Preparation process and method for extracting maslinic acid of hawthorn

Abstract

The invention relates to the technical field of extraction of maslinic acid, and provides a preparation process for extracting maslinic acid of hawthorn, preparation equipment for extracting maslinic acid of hawthorn is adopted, the equipment comprises an extraction box body, a T-shaped plate is fixedly connected to the middle position of the upper surface of the extraction box body, and feeding cylinders are fixedly connected to the ends of the two horizontal parts of the T-shaped plate; feeding valves are fixedly connected to the lower surfaces of the feeding cylinders, feeding pipes are fixedly connected to the ends, deviating from the feeding cylinders, of the feeding valves, and the ends, deviating from the feeding valves, of the feeding pipes penetrate through the extraction box body and extend into the extraction box body. The falling amount of the extraction agent and the raw materials is controlled according to the proportion of the extraction agent and the raw materials, so that the proportion of the extraction agent and the raw materials entering the stirring box body meets the requirement, the quality of maslinic acid can meet the requirement, then a servo motor is started, and the servo motor is controlled to rotate forwards and backwards to drive a stirring rod to stir the extraction agent and the raw materials.

Description

Technical Field

[0001] The invention relates to the technical field of hawthorn acid extraction, and in particular to a preparation process and a method for extracting hawthorn hawthorn acid. Background Art

[0002] Maslinic acid is a pentacyclic triterpene acid that exists in many natural plants, especially hawthorn, red dates, loquat leaves and olives. It is highly safe for the human body. In recent years, it has been found that maslinic acid has multiple biological activities such as anti-cancer, antioxidant, anti-AIDS, antibacterial and anti-diabetic. Maslinic acid needs to be extracted during the production process. The extraction equipment includes a separatory funnel, an extraction column and an extraction tank, but all of them need to be stirred. Since the existing raw materials and extractants are mostly added directly into the extraction equipment, and the extractant and the raw materials are separated quickly, it is difficult to stir the extractant and the raw materials evenly, resulting in low extraction efficiency.

[0003] In the prior art, an extraction tank device for extracting and separating hawthorn acid with patent number CN215137070U includes a box body, an inner wall of which is provided with an annular groove, and a threaded rod is driven to rotate by starting a servo motor, and the threaded rod drives two mounting blocks to move toward or in opposite directions at the same time, and the mounting blocks drive the mounting frame to move up and down through the support rod, thereby driving the stirring roller to move up and down, expanding the stirring range, and the rotation of the threaded rod drives the sprocket wheel connected to the threaded rod by the chain drive to rotate, the sprocket wheel drives the driving wheel to rotate, the driving wheel drives the driven wheel to rotate, and the driven wheel drives the tank body and the stirring roller to rotate in opposite directions through the rotating rod, thereby accelerating the stirring speed and improving the stirring efficiency.

[0004] In the present invention, the stirring roller is moved up and down and the tank body and the stirring roller are rotated in opposite directions. Although the stirring speed can be accelerated and the stirring efficiency can be improved, the existing addition method is mostly manual during feeding, and it is difficult to accurately control the ratio between different extractants and raw materials, resulting in differences in the purity of the extracted maslinic acid, which in turn affects the quality of the maslinic acid. Summary of the invention

[0005] The invention provides a preparation process and method of maslinic acid extracted from hawthorn, which solves the problem of a preparation process and method of maslinic acid extracted from hawthorn in the related art.

[0006] The technical solution of the present invention is as follows:

[0007] A preparation process of hawthorn acid extracted from hawthorn, using a preparation device for hawthorn acid extracted from hawthorn, the device comprising an extraction box, a stirring box arranged inside the extraction box, two support plates symmetrically connected and fixed to the outer peripheral surface of the stirring box, one end of the support plate away from the stirring box is in sliding contact with the inner wall of the extraction box, a discharge valve is connected and fixed to a position below the outer peripheral surface of the stirring box, a servo motor is fixedly installed at the bottom of the extraction box, a connecting rod is connected and fixed to the output end of the servo motor, one end of the connecting rod away from the servo motor passes through the stirring box and is connected and fixed to a plurality of stirring rods, and the stirring rods are arranged in the stirring box;

[0008] A T-shaped plate is connected and fixed in the middle position of the upper surface of the extraction box, and the two horizontal ends of the T-shaped plate are connected and fixed to a feed barrel. A feed valve is connected and fixed to the lower surface of the feed barrel, and a feed pipe is connected and fixed to the end of the feed valve away from the feed barrel, and the end of the feed pipe away from the feed valve passes through the extraction box and extends into the extraction box.

