Implantable dialysis device with temperature control function

Abstract

The invention provides an implantable dialysis device with a temperature control function, and belongs to the technical field of dialysis, the implantable dialysis device comprises an implantable dialysis body and an external temperature control base, the implantable dialysis body comprises a blood temporary storage port and a blood vessel communicating pipe, the blood temporary storage port is composed of a port seat and a puncture part, the port seat comprises a nickel-titanium alloy middle layer and an outer coating layer, and the outer coating layer comprises a nickel-titanium alloy outer coating layer. The puncture part comprises a stent membrane which can be punctured by the puncture needle, and the blood vessel communicating pipe is located at at least one end of the blood temporary storage port, communicates with the blood temporary storage port and is used for being connected with an artery or vein blood vessel; the external temperature control base comprises an electrified coil, and an electromagnetic field can be formed between the electrified coil and the nickel-titanium alloy middle layer to heat the nickel-titanium alloy middle layer; the device not only can replace internal fistula in a traditional dialysis mode, but also can heat subcutaneously to a proper temperature based on an electromagnetic heating principle, so that the dialysis quality is improved, and the risk of related complications caused by dialysis is reduced or avoided.

Description

Technical Field

[0001] The invention belongs to the technical field of dialysis, and in particular relates to an implantable dialysis device with a temperature control function. Background Art

[0002] Hemodialysis, abbreviated as HD, is a renal replacement therapy; the principle is to extract the patient's blood from the body, filter it through a dialyzer (similar to an artificial kidney), remove toxins, waste, excess water and electrolytes in the blood, and then return the purified blood to the body.

[0003] At present, dialysis is mainly performed by establishing a veno-arterial fistula in the patient's forearm or upper arm. One of the shortcomings of this method is that it takes some time (generally several weeks to several months) for the fistula to mature after surgery, otherwise the blood flow for dialysis cannot be achieved. The second shortcoming is that regular and frequent punctures can easily cause damage to the blood vessels and tissues around the fistula, increasing the risk of complications. In this regard, an invention patent with application number 202111601289.9 discloses an implantable dialysis port, which includes two puncture ports connected by artificial blood vessels, and the two puncture ports are respectively connected to the vein and artery through artificial blood vessels. After analyzing the structure, although it can solve the shortcomings of fistula establishment, it has the following shortcomings in clinical use.

[0004] (1) Blood vessels are prone to thrombosis and hyperplasia, which can lead to complications such as ischemia in the blood supply area.

[0005] (2) If foreign objects are left in place for a long time, there is a chance of infection.

[0006] Based on the above analysis, this application designs an implantable dialysis device with temperature control function. Summary of the invention

[0007] The object of the present invention is to provide an implantable dialysis device with a temperature control function to solve at least one of the shortcomings of existing dialysis ports.

[0008] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: an implantable dialysis device with temperature control function: comprising an implantable dialysis body and an external temperature control base, the implantable dialysis body comprising a blood cache port and a vascular connecting tube, the blood cache port being composed of a port seat and a puncture part, wherein the port seat comprises a nickel-titanium alloy middle layer and an outer coating layer, the puncture part comprises a stent membrane that can be punctured by a puncture needle, the vascular connecting tube is located at at least one end of the blood cache port and is connected to the blood cache port, the vascular connecting tube is used to connect an artery or a vein; the external temperature control base comprises an energized coil, when the external temperature control base is placed on the implantable dialysis body, an electromagnetic field can be formed between the energized coil and the nickel-titanium alloy middle layer to heat the nickel-titanium alloy middle layer.

[0009] As a preferred embodiment of the present application, the blood buffer port is a semi-ellipsoidal structure, and the vascular connecting tube is located at one axial end of the blood buffer port and forms an acute angle α with the axial direction of the blood buffer port to ensure the formation of a smooth blood circulation channel that conforms to dynamic fluid mechanics.

[0010] As a preferred solution of the present application, the acute angle α has a value range of 30-60°.

[0011] As a preferred embodiment of the present application, the external temperature control base includes a shell, on which at least a power supply compartment and a coil compartment are provided, the power supply compartment has a built-in power supply and a temperature controller, the powered coil is placed in the coil compartment, and the output current of the power supply is adjusted by the temperature controller to thereby adjust the magnetic field strength of the powered coil.

[0012] As a preferred embodiment of the present application, the power supply compartment and the coil compartment are arranged in an upper and lower orientation and the power supply compartment is located at the upper end of the coil compartment. A sunken groove is provided at the bottom of the shell, and the size of the sunken groove is slightly larger than the size of the implantable dialysis body. The shell can be covered above the implantable dialysis body through the sunken groove.

