Ginsenoside mixture preparation equipment and preparation method

Abstract

The invention relates to the field of ginsenoside mixture preparation, in particular to ginsenoside mixture preparation equipment and a ginsenoside mixture preparation method. The ginsenoside mixture preparation equipment is mainly composed of a mixing tank and a heater, two times of clear liquid filtration treatment are completed through cooperation of a main scraper blade and a flow dividing assembly and precipitation scraping and suction on the two sides of a filtrate piece, and the treatment time consumed by mutual transfer of raw materials in different treatment tank bodies is saved. According to the preparation method of the ginsenoside mixture, the ginsenoside mixture preparation equipment is used, a unique preparation process combining a fermentation method and a chemical method is adopted, and meanwhile, a membrane process is combined, so that a process for preparing a mixture with high content of Rg3 and Rh2 is developed; the problems that a product has bad smell and rare ginsenoside CK cannot be generated due to addition of exogenous acid in a chemical method are avoided, and the problems that a fermentation method is low in yield and the composition of the rare ginsenoside in the product is not rich enough are solved.

Description

Technical Field

[0001] The present invention relates to the field of preparation of ginsenoside mixture, and in particular to a preparation device and a preparation method of ginsenoside mixture. Background Art

[0002] Ginsenosides are the main active ingredients of Panax plants of the Araliaceae family (ginseng, American ginseng, Panax notoginseng, etc.), and are widely distributed in the roots, stems, leaves, flowers and fruits of Panax plants. They have multiple pharmacological effects such as enhancing immunity, regulating the central nervous system, protecting the cardiovascular and cerebrovascular systems, and resisting fatigue. Common ginsenosides refer to ginsenosides with higher content in Panax plants. Rare ginsenosides are a special type of ginsenosides formed by hydrolysis of the sugar groups of protopanaxadiol and protopanaxtriol ginsenosides or changes in the side chains of the parent nucleus. This type of ginsenoside is found in relatively low content in Panax plants, so it is called rare ginsenosides and is difficult to obtain through traditional extraction and separation methods (such as ginsenoside 20(R / S)-Rg3, 20(R / S)-Rh2, Rk1, Rg5, Rk2, Rh3, Rg6, Rk3, Rh4, CK, etc.).

[0003] At present, the preparation methods of rare ginsenosides include physical conversion method, chemical conversion method and fermentation method. The physical conversion method generally refers to high-temperature steaming of the raw materials, and then obtaining rare ginsenosides by utilizing the property that the sugar group at the C-20 position of the ginsenoside is easily decomposed by heat. When converting rare ginsenosides by this method, there is a problem of too low conversion rate; the chemical method generally refers to adding exogenous acid or alkali, and acidolysis under heating conditions to produce rare ginsenosides. This method requires the addition of exogenous acid or alkali to convert rare ginsenosides, resulting in the product having the odor of the added acid or alkali, and it cannot be removed during the production process. At the same time, this method cannot produce rare ginsenosides such as CK that require specific acidolysis; the fermentation method generally refers to adding specific enzymes to specifically cut the sugar group of ordinary ginsenosides, so as to achieve the purpose of converting rare ginsenosides. However, when converting rare ginsenosides, this method often has problems such as low yield, insufficient composition of rare ginsenosides in the product, and its production scale cannot be compared with the chemical method. Summary of the invention

[0004] In order to overcome the problem that the addition of exogenous acid by the chemical method in the preparation method of rare ginsenosides causes the product to have a bad smell and cannot produce rare ginsenoside CK, and solve the shortcomings of low yield of the fermentation method and insufficient composition of rare ginsenosides in the product, the present invention provides a ginsenoside mixture preparation device and preparation method.

[0005] Technical solution: A ginsenoside mixture preparation device, comprising a fixed frame, a mixing tank, a top cover, a heater, a conical frame, a sealing piece, a filtrate piece, a baffle, a diversion assembly, a fixed column, a rotating shaft, a sleeve, a swivel, a lifting electric push rod, a motor, a stirring blade and a main scraper; the fixed frame is sequentially mounted with a mixing tank and a heater for heating the mixing tank; the upper cover of the mixing tank is provided with a top cover; a conical frame is fixedly connected in the mixing tank; a filtrate piece is fixedly connected to the conical frame; a baffle is rotatably connected to the conical frame, and the baffle is located below the filtrate piece and the baffle; a plurality of mesh structures are opened on the baffle; a sealing piece is fixedly connected to the conical frame ... The plug is tightly attached to the mesh structure of the baffle; a diversion component is commonly connected between the baffle and the heater; a fixed column is fixedly connected to the baffle; a rotating shaft is rotatably connected to the fixed column; a motor is installed on the top cover; the output shaft of the motor is plugged into the rotating shaft through a spline groove structure; a sleeve is slidably connected to the rotating shaft through a spline groove structure; a swivel is rotatably connected to the sleeve; a lifting electric push rod is installed on the top cover; the telescopic end of the lifting electric push rod is fixedly connected to the swivel through a movable buckle structure; a number of stirring blades are fixedly connected to the sleeve; a main scraper is fixedly connected to the stirring blade; a number of plug rods are fixedly connected to the sleeve; and an insert tube corresponding to the number and position of the plug rods is fixedly connected to the fixed column.

