help understand the method and core ideas of this application. At the same time, for those skilled in the art, according to the ideas of this application, there will be changes in the specific implementation methods and application scope. In summary, the content of this specification should not be understood as limiting this application.

Claims

1. A femtosecond laser refractive surgery parameter optimization method, characterized in that: include: Obtain the patient's pupil diameter; Determine whether the pupil diameter is greater than a pupil diameter setting value, and obtain a first determination result; If the first judgment result is yes, adjusting the optical zone according to the expected corneal ablation thickness and the residual stromal bed thickness; If the first judgment result is no, the optical zone is adjusted according to the expected corneal ablation thickness.

2. The femtosecond laser refractive surgery parameter optimization method according to claim 1, characterized in that: Adjust the optical zone based on the expected corneal ablation thickness and residual stromal bed thickness, including: Increase the optical area; Determine the corneal estimated ablation thickness and the residual stromal bed thickness according to the current optical zone diameter; the corneal estimated ablation thickness is determined according to the optical zone diameter and the diopter; the residual stromal bed thickness is determined according to the corneal central thickness, the corneal estimated ablation thickness and the corneal cap; Determine whether the residual stromal bed thickness is less than a set thickness or whether the ratio of the estimated corneal ablation thickness to the corneal central thickness is greater than a set ratio, and obtain a second determination result; If the second judgment result is yes, the current optical zone diameter is adjusted down by a preset adjustment amount, and the method returns to "determine the estimated corneal ablation thickness and the residual stromal bed thickness according to the current optical zone diameter".

3. The femtosecond laser refractive surgery parameter optimization method according to claim 2, characterized in that: The optical zone diameter is less than or equal to the optical zone set diameter.

4. The femtosecond laser refractive surgery parameter optimization method according to claim 3, characterized in that: Adjust the optical zone according to the expected corneal ablation thickness, including: Determining whether the estimated corneal ablation thickness is greater than the maximum allowable corneal ablation thickness; the estimated corneal ablation thickness is determined based on the optical zone diameter and the diopter; If yes, the current optical zone diameter is reduced by a preset adjustment amount, and the process returns to "determining whether the estimated corneal cutting thickness is greater than the maximum allowable corneal cutting thickness"; If not, the current optical zone diameter is not adjusted.

5. The femtosecond laser refractive surgery parameter optimization method according to claim 4, characterized in that: Also includes: Determine whether the estimated corneal cutting thickness is less than the recommended cutting thickness value to obtain a third determination result; If the third judgment result is yes, the current optical zone diameter is increased by a preset adjustment amount, and it is determined whether the current optical zone diameter is equal to the optical zone set diameter, to obtain a fourth judgment result; If the fourth judgment result is yes, the lens base is increased by the set value, and the process returns to "determine whether the corneal estimated cutting thickness is less than the cutting thickness recommended value"; if the fourth judgment result is no, the process returns directly to "determine whether the corneal estimated cutting thickness is less than the cutting thickness recommended value"; If the third judgment result is no, the current optical zone diameter is not adjusted.

6. The femtosecond laser refractive surgery parameter optimization method according to claim 1, characterized in that: Maximum allowable corneal ablation thickness = central corneal thickness × set ratio.

7. A computer device comprising: A memory, a processor, and a computer program stored in the memory and executable on the processor, wherein the processor executes the computer program to implement the femtosecond laser refractive surgery parameter optimization method according to any one of claims 1 to 6.

8. A computer-readable storage medium having a computer program stored thereon, characterized in that: When the computer program is executed by a processor, the femtosecond laser refractive surgery parameter optimization method described in any one of claims 1 to 6 is implemented.

9. A computer program product, comprising a computer program, characterized in that When the computer program is executed by a processor, the femtosecond laser refractive surgery parameter optimization method described in any one of claims 1 to 6 is implemented.

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