Thrombus detector

By using artificial blood vessel placement rings and gas to push out the thrombus in the thrombus detector, the problem of instability in thrombus reflux is solved, and the accuracy and reliability of thrombus detection is achieved.

CN119438561APending Publication Date: 2025-02-14HAINING TRADITIONAL CHINESE MEDICINE HOSPITAL
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Patent Information

Application Number
CN202411663424.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-11-20
Publication Date
2025-02-14

AI Technical Summary

Technical Problem

Existing thrombosis detectors may affect the accuracy of the detection after centrifugation of samples, especially improper decanting time may lead to dispersion or deformation of the thrombus.

Method used

A thrombosis detector was designed, using an artificial blood vessel placement ring and an auxiliary experimental mechanism. After centrifugation through a centrifugation mechanism, the thrombus was pushed out onto the test strip by using a gas-generating mechanism to achieve stable and accurate detection of the thrombus.

Benefits of technology

The method of pushing out the thrombus through gas solves the problem of instability in the thrombus reflux, which affects the accuracy of detection and reliability of thrombus detection.

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Abstract

The invention discloses a thrombus detector, and relates to the field of thrombus detection, the thrombus detector comprises a fixed shell, a centrifugal mechanism is installed in the fixed shell, an artificial blood vessel placing ring is detachably installed at the top of the centrifugal mechanism, the artificial blood vessel placing ring is composed of a plurality of connecting blocks, and the adjacent connecting blocks are rotatably connected through a rotating shaft. An artificial blood vessel injected with a sample is placed in an artificial blood vessel placing ring, a centrifugal mechanism performs centrifugal work, after centrifugation is completed, the artificial blood vessel placing ring is placed on a placing table to be fixed, the placing table is tilted after fixing, one end of the artificial blood vessel makes contact with test paper, and at the moment, a protective shell and the placing table are pulled towards one side; in the moving process of the protective shell, the auxiliary test mechanism inflates the interior of the artificial blood vessel, the thrombus in the artificial blood vessel is pushed out through the gas, and due to the fact that the thrombus is pushed out through the gas, the thrombus is pushed out more stably, and thrombus detection is more accurate.
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Description

Technical Field

[0001] The present invention relates to the field of thrombus detection, in particular to a thrombus detector. Background Art

[0002] A thrombus detector is a medical device used to detect and analyze thrombosis. This device plays an important role in medical diagnosis, helping doctors understand the patient's thrombosis condition and thus provide targeted treatment. The working principle of a thrombus detector is mainly based on centrifugal technology. During the detection process, the instrument simulates the temperature and blood circulation speed in the human body, and gathers the thrombosis factors in the blood sample through centrifugation. By observing and analyzing parameters such as the length, dry weight and wet weight of the formed thrombus, doctors can determine the degree and type of thrombosis.

[0003] When using a thrombus detector, you first need to prepare a clean plastic tube and syringe, and take venous blood as a sample. Then, inject the blood sample into a plastic ring, connect it into a ring, put it on the plexiglass, and place it on the turntable of the instrument. After starting the instrument, the motor starts to rotate and the spotlight lights up for easy observation. As the turntable rotates, a thrombus gradually forms. The instrument will automatically alarm after a set time, indicating that the test is complete. At this time, you can remove the plexiglass ring to observe and analyze the shape and size of the thrombus.

[0004] From the operation of the above-mentioned thrombus detector, it can be seen that the blood sample needs to be injected into a plastic tube and then centrifuged, but the pouring time of different samples in the same batch will affect the thrombus detection. Too long pouring time may cause the thrombus to disperse or deform, while too short pouring time may cause the thrombus to fail to form or fix completely. In addition, the thrombus is generally poured out manually or with tools, and it is difficult to control the pouring rhythm of the thrombus, which may adversely affect the accuracy of thrombus detection. Summary of the invention

[0005] Based on this, the purpose of the present invention is to provide a thrombus detector to solve the technical problem that the thrombus may be poured out after the sample is centrifuged in the general thrombus detector, which may have an adverse effect on the accuracy of thrombus detection.

