Clindamycin hydrochloride reaction device

Abstract

The invention discloses a clindamycin hydrochloride reaction device, and particularly relates to the technical field of clindamycin hydrochloride processing.The device comprises a reaction tank, a stirring mechanism, a guiding assembly, a shaking assembly, a containing groove, a grating and a positioning assembly, shaft rods are welded to the two sides of the top end of the reaction tank, and the reaction tank is connected with a bottom plate through a fixing assembly; supporting assemblies with pulleys are mounted on two sides of the bottom end; the stirring mechanism is used for stirring raw materials; the guide assembly guides the pulley; the shaking assembly is matched with the stirring mechanism to shake the reaction tank and can also be used for discharging; the containing groove receives products; the grating detects the position of the containing groove; and the positioning assembly is used for guiding, clamping and positioning the containing groove. The problems that a traditional clindamycin hydrochloride reaction device is uneven in stirring, incomplete in discharging and the like are solved, the reaction efficiency, the product purity, the discharging efficiency and the stability of the device are improved through the synergistic effect of all the assemblies, and the device is suitable for production and preparation of clindamycin hydrochloride.

Description

Technical Field

[0001] The invention relates to the technical field of clindamycin hydrochloride processing, and more specifically to a clindamycin hydrochloride reaction device. Background Art

[0002] Clindamycin hydrochloride is an antibiotic drug and a derivative of lincomycin. It has strong antibacterial effects and is mainly used clinically for osteomyelitis, infections caused by anaerobic bacteria, respiratory system infections, biliary tract infections, endocarditis, otitis media, skin and soft tissue infections, and sepsis. Clindamycin hydrochloride requires a raw material reaction device for preparation during the production process.

[0003] In the production process of clindamycin hydrochloride, the performance of the reaction device plays a vital role in the quality, output and production efficiency of the product. Traditional clindamycin hydrochloride production reaction devices mostly rely on a single stirring method to achieve the mixing of the reaction materials.

[0004] There are many defects when only stirring operation is adopted. The stirring paddle rotates in the reactor. Although it can promote the flow of materials to a certain extent, it is difficult to ensure the uniform mixing of materials in the entire reaction system. Due to the presence of different flow rate areas in the reactor, especially the part away from the stirring paddle, it is easy to form a mixing dead angle. For example, in the reaction link involving solid catalysts and liquid reactants, the solid catalyst tends to gradually settle to the bottom of the reactor due to gravity, resulting in it not being able to fully contact the reactants, so that the reaction can only be effectively carried out in a local range, greatly reducing the overall reaction efficiency. Moreover, uneven mixing will also affect the selectivity of the reaction. For example, in the halogenation reaction step, the local concentration difference of the halogenating agent caused by uneven stirring may cause side reactions such as over-halogenation, resulting in reduced product purity.

[0005] At the same time, for gas-liquid reactions or liquid-liquid reactions, simple stirring is obviously insufficient in terms of mass transfer. In gas-liquid reactions, the gas-liquid contact area produced by stirring is limited, and the dissolution and diffusion rate of the gas in the liquid is slow, which restricts the rapid advancement of the reaction. Taking the reaction involving hydrogen chloride gas as an example, the traditional stirring method makes it difficult for the hydrogen chloride gas to be fully dispersed in the reaction liquid and participate in the reaction, which prolongs the reaction time. In liquid-liquid reactions, such as when the organic phase solvent reacts with the aqueous phase alkali solution, stirring is difficult to fully update the interface between the two phases, and the transfer efficiency of the reactants between the phases is low, which is not conducive to the efficient completion of the reaction.

[0006] In addition, there are also problems with the discharge of traditional reaction devices. Generally, the discharge is carried out by gravity or simple pressure difference. For reaction liquids with high viscosity, the discharge speed is slow and the residual amount in the reactor is large. This not only reduces production efficiency, but also may cause part of the product to remain in the reactor, resulting in material waste, increased production costs, and may affect the starting conditions of the next batch of reactions and the stability of product quality.

