Composition for repairing sensitive skin based on hydrolyzed procyanidine composition

By using hydrolyzed proanthocyanin compositions, the use of ingredients such as honeysuckle compositions to form a bactericidal protective layer and accelerate skin healing, the stubborn problem of hormone-dependent dermatitis is solved, and facial desquamation and itching are significantly improved, and long-term skin repair is achieved Effect.

CN119302893AInactive Publication Date: 2025-01-14GUANGZHOU HANOMEI BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202411472362.0
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-10-22
Publication Date
2025-01-14
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

The prior art is difficult to effectively solve the stubbornness and skin repair problems of hormone-dependent dermatitis, especially in terms of facial appearance.

Method used

Using a hydrolyzed proanthocyanin-based composition, the composition of pre-A liquid and post-B liquid, including honeysuckle composition, licorice, Agnesium, bamboo water, hydrolyzed proanthocyanin and yeast fermentation lysate filtrate and other components, is formed. Bactericidal protective layer and accelerates skin healing, providing moisturizing, antioxidant and whitening effects.

Benefits of technology

It has achieved repairs to sensitive skin, significantly improving facial desquamation and itching in hormone-dependent dermatitis, and no desquamation or itching occurs after long-term use.

✦ Generated by Eureka AI based on patent content.
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Abstract

The invention discloses a composition capable of repairing sensitive skin based on a hydrolyzed procyanidine composition, which comprises a front liquid A and a rear liquid B. The weight ratio of the front liquid A to the rear liquid B is (1-2): (2-3). The invention relates to the technical field of skin repair. According to the composition capable of repairing the sensitive skin based on the hydrolyzed procyanidine composition, the honeysuckle composition, the liquorice, the rhizoma anemarrhenae and the bamboo water form the front liquid A, a sterilization protection layer with a cooling feeling is formed on the surface of the skin, and the skin can be repaired while the skin surface layer is repaired; under the cooperation of hydrolyzed procyanidine and saccharomycetes fermentation lysate filtrate in the rear liquid B, the healing speed of the skin is accelerated, and the moisturizing, antioxidation and whitening effects are provided for the skin.
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Description

Technical Field

[0001] The invention relates to the technical field of skin repair, and in particular to a composition based on a hydrolyzed proanthocyanidin composition capable of repairing sensitive skin. Background Art

[0002] Corticosteroid-dependent dermatitis, also known as hormone-dependent dermatitis, is a dermatitis caused by long-term, repeated and improper use of topical hormones. It is characterized by the disappearance of primary skin lesions after the application of topical corticosteroids, but the reappearance of inflammatory lesions after discontinuation of use. Repeated use of corticosteroids is required to control the symptoms and the dermatitis gradually worsens. It is stubborn and difficult to cure, and seriously affects the appearance of the face. Summary of the invention

[0003] 1. Technical issues to be resolved

[0004] In view of the deficiencies in the prior art, the present invention provides a composition based on a hydrolyzed proanthocyanidin composition that has the function of repairing sensitive skin, thereby solving the above-mentioned problems.

[0005] (II) Technical solution

[0006] To achieve the above objectives, the present invention is implemented by the following technical scheme: A composition for repairing sensitive skin based on a hydrolyzed proanthocyanidin composition, comprising a pre-liquid A and a post-liquid B, wherein the pre-liquid A and the post-liquid B are in a weight ratio of 1-2:2-3;

[0007] The raw materials of the pre-liquid A include, by weight: 11-18 parts of honeysuckle composition, 5-10 parts of liquorice, 1-5 parts of rhizoma anemarrhenae, and 65-92 parts of bamboo water;

[0008] The raw materials of the post-liquid B include, by weight: 79-97 parts of deionized water, 3-15 parts of hydrolyzed proanthocyanidins, 1-3 parts of yeast fermentation lysate filtrate, 1-3 parts of preservatives, 0.1-1 parts of sodium hyaluronate, 0.1-0.5 parts of allantoin, and 1-5 parts of butanediol.