[0006] To achieve the above-mentioned object, the present invention provides the following technical solutions: a thrombus detector, comprising a fixed shell, a centrifugal mechanism is installed inside the fixed shell, an artificial blood vessel placement ring is detachably installed on the top of the centrifugal mechanism, the artificial blood vessel placement ring is composed of a plurality of connecting blocks, adjacent connecting blocks are rotatably connected by a rotating shaft, a mounting groove is provided on the surface of the connecting block, the connecting blocks at the head end and the tail end of the artificial blood vessel placement ring are provided with a mounting mechanism, and the artificial blood vessel placement ring is connected head to tail through the mounting mechanism;

[0007] A detection mechanism is provided at a recessed portion on the surface of the fixed shell, the detection mechanism comprises a protective shell, the protective shell is slidably connected to a surface track of the fixed shell, the top of the protective shell is rotatably connected to a placement table via a rotating shaft, a plurality of blocks are fixedly provided on the top of the placement table, the shape and size of the blocks match the gaps between the connection blocks, an auxiliary experimental mechanism is provided inside the protective shell, an air outlet end of the auxiliary experimental mechanism is connected to an artificial blood vessel inside the mounting groove, and a test paper is provided below the protective shell.

[0008] The present invention is further configured as follows: the auxiliary experimental mechanism includes a hose, a fixed block, an air outlet pipe, a positioning shell, a connecting pipe and a second spring; a fixed block is slidably provided at one end of the placing table; a gas generating mechanism is installed inside the protective shell; a hose is connected to the air outlet of the gas generating mechanism; one end of the hose is connected to the positioning shell; a connecting pipe is slidably connected to one side of the positioning shell; one end of the connecting pipe is connected to the air outlet pipe on the surface of the fixed block; and a second spring is connected between the fixed block and the positioning shell.

[0009] The present invention is further configured such that the gas generating mechanism includes an air pump and a gear set mechanism, the air pump is installed inside the protective shell, the gear set mechanism is installed on the top of the air pump, and the gear set mechanism is connected to the impeller inside the air pump.

[0010] The present invention is further configured such that the fixed shell is adapted to be equipped with a rack that cooperates with the gear set mechanism in the surface track on which the protective shell slides, a portion of a gear of the gear set mechanism is located outside the protective shell, and the gear is meshed with the rack, and when the protective shell slides, the gear and rack are meshed with each other to drive the gear set mechanism to operate.

[0011] The present invention is further configured as follows: the centrifugal mechanism includes a mounting disk, a snap mechanism, a motor and a mounting frame, the motor is installed on the mounting frame inside the fixed shell, the output end of the motor is connected to the mounting disk, the mounting disk is in the shape of a boss, the artificial blood vessel placement ring is arranged on the top of the mounting disk, the snap mechanism includes a button, the button is movably arranged on the top of the mounting disk, one end of the button is rotatably connected to a connecting rod, one end of the connecting rod is rotatably connected to an insert block, a reset spring is arranged at the bottom end of the button, and the mounting disk and the output shaft of the motor are connected by a fixed spring.

[0012] The present invention is further configured as follows: the installation mechanism includes a sliding block, a limit block and a first spring; the limit block is slidably arranged in the groove on the connecting block at the head end of the artificial blood vessel placement ring; the limit block and the groove are connected by the first spring; and a sliding block is slidably arranged in the groove of the connecting block at the tail end of the artificial blood vessel placement ring; the sliding block can be inserted into the groove of the connecting block at the tail end and cooperate with the limit block.

[0013] The present invention is further configured such that a connecting groove is provided inside the mounting groove of the connecting block at the tail end of the artificial blood vessel placement ring, and the shape and size of the connecting groove match the air outlet pipe.

[0014] The present invention is further configured such that a support rod is provided between the placement platform and the protective shell, and hinge structures are provided at both ends of the support rod.

[0015] The present invention is further configured such that a scale is slidably provided on the surface of the fixed shell at one side of the auxiliary experimental mechanism.

[0016] The present invention is further configured such that a sealing cover is provided on the top surface of the fixed shell.