[0007] Therefore, a clindamycin hydrochloride reaction device is now proposed. Summary of the invention

[0008] In order to overcome the above defects of the prior art, the present invention provides a clindamycin hydrochloride reaction device to solve the problems raised in the above background technology.

[0009] To achieve the above object, the present invention provides the following technical solution: a clindamycin hydrochloride reaction device, comprising: A reaction tank, wherein shaft rods are welded on both sides of the top of the reaction tank, two shaft sleeves are sleeved on each shaft rod, and the two shaft rods are commonly connected to a fixing assembly, a bottom plate is installed at the bottom of the fixing assembly, and ramp plates are arranged on both sides of the bottom plate, and support assemblies are installed on both sides of the bottom end of the reaction tank, and the support assembly includes a support rod and a pulley, and the pulley is installed on the support rod; A stirring mechanism, wherein the stirring mechanism is installed on the reaction tank; A guide assembly, wherein the guide assembly is mounted on the fixed assembly, the guide assembly is connected and matched with two pulleys, and the guide assembly is used to guide the pulleys; A shaking assembly, wherein two shaking assemblies are provided, each of which is connected to a corresponding support rod, and the shaking assembly is used to cooperate with the stirring mechanism to shake and stir the reaction tank, and the shaking assembly is also used to discharge the reaction tank; A containing tank, the containing tank being arranged on the bottom plate and used for receiving the produced clindamycin hydrochloride; Gratings, wherein two groups of gratings are provided, one group of gratings is installed at the front end of the inner side of the fixed component, and the other group of gratings is installed at the rear end of the inner side of the fixed component, and the two groups of gratings are used to detect the position of the bottom plate where the containing slot is located; Positioning components, two of which are provided, each of which is provided on both sides of the containing slot, and the two positioning components are used for guiding and clamping the containing slot for positioning.

[0010] Preferably, a top cover is installed on the top of the reaction tank, and a sealing ring is provided between the top cover and the reaction tank.

[0011] Preferably, feeding ports are provided on both sides of the top of the reaction tank, and a sealing cover is screwed on each feeding port. The bottom of the reaction tank is an arc-shaped structure, and a discharge pipe is installed at the bottom of the reaction tank, and a solenoid valve is installed on the discharge pipe.

[0012] Preferably, the stirring mechanism includes a motor, a stirring shaft, a first stirring rod, a second stirring rod, and a third stirring rod. The motor is installed on the top cover, and the output end of the motor is connected to the stirring shaft rotatably connected to the top cover. Multiple groups of first stirring rods are installed on the stirring shaft, and each group of first stirring rods is internally connected to two second stirring rods, and each group of first stirring rods is connected by multiple third stirring rods.

[0013] Preferably, the fixing assembly includes a fixing bracket and a fixing pressure plate, and two fixing brackets and two fixing pressure plates are provided. The bottom ends of the two fixing brackets are connected by a bottom plate, and a fixing pressure plate is installed on the top of each fixing bracket, and two fixing beams are connected to the top of the two fixing brackets.

[0014] Preferably, a semicircular shaft groove and a semicircular groove are provided at the top end of the fixed bracket and the bottom end of the fixed pressure plate. The fixed bracket and the fixed pressure plate are connected so that the two semicircular shaft grooves are connected to form an shaft hole, and the upper and lower connected semicircular grooves are connected to form a clamping groove. The shaft rod is inserted into the shaft hole, and the shaft sleeve is clamped in the clamping groove.

[0015] Preferably, a support plate is welded on the inner side of each of the fixed brackets, and the two support plates respectively support a shaking assembly connected to the support rod.

[0016] Preferably, the shaking assembly includes a first hydraulic rod, a second hydraulic rod and a base, one end of the first hydraulic rod and the second hydraulic rod are hinged on the support rod, the other ends of the first hydraulic rod and the second hydraulic rod are respectively connected to two bases installed on the support plate, and the first hydraulic rod and the second hydraulic rod are both connected to a hydraulic pump.