[0009] The present invention is further configured as follows: the weight ratio of the front liquid A and the rear liquid B is 1:2;

[0010] The raw materials of the pre-liquid A include, by weight: 11 parts of honeysuckle composition, 5 parts of liquorice, 1 part of rhizoma anemarrhenae, and 65 parts of bamboo water;

[0011] The raw materials of the post-liquid B include, by weight: 85 parts of deionized water, 9 parts of hydrolyzed proanthocyanidins, 2 parts of yeast fermentation lysate filtrate, 2 parts of preservatives, 0.3 parts of sodium hyaluronate, 0.3 parts of allantoin, and 3 parts of butanediol.

[0012] The present invention is further configured as follows: the weight ratio of the front liquid A and the rear liquid B is: 1:3;

[0013] The raw materials of the pre-liquid A include, by weight: 15 parts of honeysuckle composition, 8 parts of liquorice, 3 parts of rhizoma anemarrhenae, and 80 parts of bamboo water;

[0014] The raw materials of the post-liquid B include, by weight: 97 parts of deionized water, 15 parts of hydrolyzed proanthocyanidins, 3 parts of yeast fermentation lysate filtrate, 3 parts of preservatives, 1 part of sodium hyaluronate, 0.5 parts of allantoin, and 5 parts of butanediol.

[0015] The present invention is further configured as follows: the weight ratio of the front liquid A and the rear liquid B is 2:2;

[0016] The raw materials of the pre-liquid A include, by weight: 18 parts of honeysuckle composition, 10 parts of liquorice, 5 parts of rhizoma anemarrhenae, and 92 parts of bamboo water;

[0017] The raw materials of the post-liquid B include, by weight: 79 parts of deionized water, 3 parts of hydrolyzed proanthocyanidins, 1 part of yeast fermentation lysate filtrate, 1 part of preservative, 0.1 part of sodium hyaluronate, 0.1 part of allantoin, and 1 part of butanediol.

[0018] The present invention is further configured as follows: the honeysuckle composition comprises, by weight: 15 parts of honeysuckle, 3 parts of dried orange peel and 7 parts of mint;

[0019] The preparation process of the honeysuckle composition comprises:

[0020] Weigh corresponding weights of honeysuckle, tangerine peel and mint in a ratio of 15:3:7, grind the honeysuckle, tangerine peel and mint into powder, and stir them evenly to obtain a honeysuckle composition.

[0021] The present invention is further configured as follows: the preparation process of the bamboo water comprises:

[0022] Add 1000g of fresh bamboo leaves into 8000g of water, boil, keep for 15min, cool to 50℃, add 200g of honey, stir evenly, keep warm for 10min, and obtain bamboo water.

[0023] The present invention is further configured as follows: the preservative is composed of one or more of perilla extract, tea tree essential oil and pectin.

[0024] The present invention is further configured as follows: the preparation process of the pre-liquid A comprises:

[0025] Grind liquorice and rhizoma anemarrhenae into powder in sequence, add honeysuckle composition, stir evenly, obtain added powder, heat bamboo water to 30°C, add added powder, stir evenly, keep warm for 1-2h, and obtain pre-liquid A;

[0026] The preparation process of the pre-liquid B comprises:

[0027] The yeast fermentation lysate filtrate and preservatives are sequentially added into deionized water and stirred evenly to obtain a base solution, and hydrolyzed proanthocyanidins, sodium hyaluronate, allantoin and butanediol are added and stirred evenly to obtain a post-treatment solution B.

