Personal cleansing composition free of surfactants of alkyl sulfate or alkyl ether sulfate type

Abstract

A personal cleansing composition comprises a surfactant system, wherein the surfactant system comprises: from 0.1% to 5% by weight of the composition of a fatty acyl isethionate surfactant; from 0.5% to 40% by weight of the composition of a co-surfactant; wherein the composition is free of surfactants of the alkyl sulfate or alkyl ether sulfate type; from 0.05% to 5% by weight of the composition of a nonionic surfactant, wherein the nonionic surfactant comprises a fatty alkanolamide; from 0.01% to 2.0%, by weight of the composition, of a hydrophobically modified ethoxylated methyl glucoside; 0.01% to 1.0%, by weight of the composition, of a preservative; and wherein the pH is from 5.5 to 7.

Description

Technical Field

[0001] The present application is generally directed to personal cleansing compositions having increased stability in terms of phase, color and microbial stability, methods thereof and uses thereof. The personal cleansing composition comprises a surfactant system, wherein the surfactant system comprises a fatty acyl isethionate surfactant, and wherein the personal cleansing composition is free of alkyl sulfate or alkyl ether sulfate type surfactants. Background Art

[0002] Personal cleansing compositions are traditionally sold in a variety of forms, such as bar soaps, creams, lotions, and gels. Typically, these products must meet a number of criteria that are acceptable to consumers. These criteria include cleaning effectiveness, skin feel, mildness to the skin, hair, and ocular mucosa, and foam volume. An ideal personal cleanser should gently clean the skin or hair, cause little or no irritation, and should not overdry the skin or hair after frequent use.

[0003] Anionic surfactants are widely used in personal cleansing compositions. Many of these anionic surfactants contain elongated micelles and are viscoelastic, which is very important, especially in the design of shampoos and body washes. In most personal cleansing compositions, alkyl sulfates or alkyl ether sulfates predominate as anionic surfactants.

[0004] The formulation of environmentally friendly personal cleansing compositions is becoming a major challenge to meet the new expectations of consumers, especially towards eco-designed and / or natural products. There is a need to propose personal cleansing compositions free of alkyl sulfates and alkyl ether sulfates, which have good cosmetic qualities, mainly in terms of viscosity, creamy foam, clean skin feel.

[0005] Consumers prefer sulfate-free personal cleansing compositions due to perceived mildness and desirable sensory experience.It would be desirable to provide personal cleansing products comprising alternative mild surfactant systems having relatively improved ecotoxicity or eco-friendly environmental characteristics.

[0006] Personal cleansing compositions have been developed having a surfactant system comprising a fatty acyl isethionate surfactant and being free of alkyl sulfate or alkyl ether sulfate type surfactants. Fatty acyl isethionates are highly desirable mild anionic surfactants in personal cleansing products for hair or skin because fatty acyl isethionates lather well, are mild to the skin, and have good emollient properties.

[0007] However, fatty acyl isethionates may result in unstable personal cleansing compositions that may exhibit inconsistent rheological characteristics. Phase separation has been observed for personal cleansing compositions containing fatty acyl isethionates and a fragrance component after storage at 40°C for 3 months. The phase separation may be attributed to the presence of hydrophobic molecules in the fragrance component or fatty acids that have been generated by the hydrolysis of the fatty acyl isethionates. The initial worm-like and spherical micellar compositions may separate into an upper lamellar phase and a lower micellar phase. The lamellar phase is typically a relatively highly ordered surfactant-rich phase that has relatively little water and a low density, making the lamellar phase buoyant.

[0008] Therefore, there is a need to provide personal cleansing compositions comprising fatty acyl isethionate surfactants, free of alkyl sulfate or alkyl ether sulfate type surfactants, and having improved phase stability and a satisfactorily consistent rheological profile.

[0009] There is a need to provide personal cleansing compositions comprising fatty acyl isethionate surfactants, free of alkyl sulfate or alkyl ether sulfate type surfactants, and having acceptable or improved stability with respect to color and antimicrobial stability.

[0010] Additionally, there remains a need for personal cleansing compositions that clean effectively even when containing lower amounts of active surfactants than typical cleansing products, yet also have good aesthetic properties such as good lather, and are thick and creamy in texture, silky to the touch, and provide a conditioning benefit. Summary of the invention

[0011] Provided is a personal cleansing composition comprising:

[0012] a) a surfactant system, wherein the surfactant system comprises:

[0013] (i) from 0.1% to 5%, preferably from 0.5% to 4%, more preferably from 1% to 3%, most preferably from 1.5% to 2.5% by weight of the composition of a fatty acyl isethionate surfactant;

[0014] (ii) from 0.5% to 40%, preferably from 1% to 25%, more preferably from 5% to 15%, most preferably from 5.5% to 8.0%, by weight of the composition, of a co-surfactant;

[0015] wherein the composition does not contain surfactants of the alkyl sulfate or alkyl ether sulfate type;

[0016] b) from 0.05% to 5%, preferably from 0.1% to 2%, more preferably from 0.5% to 1.5%, most preferably from 0.75% to 1.0%, by weight of the composition, of a nonionic surfactant, wherein the nonionic surfactant comprises a fatty alkanolamide;

[0017] c) from 0.01% to 2.0%, preferably from 0.05% to 1.5%, more preferably from 0.07% to 0.50%, most preferably from 0.1% to 0.15%, by weight of the composition, of a hydrophobically modified ethoxylated methyl glucoside;

[0018] d) from 0.01% to 1.0%, preferably from 0.02% to 0.4%, more preferably from 0.05% to 0.2%, most preferably from 0.05% to 0.1% by weight of the composition of a preservative; and

[0019] e) wherein the pH is from 5.5 to 7, preferably from 5.5 to 6.5, more preferably from 5.6 to 6.1.

[0020] A method for increasing the stability of a personal cleansing composition with respect to phase, color and microbial stability is provided and comprises the steps of forming a personal cleansing composition as described hereinafter. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] While the specification concludes with a description particularly pointing out and distinctly claiming the invention, it is believed that the invention will be better understood from the following description when read in conjunction with the accompanying drawings, wherein:

[0022] Figure 1 is a graph showing the effect of thickeners and their relative concentrations on enhancing the viscosity of a personal cleansing composition; and

[0023] Figure 2 is a graph showing the effect of a thickening system on enhancing the viscosity of a personal cleansing composition at different levels of electrolyte (sodium chloride). DETAILED DESCRIPTION

[0024] Definition of terms

[0025] In this document, unless specifically stated otherwise, the following definitions apply in all embodiments, including in all aspects of the invention.

[0026] Unless otherwise specified, all percentages are by weight (w / w) of the composition. "Wt. %" means weight percentage. References to "parts" (e.g., a mixture of 1 part X and 3 parts Y) are ratios by weight. Unless otherwise specifically specified, all ratios or percentages are weight ratios or weight percentages.

[0027] An "active composition" is a composition that does not contain water, and an "active ingredient" is an ingredient that does not contain water.

[0028] "QS" or "QSP" means sufficient quantity for 100% or for 100 g. + / - indicates standard deviation. All ranges are inclusive and combinable. The number of significant figures expresses neither a limitation on the amount shown nor a limitation on the accuracy of the measurement. All numerical values ​​are understood to be modified by the word "about".

[0029] Unless otherwise indicated, all measurements are understood to be made at 25°C and ambient conditions, where "ambient conditions" means at a pressure of 1 atmosphere (atm) and at 65% relative humidity. "Relative humidity" means the ratio of the moisture content of air compared to the saturation moisture content at the same temperature and pressure (expressed as a percentage). Relative humidity can be measured using a hygrometer, specifically using a hygrometer obtained from International probe moisture meter.

[0030] "Min" herein means "min" or "several minutes". "Mol" herein means "mole". "G" after a number herein means "gram". "Ex." means "Example". All amounts referring to listed ingredients are based on the active substance content and do not include carriers or by-products that may be contained in commercially available materials.

[0031] As used herein, "comprising" means that other steps and other ingredients may be added. "Comprising" encompasses the terms "consisting of" and "consisting essentially of." The compositions, methods, uses and processes of the invention may comprise, consist of and consist essentially of the elements and limitations of the invention described herein, as well as any additional or optional ingredients, components, steps or limitations described herein. Unless incompatibility is indicated, the embodiments and aspects described herein may include elements, features or components of other embodiments and / or aspects or may be combined with elements, features or components of other embodiments and / or aspects, although not explicitly exemplified in combination.

[0032] As used herein, articles including "a", "an", and "an" when used in a claim should be understood to mean one or more of what is claimed or described.

[0033] As used herein, the terms "including," "comprising," and "containing" are intended to be non-limiting.

[0034] Where content ranges are given, these should be understood to be the total amount of the ingredient in the composition, or where more than one material falls within an ingredient definition, the total amount of all ingredients in the composition that meet the definition.

[0035] For example, if a composition comprises 1% to 5% fatty alcohol, a composition comprising 2% stearyl alcohol and 1% cetyl alcohol and no other fatty alcohols would fall within the range.

[0036] The amount of each specific ingredient or mixtures thereof described below may comprise up to 100% (or 100%) of the total amount of ingredients in the composition.