[0006] Furthermore, an electric control valve is installed on the top cover.

[0007] Furthermore, the baffle is provided with groove structures corresponding to the number and position of the sealing pieces; all mesh structures of the baffle are respectively located in each groove structure; and the sealing pieces are plugged into the corresponding groove structures on the baffle.

[0008] Furthermore, the diversion component includes a liquid collecting bucket, a guide pipe, a confluence pipe and an electrically controlled three-way valve; a plurality of liquid collecting buckets are fixedly connected to the baffle plate; all mesh structures on the baffle plate are connected to each liquid collecting bucket; the liquid outlet structure of the liquid collecting bucket is connected to the guide pipe; the electrically controlled three-way valve is fixedly connected to the heater; the confluence pipe is rotatably connected to the electrically controlled three-way valve, and the upper liquid inlet structure of the electrically controlled three-way valve is connected to the confluence pipe; and the four guide pipes are connected to the confluence pipe together.

[0009] Furthermore, an electric suction machine is installed on the upper liquid inlet structure of the electric-controlled three-way valve.

[0010] Furthermore, a flow velocity sensor is installed on the flow guide pipe.

[0011] Furthermore, the main scraper is fixedly connected with a brush.

[0012] Furthermore, a movable plate is slidably connected in the liquid collecting bucket; a filtrate net is fixedly connected to the movable plate; a micro electric push rod is fixedly connected in the liquid collecting bucket; an auxiliary scraper is fixedly connected to the telescopic end of the micro electric push rod; and a tension spring is fixedly connected between the auxiliary scraper and the adjacent movable plate.

[0013] A method for preparing a ginsenoside mixture comprises the following steps: Step 1, crushing and sieving, crushing the mixture of three solid raw materials of ginseng stems and leaves, American ginseng stems and leaves, and Panax notoginseng stems and leaves, and passing through a 60-mesh sieve; Step 2, mixing the raw materials for the first time, pouring the three solid raw materials of ginseng stems and leaves, American ginseng stems and leaves, and Panax notoginseng stems and leaves after crushing and sieving, the solid raw materials of lactic acid bacteria and the single liquid raw material of water into a mixing tank, fermenting at 25°C-45°C for 24h, and mixing the raw materials; Step 3, the first clear liquid filtration, the clear liquid in the raw material is filtered through the filtrate sheet and discharged and discarded, leaving only the precipitate of the raw material in the mixing tank; Step 4: Mix the raw materials for the second time, pour 40%-60% ethanol into the mixing tank where the raw material precipitation is retained, stir and extract at 60℃-70℃ for 90min-150min, and mix the raw materials; Step 5: Second clear liquid filtration: the clear liquid in the raw material is filtered through a filtrate sheet and discharged and collected, leaving only the precipitate of the raw material in the mixing tank; Step 6: Ultrafiltration treatment: the collected raw material clear liquid is transferred to an ultrafiltration device, and the raw material clear liquid is passed through a ceramic membrane and an ultrafiltration membrane in the ultrafiltration device to complete the ultrafiltration treatment, thereby obtaining an ultrafiltration permeate; Step 7, concentration treatment, transferring the ultrafiltration permeate to a spherical concentrator and concentrating it to an alcohol-free state, and then allowing the concentrate to stand and separate into a clear liquid and a precipitate; Step 8, filtering the clear liquid for the third time, filtering the clear liquid obtained by layering the concentrated liquid and discharging and discarding it, taking and collecting the precipitate obtained after filtering; Step nine, drying and crushing, transferring the collected precipitate to a vacuum drying oven for drying, and then crushing and sieving to obtain a ginsenoside extract with a Rg3 content of more than 40% and a Rh2 content of more than 30%, and the ginsenoside product contains a rare saponin mixed extract of CK.

[0014] Furthermore, in step 2, the ratio of the mixture of ginseng stems and leaves, American ginseng stems and leaves, and Panax notoginseng stems and leaves is 1:4:8; the ratio of water to the mixture of ginseng stems and leaves, American ginseng stems and leaves, and Panax notoginseng stems and leaves is 1:5-10.