[0028] (III) Beneficial effects

[0029] The present invention provides a composition for repairing sensitive skin based on a hydrolyzed proanthocyanidin composition. It has the following beneficial effects:

[0030] The present invention uses a honeysuckle composition, liquorice, rhizoma anemarrhenae and bamboo water to form a pre-liquid A, which forms a bactericidal protective layer with a cooling feeling on the skin surface, while repairing the skin surface. At the same time, with the cooperation of hydrolyzed proanthocyanidins and yeast fermentation lysate filtrate in the post-liquid B, the skin healing speed is accelerated, and the skin is provided with moisturizing, anti-oxidation and whitening effects. DETAILED DESCRIPTION

[0031] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0032] The embodiment of the present invention provides the following technical solutions:

[0033] Embodiment 1

[0034] A composition for repairing sensitive skin based on a hydrolyzed proanthocyanidin composition comprises a front liquid A and a rear liquid B, wherein the weight ratio of the front liquid A to the rear liquid B is 1:2.

[0035] The raw materials of the pre-liquid A include, by weight: 11 parts of honeysuckle composition, 5 parts of liquorice, 1 part of rhizoma anemarrhenae, and 65 parts of bamboo water. The preparation process of the pre-liquid A includes:

[0036] Weigh the corresponding honeysuckle composition, licorice, anemarrhena asphodeloides, and bamboo water in a weight ratio of 11:5:1:65, grind the licorice and anemarrhena asphodeloides into powder in turn, add the honeysuckle composition, stir evenly to obtain added powder, heat the bamboo water to 30°C, add the added powder, stir evenly, and keep warm for 1-2 hours to obtain pre-liquid A.

[0037] The honeysuckle composition comprises, by weight: 15 parts of honeysuckle, 3 parts of dried orange peel and 7 parts of mint;

[0038] The preparation process of the honeysuckle composition comprises:

[0039] Weigh corresponding weights of honeysuckle, tangerine peel and mint in a ratio of 15:3:7, grind the honeysuckle, tangerine peel and mint into powder, and stir them evenly to obtain a honeysuckle composition.

[0040] Among them, the preparation process of bamboo water includes:

[0041] Add 1000g of fresh bamboo leaves into 8000g of water, boil, keep for 15min, cool to 50℃, add 200g of honey, stir evenly, keep warm for 10min, and obtain bamboo water.

[0042] The raw materials of the post-B solution include, by weight: 85 parts of deionized water, 9 parts of hydrolyzed proanthocyanidins, 2 parts of yeast fermentation lysate filtrate, and 2 parts of preservatives. The preparation process of the pre-B solution includes:

[0043] Weigh the corresponding deionized water, hydrolyzed proanthocyanidins, yeast fermentation lysate filtrate, preservatives, sodium hyaluronate, allantoin and butanediol in a weight ratio of 85:22:9:2:2:2:0.3:0.3:3; add the yeast fermentation lysate filtrate and the preservatives into the deionized water in turn, stir evenly to obtain the base solution; add the hydrolyzed proanthocyanidins, sodium hyaluronate, allantoin and butanediol, stir evenly to obtain the post-liquid B.

[0044] Wherein, the preservative is one or more of perilla extract, tea tree essential oil and pectin.

[0045] Embodiment 2

[0046] A composition for repairing sensitive skin based on a hydrolyzed proanthocyanidin composition, comprising a pre-liquid A and a post-liquid B, wherein the pre-liquid A and the post-liquid B are in a weight ratio of 1:3;

[0047] The raw materials of the pre-liquid A include, by weight: 15 parts of honeysuckle composition, 8 parts of liquorice, 3 parts of rhizoma anemarrhenae, and 80 parts of bamboo water. The preparation process of the pre-liquid A includes:

[0048] Weigh the corresponding honeysuckle composition, licorice, anemarrhena asphodeloides, and bamboo water in a weight ratio of 15:8:3:80, grind the licorice and anemarrhena asphodeloides into powder in turn, add the honeysuckle composition, stir evenly to obtain added powder, heat the bamboo water to 30°C, add the added powder, stir evenly, and keep warm for 1-2 hours to obtain pre-liquid A.