[0017] Preferably, the guide assembly includes a cross bar and a guide frame, and two of the cross bar and the guide frame are provided, and both ends of the two cross bars are connected to the fixed bracket. The guide frame includes two arc frames and two connecting blocks. The two arc frames are arranged in parallel, and the two ends of the two arc frames are respectively connected to the corresponding connecting blocks, and each connecting block is respectively connected to the corresponding cross bar. An arc guide groove is formed between the two arc frames, and the pulley is installed in the arc guide groove. The arc center of the arc guide groove coincides with the axis center line of the shaft.

[0018] Preferably, the positioning assembly comprises an electric push rod and a push plate, and one side of the push plate is connected to two electric push rods mounted on a fixed bracket.

[0019] Technical effects and advantages of the present invention: 1. Through the cooperation of the stirring mechanism and the shaking assembly, the reaction tank can shake left and right during the stirring process to avoid partial precipitation of the raw materials at the bottom during the stirring process, so that the raw materials can fluctuate and collide with the stirring rod due to centrifugal effect, further disperse the raw materials, achieve more uniform mixing, fully react, and improve the reaction efficiency and the purity of clindamycin hydrochloride after the reaction.

[0020] 2. When discharging after the reaction is completed, gravity is used first. When the discharging speed decreases, the shaking component cooperates with the stirring mechanism to operate again, so that the clindamycin hydrochloride remaining in the reaction tank produces centrifugal motion and is thrown out from the discharge pipe into the containing tank to avoid the material liquid from adhering to the inner wall of the reaction tank due to its high viscosity, thereby improving the discharge efficiency and thoroughness.

[0021] 3. The pulley at the bottom of the reaction tank is guided by the guide assembly, and the arc center of the arc guide groove coincides with the axis center line of the shaft rod, ensuring that the movement trajectory of the reaction tank is accurate and stable during shaking, stirring, discharging and tilting, avoiding excessive shaking or deviation from the predetermined trajectory.

[0022] 4. The holding tank can be accurately positioned by the positioning assembly in conjunction with the grating. The push plates and bottom plate on both sides of the holding tank form a guide channel. The extension of the electric push rod can clamp the holding tank with the push plate to ensure that the holding tank is accurately placed at the predetermined position on the bottom plate, avoiding vibration caused by shaking of the reaction tank and causing the holding tank to shift, ensuring that the holding tank can accurately receive the clindamycin hydrochloride discharged from the reaction tank.

[0023] 5. A sealing ring is set between the top cover on the top of the reaction tank and the reaction tank, and the sealing cover is screwed on the feeding port to ensure the sealing performance of the reaction tank, prevent material leakage and external impurities from entering and affecting the reaction, and ensure that the reaction is carried out in a sealed environment.

[0024] 6. The arc-shaped structure at the bottom of the reaction tank facilitates the flow and discharge of materials in the tank, and is conducive to the shaking operation with the shaking component to make the material liquid centrifugally fluctuate better. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 It is a schematic diagram of the overall structure of the present invention.

[0026] Figure 2 It is a schematic diagram of the connection structure between the guide assembly and the shaking assembly of the present invention.

[0027] Figure 3 It is a schematic diagram of the connection structure of the reaction tank of the present invention.

[0028] Figure 4 It is a structural schematic diagram of the stirring mechanism of the present invention.

[0029] Figure 5 It is a schematic diagram of the installation structure of the fixing component of the present invention.

[0030] Figure 6 For the present invention Figure 5 Schematic diagram of the local enlarged structure at point A in the middle.

[0031] Figure 7 It is a schematic structural diagram of the positioning component of the present invention.