[0009] Preferably, two support seats are installed and fixed at the bottom edge of the extraction box body, and the upper surfaces of the two support seats are rotatably connected with support wire columns, and the end of the support wire column away from the support seat passes through the support plate and extends to the upper side of the support plate, and the upper portion of the outer peripheral surface of the support wire column is processed with a thread, and the support plate is threadedly connected to the support wire column, and the first sprocket is installed and fixed at the lower portion of the outer peripheral surface of the two support wire columns, and the second sprocket is installed and fixed on the connecting rod, and the first sprocket and the second sprocket are connected by a chain transmission.

[0010] Preferably, one end of the support wire column extending to the upper side of the support plate is connected to a fixed limiting block.

[0011] Preferably, a vertical observation window is provided on the outer peripheral surface of the feed barrel, and scale lines are processed on the side of the observation window.

[0012] Preferably, a cabinet door is provided on the front of the extraction box body, a cabinet door is hinged inside the cabinet door, and a handle is connected and fixed to the cabinet door.

[0013] Preferably, a sealing ring is sleeved on the connecting rod, and the outer peripheral surface of the sealing ring is in contact with the stirring box.

[0014] A method for preparing equipment for extracting hawthorn acid comprises the following steps:

[0015] Step S1: crushing the hawthorn with a crusher and sieving it through 80-100 mesh;

[0016] Step S2: Pour the extractant and hawthorn powder into two feeding barrels respectively, observe the volumes of the extractant and raw materials through the observation window and the scale line, and then control the discharge of the two materials by turning the discharge valves, and control the amount of the two materials falling according to the ratio between the two materials, so that the ratio of the two materials entering the mixing box meets the requirements;

[0017] Step S3: opening the feed valve, feeding the extractant and hawthorn powder into the stirring box through the feed pipe, and the servo motor drives the stirring rod to rotate inside the stirring box through the connecting rod to stir the extractant and hawthorn powder inside the stirring box;

[0018] Step S4: Since the connecting rod is fixedly connected to the two second sprockets, the two second sprockets drive the corresponding first sprockets to rotate through the corresponding chains. Since the first sprocket is fixedly connected to the support wire column, the first sprocket drives the corresponding support wire column to rotate. Since the support wire column and the support plate are threadedly matched, the support wire column can push the support plate to move. Since the support plate is fixedly connected to the stirring box, the support wire column will push the support plate and the stirring box to move synchronously. At this time, the stirring rod is used to stir the extractant and hawthorn powder at different heights inside the stirring box.

[0019] Step S5: let it stand for 0.5-1.5h, open the cabinet door, take out the extract from the inside of the stirring box, and then open the discharge valve to take out the precipitate;

[0020] Step S6: taking the filtrate and reducing the pressure to recover ethanol to obtain a crude extract;

[0021] Step S7: adding the crude extract to a 70% ethanol solution to redissolve it to obtain a mixed solution;

[0022] Step S8: Place the mixed solution on an AB-8 macroporous adsorption resin column, first elute with water until it is colorless, then add a 60-90°C, 0.1-0.15 mol / L sodium bicarbonate solution for elution, collect the sodium bicarbonate eluate, adjust the pH to 3-5, filter, and dry the filter residue to obtain hawthorn acid.

[0023] Preferably, in step S2, the extractant is a 70% ethanol solution, and the ratio of the extractant to the hawthorn powder is 1:10.

[0024] The working principle and beneficial effects of the present invention are:

[0025] 1. In the present invention, two feeding barrels are arranged on the upper side of the extraction box, and the extractant and the raw material are poured into the two feeding barrels respectively. The discharge of the two is controlled by twisting the discharge valves, and the amount of the two falling is controlled according to the ratio between the two, so that the ratio of the two entering the stirring box reaches the requirement, and then the quality of the hawthorn acid can reach the requirement, and then the servo motor is started, and the connecting rod is driven to rotate by controlling the forward and reverse rotation of the servo motor, and the stirring rod is further driven to stir the extractant and the raw material, thereby accelerating the extraction efficiency.

