Ablation control method, system and device, computer equipment and storage medium

Abstract

The invention relates to an ablation control method, system and device, computer equipment, a computer readable storage medium and a computer program product. The method comprises the steps that under the condition that an ablation area is determined, an ablation signal is provided for a target electrode so as to apply ablation energy to the ablation area; acquiring physiological parameters in the process of providing the ablation signal to the target electrode; according to the change trend of the physiological parameters and a preset reference threshold value, ablation categories corresponding to the ablation area are determined, and the ablation categories comprise recommended ablation categories and non-ablation categories; and under the condition that the ablation category is determined to be the recommended ablation category, continuing to provide the ablation signal to the target electrode to ablate the ablation region. On one hand, the ablation effect is monitored, it is guaranteed that the ablation effect reaches the standard, on the other hand, damage to an acting object caused by excessive ablation or wrong ablation positions is avoided, and the ablation safety is improved.

Description

Technical Field

[0001] The present application relates to the field of medical technology, and in particular to an ablation control method, system, device, computer equipment, computer-readable storage medium, and computer program product. Background Art

[0002] With the development of medical technology, minimally invasive ablation technology has emerged. By making a small incision in the epidermis of the subject, the electrode needle is inserted into the subject's body to reach the location of the subject's lesion tissue, and then the high-voltage pulse generated between the electrodes is used to ablate the subject's lesion tissue, thereby achieving the purpose of removing the subject's lesion tissue. Pulmonary hypertension (PH) refers to a clinical and pathophysiological syndrome caused by changes in pulmonary vascular structure or function due to a variety of heterogeneous diseases (causes) and different pathogenesis, resulting in increased pulmonary vascular resistance and pulmonary artery pressure, which then develops into right heart failure or even death. At present, the treatment of pulmonary hypertension revolves around three major pathways related to endothelial dysfunction responsible for pulmonary artery remodeling. This includes inhibiting vasoconstrictors and activating major vasodilators such as nitric oxide and prostacyclin. Despite the widespread use of pulmonary hypertension-specific treatments, the mortality rate of patients remains high, accounting for about 10% of patients each year, and the 5-year survival rate is still unacceptably low (59.4%). Studies have shown that increased sympathetic nerve activity is related to the pathogenesis of pulmonary hypertension. Rudner et al. reported that sympathetic nerves exist in the pulmonary artery wall and participate in the regulation of pulmonary artery pressure, suggesting that perivascular nerves are potential targets for interventional therapy. Therefore, pulmonary artery dialysis (PADN) has been proposed as a method to reduce pulmonary artery pressure. Some people have already practiced this method in animals and humans. In these studies, a decrease in pulmonary artery pressure was recorded after circular ablation of the pulmonary artery bifurcation and the proximal part of the left and right main pulmonary arteries. Published clinical studies have shown that pulmonary artery pressure is significantly reduced after non-selective circular pulmonary artery ablation. Non-selective circular pulmonary artery ablation is blind ablation, which ignores the distribution of sympathetic nerves on the pulmonary artery adventitia, which may further lead to pulmonary artery fibrosis remodeling and loss of pulmonary artery expansion capacity, which is associated with the further development of pulmonary hypertension and death. In response to this problem, some people have proposed that pulmonary artery stimulation mapping of ablation targets may be a safer and more reasonable approach.

[0003] However, because doctors in traditional technology rely on their own experience to operate electrodes to perform ablation surgery on the target lesion tissue, whether it is non-selective circular ablation of the pulmonary artery (blind ablation) or stimulation of the mapping target for ablation, the treatment effect can often only be followed up, and it is impossible to know in real time whether the ablation has killed the sympathetic nerves. The decrease in impedance during ablation can only prove that the vascular epithelial cells have been killed, but the nerves are often buried deep, and the decrease in impedance cannot be used to determine whether the nerves have been killed. In other words, during the ablation process, it is impossible to determine whether the sympathetic nerves at the ablation point have been killed. Once there are too many ineffective ablations, it will directly affect the surgical effect, and postoperative recurrence is also prone to occur. Therefore, there may be incomplete ablation or ablation failure. How to intuitively judge whether the sympathetic nerves at the ablation point exist and have been killed, and then determine whether ablation needs to continue to improve the surgical effect, is a problem that needs to be solved at present. Summary of the invention

[0004] Based on this, it is necessary to provide an ablation control method, system, device, computer equipment, computer-readable storage medium, and computer program product that can detect the ablation situation and accurately determine whether ablation needs to be continued, thereby improving the ablation effect.

[0005] An ablation control method comprises: when an ablation area is determined, providing an ablation signal to a target electrode to apply ablation energy to the ablation area; in the process of providing the ablation signal to the target electrode, acquiring physiological parameters; wherein the physiological parameters are physiological parameters of an object of the target electrode under the action of the ablation signal; according to a change trend of the physiological parameters and a preset reference threshold, determining an ablation category corresponding to the ablation area, wherein the ablation category includes a recommended ablation category and a no-ablation category; when it is determined that the ablation category is the recommended ablation category, continuing to provide an ablation signal to the target electrode to ablate the ablation area.

[0006] In one of the embodiments, determining whether to continue to provide an ablation signal to the target electrode to ablate the ablation area based on the changing trend of the physiological parameter and a preset benchmark threshold includes: determining the ablation category corresponding to the ablation area based on the changing trend of the physiological parameter and a preset benchmark threshold, wherein the ablation category includes a recommended ablation category and a no-ablation category; and when it is determined that the ablation category is the recommended ablation category, continuing to provide an ablation signal to the target electrode to ablate the ablation area.

[0007] In one embodiment, the physiological parameter includes a heart rate value, the preset benchmark threshold includes a heart rate benchmark threshold, and determining the ablation category corresponding to the ablation area according to the change trend of the physiological parameter and the preset benchmark threshold includes: when the change trend of the heart rate value satisfies a first preset heart rate condition, determining that the ablation category corresponding to the ablation area is the recommended ablation category; wherein the first preset heart rate condition includes: the heart rate value shows a continuous increasing trend, and the heart rate values ​​within a set time period are all greater than the heart rate benchmark threshold, or the heart rate value shows a continuous decreasing trend, and the heart rate values ​​within a set time period are all less than the heart rate benchmark threshold.

[0008] In one embodiment, the category not requiring ablation includes a first subcategory and a second subcategory; determining the ablation category corresponding to the ablation area according to the changing trend of the heart rate value and the heart rate reference threshold includes: when the changing trend of the heart rate value satisfies the second preset heart rate condition, determining that the ablation category corresponding to the ablation area is the first subcategory; wherein the second preset heart rate condition includes: the absolute value of the rate of change of the heart rate value relative to the heart rate reference threshold is less than a set threshold; when the changing trend of the heart rate value satisfies the third preset heart rate condition, determining that the ablation category corresponding to the ablation area is the second subcategory; wherein the third preset heart rate condition includes: the heart rate value first shows an upward trend and rises to above the heart rate reference threshold, and then shows a downward trend and falls to below or equal to the heart rate reference threshold, or the heart rate value first shows a downward trend and falls to below the heart rate reference threshold, and then shows an upward trend and rises to above or equal to the heart rate reference threshold.