[0037] As used herein, the term "free of" means that the composition comprises 0% of an ingredient by weight of the composition and thus has no detectable amount of the ingredient.

[0038] As used herein, the term "substantially free" means less than 1%, less than 0.8%, less than 0.5%, less than 0.3%, or less than an insubstantial amount by weight of the composition.

[0039] Herein, "Comp. Ex." or "C. Ex." means "Comparative Example"; and "Ex." means "Example".

[0040] Unless otherwise indicated, as used herein, the term "molecular weight" or "M.Wt." refers to weight average molecular weight. Weight average molecular weight can be measured by gel permeation chromatography ("GPC").

[0041] As used herein, the term "personal cleansing composition" refers to compositions intended for topical application to the hair and skin, preferably the skin, for cleansing.

[0042] As used herein, the term "mixture" is meant to include a simple combination of substances, as well as any compounds that may result from their combination.

[0043] The term "room temperature" refers to a temperature of 25°C.

[0044] As used herein, the term "rinse-off" means that the intended use of the product includes application to the skin and then washing and / or wiping the product from the skin within seconds to minutes of the application step. The product is usually applied and rinsed in the same use event, such as showering or washing hands.

[0045] As used herein, the term "derivative" refers to a structure not shown but understood by one skilled in the art to be a variation of the basic compound.

[0046] The methods as disclosed herein are cosmetic or non-therapeutic methods.

[0047] The object of the present invention is to provide a personal cleaning product, method and use of the product, structure and corresponding composition as described in the summary of the invention or as described below for achieving the technical effects or goals as set forth herein. These objectives and other advantages described in the above summary of the invention and the detailed description and defined in the subsequent claims that can be obtained by the present invention may be obvious to those skilled in the art.

[0048] Beneficial Effects

[0049] Personal cleansing compositions containing fatty acyl isethionates have been observed to phase separate after storage at 40°C for 3 months (see Comparative Example 1 for an example). The mechanism of phase separation may lie in the hydrolysis of fatty acyl isethionates catalyzed by other anionic surfactants such as fatty acyl sarcosinates in acidic media (e.g., pH 5).

[0050] Increasing the pH will slow down the hydrolysis kinetics, however, at neutral pH, the zero shear viscosity of the personal cleansing composition may collapse. Without the addition of any electrolytes, only a small portion of the anionic surfactant (e.g., fatty acyl sarcosinate) in deprotonated form is required to form a stable worm-like micellar phase. The pH of the personal cleansing composition cannot be raised above the pKa of the anionic surfactant, otherwise, the viscosity peak will be lost and the personal cleansing composition will not meet the rheological characteristics.

[0051] Because of the need to increase pH in order to control the hydrolysis kinetics of fatty acyl isethionates, new combinations of ingredients are needed to build a consistent viscosity for personal cleansing compositions.

[0052] It has been found that personal cleansing compositions need to comprise from 0.05% to 5%, preferably from 0.1% to 2%, more preferably from 0.5% to 1.5%, most preferably from 0.75% to 1.0%, by weight of the composition, of a nonionic surfactant, wherein the nonionic surfactant comprises a fatty alkanolamide; and from 0.01% to 2.0%, preferably from 0.05% to 1.5%, more preferably from 0.07% to 0.50%, most preferably from 0.1% to 0.15%, by weight of the composition, of a hydrophobically modified ethoxylated methyl glucoside.

[0053] The desired viscosity of the personal cleansing composition can be achieved by extending the micelles at a higher pH of 5.5 to 7, preferably 5.5 to 6.5, more preferably 5.6 to 6.1.

[0054] The selection of nonionic surfactant and hydrophobically modified ethoxylated methyl glucoside at specific levels and weight ratios is described in more detail below.

[0055] In addition, it has been observed that certain ingredients (e.g., fragrance components with hydrophobic materials) may play a role not only in phase separation, but also in decolorization. Without the addition of any fragrance components, other ingredients (such as nonionic surfactants and hydrophobically modified ethoxylated methyl glucoside) may also cause decolorization of personal cleansing compositions. Therefore, it is necessary to develop suitable preservative systems to provide acceptable or improved color and antimicrobial stability.

[0056] The preservative may be selected from the group consisting of alkali metal metabisulfites, alkali metal sulfites, alkali metal bisulfites, alkali metal dithionites, and mixtures thereof.The preservative may help prevent any discoloration of the personal cleansing composition as well as provide antimicrobial efficacy, as described in detail below.

[0057] Surfactant system

[0058] The present invention provides a personal cleaning composition, which comprises a surfactant system, wherein the surfactant system comprises:

[0059] 0.1% to 5%, preferably 0.5% to 4%, more preferably 1% to 3%, most preferably 1.5% to 2.5% by weight of the composition of a fatty acyl isethionate surfactant;

[0060] 0.5% to 40%, preferably 1% to 25%, more preferably 5% to 15%, most preferably 5.5% to 8.0%, by weight of the composition, of a co-surfactant; and

[0061] Wherein the composition is free of surfactants of the alkyl sulfate and / or alkyl ether sulfate type.

[0062] The personal cleansing composition does not contain surfactants of the alkyl sulfate and / or alkyl ether sulfate type. Preferably, the personal cleansing composition does not contain surfactants having C 12 To C 18 Any alkyl sulfate of alkyl sulfate and / or any alkyl ether sulfate including alkyl glyceryl ether sulfate.

[0063] The personal cleansing composition may not contain any alkyl ether sulfates which are alkyl ether sulfates having the formula:

[0064] RO(CH2CH2O) n SO3M

[0065] wherein R is an alkyl or alkenyl group having 8 to 18 carbons, preferably 12 to 18 carbons, n has an average value greater than at least 0.5, preferably between 2 and 3; and M is a solubilizing cation such as sodium, potassium, ammonium or substituted ammonium.

[0066] The personal cleansing composition may not contain any ammonium lauryl ether sulfate and sodium lauryl ether sulfate.

[0067] If the personal cleansing composition does contain alkyl sulfate and / or alkyl ether sulfate type surfactants, the content of such weight proportions of alkyl sulfate or alkyl ether sulfate type surfactants is less than or equal to the sum of 0.6, more preferably less than or equal to the sum of 0.2, and even more preferably equal to 0.

[0068] Fatty acyl isethionate

[0069] Fatty acyl isethionate surfactants can be defined as isethionates according to the general formula (I):

[0070]

[0071] wherein R1 is a saturated or unsaturated linear or branched alkyl or alkenyl chain having 6 to 30 carbon atoms, preferably 8 to 22 carbon atoms, more preferably 9 to 18 carbon atoms, R2 and R3 are each independently H or (C1-C4) alkyl, and M + is an alkali metal, preferably lithium, sodium, potassium; or M + is an alkaline earth metal, preferably magnesium; or M + is an ammonium or substituted ammonium cation.

[0072] Preferably, R1 can be a saturated or unsaturated linear or branched alkyl or alkenyl chain, preferably an alkyl chain, having 6 to 30 carbon atoms, preferably 8 to 22 carbon atoms, more preferably 9 to 18 carbon atoms, R2 and R3 are H, and M + is an alkali metal, preferably sodium or potassium; or + It is an ammonium cation.

[0073] More preferably, R1 may be a saturated or unsaturated linear or branched alkyl chain having 9 to 18 carbon atoms, R2 and R3 are H, and M + It is a sodium cation or an ammonium cation.

[0074] Suitable fatty acyl isethionate surfactants may include the reaction product of fatty acids esterified with isethionates and neutralized with sodium hydroxide. Suitable fatty acids for isethionate surfactants may be derived from, for example, coconut oil or palm kernel oil. Additional examples of suitable isethionate anionic surfactants are described in U.S. Pat. No. 2,486,921, U.S. Pat. No. 2,486,922, and U.S. Pat. No. 2,396,278, each of which is incorporated herein by reference.

[0075] The fatty acyl isethionate surfactant may be selected from the group consisting of sodium lauroyl isethionate, sodium lauroyl methyl isethionate, sodium oleoyl isethionate, sodium oleoyl methyl isethionate, sodium stearoyl isethionate, sodium stearoyl methyl isethionate, sodium myristoyl isethionate, sodium myristoyl methyl isethionate, sodium palmitoyl isethionate, sodium palmitoyl methyl isethionate, sodium cocoyl isethionate, sodium cocoyl methyl isethionate, a blend of stearic acid and sodium cocoyl isethionate, ammonium cocoyl isethionate, ammonium cocoyl methyl isethionate, and mixtures thereof.

[0076] The fatty acyl isethionate surfactant may preferably be selected from the group consisting of sodium lauroyl isethionate, sodium myristoyl isethionate, sodium palmitoyl isethionate, sodium stearoyl isethionate, sodium oleoyl isethionate, sodium cocoyl isethionate, ammonium cocoyl isethionate and mixtures thereof.

[0077] The fatty acyl isethionate surfactant may more preferably be selected from sodium lauroyl isethionate, sodium cocoyl isethionate, ammonium cocoyl isethionate, and mixtures thereof.

