Microparticle preparation system and process

Abstract

The invention provides a particle preparation system and process, and relates to the technical field of particle preparation. The spraying device is connected with an outlet of the fluid conveying pipeline; the reaction device is arranged on a spraying path of the spraying device; the fluid charging structure is arranged on the fluid conveying pipeline, and the fluid charging structure can charge the fluid to generate charged fluid; and the deflection field is arranged between the spraying device and the reaction device, and the deflection field can disperse the charged fluid and then convey the dispersed charged fluid to the reaction device. A liquid flow column can be generated through the spraying device, and when the liquid flow column is sprayed to a deflection field, fluid molecules attached with charges in the liquid flow column can generate fluid uncertainty active dispersion under the action of charge repulsive force; and the fluid molecules can be further deflected and dispersed by utilizing the electromagnetic force action of the deflection field so as to form tiny liquid drops, and then the tiny liquid drops fall into the reaction device to generate particles.

Description

Technical Field

[0001] The present invention relates to the technical field of particle preparation, and in particular to a particle preparation system and process. Background Art

[0002] Particles can be formed by encapsulating solids, liquids or gases in tiny and sealed capsules. Particles can mask odors and colors, change the form of substances, isolate sensitive components, reduce toxicity, prolong the storage time of volatile substances, and delay the release of capsule materials. In particular, in the field of food technology, there is an important demand for food particles in order to achieve the distribution and dispersion of materials, the stabilization of active substances, and the improvement of taste and texture.

[0003] In the prior art, in order to better prepare microparticles, the water-soluble atomizing nozzle and the lipophilic solution atomizing nozzle are respectively connected to a high-voltage electrostatic generator, so that the water-soluble atomizing nozzle sprays hydrophilic droplets with positive charge, and the lipophilic solution atomizing nozzle sprays lipophilic droplets with negative charge. In the electrostatic field, the positively charged hydrophilic droplets and the negatively charged lipophilic droplets can move relative to each other under the action of the electric field force, so that the hydrophilic droplets and the lipophilic droplets merge to form microparticle particles. Since the water-soluble atomizing nozzle and the lipophilic solution atomizing nozzle need to spray positively charged hydrophilic droplets and negatively charged lipophilic droplets respectively, the distribution between the hydrophilic droplets and the lipophilic droplets is not uniform enough, resulting in some positively charged hydrophilic droplets and some negatively charged lipophilic droplets being far apart and unevenly distributed, resulting in the inability of the hydrophilic droplets and the lipophilic droplets of this part to automatically merge under the action of the electric field force. Summary of the invention

[0004] In order to overcome the above-mentioned defects of the prior art, the technical problem to be solved by the embodiments of the present invention is to provide a particle preparation system and process for actively dispersing the liquid flow column to form more uniform tiny droplets and fall into the reaction solution to generate particles.

[0005] The above-mentioned object of the present invention can be achieved by adopting the following technical scheme. The present invention provides a microparticle preparation system, comprising:

[0006] Fluid delivery pipelines;

[0007] an injection device connected to the outlet of the fluid delivery pipeline;

[0008] A reaction device, arranged on the injection path of the injection device;

[0009] A fluid charging structure, disposed on the fluid delivery pipeline, the fluid charging structure can charge the fluid to generate a charged fluid;

[0010] and a deflection field, which is arranged between the injection device and the reaction device, and the deflection field can disperse the charged fluid and then transport it to the reaction device.

[0011] In a preferred embodiment of the present invention, the particle preparation system further comprises an oscillating mechanism, and the oscillating mechanism is drivably connected to the injection device.

[0012] In a preferred embodiment of the present invention, the oscillation mechanism includes an ultrasonic oscillation device and a rigid conductive component, and the ultrasonic oscillation device is connected to the injection device through the rigid conductive component.

[0013] In a preferred embodiment of the present invention, the particle preparation system further comprises a discharge structure, the reaction device can accommodate a reaction solution, and the discharge structure can be electrically connected to the reaction solution.

[0014] In a preferred embodiment of the present invention, the discharge structure includes a grounding wire, and the grounding wire can be electrically connected to the reaction solution.

