Production device for fluorouracil raw material and use method of production device

Abstract

The invention belongs to the technical field of fluorouracil raw materials, and discloses a production device for a fluorouracil raw material and a use method thereof.The production device comprises a reaction kettle body and a separation barrel, the separation barrel is arranged on one side of the reaction kettle body, a hopper is arranged at the top of the reaction kettle body, a feeding pipe is arranged at the top of the hopper, and an introduction pipe is arranged on one side of the separation barrel; a covering plate is arranged at the top of the separation barrel, a screening assembly is arranged in the separation barrel and comprises two bottom plates, two attaching plates, two displacement plates, a screening frame, a first screening net, a separation ring and a second screening net, and the two bottom plates and the two screening nets are mixed to react and then are guided into the separation barrel through an introduction pipe to be separated; and the screening frame and the separation ring are driven to move up and down in the separation barrel, so that the contact area of a mixture with the first screening net and the second screening net is increased, the screening quality of particle impurities in the mixture is improved, and it is ensured that a final reactant has uniform particle size and purity.

Description

Technical Field

[0001] The present invention belongs to the technical field of fluorouracil raw materials, and specifically relates to a production device for fluorouracil raw materials and a method for using the same. Background Art

[0002] The main raw materials of fluorouracil include uracil and fluorinating agent. These raw materials are combined through chemical reaction in the synthesis process to generate fluorouracil. Usually, reaction kettles and separation equipment are required to produce and process fluorouracil. The reaction kettle needs to be made of high temperature and corrosion resistant materials to withstand the high temperature and chemical corrosion that may be generated during the reaction. The separation equipment is equipped with a filter inside to separate unqualified particles, impurities and unreacted raw materials from the fluorouracil generated by the reaction.

[0003] However, the existing production device for fluorouracil raw materials and the use method thereof are not perfect and still have certain defects:

[0004] The filter installed inside the production device is in a static state, and the contact area between the mixture and the filter is not comprehensive, which will reduce the quality of the mixture screening. Impurities that are not removed will be mixed into the final product, affecting its purity and quality. When fluorouracil raw materials are produced, the fluidity is poor, which will delay the production speed. Summary of the invention

[0005] The object of the present invention is to provide a production device for fluorouracil raw materials and a method for using the same to solve the problems raised in the above-mentioned background technology.

[0006] In order to achieve the above-mentioned purpose, the present invention provides the following technical solutions: a production device for fluorouracil raw materials, comprising a reactor body and a separation cylinder, wherein the separation cylinder is arranged on one side of the reactor body, a hopper is arranged on the top of the reactor body, a feed pipe is arranged on the top of the hopper, an introduction pipe is arranged on one side of the separation cylinder, a covering plate is arranged on the top of the separation cylinder, a servo motor is arranged on the top of the covering plate, a screening assembly is arranged inside the separation cylinder, the screening assembly comprises two bottom plates, two bonding plates, two displacement plates, a screening frame, a first screening net, a separation ring and a second screening net, a stirring assembly is arranged inside the separation cylinder, the stirring assembly comprises two support rods, two support blocks, two L-shaped blocks, two vertical bars and a plurality of stirring bars, a cleaning assembly is arranged inside the separation cylinder, the cleaning assembly comprises an auxiliary ferrule, two L-shaped plates and a plurality of scraping bars

[0007] Preferably, a plurality of pressure-resistant seats are provided at the bottom of the reactor body, one end of the introduction pipe is connected to the bottom of the reactor body through an insertion, a guide pipe is provided on the other side of the separation cylinder, the tops of the two bottom plates are respectively fixedly connected to the bottom of the covering plate, and the two bonding plates are respectively located on one side of the two bottom plates.

[0008] Preferably, limiting blocks are provided on both sides of the two bonding plates, arc plates are provided at the bottom ends of the two bonding plates, auxiliary strips are provided inside the two arc plates, one end of the two auxiliary strips is sleeved with moving strips, and one side of the two displacement plates is fixedly connected to one end of the two moving strips respectively.

[0009] Preferably, the two bottom plates are threadedly connected to the four limit blocks by limit bolts respectively, the second spring is wound around the outside of the two auxiliary strips, the top of the screening frame is fixedly connected to the bottom ends of the two displacement plates, the first screening net is arranged inside the screening frame, and the separation ring is arranged at the bottom of the screening frame.

