Compound washing preservative as well as preparation method and application thereof

Abstract

The invention discloses a compound washing preservative as well as a preparation method and application thereof, and the compound washing preservative comprises the following components or consists of the following components: a group: phenoxyethanol; group b: one or more of ethylhexylglycerin, benzethonium chloride, didecyl dimethyl ammonium chloride, benzoic acid, benzyl alcohol and dichlorobenzyl alcohol; and the group c comprises at least one or more of deionized water, ethylene glycol, propylene glycol and butanediol. The preservative composition provided by the invention has the characteristics of mildness, no irritation, moisture retention, no residue and environmental friendliness, the preservative effect is better than that of single use of phenoxyethanol under the condition of lower dosage, and the purposes of composite synergism, additive amount reduction and application cost control are achieved by exerting the respective characteristics of various preservatives.

Description

Technical Field

[0001] The invention relates to the technical field of antiseptics for washing products, in particular to a compound antiseptic for washing, a preparation method and application thereof. Background Art

[0002] Most detergents commonly used on the market have a neutral pH and are mostly used to clean clothes or items.

[0003] In a preservative for liquid detergents and a preparation method thereof with announcement number CN104322555A, the mass percentages of the components are: sodium nitrate 1%-3.5%; isothiazolinone 1%-3.5%; bropol 5%-15%; sodium dehydroacetate 5%-10%; the remainder is water; the sum of the mass percentages of the components is 100%. The invention also provides a preparation method for a preservative for liquid detergents, which compounds several active components with different antibacterial properties to form a new preservative, broadens its antibacterial range, increases antibacterial activity, and reduces the cost of preservation.

[0004] The preservative used in the above application includes sodium dehydroacetate, but the preservative in the application is used in detergents, which is relatively irritating and can easily damage the skin.

[0005] In a mild and non-irritating full food-grade detergent composition and its preparation method with announcement number CN111394192A, the application uses two food-grade surfactants, polyglycerol fatty acid esters and sucrose fatty acid esters, for compounding. The compounding system can produce a synergistic effect, which can effectively enhance the richness of detergent foam, reduce the critical micelle concentration, increase rinsability, reduce irritation, and enhance detergency.

[0006] The above applications are mostly used for cleaning clothes. During use, due to long-term storage, the detergent is easy to breed bacteria, resulting in the generation of odor.

[0007] In a method for inhibiting the growth of microorganisms in an anionic formulation with publication number CN1947505A, the application includes adding a mixture of the following substances having a synergistic effect into the anionic formulation: (a) a salt of benzethoxylammonium; and (b) at least one of the following substances: (i) dehydroacetic acid or a salt thereof; and (ii) salicylic acid or a salt thereof.

[0008] The above application has the problem that the amount of material blended is uncontrollable and the accuracy is relatively poor.

[0009] Currently, most preservatives used in detergents are isothiazolinone and its related derivatives. These ingredients are highly irritating and can easily cause adverse reactions in the human body if used for a long time. In addition, if a single ingredient is used for a long time, microorganisms can easily develop drug resistance. Therefore, complex and low-irritation preservatives are recommended.

[0010] In view of the above problems, we provide a compound washing preservative and its preparation method and application. Summary of the invention

[0011] The purpose of the present invention is to provide a compound washing preservative and a preparation method and application thereof, so as to solve the existing problems.

[0012] To achieve the above object, the present invention provides the following technical solutions:

[0013] A compound washing preservative comprises the following components, or is composed of the following components:

[0014] Group a:

[0015] Phenoxyethanol;

[0016] Group B:

[0017] One or more of ethylhexylglycerin, benzethonium chloride, didecyldimethylammonium chloride, benzoic acid, benzyl alcohol, and dichlorobenzyl alcohol;

[0018] Group C:

[0019] At least one or more of deionized water, ethylene glycol, propylene glycol, and butylene glycol.

[0020] Preferably, the component b is selected from ethylhexylglycerol, benzethonium chloride, didecyldimethylammonium chloride, benzoic acid, benzyl alcohol, dichlorobenzyl alcohol, and one or more thereof.

[0021] Preferably, the composition comprises, by weight percentage: 10-35% of component a, 20-60% of component b, and 15-75% of component c.

[0022] Preferably, the component b comprises, by weight percentage: 10-20% ethylhexylglycerol, 10-20% benzethonium chloride, 5-10% didecyldimethylammonium chloride, 10-20% benzoic acid, 10-20% benzyl alcohol, and 10-20% dichlorobenzyl alcohol.

[0023] A method for preparing a composite washing preservative comprises the following steps:

[0024] The a. phenoxyethanol, any one or more of the b components and any one of the c components are stirred and dissolved uniformly at 20-40° C. to obtain a composite preservative.

[0025] The invention discloses an application of a compound detergent preservative in detergent products.

