Stimulator waveform generating device and generating method

Abstract

The invention provides a stimulator waveform generation device and method. The stimulator waveform generation device comprises a power supply circuit and a waveform generation circuit. The waveform generation circuit periodically outputs pulse signals and comprises a control unit, a switching circuit and an output circuit. In each signal period, the output circuit outputs three positive pulses and a negative pulse in an equal-energy mode. Wherein the current amplitudes of the three forward pulses are gradually reduced, the current amplitude of the first forward pulse is smaller than a pain threshold value, a buffer interval is formed between every two adjacent forward pulses, and the duration of each buffer interval is in negative correlation with the effective current amplitude of the previous forward pulse; the negative pulse is located behind the last positive pulse in an equal-energy mode; the equal energy means that the products of the current effective amplitude of each pulse and the corresponding pulse stimulation duration are the same.

Description

Technical Field

[0001] The present invention relates to the technical field of electrotherapy, and in particular to a stimulator waveform generating device and a generating method. Background Art

[0002] As a non-invasive treatment strategy, transcutaneous vagus nerve stimulation (tVNS) has shown wide application potential in the treatment of depression, anxiety, epilepsy, pain management and other diseases by stimulating the vagus nerve at specific body surface locations. Existing vagus nerve stimulation devices generally output in the form of fixed waveforms and fixed waveform parameters (including waveform amplitude and interval). However, due to various factors such as the physical and psychological factors of different stimulation objects, there are certain differences in the heart rate variability reflected by different stimulation objects under the same stimulation parameters. Therefore, when targeting different stimulation objects, vagus nerve stimulation devices based on fixed waveform parameters are prone to the fact that the stimulation effect of some objects is difficult to achieve the expected effect, while some objects cannot tolerate the fixed stimulation intensity and experience side effects such as pain and discomfort.

[0003] To solve this problem, there are currently vagus nerve adaptive adjustment devices on the market that can adaptively adjust the stimulation waveform according to the response of the stimulation object. The device adaptively adjusts the stimulation waveform and / or waveform parameters by continuously collecting the heart rate variability of the stimulation object. However, in actual applications, due to the interference of factors such as heart rate collection accuracy, signal transmission delay, and algorithm compatibility, the adaptive adjustment ability of the stimulation waveform parameters is poor, and the stimulation effect has not been greatly improved compared to traditional fixed waveform stimulation devices. However, the adaptive output of the stimulation waveform greatly increases the complexity of the circuit and control program, and the complex adaptive algorithm also makes the price of this type of equipment extremely high. Summary of the invention

[0004] In order to overcome the deficiencies of the prior art, the present invention provides a stimulator waveform generating device and a generating method which can adjust waveform parameters based on a user input gear.

[0005] In order to achieve the above-mentioned purpose, the present invention provides a stimulator waveform generating device, which includes a power supply circuit and a waveform generating circuit. The waveform generating circuit periodically outputs a pulse signal and includes a control unit, a switching circuit and an output circuit; in each signal cycle, the output circuit outputs three positive pulses and one negative pulse in an equal energy manner. Among them, the current amplitudes of the three positive pulses gradually decrease and the current amplitude of the first positive pulse is less than the pain threshold, a buffer interval is formed between two adjacent positive pulses and the duration of each buffer interval is negatively correlated with the effective current amplitude of the previous positive pulse; the negative pulse is located after the last positive pulse in an equal energy manner; equal energy means that the product of the effective current amplitude of each pulse and the corresponding pulse stimulation duration is the same.

[0006] According to an embodiment of the present invention, in each signal cycle, the output circuit sequentially outputs three positive rectangular pulses and one negative rectangular pulse in a constant current mode.

[0007] According to an embodiment of the present invention, a commutation interval is formed between the third positive pulse and the negative pulse, and the effective amplitude of the current in the commutation interval is greater than or equal to zero.

[0008] According to an embodiment of the present invention, the effective amplitudes of the currents in the buffer interval and the commutation interval are both greater than zero, and the output circuit outputs each buffer interval and commutation interval in an equal energy manner.

