Cryogenic vial access detection device

By designing the freezing storage tube access detection device, using components such as lever units, signal sensing units and cylinders, the difficulty of freezing storage tube positioning and sampling in existing test tube boxes is solved, and fast and accurate freezing storage tube management is achieved, and experimental efficiency and safety are improved.

CN119500305APending Publication Date: 2025-02-25ZHONGKE MEILING CRYOGENICS CO LTD
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202411917014.X
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-24
Publication Date
2025-02-25

AI Technical Summary

Technical Problem

The existing test tube boxes lack effective positioning devices in the management of frozen storage tubes, which makes it difficult to quickly locate and sample the frozen storage tubes, which easily damage or contaminate the labels, affecting the efficiency and accuracy of the experiment.

Method used

A freezing storage tube access detection device is designed, including a code scanning gun, a test tube box, a storage base and a detection roof. Through components such as lever units, signal sensing units and cylinders, the accurate insertion, ejection and positioning of the freezing storage tube is achieved.

Benefits of technology

The device can quickly and accurately locate and remove frozen storage tubes, reduce manual operation time, improve experimental efficiency, and reduce the risk of frozen storage tube damage and contamination.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN119500305A_ABST
    Figure CN119500305A_ABST
Patent Text Reader

Abstract

The invention relates to the technical field of test tube boxes, in particular to a cryopreservation tube storing and taking detection device which comprises a code scanning gun and further comprises a test tube box, the test tube box comprises a box body provided with an insertion hole and a packaging bottom plate installed at the bottom of the box body, an installation cavity is formed between the box body and the packaging bottom plate, and a lever unit is installed in the installation cavity; the storage pedestal comprises a bearing bin and a power source mounted in the bearing bin; a plurality of signal sensing units are mounted at the bottom of the detection top plate; through the test tube box provided with the lever unit, whether a cryopreservation tube is effectively inserted or not can be detected after the cryopreservation tube is inserted, and meanwhile, whether the cryopreservation tube needing to be taken out is effectively ejected or not can be detected in cooperation with an arranged power source; the test tube box can be quickly positioned and clamped by the arrangement of the object placing pedestal, and the signal sensing unit can detect whether the cryopreservation tubes are effectively ejected out or taken out or not; the cryogenic vial access positioning detection function can be realized on the whole, and the position information of the corresponding cryogenic vial can be accurately and effectively acquired.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The invention relates to the technical field of test tube boxes, and in particular to a freezing tube storage and access detection device. Background Art

[0002] In many fields such as biomedical research, clinical testing, and cell therapy, cryotubes are needed to freeze biological samples at low temperatures to maintain the activity and biological properties of the samples. Multiple cryotubes are stored in a test tube box.

[0003] With the continuous expansion of the scale of biological sample banks and the increasing number of experimental samples, the orderly management and precise positioning of test tubes in test tube boxes have become important issues that need to be urgently addressed. At present, conventional test tube boxes lack effective positioning devices during use, and can only rely on label identification to record the information of test tubes. Sampling requires repeated picking, which is time-consuming, and the labels are easily damaged or contaminated, making them difficult to identify, increasing the difficulty of quickly picking up the corresponding cryopreserved tubes. Some complex experiments or clinical applications require rapid screening and extraction of specific batches or types of samples. For example, in emergency cell therapy applications, quickly locating the required cell sample tubes is crucial to the treatment of patients, and traditional test tube boxes are difficult to achieve this.

[0004] In summary, we consider designing a device that can detect and locate the storage position of each cryotube on a test tube box so that the corresponding cryotube sample can be accurately and effectively selected; in view of this, we propose a cryotube storage and retrieval detection device. Summary of the invention

[0005] The purpose of the present invention is to solve the deficiencies mentioned in the above background technology and provide a cryotube access detection device.

[0006] In order to solve the above technical problems, the present invention adopts the following technical solutions:

[0007] A cryotube access detection device, comprising a barcode scanner for inputting cryotube information, and further comprising:

[0008] A test tube box, comprising a box body provided with a plurality of jacks, and a packaging bottom plate installed at the bottom of the box body, a mounting cavity is provided between the box body and the packaging bottom plate, a plurality of lever units corresponding to the positions of the jacks are installed in the mounting cavity, and the lever units are used to detect the insertion or ejection status of the cryotubes;

[0009] The storage stand comprises a carrying bin for carrying the test tube box, and a power source installed in the carrying bin corresponding to the position of the jack, the power source being used to push the cryotube upward;

[0010] A detection top plate has a bottom with a plurality of signal sensing units corresponding to the positions of the jacks installed thereon, and the signal sensing units are used to detect the positions of the cryopreservation tubes.

