Deep pipeline medicine applying head for living body and preparation method of deep pipeline medicine applying head

Abstract

The invention provides a deep conduit medicine applying head for an organism and a preparation method thereof, the deep conduit medicine applying head comprises a medicine applying part coated with a medicine in advance and used for applying the medicine to a target part of the organism, and a medicine applying part coated with the medicine in advance and used for applying the medicine to the target part of the organism; the medicine applying part comprises a medicine applying conical cavity and a medicine applying bag; the medicine application conical cavity is made of an elastic material, is in an elastic cone shape, is driven to stretch out and draw back and drives the medicine application part to stretch into and stretch out of human tissues; the medicine applying bag is made of a deformable flexible material and is arranged at the peripheral position of the medicine applying conical cavity, the medicine applying bag has a folded state and an opened state, the instrument conveying radius of the deep pipeline medicine applying head is reduced when the medicine applying bag is folded, and the medicine applying part is opened to a proper position and is tightly attached to human tissues when the medicine applying part is opened; the driving mechanism is in transmission connection with the pesticide applying part and is used for driving the pesticide applying part to be switched between the folded state and the unfolded state. By means of the structure, the pesticide applying difficulty can be effectively reduced, it is guaranteed that pesticide is evenly applied, and missing parts are reduced.

Description

Technical Field

[0001] The invention relates to the technical field of medical instruments, and in particular to a deep channel applicator and a medicine injector for a biological body. Background Art

[0002] There are various deep pipes in the intestines, cervix and other locations of the human body and other organisms. There are certain difficulties in administering drugs in a limited area in the above-mentioned pipeline system. In the prior art, it is often dependent on the skills of medical workers to extend gauze or dressing catheters into the body for drug coating or use non-precise liquid drug infusion or placement of soluble drug suppositories. However, the above-mentioned treatment methods are heavily dependent on the technical level of medical workers, not only have the problems of complicated operation and poor patient experience, but also are prone to uneven and inaccurate drug coating and missed drug administration sites, affecting the treatment effect. Summary of the invention

[0003] The technical problem to be solved by the present invention is that it is difficult to accurately administer drugs on the surface of deep channels of organisms in the prior art, which is heavily dependent on the technical level of medical workers, complicated operation, poor patient experience, and uneven and inaccurate drug coating. The present invention provides a drug application head and a drug injector for deep channels of organisms that are easy to operate and have uniform drug coating.

[0004] According to the present invention, there is provided a deep channel applicator for a living body, comprising:

[0005] The medicine application part is pre-coated with medicine and is used to apply medicine to the target part of the biological body; the medicine application part comprises: a medicine application cone cavity and a medicine application bag; the medicine application cone cavity is made of elastic material, and is in the shape of an elastic cone, which is driven to stretch and retract and drive the medicine application part to extend into and out of human tissue; the medicine application bag is made of deformable flexible material, and is arranged at the peripheral position of the medicine application cone cavity. The medicine application bag has a folded state and an opened state. When folded, the instrument delivery radius of the deep channel medicine application head is reduced, and when opened, the medicine application part is opened to a proper position and closely fits the human tissue;

[0006] The driving mechanism is connected to the medicine dispensing part in a transmission manner and is used for driving the medicine dispensing part to switch between the folded state and the opened state.

[0007] Optionally, a deep channel applicator for a living body may also include:

[0008] The support assembly comprises: a support member and an outer sleeve sleeved outside the support member; the support member and the outer sleeve are slidably connected; the drug application part is arranged at the end position of the support assembly;

[0009] The driving mechanism comprises:

[0010] The opening and closing assembly comprises: an outer connecting rod and an inner connecting rod, wherein the inner connecting rod is hingedly fixed to a support member fixing portion close to the head portion of the support member; the outer connecting rod is hingedly fixed to an outer sleeve fixing portion at the head end of the outer sleeve; and the opening and closing assembly is used to support the medication application portion; the outer sleeve and the support member are relatively displaced to realize the folding and opening action of the opening and closing assembly.

[0011] Optionally, the medicine application conical cavity of the medicine application part is arranged at the end position of the outer sleeve of the opening and closing component; the medicine application bag of the medicine application part is fixed on the outer connecting rod and the inner connecting rod, and is arranged toward the direction of human tissue;

[0012] When the opening and closing assembly is in the open state, the outer sleeve and the support member move relative to each other in one direction, and the inner connecting rod and the outer connecting rod open in conjunction with each other, so as to prop the medication application part to an appropriate position for medication application; when the opening and closing assembly is in the folded state, the outer sleeve and the support member move relative to each other in the other direction, and the inner connecting rod and the outer connecting rod open in conjunction with each other and approach the opening and closing assembly, so as to facilitate the deep channel medication application head to extend into the biological body.

