High-flux automatic nucleic acid extractor

By designing a high-throughput automatic nucleic acid extractor and using rotary mixing components and heating components, the problems of low nucleic acid extraction efficiency and high noise in the prior art are solved, and efficient and low-noise nucleic acid extraction effect is achieved.

CN119432560APending Publication Date: 2025-02-14雷奥顶峰(苏州)生命科学有限责任公司
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Patent Information

Application Number
CN202411586939.0
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-11-08
Publication Date
2025-02-14

AI Technical Summary

Technical Problem

The flux and efficiency of existing nucleic acid extraction equipment are low, and there are problems such as high noise and bubble generation when oscillating up and down the magnetic beads or pipetting and mixing.

Method used

A high-throughput automatic nucleic acid extractor is designed, using rotary mixing components, heating components, lifting components and moving components, and mixing them through rotation to avoid vibration and blowing and improve efficiency.

Benefits of technology

It realizes efficient nucleic acid extraction, avoids problems such as high noise and bubble generation, and improves overall work efficiency.

✦ Generated by Eureka AI based on patent content.

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Abstract

The embodiment of the invention provides a high-flux automatic nucleic acid extraction instrument. The high-flux automatic nucleic acid extraction instrument comprises a rotary uniform mixing assembly, a heating assembly, a lifting assembly and a moving assembly, the moving assembly comprises a moving part and a bottom plate. The heating assembly is fixed above the bottom plate and is used for heating the to-be-extracted product. The moving part is arranged above the bottom plate and located on the side face of the heating assembly. The lifting assembly is connected with the moving component and used for horizontally moving on one side of the heating assembly along with the moving component. The rotary uniform mixing assembly is fixedly connected with the lifting assembly and is used for vertically moving along with the lifting assembly. According to the device, the to-be-extracted product is uniformly mixed in a rotating manner, so that the problems of high noise, bubble generation and the like caused by a vibration or blowing and beating uniform mixing manner are avoided. Meanwhile, automatic movement of the rotary uniform mixing assembly is achieved through the lifting assembly and the moving component, and the overall working efficiency is improved.
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Description

Technical Field

[0001] The present invention relates to the field of experimental equipment, and in particular to a high-throughput automatic nucleic acid extraction instrument. Background Art

[0002] Nucleic acid extraction equipment is widely used in chemical industry, food, medicine, microbial molecules, molecular biology and other fields. Most of the existing nucleic acid extraction equipment is designed for 8-channel extraction, and the throughput and efficiency of single nucleic acid extraction are relatively low. At the same time, most of the related technologies use magnetic beads to shake up and down to mix or pipette to blow on the magnetic beads to mix, and both methods have certain disadvantages. Among them, the vibration and noise of the magnetic beads shaking up and down to mix are too large, and the pipette blowing on the magnetic beads to mix is ​​prone to bubbles, which affects the final extraction effect. Summary of the invention

[0003] The present invention aims to solve the deficiencies of the prior art and to improve the efficiency of the nucleic acid extraction process and the effect of the extracted nucleic acid.

[0004] In one aspect, the present disclosure provides a high-throughput automatic nucleic acid extraction instrument, comprising:

[0005] Rotating mixing component, heating component, lifting component and moving component;

[0006] The mobile assembly includes a mobile part and a base plate;

[0007] The heating component is fixed above the bottom plate and is used to heat the extract;

[0008] The moving component is arranged above the bottom plate and located on the side of the heating assembly;

[0009] The lifting assembly is connected to the moving component and is used to move horizontally along with the moving component on one side of the heating assembly;

[0010] The rotating mixing component is fixedly connected to the lifting component and is used for vertically moving with the lifting component.

[0011] In a possible implementation, the rotating mixing assembly includes a first support plate, a first magnetic rod set, a second magnetic rod set and a third magnetic rod set, and each of the magnetic rod sets includes a preset number of magnetic rod sets that are fixedly spaced and arranged in a straight line;

[0012] The first magnetic rod set, the second magnetic rod set and the third magnetic rod set are positioned in parallel and are respectively arranged on the left side, the middle and the right side of the first support plate, wherein each magnetic rod set is located on the bottom surface of the first support plate and is perpendicular to the bottom surface.

