Oxytetracycline hydrochloride wet powder granulator

Abstract

The invention relates to the technical field of oxytetracycline hydrochloride granulation, in particular to an oxytetracycline hydrochloride wet powder granulator which comprises a pressure-bearing heat release mechanism, a driving mechanism arranged on the pressure-bearing heat release mechanism and a crystallization centrifugal drying mechanism arranged in the pressure-bearing heat release mechanism. The grain thickness adjusting mechanism is arranged on the crystallization centrifugal draining mechanism; and the air inlet assembly is arranged in the crystallization centrifugal draining mechanism. The inner bin is arranged, the uniformly distributed holes are formed in the inner wall of the inner bin, and the granulation column heads capable of movably extending are arranged in the holes, so that after a wet product is input into the cavity formed by the inner bin and the base, the cavity separated by the feeding piece is obtained, and the wet product can be centrifugally drained; and the materials which are gradually drained can be poured into the holes along with regular lifting of the feeding piece and finally form particles under repeated extrusion of the feeding piece, and the granulation size can be selectively adjusted under regulation and control of the granulation piece.

Description

Technical Field

[0001] The invention relates to the technical field of oxytetracycline hydrochloride granulation, in particular to an oxytetracycline hydrochloride wet powder granulator. Background Art

[0002] Oxytetracycline hydrochloride is a yellow crystalline powder which is hygroscopic. Since oxytetracycline hydrochloride is a broad-spectrum antibacterial agent, many rickettsiae, mycoplasmas, chlamydiae, spirochetes, amoebas and some malarial parasites are also sensitive to it.

[0003] Since oxytetracycline hydrochloride needs to be extracted from spores or molds, the spores and molds need to be fermented and filtered multiple times before the wet products can be produced. However, according to different needs, the current equipment for preparing wet products into granules has certain defects. The same type of granulation equipment can only make granules of specified size for crystalline powder wet products, and cannot select the size of granulation. In addition, if the wet products cannot be completely processed in a single granulation, the injection of subsequent re-processed wet products will be hindered due to the influence of existing equipment.

[0004] In view of this, a oxytetracycline hydrochloride wet powder granulator was designed to solve the above problems. Summary of the invention

[0005] The present invention aims to solve one of the technical problems existing in the prior art or related technology.

[0006] To this end, the technical solution adopted in the present invention is:

[0007] A oxytetracycline hydrochloride wet powder granulator, comprising a pressure-bearing heat release mechanism, a driving mechanism arranged on the pressure-bearing heat release mechanism, a crystallization centrifugal drying control mechanism arranged in the pressure-bearing heat release mechanism, a particle thickness adjustment mechanism arranged on the crystallization centrifugal drying control mechanism, and an air intake assembly arranged in the crystallization centrifugal drying control mechanism; the pressure-bearing heat release mechanism is used to provide a heat source and a supporting force for the wet product in the crystallization centrifugal drying control mechanism; the driving mechanism is used to provide a driving force for centrifugal granulation for the crystallization centrifugal drying control mechanism; the crystallization centrifugal drying control mechanism comprises an inner bin, a device A base is placed at the bottom of the inner bin, a gear end is installed at the top of the inner bin, a feeding piece is movably installed inside the gear end, and the feeding piece is located in the inner cavity of the inner bin, and the inner wall of the inner bin is provided with evenly distributed holes; the particle thickness adjustment mechanism includes a plurality of outer plates evenly distributed on the outside of the inner bin, five evenly distributed granulation column heads are installed on the inner side of the outer plates, and the granulation column heads are adapted to pass through the holes in the inner wall of the inner bin, so as to provide a loading mold for the wet products; the air intake assembly is used to provide an air supply channel for auxiliary drying of the wet products treated by centrifugation.

[0008] In a preferred example, the present invention can be further configured as follows: the grain thickness adjustment mechanism further includes a ring washer and a slide rail;

[0009] The inside of the ring gasket is provided with evenly distributed vertical holes, and a push rod is installed in the vertical hole, and a sliding seat is installed at the bottom end of the push rod;

[0010] An inclined frame is movably mounted on the slide seat, and the bottom end of the inclined frame is movably mounted on the outer plate;

[0011] A slide groove is provided inside the slide rail, and a return compression spring is provided at the bottom of the slide rail;

[0012] The slide seat is movably installed in the slide groove, and the top end of the return compression spring is pressed against the bottom end of the slide seat.