[0010] Preferably, the second screening net is arranged inside the separation circle, one end of the two second springs is fixedly connected to the bottom ends of the two moving bars respectively, the output shaft of the servo motor is transmission-connected with a transmission rod, the auxiliary ring is sleeved on one end of the transmission rod, and one side of the two L-shaped plates is fixedly connected to the two sides of the auxiliary ring respectively.

[0011] Preferably, the two support rods are respectively arranged inside the two L-shaped plates, the two support blocks are respectively movably mounted on one end of the two support rods, the top ends of the two L-shaped blocks are respectively fixedly connected to the bottom ends of the two support blocks, one ends of the two vertical bars are respectively movably connected to the bottoms of the two L-shaped blocks, and the first spring is wrapped around the outside of the two support rods.

[0012] Preferably, one end of the two first springs is respectively fixedly connected to one side of the two support blocks, one end of the two vertical bars is threaded with a limit nut, one end of the multiple stirring bars is respectively fixedly connected to the outer walls of the two vertical bars, and one end of the multiple scraping bars is respectively fixedly and interlacedly connected to one side of the two L-shaped plates.

[0013] A method for using a production device for a fluorouracil raw material, comprising the following steps:

[0014] The first step: injecting the fluorinating agent and uracil into the interior of the reactor through a feed pipe, wherein the fluorinating agent is hydrogen fluoride, and with the help of a catalyst, fluorine atoms are introduced into the ring structure of uracil;

[0015] Step 2: The fluorinating agent is transported to the inside of the screening frame under the action of gravity. The mixture is neutralized to remove excess fluorinating agent. The fluorinating agent is introduced into the separation cylinder through the introduction tube to separate the product. The aperture of the first screening net is larger than that of the second screening net. The second screening net can remove finer unqualified particles and impurities. The moving bar moves up and down at one end of the auxiliary bar. The second spring is compressed and deformed when it is stressed, driving the screening frame and the separation ring to move up and down inside the separation cylinder, increasing the contact area between the mixture and the first screening net and the second screening net, ensuring that the final reactant has a uniform particle size and purity;

[0016] Step 3: After starting the servo motor, the transmission rod connected to its output shaft is driven to rotate, which also drives the auxiliary ring and two L-shaped plates set with it to rotate synchronously. Multiple stirring bars, connected by vertical bars, will make circular motion inside the screening frame. Multiple stirring bars can stir the mixture inside the screening frame to separate the particles and impurities more comprehensively.

[0017] Step 4: As the auxiliary ring rotates, the two L-shaped plates rotate accordingly, and one end of the multiple scraping strips scrape against the inner surface of the first screening net, thereby scraping off the particles and impurities attached to its surface, removing impurities and improving the purity of fluorouracil.

[0018] The beneficial effects of the present invention are as follows:

[0019] 1. The present invention cooperates with the bottom plate, arc plate, auxiliary strip, displacement plate, screening frame, first screening net, separation circle and second screening net to inject the fluorinating agent and uracil into the interior of the reactor body through the feed pipe. After the two are mixed and reacted, they are guided to the interior of the separation cylinder for separation by the introduction pipe. The mixture enters the interior of the screening frame. The aperture of the first screening net is larger than the aperture of the second screening net. The two are used in combination to screen the mixture twice. The second screening net can remove finer unqualified particles and impurities. During the screening process, the moving strip will move up and down at one end of the auxiliary strip, and the second spring will be compressed and deformed when it is stressed, driving the screening frame and the separation circle to move up and down in the separation cylinder, increasing the contact area between the mixture and the first screening net and the second screening net, improving the quality of screening of particulate impurities in the mixture, and ensuring that the final reactant has a uniform particle size and purity.

[0020] 2. The present invention cooperates with the servo motor, auxiliary ring, support rod, support block, vertical bar, stirring bar and limit nut. After the mixture enters the separation cylinder, the servo motor is started to drive the transmission rod connected to its output shaft to rotate, which also drives the auxiliary ring and two L-shaped plates fixedly mounted thereon to rotate synchronously. The support block can move left and right at one end of the support rod. Under the connection of the L-shaped block, it will drive the vertical bar to move synchronously. Under the connection of the vertical bars, multiple stirring bars will make circular motion inside the screening frame. The multiple stirring bars can stir the mixture inside the screening frame to separate the particles and impurities more comprehensively.