[0013] In a possible implementation, the rotating mixing component further includes a first driving motor, a first transmission component, and a second transmission component;

[0014] The first driving motor is fixed to one side of the first supporting plate and is located between the first magnetic bar set and the second magnetic bar set;

[0015] The first transmission assembly is connected to the first drive motor, the first magnetic rod set and the second magnetic rod set, and is used to drive each of the magnetic rod sets in the first magnetic rod set and the second magnetic rod set to rotate;

[0016] The second rotating assembly is connected to the second magnetic bar set and the third magnetic bar set, and is used to drive the third magnetic bar set to rotate when the second magnetic bar set rotates.

[0017] In a possible implementation, the lifting assembly includes a second driving motor and a first driven module;

[0018] The second driving motor is used to drive the first driven module to move vertically;

[0019] The first driven module is fixedly connected to the first supporting plate.

[0020] In a possible implementation, the first driven module includes a lead screw and a rotating nut;

[0021] The output shaft of the second drive motor is fixedly connected to the lead screw;

[0022] The inner side of the rotating nut is threadedly connected to the lead screw, and the outer side is connected to the rotating mixing component.

[0023] In a possible implementation, the lifting assembly further includes a vertical support arranged in a vertical direction;

[0024] The second driving motor is fixedly connected to the vertical support.

[0025] In a possible implementation, the moving component includes a third driving motor and a second driven module;

[0026] The third driving motor is fixed to the base plate, and the second driven module is fixedly connected to the lifting assembly.

[0027] In a possible implementation, the second driven module includes a driving wheel, a driven wheel and a synchronous belt;

[0028] The driving wheel and the driven wheel are connected via the synchronous belt;

[0029] The rotating shaft of the driving wheel is fixedly connected to the output shaft of the third driving motor;

[0030] The synchronous belt is fixedly connected to the lifting assembly.

[0031] In a possible implementation, the heating assembly includes a second support plate and at least one heating seat;

[0032] The heating seat is fixed in parallel above the second support plate at a fixed interval, and is used for placing the extract to be extracted and heating the extract to be extracted.

[0033] In a possible implementation, the heating assembly further includes a control system corresponding to each of the heating seats;

[0034] The control system is arranged at a position below the second supporting plate corresponding to the heating seat.

[0035] In the disclosed embodiment, the high-throughput automatic nucleic acid extractor mixes the extract in a rotating manner, thereby avoiding the problems of high noise and bubbles caused by oscillation or blowing mixing. At the same time, the automatic movement of the rotating mixing component is achieved through the lifting component and the moving parts, thereby improving the overall work efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0036] This specification describes the complete and instructive disclosure of the present application, including its best mode of implementation, for those skilled in the art. This specification refers to the accompanying drawings, in which:

[0037] Figure 1 This is one of the structural schematic diagrams of a high-throughput automatic nucleic acid extraction instrument provided in an embodiment of the present disclosure;

[0038] Figure 2 One of the structural schematic diagrams of a rotating mixing component provided in an embodiment of the present disclosure;

[0039] Figure 3 The second structural schematic diagram of a rotating mixing component provided in an embodiment of the present disclosure;

[0040] Figure 4 A structural schematic diagram of a lifting assembly provided in an embodiment of the present disclosure;

[0041] Figure 5 The second structural schematic diagram of a high-throughput automatic nucleic acid extraction instrument provided in an embodiment of the present disclosure.

[0042] Figure Number:

[0043] Reference numerals:

[0044] 1. Rotating and mixing assembly; 11. Magnetic rod assembly; 111. Fixed plate; 112. Magnetic rod; 12. Rotating assembly; 121. First drive motor; 122. First gear; 123. Second gear; 124. Third gear; 125. Magnetic rod sleeve; 126. First support plate; 2. Lifting assembly; 21. Lifting module; 211. Second drive motor; 212 Lead screw; 213. Rotating nut; 214. Connecting frame; 22. Limiting Module; 221, fourth drive motor; 222, limit screw; 223, limit nut; 224, limit frame; 23, slideway assembly; 231, slideway; 232, slider; 24, vertical bracket; 3, moving part; 31, third drive motor; 32, driving wheel; 33, driven wheel; 34, synchronous belt; 4, heating assembly; 41, heating seat; 42, control system; 43, second support plate; 5, bottom plate; 6, to be extracted. DETAILED DESCRIPTION