[0013] In a preferred example, the present invention may be further configured as follows: the air intake assembly includes a flow guide pipe;

[0014] An air pipe is installed on the pipeline at the bottom end of the guide pipe, a material guide end is installed at the top end of the guide pipe, and an anti-overflow outer cylinder is installed at the bottom of the material guide end;

[0015] An anti-overflow gap is provided between the anti-overflow outer cylinder and the guide pipe, and an air supply gap is provided between the anti-overflow outer cylinder and the bottom of the inner cavity of the base;

[0016] The top of the flow guide pipe is provided with a plurality of evenly distributed air holes, and the air holes are used to transfer the hot air flow to the anti-overflow gap and transfer it from the air supply gap to the inner cavity of the base.

[0017] In a preferred example, the present invention can be further configured as follows: the crystallization centrifugal drying control mechanism also includes a chuck, a movable cover is movably installed between the chuck and the feeding piece, and a feeding piece is arranged inside the movable cover;

[0018] The material conveying member is composed of a limiting sleeve and a material pipe.

[0019] In a preferred example, the present invention can be further configured as follows: the outer wall of the inner bin is provided with a plurality of slots evenly distributed;

[0020] An exhaust assembly is arranged in the notch at the top of the inner bin;

[0021] The exhaust component comprises a valve pipe, a tension spring is arranged in the inner cavity of the valve pipe, and a top cover is installed on the top end of the tension spring.

[0022] In a preferred example, the present invention can be further configured as follows: the pressure-bearing heat-releasing mechanism includes a cushion member arranged outside the base, an outer bin is arranged outside the cushion member, a support member is arranged at the bottom of the inner cavity of the outer bin, and the arc-shaped concave surface of the top of the support member is attached to the outer wall of the base;

[0023] Heat-conducting parts are arranged in the annular grooves of the outer bin and the supporting part, and heating resistance wires are arranged on the heat-conducting parts to provide heat for the rotating base.

[0024] In a preferred example, the present invention may be further configured as follows: the pressure-bearing heat-releasing mechanism further includes a first hydraulic component and a second hydraulic component;

[0025] A transverse beam plate is installed at the top end of the hydraulic sub-rod in the first hydraulic component, and the other end of the beam plate is installed on the clamp;

[0026] A buckle is installed at the top end of the hydraulic sub-rod in the second hydraulic component;

[0027] The ring gasket is movably installed inside the ring buckle.

[0028] In a preferred example, the present invention can be further configured as follows: the driving mechanism includes a chassis arranged on the outer bin, a motor is arranged inside the chassis, a gear at the top end of the transmission shaft inside the motor, and a chain is connected to the gear in a transmission manner;

[0029] The other end of the chain is drivingly connected to the gear end.

[0030] In a preferred example, the present invention can be further configured as follows: the surface of the outer bin is coated with a heat-insulating paint layer, and a vertically distributed first clamp and a second clamp are provided on the top of the outer side of the outer bin;

[0031] The number of the first clamp and the number of the second clamp are both two sets;

[0032] The first hydraulic component is installed in two groups of first clamps, and the second hydraulic component is installed in two groups of second clamps.

[0033] In a preferred example, the present invention can be further configured as follows: the feeding member is composed of a T-shaped elongated tube and a plug, and the bottom end of the T-shaped elongated tube is connected to the inner cavity of the base.

[0034] By adopting the above technical solution, the beneficial effects achieved by the present invention are:

[0035] 1. The present invention sets an inner bin, opens evenly distributed holes on the inner wall of the inner bin and sets movable and extendable granulation columns in the holes. After the damp products are input into the cavity formed by the inner bin and the base, the cavity separated by the feeding piece can be centrifugally dried for the damp products, and the gradually dried materials will be poured into the holes as the feeding piece rises and falls regularly, and finally form particles under the repeated squeezing of the feeding piece. Under the regulation of the granulation piece, the size of the granulation can be selectively adjusted.