[0013] Optionally, the outer sleeve is driven to slide on the support member; when the outer sleeve is driven to move toward a medication application direction, the opening and closing assembly gradually opens; when the outer sleeve is driven to move away from the medication application direction, the opening and closing assembly gradually folds.

[0014] Optionally, the medicine applying part further comprises: an elastic support, which is arranged on the medicine applying conical cavity; the elastic support wraps the medicine applying conical cavity;

[0015] The driving mechanism comprises: an opening and closing driving sleeve, wherein the medicine dispensing part is arranged in the inner cavity of the opening and closing driving sleeve; the opening and closing driving sleeve and the medicine dispensing part are relatively displaced so that the medicine dispensing part can realize folding and opening actions; in the open state, the elastic bracket opens and closely fits human tissue under the action of its own elastic force; in the folded state, the elastic bracket is compressed in the opening and closing driving sleeve.

[0016] Optionally, the outer periphery of the elastic support is closely connected to the inner wall of the opening and closing driving sleeve, so that the medicine applying part is limitedly fixed in the opening and closing driving sleeve;

[0017] When the medication application part is in the open state, the opening and closing drive sleeve and the medication application part move relative to each other in one direction, the medication application part gradually breaks away from the restraint of the opening and closing drive sleeve, and the medication application part opens to an appropriate position under the action of its own elastic restoring force; when the medication application part is in the folded state, the opening and closing drive sleeve and the medication application part move relative to each other in the other direction, and the opening and closing drive sleeve is close to the top of the medication application part to facilitate the medication head to extend into the biological body.

[0018] Optionally, the elastic support is a nickel-titanium alloy mesh;

[0019] A diaphragm is arranged on the outer surface of the elastic support; the diaphragm is used to prevent medicine from entering the elastic support.

[0020] Optionally, the opening and closing drive sleeve is driven to telescope relative to the medicine application conical cavity; when the opening and closing drive sleeve is driven to move away from the medicine application direction, the elastic bracket gradually opens; when the opening and closing drive sleeve is driven to move toward the medicine application direction, the elastic bracket gradually folds.

[0021] Optionally, the elastic support is fixedly arranged on the medicine compress conical cavity, and the medicine compress bag is a flexible membrane whose outer periphery is fixedly arranged on the elastic support and the medicine compress conical cavity.

[0022] A method for preparing a deep channel applicator head, comprising:

[0023] The first step: preparing a deep channel applicator head including a drug application part and a driving mechanism; wherein the drug application conical cavity is in an elastic cone shape, and is driven to extend and retract and drive the drug application part to extend into and out of human tissue; the drug application bag is a deformable flexible material, and has a folded state and an open state. When folded, the instrument delivery radius of the deep channel applicator head is reduced, and when opened, the drug application part is opened to an appropriate position and closely fits the human tissue;

[0024] The second step: mixing and stirring the drug component ingredients to a uniform mixture, wherein the drug component ingredients include 5-aminolevulinic acid or 5-aminolevulinic acid, glycerol and carbomer;

[0025] The third step: heating the fatty acid glyceride into a liquid solution;

[0026] Step 4: adding the mixture obtained in step 2 to the liquid solution obtained in step 3, and stirring until the mixture reaches a uniform state to prepare a photosensitizer gel solution;

[0027] Step 5: Open the application part of the deep channel applicator obtained in the first step, and insert it into the photosensitizer gel solution obtained in the fourth step, so that a layer of photosensitizer gel solution is coated on the surface of the application part;

[0028] Step 6: Take out the application part with a layer of photosensitizer gel liquid coated on the surface, and cool the photosensitizer gel liquid into a solid photosensitizer coating; then, return the application part to the folded state through the driving mechanism to complete the photosensitizer pre-coating work.

[0029] The technical solution of the present invention has the following advantages:

[0030] 1. The deep channel applicator for a living body provided by the present invention comprises:

[0031] The medicine application part is pre-coated with medicine and is used to apply medicine to the target part of the biological body; the medicine application part comprises: a medicine application cone cavity and a medicine application bag; the medicine application cone cavity is made of elastic material, and is in the shape of an elastic cone, which is driven to stretch and retract and drive the medicine application part to extend into and out of human tissue; the medicine application bag is made of deformable flexible material, and is arranged at the peripheral position of the medicine application cone cavity. The medicine application bag has a folded state and an opened state. When folded, the instrument delivery radius of the deep channel medicine application head is reduced, and when opened, the medicine application part is opened to a proper position and closely fits the human tissue;

[0032] The driving mechanism is connected to the medicine dispensing part in a transmission manner and is used for driving the medicine dispensing part to switch between the folded state and the opened state.