[0049] The honeysuckle composition comprises, by weight: 15 parts of honeysuckle, 3 parts of dried orange peel and 7 parts of mint;

[0050] The preparation process of the honeysuckle composition comprises:

[0051] Weigh corresponding weights of honeysuckle, tangerine peel and mint in a ratio of 15:3:7, grind the honeysuckle, tangerine peel and mint into powder, and stir them evenly to obtain a honeysuckle composition.

[0052] Among them, the preparation process of bamboo water includes:

[0053] Add 1000g of fresh bamboo leaves into 8000g of water, boil, keep for 15min, cool to 50℃, add 200g of honey, stir evenly, keep warm for 10min, and obtain bamboo water.

[0054] The raw materials of the post-B liquid include, by weight: 97 parts of deionized water, 15 parts of hydrolyzed proanthocyanidins, 3 parts of yeast fermentation lysate filtrate, and 3 parts of preservatives. The preparation process of the pre-B liquid includes:

[0055] Weigh the corresponding deionized water, hydrolyzed proanthocyanidins, yeast fermentation lysate filtrate, preservatives, sodium hyaluronate, allantoin and butanediol in a weight ratio of 97:27:15:2:3:3:1:0.5:5; add the yeast fermentation lysate filtrate and preservatives into deionized water in turn, stir evenly to obtain a base solution; add hydrolyzed proanthocyanidins, sodium hyaluronate, allantoin and butanediol, stir evenly to obtain a post-treatment solution B.

[0056] Embodiment 3

[0057] A composition based on a hydrolyzed proanthocyanidin composition having the function of repairing sensitive skin, comprising a pre-liquid A and a post-liquid B, wherein the pre-liquid A and the post-liquid B are in a weight ratio of 2:2;

[0058] The raw materials of the pre-liquid A include, by weight: 18 parts of honeysuckle composition, 10 parts of liquorice, 5 parts of rhizoma anemarrhenae, and 92 parts of bamboo water. The preparation process of the pre-liquid A includes:

[0059] Weigh the corresponding honeysuckle composition, licorice, anemarrhena asphodeloides, and bamboo water in a weight ratio of 18:10:5:92, grind the licorice and anemarrhena asphodeloides into powder in turn, add the honeysuckle composition, stir evenly to obtain added powder, heat the bamboo water to 30°C, add the added powder, stir evenly, and keep warm for 1-2 hours to obtain pre-liquid A.

[0060] The honeysuckle composition comprises, by weight: 15 parts of honeysuckle, 3 parts of dried orange peel and 7 parts of mint;

[0061] The preparation process of the honeysuckle composition comprises:

[0062] Weigh corresponding weights of honeysuckle, tangerine peel and mint in a ratio of 15:3:7, grind the honeysuckle, tangerine peel and mint into powder, and stir them evenly to obtain a honeysuckle composition.

[0063] Among them, the preparation process of bamboo water includes:

[0064] Add 1000g of fresh bamboo leaves into 8000g of water, boil, keep for 15min, cool to 50℃, add 200g of honey, stir evenly, keep warm for 10min, and obtain bamboo water.

[0065] The raw materials of the post-B solution include, by weight: 79 parts of deionized water, 3 parts of hydrolyzed proanthocyanidins, 1 part of yeast fermentation lysate filtrate, and 1 part of preservative. The preparation process of the pre-B solution includes:

[0066] Weigh the corresponding deionized water, hydrolyzed proanthocyanidins, yeast fermentation lysate filtrate, preservatives, sodium hyaluronate, allantoin and butanediol in a weight ratio of 79:16:3:1:1:1:0.1:0.1:1; add the yeast fermentation lysate filtrate and preservatives into deionized water in turn, stir evenly to obtain the base solution; add the hydrolyzed proanthocyanidins, sodium hyaluronate, allantoin and butanediol, stir evenly to obtain the post-treatment solution B.

[0067] According to the preparation method of the first embodiment, sample 1 pre-A liquid and sample 1 pre-B liquid are obtained. According to the preparation method of the second embodiment, sample 2 pre-A liquid and sample 2 pre-B liquid are obtained. According to the preparation method of the third embodiment, sample 3 pre-A liquid and sample 3 pre-B liquid are obtained.