[0009] In one embodiment, the physiological parameter includes a blood pressure value, the preset benchmark threshold includes a blood pressure benchmark threshold, and determining the ablation category corresponding to the ablation area based on the change trend of the physiological parameter and the preset benchmark threshold includes: when the change trend of the blood pressure value satisfies a first preset blood pressure condition, determining that the ablation category corresponding to the ablation area is a recommended ablation category; wherein the first preset blood pressure condition includes: the blood pressure value shows a continuous increasing trend, and the blood pressure values ​​within a set time period are all greater than the blood pressure benchmark threshold; or, the blood pressure value first shows a decreasing trend and then an increasing trend, and the blood pressure values ​​within a set time period are all greater than the blood pressure benchmark threshold.

[0010] In one embodiment, the category of no ablation required includes a first subcategory and a second subcategory; determining the ablation category corresponding to the ablation area based on the changing trend of the blood pressure value and the blood pressure reference threshold includes: when the changing trend of the blood pressure value satisfies a second preset blood pressure condition, determining that the ablation category corresponding to the ablation area is the second subcategory; wherein, the second preset blood pressure condition includes: the blood pressure value first shows an upward trend, and rises to above the blood pressure reference threshold, and then shows a downward trend, and drops to below or equal to the blood pressure reference threshold.

[0011] In one of the embodiments, determining the ablation category corresponding to the ablation area based on the changing trend of the blood pressure value and the blood pressure baseline threshold value also includes: when it is determined that the ablation category corresponding to the ablation area is not the recommended ablation category and is not the second subcategory, determining that the ablation category corresponding to the ablation area is the first subcategory.

[0012] In one embodiment, the ablation control method further includes: when determining that the ablation category is a recommended ablation category, continuing to provide the ablation signal to the target electrode according to a preset strategy, wherein the preset strategy is: extending the time of providing the ablation signal to the target electrode, and / or increasing the power of the ablation signal provided to the target electrode.

[0013] In one of the embodiments, the ablation control method further includes: when it is determined that the ablation category is the first subcategory, reconfirming a new ablation area within a preset range around the target electrode.

[0014] In one embodiment, the ablation control method further includes: after reconfirming the new ablation area, using the electrode corresponding to the new ablation area as a new target electrode, providing an ablation signal to the new target electrode, so as to apply ablation energy to the new ablation area.

[0015] An ablation system, comprising:

[0016] An electrode assembly, comprising a catheter and a plurality of electrodes spaced apart on the catheter;

[0017] an ablation module, connected to the plurality of electrodes respectively, and used for providing an ablation signal to each of the electrodes, wherein the ablation signal is used for ablating the sympathetic nerves of the pulmonary artery;

[0018] A collection module, used for collecting physiological parameters of the subject to which the multiple electrodes act;

[0019] A control module is connected to the ablation module and the acquisition module respectively, and is used to control the ablation module to provide an ablation signal to the target electrode when the ablation area is determined, so as to apply ablation energy to the ablation area, and to obtain physiological parameters in the process of providing the ablation signal to the target electrode; and to determine the ablation category corresponding to the ablation area according to the change trend of the physiological parameters and a preset reference threshold, and when it is determined that the ablation category is a recommended ablation category, continue to provide the ablation signal to the target electrode to ablate the ablation area; wherein the ablation category includes a recommended ablation category and a category not requiring ablation, and the target electrode is one of the multiple electrodes.

[0020] An ablation control device, comprising:

[0021] A signal providing module, configured to provide an ablation signal to a target electrode when an ablation area is determined, so as to apply ablation energy to the ablation area;

[0022] A parameter acquisition module, used for acquiring physiological parameters in the process of providing the ablation signal to the target electrode; wherein the physiological parameters are physiological parameters of the target electrode under the action of the ablation signal;

[0023] A judgment module, configured to determine an ablation category corresponding to the ablation area according to a change trend of the physiological parameter and a preset reference threshold, wherein the ablation category includes a recommended ablation category and a no-ablation category;

[0024] The control module is configured to, when determining that the ablation category is the recommended ablation category, continue to provide an ablation signal to the target electrode to ablate the ablation area.

[0025] In one embodiment, a computer device is provided, including a memory and a processor, wherein the memory stores a computer program, and the processor implements the aforementioned ablation control method when executing the computer program.

[0026] In one embodiment, a computer-readable storage medium is provided, on which a computer program is stored. When the computer program is executed by a processor, the ablation control method described above is implemented.

[0027] In one of the embodiments, a computer program product is provided, wherein the computer program product comprises a computer program, and when the computer program is executed by a processor, the ablation control method described above is implemented.

[0028] The above-mentioned ablation control method, system, device, computer equipment, computer-readable storage medium, and computer program product. The ablation control method first provides an ablation signal to the target electrode when the ablation area is determined, so that the target electrode releases ablation energy to the ablation area, and ablation of the tissue to be ablated in the ablation area can be achieved, thereby achieving a beneficial effect. Then, in the process of providing the ablation signal to the target electrode, the physiological parameters of the target electrode's target object are obtained, so as to facilitate monitoring of the physiological parameters of the target object during the process of applying ablation energy to the target electrode. Since the physiological parameters are obtained in the process of the target electrode providing the ablation signal, the ablation situation can be judged in real time, which is convenient for accurately determining the subsequent operation mode. Then, according to the changing trend of the physiological parameters and the preset reference threshold, the ablation category corresponding to the ablation area can be determined, wherein the ablation category includes a recommended ablation category and a no-ablation category, and then it can be determined whether to continue to provide the ablation signal to the target electrode to ablate the ablation area. When it is determined that the ablation category is the recommended ablation category, the ablation signal continues to be provided to the target electrode to ablate the ablation area. According to the changing trend of the physiological parameters, the situation of the target during the process of applying ablation energy can be accurately determined, and then the physiological parameters are compared with the preset reference threshold to determine the effect of the ablation, thereby facilitating the determination of whether to continue to provide the ablation signal to the target electrode. On the one hand, the effect of the ablation is monitored to ensure that the ablation effect meets the standard, and on the other hand, it avoids damage to the target due to excessive ablation or wrong ablation position, thereby improving the safety of ablation. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] In order to more clearly illustrate the technical solutions in the embodiments of the present application or the conventional technology, the drawings required for use in the embodiments or the conventional technology descriptions are briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0030] Figure 1 is a flow chart of an ablation control method in one embodiment;

[0031] Figure 2 A schematic diagram of changes in heart rate values ​​in one embodiment;

[0032] Figure 3 is a schematic diagram of changes in heart rate values ​​in another embodiment;

[0033] Figure 4 A schematic diagram of changes in heart rate values ​​in yet another embodiment;

[0034] Figure 5 A schematic diagram of changes in heart rate values ​​in yet another embodiment;

[0035] Figure 6 A schematic diagram of changes in heart rate values ​​in yet another embodiment;

[0036] Figure 7 A schematic diagram of changes in blood pressure values ​​in one embodiment;

[0037] Figure 8 is a schematic diagram of changes in blood pressure values ​​in another embodiment;

[0038] Fig. 9 is a schematic diagram of changes in blood pressure values ​​in yet another embodiment;

[0039] Fig.10 is a schematic structural diagram of an ablation system in one embodiment;

[0040] Fig.11 is a schematic structural diagram of an ablation system in another embodiment;

[0041] Fig.12 is a schematic diagram of the structure of a catheter in one embodiment;

[0042] Fig.13 is a flowchart of a work flow of an ablation system in one embodiment;

[0043] Fig.14 is a schematic structural diagram of an ablation control device in one embodiment;

[0044] Fig.15 FIG. 4 is a diagram showing the internal structure of a computer device in one embodiment.