[0017] In summary, the present invention mainly has the following beneficial effects: the present invention places an artificial blood vessel filled with a sample into an artificial blood vessel placement ring, and a centrifugal mechanism performs centrifugal work. After the centrifugation is completed, the artificial blood vessel placement ring is placed on a placement table for fixation. After fixation, the placement table is tilted up, and one end of the artificial blood vessel contacts the test paper. At this time, the protective shell and the placement table are pulled to one side. During the movement, the protective shell is inflated into the artificial blood vessel by the auxiliary test mechanism, and the thrombus in the artificial blood vessel is pushed out by the gas. Since the thrombus is pushed out by the gas, the thrombus is pushed out more smoothly and the thrombus detection is more accurate. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is a schematic diagram of the three-dimensional structure of the present invention;

[0019] Figure 2 It is a schematic diagram of the tilted state of the placement table of the present invention;

[0020] Figure 3 This is a schematic diagram of the internal structure of the protective shell of the present invention;

[0021] Figure 4 It is a schematic diagram of the internal structure of the fixed shell of the present invention;

[0022] Figure 5 It is a schematic diagram of the internal structure of the sealing cover of the present invention;

[0023] Figure 6 For the present invention Figure 2 A magnified image of point A;

[0024] Figure 7 For the present invention Figure 3 A magnified view of the structure at B;

[0025] Figure 8 This is a schematic diagram of the bottom structure of the placement table of the present invention;

[0026] Fig. 9 It is a schematic diagram of the internal structure of the installation disk of the present invention;

[0027] Fig.10 It is a schematic diagram of the structural connection between the artificial blood vessel placement ring and the connecting block of the present invention.

[0028] In the figure: 1. fixed shell; 2. placing table; 3. clamping block; 4. connecting block; 5. mounting groove; 6. sliding block; 7. limiting block; 8. first spring; 9. connecting groove; 10. mounting plate; 11. buckle mechanism; 12. motor; 13. mounting frame; 14. support rod; 15. protective shell; 16. hose; 17. air pump; 18. gear set mechanism; 19. fixed block; 20. air outlet pipe; 21. ruler; 22. sealing cover; 23. positioning shell; 24. connecting pipe; 25. second spring; 26. test paper; 27. button; 28. connecting rod; 29. ​​plug-in block; 30. reset spring; 31. fixing spring. DETAILED DESCRIPTION

[0029] The following will be combined with the accompanying drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and cannot be understood as limiting the present invention.

[0030] All the items mentioned in the present invention can be obtained in the market or through private ordering.

[0031] A thrombus detector, such as Figure 1-10 As shown, it includes a fixed shell 1, and a centrifugal mechanism is installed inside the fixed shell 1. The centrifugal mechanism includes a motor 12. The motor 12 is installed on a mounting frame 13 inside the fixed shell 1. The output shaft of the motor 12 is connected to a mounting disk 10. The mounting disk 10 is in a boss shape. The mounting disk 10 and the output shaft of the motor 12 are connected by a snap mechanism 11. The snap mechanism 11 includes a button 27. The button 27 is movably arranged on the top of the mounting disk 10. One end of the button 27 is rotatably connected to a connecting rod 28. One end of the connecting rod 28 is rotatably connected to an insert block 29. A reset spring 30 is arranged at the bottom end of the button 27. The mounting disk 10 and the output shaft of the motor 12 are connected by a fixed spring 31. The artificial blood vessel placement ring is arranged on the top of the mounting disk 10.

[0032] That is, when the mounting disk 10 needs to be ejected from the output shaft of the motor 12, the button 27 is pressed downward so that the button 27 squeezes the reset spring 30 until the connecting rod 28 drives the insert block 29 to disengage from the slot. At this time, the fixation is released, and the fixing spring 31 ejects the mounting disk 10. When the mounting disk 10 needs to be reset, the mounting disk 10 is squeezed downward until the insert block 29 is reinserted into the slot to achieve the reset of the mounting disk 10.