[0045] Now with reference to the embodiments of the present application in detail, one or more examples of the embodiments of the present application are illustrated in the drawings. Each example is provided to explain the present application, but not to limit the present application. In fact, it will be clear to those skilled in the art that various modifications and changes can be made in the present application without departing from the scope or spirit of the present application. For example, the features described or described as a part of an embodiment can be used together with another embodiment to produce another embodiment. As used in this specification, the terms "first", "second", etc. are used interchangeably to distinguish one component from another component without intending to indicate the position or importance of each component. As used in the specification, unless the context clearly indicates otherwise, the terms "one", "an", "the", and "said" are intended to indicate that there are one or more elements. The terms "include", "include" and "have" are intended to be inclusive, and mean that there may be other elements in addition to the listed elements.

[0046] Now referring to the drawings, in which the same numerals represent the same elements throughout the drawings, the present disclosure will be further explained below in conjunction with specific embodiments.

[0047] Figure 1 This is one of the structural schematic diagrams of a high-throughput automatic nucleic acid extraction instrument provided in the embodiment of the present disclosure. Figure 1 As shown, the high-throughput automatic nucleic acid extractor of the embodiment of the present disclosure includes a rotating mixing component 1, a heating component 4, a lifting component 2 and a moving component. The moving component includes a moving part 3 and a bottom plate 5.

[0048] Optionally, the heating assembly 4 is fixed above the bottom plate 5, and is used to place the extract 6 to be extracted and heat the extract 6. The extract 6 can be placed in a container of a preset shape, which can be a rectangular container, and at least one row of spaced slots is provided above the container, and multiple slots in each group of slots are arranged in a straight line, and the distance between every two adjacent slots is the same. Further, the number of slots in each group can be preset.

[0049] In a possible implementation, the heating assembly 4 includes a second support plate 43 and at least one heating seat 41. The heating seat 41 is fixedly installed above the second support plate 43 in parallel at a fixed interval, and is used to place the extract 6 to be extracted and heat the extract 6 to be extracted, and plays a certain fixing role. Optionally, the heating assembly 4 also includes a control system 42 corresponding to each heating seat 41, and the control system 42 is arranged at a position corresponding to the heating seat 41 below the second support plate 43. During the operation of the heating assembly 4, the heating seat 41 on which the extract 6 to be extracted is placed heats the extract 6 to be extracted above it. During the entire heating process, the corresponding control system 42 can be used to monitor and adjust the temperature of the heating seat.

[0050] Based on this structural setting, the embodiment of the present disclosure can achieve accurate temperature control heating of the extract 6. At the same time, the heating seat 41 can also be set as a structure with a fixed protrusion on the surface, which is used to fix the container containing the extract 6 placed thereon, so as to prevent the container from being displaced during the heating and rotating mixing process of the extract 6, thereby affecting the extraction process.

[0051] Further, the moving part 3 in the moving assembly is arranged above the bottom plate 5 and is located on one side of the heating assembly 4. The lifting assembly 2 is connected to the moving part 3, and is used to move horizontally on one side of the heating assembly 4 along with the moving part 3 during the operation of the moving part 3. The rotating mixing assembly 1 is fixedly connected to the lifting assembly 2, and is used to move vertically along with the lifting assembly 2. That is to say, during the operation, the rotating mixing assembly 1 can move vertically up and down along with the lifting assembly 2, and move vertically forward and backward along with the moving part 3. Optionally, the rotating mixing assembly 1 is located opposite to the heating assembly 4, and is used to mix the extract 6 heated on the heating assembly 4 by rotating.

[0052] Based on the above structural features, the disclosed embodiment can mix the extract in a rotating manner during the operation of the high-throughput automatic nucleic acid extractor, avoiding the problems of high noise and bubbles caused by oscillation or blowing mixing. At the same time, the lifting component 2 and the moving part 3 can also realize the automatic movement of the rotating mixing component 1 in the horizontal and vertical directions, thereby improving the overall work efficiency.