[0009] According to an embodiment of the present invention, the duration of each buffer interval is negatively correlated with the effective current amplitude of the previous positive pulse, and the duration of the commutation interval is negatively correlated with the effective current amplitude of the third positive pulse.

[0010] According to an embodiment of the present invention, the effective current amplitude of the negative pulse is smaller than the effective current amplitude of the third positive pulse, and the current amplitudes of the three positive pulses and the negative pulse decay in an exponential form.

[0011] On the other hand, the present invention also provides a waveform generating method of a stimulator waveform generating device, comprising:

[0012] Based on the stimulation level Level and the reference stimulation intensity amp input by the user, the amplitude factor H of the pulse signal is obtained, and the amplitude factor is exponentially attenuated according to the preset attenuation factor α to obtain the effective current amplitude of three positive pulses and one negative pulse;

[0013] The pulse energy is determined based on the amplitude factor H and the stimulation frequency freq selected by the user;

[0014] Based on equal energy output, the stimulation duration of each pulse is calculated after determining the pulse energy and the effective current amplitude of each pulse;

[0015] Determine the buffer interval duration between adjacent forward pulses according to the relationship between the preset buffer interval duration and the effective amplitude of the previous forward pulse current;

[0016] Based on the determined current effective amplitude, pulse stimulation duration and buffer interval duration of each positive pulse, three interval-distributed equal-energy positive pulses are output in sequence, and an equal-energy negative pulse is output after the third positive pulse.

[0017] According to an embodiment of the present invention, a commutation interval is output between the third positive pulse and the negative pulse, and the effective amplitude of the current in the buffer interval and the commutation interval is greater than or equal to zero.

[0018] According to one embodiment of the present invention, the duration of each buffer interval is negatively correlated with the effective current amplitude of the previous positive pulse, and the duration of the commutation interval is negatively correlated with the effective current amplitude of the third positive pulse; after obtaining the effective current amplitude of each positive pulse, the duration of the corresponding buffer interval or the commutation interval is determined.

[0019] According to an embodiment of the present invention, after the duration of the buffer interval and the duration of the commutation interval are determined, the effective current amplitude of each buffer interval and the effective current amplitude of the commutation interval are determined based on the equal energy output mode.

[0020] In summary, the stimulator waveform generating device and generating method provided by the present invention output multiple pulses with decreasing current effective amplitudes and spaced distribution in each signal cycle through an equal energy mode. The equal energy output mode makes the stimulation duration of each pulse change with the effective amplitude of the pulse current, and the effective current amplitude and pulse energy of the pulse are related to the user-set parameters, that is, the pulse parameters are dynamically regulated according to the user's settings. Such a control method allows different users to select different waveform parameters, and improve the stimulation effect within their tolerance range to meet the needs of different users. Furthermore, multiple positive pulse waveforms with the effective amplitude of the current decaying in sequence can effectively activate and continuously stimulate the vagus nerve without causing pain to the user, so as to accumulate the stimulation effect. The buffer interval whose duration is automatically adjusted with the effective amplitude of the previous positive pulse current can adjust the stimulation accumulation to avoid excessive stimulation and excessive excitement of nerve fibers; in addition, the buffer interval can also reduce the distortion or interference of the pulse signal to improve the signal output quality. The setting of the negative low level can neutralize the accumulated charge, prevent the accumulation of charge from causing damage to the user, and ensure the safety of the stimulation process.

[0021] In order to make the above and other purposes, features and advantages of the present invention more obvious and easy to understand, preferred embodiments are given below and described in detail with reference to the accompanying drawings. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 The figure shows a principle block diagram of a stimulator waveform generating device provided in one embodiment of the present invention.

[0023] Figure 2 Shown Figure 1 The waveform diagram of the output of the stimulator waveform generating device is shown.