[0045] Description of reference numerals:

[0046] 10-catheter, 20-electrode, 30-ablation module, 40-control module, 50-collection module, 11-support part, 12-electrode part. DETAILED DESCRIPTION

[0047] In order to facilitate understanding of the present application, the present application will be described more fully below with reference to the relevant drawings. Embodiments of the present application are provided in the drawings. However, the present application can be implemented in many different forms and is not limited to the embodiments described herein. On the contrary, the purpose of providing these embodiments is to make the disclosure of the present application more thorough and comprehensive.

[0048] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those commonly understood by those skilled in the art to which this application belongs. The terms used herein in the specification of this application are only for the purpose of describing specific embodiments and are not intended to limit this application.

[0049] It can be understood that the terms "first", "second", etc. used in the present application can be used in this article to describe various elements, but these elements are not limited by these terms. These terms are only used to distinguish the first element from another element.

[0050] Spatially relative terms such as "under," "beneath," "below," "under," "above," "above," and the like may be used herein to describe the relationship of an element or feature shown in the figures to other elements or features. It should be understood that, in addition to the orientations shown in the figures, spatially relative terms also include different orientations of the device in use and operation. For example, if the device in the accompanying drawings is flipped, an element or feature described as "under other elements" or "under it" or "under it" will be oriented as being "above" the other elements or features. Thus, the exemplary terms "under" and "under" may include both upper and lower orientations. In addition, the device may also include additional orientations (e.g., rotated 90 degrees or other orientations), and the spatial descriptors used herein are interpreted accordingly.

[0051] It should be noted that when an element is considered to be "connected" to another element, it can be directly connected to the other element, or connected to the other element through an intermediate element. In addition, the "connection" in the following embodiments should be understood as "electrical connection", "communication connection", etc. if there is transmission of electrical signals or data between the connected objects.

[0052] When used herein, the singular forms "a", "an", and "said / the" may also include plural forms, unless the context clearly indicates otherwise. It should also be understood that the terms "include / comprise" or "have" and the like specify the presence of stated features, wholes, steps, operations, components, parts, or combinations thereof, but do not exclude the possibility of the presence or addition of one or more other features, wholes, steps, operations, components, parts, or combinations thereof. At the same time, the term "and / or" used in this specification includes any and all combinations of the relevant listed items.

[0053] In one embodiment, Figure 1 As shown, a method for ablation control is provided, the method comprising:

[0054] Step S100 , when the ablation area is determined, an ablation signal is provided to the target electrode to apply ablation energy to the ablation area.

[0055] Among them, the ablation area is predetermined, and the location of the ablation area can be determined according to the physiological parameters of the target when the electrode releases the electrical stimulation signal. The location of the ablation area can also be determined by endoscopy, or by magnetic resonance imaging or computed tomography.

[0056] The target electrode is an electrode whose action range covers at least a part of the ablation area. When the target electrode releases ablation energy, at least a part of the ablation area can be ablated. The ablation signal can be high-power ablation energy, and its unit is watt. High-power ablation energy refers to energy that can cause destructive damage to cells in a specific part and cause them to die when acting on a specific part. Exemplarily, the output power of the ablation energy can be 0-40W, which is adjusted as needed.

[0057] Step S110, obtaining physiological parameters during the process of providing an ablation signal to the target electrode.

[0058] The physiological parameter is a physiological parameter of an object acted upon by the target electrode under the action of the ablation signal.

[0059] Among them, when the target electrode releases ablation energy to the ablation area, the physiological parameters of the target will change. The physiological parameters of the target can be collected by the detection equipment at a set frequency to obtain discrete physiological parameters, so as to determine the effect of ablation later.

[0060] Step S120: determining the ablation category corresponding to the ablation area according to the change trend of the physiological parameter and the preset reference threshold.

[0061] Among them, in the process of applying ablation energy to the ablation area, there will be certain differences in the physiological parameters of the target when the ablation energy is applied to the pulmonary artery sympathetic nerves in the ablation area and when the ablation energy is not applied to the pulmonary artery sympathetic nerves in the ablation area. Therefore, according to the changing trend of the physiological parameters, combined with the preset benchmark threshold as a reference standard, it can be determined whether the pulmonary artery sympathetic nerves in the ablation area have been ablated. If the pulmonary artery sympathetic nerves have been ablated, the ablation signal can be stopped from being provided to the target electrode. If the pulmonary artery sympathetic nerves have not been ablated, the ablation signal can continue to be provided to the target electrode.

[0062] Among them, the ablation categories include recommended ablation categories and no ablation required categories. In the process of applying ablation energy to the ablation area, whether the ablation energy acts on the pulmonary artery sympathetic nerves will directly affect the changing trend of the physiological parameters of the object. Therefore, according to the changing trend of the physiological parameters, combined with the preset benchmark threshold as a reference standard, it can be determined whether the ablation energy acts on the pulmonary artery sympathetic nerves, that is, whether the ablation is effective and how the ablation is. This is because the ablation area is a relatively large range, and the pulmonary artery sympathetic nerves only exist in a certain position within the ablation area, and the coverage range of the target electrode is also smaller than the range of the ablation area. Therefore, during ablation, it is possible that the target electrode applies ablation energy to the ablation area, but the ablation energy does not act on the pulmonary artery sympathetic nerves. Therefore, it is necessary to determine the ablation category corresponding to the ablation area based on the changing trend of the physiological parameters and the preset benchmark threshold.

[0063] Step S130: When it is determined that the ablation category is the recommended ablation category, the ablation signal is continued to be provided to the target electrode to ablate the ablation area.

[0064] When the ablation category is determined to be the recommended ablation category, it means that the ablation energy released by the current target electrode is acting on the pulmonary artery sympathetic nerves, so the ablation signal continues to be provided to the target electrode, and ablation continues until the ablation category is determined to be a category that does not require ablation.