[0021] 3. The present invention cooperates with the limit block, the limit bolt, the L-shaped plate, the scraper bar, the first spring, the moving bar and the second spring to rotate the corresponding two limit bolts in the opposite direction, so that the two limit bolts are separated from the bottom plate respectively, and the arc plate and the cover plate can be separated, which is convenient for cleaning the first screening net and the second screening net. During the rotation of the transmission rod, one end of the multiple scrapers rubs against the inner surface of the first screening net respectively, so that the particles and impurities attached to the surface can be scraped off, avoiding the blockage of the first screening net and affecting the subsequent screening of particles and impurities, removing impurities and improving the purity of fluorouracil. The limit nut is rotated in the opposite direction, and the vertical bar is pulled downward to separate the vertical bar from the L-shaped block, which is convenient for replacing a new stirring bar. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 It is a front view structural schematic diagram of the present invention;

[0023] Figure 2 It is a partial front view structural schematic diagram of the present invention;

[0024] Figure 3 For the present invention Figure 1 The enlarged view of point A in the middle;

[0025] Figure 4 It is a partial side view structural schematic diagram of the present invention;

[0026] Figure 5 It is a partial top view structural schematic diagram of the present invention;

[0027] Figure 6 For the present invention Figure 5 Enlarged view of point B in the middle.

[0028] In the figure: 1. Reactor body; 2. Hopper; 3. Feed pipe; 4. Separation cylinder; 5. Inlet pipe; 6. Guide pipe; 7. Anti-pressure seat; 8. Cover plate; 9. Servo motor; 10. Transmission rod; 11. Auxiliary ring; 12. L-shaped plate; 13. Scraper bar; 14. Support rod; 15. Support block; 16. L-shaped block; 17. Vertical bar; 18. Stirring bar; 19. Limit nut; 20. First spring; 21. Bottom plate; 22. Fitting plate; 23. Limit block; 24. Limit bolt; 25. Arc plate; 26. Auxiliary bar; 27. Moving bar; 28. Displacement plate; 29. ​​Screening frame; 30. First screening net; 31. Second spring; 32. Separation ring; 33. Second screening net. DETAILED DESCRIPTION

[0029] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0030] like Figures 1 to 6 As shown, the embodiment of the present invention provides a technical solution for a production device for fluorouracil raw materials and a method for using the same:

[0031] Embodiment 1:

[0032] like Figure 1-2As shown, a production device for fluorouracil raw materials includes a reactor body 1 and a separation cylinder 4, the separation cylinder 4 is arranged on one side of the reactor body 1, a hopper 2 is arranged on the top of the reactor body 1, a feed pipe 3 is arranged on the top of the hopper 2, an introduction pipe 5 is arranged on one side of the separation cylinder 4, a cover plate 8 is arranged on the top of the separation cylinder 4, a servo motor 9 is arranged on the top of the cover plate 8, a screening component is arranged inside the separation cylinder 4, the screening component includes two bottom plates 21, two bonding plates 22, two displacement plates 28, a screening frame 29, a first screening net 30, a separation ring 32 and a second screening net 33, and a stirring component is arranged inside the separation cylinder 4, the stirring component includes two support rods 14, two support blocks 15, two L-shaped blocks 16, two vertical bars 17 and multiple stirring bars 18. A cleaning component is arranged inside the separation cylinder 4, and the cleaning component includes an auxiliary ring 11, two L-shaped plates 12 and multiple scraping bars 13. The second screening net 33 can remove finer unqualified particles and impurities. During the screening process, the moving bar 27 will move up and down at one end of the auxiliary bar 26, and the second spring 31 will be compressed and deformed when subjected to force, driving the screening frame 29 and the separation ring 32 to move up and down inside the separation cylinder 4, increasing the contact area between the mixture and the first screening net 30 and the second screening net 33, improving the quality of screening of particulate impurities in the mixture, and ensuring that the final reactant has a uniform particle size and purity.