[0011] Preferably, the packaging bottom plate is provided with a plurality of top holes which are arranged coaxially with the jacks;

[0012] The packaging bottom plate is provided with side protrusions for packaging the two ends of the installation cavity, and a shaft is installed between the side protrusions at the two ends.

[0013] .The freezing tube storage and retrieval detection device as described in claim 1 is characterized in that: the lever unit includes a baffle and a connecting plate connected by a rotating seat, a plurality of the lever units are rotatably mounted on the shaft through the rotating seat, and a hammer head is installed at the outer end of the connecting plate.

[0014] Preferably, the baffle and the connecting plate form an obtuse angle with the opening facing upwards;

[0015] The baffle is located at a position corresponding to the insertion hole. When the cryogenic tube is inserted into the insertion hole, the cryogenic tube drives the lever unit to rotate along the shaft by pressing down the baffle.

[0016] Preferably, a conductive metal sheet is provided on the bottom surface of the baffle, and a disconnecting electrode sheet corresponding to the position of the conductive metal sheet is provided on the packaging bottom plate;

[0017] When the conductive metal sheet contacts the circuit-breaking electrode sheet, an electrically connected closed loop is formed, and the plurality of lever units are electrically connected in parallel.

[0018] Preferably, a support plate is installed in the carrying bin, and a supporting cavity and a driving cavity are respectively provided on the upper and lower sides of the carrying bin;

[0019] The test tube box is inserted into the support cavity.

[0020] Preferably, the support plate is provided with through holes corresponding to the positions of the ejection holes one by one, and a plurality of cylinders for ejecting the cryotubes upward are installed in the driving cavity as a power source.

[0021] Preferably, a vertical support plate is installed on the bearing compartment, and the vertical support plate is detachably mounted on the detection top plate through a connecting block.

[0022] Preferably, the signal sensing unit adopts a proximity switch.

[0023] Compared with the prior art, the present invention has the following beneficial effects:

[0024] 1. The cryotube access detection device can detect whether the cryotube is effectively inserted after being inserted through the test tube box provided with a lever unit, and can also cooperate with the provided power source to detect whether the cryotube to be taken out is effectively ejected;

[0025] 2. The device is equipped with a storage stand that can quickly locate the card-mounted test tube box, and the signal sensor unit is equipped to detect whether the cryopreservation tube is effectively ejected or taken out;

[0026] 3. The device as a whole can realize the storage and retrieval positioning detection function of the cryopreservation tube, can accurately and effectively obtain the corresponding cryopreservation tube position information, facilitate the automatic ejection of the cryopreservation tube, and facilitate the sampling operation. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] The drawings constituting a part of the present application are used to provide a further understanding of the present invention. The exemplary embodiments of the present invention and their descriptions are used to explain the present invention and do not constitute an improper limitation of the present invention. In the drawings:

[0028] Figure 1 This is one of the overall structural schematic diagrams of the present invention;

[0029] Figure 2 This is the second schematic diagram of the overall structure of the present invention;

[0030] Figure 3 It is an exploded view of the overall structure of the present invention;

[0031] Figure 4 It is the installation relationship diagram of the freezing tube and the test tube box of the present invention;

[0032] Figure 5 This is an exploded view of the test tube box of the present invention;

[0033] Figure 6 This is one of the cutaway views of the test tube box of the present invention;

[0034] Figure 7 This is the second cross-sectional view of the test tube box of the present invention;

[0035] Figure 8 This is a schematic diagram of the installation of the lever unit inside the test tube box of the present invention;

[0036] Fig. 9 A side view showing the mounting relationship between the lever unit and the shaft rod of the present invention;

[0037] Fig.10 It is a schematic diagram of the installation relationship between the lever unit and the shaft rod of the present invention;

[0038] Fig.11 This is a schematic diagram of the storage stand of the present invention;

[0039] Fig.12 This is a cutaway view of the storage stand of the present invention;

[0040] Fig.13 This is a diagram showing the installation relationship between the detection top plate and the signal sensing unit of the present invention.