[0078] The corresponding commercial products may be marketed, for example, under the trade name Available from Innospec, and under the trade name or Available from Clariant or Uniquema. Examples of other commercial fatty acyl isethionates that can be used are available from Clariant Surfactants, such as sodium cocoyl isethionate: SCI-85C, SCI-78C, or a blend of stearic acid and sodium cocoyl isethionate: SCI-65C. Examples of other commercial fatty acyl isethionates that can be used are available from BASF Surfactants, such as CI particles or CI65; and sodium cocoyl isethionate from YonganDaily Chemical Co., such as or

[0079] Fatty acyl isethionate surfactants are typically prepared by the reaction of an isethionate salt such as a metal isethionate or ammonium isethionate with a saturated or unsaturated straight or branched alkyl or alkenyl chain fatty acid having from 6 to 30 carbon atoms, preferably from 8 to 22 carbon atoms, more preferably from 6 to 18 carbon atoms. Depending on the processing conditions used, the resulting fatty acyl isethionate surfactant may be a mixture of 45 to 95 wt% fatty acyl isethionate and 0 to 40 wt% free fatty acids, and typically less than 5 wt% isethionate and trace amounts (less than 2 wt%) of other impurities, based on the total weight of the resulting fatty acyl isethionate surfactant. Mixtures of aliphatic fatty acids can be used to prepare commercial fatty acyl isethionate surfactants.

[0080] The personal cleansing composition comprises a surfactant system. The surfactant system comprises from 0.1% to 5%, preferably from 0.5% to 4%, more preferably from 1% to 3%, most preferably from 1.5% to 2.5% of a fatty acyl isethionate surfactant by weight of the composition. Where more than one fatty acyl isethionate surfactant is present, the concentrations referred to herein are total concentration ranges. The specified ranges are provided by weight and relate to the total weight of the personal cleansing composition.

[0081] Fatty acyl sarcosinate

[0082] The surfactant system may further comprise from 0.1% to 10%, preferably from 0.5% to 8%, more preferably from 1% to 5%, most preferably from 3.5% to 5% by weight of the composition of a fatty acyl sarcosinate surfactant.

[0083] The fatty acyl sarcosinate surfactant may be a sarcosinate according to the general formula (II):

[0084]

[0085] wherein R is a saturated or unsaturated linear or branched alkyl or alkenyl chain having 7 to 17 carbon atoms, preferably 9 to 13 carbon atoms, preferably an alkyl chain, and M + It is H, sodium cation, potassium cation or ammonium cation.

[0086] Fatty acyl sarcosinate can be selected from the group consisting of sodium lauroyl sarcosinate, sodium cocoyl sarcosinate, sodium myristoyl sarcosinate, TEA-cocoyl sarcosinate, ammonium cocoyl sarcosinate, ammonium lauroyl sarcosinate, dimer dilinoleyl dilauroyl glutamate / lauroyl sarcosinate, lauroyl sarcosinate, isopropyl lauroyl sarcosinate, potassium cocoyl sarcosinate, potassium lauroyl sarcosinate, sodium oleoyl sarcosinate, sodium palmitoyl sarcosinate, TEA-lauroyl sarcosinate, TEA-oleoyl sarcosinate, TEA-palm kernel sarcosinate and mixtures thereof. For example, TEA-cocoyl sarcosinate is the triethanolamine salt of coconut oil base sarcosine.

[0087] Preferably, the fatty acyl sarcosinate may be selected from sodium lauroyl sarcosinate, sodium myristoyl sarcosinate, sodium cocoyl sarcosinate, and mixtures thereof.

[0088] The weight ratio of fatty acyl isethionate to fatty acyl sarcosinate may be 2:3 to 1:1, preferably 3:4 to 1:1. In this aspect, the phase stability of the personal cleansing composition may be enhanced by further extending the micelles, thereby building the viscosity of the personal cleansing composition.

[0089] Auxiliary surfactant

[0090] The surfactant system comprises from 0.5% to 40%, preferably from 1% to 25%, more preferably from 5% to 15%, most preferably from 5.5% to 8.0% by weight of the composition of a co-surfactant.

[0091] The auxiliary surfactant of the personal cleansing composition can include amphoteric surfactant or zwitterionic surfactant. Suitable amphoteric surfactant or zwitterionic surfactant can include those described in U.S. Patent No. 5,104,646 and U.S. Patent No. 5,106,609.

[0092] Amphoteric surfactants may include those broadly described as derivatives of aliphatic secondary and tertiary amines, wherein the aliphatic radical may be straight or branched chain, and wherein the aliphatic substituent may contain from 8 to 18 carbon atoms, such that one carbon atom may contain a water-solubilizing anionic group, such as a carboxyl, sulfonate, sulfate, phosphate, or phosphonate. Examples of compounds falling within this definition may be sodium 3-dodecyl-aminopropionate, sodium 3-dodecylaminopropane sulfonate, N-alkyltaurines (such as those prepared by reacting dodecylamine with sodium isethionate according to the teachings of U.S. Pat. No. 2,658,072), N-higher alkyl aspartic acids (such as those prepared according to the teachings of U.S. Pat. No. 2,438,091), and the products described in U.S. Pat. No. 2,528,378.

[0093] The amphoteric surfactants comprised in the personal cleansing compositions described herein may preferably be selected from the group consisting of sodium lauroamphoacetate, sodium cocoamphoacetate, disodium lauroamphoacetate, disodium cocoamphoacetate and mixtures thereof.

[0094] Zwitterionic surfactants suitable for use in the auxiliary surfactants of the personal cleansing compositions described herein can include those broadly described as derivatives of aliphatic quaternary ammonium, phosphonium and sulfonium compounds in which the aliphatic radical can be straight chain or branched and in which one of the aliphatic substituents can contain from 8 to 18 carbon atoms and one of the aliphatic substituents can contain an anionic group such as carboxy, sulfonate, sulfate, phosphate or phosphonate.

[0095] Preferably, the auxiliary surfactant may include a zwitterionic surfactant, wherein the zwitterionic surfactant includes an alkyl betaine or an alkylamidopropyl betaine.

[0096] Examples of betaine zwitterionic surfactants may include cocodimethyl carboxymethyl betaine, cocoamidopropyl betaine (CAPB), cocobetaine, lauroamidopropyl betaine (LAPB), oleyl betaine, lauryl dimethyl carboxymethyl betaine, lauryl dimethyl α-carboxyethyl betaine, cetyl dimethyl carboxymethyl betaine, lauryl di-(2-hydroxyethyl) carboxymethyl betaine, stearyl di-(2-hydroxypropyl) carboxymethyl betaine, oleyl dimethyl γ-carboxypropyl betaine, lauryl di-(2-hydroxypropyl) α-carboxyethyl betaine, and mixtures thereof. Examples of sulfobetaines may include cocodimethyl sulfopropyl betaine, stearyl dimethyl sulfopropyl betaine, lauryl dimethyl sulfoethyl betaine, lauryl di-(2-hydroxyethyl) sulfopropyl betaine, and mixtures thereof.

[0097] More preferably, the zwitterionic surfactant may be selected from the group consisting of cocamidopropyl betaine, lauroamidopropyl betaine, coco betaine and mixtures thereof.

[0098] The surfactant system may most preferably comprise 5.5% to 8.0% of a co-surfactant by weight of the composition, wherein the co-surfactant comprises a zwitterionic surfactant, wherein the zwitterionic surfactant is selected from the group consisting of cocamidopropyl betaine, lauroamidopropyl betaine, cocoyl betaine and mixtures thereof, preferably cocamidopropyl betaine. In this aspect, the phase stability of the personal cleansing composition may be further enhanced.

[0099] pH

[0100] The pH of the personal cleansing composition is preferably from 5.5 to 7, preferably from 5.5 to 6.5, more preferably from 5.6 to 6.1. Increasing the pH can help prevent hydrolysis of fatty acyl isethionates and fatty acyl sarcosinates. The pH can be measured according to the Product pH Measurement Test Method described below.

[0101] A variety of compounds can be used to adjust the pH of the composition. Such suitable compounds can include, but are not limited to, acetic acid, hydrochloric acid, sodium hydroxide, magnesium hydroxide, triethylamine, diethylamine, ethylamine, monoethanolamine, and any mixture thereof. The personal cleansing composition may contain greater than 0% to 2% of a pH adjuster by weight of the composition, preferably wherein the pH adjuster comprises citric acid.

[0102] Increasing the pH of the personal cleansing composition can help prevent phase separation of the personal cleansing composition.

[0103] Thickening system

[0104] The personal cleansing composition comprises from 0.05% to 5%, preferably from 0.1% to 2%, more preferably from 0.5% to 1.5%, most preferably from 0.75% to 1.0%, by weight of the composition, of a nonionic surfactant. Nonionic surfactants include fatty alkanolamides.

[0105] The fatty alkanolamide can be selected from the group consisting of cocamide, cocamide methyl MEA, cocamide MEA, cocamide DEA, cocamide MIPA, lauramide MEA, lauramide DEA, lauramide MIPA, myristic acid MEA, myristic acid DEA, PEG-20 cocamide MEA, PEG-2 cocamide, PEG-3 cocamide, PEG-4 cocamide, PEG-5 cocamide, PEG-6 cocamide, PEG-7 cocamide, PEG-3 lauramide, PEG-5 lauramide, PEG-3 oleamide, PPG-2 cocamide, PPG-2 hydroxyethyl cocamide, PPG-2 hydroxyethyl isostearamide, soyamide DEA, oleamide MIPA, stearamide MEA, myristic acid DEA, stearamide DEA, oleamide DEA, tallowamide DEA, lauramide MIPA, tallowamide MEA, isostearamide DEA, isostearamide MEA and mixtures thereof.