[0026] A washing preservative, the washing product contains a preservative substance, and the preservative substance includes the above-mentioned preservative composition.

[0027] Preferably, the amount of the preservative composition in the washing agent is 0.1-0.4 wt %.

[0028] Compared with the prior art, the present invention has the following beneficial effects:

[0029] The preservative composition provided by the present invention avoids the use of isothiazolinone substances with high irritation, and has a better preservative effect than the single use of phenoxyethanol at a lower dosage. The synergistic effect of multiple ingredients is enhanced, so that the dosage of preservatives is reduced, the cost is reduced, and the irritation is greatly reduced. DETAILED DESCRIPTION

[0030] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments.

[0031] Embodiment 1:

[0032] According to the weight percentage, 82.5% of phenoxyethanol, 15% of component b, and 2.5% of deionized water are prepared; the component b is calculated according to the weight percentage: 10% of ethylhexylglycerin, 10% of benzethonium chloride, 20% of dehydroacetic acid, 20% of benzyl alcohol, 20% of dichlorobenzyl alcohol, and 20% of didecyldimethylammonium chloride.

[0033] Phenoxyethanol, component b and deionized water are stirred at 20-40° C. until they are completely dissolved, and then cooled to room temperature to finally prepare a preservative composition containing phenoxyethanol.

[0034] Embodiment 2:

[0035] According to weight percentage, 78.5% phenoxyethanol, 20% component b, and 2.5% propylene glycol are prepared; the component b contains 20% ethylhexylglycerol, 20% benzethonium chloride, 20% benzoic acid, 20% benzyl alcohol, 10% dichlorobenzyl alcohol, and 10% didecyldimethylammonium chloride according to weight percentage. Phenoxyethanol, component b, and propylene glycol are stirred at 20-40° C. until they are completely dissolved, and then cooled to room temperature to finally obtain a preservative composition containing phenoxyethanol.

[0036] Embodiment 3:

[0037] According to the weight percentage, 85% of phenoxyethanol, 10% of component b, and 5.0% of ethylene glycol are prepared; the component b is calculated according to the weight percentage: 30% of ethylhexylglycerin, 50% of benzethonium chloride, 5% of benzoic acid, 5% of benzyl alcohol, 5% of dichlorobenzyl alcohol, and 5% of didecyldimethylammonium chloride.

[0038] Phenoxyethanol, component b and ethylene glycol are stirred at 20-40° C. until they are completely dissolved, and then cooled to room temperature to finally prepare a preservative composition containing phenoxyethanol.

[0039] Embodiment 4:

[0040] According to the weight percentage, 80% phenoxyethanol, 15% component b, and 5.0% deionized water are prepared; the component b contains, according to the weight percentage, 10% ethylhexylglycerin, 10% benzethonium chloride, 30% benzoic acid, 10% benzyl alcohol, 20% dichlorobenzyl alcohol, and 20% didecyldimethylammonium chloride. Phenoxyethanol, component b, and deionized water are stirred at 20-40° C. until they are completely dissolved, and then cooled to room temperature to finally obtain a preservative composition containing phenoxyethanol.

[0041] Embodiment 5:

[0042] According to the weight percentage, 80% phenoxyethanol, 10% component b, and 10% ethylene glycol are prepared; the component b contains 5% ethylhexylglycerol, 5% benzethonium chloride, 20% benzoic acid, 25% benzyl alcohol, 25% dichlorobenzyl alcohol, and 20% didecyldimethylammonium chloride according to the weight percentage. Phenoxyethanol, component b, and ethylene glycol are stirred at 20-40° C. until they are completely dissolved, and then cooled to room temperature to finally obtain a preservative composition containing phenoxyethanol.

[0043] Embodiment 6:

[0044] According to the weight percentage, 75% phenoxyethanol, 15% component b, and 10% 1,2-propylene glycol are prepared; the component b is calculated according to the weight percentage: 10% ethylhexylglycerol, 5% benzethonium chloride, 15% benzoic acid, 30% benzyl alcohol, 20% dichlorobenzyl alcohol, and 20% didecyldimethylammonium chloride. Phenoxyethanol, component b, and 1,2-propylene glycol are stirred at 20-40° C. until they are completely dissolved, and then cooled to room temperature to finally prepare a preservative composition containing phenoxyethanol.

[0045] Embodiment 7:

[0046] According to weight percentage, 70% phenoxyethanol, 20% component b, and 10% deionized water are prepared; the component b contains 10% ethylhexylglycerol, 20% benzethonium chloride, 15% benzoic acid, 15% benzyl alcohol, 10% dichlorobenzyl alcohol, and 30% didecyldimethylammonium chloride according to weight percentage. Phenoxyethanol, component b, and deionized water are stirred at 20-40° C. until they are completely dissolved, and then cooled to room temperature to finally prepare a preservative composition containing phenoxyethanol.