[0065] In this embodiment, the ablation control method first provides an ablation signal to the target electrode when the ablation area is determined, so that the target electrode releases ablation energy to the ablation area, and ablation of the tissue to be ablated in the ablation area can be achieved, thereby achieving a beneficial effect. Then, in the process of providing the ablation signal to the target electrode, the physiological parameters of the target electrode's target object are obtained, so as to facilitate monitoring of the physiological parameters of the target object in the process of applying ablation energy to the target electrode. Since the physiological parameters are obtained in the process of the target electrode providing the ablation signal, the ablation situation can be judged in real time, which is convenient for accurately determining the subsequent operation mode. Then, according to the changing trend of the physiological parameters and the preset reference threshold, the ablation category corresponding to the ablation area can be determined, wherein the ablation category includes a recommended ablation category and a no-ablation category, and then it can be determined whether to continue to provide the ablation signal to the target electrode to ablate the ablation area. When it is determined that the ablation category is the recommended ablation category, the ablation signal continues to be provided to the target electrode to ablate the ablation area. According to the changing trend of the physiological parameters, the situation of the target during the process of applying ablation energy can be accurately determined, and then the physiological parameters are compared with the preset reference threshold to determine the effect of the ablation, thereby facilitating the determination of whether to continue to provide the ablation signal to the target electrode. On the one hand, the effect of the ablation is monitored to ensure that the ablation effect meets the standard, and on the other hand, it avoids damage to the target due to excessive ablation or wrong ablation position, thereby improving the safety of ablation.

[0066] In one embodiment, the physiological parameter includes a heart rate value, and step S120 determines the ablation category corresponding to the ablation area according to the change trend of the physiological parameter and a preset reference threshold value. Specifically, it includes: when the change trend of the heart rate value meets the first preset heart rate condition, determining that the ablation category corresponding to the ablation area is a recommended ablation category.

[0067] Among them, the first preset heart rate condition includes: the heart rate value shows a continuous increasing trend, and the heart rate values ​​within the set time are all greater than the heart rate reference threshold, or the heart rate value shows a continuous decreasing trend, and the heart rate values ​​within the set time are all less than the heart rate reference threshold.

[0068] Specifically, when the heart rate value shows a continuous upward trend, and the heart rate values ​​within the set time are all greater than the heart rate reference threshold, the ablation area can be classified as the first category. When the heart rate value shows a continuous downward trend, and the heart rate values ​​within the set time are all less than the heart rate reference threshold, the ablation area can be classified as the second category. Both the first category and the second category represent that there are still pulmonary artery sympathetic nerves in the ablation area, so it is necessary to continue ablation of the ablation area. This is because of the existence of sympathetic nerves. After receiving stimulation signals, the sympathetic nerves will cause a large change in the heart rate value of the subject. If there are no sympathetic nerves, such changes will not occur.

[0069] For example, the first category of the change trend graph of the heart rate value is as follows: Figure 2 As shown, the second category of the heart rate value change trend diagram is as follows Figure 3 shown.

[0070] In this embodiment, whether the current ablation area is the recommended ablation area is determined by the change trend of the heart rate value, so that it can be accurately determined whether it is necessary to continue to provide the ablation signal to the target electrode, thereby ensuring the effectiveness and safety of ablation.

[0071] In one embodiment, the category of not requiring ablation includes a first subcategory and a second subcategory. Step S120, determining the ablation category corresponding to the ablation area according to the change trend of the physiological parameter and the preset reference threshold. Including:

[0072] When the change trend of the heart rate value meets the second preset heart rate condition, it is determined that the ablation category corresponding to the ablation area is the first subcategory.

[0073] Among them, the second preset heart rate condition includes: the absolute value of the rate of change of the heart rate value relative to the heart rate reference threshold is less than the set threshold, and the ablation area in this case is classified as the third category, that is, in the case of this embodiment, the first subcategory and the third category have the same meaning, both referring to the category of the ablation area when the second preset heart rate condition is met. The first subcategory represents that a part of the ablation area corresponding to the current target electrode does not need to be ablated, because the physiological parameters of the subject do not change significantly under the action of the ablation signal, so it represents that there is no pulmonary artery sympathetic nerve in a part of the ablation area corresponding to the current target electrode, and no ablation is required.

[0074] When the change trend of the heart rate value meets the third preset heart rate condition, it is determined that the ablation category corresponding to the ablation area is the second subcategory.

[0075] Among them, the third preset heart rate condition includes: the heart rate value first shows an upward trend and rises to above the heart rate reference threshold, and then shows a downward trend and drops to below or equal to the heart rate reference threshold, or the heart rate value first shows a downward trend and drops to below the heart rate reference threshold, and then shows an upward trend and rises to above or equal to the heart rate reference threshold.

[0076] Specifically, when the heart rate value first shows an upward trend and rises to a value higher than the heart rate reference threshold, and then shows a downward trend and falls to a value lower than or equal to the heart rate reference threshold, the ablation area can be classified into the fourth category. When the heart rate value first shows a downward trend and falls to a value lower than the heart rate reference threshold, and then shows an upward trend and rises to a value higher than or equal to the heart rate reference threshold, the ablation area can be classified into the fifth category. The fourth and fifth categories both represent that there are pulmonary artery sympathetic nerves in the ablation area but they have been cleared by ablation, so there is no need to continue ablation of the ablation area. This is because the existence of sympathetic nerves will cause a large change in the heart rate value of the object after being stimulated by the signal, but after the sympathetic nerves are cleared by ablation, the heart rate value will recover after the change, indicating that the ablation is successful, that is, the second subcategory represents the category of the ablation area where the pulmonary artery sympathetic nerves exist but have been cleared by ablation. There are two different forms of changes in the heart rate value of the ablation area where the pulmonary artery sympathetic nerves exist but have been cleared by ablation, and the fourth and fifth categories represent the categories of the ablation area in these two forms of expression, respectively.

[0077] For example, a table for classifying the change trend of the heart rate value is shown in Table 1:

[0078] Table 1. Classification table of heart rate value change trend

[0079]

[0080] For example, the third category of the heart rate value change trend diagram is as follows: Figure 4 As shown, the change trend of the fourth category of heart rate value is as follows Figure 5 As shown, the fifth category of heart rate value change trend diagram is as follows Figure 6 shown.

[0081] In this embodiment, whether the current ablation area belongs to the category of not requiring ablation is determined by the changing trend of the heart rate value, and whether it belongs to the first subcategory or the second subcategory is further determined, so that it can be accurately determined whether it is necessary to continue to provide ablation signals to the target electrode, thereby ensuring the effectiveness and safety of ablation. The specific distinction between the first subcategory and the second subcategory also facilitates the statistics of the success rate and effect of ablation.

[0082] In one embodiment, the physiological parameter includes a blood pressure value. Step S120 determines the ablation category corresponding to the ablation area according to the change trend of the physiological parameter and a preset reference threshold.

[0083] When the change trend of the blood pressure value meets the first preset blood pressure condition, the ablation category corresponding to the ablation area is determined to be the recommended ablation category.

[0084] Among them, the first preset blood pressure condition includes: the blood pressure value shows a continuous upward trend, and the blood pressure values ​​within the set time are all greater than the blood pressure reference threshold, or the blood pressure value first shows a downward trend and then an upward trend, and the blood pressure values ​​within the set time are all greater than the blood pressure reference threshold.