[0024] Figure 3 The figure is a flow chart of a waveform generating method of a stimulator waveform generating device provided in one embodiment of the present invention. DETAILED DESCRIPTION

[0025] Traditional vagus nerve stimulation devices with fixed waveform output are difficult to meet the stimulation needs of different subjects due to the fixed waveform parameters. Stimulation devices with adaptive waveform adjustment are affected by factors such as signal acquisition accuracy and transmission delay, making it difficult to effectively improve the stimulation effect; in addition, such devices also have problems such as complex operation and high prices. In view of this, the present embodiment provides a stimulator waveform generating device that can automatically adjust the waveform based on user input parameters; the waveform generating device not only has the advantages of rapid waveform parameter adjustment response and high stimulation accuracy, but also has the advantages of simple circuit structure and control.

[0026] like Figure 1 and Figure 2 As shown, the stimulator waveform generating device provided in this embodiment includes a power supply circuit 10 and a waveform generating circuit 20. The waveform generating circuit 20 periodically outputs a pulse signal and includes a control unit 1, a switching circuit 2 and an output circuit 3. In each signal cycle, the output circuit 3 outputs three positive pulses and one negative pulse in an equal energy manner. Among them, the current amplitude (i.e., the stimulation intensity) of the three positive pulses gradually decreases and the current amplitude of the first positive pulse is less than the pain threshold. A buffer interval is formed between two adjacent positive pulses and the duration of each buffer interval is negatively correlated with the effective current amplitude of the previous positive pulse; the negative pulse is located after the last positive pulse in an equal energy manner. Equal energy means that the product of the effective current amplitude of each pulse and the corresponding pulse stimulation duration is the same.

[0027] like Figure 2 As shown in FIG. 1 , in each signal cycle, the effective current amplitude of the first positive pulse is hc1, and its stimulation duration is tc1; the effective current amplitude of the second positive pulse is hc2, and its stimulation duration is tc2; the effective current amplitude of the third positive pulse is hc3, and its stimulation duration is tc3. The output circuit 3 outputs three positive pulses in an equal energy manner, that is, each pulse has an energy of .

[0028] The stimulator waveform generating device provided in this embodiment produces continuous stimulation to the user by outputting three positive pulses in each signal cycle, and the cumulative stimulation effect is used to improve the stimulation effect. Specifically, the effective current amplitude of the first pulse is hc3, which is higher than the sensory threshold, but lower than the pain threshold to activate the neurotransmitters of the vagus nerve, and the pain threshold is usually less than or equal to 80mA. The second pulse continues to stimulate the vagus nerve after activation so that it continues to release neurotransmitters within the tc2 time period. The effective current amplitude of the third pulse is lower than the sensory threshold, which reduces the stimulation intensity, and continuously stimulates the released neurotransmitters to promote their transfer, thereby achieving the cumulative effect of electrical stimulation.

[0029] The equal energy pulse signal provided in this embodiment enables the first positive pulse to quickly activate the vagus nerve with a high current effective amplitude hc1 (i.e., the stimulation time tc1 is very short). After the vagus nerve is activated, the second pulse prolongs the stimulation time (tc2>tc1) by reducing the effective amplitude of the stimulation current (hc2<hc1) so that the vagus nerve releases neurotransmitters for a long time, providing conditions for the stimulation accumulation of the third positive pulse, so that the generated neurotransmitters can be promoted and transferred under the stimulation of the third pulse of low intensity, thereby achieving a better stimulation effect. Further, a negative pulse is output after three positive pulses, and negative charges are used to neutralize the charges accumulated after the stimulation of the three positive pulses to avoid the accumulation of charges under the body surface and causing damage to the user. Specifically, the current effective amplitude hc4 of the negative pulse is less than the current effective amplitude hc3 of the third positive pulse, and the current effective amplitudes of the three positive pulses and one negative pulse gradually decay in an exponential form. However, the present invention does not make any limitation to this. In other embodiments, the current effective amplitudes of the four pulses can also decay in a linear manner.