[0013] As a preferred solution of the present application, the temperature controller is a potentiometer.

[0014] As a preferred solution of the present application, metal nanoparticles are provided in the port seat, and the metal nanoparticles are located between the nickel-titanium alloy middle layer and the outer coating layer, or the metal nanoparticles are encapsulated in the outer coating layer.

[0015] As a preferred embodiment of the present application, the blood vessel connecting tube is a skeleton tube or an artificial blood vessel. When it is a skeleton tube, the skeleton tube comprises a horizontal tube section and a branch tube section extending therefrom, and the horizontal tube section can be built into the blood vessel, and the branch tube section is connected to the blood buffer port; when it is an artificial blood vessel, the end of the artificial blood vessel is provided with an anastomosis port for anastomosis with the blood vessel.

[0016] As a preferred solution of the present application, the skeleton tube is made of nickel-titanium alloy, and a coating layer is provided on the outside of the branch tube section of the skeleton tube, and the coating layer is any one of medical silica gel or medical gel.

[0017] As a preferred solution of the present application, a fluorescent marking structure is provided at the connection between the port seat and the puncture part, and the puncture part is positioned by the fluorescent marking structure.

[0018] Compared with the existing dialysis technology, the beneficial effects of the present invention include: The device of the present application comprises an implantable dialysis body and an external temperature control base, wherein the implantable dialysis body replaces the establishment of an internal fistula in the traditional dialysis method, that is, the dialysis operation is realized without the establishment of an internal fistula, and the blood buffer port is connected to the vein or artery through the vascular connecting tube to make the blood buffer port a branch of the blood vessel, so that under the action of blood pressure, the blood pressure and flow rate in the blood buffer port are stable to meet the dialysis needs, and at the same time, the port seat of the blood buffer port comprises a nickel-titanium alloy middle layer, so that on the one hand, the hard structure of the nickel-titanium alloy can be used to limit the puncture needle to avoid the puncture needle penetrating the blood buffer port, and on the other hand, the metal properties of the nickel-titanium alloy are used to use it as an iron core; The embedded temperature control base has a built-in energized coil, through which the nickel-titanium alloy serving as the iron core can be heated to increase vasodilation, improve subcutaneous blood fluidity, viscosity, cell metabolism rate and tissue softness, etc., thereby reducing the occurrence of subcutaneous tissue inflammation, hyperplasia and thrombosis, and achieving the purpose of physical prevention and treatment. It can be seen that the implantable dialysis device with temperature control function in this scheme can not only replace the fistula in the traditional dialysis method, but also can heat the subcutaneous tissue to a suitable temperature based on the principle of electromagnetic heating, thereby improving the dialysis quality while reducing or avoiding the risk of dialysis-related complications, solving the existing deficiencies, meeting the existing clinical needs, and having certain promotion value. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 A schematic diagram of the main structure of an implantable dialysis device provided by the present invention, in which a skeleton tube is provided at one end of the blood buffer port as a blood vessel connecting tube.

[0020] Figure 2 The present invention provides Figure 1 Schematic diagram of the cross-sectional structure along the AA direction.

[0021] Figure 3 The present invention provides Figure 2 A local enlarged schematic diagram of point A in the middle.

[0022] Figure 4 The present invention provides Figure 1A schematic longitudinal section of an implantable dialysis device with temperature control function.

[0023] Figure 5 The present invention provides Figure 4 A local enlarged schematic diagram of point B in the middle.

[0024] Figure 6 The main structural schematic diagram of an implantable dialysis device with a temperature control function in which the blood vessel connecting tube provided by the present invention is an artificial blood vessel.

[0025] Figure 7 The present invention provides Figure 6 A partial enlarged schematic diagram of point D in the middle.

[0026] Figure 8 This is a schematic diagram of the overall structure of the external temperature control base provided by the present invention.

[0027] Fig. 9 This is a schematic diagram of the overall structure of the bottom of the external temperature control base provided by the present invention.

[0028] Fig.10 A schematic diagram of the main structure of an implantable dialysis device with a temperature control function, in which artificial blood vessels are respectively provided at both ends of the blood buffer port provided by the present invention as blood vessel connecting tubes.

[0029] Fig.11 A schematic diagram of the main structure of an implantable dialysis device with a temperature control function, in which skeleton tubes are respectively provided at both ends of the blood buffer port provided by the present invention as blood vessel connecting tubes.