[0085] Specifically, when the blood pressure value shows a continuous upward trend, and the blood pressure values ​​within the set time are all greater than the blood pressure reference threshold, the current ablation area can be classified as the sixth category. When the blood pressure value first shows a downward trend and then an upward trend, and the blood pressure values ​​within the set time are all greater than the blood pressure reference threshold, the current ablation area can be classified as the seventh category. Both the sixth and seventh categories represent that there are still pulmonary artery sympathetic nerves in the ablation area, so it is necessary to continue ablation of the ablation area. This is because of the existence of sympathetic nerves. After receiving stimulation signals, the sympathetic nerves will cause a large change in the subject's blood pressure value. If there are no sympathetic nerves, such changes will not occur.

[0086] For example, the variation trend diagram of the sixth category of blood pressure values ​​is as follows: Figure 7 As shown, the seventh category of blood pressure value change trend chart is as follows Figure 8 shown.

[0087] In this embodiment, whether the current ablation area is the recommended ablation area is determined by the change trend of the blood pressure value, so that it can be accurately determined whether it is necessary to continue to provide the ablation signal to the target electrode, thereby ensuring the effectiveness and safety of ablation.

[0088] In one embodiment, the category of not requiring ablation includes a first subcategory and a second subcategory. Step S120, determining the ablation category corresponding to the ablation area according to the change trend of the physiological parameter and the preset reference threshold. Including:

[0089] When the change trend of the blood pressure value meets the second preset blood pressure condition, it is determined that the ablation category corresponding to the ablation area is the second subcategory.

[0090] Among them, the second preset blood pressure condition includes: the blood pressure value first shows an upward trend and rises to a level higher than the blood pressure reference threshold, and then shows a downward trend and drops to a level lower than or equal to the blood pressure reference threshold.

[0091] Specifically, when the blood pressure value first shows an upward trend and rises to a level higher than the blood pressure reference threshold, and then shows a downward trend and falls to a level lower than or equal to the blood pressure reference threshold, the ablation area can be classified into the eighth category. The eighth category means that there are pulmonary artery sympathetic nerves in the ablation area but they have been cleared by ablation, so there is no need to continue ablation of the ablation area. This is because the existence of sympathetic nerves will cause a large change in the heart rate value of the subject after being stimulated by a signal. However, after the sympathetic nerves are cleared by ablation, the heart rate value will recover after the change, indicating that the ablation is successful.

[0092] For example, the change trend diagram of the eighth category of blood pressure value is as follows: Fig. 9 shown.

[0093] Step S120, determining the ablation category corresponding to the ablation area according to the change trend of the physiological parameter and the preset reference threshold value. It also includes: when it is determined that the ablation category corresponding to the ablation area is not the recommended ablation category and is not the second subcategory, determining that the ablation category corresponding to the ablation area is the first subcategory.

[0094] Among them, the first subcategory at this time represents that there are no pulmonary artery sympathetic nerves in a part of the ablation area corresponding to the current target electrode, and no ablation is required. This situation is classified as the ninth category, that is, the category of the ablation area where there is no pulmonary artery sympathetic nerves determined according to the blood pressure value is classified as the ninth category.

[0095] For example, a table for classifying the change trend of blood pressure values ​​is shown in Table 2:

[0096] Table 2. Classification table of blood pressure value change trend

[0097]

[0098] In this embodiment, whether the current ablation area belongs to the category of not requiring ablation is determined by the changing trend of the blood pressure value, and whether it belongs to the first subcategory or the second subcategory is further determined, so that it can be accurately determined whether it is necessary to continue to provide ablation signals to the target electrode, thereby ensuring the effectiveness and safety of ablation. The specific distinction between the first subcategory and the second subcategory also facilitates the statistics of the success rate and effect of ablation.

[0099] In one embodiment, the ablation control method further includes: when it is determined that the ablation category is a recommended ablation category, continuing to provide the ablation signal to the target electrode according to a preset strategy.

[0100] The preset strategy is: prolonging the time for providing the ablation signal to the target electrode, and / or increasing the power of the ablation signal provided to the target electrode.

[0101] In this embodiment, when the ablation category is determined to be the recommended ablation category, it means that the ablation area needs to continue to be ablated, and it also means that the energy of the ablation signal currently provided is not enough, so the ablation signal continues to be provided, that is, the ablation time is extended, or the power of the ablation signal is increased so that the ablation of the sympathetic nerves in the ablation area can be quickly and effectively achieved.

[0102] In one embodiment, the ablation control method further includes: when the ablation category is determined to be the first subcategory, reconfirming a new ablation area within a preset range around the target electrode.

[0103] Specifically, when the ablation category is determined to be the first subcategory, it means that there are no pulmonary artery sympathetic nerves in a part of the ablation area corresponding to the current target electrode, but there are pulmonary artery sympathetic nerves in the ablation area, so it is necessary to find a new ablation area near the target electrode. The way to find it is to release an electrical stimulation signal in an area within a preset range around the target electrode, and then determine the position of the new ablation area according to the physiological parameters of the object.

[0104] The ablation control method further includes: after reconfirming the new ablation area, taking the electrode corresponding to the new ablation area as a new target electrode, providing an ablation signal to the new target electrode, so as to apply ablation energy to the new ablation area.

[0105] Specifically, after reconfirming the new ablation area, an electrode whose effective range can cover at least a part of the new ablation area is selected as a new target electrode according to the location of the new ablation area. By providing an ablation signal to the new target electrode, the pulmonary artery sympathetic nerves that may exist in the new ablation area can be ablated. During the ablation process, the above steps are repeated to determine the ablation category of the new ablation area until the ablation category is determined to be the second subcategory.

[0106] In this embodiment, when it is determined that pulmonary artery sympathetic nerves do not exist in a part of the ablation area corresponding to the current target electrode, a new ablation area is reconfirmed within a preset range around the target electrode, and then an ablation signal is provided to the target electrode corresponding to the new ablation area to facilitate ablation of the pulmonary artery sympathetic nerves in the new ablation area. When it is detected that no sympathetic nerves exist in the area corresponding to the current target electrode, the position of the sympathetic nerves is re-searched and ablation is performed again, thereby ensuring that the detected pulmonary artery sympathetic nerves can be ablated.

[0107] It should be understood that although Figure 1 The steps in the flowchart are shown in sequence as indicated by the arrows, but these steps are not necessarily executed in the order indicated by the arrows. Unless otherwise specified in this document, there is no strict order restriction for the execution of these steps, and these steps can be executed in other orders. Moreover, Figure 1 At least part of the steps may include multiple steps or multiple stages. These steps or stages are not necessarily performed at the same time, but can be performed at different times. The execution order of these steps or stages is not necessarily sequential, but can be performed in turn or alternately with other steps or at least part of the steps or stages in other steps.

[0108] In one embodiment, Fig.10As shown, an ablation system is provided, comprising: an electrode assembly, an ablation module 30, a control module 40, and a collection module 50, wherein:

[0109] The electrode assembly includes a catheter 10 and a plurality of electrodes 20 spaced apart on the catheter 10 .

