Colloidal gold method integrated detection tube
By designing a colloidal gold method integrated detection tube, the internal completion of sample dilution and antigen detection is achieved, the problems of cumbersome operation and safety hazards in the existing technology are solved, and the efficiency and safety of detection are improved.
Patent Information
- Application Number
- CN202310838888.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2023-07-10
- Publication Date
- 2025-01-10
AI Technical Summary
In colloidal gold antigen detection, the existing technology is cumbersome to operate, has a long identification time and is prone to infect humans due to improper operation, which poses safety hazards.
A colloidal gold method integrated detection tube is designed, integrating sample dilution and antigen detection. Through the thread assembly and sealing of the inner tube body, the internal completion of sample dilution and detection is achieved, and the sample is not directly contacted by the human body.
The detection process is simplified, the detection time is shortened, the human body harm caused by operational errors is reduced, and the safety and efficiency of detection is improved.
Smart Images

Figure CN119291180A_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the field of medical detection instruments, and in particular to a colloidal gold method integrated detection tube. Background Art
[0002] In clinical or laboratory colloidal gold antigen testing, samples are often collected from the nose, pharynx or mouth with a nasal swab or a throat swab, and then a sample diluent is added with a pipette or a dropper bottle. The sample is mixed and then the mixed sample solution is added dropwise to the test paper. This method is cumbersome, takes a long time to identify, and is prone to infecting the human body due to negligence or improper operation during the test process, causing harm to the human body. Summary of the invention
[0003] Therefore, in order to solve the above problems, the present invention provides a colloidal gold method integrated detection tube, which integrates sample dilution and antigen detection.
[0004] To achieve the above purpose, the technical solution provided by the present invention is as follows:
[0005] A colloidal gold method integrated detection tube, comprising:
[0006] An outer tube body, wherein at least one detection test strip is arranged inside the outer tube body;
[0007] An intermediate tube body, the intermediate tube body is inserted into the outer tube body, and the bottom of the intermediate tube body is provided with a raised central boss and a through hole located outside the central boss, and the through hole penetrates into the accommodating space of the outer tube body;
[0008] An inner tube body, wherein the inner tube body is inserted into the middle tube body, the bottom of the inner tube body forms a through bottom opening, the inner tube body and the middle tube body form a threaded assembly, and the center boss of the middle tube body is inserted into the bottom opening of the inner tube body to form a sealing fit;
[0009] The end cap is detachably mounted on the top opening of the inner tube body.
[0010] Furthermore, a test paper fixing frame is installed in the outer tube body, and the test paper fixing frame is located between the outer tube body and the middle tube body, and the test paper is fixed on the test paper fixing frame.
[0011] Furthermore, a plurality of test strips are arranged in the outer tube.
[0012] Furthermore, the outer tube body is a transparent tube body.
[0013] Furthermore, the intermediate tube body comprises a first tube section inserted into the outer tube body and a first tube head abutting against the tube opening of the outer tube body; the central boss and the through hole are arranged at the bottom of the first tube section.
[0014] Furthermore, the inner tube body includes a second tube section inserted into the first tube section and a second tube head protruding from the first tube head; the bottom opening is formed at the bottom of the second tube section, the second tube head includes a screw cap covering the outside of the first tube head and a third tube section protruding from the screw cap, the second tube section and the third tube section are connected, and the top opening is formed at the top of the third tube head.
[0015] Furthermore, the inner wall of the intermediate tube body is formed with internal threads, the bottom outer wall of the inner tube body is provided with external threads, and the inner tube body is threadedly connected by matching the external threads of the bottom outer wall with the internal threads of the inner wall of the intermediate tube body.
[0016] Furthermore, the inner wall of the intermediate tube body and the outer wall of the inner tube body are sealed together by a sealing ring.
[0017] Furthermore, the end cap is a nut, and the end cap is threadedly connected to the inner tube body and assembled on the top opening of the inner tube body.