[0015] In a preferred embodiment of the present invention, the reaction device comprises a liquid droplet receiving container, and the liquid droplet receiving container is arranged on the spraying path of the spraying device.

[0016] In a preferred embodiment of the present invention, the reaction device further comprises a stirring mechanism disposed in the droplet receiving container.

[0017] In a preferred embodiment of the present invention, the injection device comprises a micro-tube nozzle, and the inner diameter of the micro-tube nozzle is 0.01mm-10mm.

[0018] In a preferred embodiment of the present invention, the inner diameter of the micro-tube nozzle is 0.04 mm-0.9 mm.

[0019] In a preferred embodiment of the present invention, the fluid charging structure includes a conductor embedded in the fluid conveying pipeline, and the conductor can charge the fluid to generate the charged fluid.

[0020] In a preferred embodiment of the present invention, the electrical conductor comprises a metal pipe section disposed on the fluid conveying pipeline.

[0021] In a preferred embodiment of the present invention, the fluid charging structure further comprises a current generator or a voltage transformer, and the current generator or the voltage transformer is electrically connected to the conductor.

[0022] In a preferred embodiment of the present invention, the particle preparation system further comprises a fluid storage container, and the fluid storage container is connected to the inlet of the fluid delivery pipeline.

[0023] In a preferred embodiment of the present invention, the fluid storage container is provided with an air pressure regulating device or an injection pump, and the air pressure regulating device or the injection pump can deliver the fluid in the fluid storage container to the fluid delivery pipeline at a first flow rate.

[0024] In a preferred embodiment of the present invention, the fluid storage container and the fluid delivery pipeline are insulated.

[0025] In a preferred embodiment of the present invention, the particle preparation system further comprises an electromagnetic generating device, which is capable of generating the deflection field, and the deflection field is controllably disposed between the injection device and the reaction device.

[0026] In a preferred embodiment of the present invention, the deflection field is the earth's magnetic field, and the injection path is arranged in the earth's magnetic field along a first direction.

[0027] In a preferred embodiment of the present invention, the particle preparation system also includes an electrostatic field capacitor plate, which can generate a deflection electric field. The deflection electric field is controllably arranged between the injection device and the reaction device, and the deflection field can be replaced by the deflection electric field.

[0028] The present invention also provides a microparticle preparation process, comprising:

[0029] Charging the first reaction solution so that molecules of the first reaction solution are attached with a single polarity charge;

[0030] Spraying the first reaction solution at a first flow rate to form a liquid flow column;

[0031] Allowing the liquid flow column to enter a preset deflection field, and utilizing the deflection field to disperse the liquid flow column to form tiny droplets;

[0032] Allowing the tiny droplets to fall into a second reaction solution to react and generate microparticles;

[0033] The second reaction solution and / or the particles are discharged.

[0034] The technical solution of the present invention has the following significant beneficial effects:

[0035] When the particle preparation system of the present invention is used, the first reaction solution can be transported through the fluid delivery pipeline, and the fluid charging structure can charge the first reaction solution in the fluid delivery pipeline, so that the molecules of the first reaction solution are all attached with a single polarity charge, and then the first reaction solution with the attached charge is sprayed out at a first flow rate through the spray device to form a liquid column, and the liquid column enters the preset deflection field. The deflection field and the charge repulsion between the fluid molecules with the attached charge work together to disperse the liquid column into tiny droplets. The tiny droplets can fall into the second reaction solution to react and generate particles, and then the second reaction solution is discharged to eliminate the charge on the particles.

[0036] In the present invention, when the liquid column is sprayed to the deflection field, the fluid molecules with attached charges in the liquid column will be actively dispersed under the action of the charge repulsion, and the electromagnetic force of the deflection field can further deflect the fluid molecules and disperse them, thereby generating tiny droplets. Due to the influence of the charge repulsion, the dispersed tiny droplets will not re-agglomerate and fuse in the air, and have a better dispersion effect. BRIEF DESCRIPTION OF THE DRAWINGS

[0037] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following briefly introduces the drawings required for use in the description of the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0038] The accompanying drawings described herein are only for explanation purposes and are not intended to limit the scope of the present invention in any way. In addition, the shapes and proportional dimensions of the various components in the figures are only schematic, used to help understand the present invention, and are not specifically limited to the shapes and proportional dimensions of the various components of the present invention. Those skilled in the art can select various possible shapes and proportional dimensions to implement the present invention according to the teachings of the present invention.