[0110] Among them, Fig.11 As shown, the catheter 10 includes a support portion 11 and an electrode portion 12, and the electrode portion 12 is a flexible hose. A plurality of electrodes 20 are arranged at intervals on the electrode portion 12. The support portion 11 may be a sheath of the electrode portion 12, which is used to support the catheter 10 to prevent the catheter 10 from being deformed and to enable the catheter 10 to smoothly enter the body of the target object, while the electrode portion 12 is a flexible hose that can be bent at will. On the one hand, it avoids stabbing the tissue of the target object, and on the other hand, it is also convenient to bend to better cover the area of ​​the target object's tissue that needs to be ablated. The electrode 20 is a device that can output energy and can release energy to the vicinity of its setting position to achieve the effect of stimulation or ablation. The electrodes 20 are arranged at intervals on the catheter 10, so when the catheter 10 is inserted into the body of the target object, the energy released by each electrode 20 can cover different areas. Preferably, the areas covered by the energy released by each electrode 20 do not overlap. For example, the electrode portion 12 can be as follows Fig.12 As shown, the electrode 20 is bent into a ring shape, so that the area covered by the electrode 20 is larger. Preferably, the electrode portion 12 is placed at the left and right pulmonary artery orifices or the pulmonary artery trunk, and then the pulmonary artery sympathetic nerve is found. The ablation module is connected to a plurality of electrodes respectively, and is used to provide an ablation signal to each electrode, and the ablation signal is used to ablate the pulmonary artery sympathetic nerve.

[0111] The acquisition module 50 is used to acquire physiological parameters of the subject to which the multiple electrodes act.

[0112] The control module 40 is connected to the ablation module 30 and the acquisition module 50 respectively, and is used to control the ablation module 30 to provide an ablation signal to the target electrode when the ablation area is determined, so as to apply ablation energy to the ablation area, and obtain physiological parameters in the process of providing the ablation signal to the target electrode; and determine the ablation category corresponding to the ablation area according to the change trend of the physiological parameters and the preset reference threshold value, and when the ablation category is determined to be the recommended ablation category, continue to provide the ablation signal to the target electrode to ablate the ablation area.

[0113] The ablation categories include a recommended ablation category and a no-ablation-needed category.

[0114] The physiological parameter is a physiological parameter of an object of the target electrode under the action of the ablation signal, and the target electrode is one of the multiple electrodes.

[0115] The ablation module 30 can output an ablation signal, which can be a high-power ablation energy in watts. The high-power ablation energy refers to energy that can cause destructive damage to cells in a specific part and cause them to die when acting on the specific part. For example, the output power of the ablation energy can be 0-40W, which can be adjusted as needed.

[0116] Specifically, the target electrode is an electrode whose action range covers at least a part of the ablation area. When the target electrode releases ablation energy, at least a part of the ablation area can be ablated. When the target electrode releases ablation energy to the ablation area, the physiological parameters of the target object will change. The physiological parameters of the target object can be collected by the detection device according to the set frequency to obtain discrete physiological parameters, so as to facilitate the subsequent determination of the effect of ablation. In the process of applying ablation energy to the ablation area, when the ablation energy is applied to the pulmonary artery sympathetic nerves in the ablation area and when the ablation energy is not applied to the pulmonary artery sympathetic nerves in the ablation area, there will be certain differences in the physiological parameters of the target object. Therefore, according to the change trend of the physiological parameters, combined with the preset reference threshold as a reference standard, it can be determined whether the pulmonary artery sympathetic nerves in the ablation area have been ablated. Then, if the pulmonary artery sympathetic nerves have been ablated, the ablation signal can be stopped from being provided to the target electrode. If the pulmonary artery sympathetic nerves have not been ablated, the ablation signal can continue to be provided to the target electrode.

[0117] Specifically, Fig.13 As shown, the workflow of the ablation system of the present application includes:

[0118] Step S1300, obtaining a preset reference threshold.

[0119] Step S1310, providing an electrical stimulation signal to the target electrode pair.

[0120] The initial target electrode pair is a randomly selected electrode pair. The target electrode pair includes at least one electrode.

[0121] The time for applying the electrical stimulation signal may be 0-180 seconds, preferably 60 seconds.

[0122] Step S1320, obtaining physiological parameters in the process of providing electrical stimulation signals to the electrode pairs.

[0123] Step S1330, determining whether the physiological parameter meets the preset condition. If the physiological parameter meets the preset condition, executing step S1340, otherwise, selecting another electrode pair that has not been provided with an electrical stimulation signal as the target electrode pair, and returning to executing step S1310.

[0124] Step S1340, providing an ablation signal to the target electrode.

[0125] The time for applying the ablation signal may be 0-180 seconds, preferably 60 seconds.

[0126] Step S1350, obtaining physiological parameters in the process of providing ablation signals to the target electrode.

[0127] Step S1360, determining whether the ablation category corresponding to the ablation region is a recommended ablation category. If the ablation category of the ablation region is determined to be a recommended ablation category, step S1370 is executed; if the ablation category of the ablation region is determined to be a category that does not require ablation, step S1380 is executed.

[0128] Step S1370: Continue to provide the ablation signal to the target electrode according to the preset strategy, wherein the preset strategy is: prolonging the time of providing the ablation signal to the target electrode, and / or increasing the power of the ablation signal provided to the target electrode.

[0129] Step S1380, determine whether all electrode pairs have been provided with electrical stimulation signals. If all electrode pairs have been provided with electrical stimulation signals, it is determined that ablation is completed, otherwise another electrode pair that has not been provided with electrical stimulation signals is selected as the target electrode pair, and the process returns to step S1310.

[0130] In this embodiment, when the ablation area is determined, the control module controls the ablation module to provide an ablation signal to the target electrode, so that the target electrode releases ablation energy to the ablation area, and ablation of the tissue to be ablated in the ablation area can be achieved, thereby achieving a beneficial effect. Then, in the process of providing the ablation signal to the target electrode, the physiological parameters of the target electrode's target object are obtained through the acquisition module, so that the physiological parameters of the target object can be monitored in the process of applying the ablation energy to the target electrode. Since the physiological parameters are obtained in the process of the target electrode providing the ablation signal, the ablation situation can be judged in real time, which is convenient for accurately determining the subsequent operation mode. Then, based on the changing trend of the physiological parameters and the preset reference threshold, it is determined whether to continue to provide the ablation signal to the target electrode to ablate the ablation area. According to the changing trend of the physiological parameters, the situation of the target during the process of applying ablation energy can be accurately determined, and then the physiological parameters can be compared with the preset reference threshold to determine the effect of ablation, so as to facilitate the determination of whether to continue to provide the ablation signal to the target electrode. On the one hand, the effect of ablation is monitored to ensure that the ablation effect meets the standard. On the other hand, it avoids damage to the target due to excessive ablation or wrong ablation position, thereby improving the safety of ablation.

[0131] In one embodiment, Fig.14As shown, an ablation control device is provided, including: a signal providing module 1401, a parameter acquiring module 1402, a judging module 1403, and a control module 1404, wherein:

[0132] The signal providing module 1401 is used to provide an ablation signal to the target electrode when the ablation area is determined, so as to apply ablation energy to the ablation area.