[0026] 2. When the servo motor of the present invention rotates, the second sprocket will be driven to rotate, and further the first sprocket connected to the chain transmission will be driven to rotate, so that the supporting thread column can also rotate, and the supporting thread column is processed with threads, so the support plate will move up and down under the rotation of the supporting thread column, and further the mixing box can be moved up and down, thereby expanding the mixing range and further increasing the mixing efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] The present invention will be further described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0028] Figure 1 It is a three-dimensional schematic diagram of the structure of the present invention;

[0029] Figure 2 is a cross-sectional view of the structure of the present invention;

[0030] Figure 3 It is a three-dimensional schematic diagram of the stirring box in the structure of the present invention;

[0031] Figure 4 A top view of the chain, the first sprocket and the second sprocket in the structure of the present invention;

[0032] In the figure:

[0033] 1. Extraction box; 2. Mixing box; 3. Support plate; 4. Discharge valve; 5. Servo motor; 6. Connecting rod; 7. Mixing rod; 8. T-shaped plate; 9. Feed barrel; 10. Feed valve; 11. Feed pipe; 12. Support seat; 13. Support screw column; 14. First sprocket; 15. Chain; 16. Second sprocket; 17. Observation window; 18. Cabinet door; 19. Handle; 20. Sealing ring. DETAILED DESCRIPTION

[0034] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0035] Example 1

[0036] like Figure 1 , Figure 2 and Figure 3 As shown, a preparation process of hawthorn acid extracted from hawthorn is adopted, and a preparation equipment of hawthorn acid extracted from hawthorn is adopted, and the equipment comprises an extraction box 1, a cabinet door is opened on the front of the extraction box 1, a cabinet door 18 is hingedly connected in the extractant cabinet door, a handle 19 is connected and fixed to the extractant cabinet door 18, a stirring box 2 is arranged in the extractant extraction box 1, two support plates 3 are symmetrically connected and fixed to the outer peripheral surface of the extractant stirring box 2, one end of the extractant support plate 3 away from the stirring box 2 is in sliding contact with the inner wall of the extraction box 1, a discharge valve 4 is connected and fixed to the outer peripheral surface of the extractant stirring box 2 at a lower position, a servo motor 5 is fixedly installed at the bottom of the extractant extraction box 1, a connecting rod 6 is connected and fixed to the output end of the extractant servo motor 5, one end of the extractant connecting rod 6 away from the servo motor 5 passes through the stirring box 2 and is connected and fixed to a plurality of stirring rods 7, the extractant stirring rod 7 is arranged in the stirring box 2, a sealing ring 20 is sleeved on the extractant connecting rod 6, and the outer peripheral surface of the extractant sealing ring 20 is in contact with the stirring box 2.

[0037] In the present invention, by starting the servo motor 5, the servo motor 5 is controlled to rotate forward and reversely to drive the connecting rod 6 to rotate, and further drive the stirring rod 7 to stir the extractant and the raw material, thereby accelerating the extraction efficiency. After the extraction is completed, the handle 19 is pulled to open the cabinet door 18, and the extracted maslin acid is taken out from the discharge valve 4.

[0038] Example 2

[0039] like Figure 1 and Figure 2 As shown, based on the same concept as the above-mentioned embodiment 1, this embodiment further proposes that a T-shaped plate 8 is connected and fixed to the middle position of the upper surface of the extraction box body 1, and the two horizontal ends of the extractant T-shaped plate 8 are connected and fixed to the feeding cylinder 9, and the outer peripheral surface of the feeding cylinder 9 is provided with a vertical observation window 17, and the side of the extractant observation window 17 is processed with a scale line, and the lower surface of the extractant feeding cylinder 9 is connected and fixed to a feeding valve 10, and the end of the extractant feeding valve 10 away from the feeding cylinder 9 is connected and fixed to a feeding pipe 11, and the end of the extractant feeding pipe 11 away from the feeding valve 10 passes through the extraction box body 1 and extends into the extraction box body 1.

[0040] In the present invention, two feeding barrels 9 are arranged on the upper side of the extraction box 1, and are supported by a T-shaped plate 8 to increase its stability. The extractant and the raw material are poured into the two feeding barrels 9 respectively, and the volumes of the extractant and the raw material can be observed through the observation port and the scale line. Then, the discharge of the two is controlled by twisting the discharge valves, and the amount of the two falling is controlled according to the ratio between the two, so that the ratio of the two entering the stirring box 2 meets the requirements, and thus the quality of the hawthorn acid can meet the requirements.

[0041] like Figure 2 and Figure 4 As shown, based on the same concept as the above-mentioned embodiment 1, this embodiment further proposes that two support seats 12 are installed and fixed at the bottom edge position of the extractant extraction box body 1, and the upper surfaces of the two extractant support seats 12 are rotatably connected with support wire columns 13, and the end of the extractant support wire column 13 away from the support seat 12 penetrates the support plate 3 and extends to the upper side of the support plate 3. The upper position of the outer peripheral surface of the extractant support wire column 13 is processed with a thread, and the extractant support plate 3 is threadedly connected to the support wire column 13, and the lower position of the outer peripheral surface of the two extractant support wire columns 13 is installed and fixed with a first sprocket 14, and the second sprocket 16 is installed and fixed on the extractant connecting rod 6. The first extractant sprocket 14 and the second sprocket 16 are connected by a chain 15 for transmission, and the support wire column 13 extends to one end of the upper side of the support plate 3 and is connected and fixed to a limited position block.