[0015] Furthermore, in step 4, the ratio of ethanol to the mixture of ginseng stems and leaves, American ginseng stems and leaves, and Panax notoginseng stems and leaves is 1:5-20.

[0016] The beneficial effects are as follows: a ginsenoside mixture preparation device of the present invention is mainly composed of a mixing tank and a heater, the raw materials in the mixing tank are stirred and mixed by a stirring blade, a filtrate sheet is arranged in the mixing tank through a conical frame, and two clear liquid filtration treatments are completed by a main scraper in cooperation with a diversion component, and precipitation scraping and suction are respectively performed on both sides of the filtrate sheet, thereby eliminating the processing time consumed by the mutual transfer of raw materials in different processing tanks; a ginsenoside mixture preparation method of the present invention uses the above-mentioned ginsenoside mixture preparation device, a unique preparation process combining fermentation and chemical methods, and a membrane process is combined to develop a process for preparing a high-content Rg3 and Rh2 mixture, that is, the problem of the product having a bad odor and being unable to produce the rare ginsenoside CK due to the addition of exogenous acid in the chemical method is avoided, and the problem of low yield of the fermentation method and insufficient composition of rare ginsenosides in the product is solved. The method used is simple, flexible and convenient, and can be prepared in large quantities while saving time. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 A schematic diagram for describing the present invention according to an embodiment; Figure 2 A cross-sectional view of a mixing tank is provided to describe the present invention according to an embodiment; Figure 3 A schematic diagram of a conical frame and a baffle is described according to an embodiment of the present invention; Figure 4 A schematic diagram of a fixed column and a rotating shaft is described according to an embodiment of the present invention; Figure 5 An exploded view of a conical frame and a baffle of the present invention is described according to an embodiment; Figure 6 A schematic diagram of a baffle for describing the present invention according to an embodiment; Figure 7 A schematic diagram of a liquid collecting hopper and a flow guide pipe according to an embodiment of the present invention is described; Figure 8 A cross-sectional view of a liquid collecting bucket according to an embodiment of the present invention is described; Fig. 9 The figure is a schematic diagram of a moving plate and a filtrate network according to an embodiment of the present invention.

[0018] Figure numbers: 1-fixed frame, 11-mixing tank, 12-top cover, 121-electrically controlled valve, 13-heater, 21-conical skeleton, 211-sealing plate, 22-filtrate plate, 23-baffle, 2301-mesh structure, 2302-groove structure, 24-liquid collecting bucket, 2401-liquid outlet hole structure, 25-flow guide pipe, 26-manifold, 27-electrically controlled three-way valve, 28-electric suction machine, 29-flow rate sensor, 31-fixed column, 311-insert cylinder, 32-rotating shaft, 33-sleeve, 34-insert rod, 35-swivel, 36-lifting electric push rod, 37-motor, 41-stirring blade, 42-main scraper, 43-brush, 51-moving plate, 52-filtrate net, 53-micro electric push rod, 54-auxiliary scraper, 55-tension spring. DETAILED DESCRIPTION

[0019] The technical solution of the present invention is further described below in conjunction with the accompanying drawings.

[0020] Example 1 A ginsenoside mixture preparation device, such as Figure 1-Figure 9As shown, it includes a fixing frame 1, a mixing tank 11, a top cover 12, a heater 13, a conical frame 21, a sealing sheet 211, a filtrate sheet 22, a baffle 23, a diversion assembly, a fixing column 31, a rotating shaft 32, a sleeve 33, a plug 34, a swivel 35, a lifting electric push rod 36, a motor 37, a stirring blade 41 and a main scraper 42; the fixing frame 1 is sequentially mounted with a mixing tank 11 and a heater 13 for heating the mixing tank 11; the mixing tank 11 is covered with a top cover 12; the mixing tank A conical frame 21 is fixedly connected to the bottom of the inner part of the heater 11; a filtrate sheet 22 is fixedly connected to the conical frame 21; a baffle 23 is rotatably connected to the conical frame 21, and the baffle 23 is located below the filtrate sheet 22 and the baffle 23; a plurality of mesh structures 2301 are respectively provided in four directions of the baffle 23; four sealing sheets 211 are fixedly connected to the conical frame 21; the four sealing sheets 211 are initially closely attached to the mesh structures 2301 in four directions of the baffle 23; a diversion group is commonly connected between the baffle 23 and the heater 13 The baffle 23 is fixed with a fixed column 31; the fixed column 31 is rotatably connected with a rotating shaft 32; a motor 37 is installed on the top cover 12; the output shaft of the motor 37 is plugged into the rotating shaft 32 through a spline groove structure; a sleeve 33 is slidably connected to the rotating shaft 32 through a spline groove structure; a swivel 35 is rotatably connected to the sleeve 33; a lifting electric push rod 36 is installed on the top cover 12; the telescopic end of the lifting electric push rod 36 is fixedly connected to the swivel 35 through a movable buckle structure, and during the process of disassembling and assembling the top cover 12, the lifting electric push rod 36 is fixedly connected to the swivel 35 through a movable buckle structure. By directly pulling the top cover 12 and the lifting electric push rod 36 upward, the telescopic end of the lifting electric push rod 36 can be pulled out from the rotating ring 35 through the movable buckle structure; four stirring blades 41 are fixedly connected to the sleeve 33; each of the four stirring blades 41 is fixedly connected to a main scraper 42; a plurality of plug rods 34 are fixedly connected to the sleeve 33; plug cylinders 311 corresponding to the number and position of the plug rods 34 are fixedly connected to the fixed column 31; an electric control valve 121 is installed on the top cover 12; the electric control valve 121 is externally connected to an ethanol delivery device.