[0030] Reference numerals 10 is a blood buffer port; 11 is a port seat; 111 is a nickel-titanium alloy middle layer; 112 is an outer coating layer; 113 is metal nanoparticles; 12 is a puncture part; 13 is a fluorescent ring; 20 is a blood vessel connecting tube; 21 is a horizontal pipe section; 22 is a branch pipe section; 23 is a skeleton tube 23; 24 is a coating layer; 23 is an artificial blood vessel; 30 is an external temperature control base; 31 is a temperature control board; 32 is a power supply compartment; 33 is a coil compartment; 34 is a sinking groove. DETAILED DESCRIPTION

[0031] The present invention will be further described in detail below in conjunction with specific implementations and with reference to the accompanying drawings. It should be emphasized that the following description is merely exemplary and is not intended to limit the scope of the present invention and its application.

[0032] Embodiment 1: This embodiment provides an implantable dialysis device with a temperature control function, the device comprises an implantable dialysis body and an external temperature control base 30, the implantable dialysis body comprises a blood buffer port 10 and a blood vessel connecting tube 20, the blood buffer port 10 comprises a port seat 11 and a puncture portion 12, wherein the port seat 11 comprises a nickel-titanium alloy middle layer 111 and an outer coating layer 112, the puncture portion 12 comprises a stent membrane that can be punctured by a puncture needle, that is, the entire puncture portion 12 is set as a stent membrane structure to expand the puncture area; the blood vessel connecting tube 20 is located at one axial end of the blood buffer port 10 and is connected to the blood buffer port 10, the blood vessel connecting tube 20 is used to connect an artery or a vein to enter Blood shunting; the external temperature control base 30 includes a powered coil. When the external temperature control base 30 is placed on the implantable dialysis body, an electromagnetic field can be formed between the powered coil and the nickel-titanium alloy middle layer 111 to heat the nickel-titanium alloy middle layer 111. It can be understood that according to temperature requirements, the number of nickel-titanium alloy layers can be set to multiple layers, and the thickness of the base can be controlled within 3 mm; in this embodiment, the heating temperature of the nickel-titanium alloy middle layer 111 is controlled at about 40°C, which can increase vasodilation and thereby reduce the occurrence of subcutaneous tissue inflammation, hyperplasia and thrombosis, thereby achieving the purpose of physical prevention and treatment, and can also meet the heat energy output requirements based on the electromagnetic heating principle under this structure.

[0033] It can be understood that at least the inner wall surface of the blood buffer port 10 is coated with a coating that utilizes biocompatibility and anticoagulant effects, which can prevent thrombosis during long-term use and improve safety of use.

[0034] When in use, the dialysis device can be implanted as a whole in the patient's body, wherein the vascular connecting tube 20 can be connected to the artery or vein, and the blood buffer port 10 is used as a blood buffer area for extracting and returning blood through puncture. The device replaces the establishment of fistula in the traditional dialysis method, that is, it realizes dialysis operation without establishing fistula. Moreover, the blood vessel connecting tube 20 is connected to the vein or artery, so that the blood buffer port 10 becomes a branch of the blood vessel. Under the action of blood pressure, the blood pressure and blood flow in the blood buffer port 10 are stable to meet the dialysis needs. Any position of the puncture part 12 can be used as the puncture area, which reduces the difficulty of puncture. The puncture needle can enter the blood buffer port 10 through the puncture area to extract blood or return blood. In addition, a nickel-titanium alloy middle layer 111 is provided in the port seat 11 of the blood buffer port 10. On the one hand, the hard structure of nickel-titanium alloy can be used to limit the puncture needle to prevent the puncture needle from penetrating the blood buffer port 10. On the other hand, the metal properties of nickel-titanium alloy are used to serve as an iron core. The external temperature control base 30 is placed at the corresponding position of the patient's limb where the implantable dialysis body is buried, and the energized coil heats the nickel-titanium alloy serving as the iron core. It can be seen that the implantable dialysis device with temperature control function in this embodiment can not only replace the fistula in the traditional dialysis method, without worrying about frequent punctures causing damage to surrounding blood vessels and tissues, and without waiting for a long period after surgery to meet dialysis needs, but also can heat the subcutaneous tissue to a suitable temperature based on the principle of electromagnetic heating, thereby improving the dialysis quality while reducing or avoiding the risk of dialysis-related complications, improving patient satisfaction, and reducing the difficulty of clinical work.