[0041] The meaning of each number in the figure is:

[0042] 1. Cryogenic tube;

[0043] 2. Test tube box; 21. Box body; 201. Socket; 202. Mounting cavity; 22. Package bottom plate; 221. Top hole; 222. Side protrusion; 23. Shaft; 24. Lever unit; 241. Baffle; 242. Connecting plate; 243. Rotating seat; 244. Hammer;

[0044] 3. Storage platform; 31. Carrying compartment; 32. Support plate; 321. Through hole; 33. Vertical support plate; 34. Connecting block; 35. Cylinder; 301. Support cavity; 302. Drive cavity;

[0045] 4. Detection top plate; 5. Barcode scanner; 6. Signal sensing unit. DETAILED DESCRIPTION

[0046] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all of the embodiments. In the absence of conflict, the embodiments in this application and the features in the embodiments can be combined with each other. Based on the embodiments in the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work belong to the scope of protection of the present invention.

[0047] See also Figure 1-Figure 13 The present invention describes the above technical solution in detail through the following embodiments:

[0048] The cryotube access detection device of this embodiment includes: Figure 2 The barcode scanner 5 shown in the figure, after using the cryotube 1 to take samples, a label will be attached to the tube body, and the label records the sample information, and the barcode scanner 5 quickly scans and enters the cryotube 1 information into the background system. This part belongs to the existing mature application technology, so it will not be explained in detail; it also includes:

[0049] Test tube box 2, such as Figure 4-Figure 10As shown in the structure, the test tube box 2 of this embodiment includes a box body 21 with a 6×10 specification plug hole 201, and a packaging bottom plate 22 installed at the bottom of the box body 21; the packaging bottom plate 22 is provided with a top hole 221 coaxially arranged corresponding to the plug hole 201, and the packaging bottom plate 22 is provided with side protrusions 222 at both ends of the packaging installation cavity 202, and a shaft 23 is installed between the side protrusions 222 at both ends; It should be noted that in order to accurately and effectively detect whether the cryopreservation tube 1 is effectively inserted into the plug hole 201 or is lifted up in the plug hole 201, the present embodiment is as follows Figure 8-Figure 10 In the structure shown, a mounting cavity 202 is provided between the box body 21 and the packaging bottom plate 22 , and a lever unit 24 corresponding to the position of the plug hole 201 is installed in the mounting cavity 202 .

[0050] Specifically, Fig. 9 As shown in the structure, in this embodiment, the lever unit 24 includes a baffle 241 and a connecting plate 242 connected by a rotating seat 243, and the rotating seat 243 is coaxially rotatably mounted on the shaft 23, as shown in FIG. Figure 8 and Fig. 9 In the structure shown, a hammer head 244 is installed at the outer end of the connecting plate 242, and an obtuse angle with the opening facing upward is formed between the baffle 241 and the connecting plate 242; that is, when the freezing tube 1 is not effectively inserted into the socket 201 at the corresponding position, the lever unit 24 will rotate along the shaft 23 as a whole due to the deadweight of the hammer head 244, and keep the baffle 241 in the state of tilting upward at the socket 201; conversely, when the freezing tube 1 is accurately and effectively inserted into the socket 201, the freezing tube 1 will press down the baffle 241, so that the lever unit 24 as a whole overcomes the deadweight of the hammer head 244, so that the hammer head 244 rotates along the shaft 23 and tilts up.

[0051] It should be explained that the lever unit 24 is provided to effectively monitor whether the cryopreservation tube 1 is effectively inserted or ejected; therefore, a signal corresponding to the action needs to be detected, and a signal source needs to be provided. In this embodiment, a conductive metal sheet is provided on the bottom surface of the baffle 241. Figure 8 and Fig. 9 In the horizontal compression state shown, a circuit-breaking electrode sheet corresponding to the conductive metal sheet is provided on the packaging bottom plate 22. The circuit-breaking electrode sheet is two disconnected conductive electrode sheets. When the conductive metal sheet and the two disconnected conductive electrode sheets are in contact, an electrically connected closed loop can be formed. In order to effectively detect the insertion information of the cryogenic tubes 1 at various positions, the structure of the multiple lever units 24 connected to the closed loop in this embodiment adopts parallel electrical connection, so that the information of whether each cryogenic tube 1 is inserted or lifted can be output independently.