[0036] 2. The present invention arranges an air intake component in the end tube at the bottom of the base. As the component continuously injects hot air flow into the base and the feeding piece cavity, as the feeding piece rises and falls regularly, the hot air flow can provide a climbing thrust for the wet product material to facilitate the continuous pouring of the material into the granulation hole. Combined with the repeated descending and squeezing of the feeding piece, the material can finally be fully compressed and formed into a suitable particle state, thereby improving the granulation efficiency of the wet product.

[0037] 3. The present invention provides a movable feeding member in the inner bin and the gear end, and provides an unobstructed and rotatable feeding member between the feeding member and the chuck. At this time, the device does not need to worry about the newly input wet products being obstructed by the reserved dry materials, thereby improving the continuous granulation operation of the wet products. BRIEF DESCRIPTION OF THE DRAWINGS

[0038] Figure 1 It is a schematic diagram of the present invention when used;

[0039] Figure 2 It is a bottom view schematic diagram of the present invention;

[0040] Figure 3 It is a schematic diagram of the pressure-bearing and heat-releasing mechanism of the present invention;

[0041] Figure 4 is a schematic diagram of the grain thickness adjustment mechanism of the present invention;

[0042] Figure 5 For the present invention Figure 4 Schematic diagram of a partial explosion;

[0043] Figure 6 For the present invention Figure 5 The enlarged schematic diagram of point A in the middle;

[0044] Figure 7 It is a schematic diagram of the crystallization centrifugal control mechanism of the present invention;

[0045] Figure 8 For the present invention Figure 7 The enlarged schematic diagram of point B in the middle;

[0046] Fig. 9 Schematic diagram of the air intake assembly of the present invention.

[0047] Reference numerals:

[0048] 100, pressure-bearing heat-releasing mechanism; 110, outer compartment; 120, cushion; 130, support; 140, heat-conducting member; 150, heating resistance wire; 160, first hydraulic member; 170, beam plate; 180, second hydraulic member; 190, buckle;

[0049] 200, driving mechanism; 210, chassis; 220, motor; 230, gear; 240, chain;

[0050] 300, crystallization centrifugal control mechanism; 310, inner chamber; 320, base; 330, slot; 340, gear end; 350, feeding piece; 360, movable cover; 370, feeding piece; 380, chuck; 390, exhaust assembly; 391, valve pipe; 392, tension spring; 393, top cover;

[0051] 400, grain thickness adjustment mechanism; 410, slide rail; 420, return compression spring; 430, slide seat; 440, push rod; 450, inclined frame; 460, outer plate; 470, granulation column head; 480, ring gasket;

[0052] 500, air inlet assembly; 510, flow guide pipe; 520, material guide end; 530, anti-overflow outer cylinder; 540, air pipe; 550, air hole. DETAILED DESCRIPTION

[0053] To make the purpose, technical solution and advantages of the present invention more clear, the present invention is further described in detail below in combination with specific implementations and with reference to the accompanying drawings. It should be noted that the embodiments of the present invention and the features in the embodiments can be combined with each other without conflict.

[0054] It is to be understood that these descriptions are exemplary only and are not intended to limit the scope of the invention.

[0055] A oxytetracycline hydrochloride wet powder granulator provided by some embodiments of the present invention will be described below in conjunction with the accompanying drawings.

[0056] Embodiment 1:

[0057] Combination Figure 1-Figure 9 As shown, the present invention provides an oxytetracycline hydrochloride wet powder granulator, comprising a pressure-bearing and heat-releasing mechanism 100, a driving mechanism 200 arranged on the pressure-bearing and heat-releasing mechanism 100, a crystallization centrifugal drying control mechanism 300 arranged in the pressure-bearing and heat-releasing mechanism 100, a particle thickness adjustment mechanism 400 arranged on the crystallization centrifugal drying control mechanism 300, and an air intake assembly 500 arranged in the crystallization centrifugal drying control mechanism 300, the pressure-bearing and heat-releasing mechanism 100 is used to provide a heat source and a supporting force for the wet product in the crystallization centrifugal drying control mechanism 300, the driving mechanism 200 is used to provide a driving force for centrifugal granulation for the crystallization centrifugal drying control mechanism 300, the crystallization centrifugal drying control mechanism 300 is used to granulate the wet product in multiple specifications, the particle thickness adjustment mechanism 400 is used to freely adjust the granulation specifications of the wet product, and the air intake assembly 500 is used to provide an air supply channel for auxiliary drying of the wet product treated by centrifugation.