[0106] The fatty alkanolamide can be selected from the group consisting of cocamide, cocamide methyl MEA, cocamide MEA, cocamide DEA, cocamide MIPA, lauramide MEA, lauramide DEA, lauramide MIPA, myristicamide MEA, myristicamide DEA, soyamide DEA, oleamide MIPA, stearamide MEA, stearamide DEA, oleamide DEA, tallowamide DEA, lauramide MIPA, tallowamide MEA, isostearamide DEA, isostearamide MEA and mixtures thereof.

[0107] The fatty alkanolamide may preferably be selected from the group consisting of cocamide MEA, cocamide DEA, lauramide MEA, lauramide DEA, stearamide MEA, myristamide DEA, stearamide DEA and mixtures thereof.

[0108] Most preferably, the fatty alkanolamide may be cocamide MEA.

[0109] Fatty alkanolamides can help to significantly increase the lather creaminess of personal cleansing compositions.

[0110] Additionally, the personal cleansing composition comprises from 0.01% to 2%, preferably from 0.05% to 1.5%, more preferably from 0.07% to 0.50%, most preferably from 0.1% to 0.15%, by weight of the composition, of a hydrophobically modified ethoxylated methyl glucoside.

[0111] The hydrophobically modified ethoxylated methyl glucoside may be selected from the group consisting of PEG-120 methyl glucose dioleate, PEG-120 methyl glucose trioleate, PEG-20 methyl glucose sesquistearate, PEG-20 methyl glucose distearate, PEG-80 methyl glucose laurate, PEG-20 methyl glucose sesquistearate, PEG-120 methyl glucose triisostearate, and mixtures thereof.

[0112] Preferably, the hydrophobically modified ethoxylated methyl glucoside may be selected from the group consisting of PEG-120 methyl glucose dioleate, PEG-120 methyl glucose trioleate, PEG-20 methyl glucose sesquistearate, PEG-20 methyl glucose distearate and mixtures thereof.

[0113] More preferably, the hydrophobically modified ethoxylated methyl glucoside may be selected from the group consisting of PEG-120 methyl glucose dioleate, PEG-120 methyl glucose trioleate, and mixtures thereof. Most preferably, the hydrophobically modified ethoxylated methyl glucoside may comprise PEG-120 methyl glucose trioleate.

[0114] Hydrophobically modified ethoxylated methyl glucoside is a naturally derived thickener used to provide mildness in personal cleansing compositions.

[0115] Hydrophobically modified ethoxylated methyl glucosides are methyl glucose ethers that have been esterified with fatty acids such as oleic acid or stearic acid.

[0116] The hydrophobically modified ethoxylated methyl glucoside can also aid in conditioning, typically by reducing the amount of foam in personal cleansing compositions.

[0117] When a personal cleansing composition comprises a fatty alkanolamide and a hydrophobically modified ethoxylated methyl glucoside as described above, the phase stability of the personal cleansing composition is improved. The fatty alkanolamide and the hydrophobically modified ethoxylated methyl glucoside can effectively construct a personal cleansing composition with a desired and consistent viscosity. The fatty alkanolamide and the hydrophobically modified ethoxylated methyl glucoside can interact by extending from spherical micelles to worm-like micelles made of fatty acyl isethionate surfactants or fatty acyl isethionate surfactants and fatty acyl sarcosinates.

[0118] First, a preliminary evaluation of different thickeners was performed. Figure 1 Graph showing the effect of thickeners and their relative concentrations on enhancing the viscosity of a personal cleansing composition such as Comparative Example 1 as exemplified in the Examples section. The personal cleansing composition should have a target viscosity of about 4 Pa.s (4000 centipoise). At a 2 wt. % level, hydrophobically modified ethoxylated methyl glucosides such as PEG-120 methyl glucose dioleate or PEG-120 methyl glucose trioleate were found to significantly increase the viscosity of the personal cleansing composition compared to the same levels of other types of thickeners such as acrylate copolymers, PEG-200 hydrogenated palm glycerides with PEG-7 coconut glycerides, sorbitan caprylate with glyceryl oleate, or isostearamide MIPA with glyceryl laurate.

[0119] In addition, fatty alkanolamides such as cocamide MEA showed good response.

[0120] Figure 1 Other thickeners not shown in the results resulted in unacceptable precipitated gels. Unsuitable thickeners were PEG-14M, PEG-2M, PQ-10, hydroxypropylmethylcellulose or sodium carboxymethylcellulose.

[0121] Cationic polymers such as polyquaternium-10 are too hydrophilic and provide relatively weak interactions with the surfactant system.

[0122] Anionic polymers (ie, acrylate copolymers) also provide too weak an interaction with the surfactant of the composition due to too high an ionic strength.

[0123] Hydrophobically modified ethoxylated methyl glucoside is believed to effectively interact with surfactant micelles due to its relatively high number of hydrophobic blocks and compatibility with the surfactant system.

[0124] Figure 2 Graph showing the effect of a thickening system at various levels of electrolyte (sodium chloride) on enhancing the viscosity of a personal cleansing composition (such as exemplified by Comparative Example 1 as detailed in the Examples section).

[0125] For different levels of sodium chloride of 0%, 1% and 2% by weight of the composition, it has been found that a combination of 2% by weight cocamide MEA and 1% by weight PEG-20 methyl glucose trioleate provides adequate viscosity.

[0126] In particular, the same results were obtained for the combination of 1 wt% cocamide MEA and 0.12 wt% PEG-20 methyl glucose trioleate. The weight ratio of fatty alkanolamide to hydrophobically modified ethoxylated methyl glucoside was then 8.3.

[0127] The viscosity target was achieved by adding 2 wt% sodium chloride. For 1 wt% sodium chloride, the viscosity was between 2000 and 4000 centipoise, which is acceptable.

[0128] Interestingly, these results were also observed in the Examples section below without the addition of any electrolytes such as sodium chloride. Thus, any addition of electrolytes is merely an option to further adjust the viscosity of the personal cleansing composition if necessary.

[0129] Additionally, the levels of both the fatty alkanolamide and the hydrophobically modified ethoxylated methyl glucoside may be reduced in a certain weight ratio to provide the desired viscosity of the composition.

[0130] Thus, the weight ratio of fatty alkanolamide to hydrophobically modified ethoxylated methyl glucoside may range from 2 to 12, preferably from 5 to 10, more preferably from 8 to 9.

[0131] Alternatively, the fatty alkanolamide may comprise cocamide MEA, and the hydrophobically modified ethoxylated methyl glucoside may be selected from the group consisting of PEG-120 methyl glucose dioleate, PEG-120 methyl glucose trioleate and mixtures thereof, wherein the weight ratio of the fatty alkanolamide to the hydrophobically modified ethoxylated methyl glucoside ranges from 5 to 12, preferably from 7 to 10, more preferably from 8 to 9.

[0132] Preferably, the fatty alkanolamide may comprise cocamide MEA and the hydrophobically modified ethoxylated methyl glucoside may comprise PEG-120 methyl glucose trioleate, wherein the weight ratio of the fatty alkanolamide to the hydrophobically modified ethoxylated methyl glucoside ranges from 5 to 12, preferably from 7 to 10, more preferably from 8 to 9.

[0133] preservative

[0134] Increasing the pH may have an adverse effect on the preservative system. Salicylic acid between pH 5.5 and 7 may be deprotonated and may not act as a robust preservative.

[0135] Additionally, the addition of fatty alkanolamides (eg, cocamide MEA) and hydrophobically modified ethoxylated methyl glucoside as described above may result in discoloration of the personal cleansing composition.

[0136] Thus, the personal cleansing compositions comprise from 0.01% to 1.0%, preferably from 0.02% to 0.4%, more preferably from 0.05% to 0.2%, most preferably from 0.05% to 0.1% preservative by weight of the composition.

[0137] The preservative may be selected from the group consisting of alkali metal metabisulfites, alkali metal sulfites, alkali metal bisulfites, alkali metal dithionites and mixtures thereof. The alkali metal may be lithium, sodium or potassium.

[0138] The preservative may be selected from the group consisting of sodium metabisulfite, sodium sulfite, sodium dithionite, potassium sulfite, sodium bisulfite, potassium bisulfite and mixtures thereof. Preferably, the preservative may include sodium bisulfite.

[0139] The personal cleansing composition may comprise from 0.05% to 0.2%, preferably from 0.05% to 0.1%, of a preservative by weight of the composition, wherein the preservative is selected from the group consisting of sodium metabisulfite, sodium sulfite, sodium dithionite, potassium sulfite, sodium bisulfite, potassium bisulfite and mixtures thereof, more preferably wherein the preservative comprises sodium bisulfite.