[0052] In order to realize the automatic ejection of the specific cryopreservation tube 1, the present embodiment is provided with a storage stand 3, such as Figure 11-Figure 12The structure shown includes a carrying bin 31 for carrying a test tube box 2, a support plate 32 is installed in the carrying bin 31, and the carrying bin 31 is located on the upper and lower sides of the support plate 32, respectively, and a support cavity 301 and a drive cavity 302 are provided, and the test tube box 2 is inserted in the support cavity 301; a through hole 321 corresponding to the position of the top hole 221 is provided on the support plate 32, and a plurality of cylinders 35 are installed in the drive cavity 302. After the output shaft of the cylinder 35 is ejected, it will pass through the through hole 321 to eject the cryogenic tube 1 upward. At this time, the lever unit 24 will be reset under the action of the hammer head 244, and the local electrical connection will be disconnected. The corresponding cryogenic tube 1 is effectively ejected to detect and judge. To accurately eject the specific cryogenic tube 1, it is necessary to record the process of inserting the specific position after the barcode scanning gun 5 enters the information during sampling, so that it can be accurately ejected when the corresponding sample needs to be taken out.

[0053] In this embodiment, a vertical support plate 33 is installed on the carrier bin 31. The vertical support plate 33 is detachably installed with a detection top plate 4 through a connecting block 34. A proximity switch corresponding to the position of the jack 201 is installed at the bottom of the detection top plate 4. The proximity switch can sense whether there is a cryogenic tube 1 at the corresponding position, which is a judgment condition for the withdrawal of the output shaft of the cylinder 35. The distance signal changes after the cryogenic tube 1 is placed, lifted or removed, which can be used as a verification structure to judge whether the cryogenic tube 1 is effectively placed, ejected or removed, thereby providing accuracy guarantee. In this embodiment, the cylinder 35 adopts a MAL16×25 mini cylinder, and the proximity switch adopts a LJ18A3-8-Z / BX inductive proximity switch, which has low cost and compact structure.

[0054] The cryopreservation tube access detection device has the following working principle: first, according to the needs of batch sample preparation, an information label is attached to the cryopreservation tube 1 during sampling, and the information is entered through the barcode scanner 5 before being placed in the test tube box 2, and the device is inserted into the jack 201; after insertion, the lever unit 24 at the corresponding position is pressed down to form a closed loop to release an electrical signal to the background, and the position information of the cryopreservation tube 1 with the signal label is recorded and obtained at this time, and the above steps are repeated to complete the sample preparation and storage process;

[0055] During use, when it is necessary to take out a single cryogenic tube 1 sample, the background system starts the mini cylinder at the corresponding position to push out the cryogenic tube 1 in sequence according to the required sample. At this time, the lever unit 24 is disconnected, and the electrical signal is lost to verify whether the ejection action is effective; at this time, the inductive proximity switch detects that the cryogenic tube 1 is lifted up but not taken out. After it is taken out, the inductive proximity switch signal is lost and returns to normal; when it is necessary to take out multiple cryogenic tubes 1 samples in batches, multiple cryogenic tubes 1 can be lifted up at one time. In this embodiment, a signal light is installed at the socket 201 of the test tube box 2. When it is needed When taking out the corresponding cryogenic tube 1, the corresponding signal light flashes, and the bottom lever unit 24 is disconnected after the cryogenic tube 1 is taken out, and the inductive proximity switch is used to verify whether the corresponding cryogenic tube 1 is taken out correctly; when multiple cryogenic tubes 1 are taken out and used, they need to be reset and put into the corresponding socket 201 again, and the barcode scanning gun 5 reads the corresponding position information after scanning the code. At this time, the signal light at the corresponding position socket 201 flashes, which is convenient for quickly inserting the corresponding cryogenic tube 1 for storage. Other embodiments can be equipped with a voice broadcast to quickly broadcast whether the corresponding position is accurately placed;

[0056] Repeating the above steps can efficiently complete the storage and retrieval of cryogenic tubes, and can detect the storage and access information of cryogenic tubes in real time without the need to manually search for corresponding cryogenic tubes. It has high accuracy and efficiency, and is of great significance for the combination of batch detection and information equipment. The above system control part belongs to the application of existing control programs, so no further explanation will be given.