[0042] In the present invention, when the servo motor 5 rotates, the second sprocket 16 will be driven to rotate, and further the first sprocket 14 connected to the chain 15 will be driven to rotate, so that the support wire column 13 can also rotate, and the support wire column 13 is processed with threads, so the support plate 3 will move up and down under the rotation of the support wire column 13, and further the stirring box 2 can be moved up and down, thereby expanding the stirring range and further increasing the stirring efficiency. Adding a limit block can limit the support plate 3 to prevent the support plate 3 from detaching from the support wire column 13 to cause damage to the equipment and affect the extraction of hawthorn acid.

[0043] Implementation Case 3

[0044] In combination with Example 1 and Example 2, further, Figure 1-4 As shown, a method for preparing a device for extracting hawthorn acid comprises the following steps:

[0045] Step S1: crushing the hawthorn with a crusher and sieving it through 80-100 mesh;

[0046] Step S2: pouring the extractant and hawthorn powder into two feeding barrels (9) respectively, wherein the extractant is a 70% ethanol solution, and the ratio of the extractant to the hawthorn powder is 1:10. The volumes of the extractant and the raw material can be observed through the observation window (17) and the scale line, and then the discharge of the two materials is controlled by twisting the discharge valves, and the amount of the two materials falling is controlled according to the ratio between the two materials, so that the ratio of the two materials entering the stirring box 2 meets the requirements;

[0047] Step S3: opening the feed valve (10), feeding the extractant and hawthorn powder into the interior of the stirring box (2) along the feed pipe (11), and the servo motor (5) drives the stirring rod (7) to rotate inside the stirring box (2) through the connecting rod (6) to stir the extractant and hawthorn powder inside the stirring box (2);

[0048] Step S4: Since the connecting rod (6) is fixedly connected to the two second sprockets (16), the two second sprockets (16) drive the corresponding first sprockets (14) to rotate through the corresponding chains (15); since the first sprocket (14) is fixedly connected to the supporting wire column (13), the first sprocket (14) drives the corresponding supporting wire column (13) to rotate; since the supporting wire column (13) and the supporting plate (3) are threadedly matched, the supporting wire column (13) can push the supporting plate (3) to move; since the supporting plate (3) is fixedly connected to the stirring box (2), the supporting wire column (13) will push the supporting plate (3) and the stirring box (2) to move synchronously; at this time, the stirring rod (7) is used to stir the extractant and hawthorn powder at different heights inside the stirring box (2);

[0049] Step S5: let it stand for 0.5-1.5 hours, open the cabinet door (18), take out the extract from the inside of the stirring box (2), and then open the discharge valve (4) to take out the precipitate;

[0050] Step S6: taking the filtrate and reducing the pressure to recover ethanol to obtain a crude extract;

[0051] Step S7: adding the crude extract to a 70% ethanol solution to redissolve it to obtain a mixed solution;

[0052] Step S8: Place the mixed solution on an AB-8 macroporous adsorption resin column, first elute with water until it is colorless, then add a 60-90°C, 0.1-0.15 mol / L sodium bicarbonate solution for elution, collect the sodium bicarbonate eluate, adjust the pH to 3-5, filter, and dry the filter residue to obtain hawthorn acid.

[0053] The above are only preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A process for preparing hawthorn acid by extracting hawthorn, characterized in that: A preparation device for maslinic acid extracted from hawthorn is provided, the device comprising an extraction box (1), a stirring box (2) is arranged inside the extraction box (1), two support plates (3) are symmetrically connected and fixed to the outer peripheral surface of the stirring box (2), one end of the support plate (3) away from the stirring box (2) is in sliding contact with the inner wall of the extraction box (1), a discharge valve (4) is connected and fixed to the outer peripheral surface of the stirring box (2) at a position below, a servo motor (5) is fixedly installed at the bottom of the extraction box (1), a connecting rod (6) is connected and fixed to the output end of the servo motor (5), and one end of the connecting rod (6) away from the servo motor (5) passes through the stirring box (2) and is connected and fixed to a plurality of stirring rods (7), and the stirring rods (7) are arranged in the stirring box (2); A T-shaped plate (8) is connected and fixed at the middle position of the upper surface of the extraction box (1), and a feed barrel (9) is connected and fixed to both horizontal ends of the T-shaped plate (8). A feed valve (10) is connected and fixed to the lower surface of the feed barrel (9), and a feed pipe (11) is connected and fixed to the end of the feed valve (10) facing away from the feed barrel (9), and the end of the feed pipe (11) facing away from the feed valve (10) passes through the extraction box (1) and extends into the extraction box (1).