[0033] In the present invention, the above-mentioned compress conical cavity and compress capsule constitute the compress portion, so that the compress portion is more suitable for the patient's position. Moreover, the above-mentioned compress conical cavity is made of elastic material, which is convenient for medical workers to insert the deep pipeline compress head. In addition, the compress capsule is made of flexible material, which can allow the compress capsule to expand into an appropriate shape, better fit the patient's position, and ensure the effect of compressing.

[0034] 2. The deep channel applicator for a living body provided by the present invention further comprises:

[0035] The support assembly comprises: a support member and an outer sleeve sleeved outside the support member; the support member and the outer sleeve are slidably connected; the drug application part is arranged at the end position of the support assembly;

[0036] The driving mechanism comprises:

[0037] The opening and closing assembly comprises: an outer connecting rod and an inner connecting rod, wherein the inner connecting rod is hingedly fixed to a support member fixing portion close to the head portion of the support member; the outer connecting rod is hingedly fixed to an outer sleeve fixing portion at the head end of the outer sleeve; and the opening and closing assembly is used to support the medication application portion; the outer sleeve and the support member are relatively displaced to realize the folding and opening action of the opening and closing assembly.

[0038] In the present invention, the outer connecting rod and the inner connecting rod of the opening and closing assembly can be effectively driven to move through the above-mentioned sleeved slidably connected support member and the outer sleeve outside the support member, so as to realize the opening and folding movement of the opening and closing assembly. When applying the medicine, the medicine application part is propped open, so that the medicine application part and the patient's sick position are completely fitted to ensure that the medicine is evenly applied to the patient's sick position. At the same time, when the above-mentioned opening and closing assembly is in the folded position, it is convenient for medical workers to extend the deep channel applicator head into or out of the patient's body. Moreover, the inner connecting rod and the outer connecting rod of the above-mentioned opening and closing assembly are driven by the relative movement of the outer sleeve and the support member to realize the opening and closing movement, which has the advantages of stable and reliable structure and small size.

[0039] 3. The deep channel applicator head for a biological body provided by the present invention, wherein the outer sleeve is driven to slide on the support member; when the outer sleeve is driven to move toward a medication application direction, the opening and closing assembly gradually opens; when the outer sleeve is driven to move away from the medication application direction, the opening and closing assembly gradually folds.

[0040] In the present invention, the opening and folding actions of the opening and closing assembly are realized by driving the outer sleeve to telescope and slide relative to the supporting member, which has the advantages of being convenient for medical workers to operate and having a simple and reliable structure.

[0041] 4. The deep channel applicator head for a living body provided by the present invention, the applicator portion further comprises: an elastic support, arranged on the applicator conical cavity; the elastic support wraps the applicator conical cavity;

[0042] The driving mechanism comprises: an opening and closing driving sleeve, wherein the medicine dispensing part is arranged in the inner cavity of the opening and closing driving sleeve; the opening and closing driving sleeve and the medicine dispensing part are relatively displaced so that the medicine dispensing part can realize folding and opening actions; in the open state, the elastic bracket opens and closely fits human tissue under the action of its own elastic force; in the folded state, the elastic bracket is compressed in the opening and closing driving sleeve.

[0043] In the present invention, the folding and opening of the medication application part can be effectively achieved through the relative displacement of the above-mentioned opening and closing drive sleeve and the medication application part. When the medication application part is folded, the instrument delivery radius of the medication injection head is reduced, which can facilitate medical workers to insert or withdraw the deep channel medication injection head into or out of the patient's body. When the medication application part is opened, the medication application part opens to the appropriate position and fits tightly to the human tissue, so that the medication application part and the patient's diseased position are completely fitted and the medicine is evenly applied to the patient's diseased position. The folding and opening of the elastic medication application part is achieved by the above-mentioned opening and closing drive sleeve, which has the advantages of stable and reliable structure and small size.

[0044] 5. In the deep channel applicator for a living body provided by the present invention, the outer periphery of the elastic support is closely connected to the inner wall of the opening and closing driving sleeve, so that the applicator is limitedly fixed in the opening and closing driving sleeve;

[0045] When the medication application part is in the open state, the opening and closing drive sleeve and the medication application part move relative to each other in one direction, the medication application part gradually breaks away from the restraint of the opening and closing drive sleeve, and the medication application part opens to an appropriate position under the action of its own elastic restoring force; when the medication application part is in the folded state, the opening and closing drive sleeve and the medication application part move relative to each other in the other direction, and the opening and closing drive sleeve is close to the top of the medication application part to facilitate the medication head to extend into the biological body.