[0140] Preservatives may also include salicylates and benzoates, wherein the total amount of salicylates and benzoates is from 0.2% to 0.9%, preferably from 0.5% to 0.85%, more preferably from 0.75% to 0.85% by weight of the composition.

[0141] The weight ratio of salicylate to benzoate may be 1:1.20 to 1:1.10, preferably 1:1.175 to 1:1.125.

[0142] The personal cleansing composition may comprise from 0.05% to 0.2%, preferably from 0.05% to 0.1%, of a preservative by weight of the composition, wherein the preservative is selected from the group consisting of sodium metabisulfite, sodium sulfite, sodium dithionite, potassium sulfite, sodium bisulfite, potassium bisulfite and mixtures thereof, more preferably wherein the preservative comprises sodium bisulfite; and additionally salicylates and benzoates, wherein the total amount of salicylates and benzoates is from 0.2% to 0.9%, preferably from 0.5% to 0.85%, more preferably from 0.75% to 0.85%, by weight of the composition.

[0143] The salicylate may be sodium salicylate. The benzoate may be sodium benzoate.

[0144] Preservatives as described herein may also prevent any discoloration of personal cleansing compositions containing betaine or fragrance components. In fact, some fragrance components may contain aldehydes and amines that may react together and may provide discoloration over time.

[0145] In addition, the preservative may exhibit relatively strong antimicrobial efficacy at the pH range of 5.5 to 7, especially at pH 6.4.

[0146] Preservatives may also contribute to some extent to the antimicrobial preservation of the personal cleansing composition.

[0147] Electrolytes

[0148] The personal cleansing composition may further comprise from 0.05% to 5%, preferably from 0.5% to 4%, more preferably from 1.0% to 2% electrolyte by weight of the composition. The addition of electrolytes may help to extend the micelles of the surfactant system and further improve the viscosity of the composition if desired.

[0149] The electrolyte may be selected from the group consisting of sodium or potassium citrate, calcium chloride, calcium bromide, zinc chloride, barium chloride, calcium nitrate, potassium chloride, sodium chloride, potassium iodide, sodium bromide, ammonium bromide, sodium sulfate, and mixtures thereof.

[0150] The electrolyte may preferably be selected from the group comprising sodium citrate or potassium citrate, calcium chloride, potassium chloride, sodium chloride, and mixtures thereof.

[0151] Most preferably, the personal cleansing composition may further comprise from 1.0% to 2%, by weight of the composition, of an electrolyte, wherein the electrolyte is sodium chloride.

[0152] Optional Ingredients

[0153] As can be appreciated, the cleaning compositions described herein can include a variety of optional components to adjust the properties and characteristics of the composition. As can be appreciated, suitable optional components are well known and can generally include any component that is physically and chemically compatible with the essential components of the composition described herein. The optional components should not otherwise unduly impair the stability, aesthetics or performance of the product. The independent concentration of the optional components can generally be in the range of 0.001% to 10% by weight of the composition. The optional components can be further limited to components that will not impair the transparency of the translucent composition.

[0154] Additionally, the personal cleansing composition may not include or may be free of direct dyes, oxidative dyes, parabens, or mixtures thereof.

[0155] Optional components may include, but are not limited to, conditioning agents (including hydrocarbon oils, fatty acid esters, silicones), cationic polymers, anti-dandruff actives and chelating agents. Additional suitable optional ingredients include, but are not limited to, particles, antimicrobial agents, foam boosters, antistatic agents, humectants, propellants, self-foaming agents, pearlescent agents, opacifiers, sensates, suspending agents, solvents, diluents, antioxidants, vitamins and mixtures thereof.

[0156] Fragrance ingredients

[0157] The personal cleansing composition may comprise from 0.01 wt% to 2 wt% of the fragrance component by weight of the composition, preferably from 0.1 wt% to 1.75 wt% of the fragrance component by weight of the composition, more preferably from 0.5 wt% to 1.6 wt% of the fragrance component by weight of the composition, even more preferably from 0.8 wt% to 1.0 wt% of the fragrance component by weight of the composition.

[0158] Typically, fragrance components can be a blend of perfumes and aroma chemicals.As used herein, "fragrance" is used to refer to any odor-emitting material.

[0159] A variety of chemicals are known as fragrances, including alcohols, aldehydes, ketones and esters. Non-limiting examples of fragrances that can be used herein include fragrance precursors, such as acetal fragrance precursors, ketal fragrance precursors, ester fragrance precursors, hydrolyzable inorganic-organic fragrance precursors and mixtures thereof. Fragrances can be released from fragrance precursors in a variety of ways. For example, fragrances can be released as a result of simple hydrolysis, or by moving in an equilibrium reaction, or by pH-changes, or by enzyme release. Fragrances herein can be relatively simple in their chemical composition, comprising a single chemical, or can comprise a highly complex composite mixture of natural and synthetic chemical components, all of which are selected to provide any desired odor.

[0160] The fragrance may have a boiling point (BP) of 500° C. or less, 400° C. or less, or 350° C. or less. The BP of many fragrances is disclosed in Perfume and Flavor Chemicals, Steffen Arctander (1969). The ClogP value of the fragrance may be 0.1 or greater, 0.5 or greater, 1.0 or greater, and 1.2 or greater. As used herein, "ClogP" refers to the logarithm of the octanol / water partition coefficient to the base 10. ClogP can be easily calculated by a program called "CLOGP", which can be obtained from Daylight Chemical Information Systems Inc., Irvine Calif., USA. The octanol / water partition coefficient is described in more detail in U.S. Patent No. 5,578,563.

[0161] Suitable fragrances are also disclosed in U.S. Pat. No. 4,145,184, U.S. Pat. No. 4,209,417, U.S. Pat. No. 4,515,705, and U.S. Pat. No. 4,152,272. Non-limiting examples of fragrances include animal fragrances such as musk oil, civet, castoreum, ambergris, plant fragrances such as nutmeg extract, cardamom extract, ginger extract, cinnamon extract, patchouli oil, geranium oil, orange oil, tangerine oil, orange Hower extract, cedar, vetiver, lavender, ylang-ylang extract, tuberose extract, sandalwood oil, bergamot oil, rosemary oil, spearmint oil, peppermint oil, lemon oil, lavender oil, citronella oil, chamomile oil, clove oil, sage oil, neroli oil, labdanum oil, eucalyptus oil, verbena oil, mimosa extract, narcissus extract, carrot seed extract, jasmine extract, frankincense extract, rose extract, and mixtures thereof.

[0162] Other examples of suitable fragrances include, but are not limited to, chemicals such as acetophenone, adoxaldehyde, aldehyde C-12, aldehyde C-14, aldehyde C-18, allyl octanoate, ambroxan, amyl acetate, dimethyl indane derivatives, alpha-amyl cinnamaldehyde, anethole, anisaldehyde, benzaldehyde, borneol, butyl acetate, camphor, carbitol, cinnamaldehyde, cinnamyl acetate, cinnamyl alcohol, cis-3-hexanol and ester derivatives, cis-3-hexenol methyl carbonate, citral, citronellol and ester derivatives, cuminaldehyde, cyclamen aldehyde, cyclopentyl, damascenone, decalactone, decanol, estragole, dihydromyrcenol, dimethylbenzyl alcohol, 6,8-dimethyl-2-nonanol, dimethylbenzyl butyrate, ethyl acetate, ethyl isobutyrate, ethyl butyrate, ethyl propionate, ethyl octanoate, ethyl cinnamate, ethyl caproate, ethyl valerate, ethyl vanillin, eugenol, cyclopentadecalactone, fenchone, fruity esters such as ethyl 2-methylbutyrate, galaxol, geraniol and ester derivatives, neoheterol, 2-heptanone, hexenol, α-hexylcinnamaldehyde, hydroxycitronellal, indole, isoamyl acetate, isoeugenyl acetate, ionone, isoeugenol, isoamyl isovalerate, Iso E Super, limonene, linalool, lilyal, linalool acetate, lyral, maltol, mayol, melonal, menthol, p-methylacetophenone, methyl anthranilate, methyl cedryl ketone, methyl dihydrojasmonate, methyl eugenol, methyl ionone, methyl-α-naphthyl ketone, methyl phenyl acetate, mugetanol, γ-nonalactone, octanal, phenylethyl acetate, phenylacetaldehyde dimethyl acetate, phenoxyethyl isobutyrate, phenylethyl alcohol, pinene, sandalwood, santaiol, oleagin, thymol, terpenes, privet aldehyde, triethyl citrate, 3,3,5-trimethylcyclohexanol, γ-undecalactone, undecenal, vanillin, vanalone, verdox and mixtures thereof.

[0163] In the personal cleansing composition, the fragrance component may include ketone and / or aldehyde fragrance components. In addition, the fragrance component may also include any fragrance described above.

[0164] The ketone fragrance component may be selected from alicyclic ketones (such as β-ionone), terpene ketones (such as 1-carvone) and macrocyclic ketones (such as cyclopentadecanone).

[0165] The aldehyde fragrance component may be selected from aliphatic aldehydes (such as 2,6-nonadienal), terpene aldehydes (such as citral) and aromatic aldehydes (such as α-hexylcinnamaldehyde, cinnamaldehyde).