[0033] Embodiment 2:

[0034] Based on the first embodiment, Figure 2-5 As shown, limit blocks 23 are provided on both sides of the two laminating plates 22, and arc plates 25 are provided at the bottom ends of the two laminating plates 22. Auxiliary bars 26 are provided inside the two arc plates 25, and one end of the two auxiliary bars 26 is sleeved with a moving bar 27. One side of the two displacement plates 28 is fixedly connected to one end of the two moving bars 27 respectively. The present invention cooperates with the servo motor 9, auxiliary ring 11, support rod 14, support block 15, vertical bar 17, stirring bar 18 and limit nut 19. After the mixture enters the separation cylinder 4, the servo motor 9 is started to drive the transmission rod 10 connected to its output shaft to rotate, which also drives the auxiliary ring 11 and the two L-shaped plates 12 fixedly sleeved therewith to rotate synchronously. The support block 15 can move left and right at one end of the support rod 14, and under the connection of the L-shaped block 16, it will drive the vertical bar 17 to move synchronously.

[0035] Embodiment three:

[0036] On the basis of the first and second embodiments, Figure 1 and Figure 6As shown, the second screening net 33 is arranged inside the separation circle 32, one end of the two second springs 31 is fixedly connected to the bottom end of the two moving bars 27, the output shaft of the servo motor 9 is connected to the transmission rod 10, the auxiliary ring 11 is sleeved on one end of the transmission rod 10, one side of the two L-shaped plates 12 is fixedly connected to the two sides of the auxiliary ring 11, the two support rods 14 are arranged inside the two L-shaped plates 12, the two support blocks 15 are movably sleeved on one end of the two support rods 14, the top ends of the two L-shaped blocks 16 are fixedly connected to the bottom ends of the two support blocks 15, and one end of the two vertical bars 17 is respectively connected to The bottoms of the two L-shaped blocks 16 are movably connected and interlaced, and the outsides of the two support rods 14 are both wound with the first springs 20. The present invention cooperates with the set limit block 23, the limit bolt 24, the L-shaped plate 12, the scraper strip 13, the first spring 20, the moving strip 27 and the second spring 31 to rotate the corresponding two limit bolts 24 in the opposite direction, so that the two limit bolts 24 are respectively separated from the bottom plate 21, and the arc plate 25 and the covering plate 8 can be separated, which is convenient for cleaning the first screening net 30 and the second screening net 33. During the rotation of the transmission rod 10, one end of the plurality of scraper strips 13 rubs against the inner surface of the first screening net 30 respectively.

[0037] A method for using a production device for a fluorouracil raw material, comprising the following steps:

[0038] The first step: injecting a fluorinating agent and uracil into the interior of the reactor body 1 through a feed pipe 3, wherein the fluorinating agent is hydrogen fluoride, and with the help of a catalyst, fluorine atoms are introduced into the ring structure of uracil;

[0039] Step 2: The fluorinating agent is transported to the inside of the screening frame 29 under the action of gravity, and the mixture is neutralized to remove excess fluorinating agent. The fluorinating agent is introduced into the inside of the separation cylinder 4 through the introduction pipe 5 to separate the product. The aperture of the first screening net 30 is larger than the aperture of the second screening net 33. The second screening net 33 can remove finer unqualified particles and impurities. The moving bar 27 moves up and down at one end of the auxiliary bar 26, and the second spring 31 is compressed and deformed when it is stressed, driving the screening frame 29 and the separation ring 32 to move up and down in the separation cylinder 4, increasing the contact area between the mixture and the first screening net 30 and the second screening net 33, ensuring that the final reactant has a uniform particle size and purity;

[0040] Step 3: After the servo motor 9 is started, the transmission rod 10 connected to its output shaft is driven to rotate, which also drives the auxiliary ring 11 and the two L-shaped plates 12 mounted thereon to rotate synchronously. The plurality of stirring bars 18, connected with the vertical bars 17, will make a circular motion inside the screening frame 29. The plurality of stirring bars 18 can stir the mixture inside the screening frame 29, so that the particles and impurities are separated more comprehensively.

[0041] Step 4: As the auxiliary ring 11 rotates, the two L-shaped plates 12 rotate accordingly, and one end of the plurality of scraping strips 13 scrapes against the inner surface of the first screening net 30, thereby scraping off the particles and impurities attached to the surface, removing the impurities and improving the purity of fluorouracil.