2. The preparation equipment for extracting hawthorn acid according to claim 1, characterized in that: Two support seats (12) are fixedly installed at the bottom edge of the extraction box body (1), and the upper surfaces of the two support seats (12) are rotatably connected with support wire columns (13). The end of the support wire column (13) away from the support seat (12) passes through the support plate (3) and extends to the upper side of the support plate (3). The upper portion of the outer peripheral surface of the support wire column (13) is processed with a thread. The support plate (3) is threadedly connected to the support wire column (13). The lower portion of the outer peripheral surface of the two support wire columns (13) is fixedly installed with a first sprocket (14), and the connecting rod (6) is fixedly installed with a second sprocket (16). The first sprocket (14) and the second sprocket (16) are connected by a chain (15).

3. The preparation equipment for extracting hawthorn acid according to claim 2, characterized in that, The support wire column (13) extends to one end of the upper side of the support plate (3) and is connected to a fixed limiting block.

4. The preparation equipment for extracting hawthorn acid according to claim 1, characterized in that: A vertical observation window (17) is provided on the outer peripheral surface of the feed barrel (9), and scale lines are processed on the side of the observation window (17).

5. The preparation equipment for extracting hawthorn acid according to claim 1, characterized in that: The front of the extraction box (1) is provided with a cabinet door, a cabinet door (18) is hinged inside the cabinet door, and a handle (19) is connected and fixed to the cabinet door (18).

6. The preparation equipment for extracting hawthorn acid according to claim 1, characterized in that: The connecting rod (6) is sleeved with a sealing ring (20), and the outer peripheral surface of the sealing ring (20) is in contact with the stirring box (2).

7. The method for preparing the equipment for extracting hawthorn acid according to any one of claims 1 to 6, characterized in that: The following steps are involved: Step S1: crushing the hawthorn with a crusher and sieving it through 80-100 mesh; Step S2: Pour the extractant and hawthorn powder into two feed barrels (9) respectively, observe the volumes of the extractant and raw materials through the observation window (17) and the scale lines, and then control the discharge of the two materials by turning the discharge valves, and control the amount of the two materials falling according to the ratio between the two materials, so that the ratio of the two materials entering the stirring box 2 meets the requirements; Step S3: opening the feed valve (10), feeding the extractant and hawthorn powder into the interior of the stirring box (2) along the feed pipe (11), and the servo motor (5) drives the stirring rod (7) to rotate inside the stirring box (2) through the connecting rod (6) to stir the extractant and hawthorn powder inside the stirring box (2); Step S4: Since the connecting rod (6) is fixedly connected to the two second sprockets (16), the two second sprockets (16) drive the corresponding first sprockets (14) to rotate through the corresponding chains (15); since the first sprocket (14) is fixedly connected to the supporting wire column (13), the first sprocket (14) drives the corresponding supporting wire column (13) to rotate; since the supporting wire column (13) and the supporting plate (3) are threadedly matched, the supporting wire column (13) can push the supporting plate (3) to move; since the supporting plate (3) is fixedly connected to the stirring box (2), the supporting wire column (13) will push the supporting plate (3) and the stirring box (2) to move synchronously; at this time, the stirring rod (7) is used to stir the extractant and hawthorn powder at different heights inside the stirring box (2); Step S5: let it stand for 0.5-1.5 hours, open the cabinet door (18), take out the extract from the inside of the stirring box (2), and then open the discharge valve (4) to take out the precipitate; Step S6: taking the filtrate and reducing the pressure to recover ethanol to obtain a crude extract; Step S7: adding the crude extract to a 70% ethanol solution to redissolve it to obtain a mixed solution; Step S8: Place the mixed solution on an AB-8 macroporous adsorption resin column, first elute with water until it is colorless, then add a 60-90° C., 0.1-0.15 mol / L sodium bicarbonate solution for elution, collect the sodium bicarbonate eluate, adjust the pH to 3-5, filter, and dry the filter residue to obtain hawthorn acid.

8. The preparation equipment for extracting hawthorn acid according to claim 7, characterized in that: In step S2, the extractant is 70% ethanol solution, and the ratio of the extractant to the hawthorn powder is 1:10.

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