[0058] The crystallization centrifugal control mechanism 300 includes an inner bin 310 and a chuck 380, a base 320 arranged at the bottom of the inner bin 310, a gear head 340 is installed at the top of the inner bin 310, a feeding piece 350 is movably installed inside the gear head 340, and the feeding piece 350 is located in the inner cavity of the inner bin 310, and the inner wall of the inner bin 310 is provided with evenly distributed holes, a movable cover 360 is movably installed between the chuck 380 and the feeding piece 350, and a feeding piece 370 is arranged inside the movable cover 360;

[0059] The material conveying member 370 is composed of a limiting sleeve and a material pipe;

[0060] The outer wall of the inner bin 310 is provided with multiple slots 330 evenly distributed;

[0061] An exhaust assembly 390 is disposed in the notch at the top of the inner bin 310;

[0062] The exhaust assembly 390 includes a valve tube 391, a tension spring 392 is disposed in the inner cavity of the valve tube 391, and a top cover 393 is installed on the top end of the tension spring 392;

[0063] The grain thickness adjustment mechanism 400 includes a plurality of outer plates 460 evenly distributed on the outer side of the inner bin 310, and five evenly distributed granulation column heads 470 are installed on the inner side of the outer plates 460, and the granulation column heads 470 are adapted to penetrate the holes on the inner wall of the inner bin 310, and are used to provide a mold for loading materials for the wet products;

[0064] The air intake assembly 500 includes a flow guide tube 510;

[0065] An air pipe 540 is installed on the pipeline at the bottom of the guide pipe 510, a material guide end 520 is installed at the top of the guide pipe 510, and an anti-overflow outer cylinder 530 is installed at the bottom of the material guide end 520;

[0066] An anti-overflow gap is provided between the anti-overflow outer cylinder 530 and the flow guide tube 510, and an air supply gap is provided between the anti-overflow outer cylinder 530 and the bottom of the inner cavity of the base 320;

[0067] The top of the flow guide tube 510 is provided with a plurality of evenly distributed air holes 550 , and the air holes 550 are used to transfer the hot air flow into the anti-overflow gap and transfer it from the air supply gap to the inner cavity of the base 320 .

[0068] Since oxytetracycline hydrochloride needs to be prepared from molds or spores, after the molds and spores are extracted with a variety of chemical agents, the obtained crude product needs to be filtered multiple times to form a damp product. However, when the damp product is processed by the existing granulating equipment, there are still certain defects. Since the specifications of the granulating molds in the existing granulating equipment are constant, the specifications after granulation cannot be effectively selectively adjusted. At the same time, the residual materials of the damp product in the granulating equipment that cannot be completely processed will also hinder the input of subsequent damp products.

[0069] The device is provided with an inner bin 310 of a constant pressure cavity, and evenly distributed holes are opened in the inner wall of the inner bin 310, and a granulation column head 470 is movably installed in the hole. When the damp product is injected along the feeding piece 370, it is transferred along the inner cavity of the feeding piece 350, and finally the damp product is stored in the cavity of the base 320, and is sealed by the bottom plug of the feeding piece 350. At this time, the damp product can be in a closed cavity. With the start-up of the motor 220, its internal transmission shaft will cooperate with the gear 230 and the chain 240 to drive the gear end 340, the inner bin 310 and the base 320. At this time, the damp product in the closed cavity can be centrifugally dried.