[0133] The parameter acquisition module 1402 is used to acquire physiological parameters in the process of providing the ablation signal to the target electrode, wherein the physiological parameter information is the physiological parameters of the target electrode under the action of the ablation signal.

[0134] The judgment module 1403 is used to determine the ablation category corresponding to the ablation area according to the change trend of the physiological parameters and the preset reference threshold, wherein the ablation category includes a recommended ablation category and a no-ablation category.

[0135] The control module 1404 is configured to continue to provide an ablation signal to the target electrode to ablate the ablation area when the ablation category is determined to be the recommended ablation category.

[0136] In one embodiment, the category determination unit further includes: a first category determination subunit, a second category determination subunit, a third category determination subunit, a fourth category determination subunit, a fifth category determination subunit, and a sixth category determination subunit, wherein:

[0137] The first category determination subunit is used to determine that the ablation category corresponding to the ablation area is a recommended ablation category when the change trend of the heart rate value meets the first preset heart rate condition. The first preset heart rate condition includes: the heart rate value shows a continuous upward trend, and the heart rate values ​​within the set time are all greater than the heart rate reference threshold, or the heart rate value shows a continuous downward trend, and the heart rate values ​​within the set time are all less than the heart rate reference threshold.

[0138] The second category determination subunit is used to determine that the ablation category corresponding to the ablation area is the first subcategory when the change trend of the heart rate value meets the second preset heart rate condition. The second preset heart rate condition includes: the absolute value of the change rate of the heart rate value relative to the heart rate reference threshold is less than the set threshold.

[0139] The third category determination subunit is used to determine that the ablation category corresponding to the ablation area is the second subcategory when the changing trend of the heart rate value meets the third preset heart rate condition; wherein the third preset heart rate condition includes: the heart rate value first shows an upward trend and rises to above the heart rate baseline threshold, and then shows a downward trend and drops to below or equal to the heart rate baseline threshold, or the heart rate value first shows a downward trend and drops to below the heart rate baseline threshold, and then shows an upward trend and rises to above or equal to the heart rate baseline threshold.

[0140] The fourth category determination subunit is used to determine that the ablation category corresponding to the ablation area is the recommended ablation category when the changing trend of the blood pressure value meets the first preset blood pressure condition; wherein the first preset blood pressure condition includes: the blood pressure value shows a continuous increasing trend, and the blood pressure values ​​within the set time are all greater than the blood pressure reference threshold; or, the blood pressure value first shows a downward trend and then an upward trend, and the blood pressure values ​​within the set time are all greater than the blood pressure reference threshold.

[0141] The fifth category determination subunit is used to determine that the ablation category corresponding to the ablation area is the second subcategory when the changing trend of the blood pressure value meets the second preset blood pressure condition; wherein the second preset blood pressure condition includes: the blood pressure value first shows an upward trend and rises to above the blood pressure reference threshold, and then shows a downward trend and drops to below or equal to the blood pressure reference threshold.

[0142] The sixth category determination subunit is used to determine that the ablation category corresponding to the ablation area is the first subcategory when it is determined that the ablation category corresponding to the ablation area is not the recommended ablation category and is not the second subcategory.

[0143] In one embodiment, the ablation control device further includes: an ablation adjustment module. The ablation adjustment module is used to continue to provide an ablation signal to the target electrode according to a preset strategy when the ablation category is determined to be a recommended ablation category, wherein the preset strategy is: extending the time for providing the ablation signal to the target electrode, and / or increasing the power of the ablation signal provided to the target electrode.

[0144] In one embodiment, the ablation control device further includes: a region determination module. The region determination module is used to reconfirm a new ablation region within a preset range around the ablation region when the ablation category is determined to be the first subcategory.

[0145] In one embodiment, the ablation control device further includes: a signal providing module. The signal providing module is used to, after re-confirming the new ablation area, use the electrode corresponding to the new ablation area as a new target electrode and provide an ablation signal to the new target electrode to apply ablation energy to the new ablation area.

[0146] For the specific definition of the ablation control device, please refer to the definition of the ablation control method above, which will not be repeated here. The various modules in the above-mentioned ablation control device can be implemented in whole or in part by software, hardware and a combination thereof. The above-mentioned modules can be embedded in or independent of the processor in the computer device in the form of hardware, or can be stored in the memory of the computer device in the form of software, so that the processor can call and execute the operations corresponding to the above modules. It should be noted that the division of modules in the embodiment of the present application is schematic and is only a logical function division. There may be other division methods in actual implementation.

[0147] In one embodiment, a computer device is provided, wherein the internal structure diagram of the computer device can be as follows: Fig.15 As shown. The computer device includes a processor, a memory and a network interface connected through a system bus. Among them, the processor of the computer device is used to provide computing and control capabilities. The memory of the computer device includes a non-volatile storage medium and an internal memory. The non-volatile storage medium stores an operating system, a computer program and a database. The internal memory provides an environment for the operation of the operating system and the computer program in the non-volatile storage medium. The network interface of the computer device is used to communicate with an external terminal through a network connection. When the computer program is executed by the processor, an ablation control method is implemented.

[0148] Those skilled in the art will understand that Fig.15 The structure shown in the figure is only a block diagram of a part of the structure related to the solution of the present application, and does not constitute a limitation on the computer device to which the solution of the present application is applied. The specific computer device may include more or fewer components than those shown in the figure, or combine certain components, or have a different arrangement of components.

[0149] In one embodiment, a computer device is provided, including a memory and a processor, wherein a computer program is stored in the memory, and the processor implements the steps in the above-mentioned method embodiments when executing the computer program.

[0150] In one embodiment, a computer-readable storage medium is provided, on which a computer program is stored. When the computer program is executed by a processor, the steps in the above-mentioned method embodiments are implemented.

[0151] In one embodiment, a computer program product is provided, including a computer program, which implements the steps in the above method embodiments when executed by a processor.

[0152] Those of ordinary skill in the art can understand that all or part of the processes in the above-mentioned embodiment methods can be completed by instructing the relevant hardware through a computer program, and the computer program can be stored in a non-volatile computer-readable storage medium. When the computer program is executed, it can include the processes of the embodiments of the above-mentioned methods. Among them, any reference to memory, storage, database or other media used in the embodiments provided in this application can include at least one of non-volatile and volatile memory. Non-volatile memory can include read-only memory (ROM), magnetic tape, floppy disk, flash memory or optical memory, etc. Volatile memory can include random access memory (RAM) or external cache memory. As an illustration and not limitation, RAM can be in various forms, such as static random access memory (SRAM) or dynamic random access memory (DRAM).

[0153] In the description of this specification, the description with reference to the terms "some embodiments", "other embodiments", "ideal embodiments", etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic descriptions of the above terms do not necessarily refer to the same embodiment or example.

[0154] The technical features of the above embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0155] The above-mentioned embodiments only express several implementation methods of the present application, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the invention patent. It should be pointed out that, for a person of ordinary skill in the art, several variations and improvements can be made without departing from the concept of the present application, and these all belong to the protection scope of the present application. Therefore, the protection scope of the patent of the present application shall be subject to the attached claims.