[0021] like Figure 5 and Figure 6 As shown, the baffle plate 23 is provided with groove structures 2302 corresponding to the number and position of the sealing pieces 211; all mesh structures 2301 of the baffle plate 23 are respectively located in each groove structure 2302; and the four sealing pieces 211 are initially plugged into the corresponding groove structures 2302 on the baffle plate 23.

[0022] like Figure 1-Figure 5 and Figure 7As shown, the flow dividing assembly includes a liquid collecting bucket 24, a flow guide tube 25, a flow conduit 26, an electric three-way valve 27, an electric suction machine 28 and a flow rate sensor 29; four liquid collecting buckets 24 are fixedly connected to the baffle 23; all mesh structures 2301 on the baffle 23 are respectively connected to each liquid collecting bucket 24; each of the liquid outlet hole structures 2401 of the four liquid collecting buckets 24 is connected to a flow guide tube 25; the heater 13 is fixedly connected to the electric three-way valve 2 7. The electric-controlled three-way valve 27 is provided with an upper liquid inlet structure, a left liquid outlet structure and a right liquid outlet structure; a manifold 26 is rotatably connected to the electric-controlled three-way valve 27, and the upper liquid inlet structure of the electric-controlled three-way valve 27 is connected to the manifold 26; four guide pipes 25 are connected to the manifold 26 together; an electric suction machine 28 is installed on the upper liquid inlet structure of the electric-controlled three-way valve 27; and a flow rate sensor 29 is installed on each of the four guide pipes 25.

[0023] The left liquid outlet structure of the electric-controlled three-way valve 27 is externally connected to a waste liquid recovery device, and the right liquid outlet structure of the electric-controlled three-way valve 27 is externally connected to an ultrafiltration device.

[0024] The following is a ginsenoside mixture preparation device of the present invention, and the first raw material mixing and first clear liquid filtering working steps in the ginsenoside mixture preparation work.

[0025] First, the staff opens the top cover 12, puts the three mixed solid raw materials of ginseng stems and leaves, American ginseng stems and leaves, and Panax notoginseng stems and leaves and the lactic acid bacteria solid raw material and water into the mixing tank 11, and then puts the top cover 12 back on the mixing tank 11. At this time, the electric three-way valve 27 is in a closed state. Then, the raw materials in the mixing tank 11 are heated by the heater 13, and at the same time, the output shaft of the motor 37 drives the rotating shaft 32 to rotate, and the rotating shaft 32 drives the various stirring blades 41 on the sleeve 33 to rotate in the mixing tank 11 to stir the raw materials, completing the first raw material mixing process. After the heating and stirring are completed, the motor 37 stops driving the stirring blades 41 to rotate, and the heater 13 stops heating.