[0046] In the present invention, the outer periphery of the elastic bracket is connected to the inner wall of the opening and closing driving sleeve so that the elastic bracket can be effectively limited and fixed. At the same time, the opening and folding of the elastic bracket can be completed simply and reliably.

[0047] 6. The deep channel applicator head for a living body provided by the present invention, wherein the elastic support is a nickel-titanium alloy mesh; a diaphragm is provided on the outer surface of the elastic support; the diaphragm is used to prevent the medicine from entering the elastic support.

[0048] In the present invention, the membrane can effectively prevent the medicine from penetrating into the nickel-titanium alloy mesh, thereby achieving barrier sealing of the medicine while ensuring the elastic support.

[0049] 7. The deep channel applicator head for a biological body provided by the present invention, the opening and closing driving sleeve is driven to telescope relative to the applicator conical cavity; when the opening and closing driving sleeve is driven to move away from the medication application direction, the elastic bracket gradually opens; when the opening and closing driving sleeve is driven to move toward the medication application direction, the elastic bracket gradually folds.

[0050] In the present invention, the opening and folding of the elastic support is realized by driving the opening and closing driving sleeve to telescope, which has the advantages of convenient operation for medical staff and stable and reliable structure.

[0051] 8. The deep channel applicator head for a living body provided by the present invention, wherein the elastic support is fixedly arranged on the applicator conical cavity, and the applicator bag is a flexible membrane whose outer periphery is fixedly attached to the elastic support and the applicator conical cavity.

[0052] In the present invention, the flexible film can be deformed according to the patient's affected area, so that the medication application portion of the medication application head for applying medication can be more closely fitted to the patient's affected area, ensuring uniform application of the medication.

[0053] 9. The method for preparing a deep channel applicator for a living body provided by the present invention comprises:

[0054] The first step: preparing a deep channel applicator head including a drug application part and a driving mechanism; wherein the drug application conical cavity is in an elastic cone shape, and is driven to extend and retract and drive the drug application part to extend into and out of human tissue; the drug application bag is a deformable flexible material, and has a folded state and an open state. When folded, the instrument delivery radius of the deep channel applicator head is reduced, and when opened, the drug application part is opened to an appropriate position and closely fits the human tissue;

[0055] The second step: mixing and stirring the drug component ingredients to a uniform mixture, wherein the drug component ingredients include 5-aminolevulinic acid or 5-aminolevulinic acid, glycerol and carbomer;

[0056] The third step: heating the fatty acid glyceride into a liquid solution;

[0057] Step 4: adding the mixture obtained in step 2 to the liquid solution obtained in step 3, and stirring until the mixture reaches a uniform state to prepare a photosensitizer gel solution;

[0058] Step 5: Open the application part of the deep channel applicator obtained in the first step, and insert it into the photosensitizer gel solution obtained in the fourth step, so that a layer of photosensitizer gel solution is coated on the surface of the application part;

[0059] Step 6: Take out the application part with a layer of photosensitizer gel liquid coated on the surface, and cool the photosensitizer gel liquid into a solid photosensitizer coating; then, return the application part to the folded state through the driving mechanism to complete the photosensitizer pre-coating work.

[0060] In the present invention, the photosensitizer can be pre-coated evenly on the drug application part of the deep channel drug application head by the above method. Furthermore, the use method of the above drug injection head can make it easy and convenient for medical workers to apply drugs to the patient's affected area. This effectively solves the current situation that deep channel drug application of a biological body is difficult in the prior art and is heavily dependent on the technical level of medical workers. BRIEF DESCRIPTION OF THE DRAWINGS

[0061] A more complete understanding of the present invention and its attendant advantages and features will be more readily appreciated by reference to the following detailed description taken in conjunction with the accompanying drawings, in which:

[0062] Figure 1 The schematic diagram shows the structure of the deep channel applicator in the drug application state according to the preferred embodiment 1 of the present invention;

[0063] Figure 2 The schematic diagram shows the structure of the deep channel applicator in the drug application state according to the first embodiment of the present invention;

[0064] Figure 3The schematic diagram shows the structure of the deep channel applicator in the drug application state according to the preferred embodiment 2 of the present invention;

[0065] Figure 4 The schematic diagram of the structure of the deep channel applicator head in the folded state according to the preferred embodiment 2 of the present invention is shown schematically.