[0166] Therefore, preferably, the fragrance component may include a ketone and / or aldehyde fragrance component, wherein the ketone and / or aldehyde fragrance component may be selected from the group consisting of acetophenone, adoc aldehyde, aldehyde C-12, aldehyde C-14, aldehyde C-18, α-amyl cinnamaldehyde, anise aldehyde, benzaldehyde, camphor, cinnamaldehyde, citral, cuminaldehyde, cyclamen aldehyde, damascenone, fenchone, heliotropin, 2-heptanone, α-hexyl cinnamaldehyde, hydroxycitronellal, ionone, lilyral, lilyral, melonal, p-methylacetophenone, methyl cedryl ketone, methyl ionone, methyl-α-naphthyl ketone, γ-nonalactone, octanal, phenylacetaldehyde dimethyl acetate, privet aldehyde, γ-undecalactone, undecenal, vanillin, vanillone and mixtures thereof.

[0167] method

[0168] A method of increasing the stability of a personal cleansing composition with respect to phase, color and microbial stability is provided and comprises the steps of forming a personal cleansing composition as described herein.

[0169] Form and use

[0170] Product form

[0171] The personal cleansing composition may be presented as a typical personal cleansing formulation. The shampoo composition may be in the form of a solution, dispersion, emulsion, foam and other delivery mechanisms. The personal cleansing composition may be a rinse-off composition.

[0172] The personal cleansing composition can be squeezed out or dispensed from a single chamber package.The personal cleansing composition may be in the form of a liquid, semi-liquid, cream, lotion or gel or a solid composition intended for topical application to the skin.

[0173] Examples of personal cleansing compositions may include, but are not limited to, body washes, moisturizing body washes, foaming body washes, shower gels, bath or shower creams, skin cleansers, cleansing milks, body washes, bath moisturizers, gels, lotions, oils, mousses, or sprays.

[0174] The personal cleansing composition may not be in the form of a liquid hand wash or a liquid hand sanitizer.

[0175] The product form contemplated for purposes of defining personal cleansing compositions and methods is a rinse-off formulation, meaning that the product is applied topically to the skin and then subsequently (ie, within a few minutes) washed off with water or otherwise wiped off using a substrate or other suitable removal device.

[0176] use

[0177] The personal cleansing compositions as described above may be used to improve the lather of the composition.

[0178] The personal cleansing composition as described above can be used to suspend a benefit agent selected from hair care and skin care benefit agents, microparticles, preferably particles of silica and titanium oxide, microcapsules, oils, droplets, pigments or colorants, opacifiers, pearlescent agents, feel modifiers, oil absorbers, skin protectants, matting agents, friction enhancers, slip agents, conditioning agents, exfoliants, odor absorbers, or cleaning enhancers, and mixtures thereof.

[0179] The personal cleansing compositions can advantageously provide relatively improved ecotoxicity or eco-friendly environmental characteristics.

[0180] The personal cleansing composition can help provide good aesthetic properties such as good lather, and be thick and creamy in texture, silky to the touch, and provide a conditioning benefit.

[0181] Test Method

[0182] It should be understood that the test methods disclosed in the Test Methods section of this application should be used to determine the corresponding parameter values ​​of this invention as described and protected by applicant's invention.

[0183] Cone / Plate Viscosity Measurement

[0184] The viscosity of the personal cleansing composition was measured by a cone / plate Brookfield DV12T from Brookfield Engineering Laboratories (Stoughton, MA). The cone (spindle CPA-41z) used had a diameter of 24 mm and an angle of 3°. The viscosity was measured using a steady-state flow test at a temperature of 26.5° C. for 2 s -1 The sample volume was 2.5 mL.

[0185] Microbial resistance measurement

[0186] Test microorganisms

[0187] Cultures of the following microorganisms are used: Candida albicans, Aspergillus niger, Escherichia coli, Pseudomonas aeruginosa, Burkholderia cepacian, Klebsiella pneumoniae, Enterobacter gergoviae, Serratia marcescens, and Staphylococcus aureus. The live microorganisms used in the test must not exceed five passages removed from the original culture. For the purpose of the test, one passage is defined as the transfer of a microorganism from an established culture to a fresh medium. All transfers are counted. With respect to maintaining microorganisms by seed batch technology, each cycle of freezing, thawing, and recovery in a fresh medium is considered a transfer. Seed stock technology should be used for long-term storage of cultures.

[0188] Table 1. Test microorganisms

[0189]

[0190] Preparation of inoculum

[0191] Prior to testing, a recently recovered stock culture of each of the designated microorganisms is inoculated onto the surface of a suitable volume of solid agar medium.

[0192] To harvest bacterial and C. albicans cultures, sterile saline solution was used to obtain between 1×10 5 and 1×10 7 To harvest the cells of A. brasiliensis, a sterile saline solution containing 0.05% polysorbate 80 was used, and enough sterile saline solution was added to obtain a count of 1×10 7 Up to 1×10 8 cfu / mL.

[0193] To form a pooled inoculum, aliquots of each of the bacteria or yeast and molds desired for the library described in Table 1 were mixed.

[0194] program

[0195] The test can be carried out in two sterile, capped bacteriological containers of suitable size into which a sufficient volume of product has been transferred. Each container is inoculated with v of the prepared standardized inoculum and mixed. The volume of the suspended inoculum used is 1.0% of the volume of the product. The concentration of the test microorganism added to the product is such that the final concentration of the test preparation after inoculation is between 1×10 5 and 1×10 7 cfu / mL between products.

[0196] The initial concentration of viable microorganisms in each test formulation was estimated based on the concentration of microorganisms in each inoculum in the standardized inoculum as determined by the plate count method.

[0197] Incubate the inoculated containers at 20°C to 25°C. Record any changes in appearance observed at these intervals. Determine the number of cfu present in each test formulation at the applicable interval by a plate count procedure. Inactivators (neutralizers) for specific antimicrobial agents are incorporated into the plate count or appropriate dilutions are prepared for plating. Using the calculated concentration (cfu / mL) present at the start of the test, calculate the change in the log10 value of the concentration (cfu / mL) of each microorganism at the applicable test interval, and express the change in terms of logarithmic reduction.

[0198] Product pH Measurement

[0199] First, calibrate the Metler TOLEDO pH meter. This is done by starting the pH meter and waiting 30 seconds. Then, remove the electrode from the storage solution, rinse the electrode with reverse osmosis (RO) water, and clean it with a scientific cleaning wipe such as Carefully wipe the electrode. Immerse the electrode in pH 4 buffer and press the calibration button. Wait until the pH icon stops flashing. Rinse the electrode with RO water and wipe the electrode carefully with a scientific cleaning wipe. Then, immerse the electrode in pH 7 buffer and wait until the pH icon stops flashing. Rinse the electrode with RO water and wipe it carefully with a scientific cleaning wipe. Then, immerse the electrode in pH 9 buffer and wait until the pH icon stops flashing. Rinse the electrode with distilled RO water and wipe it carefully with a scientific cleaning wipe. The pH meter is now calibrated and can be used to test the pH of a solution.

[0200] Color Change Test Method

[0201] The color change test method is used to monitor color stability and assess whether discoloration has been prevented or reduced. In the color change test method, the composition to be evaluated is punched into a size of (62mm*37mm*16.5mm). The color of the composition to be tested is evaluated via transmission mode using a desktop spectrophotometer (X-rite Ci 7800 instrument). The composition to be tested is placed between two orifice plates in the measurement chamber. The incident light is transmitted through the composition to be tested, and the absorbance of the light is recorded within the wavelength range of 360nm to 780nm. The resulting curve is converted into various color scales L*, a* and b* values.

[0202] L* represents the lightness of the color, a* represents the green / red axis, and b* represents the blue / yellow axis.

[0203] Color analysis is based on individual color components in the Hunter L*a*b* color space, where:

[0204] L* = lightness (L* = 0 gives black, and L* = 100 indicates diffuse white)

[0205] a* = red / green (a*, negative values ​​represent green, while positive values ​​represent red)

[0206] b*=yellow to blue (b*, negative values ​​represent blue, and positive values ​​represent yellow)

[0207] To evaluate the color stability of the compositions, the color of the compositions was measured when they were freshly prepared and after aging at 75°C for 4 hours.

[0208] Given ΔL*Δa*Δb*, the total difference or distance on the Hunter L*a*b* scale can be expressed as a single value, called ΔE*.

[0209] ΔE*=((L*1-L*2) 2 +(a*1-a*2) 2 +(b*1-b*2) 2 ) 1 / 2 .

[0210] in

[0211] L*1, a*1, b*1 are the values ​​for a freshly prepared composition ("initial"); L*2, a*2, b*2 are the values ​​for an aged composition ("final").

[0212] Higher ΔE* values ​​indicate a greater color shift from the initial value, which is undesirable, meaning that more color has been formed within the personal cleansing composition.

[0213] Example

[0214] The following examples further describe and demonstrate embodiments within the scope of the present invention. These examples are provided for illustrative purposes only and should not be construed as limitations of the present invention, as there may be many variations without departing from the spirit and scope of the present invention. Applicable ingredients herein are identified by chemical name or CTFA name, unless otherwise defined below.