[0026] Afterwards, the electrically controlled three-way valve 27 automatically switches to a state where the upper liquid inlet structure and the left liquid outlet structure are connected to each other. At the same time, the lifting electric push rod 36 pushes the rotating ring 35 to drive the sleeve 33 and the stirring blade 41 and the main scraper 42 connected thereto to move downward until the main scraper 42 is close to the upper surface of the filtrate sheet 22. At the same time, the insertion rod 34 on the sleeve 33 is inserted downward into the insertion tube 311 of the fixed column 31, so that the fixed column 31 and the sleeve 33 form a whole. Subsequently, the output shaft of the motor 37 drives the rotating shaft 32 and the stirring blade 41 and the main scraper 42 connected to the sleeve 33 to rotate slowly. The sleeve 33 also drives the fixed column 31 and the baffle 23 connected thereto to rotate. When the groove structure 2302 of the baffle 23 leaves the sealing piece 211 of the conical skeleton 21, the clean water obtained by stratification in the mixing tank 11 is The liquid will successively flow downward through the filter liquid sheet 22, the mesh structure 2301 of the baffle 23, the liquid collecting bucket 24, the guide pipe 25, the conduit 26 and the electric-controlled three-way valve 27, and be discharged outwardly from the left liquid outlet structure of the electric-controlled three-way valve 27 to the external waste liquid recovery device. At the same time, the main scraper 42 continuously scrapes away the sediment deposited on the surface of the filter liquid sheet 22, so that the clear liquid is not blocked by the sediment and flows downward to the filter liquid sheet 22. The electric suction machine 28 performs suction work on the upper liquid inlet structure of the electric-controlled three-way valve 27, so that the liquid collecting bucket 24 sucks the clear liquid below the area where the filter liquid sheet 22 is scraped by the main scraper 42, and then the clear liquid in the mixing tank 11 can flow downward through the filter liquid sheet 22 faster under the suction action, thereby improving the filtering treatment efficiency of the clear liquid and completing the first clear liquid filtration work.

[0027] The following is a ginsenoside mixture preparation device of the present invention, and the second raw material mixing and second clear liquid filtering steps in the ginsenoside mixture preparation work.

[0028] When the flow rate sensor 29 recognizes that no clear liquid flows through the guide tube 25, it indicates that the first clear liquid filtering work has been completed, and only sediment exists in the mixing tank 11. Thereafter, the electrically controlled three-way valve 27 automatically switches to a closed state, and the electrically controlled valve 121 automatically controls the external ethanol delivery equipment to automatically deliver ethanol single liquid raw material to the mixing tank 11. After the electrically controlled valve 121 closes the ethanol delivery work, the heater 13 heats the raw material in the mixing tank 11, and at the same time, the output shaft of the motor 37 drives the stirring blade 41 to rotate in the mixing tank 11 to stir the raw material, completing the second raw material mixing process. After the heating and stirring are completed, the motor 37 stops driving the stirring blade 41 to rotate, and the heater 13 stops heating.

[0029] Afterwards, the electrically controlled three-way valve 27 automatically switches to a state where the upper liquid inlet structure and the right liquid outlet structure are connected to each other, and according to the above steps, the clear liquid in the mixing tank 11 is automatically sucked to flow through the liquid collecting bucket 24, the guide pipe 25, the conduit 26 and the electrically controlled three-way valve 27, and is discharged outwardly from the right liquid outlet structure of the electrically controlled three-way valve 27 to the external ultrafiltration equipment for the next processing step, completing the second clear liquid filtration work.

[0030] The ginsenoside mixture preparation equipment of the present invention can automatically complete two raw material mixing and filtering processing tasks in succession by relying on a single device during the entire ginsenoside mixture preparation work, without the need for manual long-term waiting for the transfer of raw materials after the completion of each step, thereby reducing the alternating use of multiple mixing and filtering equipment, and automatically completing the mixing and filtering processing tasks to improve the ginsenoside mixture preparation efficiency, and the overall steps of the equipment are simple to operate.

[0031] A method for preparing a ginsenoside mixture comprises the following steps: Step 1, crushing and sieving, crushing the mixture of three solid raw materials of ginseng stems and leaves, American ginseng stems and leaves, and Panax notoginseng stems and leaves, and passing through a 60-mesh sieve; Step 2, mixing the raw materials for the first time, pouring the three solid raw materials of ginseng stems and leaves, American ginseng stems and leaves, and Panax notoginseng stems and leaves after crushing and sieving, the solid raw material of lactic acid bacteria and the single liquid raw material of water into a mixing tank 11, fermenting at 25° C. for 24 hours, and mixing the raw materials; Step 3, the first clear liquid filtration, the clear liquid in the raw material is filtered through the filtrate sheet 22 and discharged and discarded, leaving only the precipitate of the raw material in the mixing tank 11; Step 4, mixing the raw materials for the second time, pouring 50% ethanol into the mixing tank 11 where the raw material precipitation is retained, stirring and extracting at 50° C. for 120 minutes, and mixing the raw materials; Step 5, filtering the clear liquid for the second time, filtering the clear liquid in the raw material through the filtrate sheet 22 and discharging and collecting it, leaving only the precipitate of the raw material in the mixing tank 11; Step 6: Ultrafiltration treatment: the collected raw material clear liquid is transferred to an ultrafiltration device, and the raw material clear liquid is passed through a ceramic membrane and an ultrafiltration membrane in the ultrafiltration device to complete the ultrafiltration treatment, thereby obtaining an ultrafiltration permeate; Step 7, concentration treatment, transferring the ultrafiltration permeate to a spherical concentrator and concentrating it to an alcohol-free state, and then allowing the concentrate to stand and separate into a clear liquid and a precipitate; Step 8, filtering the clear liquid for the third time, filtering the clear liquid obtained by layering the concentrated liquid and discharging and discarding it, taking and collecting the precipitate obtained after filtering; Step nine, drying and crushing, transferring the collected precipitate to a vacuum drying oven for drying, and then crushing and sieving to obtain a ginsenoside extract with a Rg3 content of more than 40% and a Rh2 content of more than 30%, and the ginsenoside product contains a rare saponin mixed extract of CK.