[0066] Description of reference numerals:

[0067] 1-medication application part; 2-medication application conical cavity; 3-medication application bag; 4-support assembly; 5-support member; 6-outer sleeve; 7-opening and closing assembly; 8-outer connecting rod; 9-inner connecting rod; 10-support member fixing part; 11-outer sleeve fixing part; 12-elastic bracket; 13-opening and closing drive sleeve; 14-diaphragm.

[0068] It should be noted that the drawings are used to illustrate the present invention, rather than to limit the present invention. Note that the drawings showing the structures may not be drawn to scale. In addition, in the drawings, the same or similar elements are marked with the same or similar reference numerals. DETAILED DESCRIPTION

[0069] In order to make the contents of the present invention clearer and easier to understand, the contents of the present invention are described in detail below in conjunction with specific embodiments and drawings.

[0070] Example 1

[0071] <Deep channel applicator preferred embodiment 1>

[0072] Figure 1 The schematic diagram of the structure of the deep channel applicator head in the medication application state according to the preferred embodiment of the present invention is schematically shown.

[0073] like Figure 1 According to a preferred embodiment of the present invention, a deep channel applicator for a living body comprises:

[0074] The medicine application part 1 is pre-coated with medicine and is used to apply medicine to the target part of the biological body; the medicine application part 1 comprises: a medicine application conical cavity 2 and a medicine application bag 3; the medicine application conical cavity 2 is made of elastic material, and is in the shape of an elastic cone, which is driven to stretch and retract and drive the medicine application part 1 to extend into and out of human tissue; the medicine application bag 3 is made of deformable flexible material, and is arranged at the peripheral position of the medicine application conical cavity 2. The medicine application bag 3 has a folded state and an opened state. When folded, the instrument delivery radius of the deep channel medicine application head is reduced, and when opened, the medicine application part 1 is opened to a proper position and closely fits the human tissue;

[0075] The support assembly 4 comprises: a support member 5 and an outer sleeve 6 sleeved outside the support member 5; the support member 5 and the outer sleeve 6 are slidably connected; the drug application part 1 is arranged at the end position of the support assembly 4;

[0076] The driving mechanism is connected to the medicine dispensing part 1 and is used to drive the medicine dispensing part 1 to switch between the folded state and the opened state. Figure 1 and Figure 2 As shown, the driving mechanism comprises:

[0077] The opening and closing assembly 7 comprises: an outer connecting rod 8 and an inner connecting rod 9, wherein the inner connecting rod 9 is hingedly fixed to a support member fixing portion 10 of the support member 5 close to the head; the outer connecting rod 8 is hingedly fixed to an outer sleeve fixing portion 11 of the outer sleeve 6 at its head end; and the opening and closing assembly 7 is used to support the drug application portion 1 for drug application; the outer sleeve 6 and the support member 5 are relatively displaced to realize the folding and opening action of the opening and closing assembly 7.

[0078] Specifically, Figure 1 As shown, the medicine application conical cavity 2 of the medicine application part 1 is arranged at the end position of the outer sleeve 6 of the opening and closing component 7; the medicine application bag 3 of the medicine application part 1 is fixed on the outer connecting rod 8 and the inner connecting rod 9, and is arranged toward the direction of human tissue;

[0079] When the opening and closing assembly 7 is in the open state, the outer sleeve 6 and the support member 5 move relative to each other in one direction, and the inner connecting rod 9 and the outer connecting rod 8 open in conjunction with each other to open the medication application portion 1 to an appropriate position for medication application; when the opening and closing assembly 7 is in the folded state, the outer sleeve 6 and the support member 5 move relative to each other in the other direction, and the inner connecting rod 9 and the outer connecting rod 8 open in conjunction with each other and approach the opening and closing assembly 7 to facilitate the deep channel medication application head to extend into the biological body.

[0080] In this embodiment, in order to facilitate the operation of medical workers, the opening and folding actions of the opening and closing assembly 7 are realized. The medical worker drives the outer sleeve 6 to slide relative to the support member 5; when the outer sleeve 6 is driven to move toward the medication direction, the opening and closing assembly 7 gradually opens; when the outer sleeve 6 is driven to move away from the medication direction, the opening and closing assembly 7 gradually folds.

[0081] Of course, in this embodiment, the medical staff does not specifically limit the driving object of the relatively moving outer sleeve 6 and the support member 5. In other embodiments, the medical staff can also drive the support member 5, which is driven to slide on the outer sleeve 6, to achieve the folding and opening action of the opening and closing component 7.

[0082] Of course, in this embodiment, when the inner connecting rod 9 and the outer connecting rod 8 are opened in linkage to open the medicine applying portion 1, the specific shape of the medicine applying bag 3 is not specifically limited. In other embodiments, the inner connecting rod 9 and the outer connecting rod 8 are opened in linkage to open the medicine applying bag 3 to form a Figure 2 The medicine bag 3 with a raised structure is shown.