[0039] Figure 1 A schematic diagram of the structure of the microparticle preparation system of the present invention;

[0040] Figure 2 A front view of the liquid column dispersing in the deflection field in the present invention;

[0041] Figure 3 It is an enlarged schematic diagram of the dispersion of the liquid column in the deflection field in the present invention;

[0042] Figure 4 A schematic top view of the liquid droplet receiving container of the present invention receiving tiny liquid droplets;

[0043] Figure 5 The figure is a schematic diagram of an installation structure of the electrostatic field capacitor plate described in the present invention.

[0044] Reference numerals of the above drawings:

[0045] 1. Fluid delivery pipeline;

[0046] 2. Spray device; 21. Micro-tube nozzle;

[0047] 3. Reaction device; 31. Droplet receiving container;

[0048] 4. Fluid charging structure; 41. Conductor; 42. Current generator; 43. Voltage conversion device;

[0049] 5. Deflection field; 51. Electrostatic field capacitor plate;

[0050] 6. Discharge structure; 61. Ground wire;

[0051] 7. Fluid storage container;

[0052] 8. Oscillation mechanism; 81. Ultrasonic oscillation device; 82. Rigid conducting component;

[0053] 9. Stirring mechanism. DETAILED DESCRIPTION

[0054] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0055] According to the Plateau-Rayleigh fluid instability principle, the already extremely unstable liquid column fluid will continue to split into smaller droplets under the action of a series of external forces such as mechanical force, electromagnetic force, gravity and air resistance, and when each split droplet carries the same charge, it will continue to move away from each other to prevent re-agglomeration, and finally scatter in the reaction container below, thereby achieving the purpose of batch production of tiny core material droplets.

[0056] Please refer to Figure 1As shown, an embodiment of the present invention provides a particle preparation system, which includes: a fluid delivery pipeline 1; an injection device 2, connected to the outlet of the fluid delivery pipeline 1; a reaction device 3, arranged on the injection path of the injection device 2; a fluid charging structure 4, arranged on the fluid delivery pipeline 1, the fluid charging structure 4 can charge the fluid to generate a charged fluid; and a deflection field 5, arranged between the injection device 2 and the reaction device 3, the deflection field 5 can disperse the charged fluid and then transport it to the reaction device 3.

[0057] On the whole, when the particle preparation system is used, the first reaction solution can be transported through the fluid delivery pipeline 1, and the fluid charging structure 4 can charge the first reaction solution in the fluid delivery pipeline 1, so that the fluid molecules of the first reaction solution are all attached with a single polarity charge, and then the first reaction solution with the attached charge is sprayed out at a first flow rate through the spray device 2 to form a liquid column, and the liquid column enters the preset deflection field 5. The charge repulsion between the deflection field 5 and the fluid molecules with the attached charge works together to disperse the liquid column into tiny droplets. The tiny droplets can fall into the second reaction solution in the reaction device 3 to react to generate particles, and then the second reaction solution is discharged to eliminate the charge on the particles. The electrical mutual repulsion effect of the tiny droplets prevents the tiny droplets from condensing and fusing again in the air, thereby improving the average particle size stability of the microparticles.

[0058] The first reaction solution is a core material solution, and the second reaction solution is a wall material solution. Designers can adjust the specific components of the core material solution and the wall material solution according to usage requirements, and no specific restrictions are made here.

[0059] In the present invention, when the liquid column is sprayed to the deflection field 5, the fluid molecules with attached charges in the liquid column will be actively dispersed under the action of the charge repulsion, and the electromagnetic force of the deflection field 5 can further deflect the fluid molecules and disperse them, thereby generating tiny droplets. Due to the influence of the charge repulsion, the dispersed tiny droplets will not re-agglomerate and fuse in the air, and have a better dispersion effect.

[0060] In an embodiment of the present invention, the particle preparation system further comprises an oscillating mechanism 8 , which is drivably connected to the spraying device 2 .