[0035] like Figure 1-2 As shown, the blood buffer port 10 is a semi-ellipsoidal structure. Specifically, the height of the semi-ellipsoidal structure is 9-11mm, the length is 29-31mm, and the width is 14-16mm. The puncture portion 12 is a cover structure with a top arc surface composed of a stent membrane. In this embodiment, the stent membrane is preferably made of medical silicone with strong biocompatibility. The use of silicone as the material of the stent membrane satisfies the requirement that it serves as a skeleton and can be penetrated by a puncture needle. It can be understood that the skeleton membrane constituting the puncture portion 12 is used as a puncture area as a whole. This increases the puncture area and improves the success rate of puncture on the one hand, and simplifies the structure on the other hand. The port seat 11 can be a plate-like structure or a groove structure. In this embodiment, the port seat 11 is preferably provided with an outer edge extending upward on the remaining sides of the bottom plate except for the side connected to the blood vessel connecting tube 20, such as Figure 3 As shown, the outer edge is used to strengthen the strength of the blood vessel buffer port on the one hand, and to facilitate the connection of the puncture part 12 on the other hand.

[0036] The port seat 11 is composed of a nickel-titanium alloy middle layer 111 and an outer coating layer 112. The nickel-titanium alloy middle layer 111 is located at the center. Figure 3As shown, the material of the outer coating layer 112 is any one of medical silicone or medical gel with high biocompatibility. In this embodiment, silicone that is the same material as the stent membrane is preferably used, so that the port seat 11 and the puncture part 12 can be conveniently designed as an integral (integrated) structure through silicone.

[0037] Metal nanoparticles 113 are provided in the port seat, and the metal nanoparticles 113 are preferably Fe3O4 nanoparticles, such as Figure 3 As shown; the Fe3O4 nanoparticles can be arranged in the interlayer between the nickel-titanium alloy middle layer 111 and the outer coating layer 112, or can be encapsulated in the outer coating layer 112. The use of the nanoparticles in combination with the nickel-titanium alloy can enhance the ferromagnetism of the port seat, thereby enhancing the output energy of the port seat 11 in the electromagnetic heating principle to meet actual needs; it should be noted that the addition amount of the Fe3O4 nanoparticles is controlled within a safe range and does not affect MRI imaging.

[0038] The vascular connecting tube 20 is located at one end of the axial direction of the blood buffer port 10 and forms an acute angle α with the axial direction of the blood buffer port 10 to ensure the formation of a smooth blood circulation channel that conforms to dynamic fluid mechanics. In this embodiment, the value range of the acute angle α is preferably 30-60°; under the action of blood pressure, the blood flowing through the blood vessel can be diverted into the vascular connecting tube 20 and then into the blood buffer port 10. The setting of this angle can ensure that the blood at the diversion point meets the needs of dialysis. It has been measured that at this angle, the blood in the blood buffer port 10 can be circulated and replaced once within 1 minute, thereby avoiding the accumulation of blood in the blood buffer port 10, thereby affecting the dialysis effect and causing vascular thrombosis events.

[0039] The blood vessel connecting tube 20 is a skeleton tube 23 or an artificial blood vessel 23. When it is a skeleton tube 23, the skeleton tube 23 includes a horizontal tube section 21 and a branch tube section 22 extending therefrom. Figure 1 As shown in Figure 4, the horizontal tube section 21 can be built into the blood vessel to expand the blood vessel and ensure stable blood flow. The branch tube section 22 is connected to the blood buffer port 10 to transport the blood diverted from the blood vessel to the blood buffer port 10. It can be understood that the horizontal section is placed in the blood vessel. In order to avoid arterial or venous thrombosis and the difficulty of handling the tube port after extubation, the diameter of the horizontal section is preferably set to about 3 mm and the length is about 11 mm. When it is an artificial blood vessel 23, the end of the artificial blood vessel 23 is provided with an anastomosis for anastomosis with an artery or vein, and the anastomosis is connected to the vein or artery by suturing. Figure 6-7 shown.

[0040] The branch tube section 22 of the skeleton tube 23 is provided with a coating layer 24 on the outside. The coating layer 24 is any one of medical silicone or medical gel. In this embodiment, medical silicone is preferably used. This facilitates the skeleton tube 23 to be connected to the blood buffer port 10 to form a whole (the outer periphery of the blood buffer port 10 is coated with silicone), and can also avoid direct contact between the skeleton tube 23 and the tissue to cause tissue damage or incompatibility. The skeleton tube 23 is made of at least one of nickel-titanium alloy and polymer. In this embodiment, nickel-titanium alloy is preferably used. The nickel-titanium alloy as the iron core can further utilize the principle of electromagnetic heating to output heat energy to improve the vascular expansion performance, avoid thrombosis and hyperplasia formation, and at the same time, play an anti-inflammatory role.