[0070] At the same time, the hot air flow will be transferred to the guide tube 510 through the air pipe 540, and the hot air flow can enter the gap between the guide tube 510 and the anti-overflow outer cylinder 530 from the air hole 550, and finally the hot air flow can flow upward along the bottom of the inner cavity of the base 320. With the centrifugal operation of the base 320, the damp products can climb toward the inner wall of the inner bin 310. With the upward lifting of the bottom plug of the feeding piece 350, the dried material can be repeatedly squeezed into the holes on the inner wall of the inner bin 310. With the repeated lifting and lowering of the bottom plug of the feeding piece 350, the material in the holes can be compressed until it becomes a granular state. The outer plate 460 and the granulation column head 470 extend outward, and different degrees of cavities are formed between the holes and the granulation column head 470, so that the size of the particles can be selectively adjusted.

[0071] Embodiment 2:

[0072] Combination Figure 3-Figure 7 As shown, on the basis of Example 1, the pressure-bearing heat-releasing mechanism 100 includes a first hydraulic component 160 and a second hydraulic component 180, a cushion 120 arranged outside the base 320, an outer bin 110 is arranged outside the cushion 120, a support 130 is arranged at the bottom of the inner cavity of the outer bin 110, and the arc-shaped concave surface of the top of the support 130 is attached to the outer wall of the base 320;

[0073] A heat conducting member 140 is disposed in the annular grooves of the outer bin 110 and the bracket 130 , and a heating resistor 150 is disposed on the heat conducting member 140 for providing heat to the rotating base 320 .

[0074] Preferably, a power cord is provided on the connector of the heating resistor wire 150. When the power cord is connected to a power source, the heating resistor wire 150 can continuously release heat energy, and eventually the heat energy can be released outward from the heat conductor 140. The released heat energy can provide auxiliary heat energy to the outer wall of the base 320. Finally, when the base 320 in a rotating state centrifugally drys the damp product, the heat energy can be used to accelerate the drying speed of the material.

[0075] A transverse beam plate 170 is installed at the top end of the hydraulic sub-rod in the first hydraulic component 160, and the other end of the beam plate 170 is installed on the clamp 380;

[0076] A ring buckle 190 is installed at the top end of the hydraulic sub-rod in the second hydraulic component 180;

[0077] The ring washer 480 is movably installed inside the ring buckle 190 .

[0078] Preferably, the ring buckle 190 is used to provide a support platform for the ring gasket 480 to rotate without obstruction. When the gear end 340 drives the inner bin 310 and the base 320 to rotate, the particle thickness adjustment mechanism 400 as a whole can rotate in coordination with the inner bin 310. In order to meet the free lifting and lowering of the ring gasket 480, the ring buckle 190 can provide stable kinetic energy for the lifting and lowering of the ring gasket 480.

[0079] The surface of the outer bin 110 is coated with a heat-insulating paint layer, and a first clamp and a second clamp distributed vertically are provided on the top of the outer side of the outer bin 110;

[0080] The number of the first clamp and the number of the second clamp are both two sets;

[0081] The first hydraulic component 160 is installed in two sets of first clamps, and the second hydraulic component 180 is installed in two sets of second clamps.

[0082] Preferably, the inner diameter of the first clamp is larger than the inner diameter of the second clamp. When the two groups of first clamps fix the first hydraulic component 160, the hydraulic sub-rod in the first hydraulic component 160 cooperates with the lifting and lowering of the beam plate 170 to drive the chuck 380 and the feeding component 350 to rise and fall smoothly, and the movable cover 360 movably installed between the chuck 380 and the feeding component 350 will not hinder the lifting and lowering of the feeding component 350, and can provide a stable feeding platform for the feed component 370.

[0083] Embodiment 3:

[0084] Combination Figure 4 and Figure 5 As shown, based on the embodiment 1, the particle thickness adjustment mechanism 400 further includes a ring washer 480 and a slide rail 410;

[0085] The ring gasket 480 is provided with uniformly distributed vertical holes inside, and a push rod 440 is installed in the vertical hole, and a slide seat 430 is installed at the bottom end of the push rod 440;

[0086] An inclined frame 450 is movably mounted on the slide seat 430 , and the bottom end of the inclined frame 450 is movably mounted on the outer plate 460 .