[0032] In step 2, the ratio of the mixture of ginseng stems and leaves, American ginseng stems and leaves, and Panax notoginseng stems and leaves is 1:4:4; the ratio of water to the mixture of ginseng stems and leaves, American ginseng stems and leaves, and Panax notoginseng stems and leaves is 1:5; in step 4, the ratio of ethanol to the mixture of ginseng stems and leaves, American ginseng stems and leaves, and Panax notoginseng stems and leaves is 1:5.

[0033] Example 2 Based on the first embodiment, a brush 43 is fixedly connected to the bottom of each of the four main scrapers 42 of this embodiment.

[0034] When the raw materials in the mixing tank 11 are stirred and mixed by the stirring blade 41, the lifting electric push rod 36 pushes the rotating ring 35 to drive the sleeve 33 and the stirring blade 41, the main scraper 42 and the brush 43 connected thereto to move downward, so that the brush 43 is in close contact with the outer surface of the filtrate sheet 22, and the brush 43 is in a state of being in close contact with the outer surface of the filtrate sheet 22 and continuously rotating with the stirring blade 41. The solid raw materials accumulated on the outer surface of the filtrate sheet 22 are continuously brushed by the brush 43 to make them float upward in the liquid raw materials, thereby increasing the mixing speed of the solid raw materials and the liquid raw materials and improving the stirring and mixing efficiency of the raw materials.

[0035] Example 3 On the basis of Example 1, each of the four liquid collecting buckets 24 of this embodiment is slidably connected to a movable plate 51; each of the four movable plates 51 is fixedly connected to a filtrate net 52 that initially covers the liquid outlet hole structure 2401 on the liquid collecting bucket 24; each of the four liquid collecting buckets 24 is fixedly connected to a micro electric push rod 53; each of the telescopic ends of the four micro electric push rods 53 is fixedly connected to an auxiliary scraper 54, and the telescopic ends of the micro electric push rods 53 pass through the adjacent movable plates 51; each of the four auxiliary scrapers 54 and the adjacent movable plates 51 is fixedly connected to a tension spring 55.

[0036] In the process of filtering and extracting the clear liquid in the mixing tank 11 outward, the micro-electric push rod 53 first pulls the auxiliary scraper 54 to drive the tension spring 55 and the movable plate 51 connected thereto to move in the direction of the liquid outlet structure 2401 away from the liquid collecting bucket 24, so that the liquid outlet structure 2401 of the liquid collecting bucket 24 is not covered. Thereafter, the main scraper 42 continuously scrapes along the surface of the filtrate sheet 22, so that the clear liquid can pass through the precipitate accumulated on the surface of the filtrate sheet 22 and flow out slowly and smoothly. When the main scraper 42 scrapes the filtrate sheet 22 during the second clear liquid filtration step, part of the clear liquid and precipitate will instantly pass through the damaged part of the filtrate sheet 22, successively pass through the mesh structure 2301 of the baffle 23 and the liquid outlet structure 2401 of the liquid collecting bucket 24, and flow through the flow velocity sensor 29 on the guide tube 25. At this time, the flow velocity sensor 29 will recognize that the clear liquid mixed with a small amount of precipitate flows through the guide tube 25. The flow rate of the flow tube 25 increases, and the flow rate sensor 29 immediately notifies the four micro-electric push rods 53 to start working through the circuit system. The micro-electric push rod 53 first pushes the auxiliary scraper 54 to drive the tension spring 55 and the movable plate 51 connected thereto to reset and move, and the filtrate net 52 on the movable plate 51 covers the liquid outlet structure 2401 of the collecting bucket 24 again, so that the subsequent clear liquid flowing to the collecting bucket 24 needs to pass through the filtrate net 52 to flow through the liquid outlet structure 2401 and flow to the flow guide tube 25. At this time, the sediment carried by the clear liquid will continue to accumulate on the filtrate net 52, and then the micro-electric push rod 53 drives the auxiliary scraper 54 to move back and forth along the surface of the filtrate net 52, and the auxiliary scraper 54 reciprocates to push away the sediment accumulated on the surface of the filtrate net 52, so that this batch of clear liquid can smoothly pass through the sediment accumulated on the surface of the filtrate net 52 to complete the filtration process, thereby avoiding the waste of clear liquid.