[0057] It should be noted that if the embodiments of the present invention involve directional indications (such as up, down, left, right, front, back, etc.), the directional indications are only used to explain the relative position relationship, movement status, etc. between the components in a certain specific posture. If the specific posture changes, the directional indication will also change accordingly.

[0058] In addition, if there are descriptions involving "first", "second", etc. in the embodiments of the present invention, the descriptions of "first", "second", etc. are only used for descriptive purposes and cannot be understood as indicating or implying their relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" or "second" may explicitly or implicitly include at least one of the features.

[0059] It will be apparent to those skilled in the art that the present invention is not limited to the details of the exemplary embodiments described above and that the present invention can be implemented in other specific forms without departing from the spirit or essential features of the present invention. Therefore, the embodiments should be considered exemplary and non-restrictive in all respects, and the scope of the present invention is defined by the appended claims rather than the above description, and it is intended that all changes falling within the meaning and scope of the equivalent elements of the claims be included in the present invention.

Claims

1. A cryotube access detection device, comprising a barcode scanner (5) for inputting information of a cryotube (1), characterized in that: Also includes: A test tube box (2) comprises a box body (21) provided with a plurality of insertion holes (201), and a packaging bottom plate (22) installed at the bottom of the box body (21), a mounting cavity (202) being provided between the box body (21) and the packaging bottom plate (22), a plurality of lever units (24) corresponding to the positions of the insertion holes (201) being installed in the mounting cavity (202), and the lever units (24) being used to detect the insertion or ejection status of the cryopreservation tube (1); The storage stand (3) comprises a carrying bin (31) for carrying the test tube box (2), and a power source installed in the carrying bin (31) and corresponding to the position of the insertion hole (201), the power source being used to push the cryotube (1) upwards; A detection top plate (4) is provided with a plurality of signal sensing units (6) corresponding one-to-one to the positions of the plug holes (201) at the bottom, and the signal sensing units (6) are used to detect the positions of the cryopreservation tubes (1).

2. The cryotube access detection device according to claim 1, characterized in that: The packaging bottom plate (22) is provided with a plurality of top holes (221) which are arranged coaxially with the insertion hole (201) and correspond to each other; The packaging bottom plate (22) is provided with side protrusions (222) for packaging the two ends of the installation cavity (202), and a shaft (23) is installed between the side protrusions (222) at the two ends.

3. The cryotube access detection device according to claim 2, characterized in that: The lever unit (24) comprises a baffle (241) and a connecting plate (242) connected via a rotating seat (243); a plurality of the lever units (24) are rotatably mounted on the shaft (23) via the rotating seat (243); and a hammer head (244) is mounted on the outer end of the connecting plate (242).

4. The cryotube access detection device according to claim 3, characterized in that: An obtuse angle with the opening facing upward is formed between the baffle plate (241) and the connecting plate (242); The baffle (241) is located at a position corresponding to the insertion hole (201). When the cryogenic tube (1) is inserted into the insertion hole (201), the cryogenic tube (1) drives the lever unit (24) to rotate along the shaft (23) by pressing down the baffle (241).

5. The cryotube access detection device according to claim 4, characterized in that: A conductive metal sheet is provided on the bottom surface of the baffle (241), and a disconnecting electrode sheet corresponding to the position of the conductive metal sheet is provided on the packaging bottom plate (22); When the conductive metal sheet and the disconnecting electrode sheet are in contact, an electrically connected closed loop is formed, and a plurality of the lever units (24) are electrically connected in parallel.

6. The cryotube access detection device according to claim 2, characterized in that: A support plate (32) is installed in the bearing bin (31), and a support cavity (301) and a driving cavity (302) are respectively provided on the upper and lower sides of the bearing bin (31) and the support plate (32); The test tube box (2) is inserted into the supporting cavity (301).

7. The cryotube access detection device according to claim 6, characterized in that: The support plate (32) is provided with through holes (321) corresponding to the positions of the ejection holes (221) one by one, and a plurality of cylinders (35) for ejecting the cryotube (1) upwards are installed in the driving chamber (302) as a power source.

8. The cryotube access detection device according to claim 7, characterized in that: A vertical support plate (33) is installed on the bearing bin (31), and the vertical support plate (33) is detachably mounted on the detection top plate (4) via a connecting block (34).

9. The cryotube access detection device according to claim 1, characterized in that: The signal sensing unit (6) adopts a proximity switch.