[0047] Comparative case 1:

[0048] According to the weight percentage, 90% phenoxyethanol and 10% propylene glycol are prepared; the phenoxyethanol and propylene glycol are stirred at 20-40° C. until they are completely dissolved, and then cooled to room temperature to finally prepare a preservative containing phenoxyethanol.

[0049] Specific practical application case 1:

[0050] The preservative compositions obtained in Examples 1-7 and Comparative Example 1 were applied to detergents:

[0051] The preparation process of the detergent is as follows:

[0052] At 20-40℃, add the raw materials in the stirring pot in the order shown in the table below, and stir to dissolve evenly:

[0053]

[0054]

[0055] The above detergents were subjected to antiseptic tests:

[0056] The above detergent was divided into 8 parts on average, one blank detergent was not added with any preservative, the preservative composition prepared in the comparative case was added to 1 blank detergent, and then the preservative composition of the compounded Examples 1-7 was added to the other 7 blank detergents (corresponding to the numbers), and the following bacteria and molds were added to the above 8 detergent samples: Staphylococcus aureus (ATCC 6538), Pseudomonas aeruginosa ATCC9027, Aspergillus niger ATCC16404, Escherichia coli ATCC25922, Candida albicans ATCC10231, and the inoculation amount was 6.0×10 6 CFU / g or 3.0×10 6 CFU / g. The same amount of bacteria was inoculated into the samples on the 0th day, the 7th day, and the 14th day, and the residual bacteria in the samples were counted every 7 days. The data were compared to determine the antiseptic effect. The results are shown in Table 2:

[0057] Table 2

[0058]

[0059]

[0060]

[0061] It can be seen from Table 2 that the detergents prepared by using the preservative composition prepared by Examples 1-7 as the "9# preservative" component can reduce the number of bacteria and fungi to less than 10 cfu / ml within 7 days after inoculation of microorganisms on the 0th day, the 7th day, and the 14th day, while the detergents prepared by using the preservative prepared by the control sample as the preservative component cannot reduce the number of bacteria and fungi to less than 10 cfu / ml within 7 days. The total amount of preservatives added in Examples 1 to 7 is the same as that in the control example, but in terms of the preservative effect, Examples 1 to 7 are better than the control example, which means that the preservative composition used in the present invention has a better preservative effect than the single use of phenoxyethanol at a lower dosage.

[0062] In summary, the antiseptic composition provided by the present invention has a better anti-corrosion effect at a lower dosage than the single use of phenoxyethanol. Since the dosage of the preservative is very small, the irritation is reduced and it is suitable for use in various detergent formulations.

[0063] The above descriptions are merely embodiments of the present invention and are not intended to limit the patent scope of the present invention. Any equivalent transformations made using the contents of the present invention specification, or directly or indirectly applied in related technical fields, are also included in the patent protection scope of the present invention.

Claims

1. A composite washing preservative, characterized in that: Contains or consists of the following components: Group a: Phenoxyethanol; Group B: One or more of ethylhexylglycerin, benzethonium chloride, didecyldimethylammonium chloride, benzoic acid, benzyl alcohol, and dichlorobenzyl alcohol; Group C: At least one or more of deionized water, ethylene glycol, propylene glycol, and butylene glycol.

2. A composite washing preservative according to claim 1, characterized in that: The component b is selected from ethylhexylglycerin, benzethonium chloride, didecyldimethylammonium chloride, benzoic acid, benzyl alcohol, dichlorobenzyl alcohol, and one or more thereof.

3. A composite washing preservative according to claim 1, characterized in that: The composition comprises, by weight percentage, 60-85% of component a, 10-30% of component b and 5-10% of component c.

4. A composite washing preservative according to claim 1, characterized in that: The component b is calculated by weight percentage as follows: 10-20% of ethylhexylglycerol, 10-20% of benzethonium chloride, 10-20% of benzoic acid, 10-20% of benzyl alcohol, 10-20% of benzyl alcohol, and 10-20% of dichlorobenzyl alcohol.

5. A method for preparing a composite washing preservative according to any one of claims 1 to 3, characterized in that: The following steps are involved: First, the phenoxyethanol in component a is evenly divided into two parts, one part is mixed with any one or more of the components b, and stirred to dissolve at 45-55° C., and the other part is stirred and dissolved evenly with any one of the components c at room temperature. The two parts are mixed and stirred evenly to complete the preparation.

6. Use of the compound detergent preservative according to any one of claims 1 to 3 in detergent products.

7. A washing preservative, characterized in that: The cleaning product contains an antiseptic substance, and the antiseptic substance includes the preservative composition according to any one of claims 1-3.

8. The cleaning device according to claim 7, characterized in that: The amount of the preservative composition in the washing agent is 0.1-0.4 wt %.

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