[0032] The accompanying drawings are marked as follows: 1. reaction tank; 2. stirring mechanism; 201. motor; 202. stirring shaft; 203. first stirring rod; 204. second stirring rod; 205. third stirring rod; 3. support assembly; 301. support rod; 302. pulley; 4. fixing assembly; 401. fixing bracket; 402. fixing pressure plate; 5. support plate; 6. shaking assembly; 601. first hydraulic rod; 602. second hydraulic rod; 603. base; 7. guide assembly; 701. cross bar; 702. guide frame; 8. bottom plate; 9. holding tank; 10. ramp plate; 11. positioning assembly; 1101. electric push rod; 1102. push plate; 12. shaft rod; 13. bushing; 14. top cover; 15. sealing ring; 16. feeding port; 17. fixed beam; 18. grating. DETAILED DESCRIPTION

[0033] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0034] As attached Figure 1-7 A clindamycin hydrochloride reaction device is shown, comprising: A reaction tank 1, wherein shaft rods 12 are welded on both sides of the top of the reaction tank 1, and two shaft sleeves 13 are sleeved on each of the shaft rods 12, and the two shaft rods 12 are commonly connected to a fixing component 4, a bottom plate 8 is installed at the bottom of the fixing component 4, and ramp plates 10 are arranged on both sides of the bottom plate 8, and support components 3 are installed on both sides of the bottom end of the reaction tank 1, and the support component 3 includes a support rod 301 and a pulley 302, and the pulley 302 is installed on the support rod 301; A stirring mechanism 2, wherein the stirring mechanism 2 is installed on the reaction tank 1; A guide assembly 7, wherein the guide assembly 7 is mounted on the fixed assembly 4, and the guide assembly 7 is connected and matched with two pulleys 302, and the guide assembly 7 is used to guide the pulleys 302; A shaking assembly 6, wherein two shaking assemblies 6 are provided, each of which is connected to a corresponding support rod 301, and the shaking assembly 6 is used to cooperate with the stirring mechanism 2 to shake and stir the reaction tank 1, and the shaking assembly 6 is also used to discharge the reaction tank 1; A containing tank 9, wherein the containing tank 9 is arranged on the bottom plate 8 and is used for receiving the produced clindamycin hydrochloride; Gratings 18, wherein two groups of gratings 18 are provided, one group of gratings 18 is installed at the front end of the inner side of the fixing component 4, and the other group of gratings 18 is installed at the rear end of the inner side of the fixing component 4, and the two groups of gratings 18 are used to detect the position of the containing slot 9 on the bottom plate 8; The positioning components 11 are provided with two, and each of the positioning components 11 is respectively provided at two sides of the containing groove 9 , and the two positioning components 11 are used for guiding and clamping the containing groove 9 for positioning.

[0035] In a specific implementation, the positioning components 11 installed on both sides of the bottom plate 8 cooperate to form a guide channel. When the holding tank 9 moves from the ramp plate 10 on one side to the port of the guide channel, the grating 18 of the port detects the position of the holding tank 9, and the holding tank 9 continues to move. When the connection signal of the grating 18 at the other end is blocked and the grating 18 signal entering the port is also in a disconnected state, the movement of the holding tank 9 is stopped to achieve automatic positioning, and then the positioning components 11 on both sides clamp and fix the holding tank 9 to accurately receive the clindamycin hydrochloride discharged from the reaction tank 1; When processing clindamycin hydrochloride, firstly, the raw material is put into the reaction tank 1 from the feeding port 16, the feeding port 16 is closed, and the stirring mechanism 2 is operated to stir the raw material in the reaction tank 1. In order to prevent the raw material from generating bottom precipitation during the stirring process, the shaking components 6 on both sides are operated to make the reaction tank 1 rotate with the two shaft rods 12 as the rotating shaft, and the guide component 7 supports the pulley 302 on the support rod 301 and guides the movement of the pulley 302, so that the reaction tank 1 can be stably shaken left and right. When the reaction tank 1 shakes, the raw material in the reaction tank 1 fluctuates due to the centrifugal effect of the shaking, collides with each stirring rod in the process of fluctuating, and is dispersed again, thereby further improving the stirring effect, making the raw material mixing more uniform, being able to react more fully, and improving the reaction efficiency and the purity of the clindamycin hydrochloride after the reaction; After the reaction is completed, when the clindamycin hydrochloride produced in the reaction tank 1 needs to be discharged, first, the reaction tank 1 is adjusted to a vertical state, and the solenoid valve opens the discharge pipe for discharge. After the discharge speed is reduced, the shaking component 6 cooperates with the stirring mechanism 2 to operate again, so that the clindamycin hydrochloride remaining in the reaction tank 1 is centrifuged, so that the clindamycin hydrochloride remaining in the reaction tank 1 is directly thrown out from the discharge pipe into the holding tank 9, so as to avoid the material liquid being attached to the inner wall of the reaction tank 1 due to excessive viscosity and being difficult to discharge, thereby improving the discharge efficiency and the thoroughness of the discharge.