[0083] Of course, in this embodiment, the specific structures of the outer sleeve 6 and the support member 5 are not specifically limited. In other embodiments, the support member 5 can also be a sleeve structure slidably disposed in the outer sleeve 6.

[0084] Example 2

[0085] <Deep channel applicator preferred embodiment 2>

[0086] Figure 3 The schematic diagram of the structure of the deep channel applicator head in the medication application state according to the preferred embodiment of the present invention is schematically shown. Figure 4 The schematic diagram of the structure of the deep channel applicator head in the folded state according to the preferred embodiment of the present invention is schematically shown.

[0087] like Figure 3 and Figure 4 As shown, a deep channel applicator for a living body according to a preferred embodiment of the present invention comprises:

[0088] The medicine application part 1 is pre-coated with medicine and is used to apply medicine to the target part of the organism; the medicine application part 1 includes: a medicine application conical cavity 2, a medicine application bag 3 and an elastic bracket 12; the medicine application conical cavity 2 is made of elastic material, and is in the shape of an elastic cone, which is driven to stretch and retract and drive the medicine application part 1 to extend into and out of human tissue; the medicine application bag 3 is a deformable flexible material, and is arranged at the peripheral position of the medicine application conical cavity 2. The above-mentioned elastic bracket 12 is arranged on the medicine application conical cavity 2; the elastic bracket 12 wraps the medicine application conical cavity 2, and the outer peripheral edge of the elastic bracket 12 is connected to the inner wall of the opening and closing drive sleeve 13, so that the medicine application part 1 is limited and fixed in the opening and closing drive sleeve 13. The medicine bag 3 forms a folded state and an opened state by compressing and releasing the elastic support 12. When folded, the instrument delivery radius of the deep channel medicine applicator head is reduced, and when opened, the medicine application part 1 is opened to a proper position and closely fits the human tissue.

[0089] The driving mechanism is transmission-connected with the medication dispensing part 1 and is used for driving the medication dispensing part 1 to switch between the folded state and the opened state.

[0090] In this embodiment, if Figure 3 and Figure 4As shown, the above-mentioned driving mechanism includes: an opening and closing driving sleeve 13, and the drug applying part 1 is arranged in the inner cavity of the opening and closing driving sleeve 13; the opening and closing driving sleeve 13 and the drug applying part 1 are relatively displaced to enable the drug applying part 1 to achieve folding and opening actions; in the open state, the elastic bracket 12 opens and closely fits the human tissue under the action of its own elastic force; in the folded state, the elastic bracket 12 is compressed in the opening and closing driving sleeve 13.

[0091] When the medication part 1 is in the open state, the opening and closing driving sleeve 13 and the medication part 1 move relative to each other in one direction, the medication part 1 gradually breaks away from the restraint of the opening and closing driving sleeve 13, and the medication part 1 opens to an appropriate position under the action of its own elastic restoring force; when the medication part 1 is in the folded state, the opening and closing driving sleeve 13 and the medication part 1 move relative to each other in the other direction, and the opening and closing driving sleeve 13 is close to the top of the medication part 1, so that the medication head can be inserted into the biological body.

[0092] In this embodiment, the elastic support 12 is a nickel-titanium alloy mesh; a diaphragm 14 is provided on the outer surface of the elastic support 12; the diaphragm 14 is used to prevent the medicine from entering the elastic support 12. The elastic support 12 is fixedly arranged on the medicine compressing conical cavity 2, and the medicine compressing bag 3 is a flexible membrane with an outer peripheral edge fixedly attached to the elastic support 12 and the medicine compressing conical cavity 2. The flexible membrane can be deformed according to the patient's diseased position, so that the medicine compressing head for applying medicine The part 1 of the medicine compressing head is more closely attached to the patient's diseased position, ensuring uniform application of the medicine.

[0093] In this embodiment, in order to facilitate the operation of medical workers, the opening and folding actions of the elastic support 12 are realized. The medical worker drives the opening and closing driving sleeve 13 to telescopically move relative to the medicine application conical cavity 2; when the opening and closing driving sleeve 13 is driven to move away from the medicine application direction, the elastic support 12 gradually opens; when the opening and closing driving sleeve 13 is driven to move toward the medicine application direction, the elastic support 12 gradually folds.