[0018] Furthermore, the tightening direction of the end cap on the inner tube body is opposite to the tightening direction of the inner tube body on the intermediate tube body.
[0019] The technical solution provided by the present invention has the following beneficial effects:
[0020] In the solution of the present application, a diluent is stored in the inner tube body. After the sample is collected, the end cap is opened and the sample is immersed in the diluent in the inner tube body. After the dilution is completed, the inner tube body is rotated so that the bottom opening of the inner tube body is separated from the central boss. The diluted sample flows into the accommodation space of the outer tube body through the bottom opening and the through hole in sequence, thereby contacting the test paper to achieve antigen detection; the solution integrates sample dilution and antigen detection; the process is completed inside the test tube to avoid harm to the human body due to improper operation. BRIEF DESCRIPTION OF THE DRAWINGS
[0021] Figure 1 The figure shows the appearance of the colloidal gold method integrated detection tube in the embodiment;
[0022] Figure 2 The figure shows a cross-sectional view of the colloidal gold method integrated detection tube in the embodiment;
[0023] Figure 3 The figure shows a schematic diagram of the structure decomposition of the colloidal gold method integrated detection tube in the embodiment;
[0024] Figure 4 The figure shows a schematic diagram of the structure of the intermediate tube body in the embodiment;
[0025] Figure 5 The figure shows a schematic diagram of the structure of the inner tube body in the embodiment;
[0026] Figure 6 Shown is a cross-sectional view of the intermediate tube body in the embodiment. DETAILED DESCRIPTION
[0027] To further illustrate the various embodiments, the present invention provides drawings. These drawings are part of the disclosure of the present invention, which are mainly used to illustrate the embodiments and can be used in conjunction with the relevant descriptions in the specification to explain the operating principles of the embodiments. With reference to these contents, a person of ordinary skill in the art should be able to understand other possible implementations and advantages of the present invention. The components in the figures are not drawn to scale, and similar component symbols are generally used to represent similar components.
[0028] The present invention will now be further described with reference to the accompanying drawings and specific implementation methods.
[0029] Reference Figures 1 to 6 As shown, this embodiment provides a colloidal gold method integrated detection tube, including: an outer tube body 10, an intermediate tube body 30, an inner tube body 40 and an end cap 50; at least one detection test strip 21 is arranged in the outer tube body 10, preferably multiple, such as four detection test strips 21 in this specific embodiment; using multiple detection test strips 21, the same item can be detected at the same time to ensure accuracy, and multiple items can also be detected. Of course, in other embodiments, the number of detection test strips 21 can also be one, two, or more than two. The intermediate tube body 30 is inserted into the outer tube body 10, and the bottom of the intermediate tube body 30 is provided with a raised central boss 301 and a through hole 302 located on the periphery of the central boss 301, and the through hole 302 is connected to the accommodating space 101 of the outer tube body 10 (i.e., the space for accommodating the detection test strip 21).
[0030] The inner tube body 40 is inserted into the middle tube body 30, and a through bottom opening 401 is formed at the bottom of the inner tube body 40. The inner tube body 40 and the middle tube body 30 are threadedly assembled, and the central boss 301 of the middle tube body 30 is inserted into the bottom opening 401 of the inner tube body 40 to form a sealing fit. The end cap 50 is detachably assembled on the top opening of the inner tube body 40.
[0031] In the colloidal gold integrated detection tube provided in this embodiment, the bottom opening 401 of the inner tube body 40 is sealed by the central boss 301 of the intermediate tube body 30, so that the diluent can be stored in the inner tube body 40 in advance; after collecting the sample, the end cap 50 is opened, and the sample is immersed in the diluent of the inner tube body 40. At this time, the end cap 50 can be re-covered, and the sample can be diluted by shaking or the like. After the dilution is completed, the inner tube body 40 is rotated to separate the bottom opening 401 of the inner tube body 40 from the central boss 301, and the diluted sample flows into the accommodating space 101 of the outer tube body 10 through the bottom opening 401 and the through hole 302 in turn, thereby contacting the test paper 21 to achieve antigen detection; the sample dilution and antigen detection are integrated; the process is completed inside the detection tube to avoid harm to the human body due to improper operation.