[0087] Preferably, in the initial state, the return compression spring 420 will support the slide 430 upward. At this time, the slide 430 is located in the middle of the internal slide groove of the slide rail 410, and the outer plate 460 pulled by the inclined frame 450 is attached to the outer wall of the inner warehouse 310. At this time, the inner end of the granulation column head 470 is flush with the inner end of the inner wall hole of the inner warehouse 310. At this time, the bottom plug of the feeding piece 350 is located at the bottom of the inner wall hole of the inner warehouse 310, so as to provide a dry environment for damp products.

[0088] A slide groove is provided inside the slide rail 410, and a return compression spring 420 is provided at the bottom of the slide rail;

[0089] The slide seat 430 is movably installed in the slide groove, and the top end of the return compression spring 420 is pressed against the bottom end of the slide seat 430 .

[0090] Preferably, when the ring gasket 480 is pressurized and lifted smoothly, the multiple push rods 440 will be pressurized and lifted synchronously. At this time, the multiple slides 430 can apply pressure to the multiple inclined frames 450 at the same time. At this time, the multiple granulation column heads 470 and the multiple holes can synchronously form a unified mold hole, thereby facilitating the rapid granulation operation of the material.

[0091] Embodiment 4:

[0092] Combination Figure 3-Figure 9 As shown, based on the embodiment 1, the driving mechanism 200 includes a chassis 210 disposed on the outer bin 110, a motor 220 is disposed inside the chassis 210, a gear 230 at the top of the transmission shaft in the motor 220, and a chain 240 is connected to the gear 230;

[0093] The other end of the chain 240 is drivingly connected to the gear end 340;

[0094] The feeding member 350 is composed of a T-shaped elongated tube and a plug, and the bottom end of the T-shaped elongated tube is connected to the inner cavity of the base 320 .

[0095] Preferably, when the motor 220 is started, the transmission shaft in the motor 220 will cooperate with the gear 230 to drive the chain 240 to rotate, and the other end of the chain 240 will drive the gear end 340. At this time, the gear end 340, the inner bin 310 and the base 320 that form a fixed structure can provide a centrifugal drying container for the damp products, and cooperate with the air intake assembly 500 to introduce hot air flow and the heating resistor wire 150 to radiate heat energy, so that the damp products in the centrifugal state can be efficiently dried.

[0096] The working principle and use process of the present invention are as follows: oxytetracycline hydrochloride is mainly prepared by slant spores or soil streptomyces, the cultured spores are made into a suspension and then fermented, and finally the fermentation liquid is pretreated and the pH is adjusted with an alkalizing agent in an acidic decolorizing liquid until oxytetracycline is directly precipitated and crystallized from the filtrate, and then yellow blood salt-zinc sulfate is used as a purifying agent to remove high molecular impurities such as proteins, and the washed filtrate can be further crystallized to obtain a tide product;

[0097] After the wet product is input from the feeding member 370, it will eventually enter the inner cavity of the base 320 along the inner cavity of the feeding member 350. At this time, the air intake assembly 500 is installed in the conduit at the bottom of the base 320, and then the first hydraulic member 160 is operated until its internal hydraulic sub-rod drives the beam plate 170 and the clamp 380 to fall downward. At this time, the feeding member 350 movably clamped by the movable cover 360 will descend toward the inner cavity of the inner bin 310 until the bottom plug of the feeding member 350 is located at the bottom of the hole on the inner wall of the inner bin 310. At this time, the wet product located in the inner cavity of the base 320 can be sealed;

[0098] Then the motor 220 is started, and the transmission shaft in the motor 220 cooperates with the gear 230 to drive the chain 240, and the other end of the chain 240 drives the gear end 340. At this time, the gear end 340, the inner bin 310 and the base 320 can be in a high-speed rotation state, and the sealed damp products can be centrifugally processed;

[0099] With the centrifugal treatment of the damp products, the air pipe 540 conveys the hot air flow toward the inner cavity of the flow guide pipe 510, and the hot air flow transferred along the air hole 550 can be released from the gap between the flow guide pipe 510 and the overflow prevention outer cylinder 530 toward the inner cavity of the base 320. At this time, the hot air flow rising along the bottom of the inner cavity of the base 320 can dry the damp products in the centrifugal state, and the overloaded air pressure will rise along the gap between the plug at the bottom of the feeding piece 350 and the inner wall of the inner bin 310, and finally squeeze the top cover 393 upward, and finally the overloaded air pressure can be released outward from the gap between the valve tube 391 and the top cover 393.