[0037] Although the filtered clear liquid carries a small amount of precipitate, the clear liquid can filter out the small amount of precipitate in the subsequent step of passing through the ultrafiltration equipment. Finally, after the staff finishes the filtration of this batch of clear liquid, they need to replace the filtrate sheet 22 and all the filtrate nets 52 to proceed with the processing of the next batch of raw materials.

[0038] Example 4 The difference between this embodiment and embodiment 1 is that in step 2, the ratio of the mixture of ginseng stems and leaves, American ginseng stems and leaves and Panax notoginseng stems and leaves is 1:4:8; the ratio of water to the mixture of ginseng stems and leaves, American ginseng stems and leaves and Panax notoginseng stems and leaves is 1:10; and the ratio of ethanol to the mixture of ginseng stems and leaves, American ginseng stems and leaves and Panax notoginseng stems and leaves in step 4 is 1:20.

[0039] Example 5 The difference between this embodiment and embodiment 1 is that, in step 2, the first raw material mixing, the three solid raw materials of ginseng stems and leaves, American ginseng stems and leaves, and Panax notoginseng stems and leaves that have been crushed and sieved, the solid raw materials of lactic acid bacteria and the single liquid raw material of water are poured into a mixing tank 11, fermented at 30°C for 24h, the raw materials are mixed, and the mixed raw materials are then allowed to stand and separate into clear liquid and precipitate.

[0040] Example 6 The difference between this embodiment and embodiment 1 is that, in step 4, the second raw material mixing is performed by pouring 40% ethanol into the mixing tank 11 retaining the raw material precipitate, stirring and extracting at 70° C. for 150 minutes, mixing the raw materials, and then allowing the mixed raw materials to stand and separate into a clear liquid and a precipitate.

[0041] While the present invention has been described with reference to exemplary embodiments, it is to be understood that the invention is not limited to the disclosed exemplary embodiments.The scope of the following claims is to be accorded the broadest interpretation so as to encompass all such modifications and equivalent structures and functions.

Claims

1. A ginsenoside mixture preparation device, comprising: a fixed frame (1); a mixing tank (11) and a heater (13) for heating the mixing tank (11) are sequentially mounted on the fixed frame (1); a top cover (12) is provided on the upper cover of the mixing tank (11); Its characteristics are: The mixing tank (11) further comprises a conical frame (21); the conical frame (21) is fixedly connected inside the mixing tank (11); a filtrate sheet (22) is fixedly connected to the conical frame (21); a baffle (23) is rotatably connected to the conical frame (21), and the baffle (23) is located below the filtrate sheet (22); a plurality of mesh structures (2301) are provided on the baffle (23); a sealing sheet (211) is fixedly connected to the conical frame (21); the sealing sheet (211) is closely attached to the mesh structure (2301) of the baffle (23); a flow dividing assembly is commonly connected between the baffle (23) and the heater (13); a fixing column (31) is fixedly connected to the baffle (23); a rotating shaft (32) is rotatably connected to the fixing column (31); a top cover ( A motor (37) is mounted on the top cover (12); the output shaft of the motor (37) is plugged into the rotating shaft (32) via a spline groove structure; a sleeve (33) is slidably connected to the rotating shaft (32) via the spline groove structure; a swivel (35) is rotatably connected to the sleeve (33); a lifting electric push rod (36) is mounted on the top cover (12); the telescopic end of the lifting electric push rod (36) is fixedly connected to the swivel (35) via a movable buckle structure; a plurality of stirring blades (41) are fixedly connected to the sleeve (33); a main scraper (42) is fixedly connected to the stirring blade (41); a plurality of plug rods (34) are fixedly connected to the sleeve (33); and a plug tube (311) corresponding in number and position to the plug rods (34) is fixedly connected to the fixed column (31).

2. The ginsenoside mixture preparation device according to claim 1, characterized in that: An electric control valve (121) is mounted on the top cover (12).

3. The ginsenoside mixture preparation device according to claim 1, characterized in that: The baffle plate (23) is provided with groove structures (2302) corresponding to the number and position of the sealing piece (211); all mesh structures (2301) of the baffle plate (23) are respectively located in each groove structure (2302); and the sealing piece (211) is plugged into the corresponding groove structure (2302) on the baffle plate (23).