[0061] In a specific embodiment, the oscillation mechanism 8 includes an ultrasonic oscillation device 81 and a rigid conductive component 82, and the ultrasonic oscillation device 81 is connected to the injection device 2 through the rigid conductive component 82. Preferably, the rigid conductive component 82 is a rigid conductive rod, and the conductive rod is connected to the nozzle of the injection device 2.

[0062] The ultrasonic oscillation device 81 can be used to apply high-frequency mechanical oscillations to the nozzle of the injection device 2. In particular, a rigid conduction rod can be used to directly conduct ultrasonic waves to the injection device 2, thereby synchronously applying the shock wave to the core solution column in the injection device 2, thereby loosening the binding force between the liquid molecules in the core solution column and making it easier to produce a droplet dispersion reaction.

[0063] Furthermore, the oscillation effect of the ultrasonic oscillation device 81 increases the fluidity of the unstable core material solution, and the oscillation effect of the ultrasonic oscillation device 81 can also reduce the risk of clogging of the nozzle of the injection device 2.

[0064] In other specific embodiments, the oscillation mechanism 8 may also be configured as a mechanical oscillation device, which is connected to the injection device 2 via a rigid conduction component 82 .

[0065] Of course, designers can also adjust the specific structure of the oscillation mechanism 8 according to usage requirements, and no specific restrictions are made here.

[0066] When the charged tiny droplets fall into the second reaction solution in the reaction device 3 for reaction, the charges in the tiny droplets also enter the second reaction solution in the reaction device 3, so that the second reaction solution is in a charged state. In order to obtain uncharged particles, the second reaction solution needs to be discharged to remove the charges on the second reaction solution and the particles.

[0067] In an embodiment of the present invention, the particle preparation system further comprises a discharge structure 6, the reaction device 3 can contain a reaction solution, and the discharge structure 6 can be electrically connected to the reaction solution. The reaction solution in the reaction device 3 is a second reaction solution.

[0068] By electrically connecting the discharge structure 6 to the reaction solution in the reaction device 3, the discharge structure 6 can reduce or eliminate the charge in the reaction solution, thereby obtaining uncharged particles. In addition, by continuously releasing the charge in the reaction solution, the charge is prevented from accumulating in the reaction solution, thereby improving the safety of use.

[0069] Specifically, the discharge structure 6 includes a grounding wire 61, which can be electrically connected to the reaction solution. One end of the grounding wire 61 is connected to the reaction solution, and the other end of the grounding wire 61 is connected to the ground, so that the charge in the reaction solution can be quickly released, which has a better use effect. In addition, the structure of the grounding wire 61 is simple and reliable, which reduces the manufacturing cost.

[0070] In an embodiment of the present invention, the reaction device 3 includes a liquid droplet receiving container 31 , and the liquid droplet receiving container 31 is disposed on the spraying path of the spraying device 2 .

[0071] Specifically, the droplet receiving container 31 has an opening. The opening is horizontally arranged below the spray device 2, and the falling tiny droplets can be received through the opening. The designer can adjust the size of the opening and the height interval between the opening and the spray device 2 according to the use requirements, and no specific restrictions are made here.

[0072] The height distance between the highest point of the droplet receiving container 31 and the lowest point of the spraying device 2 should not be too close to prevent high-voltage arc breakdown. The specific height is not limited here.

[0073] When the tiny droplets come into contact with the wall material solution in the reaction device 3, a curing reaction will occur to form embedded microparticles. During the entire reaction process, the wall material solution should maintain rapid flow to promote uniform distribution of the effective concentration in the wall material solution. The rapid flow of the wall material solution can also prevent problems such as stacking and agglomeration of the microparticles.

[0074] In order to speed up the flow rate of the wall material solution, in an embodiment of the present invention, the reaction device 3 further includes a stirring mechanism 9 disposed in the droplet receiving container 31. The stirring mechanism 9 can stir the solution in the droplet receiving container 31 so that the wall material solution can maintain a fast flow.

[0075] In a specific embodiment, the stirring mechanism 9 is a stirring paddle disposed in the droplet receiving container 31. In addition, the stirring paddle can be drivably connected to the driving motor.

[0076] In other specific embodiments, designers can adjust the specific structure of the stirring mechanism 9 according to usage requirements, and no specific limitation is made here.