[0100] At the same time, after the exposed wire of the heating resistor 150 is energized, the heating resistor 150 will release heat and radiate outward from the heat-conducting member 140. At this time, the gap formed by the base 320, the outer bin 110 and the support 130 can facilitate the rapid transfer of heat energy, and finally the heat energy will radiate to the base 320 over a wide area. As the damp product gradually dries, the second hydraulic member 180 can be operated. At this time, the hydraulic sub-rod in the second hydraulic member 180 will drive the ring buckle 190 and the multiple propulsion rods 440 to descend, and the slide seat 430 will drive the inclined frame 45 0 and the outer plate 460 extend outwards, and at this time, the multiple granulation column heads 470 installed in the outer plate 460 will extend outwards from the holes in the inner wall of the inner bin 310, and at this time, the granulation column heads 470 and the holes in the inner wall of the inner bin 310 will form a groove, and then the first hydraulic component 160 will be operated again until its internal hydraulic sub-rod cooperates with the beam plate 170 to carry the feeding component 350 to lift upwards, until the holes in the inner wall of the inner bin 310 are completely exposed in the cavity formed by the base 320 and the inner bin 310, and at this time, the centrifugally thrown materials will splash into the groove;

[0101] According to the above-mentioned operation method, the regular lifting and lowering of the feeding member 350 is continuously controlled until the material is extruded and granulated in the groove. The above-mentioned outer plate 460 carries the granulation column head 470 to reset, so that the granulated oxytetracycline hydrochloride particles can be squeezed out. As the air intake component 500 is pulled out from the base 320, the granulated oxytetracycline hydrochloride can be quickly discharged.

[0102] Although the embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the claims and their equivalents.

Claims

1. A oxytetracycline hydrochloride wet powder granulator, comprising a pressure-bearing and heat-releasing mechanism (100), characterized in that: It also includes a driving mechanism (200) arranged on the pressure-bearing and heat-releasing mechanism (100), a crystallization centrifugal drying control mechanism (300) arranged in the pressure-bearing and heat-releasing mechanism (100), a particle thickness adjustment mechanism (400) arranged on the crystallization centrifugal drying control mechanism (300), and an air intake assembly (500) arranged in the crystallization centrifugal drying control mechanism (300); The pressure-bearing heat-releasing mechanism (100) is used to provide a heat source and a supporting force for the wet product in the crystallization centrifugal drying control mechanism (300); The driving mechanism (200) is used to provide a driving force for centrifugal granulation for the crystallization centrifugal drying control mechanism (300); The crystallization centrifugal control mechanism (300) comprises an inner bin (310), a base (320) arranged at the bottom of the inner bin (310), a gear head (340) is installed at the top of the inner bin (310), a feeding piece (350) is movably installed inside the gear head (340), and the feeding piece (350) is located in the inner cavity of the inner bin (310), and the inner wall of the inner bin (310) is provided with evenly distributed holes; The particle thickness adjustment mechanism (400) comprises a plurality of outer plates (460) evenly distributed on the outside of the inner bin (310), and five evenly distributed granulation column heads (470) are installed on the inner side of the outer plates (460), and the granulation column heads (470) are adapted to penetrate through the holes on the inner wall of the inner bin (310), so as to provide a loading mold for the wet product; The air intake assembly (500) is used to provide an air supply channel for auxiliary drying of wet products subjected to centrifugal treatment.

2. The oxytetracycline hydrochloride wet powder granulator according to claim 1, characterized in that: The particle thickness adjustment mechanism (400) further includes a ring washer (480) and a slide rail (410); The ring gasket (480) is provided with evenly distributed vertical holes inside, and a push rod (440) is installed in the vertical hole, and a sliding seat (430) is installed at the bottom end of the push rod (440); An inclined frame (450) is movably mounted on the slide seat (430), and the bottom end of the inclined frame (450) is movably mounted on the outer plate (460); The slide rail (410) has a slide groove inside, and a return compression spring (420) is provided at the bottom of the slide rail; The slide seat (430) is movably installed in the slide groove, and the top end of the return compression spring (420) is pressed against the bottom end of the slide seat (430).