4. The ginsenoside mixture preparation device according to claim 1, characterized in that: The flow diversion component comprises a liquid collecting hopper (24), a flow guide tube (25), a flow conduit (26) and an electrically controlled three-way valve (27); a plurality of liquid collecting hoppers (24) are fixedly connected to the baffle plate (23); all mesh structures (2301) on the baffle plate (23) are connected to the respective liquid collecting hoppers (24); the liquid outlet hole structure (2401) of the liquid collecting hopper (24) is connected to the flow guide tube (25); the electrically controlled three-way valve (27) is fixedly connected to the heater (13); the flow conduit (26) is rotatably connected to the electrically controlled three-way valve (27), and the upper liquid inlet structure of the electrically controlled three-way valve (27) is connected to the flow conduit (26); and the four flow guide tubes (25) are connected to the conduit (26) together.

5. The ginsenoside mixture preparation device according to claim 4, characterized in that: An electric suction machine (28) is installed on the upper liquid inlet structure of the electric-controlled three-way valve (27).

6. The ginsenoside mixture preparation device according to claim 4, characterized in that: A flow velocity sensor (29) is installed on the flow guide tube (25).

7. The ginsenoside mixture preparation device according to claim 1, characterized in that: The main scraper (42) is fixedly connected with a brush (43).

8. The ginsenoside mixture preparation device according to claim 1, characterized in that: A movable plate (51) is slidably connected in the liquid collecting bucket (24); a filtrate net (52) is fixedly connected to the movable plate (51); a micro electric push rod (53) is fixedly connected in the liquid collecting bucket (24); an auxiliary scraper (54) is fixedly connected to the telescopic end of the micro electric push rod (53); and a tension spring (55) is fixedly connected between the auxiliary scraper (54) and the adjacent movable plate (51).

9. A method for preparing a ginsenoside mixture, the method using a ginsenoside mixture preparation device according to any one of claims 1 to 8, characterized in that: The following steps are included: Step 1, crushing and sieving, crushing the mixture of three solid raw materials of ginseng stems and leaves, American ginseng stems and leaves, and Panax notoginseng stems and leaves, and passing through a 60-mesh sieve; Step 2, mixing the raw materials for the first time, pouring the three solid raw materials of ginseng stems and leaves, American ginseng stems and leaves, and Panax notoginseng stems and leaves after crushing and screening, the solid raw material of lactic acid bacteria and the single liquid raw material of water into a mixing tank (11), fermenting at 35° C. for 24 hours, and mixing the raw materials; Step 3, first clear liquid filtration, filtering the clear liquid in the raw material through the filtrate sheet (22) and discharging and discarding it, leaving only the precipitate of the raw material in the mixing tank (11); Step 4: Mix the raw materials for the second time. Pour 50% ethanol into the mixing tank (11) where the raw material precipitate is retained, stir and extract at 70°C for 100 minutes to mix the raw materials. Step 5, filtering the clear liquid for the second time, filtering the clear liquid in the raw material through the filtrate sheet (22) and discharging and collecting it, leaving only the precipitate of the raw material in the mixing tank (11); Step 6: Ultrafiltration treatment: the collected raw material clear liquid is transferred to an ultrafiltration device, and the raw material clear liquid is passed through a ceramic membrane and an ultrafiltration membrane in the ultrafiltration device to complete the ultrafiltration treatment, thereby obtaining an ultrafiltration permeate; Step 7, concentration treatment, transferring the ultrafiltration permeate to a spherical concentrator and concentrating it to an alcohol-free state, and then allowing the concentrate to stand and separate into a clear liquid and a precipitate; Step 8, filtering the clear liquid for the third time, filtering the clear liquid obtained by layering the concentrated liquid and discharging and discarding it, taking and collecting the precipitate obtained after filtering; Step nine, drying and crushing, transferring the collected precipitate to a vacuum drying oven for drying, and then crushing and sieving to obtain a ginsenoside extract with a Rg3 content of more than 40% and a Rh2 content of more than 30%, and the ginsenoside product contains a rare saponin mixed extract of CK.

10. The method for preparing a ginsenoside mixture according to claim 1, characterized in that: In step 2, the ratio of the mixture of ginseng stems and leaves, American ginseng stems and leaves, and Panax notoginseng stems and leaves is 1:4:6; the ratio of water to the mixture of ginseng stems and leaves, American ginseng stems and leaves, and Panax notoginseng stems and leaves is 1:8; in step 4, the ratio of ethanol to the mixture of ginseng stems and leaves, American ginseng stems and leaves, and Panax notoginseng stems and leaves is 1:10.

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