[0030] In this embodiment, the output circuit 3 sequentially outputs three positive rectangular pulses and one negative rectangular pulse in a constant current mode in each signal cycle. The maximum amplitude of each positive rectangular pulse is its current effective amplitude, and the maximum amplitude of the negative rectangular pulse is its current effective amplitude. The rectangular pulse can increase the stimulation duration of each pulse at the current effective amplitude, and improve the stimulation effect within a limited stimulation duration. However, the present invention does not make any limitation to this. In other embodiments, the three positive pulses and the negative pulse may also be sinusoidal pulses.

[0031] like Figure 2 As shown, in the waveform generated by the stimulator waveform generating device provided in this embodiment, a buffer interval is also formed between two adjacent positive pulses. Specifically, a first buffer interval is formed between the first positive pulse and the second positive pulse, and its current effective amplitude is hj1 and its interval duration is tj1; and a second buffer interval is formed between the second positive pulse and the third positive pulse, and its current effective amplitude is hj2 and its interval duration is tj2. The setting of the first buffer interval and the second buffer interval can compensate for the signal loss caused by factors such as the transmission path and device response, reduce the distortion or interference of the pulse signal, and thus improve the quality of the overall signal; at the same time, the setting of the buffer interval can also dynamically adjust the stimulation intensity and stimulation duration between adjacent positive pulses, thereby reducing the user's pain and fatigue so that sensitive users can better tolerate the stimulation of each positive pulse, thereby being well compatible with users with different somatosensory reactions. Furthermore, in this embodiment, a switching interval is formed between the third positive pulse and the negative pulse; similarly, the switching interval can effectively reduce signal distortion and interference when the output circuit switches from a positive pulse to a negative pulse and reduce the user's stimulation response to the switching between positive and negative pulses.

[0032] In this embodiment, the effective current amplitudes of the first buffer interval, the second buffer interval, and the commutation interval are all greater than zero, and the output circuit 3 outputs each buffer interval and commutation interval in an equal energy manner; and the duration of each buffer interval is negatively correlated with the effective current amplitude of the previous positive pulse, and the duration of the commutation interval is negatively correlated with the effective current amplitude of the third positive pulse. That is, in the stimulator waveform generating device provided in this embodiment, the stimulation intensity of each positive pulse is inversely proportional to the interval duration after the positive pulse. This setting makes it possible that: for users with strong stimulation tolerance, when they choose high-intensity stimulation (i.e., high effective amplitude of stimulation current and high stimulation frequency), the duration of the buffer interval (or commutation interval) is shortened to enhance the stimulation effect; and for users with weak tolerance, when they choose low-intensity, long-term stimulation gears to ensure equal stimulation energy, a longer buffer interval (or commutation interval) is provided to dynamically reduce the pain and fatigue of such users after a long period of stimulation. The interval durations matched with different stimulation intensities enable the stimulator waveform generating device provided in this embodiment to better meet the needs of different somatosensory users.

[0033] In the stimulator waveform generating device provided in the present embodiment, the power supply circuit 10 includes a boost circuit to increase the input power supply voltage. The control unit 1 is an MCU, which determines the amplitude factor H and the pulse energy E related to the effective amplitude of the pulse current based on the stimulation gear Level and the stimulation frequency freq selected by the user. The switch circuit 2 is a PWM switch commutation circuit electrically connected to the control unit 1, which is closed / disconnected and commutated based on the PWM signal output by the control unit 1, thereby realizing the output of three positive pulses, two buffer intervals, a commutation interval and a negative pulse in each signal cycle, and the output of the tc5 stage with zero amplitude between adjacent signal cycles. As for the output circuit 3, in the present embodiment, it outputs three positive rectangular pulses and one negative rectangular pulse in a constant current mode, which can be an integrated constant current source module or an existing constant current circuit composed of semiconductor devices. The present invention does not make any limitation on the specific structure of the circuit.