3. The oxytetracycline hydrochloride wet powder granulator according to claim 1, characterized in that: The air intake assembly (500) comprises a flow guide pipe (510); An air pipe (540) is installed on the pipeline at the bottom end of the flow guide pipe (510), a material guide end head (520) is installed at the top end of the flow guide pipe (510), and an anti-overflow outer cylinder (530) is installed at the bottom of the material guide end head (520); An anti-overflow gap is provided between the anti-overflow outer cylinder (530) and the flow guide tube (510), and an air supply gap is provided between the anti-overflow outer cylinder (530) and the bottom of the inner cavity of the base (320); The top of the flow guide tube (510) is provided with a plurality of evenly distributed air holes (550), and the air holes (550) are used to transfer the hot air flow into the anti-overflow gap and transfer it from the air supply gap to the inner cavity of the base (320).

4. The oxytetracycline hydrochloride wet powder granulator according to claim 1, characterized in that: The crystallization centrifugal control mechanism (300) further comprises a chuck (380), a movable cover (360) is movably installed between the chuck (380) and the feeding member (350), and a feeding member (370) is arranged inside the movable cover (360); The material conveying member (370) is composed of a limiting sleeve and a material pipe.

5. The oxytetracycline hydrochloride wet powder granulator according to claim 1, characterized in that: The outer wall of the inner bin (310) is provided with a plurality of slots (330) evenly distributed; An exhaust assembly (390) is disposed in the notch at the top of the inner bin (310); The exhaust assembly (390) comprises a valve tube (391), a tension spring (392) is arranged in the inner cavity of the valve tube (391), and a top cover (393) is installed at the top end of the tension spring (392).

6. The oxytetracycline hydrochloride wet powder granulator according to claim 1, characterized in that: The pressure-bearing heat-releasing mechanism (100) comprises a cushion (120) arranged outside the base (320), an outer bin (110) is arranged outside the cushion (120), a support (130) is arranged at the bottom of the inner cavity of the outer bin (110), and the arc-shaped concave surface of the top of the support (130) is attached to the outer wall of the base (320); A heat conducting member (140) is arranged in the annular grooves of the outer bin (110) and the supporting member (130), and a heating resistance wire (150) is arranged on the heat conducting member (140) for providing heat to the rotating base (320).

7. The oxytetracycline hydrochloride wet powder granulator according to claim 2, characterized in that: The pressure-bearing and heat-releasing mechanism (100) further comprises a first hydraulic component (160) and a second hydraulic component (180); A transverse beam plate (170) is installed at the top end of the hydraulic sub-rod in the first hydraulic component (160), and the other end of the beam plate (170) is installed on the clamp (380); A buckle (190) is installed at the top end of the hydraulic sub-rod in the second hydraulic component (180); The ring washer (480) is movably mounted inside the ring buckle (190).

8. The oxytetracycline hydrochloride wet powder granulator according to claim 1, characterized in that: The driving mechanism (200) comprises a chassis (210) arranged on the outer bin (110), a motor (220) being arranged inside the chassis (210), a gear (230) at the top end of a transmission shaft inside the motor (220), and a chain (240) being transmission-connected to the gear (230); The other end of the chain (240) is drivingly connected to the gear end (340).

9. The oxytetracycline hydrochloride wet powder granulator according to claim 7, characterized in that: The surface of the outer bin (110) is coated with a heat-insulating paint layer, and a first clamp and a second clamp distributed vertically are arranged on the top of the outer side of the outer bin (110); The number of the first clamp and the number of the second clamp are both two sets; The first hydraulic component (160) is installed in two groups of first clamps, and the second hydraulic component (180) is installed in two groups of second clamps.

10. The oxytetracycline hydrochloride wet powder granulator according to claim 1, characterized in that: The feeding member (350) is composed of a T-shaped elongated conduit and a plug, and the bottom end of the T-shaped elongated conduit is connected to the inner cavity of the base (320).

Images