[0094] <Method Example>

[0095] like Figures 1 to 4 As shown:

[0096] A method for preparing a deep channel applicator head, comprising:

[0097] Step 1: prepare a deep channel applicator head including an applicator portion 1 and a driving mechanism; wherein the applicator conical cavity 2 is in an elastic cone shape, and is driven to extend and retract and drive the applicator portion 1 to extend into and out of human tissue; the applicator bag 3 is a deformable flexible material, and has a folded state and an open state. When folded, the instrument delivery radius of the deep channel applicator head is reduced, and when opened, the applicator portion 1 is opened to an appropriate position and closely fits human tissue;

[0098] The second step: mixing and stirring the drug component ingredients to a uniform mixture, wherein the drug component ingredients include 5-aminolevulinic acid or 5-aminolevulinic acid, glycerol and carbomer;

[0099] The third step: heating the fatty acid glyceride into a liquid solution;

[0100] Step 4: adding the mixture obtained in step 2 to the liquid solution obtained in step 3, and stirring until the mixture reaches a uniform state to prepare a photosensitizer gel solution;

[0101] Step 5: Open the application part 1 of the deep channel applicator obtained in the first step, and insert it into the photosensitizer gel solution obtained in the fourth step, so that a layer of photosensitizer gel solution is coated on the surface of the application part 1;

[0102] Step 6: Take out the application part 1 coated with a layer of photosensitizer gel liquid, and cool the photosensitizer gel liquid into a solid photosensitizer coating; then, return the application part 1 to the folded state through the driving mechanism to complete the photosensitizer pre-coating work.

[0103] In addition, it should be noted that, unless otherwise specified, the terms "first", "second", "third", etc. in the specification are only used to distinguish the various components, elements, steps, etc. in the specification, and are not used to indicate the logical relationship or sequential relationship between the various components, elements, steps, etc.

[0104] It is to be understood that, although the present invention has been disclosed as a preferred embodiment, the above embodiment is not intended to limit the present invention. For any person skilled in the art, without departing from the scope of the technical solution of the present invention, the technical content disclosed above can be used to make many possible changes and modifications to the technical solution of the present invention, or modified into equivalent embodiments of equivalent changes. Therefore, any simple modification, equivalent change and modification made to the above embodiments according to the technical essence of the present invention without departing from the content of the technical solution of the present invention still falls within the scope of protection of the technical solution of the present invention.

Claims

1. A deep channel applicator for a living body, characterized in that: include: A drug application part (1), the drug application part (1) is pre-coated with a drug and is used to apply the drug to a target part of a living body; The medicine application part (1) comprises: a medicine application conical cavity (2) and a medicine application bag (3); the medicine application conical cavity (2) is made of elastic material, and is in the shape of an elastic cone, and is driven to extend and retract, and drives the medicine application part (1) to extend into and out of human tissue; the medicine application bag (3) is made of deformable flexible material, and is arranged at the outer periphery of the medicine application conical cavity (2), and the medicine application bag (3) has a folded state and an opened state. When folded, the instrument delivery radius of the deep channel medicine application head is reduced, and when opened, the medicine application part (1) is opened to an appropriate position and closely fits human tissue; A driving mechanism is connected to the medicine dispensing portion (1) in a transmission manner and is used to drive the medicine dispensing portion (1) to switch between the folded state and the opened state.

2. The deep channel applicator for a living body according to claim 1, characterized in that: Also includes: The support assembly (4) comprises: a support member (5) and an outer sleeve (6) sleeved on the outside of the support member (5); the support member (5) and the outer sleeve (6) are slidably connected; the drug application part (1) is arranged at the end position of the support assembly (4); The driving mechanism comprises: An opening and closing assembly (7) comprises: an outer connecting rod (8) and an inner connecting rod (9); the inner connecting rod (9) is hingedly fixed to a support member fixing portion (10) of the support member (5) near the head; the outer connecting rod (8) is hingedly fixed to an outer sleeve fixing portion (11) at the head end of the outer sleeve (6); and the opening and closing assembly (7) is used to support the drug application portion (1) to apply drugs; the outer sleeve (6) and the support member (5) are relatively displaced to achieve the folding and opening action of the opening and closing assembly (7).

3. The deep channel applicator for a living body according to claim 2, characterized in that: The medicine application conical cavity (2) of the medicine application part (1) is arranged at the end position of the outer sleeve (6) of the opening and closing component (7); the medicine application bag (3) of the medicine application part (1) is fixed on the outer connecting rod (8) and the inner connecting rod (9) and is arranged toward the direction of human tissue; When the opening and closing assembly (7) is in the open state, the outer sleeve (6) and the support member (5) are mutually moved in one direction, and the inner connecting rod (9) and the outer connecting rod (8) are opened in a coordinated manner to prop the drug application portion (1) to an appropriate position for drug application; when the opening and closing assembly (7) is in the folded state, the outer sleeve (6) and the support member (5) are mutually moved in another direction, and the inner connecting rod (9) and the outer connecting rod (8) are linked and close to the opening and closing assembly (7), so that the deep channel applicator head can be inserted into the biological body.