[0077] In an embodiment of the present invention, the injection device 2 includes a micro-tube nozzle 21. The charged core material solution can be ejected through the micro-tube nozzle 21 under a certain pressure. The micro-tube nozzle 21 can be a conventional spray nozzle or a nozzle of other structures, and is not specifically limited here. Preferably, the inner diameter of the micro-tube nozzle 21 is 0.01 mm-10 mm.

[0078] A liquid column can be ejected through the microtube nozzle 21. The charged fluid molecules in the liquid column will be dispersed in an uncertain manner under the action of the charge repulsion, and the electromagnetic force of the deflection field 5 can further deflect and disperse the fluid molecules, thereby generating tiny droplets.

[0079] The present invention can realize the active dispersion process of turning liquid into tiny droplets by using the micro-tube nozzle 21. The active dispersion process is not a spray process and does not require any spray structure. Compared with the spray structure, the micro-tube nozzle 21 has a simple and reliable structure and is not easily blocked by impurities.

[0080] Furthermore, during the use of the micro-tube nozzle 21 , the dispersion degree of the micro-droplets can be adjusted by controlling the injection flow rate of the micro-tube nozzle 21 and the inner diameter of the micro-tube nozzle 21 , which is more convenient for control.

[0081] Since the inner diameter of the micro-tube nozzle 21 affects the state of the micro-droplets after the liquid column diffuses, and the charge strength attached to the fluid molecules also affects the state of the micro-droplets after the liquid column diffuses, when the micro-tube nozzle 21 remains unchanged, the particle size of the micro-droplets can be reduced by increasing the charge strength attached to the fluid molecules. Alternatively, when the charge strength attached to the fluid molecules remains unchanged, the particle size of the micro-droplets can be reduced by reducing the inner diameter of the micro-tube nozzle 21.

[0082] Similarly, the particle size of the micro-droplets can be increased by reducing the charge strength attached to the fluid molecules or increasing the inner diameter of the micro-tube nozzle 21. Therefore, the designer can control the particle size of the micro-droplets by reasonably adjusting the inner diameter of the micro-tube nozzle 21 and the charge strength attached to the fluid molecules.

[0083] Designers can adjust the inner diameter of the microtube nozzle 21 according to usage needs. For example, the inner diameter of the microtube nozzle 21 can be set to about 0.01 mm, or the inner diameter of the microtube nozzle 21 can be set to about 1 mm, or the inner diameter of the microtube nozzle 21 can be set to about 10 mm. No specific restrictions are made here.

[0084] In a preferred embodiment of the present invention, the inner diameter of the microtube nozzle 21 is 0.04mm-0.9mm. The microtube nozzle 21 is set as a flat-head microtube nozzle 21. By controlling the inner diameter of the microtube nozzle 21 between 0.04mm-0.9mm, when the output flow rate of the microtube nozzle 21 is stable, the liquid flow column can be output from the microtube nozzle 21 within a distance of 0.2mm-1.0mm without obvious dispersion, thereby generating a more stable direct liquid flow column. Among them, the smaller the inner diameter of the microtube nozzle 21, the smaller the average particle size of the microparticles prepared and the better the stability.

[0085] Designers can adjust the inner diameter of the microtube nozzle 21 according to usage needs. For example, the inner diameter of the microtube nozzle 21 can be set to 0.04 mm, or the inner diameter of the microtube nozzle 21 can be set to 0.51 mm, or the inner diameter of the microtube nozzle 21 can be set to 0.9 mm. No specific restrictions are made here.

[0086] In an embodiment of the present invention, the fluid charging structure 4 includes a conductor 41 embedded in the fluid delivery pipeline 1, and the conductor 41 can charge the fluid to generate a charged fluid. The fluid is a first reaction solution.

[0087] By embedding the conductor 41 in the fluid delivery pipeline 1 , the conductor 41 can be in direct contact with the first reaction solution, so that the conductor 41 can charge the first reaction solution, so that the fluid molecules of the first reaction solution are all attached with a single polarity charge.

[0088] In a specific embodiment, the conductor 41 includes a metal pipe section disposed on the fluid delivery pipeline 1. Designers can adjust the inner diameter and length of the metal pipe section according to usage requirements, and no specific restrictions are imposed herein.