[0032] Furthermore, in this embodiment, a test paper holder 22 is installed in the outer tube body 10, and the test paper holder 22 is located between the outer tube body 10 and the intermediate tube body 30, and the test paper 21 is fixed on the test paper holder 22; thus, it is convenient to fix the test paper 21. Of course, in other embodiments, the test paper 21 can also be fixed on the inner wall of the outer tube body 10.
[0033] Specifically, the outer tube 10 is a transparent tube, which can visually confirm the detection structure. Of course, in other embodiments, a display window can be opened at the position of the outer tube 10 corresponding to the detection test paper 21, but the sealing of the display window must be ensured; or other methods can be used to confirm the detection result of the detection test paper 21.
[0034] The intermediate tube body 30 includes a first tube section 31 inserted into the outer tube body 10 and a first tube head 32 abutting against the tube mouth of the outer tube body 10; the central boss 301 and the through hole 302 are arranged at the bottom of the first tube section 31. Such arrangement facilitates the positioning and installation of the intermediate tube body 30 and the outer tube body 10, and the installation position is more accurate. Of course, in other embodiments, the structure of the intermediate tube body 30 is not limited to this.
[0035] Meanwhile, the inner tube body 40 includes a second tube section 41 inserted into the first tube section 31 and a second tube head 44 protruding from the first tube head 32; the bottom opening 401 is formed at the bottom of the second tube section 41, and the second tube head 44 includes a screw cap 42 covering the outside of the first tube head 32 and a third tube section 43 protruding from the screw cap 42, and the screw cap 42 is provided with raised ribs, which is convenient for holding and rotating to operate the inner tube body 40 to screw in or out. The second tube section 41 and the third tube section 43 are connected, and the top opening is formed at the top of the third tube head 43; the end cap 50 covers the top of the third tube head 43. Such a configuration facilitates the operation of opening the end cap 50 and screwing out the inner tube body 40, and the structure is simple. Of course, in other embodiments, the structure of the inner tube body 40 is not limited to this, such as not using a structure of the screw cap 42, etc.
[0036] Furthermore, the screw cap 42 of the inner tube body 40 forms a limiting cooperation with the first tube head 32 of the intermediate tube body 30. Specifically, in the present embodiment, the screw cap 42 of the inner tube body 40 has a hook 421 extending inwardly, and the top protrusion of the first tube head 32 has a limiting step 321. When the inner tube body 40 is unscrewed and upwardly separated from the intermediate tube body 30, the upward movement distance of the inner tube body 40 is limited by the cooperation between the hook 421 and the limiting step 321; that is, when the inner tube body 40 is unscrewed, it moves upward relative to the intermediate tube body 30, and when it moves upward to the point where the hook 421 is stuck on the limiting step 321, it cannot continue to move upward and separate; before this, the center boss 301 is separated from the bottom opening 401.
[0037] Specifically, in this embodiment, the inner wall of the intermediate tube body 30 is formed with an internal thread 311, and the bottom outer wall of the inner tube body 40 is provided with an external thread 411, and the inner tube body 40 is threadedly connected by the external thread 411 of the bottom outer wall cooperating with the internal thread 311 of the inner wall of the intermediate tube body 30. Such a configuration does not affect the sealing cooperation between the central boss 301 and the bottom opening 401. Of course, in other embodiments, the position of the threaded connection structure of the inner tube body 40 and the intermediate tube body 30 is not limited to this, such as the external thread can be provided on the central boss 301, and the internal thread cooperating therewith can be provided on the inner wall of the bottom opening 401.
[0038] At the same time, the inner wall of the intermediate tube body 30 and the outer wall of the inner tube body 40 are sealed by a sealing ring 60 to prevent the diluent in the inner tube body 40 from leaking through the gap between the intermediate tube body 30 and the inner tube body 40 when flowing out from the bottom opening 401, thereby improving safety.