Claims

1. An ablation control method, characterized in that: include: When the ablation area is determined, providing an ablation signal to the target electrode to apply ablation energy to the ablation area; In the process of providing the ablation signal to the target electrode, a physiological parameter is acquired; wherein the physiological parameter is a physiological parameter of an object acted upon by the target electrode under the action of the ablation signal; Determining the ablation category corresponding to the ablation area according to the change trend of the physiological parameter and the preset reference threshold, wherein the ablation category includes a recommended ablation category and a no-ablation category; When it is determined that the ablation category is the recommended ablation category, the ablation signal continues to be provided to the target electrode to ablate the ablation area.

2. The ablation control method according to claim 1, characterized in that: The physiological parameter includes a heart rate value, the preset reference threshold includes a heart rate reference threshold, and determining the ablation category corresponding to the ablation area according to the change trend of the physiological parameter and the preset reference threshold includes: When the change trend of the heart rate value satisfies the first preset heart rate condition, the ablation category corresponding to the ablation area is determined to be the recommended ablation category; wherein, The first preset heart rate condition includes: the heart rate value shows a continuous increasing trend, and the heart rate values ​​within the set time are all greater than the heart rate reference threshold, or the heart rate value shows a continuous decreasing trend, and the heart rate values ​​within the set time are all less than the heart rate reference threshold.

3. The ablation control method according to claim 2, characterized in that: The category not requiring ablation includes a first subcategory and a second subcategory; and the ablation category corresponding to the ablation area is determined according to the change trend of the heart rate value and the heart rate reference threshold value, including: In the case where the change trend of the heart rate value satisfies the second preset heart rate condition, determining that the ablation category corresponding to the ablation area is the first subcategory; wherein the second preset heart rate condition includes: the absolute value of the change rate of the heart rate value relative to the heart rate reference threshold is less than a set threshold; When the changing trend of the heart rate value satisfies the third preset heart rate condition, the ablation category corresponding to the ablation area is determined to be the second subcategory; wherein the third preset heart rate condition includes: the heart rate value first shows an upward trend, and rises to above the heart rate baseline threshold, and then shows a downward trend, and drops to below or equal to the heart rate baseline threshold, or the heart rate value first shows a downward trend, and drops to below the heart rate baseline threshold, and then shows an upward trend, and rises to above or equal to the heart rate baseline threshold.

4. The ablation control method according to claim 1, characterized in that: The physiological parameter includes a blood pressure value, the preset reference threshold includes a blood pressure reference threshold, and determining the ablation category corresponding to the ablation area according to the change trend of the physiological parameter and the preset reference threshold includes: When the change trend of the blood pressure value satisfies the first preset blood pressure condition, the ablation category corresponding to the ablation area is determined to be the recommended ablation category; wherein, The first preset blood pressure condition includes: the blood pressure value shows a continuous upward trend, and the blood pressure values ​​within a set time period are all greater than the blood pressure reference threshold; or, the blood pressure value first shows a downward trend and then an upward trend, and the blood pressure values ​​within a set time period are all greater than the blood pressure reference threshold.

5. The ablation control method according to claim 4, characterized in that: The category that does not require ablation includes a first subcategory and a second subcategory; and the determining, according to the change trend of the blood pressure value and the blood pressure reference threshold, the ablation category corresponding to the ablation area includes: When the change trend of the blood pressure value satisfies a second preset blood pressure condition, determining that the ablation category corresponding to the ablation area is a second subcategory; wherein the second preset blood pressure condition includes: The blood pressure value first shows an upward trend and rises to a level higher than the blood pressure reference threshold, and then shows a downward trend and drops to a level lower than or equal to the blood pressure reference threshold.

6. The ablation control method according to claim 5, characterized in that: The determining, according to the change trend of the blood pressure value and the blood pressure reference threshold, the ablation category corresponding to the ablation area further includes: When it is determined that the ablation category corresponding to the ablation area is not the recommended ablation category and is not the second subcategory, the ablation category corresponding to the ablation area is determined to be the first subcategory.

7. The ablation control method according to claim 2 or 4, characterized in that: The ablation control method further includes: When it is determined that the ablation category is the recommended ablation category, continue to provide the ablation signal to the target electrode according to a preset strategy, wherein the preset strategy is: extending the time of providing the ablation signal to the target electrode, and / or increasing the power of the ablation signal provided to the target electrode.

8. The ablation control method according to claim 3 or 5, characterized in that: The ablation control method further includes: When it is determined that the ablation category is the first subcategory, a new ablation area is reconfirmed within a preset range around the target electrode.

9. The ablation control method according to claim 8, characterized in that: The ablation control method further includes: After the new ablation area is reconfirmed, the electrode corresponding to the new ablation area is used as a new target electrode, and an ablation signal is provided to the new target electrode to apply ablation energy to the new ablation area.

10. An ablation system, characterized in that: include: An electrode assembly, comprising a catheter and a plurality of electrodes spaced apart on the catheter; an ablation module, connected to the plurality of electrodes respectively, and used for providing an ablation signal to each of the electrodes, wherein the ablation signal is used for ablating the sympathetic nerves of the pulmonary artery; A collection module, used for collecting physiological parameters of the subject of the plurality of electrodes; a control module, connected to the ablation module and the acquisition module respectively, for controlling the ablation module to provide an ablation signal to a target electrode when an ablation area is determined, so as to apply ablation energy to the ablation area, and acquiring physiological parameters in the process of providing the ablation signal to the target electrode; And according to the changing trend of the physiological parameters and the preset benchmark threshold, the ablation category corresponding to the ablation area is determined; when the ablation category is determined to be the recommended ablation category, the ablation signal continues to be provided to the target electrode to ablate the ablation area; wherein the ablation category includes a recommended ablation category and a category not requiring ablation, and the target electrode is one of the multiple electrodes.

11. An ablation control device, characterized in that: include: A signal providing module, configured to provide an ablation signal to a target electrode when an ablation area is determined, so as to apply ablation energy to the ablation area; A parameter acquisition module, used for acquiring physiological parameters in the process of providing the ablation signal to the target electrode; wherein the physiological parameters are physiological parameters of the target electrode under the action of the ablation signal; A judgment module, configured to determine an ablation category corresponding to the ablation area according to a change trend of the physiological parameter and a preset reference threshold, wherein the ablation category includes a recommended ablation category and a no-ablation category; The control module is configured to, when determining that the ablation category is the recommended ablation category, continue to provide an ablation signal to the target electrode to ablate the ablation area.

12. A computer device comprising a memory and a processor, wherein the memory stores a computer program, characterized in that: When the processor executes the computer program, the steps of the method according to any one of claims 1 to 9 are implemented.

13. A computer-readable storage medium having a computer program stored thereon, characterized in that: When the computer program is executed by a processor, the steps of the method according to any one of claims 1 to 9 are implemented.

14. A computer program product comprising a computer program, characterized in that When the computer program is executed by a processor, the steps of the method according to any one of claims 1 to 9 are implemented.

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