[0089] Furthermore, the fluid charging structure 4 further includes a current generator 42, and the current generator 42 is electrically connected to the conductor 41. The current generator 42 can generate direct current, and the conductor 41 transfers the direct current to the first reaction solution, thereby charging the first reaction solution.

[0090] The designer can adjust the voltage of the DC power according to the use requirements, for example, the voltage can be controlled between 3kV and 20kV, and no specific limitation is made here. In addition, by increasing the voltage, the conductor 41 can charge the fluid with higher viscosity.

[0091] In another specific embodiment, the fluid charging structure 4 further includes a voltage transformer 43 , and the voltage transformer 43 is electrically connected to the conductor 41 .

[0092] By adjusting the voltage intensity, the charge intensity attached to the fluid molecules can be affected. When the voltage is higher, the diffusion effect of the tiny droplets is more significant.

[0093] In an embodiment of the present invention, the particle preparation system further comprises a fluid storage container 7 , and the fluid storage container 7 is connected to the inlet of the fluid delivery pipeline 1 .

[0094] The first reaction solution can be stored in the fluid storage container 7, which is connected to the inlet of the fluid delivery pipeline 1. During the production of microparticles, the first reaction solution can be continuously supplied to the fluid delivery pipeline 1 by using the fluid storage container 7. The fluid storage container 7 needs to be capable of providing a relatively constant feeding pressure to more stably deliver the first reaction solution.

[0095] The first reaction solution is a core material solution. In addition, the core material solution component needs to contain electrolytes, such as sodium chloride, sodium alginate, etc., and the electrolyte content and the required charging intensity show a certain inverse relationship, that is, the lower the electrolyte content in the core material component, the higher the voltage needs to be passed to charge the core material solution to achieve similar microparticle production effects, and the closer the charging site is to the end of the system, the better the dispersion effect.

[0096] In a specific embodiment, the fluid storage container 7 is provided with an air pressure regulating device, and the air pressure regulating device can deliver the fluid in the fluid storage container 7 to the fluid delivery pipeline 1 at a first flow rate.

[0097] The air pressure regulating device can stably pressurize the fluid in the fluid storage container 7 into the fluid delivery pipeline 1, making the flow rate in the fluid delivery pipeline 1 more stable and controllable. In addition, the air pressure regulating device can eliminate the pulse effect produced by a conventional pump, thereby reducing the flow rate fluctuation problem in the fluid delivery pipeline 1 and improving the production stability of the particles.

[0098] In another specific embodiment, a syringe pump is provided on the fluid storage container 7, and the syringe pump can deliver the fluid in the fluid storage container 7 to the fluid delivery pipeline 1 at a first flow rate. Preferably, the syringe pump is a high-precision syringe pump.

[0099] By using an air pressure regulating device or a syringe pump, flow fluctuations in the fluid delivery pipeline 1 can be reduced. When the output flow of the microtube nozzle 21 is stable, the liquid column can be output from the microtube nozzle 21 within a distance of 0.2mm-1.0mm without obvious dispersion, thereby generating a more stable direct liquid column.

[0100] Designers can adjust the flow rate in the fluid delivery pipeline 1 according to factors such as the electrolyte content and viscosity of the first reaction solution, and no specific restrictions are imposed herein.

[0101] In the embodiment of the present invention, the fluid storage container 7 and the fluid delivery pipeline 1 are insulated. By making the fluid storage container 7 and the fluid delivery pipeline 1 insulated, the charge attached to the fluid molecules will not be lost due to contact with other grounded conductors, thereby ensuring the strength of the charge attached to the fluid molecules.

[0102] Specifically, non-conductive materials such as glass, rubber or plastic are provided on the contact surfaces of the fluid storage container 7 and the fluid delivery pipeline 1 with the first reaction solution.

[0103] In an embodiment of the present invention, the particle preparation system further includes an electromagnetic generating device, which can generate a deflection field 5, and the deflection field 5 is controllably arranged between the injection device 2 and the reaction device 3. Designers can adjust the setting direction and deflection field strength of the deflection field 5 according to the dispersion requirements of the liquid flow column, and no specific restrictions are made here.