[0033] The artificial blood vessel placement ring is composed of a plurality of connection blocks 4, which are rotatably connected by a rotating shaft, and the head and tail connection blocks 4 are connected to each other by a mounting mechanism, and the mounting mechanism includes a sliding block 6, and a limit block 7 is slidably arranged in the groove on the head end connection block 4 of the artificial blood vessel placement ring, and the limit block 7 is connected to the groove by a first spring 8, and a sliding block 6 is slidably arranged in the groove of the tail end connection block 4 of the artificial blood vessel placement ring, and the sliding block 6 can be inserted into the groove of the tail end connection block 4 and matched with the limit block 7;

[0034] When it is necessary to connect the ends of the artificial blood vessel placement ring, insert the sliding block 6 into the groove inside the tail end connecting block 4 and cooperate with the limit block 7. One end of the limit block 7 is arc-shaped, and the surface of the sliding block 6 is provided with a slot that cooperates with the arc of one end of the limit block 7. After the sliding block 6 is inserted into the limit block 7, the first spring 8 will be squeezed until the limit block 7 is inserted into the slot, thereby realizing the end-to-end connection of the artificial blood vessel placement ring. After the end-to-end connection is completed, the artificial blood vessel can be placed in the mounting groove 5 on the surface of the connecting block 4. At this time, the artificial blood vessel placement ring is placed in the centrifugal mechanism for centrifugal work.

[0035] Furthermore, the mounting mechanism can effectively prevent the artificial blood vessel placement ring from detaching when it is placed on the centrifugal mechanism for centrifugal work. When centrifuging, under the action of centrifugal force, the limit block 7 will be inserted into the slot in the sliding block 6, making it tighter, so that unlocking will not occur, and the tightening effect is better.

[0036] After the centrifugation is completed, the sealing cover 22 disposed on the top surface of the fixed shell 1 can be opened, the artificial blood vessel placement ring inside can be taken out, and the sliding block 6 can be pulled to one side to separate the sliding block 6 from the squeezing of the limiting block 7, thereby realizing the separation of the head and tail connecting blocks 4;

[0037] At this time, the unfolded artificial blood vessel placement ring can be placed in a detection mechanism for detection. The detection mechanism includes a protective shell 15, which is slidably connected to the surface track of the fixed shell 1. The top of the protective shell 15 is rotatably connected to the placement table 2 through a rotating shaft. A plurality of clamping blocks 3 are fixedly arranged on the top of the placement table 2. The clamping blocks 3 can be inserted into the gaps between the connecting blocks 4, so that the artificial blood vessel placement ring can be fixed on the placement table 2. Then, the placement table 2 is rotated upward along the rotating shaft and supported by the support rod 14 arranged between the placement table 2 and the protective shell 15. At this time, the obliquely arranged placement table 2 will make one end of the artificial blood vessel contact the test paper 26 under the protective shell 15, and then prepare for the subsequent thrombus discharge work;

[0038] After the artificial blood vessel placement ring is installed, the protective shell 15 is pulled to one side. The protective shell 15 will drive the placement table 2 to move synchronously during the movement, and an auxiliary experimental mechanism is installed inside the protective shell 15 to discharge the thrombus in the artificial blood vessel.

[0039] The auxiliary experimental mechanism includes a gas generating mechanism, the gas outlet of the gas generating mechanism is connected to a hose 16, one end of the hose 16 is connected to a positioning shell 23, one side of the positioning shell 23 is slidably connected to a connecting pipe 24, one end of the connecting pipe 24 is connected to an outlet pipe 20 on the surface of the fixed block 19, and a second spring 25 is connected between the fixed block 19 and the positioning shell 23. The gas generated by the gas generating mechanism will enter the positioning shell 23 through the hose 16 and be discharged by the connecting pipe 24. Since the connecting pipe 24 and the positioning shell 23 are slidably connected and the two are slidably sealed, when installing the artificial blood vessel placement ring, the fixed block 19 can be pulled to one side, and under the action of the second spring 25, the outlet pipe 20 on the surface of the fixed block 19 is connected to the artificial blood vessel.