[0215] The following examples were prepared:

[0216] Composition (wt%)

[0217]

[0218]

[0219] Component Definition

[0220] *1Sodium cocoyl isethionate; Supplier: Clariant

[0221] *2 Sodium lauroyl sarcosinate; Supplier: Tinci

[0222] *4 Cocamidopropyl betaine; Supplier: Tinci

[0223] *5Glucamate TM LT; Supplier Lubrizol Advanced Materials

[0224] *6 Sodium salicylate; Supplier: JQC Huayn Pharmaeutical Co Ltd.

[0225] *7 Sodium benzoate; Supplier: Wuhan Youji Industries

[0226] *8Citric acid powder; supplier: Yixing Union Biochemical

[0227] *9 Sodium bisulfite: Supplier: Suzhou Boyang Chemical Co., Ltd.

[0228] qs: sufficient

[0229] result :

[0230] Phase stability and enhanced viscosity

[0231] The personal cleansing composition should have an initial viscosity of about 4 Pa.s (4000 centipoise) and should have a viscosity of less than 15 Pa.s (15000 centipoise) but not less than 3 Pa.s (3000 centipoise) after storage at 60°C for 3 weeks.

[0232] Comparative Example 1 is a personal cleansing composition comprising sodium cocoyl isethionate, sodium lauroyl sarcosinate and cocamidopropyl betaine at pH 5.0. After storage at 60°C for 3 weeks, phase separation was observed and the initial viscosity decreased.

[0233] The top floating layer is the lamellar phase layer, which is relatively highly ordered and contains the above surfactants with relatively less water. Due to their lower density, the lamellar phase floats and is the upper layer. The micellar phase is the lower layer.

[0234] Free fatty acids derived from sodium cocoyl isethionate or sodium lauroyl sarcosinate (due to the corresponding hydrolysis of the anionic surfactants) can contribute to the phase transition and phase separation from the micellar phase to the lamellar phase.

[0235] Initially, the hydrolysis of sodium cocoyl isethionate or sodium lauroyl sarcosinate results in an increase in viscosity due to the elongation of worm-like micelles. However, after a certain amount of free fatty acids are generated, the worm-like and spherical micelles transform from worm-like micelles into larger, more complex aggregates (such as discoid micelles or gel networks). At this point, these structures reduce the number of entanglements, reduce flow resistance, and increase the fluidity of the system, resulting in a decrease in viscosity. The lamellar phase separates from the micellar phase.

[0236] When the pH increases from 5.0 to 6.1 (in Comparative Example 2), the hydrolysis kinetics of sodium cocoyl isethionate and sodium lauroyl sarcosinate have slowed down. No phase separation is observed. However, the rheology of the personal cleansing composition is still not satisfactory to the consumer.

[0237] In Comparative Example 3, 1 wt% of cocamide MEA has been added which improves the viscosity properties of the personal cleansing composition.

[0238] Examples 1 and 2 show that the combination of cocamide MEA as the fatty alkanolamide and PEG-120 methyl glucose trioleate as the hydrophobically modified ethoxylated methyl glucoside can build the texture of the composition at the desired enhanced viscosity. It has been found that the elongation from spherical micelles to worm-like micelles can be demonstrated by Cryo-TEM and NMR.

[0239] When PEG-120 methyl glucose trioleate is replaced by Lubrizol as Glucamate in Example 1 or Example 2, TM Similar results were obtained when using PEG-120 methyl glucose dioleate supplied by DOE-120. The aim was to achieve an initial viscosity target of approximately 4 Pa.s.

[0240] like Figure 1Initially, it was shown that when the hydrophobically modified ethoxylated methyl glucoside (such as that produced by Lubrizol as Glucamate TM LT) without any fatty alkanolamide, was also found to enhance the composition texture better than the following at the desired enhanced viscosity:

[0241] -PEG-200 Hydrogenated Palm Glycerides / PEG-7 Cocoyl Glycerides, by Evonik as

[0242] 200MB supply;

[0243] -Acrylate copolymers, manufactured by Lubrizol as Aqua SF-2 supplies;

[0244] - Sorbitan caprylate / glyceryl oleate, by Evonik as REMO

[0245] 95MB supply; or

[0246] - Isostearamide MIPA / glyceryl laurate, supplied as SPA 80 by Evonik.

[0247] In particular, cellulosic type polymers such as hydroxypropyl methylcellulose or sodium carboxymethylcellulose fail to build the desired viscosity and precipitation may be observed.

[0248] Even at different electrolyte levels, hydroxypropyl methylcellulose was not an interesting thickener, e.g. Figure 2 shown.

[0249] When a mixture of a fatty alkanolamide (such as cocamide MEA) and a hydrophobically modified ethoxylated methyl glucoside (such as PEG-120 methyl glucose trioleate) is used, the desired viscosity of the personal cleansing composition can be achieved at a weight ratio of fatty alkanolamide to hydrophobically modified ethoxylated methyl glucoside of 2 or 8.3 (see Figure 2 ).

[0250] Thus, it has been found that the weight ratio of fatty alkanolamide to hydrophobically modified ethoxylated methyl glucoside ranges from 2 to 12, preferably from 5 to 10, more preferably from 8 to 9 (especially in Example 1 where the weight ratio is 8.3).

[0251] Antimicrobial and bleaching stability

[0252] In terms of color stability, a personal cleansing composition should have a ΔE* as small as possible after storage at 60°C for 3 weeks.

[0253] Example 1 has a similar ΔE* to Comparative Example 2. Example 1 is an acceptable personal cleansing composition.

[0254] In addition, it is necessary to further prevent discoloration after storage at 60°C for 3 weeks.

[0255] When sodium bisulfite was added in Example 2 versus Example 1, the reduction in ΔE* obtained indicated that discoloration had been prevented.

[0256] As a dual function, sodium bisulfite as a preservative is not only effective in preventing discoloration of personal cleansing compositions, but also exhibits strong antimicrobial efficacy at the claimed pH.

[0257] Comparative Example 2 has an increased pH compared to Comparative Example 1, the protonated salicylic acid is not strong enough to provide any antimicrobial preservative effect.

[0258] When comparing Comparative Example 4 to Comparative Example 3, a single addition of sodium bisulfite can help to significantly increase the antimicrobial preservation effect.

[0259] When comparing Example 2 to Example 1, a single addition of sodium bisulfite can help to significantly increase the antimicrobial preservation effect.

[0260] Thus, preservatives such as alkali metal metabisulfite, alkali metal sulfite, alkali metal bisulfite (e.g. sodium bisulfite), alkali metal dithionite or mixtures thereof can prevent any discoloration at said pH 5.5 to 7 and enhance the antimicrobial preservative effect of the personal cleansing composition.

[0261] The following examples illustrate various aspects of the invention:

[0262] Composition (wt%)

[0263]

[0264]

[0265]

[0266] Component Definition

[0267] *10 Sodium chloride; supplier: Morton International

[0268] *11Glucamate TM DOE-120; Supplier Lubrizol Advanced Materials

[0269] The dimensions and values ​​disclosed herein should not be understood as being strictly limited to the exact numerical values ​​cited. Instead, unless otherwise indicated, each such dimension is intended to represent the stated value and a functionally equivalent range around that value. For example, a dimension disclosed as "40 mm" is intended to mean "about 40 mm".

[0270] Unless expressly excluded or otherwise limited, each document cited herein, including any cross-referenced or related patent or application, is incorporated herein by reference in its entirety. Citation of any document is not an admission that it is prior art to any of the present invention disclosed or claimed herein, or that it, by itself or in combination with any one or more references, proposes, suggests, or discloses any such invention. In addition, to the extent that any meaning or definition of a term in this invention conflicts with any meaning or definition of the same term in a document incorporated by reference, the meaning or definition assigned to that term in this invention shall govern.

[0271] Although specific embodiments of the present invention have been illustrated and described, it will be apparent to those skilled in the art that various other changes and modifications may be made without departing from the spirit and scope of the present invention. Therefore, it is intended that all such changes and modifications within the scope of the present invention be covered in the appended claims.

Claims

1. A personal cleaning composition, comprising: a) a surfactant system, wherein the surfactant system comprises: (i) from 0.1% to 5%, preferably from 0.5% to 4%, more preferably from 1% to 3%, most preferably from 1.5% to 2.5% by weight of the composition of a fatty acyl isethionate surfactant; (ii) from 0.5% to 40%, preferably from 1% to 25%, more preferably from 5% to 15%, most preferably from 5.5% to 8.0% by weight of the composition of a co-surfactant; wherein the composition does not contain surfactants of the alkyl sulfate or alkyl ether sulfate type; b) from 0.05% to 5%, preferably from 0.1% to 2%, more preferably from 0.5% to 1.5%, most preferably from 0.75% to 1.0% by weight of the composition of a nonionic surfactant, wherein the nonionic surfactant comprises a fatty alkanolamide; c) from 0.01% to 2.0%, preferably from 0.05% to 1.5%, more preferably from 0.07% to 0.5%, most preferably from 0.1% to 0.15%, by weight of the composition, of a hydrophobically modified ethoxylated methyl glucoside; d) from 0.01% to 1.0%, preferably from 0.02% to 0.4%, more preferably from 0.05% to 0.2%, most preferably from 0.05% to 0.1% by weight of the composition of a preservative; and e) wherein the pH is from 5.5 to 7, preferably from 5.5 to 6.5, more preferably from 5.6 to 6.