[0053] Figure 2 This is one of the structural schematic diagrams of a rotating mixing component provided in an embodiment of the present disclosure. Figure 2 As shown, the rotating mixing component 1 of the embodiment of the present disclosure also includes a rotating component 12, which includes a first support plate 126, a first magnetic rod set, a second magnetic rod set and a third magnetic rod set, and each magnetic rod set includes a preset number of magnetic rod sets 125 that are fixedly spaced and arranged in a straight line. Optionally, the number of magnetic rod sets 125 included in each magnetic rod set can be the same as the number of storage slots included in each group of storage slots in the container for placing the extract 6. Generally speaking, the number of magnetic rod sets 125 included in each group of magnetic rod sets can be 8, and each magnetic rod set 125 is used to accommodate a magnetic rod 112.

[0054] Among them, the first magnetic rod set, the second magnetic rod set and the third magnetic rod set are located in parallel and are respectively arranged on the left, middle and right sides of the first support plate 126, and each magnetic rod set 125 is located on the bottom surface of the first support plate 126 and is perpendicular to the bottom surface. Optionally, the position of each magnetic rod set and the setting position of the magnetic rod set 125 included therein can be determined according to the position of the storage slot in the container where the extract 6 is placed, so as to ensure that each magnetic rod set 125 in the first magnetic rod set, the second magnetic rod set and the third magnetic rod set can be inserted into the corresponding storage slot to rotate and mix the extract 6 during the working process of the high-throughput automatic nucleic acid extractor. Optionally, the rotation mixing method in the embodiment of the present disclosure can be to rotate the magnetic rod 112 in the magnetic rod set 125 to mix the extract 6.

[0055] Furthermore, the rotating assembly 12 of the rotating mixing assembly 1 also includes a first drive motor 121, a first transmission assembly and a second transmission assembly. Among them, the first drive motor 121 is fixed to one side of the first support plate 126 and is located between the first magnetic rod set and the second magnetic rod set. Optionally, the first support plate 126 is an L-shaped plate structure with a bottom surface size larger than the side surface, and the first drive motor 121 can be installed on the side of the first support plate 126. The first transmission assembly is connected to the first drive motor 121, the first magnetic rod set and the second magnetic rod set, and is used to drive each magnetic rod set 125 in the first magnetic rod set and the second magnetic rod set to rotate. The second rotating assembly is connected to the second magnetic rod set and the third magnetic rod set, and is used to drive the third magnetic rod set to rotate when the second magnetic rod set rotates.

[0056] In a possible implementation, the first transmission assembly and the second transmission assembly may jointly include two primary gears 122, four secondary gears 123, and a plurality of tertiary gears 124 equal in number to all the magnetic rod sleeves 125. The above-mentioned plurality of gears are all arranged on the surface of the first support plate 126, and the plurality of tertiary gears 124 are respectively fixedly connected to the magnetic rods 112 in each magnetic rod sleeve 125, and each magnetic rod sleeve 125 is arranged at the center of a corresponding tertiary gear 124, and the plurality of tertiary gears 124 corresponding to a magnetic rod sleeve group are arranged in a row in sequence and mesh with each other. Among them, the first transmission assembly and the second transmission assembly include the same number of primary gears 122, secondary gears 123, and tertiary gears 124. Exemplarily, in the case where eight magnetic rod sleeves 125 are included in each magnetic rod sleeve group, the first transmission assembly includes twelve magnetic rod sleeves 125 corresponding to all the magnetic rod sleeves 125 in the first magnetic rod sleeve group and half of the magnetic rod sleeves 125 in the second magnetic rod sleeve group. The second transmission assembly includes twelve magnetic rod sets 125 corresponding to all the magnetic rod sets 125 in the third magnetic rod set and half of the magnetic rod sets 125 in the second magnetic rod set.