[0068] Irritation test:

[0069] Six New Zealand white rabbits were taken, and the fur on both sides of the rabbits' back spine was cut off, with an area of ​​3cm*3cm. Sample 1 pre-liquid A was taken and applied to one side of the skin of two rabbits, with an application area of ​​2.5cm*2.5cm. After 5 minutes, sample 1 pre-liquid B was taken and applied again to the sample 1 pre-liquid A application area as the test area. The other side was not treated as the control area. The application was performed once a day for 7 consecutive days. Starting from the second day, the fur was cut before each application, and the residual test sample was removed with pure water. The test results were observed after one hour, and the test area was compared with the control area. It was found that sample 1 pre-liquid A and sample 1 pre-liquid B were not irritating to the surface of the rabbits.

[0070] Six New Zealand white rabbits were taken, and the fur on both sides of the rabbits' back spine was cut off, with an area of ​​3cm*3cm. Sample 2 pre-treatment liquid A was taken and applied to one side of the skin of two rabbits, with an application area of ​​2.5cm*2.5cm. After 5 minutes, sample 2 pre-treatment liquid B was taken and applied again to the sample 2 pre-treatment liquid A application area as the test area. The other side was not treated as the control area. The application was performed once a day for 7 consecutive days. From the second day, the fur was cut before each application, and the residual test sample was removed with pure water. The test results were observed after one hour, and the test area was compared with the control area. It was found that sample 2 pre-treatment liquid A and sample 2 pre-treatment liquid B were not irritating to the surface of the rabbits.

[0071] Six New Zealand white rabbits were taken, and the fur on both sides of the rabbits' spine on the back was cut off, with an area of ​​3cm*3cm. Sample 3 pre-treatment liquid A was taken and applied on one side of the skin of two rabbits, with an application area of ​​2.5cm*2.5cm. After 5 minutes, sample 3 pre-treatment liquid B was taken and applied again on the application area of ​​sample 3 pre-treatment liquid A as the test area. The other side was left untreated as the control area. The application was performed once a day for 7 consecutive days. Starting from the second day, the fur was trimmed before each application, and the residual test sample was removed with pure water. The test results were observed after one hour, and the test area was compared with the control area. It was found that sample 3 pre-treatment liquid A and sample 3 pre-treatment liquid B were not irritating to the surface of the rabbits.

[0072] Practical Applications

[0073] Gao suffered from hormone-dependent dermatitis on his face for three years, and his facial desquamation and itching became increasingly severe. He selected the sample three pre-treatment liquid A and sample three pre-treatment liquid B prepared in the third embodiment for application. First, the sample three pre-treatment liquid A was evenly applied on the face. After massaging for 5 minutes, the sample three pre-treatment liquid B was applied. After repeating this for 7 days, the facial desquamation and itching were effectively improved. After 22 days, there was no desquamation and itching on the face. After stopping use for three months, there was no desquamation and itching on the face.

[0074] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions. The sentence "includes an element defined by ... does not exclude the existence of other identical elements in the process, method, article or device including the element".

[0075] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A composition for repairing sensitive skin based on a hydrolyzed proanthocyanidin composition, characterized in that: It includes a front liquid A and a rear liquid B, wherein the weight ratio of the front liquid A and the rear liquid B is 1-2:2-3; The raw materials of the pre-liquid A include, by weight: 11-18 parts of honeysuckle composition, 5-10 parts of liquorice, 1-5 parts of rhizoma anemarrhenae, and 65-92 parts of bamboo water; The raw materials of the post-liquid B include, by weight: 79-97 parts of deionized water, 3-15 parts of hydrolyzed proanthocyanidins, 1-3 parts of yeast fermentation lysate filtrate, 1-3 parts of preservatives, 0.1-1 parts of sodium hyaluronate, 0.1-0.5 parts of allantoin, and 1-5 parts of butanediol.