[0039] Specifically, in this embodiment, the end cap 50 is a nut, and the end cap 50 is threadedly connected with the inner tube body 40 and assembled on the top opening of the inner tube body 40. As shown in the figure, the third tube section 43 of the inner tube body 40 is provided with an external thread 412, and the external thread 412 is used to be threadedly matched with the end cap 50. The installation of the nut 50 adopts a threaded connection method, which has a simple structure and is easy to operate. More preferably, the tightening direction of the end cap 50 on the inner tube body 40 is opposite to the tightening direction of the inner tube body 40 on the intermediate tube body 30, such as the end cap 50 is screwed on the inner tube body 40 clockwise, and the inner tube body 40 is screwed on the intermediate tube body 30 counterclockwise; to prevent the inner tube body 40 from rotating together when the end cap 50 is unscrewed, causing the bottom opening 401 to be opened.
[0040] Although the present invention has been specifically shown and described in conjunction with the preferred embodiments, it should be understood by those skilled in the art that various changes may be made to the present invention in form and details without departing from the spirit and scope of the present invention as defined by the appended claims, all of which are within the scope of protection of the present invention.
Claims
1. A colloidal gold integrated detection tube, characterized in that: include: An outer tube body, wherein at least one test strip is disposed inside the outer tube body; An intermediate tube body, the intermediate tube body is inserted into the outer tube body, and the bottom of the intermediate tube body is provided with a raised central boss and a through hole located outside the central boss, and the through hole penetrates into the accommodating space of the outer tube body; An inner tube body, wherein the inner tube body is inserted into the middle tube body, the bottom of the inner tube body forms a through bottom opening, the inner tube body and the middle tube body form a threaded assembly, and the center boss of the middle tube body is inserted into the bottom opening of the inner tube body to form a sealing fit; The end cap is detachably mounted on the top opening of the inner tube body.
2. The colloidal gold integrated detection tube according to claim 1, characterized in that: The outer tube body is equipped with a test paper fixing frame, the test paper fixing frame is located between the outer tube body and the middle tube body, and the test paper is fixed on the test paper fixing frame.
3. The colloidal gold integrated detection tube according to claim 1 or 2, characterized in that: A plurality of test strips are arranged in the outer tube.
4. The colloidal gold integrated detection tube according to claim 1 or 2, characterized in that: The outer tube is a transparent tube.
5. The colloidal gold integrated detection tube according to claim 1, characterized in that: The intermediate tube body comprises a first tube section inserted into the outer tube body and a first tube head abutting against the tube opening of the outer tube body; the central boss and the through hole are arranged at the bottom of the first tube section.
6. The colloidal gold integrated detection tube according to claim 5, characterized in that: The inner tube body includes a second tube section inserted into the first tube section and a second tube head protruding from the first tube head; the bottom opening is formed at the bottom of the second tube section, the second tube head includes a screw cap covering the outside of the first tube head and a third tube section protruding from the screw cap, the second tube section and the third tube section are connected, and the top opening is formed at the top of the third tube head.
7. The colloidal gold integrated detection tube according to claim 1, 5 or 6, characterized in that: The inner wall of the intermediate tube body is formed with an internal thread, the bottom outer wall of the inner tube body is provided with an external thread, and the inner tube body is threadedly connected by matching the external thread of the bottom outer wall with the internal thread of the inner wall of the intermediate tube body.
8. The colloidal gold integrated detection tube according to claim 1, 5 or 6, characterized in that: The inner wall of the intermediate tube body and the outer wall of the inner tube body are sealed together by a sealing ring.
9. The colloidal gold integrated detection tube according to claim 1, characterized in that: The end cap is a nut, which is threadedly connected with the inner tube body and assembled on the top opening of the inner tube body.
10. The colloidal gold integrated detection tube according to claim 9, characterized in that: The tightening direction of the end cap on the inner tube body is opposite to the tightening direction of the inner tube body on the middle tube body.