[0040] Therefore, after the gas generating mechanism generates gas, the gas will enter the positioning shell 23 through the hose 16, and be discharged through the connecting tube 24, and then enter the outlet pipe 20 and be sprayed out. Since the outlet pipe 20 is connected to the artificial blood vessel, the gas will push the thrombus in the artificial blood vessel to be discharged onto the test paper 26.

[0041] The gas generating mechanism includes an air pump 17 and a gear set mechanism 18. The air pump 17 is installed inside the protective shell 15. The gear set mechanism 18 is installed on the top of the air pump 17. The gear set mechanism 18 is connected to the impeller inside the air pump 17. The fixed shell 1 is adapted to be arranged in the surface track of the sliding of the protective shell 15, and a rack matching the gear set mechanism 18 is arranged. A part of a gear of the gear set mechanism 18 is located outside the protective shell 15, and the gear is meshed with the rack. When the protective shell 15 slides, the gear and rack are meshed with each other to drive the gear set mechanism 18 to operate. Therefore, when the protective shell 15 moves forward, the gear of the gear set mechanism 18 located outside the protective shell 15 will mesh and rotate with the rack, thereby driving the overall gear set mechanism 18 to operate, so that the air pump 17 works and gas is filled into the hose 16 to facilitate subsequent thrombus discharge.

[0042] A connecting groove 9 is provided inside the mounting groove 5 of the connecting block 4 at the tail end of the artificial blood vessel placement ring. The shape and size of the connecting groove 9 match the air outlet pipe 20. After the artificial blood vessel placement ring is fixed on the placement table 2, the fixing block 19 is pulled to one side, and under the action of the second spring 25, the air outlet pipe 20 on the surface of the fixing block 19 is connected to the artificial blood vessel. The position of the air outlet pipe 20 at this time is the connecting groove 9, which plays a positioning role.

[0043] Furthermore, the artificial blood vessel is placed in the mounting groove 5 on the surface of the connection block 4. When the artificial blood vessel placement ring is not connected end to end, one end of the artificial blood vessel is located outside the connection block 4, and the other end is received inside the connection block 4. Therefore, after the end to end connection, the end of the artificial blood vessel located outside can be just inserted into the connection block 4 at the other end, and contact and seal with the end of the artificial blood vessel inside the connection block 4, so that the two ends of the artificial blood vessel are sealed;

[0044] At the same time, since one end of the artificial blood vessel in the unfolded state extends out of the connecting block 4, when it is installed on the placement table 2, when the placement table 2 is tilted upward, the artificial blood vessel just contacts the surface of the test paper 26, making it easier to discharge the thrombus.

[0045] The surface of the fixed shell 1 is slidably provided with a ruler 21 on one side of the auxiliary experimental mechanism. When the auxiliary experimental mechanism pulls to one side and pushes out the thrombus inside the artificial blood vessel, since the thrombus may not be pushed out directly from the starting position, the position of the ruler 21 can be adjusted to facilitate the subsequent determination of the thrombus length.

[0046] Although an embodiment of the present invention has been shown and described, this specific embodiment is merely an explanation of the present invention and is not a limitation of the invention. The specific features, structures, materials or characteristics described may be combined in a suitable manner in any one or more embodiments or examples. After reading this specification, those skilled in the art may make modifications, substitutions and variations to the embodiments without creative contributions as needed without departing from the principles and purpose of the present invention. However, as long as they are within the scope of the claims of the present invention, they are protected by patent law.

Claims

1. A thrombus detector, comprising a fixed housing (1), characterized in that: A centrifugal mechanism is installed inside the fixed shell (1), and an artificial blood vessel placement ring is detachably installed on the top of the centrifugal mechanism. The artificial blood vessel placement ring is composed of a plurality of connecting blocks (4), and adjacent connecting blocks (4) are rotatably connected via a rotating shaft. The surfaces of the connecting blocks (4) are provided with mounting grooves (5). The connecting blocks (4) at the head and tail ends of the artificial blood vessel placement ring are provided with mounting mechanisms, and the artificial blood vessel placement rings are connected head to tail via the mounting mechanisms. A detection mechanism is arranged at a recessed position on the surface of the fixed shell (1), and the detection mechanism comprises a protective shell (15), the protective shell (15) is slidably connected to a surface track of the fixed shell (1), the top of the protective shell (15) is rotatably connected to a placement table (2) via a rotation axis, a plurality of card blocks (3) are fixedly arranged on the top of the placement table (2), the shape and size of the card blocks (3) match the gaps between the connection blocks (4), an auxiliary experimental mechanism is arranged inside the protective shell (15), an air outlet end of the auxiliary experimental mechanism is connected to an artificial blood vessel inside the mounting groove (5), and a test paper (26) is arranged below the protective shell (15).