[0036] As attached Figure 3As shown, a top cover 14 is installed on the top of the reaction tank 1, a sealing ring 15 is arranged between the top cover 14 and the reaction tank 1, feeding ports 16 are arranged on both sides of the top of the reaction tank 1, and a sealing cover is screwed on each of the feeding ports 16. The bottom of the reaction tank 1 is an arc-shaped structure, and a discharge pipe is installed at the bottom of the reaction tank 1, and a solenoid valve is installed on the discharge pipe.

[0037] During specific implementation, a sealing ring 15 is provided between the top cover 14 and the reaction tank 1 to ensure the sealing performance of the reaction tank 1, prevent material leakage and external impurities from entering the reaction tank 1 to affect the reaction. When loading, the sealing cover is opened, and raw materials are added to the reaction tank 1 through the loading port 16. After the loading is completed, the sealing cover is tightened to ensure that the reaction process is carried out in a sealed environment. The bottom of the reaction tank 1 is an arc-shaped structure, which is convenient for the flow and discharge of materials in the reaction tank 1, so that it is convenient to shake the reaction tank 1 in cooperation with the shaking component 6, so that the internal material liquid fluctuates centrifugally. When discharging, the opening and closing of the discharge pipe is controlled by the solenoid valve, and the material can be discharged through the discharge pipe with the assistance of gravity and the shaking component 6.

[0038] As attached Figure 4 As shown, the stirring mechanism 2 includes a motor 201, a stirring shaft 202, a first stirring rod 203, a second stirring rod 204, and a third stirring rod 205. The motor 201 is installed on the top cover 14, and the output end of the motor 201 is connected to the stirring shaft 202 rotatably connected to the top cover 14. Multiple groups of first stirring rods 203 are installed on the stirring shaft 202, and each group of first stirring rods 203 is internally connected to two second stirring rods 204. Each group of first stirring rods 203 is connected by multiple third stirring rods 205.

[0039] During specific implementation, the motor 201 is operated to drive the stirring shaft 202 to rotate, so that the first stirring rod 203 and the third stirring rod 205 stir the raw materials in the reaction tank 1, and the second stirring rod 204 is mainly used to stir the undulating raw materials when the reaction tank 1 is shaken to improve the stirring uniformity.

[0040] As attached Figure 5 As shown, the fixing assembly 4 includes a fixing bracket 401 and a fixing pressure plate 402, two fixing brackets 401 and two fixing pressure plates 402 are provided, the bottom ends of the two fixing brackets 401 are connected by a bottom plate 8, a fixing pressure plate 402 is installed on the top of each fixing bracket 401, and two fixing beams 17 are connected to the top of the two fixing brackets 401; The top end of the fixed bracket 401 and the bottom end of the fixed pressure plate 402 are both provided with a semicircular shaft groove and a semicircular groove. The fixed bracket 401 and the fixed pressure plate 402 are connected so that the two semicircular shaft grooves are connected to form an shaft hole, and the upper and lower connected semicircular grooves are connected to form a clamping groove. The shaft rod 12 is inserted into the shaft hole, and the shaft sleeve 13 is clamped in the clamping groove.