[0104] In another specific embodiment, the deflection field 5 is the earth's magnetic field, and the injection path is arranged in the earth's magnetic field along the first direction. By using the earth's magnetic field instead of the electromagnetic generating device, the manufacturing cost is reduced and it is more convenient to use. The designer can adjust the first direction according to the dispersion requirements of the liquid column, and no specific limitation is made here.

[0105] In other embodiments, Figure 5 In the illustrated embodiment, the particle preparation system further comprises an electrostatic field capacitor plate 51, which can generate a deflection electric field. The deflection electric field is controllably arranged between the injection device 2 and the reaction device 3, and the deflection field 5 can be replaced by the deflection electric field.

[0106] The deflection electric field can be in any horizontal direction. The liquid column of the core material solution ejected from the microtube nozzle 21 immediately enters the deflection electric field. The liquid column is gradually dispersed into tiny core material droplets by the force of the deflection electric field. If the target core material droplets are small and the attached charge intensity is large, the earth's magnetic field can be directly used to obtain a similar effect. In addition, the highest point of the deflection electric field should be 5mm-20mm away from the lowest point of the microtube nozzle 21, and the top view of the microtube nozzle 21 should be set in the middle of the two electrostatic field capacitor plates 51.

[0107] The electrostatic field capacitor plate 51 can replace the electromagnetic generating device, and the electrostatic field capacitor plate 51 is used to generate an electric field to disperse the liquid column. The designer can controllably adjust the setting direction and strength of the electric field according to the dispersion requirements of the liquid column, so that the charged liquid column fluctuates or deflects in multiple directions on the injection path, and no specific restrictions are made here.

[0108] In an embodiment of the present invention, a microparticle preparation process is also provided, comprising:

[0109] Step 100: charging the first reaction solution so that the molecules of the first reaction solution are attached with a single polarity charge.

[0110] Step 101: Spray a first reaction solution at a first flow rate to form a liquid flow column.

[0111] Step 102: Figure 2 and Figure 3 In the embodiment shown, the liquid flow column is made to enter a preset deflection field 5, and the deflection field 5 is used to disperse the liquid flow column to form tiny droplets.

[0112] Step 103: Figure 4 In the embodiment shown, the tiny droplets are dropped into the second reaction solution to react and generate microparticles.

[0113] Step 104: discharging the second reaction solution and / or the particles.

[0114] Specifically, the first reaction solution in the fluid storage container 7 is input into the fluid delivery pipeline 1 at a set flow rate, and the first reaction solution is delivered to the injection device 2 via the fluid delivery pipeline 1 .

[0115] When the first reaction solution is transported in the fluid transport pipeline 1 , the first reaction solution in the fluid transport pipeline 1 is charged by the fluid charging structure 4 , so that the fluid molecules of the first reaction solution are all attached with a single polarity charge.

[0116] Then, the first reaction solution with electric charges is sprayed out at a first flow rate through the spray device 2 to form a liquid flow column, and the liquid flow column enters the preset deflection field 5.

[0117] The deflection field 5 and the charge repulsion between the charged fluid molecules work together to disperse the liquid column into tiny droplets. The tiny droplets can fall into the second reaction solution to react and generate particles, and then the second reaction solution is discharged to eliminate the charge on the particles.

[0118] All articles and references disclosed, including patent applications and publications, are incorporated herein by reference for various purposes. The term "consisting essentially of ... " describing a combination should include determined elements, ingredients, parts or steps and other elements, ingredients, parts or steps that do not substantially affect the basic novel features of the combination. The use of the terms "comprising" or "including" to describe the combination of elements, ingredients, parts or steps here also contemplates the implementation method consisting essentially of these elements, ingredients, parts or steps. Here, by using the term "may", it is intended to illustrate that any attribute described that "may" includes is optional. Multiple elements, ingredients, parts or steps can be provided by a single integrated element, ingredient, part or step. Alternatively, a single integrated element, ingredient, part or step can be divided into separate multiple elements, ingredients, parts or steps. The disclosure "one" or "one" used to describe an element, ingredient, part or step is not said to exclude other elements, ingredients, parts or steps.