[0034] Corresponding to the above-mentioned stimulator waveform generating device, this embodiment provides a waveform generating method of the stimulator waveform generating device, the method comprising:

[0035] Step S10, based on the stimulation level Level and the reference stimulation intensity amp input by the user, the amplitude factor H of the pulse signal is obtained, and the amplitude factor H is exponentially attenuated according to the preset attenuation factor α to obtain the effective current amplitudes hc1, hc2, hc3 of three positive pulses and the effective current amplitude hc3 of a negative pulse. Specifically, Level is the stimulation intensity level set by the user, and its range is [1, N] and the step is 1, N is generally 20, indicating 20 levels; the reference stimulation intensity amp is generally 4mA. When the user selects the stimulation level Level, the control unit 1 in the waveform generating circuit 20 will calculate the amplitude factor H according to the following formula:

[0036] ;

[0037] After the amplitude factor H is obtained, exponential decay is performed based on the amplitude factor H with a preset attenuation factor α, thereby obtaining the effective amplitude of each pulse: , , , . Preferably, the attenuation factor α is set to 0.5. However, the present invention does not impose any limitation on this. In other embodiments, the attenuation factor α may also be 0.2, 0.25 or other values ​​within the range of 0 to 1. In other embodiments, a linear manner may be adopted to attenuate or increase the amplitude factor H to form three positive pulses with decreasing current effective amplitudes.

[0038] Step S20: The control unit 1 determines the pulse energy E according to the amplitude factor H calculated in step S10 and the stimulation frequency freq selected by the user:

[0039] ;

[0040] Step S30: After determining the pulse energy E, the control unit 1 controls the output of three positive pulses and a negative pulse in an equal amount mode. After determining the effective current amplitude of each pulse in step S10 and the pulse energy E in step S20, the control unit 1 obtains the stimulation duration of each pulse , , , , the unit of stimulation duration is us.

[0041] In the waveform generation method provided in this embodiment, steps S10 to S30 determine the parameters of three positive pulses and one negative pulse in each signal cycle. As described above, in the waveform generated by the stimulator waveform generation device provided in this embodiment, a buffer interval is formed between adjacent positive pulses, and a commutation interval is also formed between the last positive pulse and the negative pulse, so it is necessary to determine the specific parameters of the two buffer intervals and the commutation interval.

[0042] In this embodiment, the duration of each buffer interval is negatively correlated with the effective current amplitude of the previous positive pulse, and the duration of the commutation interval is negatively correlated with the effective current amplitude of the third positive pulse. Therefore, after obtaining the effective current amplitude of each positive pulse, the duration of the subsequent buffer interval or the duration of the commutation interval is determined (step S40). Specifically, the product of the duration of each buffer interval and the effective current amplitude of the previous positive pulse is set to an interval energy parameter K related to the stimulation frequency freq, that is, . Wherein, tj1 is the duration of the first buffer interval, hc1 is the effective current amplitude of the first positive pulse, tj2 is the duration of the second buffer interval, hc2 is the effective current amplitude of the first positive pulse, tj3 is the duration of the commutation interval, and hc3 is the effective current amplitude of the third positive pulse. Specifically, the interval energy parameter K is related to the stimulation frequency freq and decreases with the increase of the frequency freq; the larger the stimulation frequency freq selected by the user, the stronger the stimulation tolerance of the user. At this time, the buffer interval duration and the commutation interval duration can be shortened (that is, the interval energy parameter K can be reduced) to enhance the stimulation effect. On the contrary, for users with weaker stimulation tolerance, the selected stimulation frequency freq is smaller, and the pain and fatigue caused by the stimulation can be reduced by extending the buffer interval duration and the commutation interval duration.

[0043] Preferably, the interval energy parameter K is set to a segmented value based on the stimulation frequency. Specifically, when the stimulation frequency freq is between 0 and 200 Hz, K=5; when the stimulation frequency freq is between 201 and 400 Hz, K=4; when the stimulation frequency freq is between 401 and 600 Hz, K=3; when the stimulation frequency freq is between 601 and 800 Hz, K=2; when the stimulation frequency freq is between 801 and 1000 Hz, K=1. However, the present invention does not impose any limitation on this. In other embodiments, the buffer interval can also be set to a fixed interval duration.