[0041] In specific implementation, the fixed brackets 401 on both sides are connected and fixed by the fixed beam 17, so as to provide stable support and fixation for the reaction tank 1. The top of the fixed bracket 401 and the bottom of the fixed pressure plate 402 are both provided with a semicircular shaft groove and a semicircular groove. When the fixed bracket 401 and the fixed pressure plate 402 are connected, the two semicircular shaft grooves are connected to form an axis hole, and the shaft rod 12 is inserted into the axis hole, so that the reaction tank 1 can rotate around the axis of the shaft rod 12 at a certain angle; the semicircular grooves connected up and down are connected to form a clamping groove, and the shaft sleeve 13 is clamped in the clamping groove to clamp the shaft The rod 12 plays a role in positioning and stabilizing. The semicircular shaft groove and semicircular groove are opened at the top of the fixed bracket 401 and the bottom of the fixed pressure plate 402. After the fixed bracket 401 and the fixed pressure plate 402 are connected, the semicircular shaft grooves are accurately connected to form an axis hole, and the shaft rod 12 is smoothly inserted into the axis hole, ensuring that the installation position of the reaction tank 1 is accurate and can rotate flexibly; the semicircular grooves are connected to form a clamping groove, and the sleeve 13 is stably clamped in the clamping groove to prevent the shaft rod 12 from shaking or shifting during movement, thereby ensuring that the reaction tank 1 can stably swing left and right with the shaft rod 12 as the axis.

[0042] As attached Figure 1 and Figure 2 As shown, a support plate 5 is welded to the inner side of each of the fixed brackets 401, and two of the support plates 5 respectively support a shaking assembly 6 connected to the support rod 301; The shaking assembly 6 includes a first hydraulic rod 601, a second hydraulic rod 602 and a base 603. One end of the first hydraulic rod 601 and the second hydraulic rod 602 are hinged on the support rod 301, and the other ends of the first hydraulic rod 601 and the second hydraulic rod 602 are respectively connected to two bases 603 installed on the support plate 5. The first hydraulic rod 601 and the second hydraulic rod 602 are both connected to a hydraulic pump.

[0043] In specific implementation, one end of the first hydraulic rod 601 and the second hydraulic rod 602 in the shaking assembly 6 are both hinged on the support rod 301, and the other ends are respectively connected to two bases 603 installed on the support plate 5. This hinged method enables the hydraulic rod to drive the reaction tank 1 to produce a shaking motion when it is extended and retracted, and the hydraulic pump controls the inflow and outflow of hydraulic oil to achieve the extension and retraction of the first hydraulic rod 601 and the second hydraulic rod 602. During stirring, the hydraulic rod is controlled to extend and retract at a certain frequency and amplitude to make the reaction tank 1 shake, and cooperate with the stirring mechanism 2 to achieve a better stirring effect; during discharging, the hydraulic rod is controlled to extend and retract to make the reaction tank 1 shake and tilt, so that the raw materials in the reaction tank 1 are thrown out from the discharge pipe due to the centrifugal effect, thereby improving the discharge efficiency and thoroughness of the discharge.

[0044] As attached Figure 2As shown, the guide assembly 7 includes a cross bar 701 and a guide frame 702, and two of the cross bar 701 and the guide frame 702 are provided. Both ends of the two cross bars 701 are connected to the fixed bracket 401. The guide frame 702 includes two arc frames and two connecting blocks. The two arc frames are arranged in parallel, and the two ends of the two arc frames are respectively connected to the corresponding connecting blocks, and each connecting block is respectively connected to the corresponding cross bar 701. An arc guide groove is formed between the two arc frames, and the pulley 302 is installed in the arc guide groove. The arc center of the arc guide groove coincides with the axis center line of the shaft 12.