[0041] A fluorescent marking structure is provided at the connection between the port seat 11 and the puncture part 12, through which the puncture part 12 is positioned, which is particularly suitable for environments with dim light; this facilitates medical staff to perform accurate punctures. It is understandable that, when necessary, a corresponding external fluorescence detector can be used.

[0042] The fluorescent marking structure is a closed or open-loop or dot-shaped fluorescent ring 13 formed by coating or encapsulating medical fluorescent material on the contact surface of the port seat 11 or the puncture portion 12. The present embodiment is preferably an open-loop fluorescent ring 13 composed of fluorescent material encapsulated on the upper end surface of the supporting layer of the port seat 11, wherein the fluorescent material is preferably an existing medical fluorescent agent.

[0043] like Figure 8-9 As shown, it is a structural schematic diagram of an external temperature control base 30 provided in this embodiment. The external temperature control base 30 is an independent structure, which is used in combination with the implantable dialysis body, and heats the implantable dialysis body in a non-contact manner based on the principle of electromagnetic heating; the external temperature control base 30 includes a shell, and the shell is provided with at least a power supply compartment 32 and a coil compartment 33. The power supply compartment 32 is equipped with a power supply and a temperature controller, and the energized coil is placed in the coil compartment 33 (not shown in the figure). The output current of the power supply is adjusted by the temperature controller to adjust the magnetic field strength of the energized coil. It can be understood that the number of turns, wire diameter and material of the energized coil can be selected according to actual needs, and this embodiment will not be repeated here, so as to meet the required heat energy output of the nickel-titanium alloy with limited size; the power supply unit can be a DC power supply or an AC power supply. In this embodiment, a DC battery is preferably used as the power supply. The DC battery is installed in the battery compartment and connected to the energized coil through the temperature controller.

[0044] The power supply compartment 32 and the coil compartment 33 are arranged in an upper and lower position, and the power supply compartment 32 is located at the upper end of the coil compartment 33. Fig. 9As shown; a sinking groove 34 is provided at the bottom of the shell, i.e., at a position corresponding to the coil compartment 33, and the size of the sinking groove 34 is larger than the size of the implantable dialysis body. The shell can be covered above the implantable dialysis body through the sinking groove 34. Specifically, the size of the sinking groove 34 is about 1 mm larger than the size of the implantable dialysis body, so as not to interfere with the use state of the implantable dialysis body; when in use, the external temperature control base 30 is clamped on the implantable dialysis body through the cooperation of the sinking groove 34, so that on the one hand, the risk of the external temperature control base 30 falling can be reduced, and on the other hand, the horizontal pipe section on the implantable dialysis body and the nickel-titanium alloy on the port seat can be located in the magnetic field of the energized coil; it can be understood that in order to improve the stability of the installation of the external temperature control base 30, it is preferred to provide a fixing member such as a strap on the shell (not shown in the figure), and the external temperature control base 30 is bound to the corresponding position of the patient, such as the forearm or upper arm, by the fixing member, specifically based on the installation position of the implantable dialysis body.

[0045] It can be understood that in order to facilitate the control of the magnetic field strength, a temperature control board 31 is preferably provided outside the shell, and the temperature control board 31 is provided with control buttons such as thermostat adjustment and switch.

[0046] The temperature controller can be a microcontroller or a potentiometer. Since the temperature output by the nickel-titanium alloy in the structure of this embodiment is limited and easy to control, a potentiometer is selected as the temperature controller. The specific model and parameters of the potentiometer are selected according to actual needs.

[0047] In addition, it should be noted that the external temperature control base 30 and the implantable dialysis body can be used in pairs, or can be used flexibly in a one-to-many manner.