[0044] In this embodiment, the effective current amplitudes of the two buffer intervals and the effective current amplitude of the commutation interval are both greater than zero. To achieve dynamic adjustment of the buffer amplitude, the output circuit 3 outputs each buffer interval and commutation interval in an equal energy manner. , preferably β is 0.1. After determining the buffer interval duration tj1, tj2 and the commutation interval duration tj3 in step S40, the equal interval energy output will determine the current effective amplitude hj1, hj2 of each buffer interval and the current effective amplitude hj3 of the commutation interval. However, the present invention is not limited to this. In other embodiments, the amplitudes of the buffer interval and the commutation interval may also be zero.

[0045] At this point, the parameters of the three positive pulses, two buffer intervals, the commutation interval, and the negative pulse have been determined. Execute step S50, based on the determined current effective amplitude of each positive pulse, the pulse stimulation duration, and the buffer interval duration, output three equal-energy positive pulses distributed at intervals in sequence, and output a negative pulse of equal energy after the third positive pulse, thereby achieving Figure 2 Output of the stimulus waveform.

[0046] In this embodiment, the output circuit 3 is a constant current control circuit, which outputs three positive rectangular pulses, two rectangular buffer intervals, a rectangular commutation interval, and a rectangular negative pulse in a constant current mode. However, the present invention is not limited to this. In other embodiments, the three positive pulses, the two buffer intervals, the commutation interval, and the negative pulse can all be sinusoidal pulses.

[0047] In this embodiment, when the user selects , After that, the control unit 1 obtains the amplitude factor ; Further, the pulse energy is obtained . Then, based on the attenuation factor Attenuation is performed to determine the effective current amplitudes of the three positive pulses and the negative pulse and the corresponding stimulation duration; specifically, , , , Then in step S40, based on the interval energy parameter K and interval energy β*K=0.5 respectively determine the effective current amplitude and interval duration of the two buffer intervals, as well as the effective current amplitude and interval duration of the commutation interval; specifically, , .

[0048] The specific parameters of the effective current amplitude of each pulse in the stimulation waveform output by this embodiment, the stimulation duration, the interval duration between adjacent pulses, and the effective current amplitude in the interval are shown in Table 1:

[0049] Table 1

[0050]

[0051] However, the present invention does not impose any limitation on this. In other embodiments, it is also possible to set , , , , , , , Correspondingly, specific parameters of the effective current amplitude of each pulse in the stimulation waveform output by other embodiments, the stimulation duration, the interval duration between adjacent pulses, and the effective current amplitude in the interval are shown in Table 2.

[0052] Table 2

[0053]

[0054] Alternatively, in other embodiments, set , , , , , , , Correspondingly, specific parameters of the effective current amplitude of each pulse in the stimulation waveform output by another embodiment, the stimulation duration, the interval duration between adjacent pulses, and the effective current amplitude in the interval are shown in Table 3.

[0055] Table 3

[0056]

[0057] In summary, the stimulator waveform generating device and generating method provided by the present invention output multiple pulses with decreasing current effective amplitudes and spaced distribution in each signal cycle through an equal energy mode. The equal energy output mode makes the stimulation duration of each pulse change with the effective amplitude of the pulse current, and the effective current amplitude and pulse energy of the pulse are related to the user-set parameters, that is, the pulse parameters are dynamically regulated according to the user's settings. Such a control method allows different users to select different waveform parameters, and improve the stimulation effect within their tolerance range to meet the needs of different users. Furthermore, multiple positive pulse waveforms with the effective amplitude of the current decaying in sequence can effectively activate and continuously stimulate the vagus nerve without causing pain to the user, so as to accumulate the stimulation effect. The buffer interval whose duration is automatically adjusted with the effective amplitude of the previous positive pulse current can adjust the stimulation accumulation to avoid excessive stimulation and excessive excitement of nerve fibers; in addition, the buffer interval can also reduce the distortion or interference of the pulse signal to improve the signal output quality. The setting of the negative low level can neutralize the accumulated charge, prevent the accumulation of charge from causing damage to the user, and ensure the safety of the stimulation process.