[0045] During specific implementation, the two ends of the cross bar 701 are connected to the fixed bracket 401 to provide support for the guide frame 702. The guide frame 702 consists of two arc frames and two connecting blocks. The two arc frames are arranged in parallel and connected to the connecting blocks at both ends. The connecting blocks are further connected to the cross bar 701 to form a stable structure. An arc guide groove is formed between the two arc frames. The pulley 302 is installed in the arc guide groove, and the arc center of the arc guide groove coincides with the axis line of the shaft 12, so that when the reaction tank 1 moves, the pulley 302 rolls along the arc guide groove to ensure the accuracy of the movement trajectory of the reaction tank 1, so that the reaction tank 1 remains stable during shaking, stirring and discharging and tilting, and avoids excessive shaking or deviation from the predetermined trajectory.

[0046] As attached Figure 2 As shown, the positioning assembly 11 includes an electric push rod 1101 and a push plate 1102 , and one side of the push plate 1102 is connected to two electric push rods 1101 installed on a fixed bracket 401 .

[0047] In specific implementation, when the containing tank 9 has not moved onto the bottom plate 8, the two push plates 1102 and the bottom plate 8 form a guide channel, so that when the containing tank 9 moves onto the bottom plate 8, it can play a guiding role in the movement of the containing tank 9 to avoid deflection, and with the extension and retraction of the electric push rod 1101, the push plates 1102 on both sides can clamp and fix the containing tank 9, so that with the cooperation of the two sets of gratings 18, the containing tank 9 can be accurately positioned, thereby ensuring that the containing tank 9 is accurately placed at the predetermined position on the bottom plate 8, so as to accurately receive the clindamycin hydrochloride discharged from the reaction tank 1, and avoid vibration caused by shaking of the reaction tank 1 to cause the containing tank 9 to shift.

[0048] Finally, a few points should be explained: First, in the description of the present invention, it should be noted that, unless otherwise specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, which may refer to mechanical connection or electrical connection, or internal communication between two components, or direct connection. "upper", "lower", "left", "right", etc. are only used to indicate relative positional relationships. When the absolute position of the object being described changes, the relative positional relationship may change; Secondly: In the drawings of the embodiments disclosed in the present invention, only the structures related to the embodiments disclosed in the present invention are involved, and other structures can refer to the general design. In the absence of conflict, the same embodiment and different embodiments of the present invention can be combined with each other; Finally: The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A clindamycin hydrochloride reaction device, characterized in that: include: A reaction tank (1), wherein shaft rods (12) are welded on both sides of the top of the reaction tank (1), and each of the shaft rods (12) is sleeved with two shaft sleeves (13), and the two shaft rods (12) are commonly connected to a fixing component (4), and a bottom plate (8) is installed at the bottom of the fixing component (4), and ramp plates (10) are arranged on both sides of the bottom plate (8), and support components (3) are installed on both sides of the bottom end of the reaction tank (1), and the support component (3) comprises a support rod (301) and a pulley (302), and the pulley (302) is installed on the support rod (301); A stirring mechanism (2), wherein the stirring mechanism (2) is installed on the reaction tank (1); A guide assembly (7), the guide assembly (7) being mounted on the fixed assembly (4), the guide assembly (7) being connected and matched with two pulleys (302), and the guide assembly (7) being used to guide the pulleys (302); A shaking assembly (6), wherein two shaking assemblies (6) are provided, each of the shaking assemblies (6) is connected to a corresponding support rod (301), and the shaking assembly (6) is used to cooperate with the stirring mechanism (2) to shake and stir the reaction tank (1), and the shaking assembly (6) is also used to discharge materials from the reaction tank (1); A containing tank (9), the containing tank (9) being arranged on the bottom plate (8), the containing tank (9) being used to receive the produced clindamycin hydrochloride; Gratings (18), wherein two groups of gratings (18) are provided, one group of gratings (18) is installed at the front end of the inner side of the fixing component (4), and the other group of gratings (18) is installed at the rear end of the inner side of the fixing component (4), and the two groups of gratings (18) are used to detect the position of the containing groove (9) on the bottom plate (8); A positioning assembly (11), wherein two positioning assemblies (11) are provided, and each positioning assembly (11) is respectively provided on two sides of the containing groove (9), and the two positioning assemblies (11) are used to guide and clamp the containing groove (9) for positioning.