2. The composition for repairing sensitive skin based on the hydrolyzed proanthocyanidins composition according to claim 1, characterized in that: The weight ratio of the front liquid A and the rear liquid B is 1:2; The raw materials of the pre-liquid A include, by weight: 11 parts of honeysuckle composition, 5 parts of liquorice, 1 part of rhizoma anemarrhenae, and 65 parts of bamboo water; The raw materials of the post-liquid B include, by weight: 85 parts of deionized water, 9 parts of hydrolyzed proanthocyanidins, 2 parts of yeast fermentation lysate filtrate, 2 parts of preservatives, 0.3 parts of sodium hyaluronate, 0.3 parts of allantoin, and 3 parts of butanediol.

3. The composition for repairing sensitive skin based on the hydrolyzed proanthocyanidins composition according to claim 1, characterized in that: The weight ratio of the front liquid A and the rear liquid B is 1:3; The raw materials of the pre-liquid A include, by weight: 15 parts of honeysuckle composition, 8 parts of liquorice, 3 parts of rhizoma anemarrhenae, and 80 parts of bamboo water; The raw materials of the post-liquid B include, by weight: 97 parts of deionized water, 15 parts of hydrolyzed proanthocyanidins, 3 parts of yeast fermentation lysate filtrate, 3 parts of preservatives, 1 part of sodium hyaluronate, 0.5 parts of allantoin, and 5 parts of butanediol.

4. The composition for repairing sensitive skin based on the hydrolyzed proanthocyanidins composition according to claim 1, characterized in that: The weight ratio of the front liquid A and the rear liquid B is 2:2; The raw materials of the pre-liquid A include, by weight: 18 parts of honeysuckle composition, 10 parts of liquorice, 5 parts of rhizoma anemarrhenae, and 92 parts of bamboo water; The raw materials of the post-liquid B include, by weight: 79 parts of deionized water, 3 parts of hydrolyzed proanthocyanidins, 1 part of yeast fermentation lysate filtrate, 1 part of preservative, 0.1 part of sodium hyaluronate, 0.1 part of allantoin, and 1 part of butanediol.

5. A composition for repairing sensitive skin based on a hydrolyzed proanthocyanidin composition according to any one of claims 1 to 4, characterized in that: The honeysuckle composition comprises, by weight: 15 parts of honeysuckle, 3 parts of dried orange peel and 7 parts of mint; The preparation process of the honeysuckle composition comprises: Weigh corresponding weights of honeysuckle, tangerine peel and mint in a ratio of 15:3:7, grind the honeysuckle, tangerine peel and mint into powder, and stir them evenly to obtain a honeysuckle composition.

6. A composition for repairing sensitive skin based on a hydrolyzed proanthocyanidin composition according to any one of claims 1 to 4, characterized in that: The preparation process of the bamboo water comprises: Add 1000g of fresh bamboo leaves into 8000g of water, boil, keep for 15min, cool to 50℃, add 200g of honey, stir evenly, keep warm for 10min, and obtain bamboo water.

7. A composition for repairing sensitive skin based on a hydrolyzed proanthocyanidin composition according to any one of claims 1 to 4, characterized in that: The preservative is composed of one or more of perilla extract, tea tree essential oil and pectin.

8. A composition for repairing sensitive skin based on a hydrolyzed proanthocyanidin composition according to any one of claims 1 to 4, characterized in that: The preparation process of the pre-liquid A comprises: Grind liquorice and rhizoma anemarrhenae into powder in sequence, add honeysuckle composition, stir evenly, obtain added powder, heat bamboo water to 30°C, add added powder, stir evenly, keep warm for 1-2h, and obtain pre-liquid A; The preparation process of the pre-liquid B comprises: The yeast fermentation lysate filtrate and preservatives are sequentially added into deionized water and stirred evenly to obtain a base solution, and hydrolyzed proanthocyanidins, sodium hyaluronate, allantoin and butanediol are added and stirred evenly to obtain a post-treatment solution B.