[0058] Although the present invention has been disclosed as above by the preferred embodiment, it is not intended to limit the present invention. Anyone familiar with this technology can make slight changes and modifications without departing from the spirit and scope of the present invention. Therefore, the scope of protection of the present invention shall be based on the scope of protection required by the claims.

Claims

1. A stimulator waveform generating device, characterized in that: It includes a power supply circuit and a waveform generating circuit, the waveform generating circuit periodically outputs a pulse signal and includes a control unit, a switch circuit and an output circuit; in each signal cycle, the output circuit outputs three positive pulses and one negative pulse in an equal energy manner; Among them, the current amplitudes of the three positive pulses gradually decrease and the current amplitude of the first positive pulse is less than the pain threshold, a buffer interval is formed between two adjacent positive pulses and the duration of each buffer interval is negatively correlated with the effective current amplitude of the previous positive pulse; the negative pulse is located after the last positive pulse in an equal energy manner; the equal energy means that the product of the effective current amplitude of each pulse and the corresponding pulse stimulation duration is the same.

2. The stimulator waveform generating device according to claim 1, characterized in that: In each signal cycle, the output circuit sequentially outputs three positive rectangular pulses and one negative rectangular pulse in a constant current mode.

3. The stimulator waveform generating device according to claim 1, characterized in that: A commutation interval is formed between the third positive pulse and the negative pulse, and the effective amplitude of the current in the commutation interval is greater than or equal to zero.

4. The stimulator waveform generating device according to claim 3, characterized in that: The effective amplitudes of the currents in the buffer interval and the commutation interval are both greater than zero, and the output circuit outputs each buffer interval and commutation interval in an equal energy manner.

5. The stimulator waveform generating device according to claim 3, characterized in that: The duration of each buffer interval is negatively correlated with the effective current amplitude of the previous positive pulse, and the duration of the commutation interval is negatively correlated with the effective current amplitude of the third positive pulse.

6. The stimulator waveform generating device according to claim 1, characterized in that: The effective current amplitude of the negative pulse is smaller than the effective current amplitude of the third positive pulse, and the current amplitudes of the three positive pulses and the negative pulse decay in an exponential form.

7. A waveform generating method of a stimulator waveform generating device, characterized in that: include: Based on the stimulation level Level and the reference stimulation intensity amp input by the user, the amplitude factor H of the pulse signal is obtained, and the amplitude factor is exponentially attenuated according to the preset attenuation factor α to obtain the effective current amplitude of three positive pulses and one negative pulse; The pulse energy is determined based on the amplitude factor H and the stimulation frequency freq selected by the user; Based on equal energy output, the stimulation duration of each pulse is calculated after determining the pulse energy and the effective current amplitude of each pulse; Determine the buffer interval duration between adjacent forward pulses according to the relationship between the preset buffer interval duration and the effective amplitude of the previous forward pulse current; Based on the determined current effective amplitude, pulse stimulation duration and buffer interval duration of each positive pulse, three interval-distributed equal-energy positive pulses are output in sequence, and an equal-energy negative pulse is output after the third positive pulse.

8. The waveform generating method of the stimulator waveform generating device according to claim 7, characterized in that: A commutation interval is output between the third positive pulse and the negative pulse, and the effective amplitudes of the currents in the buffer interval and the commutation interval are both greater than or equal to zero.

9. The waveform generating method of the stimulator waveform generating device according to claim 8, characterized in that: The duration of each buffer interval is negatively correlated with the effective current amplitude of the previous positive pulse, and the duration of the commutation interval is negatively correlated with the effective current amplitude of the third positive pulse; After obtaining the effective current amplitude of each forward pulse, the duration of the corresponding buffer interval or the duration of the commutation interval is determined.

10. The waveform generating method of the stimulator waveform generating device according to claim 9, characterized in that: After determining the duration of the buffer interval and the duration of the commutation interval, the effective current amplitude of each buffer interval and the effective current amplitude of the commutation interval are determined based on the equal energy output mode.

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