2. The clindamycin hydrochloride reaction device according to claim 1, characterized in that: A top cover (14) is installed on the top of the reaction tank (1), and a sealing ring (15) is provided between the top cover (14) and the reaction tank (1).

3. The clindamycin hydrochloride reaction device according to claim 2, characterized in that: The reaction tank (1) is provided with feeding ports (16) on both sides of the top, and each feeding port (16) is screwed with a sealing cover. The bottom of the reaction tank (1) is an arc-shaped structure, and a discharge pipe is installed at the bottom of the reaction tank (1), and a solenoid valve is installed on the discharge pipe.

4. The clindamycin hydrochloride reaction device according to claim 3, characterized in that: The stirring mechanism (2) comprises a motor (201), a stirring shaft (202), a first stirring rod (203), a second stirring rod (204), and a third stirring rod (205); the motor (201) is mounted on the top cover (14); an output end of the motor (201) is connected to a stirring shaft (202) rotatably connected to the top cover (14); a plurality of groups of first stirring rods (203) are mounted on the stirring shaft (202); each group of first stirring rods (203) is internally connected to two second stirring rods (204); and each group of first stirring rods (203) is connected via a plurality of third stirring rods (205).

5. The clindamycin hydrochloride reaction device according to claim 4, characterized in that: The fixing assembly (4) comprises a fixing bracket (401) and a fixing pressure plate (402), two fixing brackets (401) and two fixing pressure plates (402) are provided, the bottom ends of the two fixing brackets (401) are connected via a bottom plate (8), a fixing pressure plate (402) is installed at the top end of each fixing bracket (401), and two fixing beams (17) are connected to the top ends of the two fixing brackets (401).

6. The clindamycin hydrochloride reaction device according to claim 5, characterized in that: The top end of the fixed bracket (401) and the bottom end of the fixed pressure plate (402) are both provided with a semicircular shaft groove and a semicircular groove. The fixed bracket (401) and the fixed pressure plate (402) are connected so that the two semicircular shaft grooves are connected to form a shaft hole. The semicircular grooves connected up and down are connected to form a clamping groove. The shaft rod (12) is inserted into the shaft hole, and the shaft sleeve (13) is clamped in the clamping groove.

7. The clindamycin hydrochloride reaction device according to claim 6, characterized in that: A support plate (5) is welded to the inner side of each of the fixed brackets (401), and the two support plates (5) respectively support a shaking assembly (6) connected to the support rod (301).

8. The clindamycin hydrochloride reaction device according to claim 7, characterized in that: The shaking assembly (6) comprises a first hydraulic rod (601), a second hydraulic rod (602) and a base (603); one end of the first hydraulic rod (601) and the second hydraulic rod (602) are both hinged on the support rod (301); the other ends of the first hydraulic rod (601) and the second hydraulic rod (602) are respectively connected to two bases (603) installed on the support plate (5); and the first hydraulic rod (601) and the second hydraulic rod (602) are both connected to a hydraulic pump.

9. The clindamycin hydrochloride reaction device according to claim 8, characterized in that: The guide assembly (7) comprises a cross bar (701) and a guide frame (702), wherein two cross bars (701) and two guide frames (702) are provided, and both ends of the two cross bars (701) are connected to the fixed bracket (401). The guide frame (702) comprises two arc frames and two connecting blocks, and the two arc frames are arranged in parallel, and the two ends of the two arc frames are respectively connected to the corresponding connecting blocks, and each connecting block is respectively connected to the corresponding cross bar (701). An arc guide groove is formed between the two arc frames, and the pulley (302) is installed in the arc guide groove, and the arc center of the arc guide groove coincides with the axis center line of the shaft rod (12).

10. The clindamycin hydrochloride reaction device according to claim 9, characterized in that: The positioning assembly (11) comprises an electric push rod (1101) and a push plate (1102), and one side of the push plate (1102) is connected to two electric push rods (1101) mounted on a fixed bracket (401).

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