[0042] The working principle and use process of the present invention are as follows: the main raw materials of fluorouracil include uracil and a fluorinating agent. These raw materials are combined by chemical reaction during the synthesis process to generate fluorouracil. Usually, a reactor and a separation device are required to produce and process fluorouracil. The reactor needs to be made of high-temperature resistant and corrosion-resistant materials to withstand the high temperature and chemical corrosion generated during the reaction. A filter is provided inside the separation device to separate unqualified particles, impurities and unreacted raw materials from the fluorouracil generated by the reaction. The fluorinating agent and uracil are injected into the interior of the reactor body 1 through the feed pipe 3. After the two are mixed and reacted, they are guided to the interior of the separation cylinder 4 by the introduction pipe 5 for separation. The mixture enters the interior of the screening frame 29. The aperture of the first screening net 30 is larger than the aperture of the second screening net 33. The two are used in combination to screen the mixture twice. The second screening net 33 can remove finer unqualified particles and impurities. During the screening process, the moving bar 27 will move up and down at one end of the auxiliary bar 26, and the second spring 31 will be compressed and deformed when it is stressed, driving the screening frame 29 and the separation circle 32 to move up and down inside the separation cylinder 4, increasing the contact area between the mixture and the first screening net 30 and the second screening net 33, improving the quality of screening of particulate impurities in the mixture, ensuring that the final reactant has a uniform particle size and purity, and the mixture enters After entering the separation cylinder 4, the servo motor 9 is started to drive the transmission rod 10 connected to its output shaft to rotate, which also drives the auxiliary ring 11 and the two L-shaped plates 12 fixed thereto to rotate synchronously. The support block 15 can move left and right at one end of the support rod 14. Under the connection of the L-shaped block 16, the vertical bar 17 will be driven to move synchronously, increasing the range of stirring of the mixture by the multiple stirring bars 18. Under the connection of the vertical bar 17, the multiple stirring bars 18 will make a circular motion inside the screening frame 29. The multiple stirring bars 18 can stir the mixture inside the screening frame 29, so that the particles and impurities are separated more comprehensively, and the corresponding two stirring bars 18 are rotated in the opposite direction. The limiting bolts 24 are used to separate the two limiting bolts 24 from the bottom plate 21, so that the arc plate 25 and the covering plate 8 can be separated, which is convenient for cleaning the first screening net 30 and the second screening net 33. During the rotation of the transmission rod 10, one end of the multiple scraping bars 13 rubs against the inner surface of the first screening net 30, so that the particles and impurities attached to the surface can be scraped off, avoiding the blockage of the first screening net 30 and affecting the subsequent screening of particles and impurities, removing impurities and improving the purity of fluorouracil. The limiting nut 19 is rotated in the opposite direction, and the vertical bar 17 is pulled downward to separate the vertical bar 17 from the L-shaped block 16, so as to facilitate the replacement of a new stirring bar 18.

[0043] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A production device for fluorouracil raw materials, comprising a reaction vessel (1) and a separation cylinder (4), wherein the separation cylinder (4) is arranged on one side of the reaction vessel (1), characterized in that: A hopper (2) is arranged on the top of the reaction kettle body (1), a feed pipe (3) is arranged on the top of the hopper (2), an inlet pipe (5) is arranged on one side of the separation cylinder (4), a cover plate (8) is arranged on the top of the separation cylinder (4), a servo motor (9) is arranged on the top of the cover plate (8), a screening assembly is arranged inside the separation cylinder (4), and the screening assembly comprises two bottom plates (21), two bonding plates (22), two displacement plates (28), a screening frame (29), a first screening net (30), a separation ring (32) and a second screening net (33); a stirring assembly is arranged inside the separation cylinder (4), and the stirring assembly includes two support rods (14), two support blocks (15), two L-shaped blocks (16), two vertical bars (17) and a plurality of stirring bars (18); a cleaning assembly is arranged inside the separation cylinder (4), and the cleaning assembly includes an auxiliary ring (11), two L-shaped plates (12) and a plurality of scraping bars (13).

2. The production device for fluorouracil raw materials according to claim 1, characterized in that: A plurality of pressure-resistant seats (7) are provided at the bottom of the reactor body (1), one end of the introduction pipe (5) is connected to the bottom of the reactor body (1) through insertion, a guide pipe (6) is provided on the other side of the separation cylinder (4), the tops of the two bottom plates (21) are respectively fixedly connected to the bottom of the covering plate (8), and the two bonding plates (22) are respectively located on one side of the two bottom plates (21).