[0057] Optionally, the output shaft of the first drive motor 121 is fixedly connected to the primary gear 122 in the first transmission assembly, and the two secondary gears 123 in the first transmission assembly are arranged on both sides of the primary gear 122, and are both meshed with the primary gear 122. One of the secondary gears 123 in the first transmission assembly is respectively meshed with one of the three-stage gears 123 in a row corresponding to the first magnetic rod set, and the other secondary gear 123 is meshed with one of the three-stage gears 123 in a row corresponding to the second magnetic rod set. The two secondary gears 123 in the second transmission assembly are arranged on both sides of the primary gear 122, and are both meshed with the primary gear 122. One of the secondary gears 123 in the second transmission assembly is respectively meshed with one of the three-stage gears 123 in a row corresponding to the second magnetic rod set, and the other secondary gear 123 is meshed with one of the three-stage gears 123 in a row corresponding to the third magnetic rod set.

[0058] In order to make the structure of the rotating assembly 12 simple and orderly, the structure of the rotating assembly 12 is symmetrical. The first transmission assembly and the second transmission assembly are further formed into a symmetrical structure as a whole. That is to say, each primary gear 122 is meshed with the secondary gear 123 at the same position, and each secondary gear 123 is meshed with the tertiary gear 124 at the same position in each row of tertiary gears 124. When the first drive motor 121 is started, the first primary gear 122 connected to the output shaft of the first drive motor 121 is driven to rotate, and then each tertiary gear 124 in the three rows of tertiary gears 124 drives the corresponding magnetic rod 112 in the magnetic rod sleeve 125 to rotate through the meshing of the primary gear 122, the secondary gear 123 and the tertiary gear 124.

[0059] Figure 3This is a second structural diagram of a rotating mixing component provided in an embodiment of the present disclosure. Figure 3 As shown, the rotating mixing component 1 of the embodiment of the present disclosure may also include a magnetic bar assembly 11. The magnetic bar assembly 11 includes a fixed plate 111 and a magnetic bar 112. The fixed plate 111 is arranged parallel to the first support plate 126, and a plurality of magnetic bar mounting holes are provided on the surface thereof, which are opposite to the positions of each magnetic bar sleeve 125 in the rotating component 12. The number of magnetic bars 112 matches the number of magnetic bar sleeves 125, and the magnetic bars 112 are installed in the magnetic bar mounting holes in the magnetic bar assembly 11. In the assembled rotating mixing component 1, one end of each magnetic bar 112 is located in the corresponding magnetic bar sleeve 125. During the operation of the magnetic bar sleeve group, the magnetic bar 112 in each magnetic bar sleeve 125 rotates alone or together with the magnetic bar sleeve 125.

[0060] Based on the above structural features, the disclosed embodiment can mix the extract in a rotating manner during the operation of the high-throughput automatic nucleic acid extractor, avoiding the problems of high noise and bubble generation caused by oscillation or blowing mixing. At the same time, the mixing process can be precisely controlled by controlling the first drive motor 121 to adjust the rotation speed, thereby improving the efficiency of the mixing process and the quality of the finished product.

[0061] Figure 4 This is a schematic diagram of the structure of a lifting assembly provided by an embodiment of the present disclosure. Figure 4 As shown, the lifting assembly 2 includes a lifting module 21. Optionally, the lifting module 21 includes a second drive motor 211 and a first driven module. The output shaft of the second drive motor 211 is connected to the first driven module, and is used to drive the first driven module to move up and down in the vertical direction. The first driven module is fixedly connected to the first support plate 126 in the rotating and mixing assembly 1, and can drive the rotating and mixing assembly 1 to move up and down in the vertical direction during the vertical movement.

[0062] Optionally, the first driven module may include a lead screw 212 and a rotating nut 213, and the output shaft of the second drive motor 211 may be fixedly connected to the lead screw 212, and the lead screw 212 may rotate along with the output shaft of the second drive motor 211 when the second drive motor 211 is working. The inner side of the rotating nut 213 is threadedly connected to the lead screw 212, and the outer side is connected to the rotating mixing component 1. Among them, the rotating nut 213 and the rotating mixing component 1 may be connected through a connecting member 214, the first support plate 126 of the rotating mixing component 1 is fixedly connected to the connecting member 214, and the connecting member 214 is connected to the rotating nut 213, and the connection method is that the relative position of the rotating nut 213 and the connecting member 214 is fixed, and the rotating nut 213 can be rotated inside the connecting member 214. For example, a limiting groove whose size matches the rotating nut 213 can be set inside the connecting member 214, and the rotating nut 213 is placed in the limiting groove. During the operation of the second drive motor 211, the lead screw 212 can rotate along with the output shaft of the second drive motor 211, and then the rotating nut 213 moves up and down in the vertical direction on the lead screw 212, and drives the rotating mixing component 1 to move up and down in the vertical direction through the connecting member 214. Furthermore, the lifting component 2 also includes a vertical bracket 24 arranged in the vertical direction, and the second drive motor 211 can be fixedly connected to the vertical bracket.