4. The deep channel applicator for a living body according to claim 3, characterized in that: The outer sleeve (6) is driven to slide on the support member (5); when the outer sleeve (6) is driven to move toward a direction close to the medication application, the opening and closing assembly (7) gradually opens; when the outer sleeve (6) is driven to move away from the medication application direction, the opening and closing assembly (7) gradually folds.

5. The deep channel applicator for a living body according to claim 1, characterized in that: The medicine application part (1) further comprises: an elastic support (12) disposed on the medicine application conical cavity (2); the elastic support (12) wraps the medicine application conical cavity (2); The driving mechanism comprises: an opening and closing driving sleeve (13), the medicine applying part (1) being arranged in the inner cavity of the opening and closing driving sleeve (13); the opening and closing driving sleeve (13) and the medicine applying part (1) are relatively displaced so that the medicine applying part (1) can achieve folding and opening actions; in the open state, the elastic support (12) is opened and closely fits human tissue under the action of its own elastic force; in the folded state, the elastic support (12) is compressed in the opening and closing driving sleeve (13).

6. The deep channel applicator for a living body according to claim 5, characterized in that: The outer periphery of the elastic support (12) is closely connected to the inner wall of the opening and closing driving sleeve (13), so that the medicine applying part (1) is fixed in position within the opening and closing driving sleeve (13). When the medication application part (1) is in an open state, the opening and closing driving sleeve (13) and the medication application part (1) are mutually moved in one direction, the medication application part (1) gradually breaks away from the restraint of the opening and closing driving sleeve (13), and the medication application part (1) is opened to a proper position under the action of its own elastic restoring force; when the medication application part (1) is in a folded state, the opening and closing driving sleeve (13) and the medication application part (1) are mutually moved in another direction, the opening and closing driving sleeve (13) is close to the top end of the medication application part (1), so that the medication application head can be inserted into the biological body.

7. The deep channel applicator for a living body according to claim 5, characterized in that: The elastic support (12) is a nickel-titanium alloy mesh; The outer surface of the elastic support (12) is provided with a diaphragm (14); the diaphragm (14) is used to prevent medicine from entering the elastic support (12).

8. The deep channel applicator for a living body according to claim 5, characterized in that: The opening and closing driving sleeve (13) is driven to telescopically move relative to the medicine application conical cavity (2); when the opening and closing driving sleeve (13) is driven to move away from the medicine application direction, the elastic bracket (12) gradually opens; when the opening and closing driving sleeve (13) is driven to move toward the medicine application direction, the elastic bracket (12) gradually folds.

9. The deep channel applicator for a living body according to any one of claims 5 to 8, characterized in that: The elastic support (12) is fixedly arranged on the compress conical cavity (2), and the compress bag (3) is a flexible membrane with its outer periphery fixedly arranged on the elastic support (12) and the compress conical cavity (2).

10. A method for preparing a deep channel applicator for a living body according to any one of claims 1 to 9, characterized in that: include: The first step is to prepare a deep channel applicator head including a drug application part (1) and a driving mechanism; wherein the drug application conical cavity (2) is in the shape of an elastic cone, and is driven to extend and retract and drive the drug application part (1) to extend into and out of human tissue; the drug application bag (3) is a deformable flexible material, and has a folded state and an open state. When folded, the instrument delivery radius of the deep channel applicator head is reduced, and when opened, the drug application part (1) is opened to an appropriate position and closely fits human tissue; The second step: mixing and stirring the drug component ingredients to form a uniform mixture, wherein the drug component ingredients include 5-aminolevulinic acid or 5-aminolevulinic acid, glycerol and carbomer; The third step: heating the fatty acid glyceride into a liquid solution; Step 4: adding the mixture obtained in step 2 to the liquid solution obtained in step 3, and stirring until the mixture reaches a uniform state to prepare a photosensitizer gel solution; Step 5: Open the application part (1) of the deep channel applicator obtained in the first step and insert it into the photosensitizer gel solution obtained in the fourth step, so that a layer of photosensitizer gel solution is coated on the surface of the application part (1); Step 6: Take out the application part (1) with a layer of photosensitizer gel liquid coated on the surface, and cool the photosensitizer gel liquid into a solid photosensitizer coating; then, return the application part (1) to the folded state through the driving mechanism to complete the photosensitizer pre-coating work.

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