3. The production device for fluorouracil raw materials according to claim 2, characterized in that: Limiting blocks (23) are arranged on both sides of the two bonding plates (22), arc plates (25) are arranged at the bottom ends of the two bonding plates (22), auxiliary strips (26) are arranged inside the two arc plates (25), one end of the two auxiliary strips (26) is sleeved with a moving strip (27), and one side of the two displacement plates (28) is fixedly connected to one end of the two moving strips (27) respectively.

4. The production device for fluorouracil raw materials according to claim 3, characterized in that: The two bottom plates (21) are respectively threadedly connected to the four limit blocks (23) via limit bolts (24); the second spring (31) is wound around the outside of the two auxiliary strips (26); the top of the screening frame (29) is fixedly connected to the bottom ends of the two displacement plates (28); the first screening net (30) is arranged inside the screening frame (29); and the separation ring (32) is arranged at the bottom of the screening frame (29).

5. The production device for fluorouracil raw materials according to claim 4, characterized in that: The second screening net (33) is arranged inside the separation ring (32), one end of the two second springs (31) is fixedly connected to the bottom ends of the two moving bars (27), the output shaft of the servo motor (9) is connected to the transmission rod (10), the auxiliary ring (11) is sleeved on one end of the transmission rod (10), and one side of the two L-shaped plates (12) is fixedly connected to the two sides of the auxiliary ring (11).

6. The production device for fluorouracil raw materials according to claim 1, characterized in that: The two support rods (14) are respectively arranged inside the two L-shaped plates (12); the two support blocks (15) are respectively movably mounted on one end of the two support rods (14); the top ends of the two L-shaped blocks (16) are respectively fixedly connected to the bottom ends of the two support blocks (15); one ends of the two vertical bars (17) are respectively movably connected to the bottoms of the two L-shaped blocks (16); and the outsides of the two support rods (14) are both wound with a first spring (20).

7. The production device for fluorouracil raw materials according to claim 6, characterized in that: One end of the two first springs (20) is respectively fixedly connected to one side of the two support blocks (15), one end of the two vertical bars (17) is threadedly sleeved with a limit nut (19), one end of the plurality of stirring bars (18) is respectively fixedly connected to the outer wall of the two vertical bars (17), and one end of the plurality of scraping bars (13) is respectively fixedly connected to one side of the two L-shaped plates (12).

8. A method for using a production device for fluorouracil raw materials, the method being applicable to the production device for fluorouracil raw materials described in claims 1 to 7, characterized in that : Includes the following steps: The first step is to inject a fluorinating agent and uracil into the interior of the reaction vessel (1) through a feed pipe (3), wherein the fluorinating agent is hydrogen fluoride, and with the help of a catalyst, fluorine atoms are introduced into the ring structure of uracil; Step 2: The fluorinating agent is transported to the inside of the screening frame (29) under the action of gravity. The mixture is neutralized to remove excess fluorinating agent. The fluorinating agent is introduced into the inside of the separation cylinder (4) through the introduction pipe (5) to separate the product. The aperture of the first screening net (30) is larger than the aperture of the second screening net (33). The second screening net (33) can remove finer unqualified particles and impurities. The moving bar (27) moves up and down at one end of the auxiliary bar (26). The second spring (31) is compressed and deformed when subjected to force, driving the screening frame (29) and the separation ring (32) to move up and down inside the separation cylinder (4), thereby increasing the contact area between the mixture and the first screening net (30) and the second screening net (33), thereby ensuring that the final reactant has a uniform particle size and purity. Step 3: After the servo motor (9) is started, the transmission rod (10) connected to the output shaft thereof is driven to rotate, thereby driving the auxiliary ring (11) and the two L-shaped plates (12) mounted thereon to rotate synchronously. The plurality of stirring bars (18) connected to the vertical bars (17) will make a circular motion inside the screening frame (29). The plurality of stirring bars (18) can stir the mixture inside the screening frame (29) so that the particles and impurities are separated more comprehensively. Step 4: As the auxiliary ring (11) rotates, the two L-shaped plates (12) rotate accordingly, and one end of a plurality of scraping strips (13) scrapes against the inner surface of the first sieve net (30), thereby scraping off particles and impurities attached to the surface, removing impurities and improving the purity of fluorouracil.

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