[0048] Embodiment 2: This embodiment provides an implantable dialysis device with a temperature control function of another structure, which includes an implantable dialysis body and an external temperature control base 30; the implantable dialysis body includes a blood buffer port 10 and a blood vessel connecting tube 20, the blood buffer port 10 is composed of a port seat 11 and a puncture portion 12, wherein the port seat 11 includes a nickel-titanium alloy middle layer 111 and an outer coating layer 112, and the puncture portion 12 includes a stent membrane that can be punctured by a puncture needle; the external temperature control base 30 includes an energized coil, and when the external temperature control base 30 is placed on the implantable dialysis body, an electromagnetic field can be formed between the energized coil and the nickel-titanium alloy middle layer 111 to heat the nickel-titanium alloy middle layer 111; the difference from Embodiment 1 is that blood vessel connecting tubes 20 connected to the blood buffer port 10 are respectively provided at both ends of the axial opposite ends thereof, and the blood vessel connecting tube 20 is used to connect arteries or veins, such as Figure 10-11As shown, the dialysis device of this structure forms an inlet and an outlet blood circulation channel through the connection between the two blood vessel connecting tubes 20 and the blood buffer port 10. Compared with Example 1, the blood in and out of this device adopts independent channels, which avoids the occurrence of blood retention in the blood buffer port 10, and can effectively improve the quality and efficiency of hemodialysis.

[0049] In this embodiment, the specific structures of the blood vessel connecting tube 20, the blood buffer port 10 and the external temperature control base 30 are the same as those in the above-mentioned embodiment 1, and will not be described in detail in this embodiment.

[0050] In this embodiment, the dialysis device with this structure is particularly suitable for arteries.

[0051] What is described above is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical scheme and inventive concept of the present invention within the technical scope disclosed by the present invention, which should be covered by the protection scope of the present invention.

Claims

1. An implantable dialysis device with temperature control function, characterized in that: The invention comprises an implantable dialysis body and an external temperature control base, wherein the implantable dialysis body comprises a blood buffer port and a blood vessel connecting tube, wherein the blood buffer port is composed of a port seat and a puncture part, wherein the port seat comprises a nickel-titanium alloy middle layer and an outer coating layer, wherein the puncture part comprises a stent membrane which can be punctured by a puncture needle, and the blood vessel connecting tube is located at at least one end of the blood buffer port and is connected to the blood buffer port, and the blood vessel connecting tube is used to connect an artery or a vein; the external temperature control base comprises an energized coil, and when the external temperature control base is placed on the implantable dialysis body, an electromagnetic field can be formed between the energized coil and the nickel-titanium alloy middle layer to heat the nickel-titanium alloy middle layer.

2. The implantable dialysis device with temperature control function according to claim 1, characterized in that: The blood buffer port is a semi-ellipsoidal structure, and the blood vessel connecting tube is located at one axial end of the blood buffer port and forms an acute angle α with the axial direction of the blood buffer port.

3. The implantable dialysis device with temperature control function according to claim 2, characterized in that: The acute angle α has a value range of 30-60°.

4. The implantable dialysis device with temperature control function according to claim 1, characterized in that: The external temperature control base includes a shell, which is provided with at least a power supply compartment and a coil compartment. The power supply compartment has a built-in power supply and a temperature controller. The powered coil is placed in the coil compartment. The output current of the power supply is adjusted by the temperature controller to adjust the magnetic field strength of the powered coil.

5. The implantable dialysis device with temperature control function according to claim 4, characterized in that: The power supply compartment and the coil compartment are arranged in an upper and lower position and the power supply compartment is located at the upper end of the coil compartment. A sunken groove is provided at the bottom of the shell. The size of the sunken groove is larger than the size of the implantable dialysis body. The shell can be covered above the implantable dialysis body through the sunken groove.

6. The implantable dialysis device with temperature control function according to claim 4, characterized in that: The temperature controller is a potentiometer.

7. The implantable dialysis device with temperature control function according to claim 1, characterized in that: Metal nanoparticles are arranged in the port seat, and the metal nanoparticles are located between the nickel-titanium alloy middle layer and the outer coating layer, or the metal nanoparticles are encapsulated in the outer coating layer.

8. The implantable dialysis device with temperature control function according to claim 1, characterized in that: The blood vessel connecting tube is a skeleton tube or an artificial blood vessel. When it is a skeleton tube, the skeleton tube comprises a horizontal tube section and a branch tube section extending therefrom. The horizontal tube section can be built into the blood vessel, and the branch tube section is connected to the blood buffer port. When it is an artificial blood vessel, the end of the artificial blood vessel is provided with an anastomosis port for anastomosis with the blood vessel.

9. The implantable dialysis device with temperature control function according to claim 8, characterized in that: The skeleton tube is made of nickel-titanium alloy, and a coating layer is provided outside the branch tube section of the skeleton tube, and the coating layer is any one of medical silica gel or medical gel.

10. The implantable dialysis device with temperature control function according to claim 1, characterized in that: A fluorescent marking structure is provided at the connection between the port seat and the puncture portion.

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