[0119] Each embodiment in this specification is described in a progressive manner, and each embodiment focuses on the differences from other embodiments. The same and similar parts between the embodiments can be referred to each other. The above embodiments are only for illustrating the technical concept and features of the present invention. The purpose is to enable people familiar with this technology to understand the content of the present invention and implement it accordingly, and it cannot be used to limit the scope of protection of the present invention. Any equivalent changes or modifications made according to the spirit of the present invention should be covered within the scope of protection of the present invention.

Claims

1. A microparticle preparation system, characterized in that: include: Fluid delivery pipelines; an injection device connected to the outlet of the fluid delivery pipeline; A reaction device, arranged on the injection path of the injection device; A fluid charging structure, disposed on the fluid delivery pipeline, the fluid charging structure can charge the fluid to generate a charged fluid; and a deflection field, which is arranged between the injection device and the reaction device, and the deflection field can disperse the charged fluid and then transport it to the reaction device.

2. The microparticle preparation system according to claim 1, characterized in that: The particle preparation system further comprises an oscillating mechanism, which is drivably connected to the injection device.

3. The microparticle preparation system according to claim 2, characterized in that: The oscillation mechanism includes an ultrasonic oscillation device and a rigid conductive component, and the ultrasonic oscillation device is connected to the injection device through the rigid conductive component.

4. The microparticle preparation system according to claim 1, characterized in that: The particle preparation system further includes a discharge structure, the reaction device can contain a reaction solution, and the discharge structure can be electrically connected to the reaction solution.

5. The microparticle preparation system according to claim 4, characterized in that: The discharge structure includes a grounding wire, and the grounding wire can be electrically connected to the reaction solution.

6. The microparticle preparation system according to claim 4, characterized in that: The reaction device comprises a liquid droplet receiving container, and the liquid droplet receiving container is arranged on the spraying path of the spraying device.

7. The microparticle preparation system according to claim 6, characterized in that: The reaction device further comprises a stirring mechanism arranged in the liquid drop receiving container.

8. The microparticle preparation system according to claim 1, characterized in that: The injection device comprises a micro-tube nozzle, and the inner diameter of the micro-tube nozzle is 0.04mm-0.9mm.

9. The microparticle preparation system according to claim 1, characterized in that: The fluid charging structure includes a conductor embedded in the fluid conveying pipeline, and the conductor can charge the fluid to generate the charged fluid.

10. The microparticle preparation system according to claim 9, characterized in that: The electrical conductor comprises a metal pipe section arranged on the fluid conveying pipeline.

11. The microparticle preparation system according to claim 9, characterized in that: The fluid charging structure further comprises a current generator or a voltage transformation device, and the current generator or the voltage transformation device is electrically connected to the conductor.

12. The microparticle preparation system according to claim 1, characterized in that: The particle preparation system further comprises a fluid storage container, which is connected to the inlet of the fluid delivery pipeline.

13. The microparticle preparation system according to claim 12, characterized in that: The fluid storage container is provided with an air pressure regulating device or an injection pump, and the air pressure regulating device or the injection pump can deliver the fluid in the fluid storage container to the fluid delivery pipeline at a first flow rate.

14. The microparticle preparation system according to claim 13, characterized in that: The fluid storage container and the fluid delivery pipeline are insulated from each other.

15. The microparticle preparation system according to claim 1, characterized in that: The particle preparation system further comprises an electromagnetic generating device, which is capable of generating the deflection field. The deflection field is controllably arranged between the injection device and the reaction device.

16. The microparticle preparation system according to claim 1, characterized in that: The deflection field is the earth's magnetic field, and the injection path is arranged in the earth's magnetic field along a first direction.

17. The microparticle preparation system according to claim 1, characterized in that: The particle preparation system further comprises an electrostatic field capacitor plate, which can generate a deflection electric field. The deflection electric field is controllably arranged between the injection device and the reaction device, and the deflection field can be replaced by the deflection electric field.

18. A process for preparing microparticles, characterized in that: include: Charging the first reaction solution so that molecules of the first reaction solution are attached with a single polarity charge; Spraying the first reaction solution at a first flow rate to form a liquid flow column; Allowing the liquid flow column to enter a preset deflection field, and utilizing the deflection field to disperse the liquid flow column to form tiny droplets; Allowing the tiny droplets to fall into a second reaction solution to react and generate microparticles; The second reaction solution and / or the particles are discharged.

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