[0063] Furthermore, in order to ensure the stability of the first driven module during the up and down movement, the lifting assembly 2 of the embodiment of the present disclosure may further include a slide assembly 23, which is used to further limit the movement trajectory of the first driven module. Optionally, the slide assembly 23 includes a slide 231 and a slider 232, the slide 231 is vertically fixed on the vertical bracket 24, and the slider 232 is slidably connected to the slide 231 to slide up and down on the slide 231. The slider 232 is connected to the connecting member 214 to ensure the stability of the movement trajectory of the connecting member 214.

[0064] In a possible implementation, the lifting assembly 2 of the disclosed embodiment may further include a limit module 22 for limiting the highest rising position of the rotating and mixing assembly 1, that is, the moving range. The limit module 22 may include a fourth drive motor 221, a limit screw 222, a limit nut 223 and a limit frame 224. Among them, the output shaft of the fourth drive motor 221 is fixedly connected to the limit screw 222, the inner side of the limit nut 223 is threadedly connected to the limit screw 222, and the outer side is connected to the limit frame 224. This structure and connection method are similar to those of the first driven module, and will not be repeated here. The limit frame 224 is always located above the connecting member 214 and the rotating and mixing assembly 1. During the operation of the fourth drive motor 221, the limit screw 222 can rotate with the output shaft of the fourth drive motor 221, and then the limit nut 223 moves up and down in the vertical direction on the limit screw 222, and drives the limit frame 224 to move up and down. In order to further ensure the stability of the moving track of the limiting frame 224 , the limiting frame 224 can also be fixedly connected to the slider 232 on the slideway 231 .

[0065] Figure 5 The second structural diagram of a high-throughput automatic nucleic acid extraction instrument provided by the embodiment of the present disclosure. Figure 5 As shown, in the high-throughput automatic nucleic acid extractor of the embodiment of the present disclosure, the moving component 3 includes a third drive motor 31 and a second driven module. The second driven module is fixedly connected to the lifting assembly 2, and the third drive motor 31 is fixedly connected to the bottom plate 5. During the operation of the third drive motor 31, the second driven module can drive the lifting assembly 2 to move in the horizontal direction.

[0066] Optionally, the second driven module includes a driving wheel 32, a driven wheel 33 and a synchronous belt 34, and the driving wheel 32 is connected to the driven wheel 33 through the synchronous belt 34. The center of the driving wheel 32 is fixedly connected to the output shaft of the third drive motor 31. For example, the central axis of the driving wheel 32 can be fixedly connected to the output shaft of the third drive motor 31, or the output shaft of the third drive motor 31 can be directly fixed to the center of the driving wheel 32. The synchronous belt 34 is fixedly connected to the lifting component 2. Based on the above structure, during the operation of the third drive motor 31, the output shaft of the third drive motor 31 drives the driving wheel 32, the driven wheel 33 and the synchronous belt 34 to rotate, and the lifting component 2 is fixed to the fixed position of the synchronous belt 34, and the fixed position always moves horizontally left and right during the operation of the third drive motor 31, driving the lifting component 2 to also move horizontally left and right.

[0067] In some application scenarios, the moving component 3 and the lifting component 2 can drive the rotating mixing component 1 to the top of the heating component 4 to work, and can also drive the rotating mixing component 1 to a non-working position to clean and replace components.

[0068] Based on the above technical features, the high-throughput automatic nucleic acid extractor of the embodiment of the present disclosure can perform nucleic acid extraction work such as automatic heating and mixing, and at the same time, by improving the structure of the rotating mixing component 1 and the heating component 4, it is possible to extract nucleic acids from multiple groups of extracts at the same time, thereby improving the efficiency of the nucleic acid extraction process. Furthermore, the mixing operation of the extracts to be extracted by rotation avoids problems such as high noise and bubbles caused by shaking or blowing mixing methods.