2. A thrombus detector according to claim 1, characterized in that: The auxiliary experimental mechanism comprises a hose (16), a fixed block (19), an air outlet pipe (20), a positioning shell (23), a connecting pipe (24) and a second spring (25); a fixed block (19) is slidably provided at one end of the placing table (2); a gas generating mechanism is installed inside the protective shell (15); a hose (16) is connected to the air outlet of the gas generating mechanism; one end of the hose (16) is connected to the positioning shell (23); a connecting pipe (24) is slidably connected to one side of the positioning shell (23); one end of the connecting pipe (24) is connected to the air outlet pipe (20) on the surface of the fixed block (19); and a second spring (25) is connected between the fixed block (19) and the positioning shell (23).

3. A thrombus detector according to claim 2, characterized in that: The gas generating mechanism comprises an air pump (17) and a gear set mechanism (18); the air pump (17) is installed inside the protective shell (15); the gear set mechanism (18) is installed on the top of the air pump (17); and the gear set mechanism (18) is connected to an impeller inside the air pump (17).

4. A thrombus detector according to claim 3, characterized in that: The fixed shell (1) is adapted to be arranged in a surface track on which the protective shell (15) slides, and a rack matched with the gear set mechanism (18) is arranged. A portion of a gear of the gear set mechanism (18) is located outside the protective shell (15), and the gear is meshed with the rack. When the protective shell (15) slides, the gear and the rack are meshed with each other to drive the gear set mechanism (18) to operate.

5. The thrombus detector according to claim 1, characterized in that: The centrifugal mechanism comprises a mounting plate (10), a buckle mechanism (11), a motor (12) and a mounting frame (13); the motor (12) is mounted on the mounting frame (13) inside the fixed shell (1); the output end of the motor (12) is connected to the mounting plate (10); the mounting plate (10) is in the shape of a boss; the artificial blood vessel placement ring is sleeved on the top of the mounting plate (10); the buckle mechanism (11) comprises a button (27); the button (27) is movably arranged on the top of the mounting plate (10); one end of the button (27) is rotatably connected to a connecting rod (28); one end of the connecting rod (28) is rotatably connected to an insert block (29); a reset spring (30) is arranged at the bottom end of the button (27); the mounting plate (10) and the output shaft of the motor (12) are connected via a fixing spring (31).

6. The thrombus detector according to claim 1, characterized in that: The installation mechanism comprises a sliding block (6), a limiting block (7) and a first spring (8); the limiting block (7) is slidably arranged in the groove on the connecting block (4) at the head end of the artificial blood vessel placement ring; the limiting block (7) and the groove are connected via the first spring (8); the sliding block (6) is slidably arranged in the groove of the connecting block (4) at the tail end of the artificial blood vessel placement ring; the sliding block (6) can be inserted into the groove of the connecting block (4) at the tail end to cooperate with the limiting block (7).

7. The thrombus detector according to claim 1, characterized in that: A connecting groove (9) is provided inside the mounting groove (5) of the connecting block (4) at the tail end of the artificial blood vessel placement ring, and the shape and size of the connecting groove (9) match the air outlet pipe (20).

8. The thrombus detector according to claim 1, characterized in that: A support rod (14) is provided between the placement platform (2) and the protective shell (15), and hinge structures are provided at both ends of the support rod (14).

9. The thrombus detector according to claim 1, characterized in that: A scale (21) is slidably provided on the surface of the fixed shell (1) at one side of the auxiliary experimental mechanism.

10. The thrombus detector according to claim 1, characterized in that: A sealing cover (22) is provided on the top surface of the fixed shell (1).