1.

2. The personal cleansing composition according to claim 1, wherein the fatty acyl isethionate surfactant is an isethionate according to formula (I): wherein R1 is a saturated or unsaturated linear or branched alkyl or alkenyl chain having 6 to 30 carbon atoms, preferably 8 to 22 carbon atoms, more preferably 9 to 18 carbon atoms, R2 and R3 are each independently H or (C1-C4) alkyl, and M + is an alkali metal, preferably lithium, sodium, potassium; or M + is an alkaline earth metal, preferably magnesium; or M + is an ammonium or substituted ammonium cation.

3. The personal cleansing composition of any one of the preceding claims, wherein the fatty acyl isethionate surfactant is selected from the group consisting of sodium lauroyl isethionate, sodium lauroyl methyl isethionate, sodium oleoyl isethionate, sodium oleoyl methyl isethionate, sodium stearoyl isethionate, sodium stearoyl methyl isethionate, sodium myristoyl isethionate, sodium myristoyl methyl isethionate, sodium palmitoyl isethionate, sodium palmitoyl methyl isethionate, sodium cocoyl isethionate, sodium cocoyl methyl isethionate, a blend of stearic acid and sodium cocoyl isethionate, ammonium cocoyl methyl isethionate, ammonium cocoyl methyl isethionate and mixtures thereof, preferably wherein the fatty acyl isethionate surfactant is selected from the group consisting of sodium lauroyl isethionate, sodium cocoyl isethionate, ammonium cocoyl methyl isethionate and mixtures thereof.

4. A personal cleansing composition according to any one of the preceding claims, wherein the surfactant system further comprises: (iii) from 0.1% to 10%, preferably from 0.5% to 8%, more preferably from 1% to 5%, most preferably from 3.5% to 5%, by weight of the composition, of a fatty acyl sarcosinate surfactant according to general formula (II): wherein R is a saturated or unsaturated linear or branched alkyl or alkenyl chain having 7 to 17 carbon atoms, preferably 9 to 13 carbon atoms, preferably an alkyl chain, and M + It is H, sodium cation, potassium cation or ammonium cation.

5. The personal cleansing composition according to claim 4, wherein the fatty acyl sarcosinate surfactant is selected from the group consisting of sodium lauroyl sarcosinate, sodium cocoyl sarcosinate, sodium myristoyl sarcosinate, TEA-cocoyl sarcosinate, ammonium cocoyl sarcosinate, ammonium lauroyl sarcosinate, dimer dilinoleyl dilauroyl glutamate / lauroyl sarcosinate, lauroyl sarcosinate, isopropyl lauroyl sarcosinate, potassium cocoyl sarcosinate, potassium lauroyl sarcosinate, sodium oleoyl sarcosinate, sodium palmitoyl sarcosinate, TEA-lauroyl sarcosinate, TEA-oleoyl sarcosinate, TEA-palm kernel sarcosinate and mixtures thereof, preferably wherein the fatty acyl sarcosinate surfactant is selected from the group consisting of sodium lauroyl sarcosinate, sodium myristoyl sarcosinate, sodium cocoyl sarcosinate and mixtures thereof.

6. A personal cleansing composition according to any one of the preceding claims, wherein the personal cleansing composition further comprises from 0.05% to 5%, preferably from 0.5% to 4%, more preferably from 1.0% to 2% of an electrolyte by weight of the composition, wherein the electrolyte is selected from the group consisting of sodium or potassium citrate, calcium chloride, calcium bromide, zinc chloride, barium chloride, calcium nitrate, potassium chloride, sodium chloride, potassium iodide, sodium bromide, ammonium bromide, sodium sulfate and mixtures thereof, preferably wherein the electrolyte is selected from the group consisting of sodium or potassium citrate, calcium chloride, potassium chloride, sodium chloride and mixtures thereof, most preferably wherein the personal cleansing composition further comprises from 1.0% to 2% of an electrolyte by weight of the composition, wherein the electrolyte is sodium chloride.

7. A personal cleansing composition according to any one of the preceding claims, wherein the personal cleansing composition further comprises 0.01 wt% to 2 wt% of a fragrance component by weight of the composition, preferably 0.1 wt% to 1.75 wt% of a fragrance component by weight of the composition, more preferably 0.5 wt% to 1.6 wt% of a fragrance component by weight of the composition, even more preferably 0.8 wt% to 1.0 wt% of a fragrance component by weight of the composition.

8. A personal cleansing composition according to any of the preceding claims, wherein the fatty alkanolamide is selected from the group consisting of cocamide, cocamide methyl MEA, cocamide MEA, cocamide DEA, cocamide MIPA, lauramide MEA, lauramide DEA, lauramide MIPA, myristic acid amide MEA, myristic acid amide DEA, PEG-20 cocamide MEA, PEG-2 cocamide, PEG-3 cocamide, PEG-4 cocamide, PEG-5 cocamide, PEG-6 cocamide, PEG-7 cocamide, PEG-8 cocamide, PEG-9 cocamide, PEG-10 cocamide, PEG-11 cocamide, PEG-12 cocamide, PEG-13 cocamide, PEG-14 cocamide, PEG-15 cocamide, PEG-16 cocamide, PEG-17 cocamide, PEG-18 cocamide, PEG-19 cocamide, EG-6 cocamide, PEG-7 cocamide, PEG-3 lauramide, PEG-5 lauramide, PEG-3 oleamide, PPG-2 cocamide, PPG-2 hydroxyethyl cocamide, PPG-2 hydroxyethyl isostearamide, soyamide DEA, oleamide MIPA, stearamide MEA, myristicamide DEA, stearamide DEA, oleamide DEA, tallowamide DEA, lauramide MIPA, tallowamide MEA, isostearamide DEA, isostearamide MEA and mixtures thereof.

9. A personal cleansing composition according to any one of the preceding claims wherein the fatty alkanolamide is selected from the group consisting of cocamide, cocamide methyl MEA, cocamide MEA, cocamide DEA, cocamide MIPA, lauramide MEA, lauramide DEA, lauramide MIPA, myristicamide MEA, myristicamide DEA, soyamide DEA, oleamide MIPA, stearamide MEA, stearamide DEA, oleamide DEA, tallowamide DEA, lauramide MIPA, tallowamide MEA, isostearamide DEA, isostearamide MEA and mixtures thereof; preferably wherein the fatty alkanolamide is selected from the group consisting of cocamide MEA, cocamide DEA, lauramide MEA, lauramide DEA, stearamide MEA, myristicamide DEA, stearamide DEA and mixtures thereof; most preferably wherein the fatty alkanolamide is cocamide MEA.

10. The personal cleansing composition of any of the preceding claims, wherein the hydrophobically modified ethoxylated methyl glucoside is selected from the group consisting of PEG-120 methyl glucose dioleate, PEG-120 methyl glucose trioleate, PEG-20 methyl glucose sesquistearate, PEG-20 methyl glucose distearate, PEG-80 methyl glucose laurate, PEG-20 methyl glucose sesquistearate, PEG-120 methyl glucose triisostearate, and mixtures thereof.

11. A personal cleansing composition according to any one of the preceding claims, wherein the weight ratio of the fatty alkanolamide to the hydrophobically modified ethoxylated methyl glucoside ranges from 2 to 12, preferably from 5 to 10, more preferably from 8 to 9.

12. The personal cleansing composition according to any one of the preceding claims, wherein the fatty alkanolamide comprises cocamide MEA and the hydrophobically modified ethoxylated methyl glucoside is selected from the group consisting of PEG-120 methyl glucose dioleate, PEG-120 methyl glucose trioleate and mixtures thereof, wherein the weight ratio of the fatty alkanolamide to the hydrophobically modified ethoxylated methyl glucoside ranges from 5 to 12, preferably from 7 to 10, more preferably from 8 to 9.

13. The personal cleansing composition of any of the preceding claims, wherein the preservative is selected from the group consisting of alkali metal metabisulfites, alkali metal sulfites, alkali metal bisulfites, alkali metal dithionites, and mixtures thereof.

14. The personal cleansing composition of any of the preceding claims, wherein the preservative is selected from the group consisting of sodium metabisulfite, sodium sulfite, sodium dithionite, potassium sulfite, sodium bisulfite, potassium bisulfite, and mixtures thereof.

15. A personal cleansing composition according to any one of the preceding claims, wherein the co-surfactant comprises a zwitterionic surfactant, wherein the zwitterionic surfactant comprises an alkyl betaine or an alkyl amidopropyl betaine, preferably wherein the zwitterionic surfactant is selected from the group consisting of cocamidopropyl betaine, lauramidopropyl betaine, coco betaine and mixtures thereof.

16. A personal cleansing composition according to any preceding claim, wherein the composition is free of direct dyes, oxidative dyes, parabens or mixtures thereof.

17. A method of increasing the stability of a personal cleansing composition with respect to phase, color and microbial stability, the method comprising the step of forming a personal cleansing composition according to any one of the preceding claims.

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