[0069] This specification uses embodiments to disclose the present application, including the best embodiment, and also enables those skilled in the art to practice the present application, including making and using any device or system and performing any incorporated method. The embodiments of the present application and the technical solutions obtained by slightly changing the embodiments are all within the protection scope of the present application.

Claims

1. A high-throughput automatic nucleic acid extractor, characterized in that: include: Rotating mixing component, heating component, lifting component and moving component; The mobile assembly includes a mobile part and a base plate; The heating component is fixed above the bottom plate and is used to heat the extract; The moving component is arranged above the bottom plate and located on the side of the heating assembly; The lifting assembly is connected to the moving component and is used to move horizontally along with the moving component on one side of the heating assembly; The rotating mixing component is fixedly connected to the lifting component and is used for vertically moving with the lifting component.

2. The high-throughput automatic nucleic acid extractor according to claim 1, characterized in that: The rotating mixing assembly comprises a first support plate, a first magnetic rod set, a second magnetic rod set and a third magnetic rod set, each of the magnetic rod sets comprises a preset number of magnetic rod sets that are fixedly spaced and arranged in a straight line; The first magnetic rod set, the second magnetic rod set and the third magnetic rod set are positioned in parallel and are respectively arranged on the left side, the middle and the right side of the first support plate, wherein each magnetic rod set is located on the bottom surface of the first support plate and is perpendicular to the bottom surface.

3. The high-throughput automatic nucleic acid extractor according to claim 2, characterized in that: The rotating mixing assembly also includes a first driving motor, a first transmission assembly and a second transmission assembly; The first driving motor is fixed to one side of the first supporting plate and is located between the first magnetic bar set and the second magnetic bar set; The first transmission assembly is connected to the first drive motor, the first magnetic rod set and the second magnetic rod set, and is used to drive each of the magnetic rod sets in the first magnetic rod set and the second magnetic rod set to rotate; The second rotating assembly is connected to the second magnetic bar set and the third magnetic bar set, and is used to drive the third magnetic bar set to rotate when the second magnetic bar set rotates.

4. The high-throughput automatic nucleic acid extractor according to claim 2, characterized in that: The lifting assembly includes a second driving motor and a first driven module; The second driving motor is used to drive the first driven module to move vertically; The first driven module is fixedly connected to the first supporting plate.

5. The high-throughput automatic nucleic acid extractor according to claim 4, characterized in that: The first driven module includes a lead screw and a rotating nut; The output shaft of the second drive motor is fixedly connected to the lead screw; The inner side of the rotating nut is threadedly connected to the lead screw, and the outer side is connected to the rotating mixing component.

6. The high-throughput automatic nucleic acid extractor according to claim 5, characterized in that: The lifting assembly also includes a vertical support arranged in a vertical direction; The second driving motor is fixedly connected to the vertical support.

7. The high-throughput automatic nucleic acid extractor according to claim 1, characterized in that: The moving component includes a third driving motor and a second driven module; The third driving motor is fixed to the base plate, and the second driven module is fixedly connected to the lifting assembly.

8. The high-throughput automatic nucleic acid extractor according to claim 7, characterized in that: The second driven module includes a driving wheel, a driven wheel and a synchronous belt; The driving wheel and the driven wheel are connected via the synchronous belt; The rotating shaft of the driving wheel is fixedly connected to the output shaft of the third driving motor; The synchronous belt is fixedly connected to the lifting assembly.

9. The high-throughput automatic nucleic acid extractor according to claim 1, characterized in that: The heating assembly includes a second support plate and at least one heating seat; The heating seat is fixed in parallel above the second support plate at a fixed interval, and is used for placing the extract to be extracted and heating the extract to be extracted.

10. The high-throughput automatic nucleic acid extractor according to claim 9, characterized in that: The heating assembly also includes a control system corresponding to each of the heating seats; The control system is arranged at a position below the second supporting plate corresponding to the heating seat.