Dilution container cleanliness quantitative judgment device and judgment method thereof

Abstract

The invention discloses a quantitative judgment device and method for the cleanliness degree of a dilution container. The judgment device comprises a cleaning mechanism, a first liquid injection mechanism, a second liquid injection mechanism, a liquid suction mechanism, a detection mechanism, a drying mechanism and a moving mechanism, the cleaning mechanism comprises a cleaning base, a first cleaning assembly and a second cleaning assembly, the first cleaning assembly and the second cleaning assembly are movably connected to the cleaning base, and the first cleaning assembly comprises a first cleaning needle and a first waste liquid needle; the second cleaning assembly comprises second cleaning needles and second waste liquid needles, the first liquid injection mechanism can communicate with the first cleaning needles so as to inject cleaning liquid into the first cleaning needles independently, and the second liquid injection mechanism can communicate with the second cleaning needles so as to inject purified water into the second cleaning needles independently; the liquid suction mechanism can suck waste liquid, the detection mechanism is used for detecting the conductivity, and the drying mechanism is used for drying the dilution container with the cleanliness meeting the requirement. The cleaning degree of the dilution container can be quantitatively judged.

Description

Technical Field

[0001] The present application relates to the field of medical devices and biological detection technology, and in particular to a device and method for quantitatively judging the cleanliness of a dilution container. Background Art

[0002] At present, in biological testing, fully automatic biochemical analyzers, specific protein analyzers, etc. are equipped with sample dilution functions in order to meet the requirements of completing multiple test functions with a small amount of human blood samples while improving the linear range of the test. The sample dilution multiple can reach 2 to 200 times. During dilution, the blood sample is added to a dilution container such as a dilution cup through the sample addition system, and then the diluent is added for dilution. The diluted blood is supplied to the machine for clinical testing. After the corresponding test is completed, the dilution container needs to be cleaned and reused. In the prior art, the dilution container only has a cleaning function, but it is impossible to quantitatively judge the cleanliness of the dilution container. If the cleaning is not in place, the residual ions in the dilution container will affect the subsequent clinical test results. The dilution container is also difficult to reuse, resulting in a waste of consumables. Summary of the invention

[0003] Based on this, it is necessary to provide a dilution container cleanliness quantitative judgment device. The dilution container cleanliness quantitative judgment device of the present invention can judge the cleanliness of the dilution container by reading the quantitative value in the dilution container, which is convenient for the reuse of the dilution container and will not affect the subsequent clinical test results.

[0004] An embodiment of the present application provides a device for quantitatively determining the cleanliness level of a dilution container.

[0005] A device for quantitatively judging the cleanliness of a dilution container comprises a cleaning mechanism, a first liquid injection mechanism, a second liquid injection mechanism, a liquid suction mechanism, a detection mechanism, a drying mechanism and a moving mechanism, wherein the cleaning mechanism comprises a cleaning base and a first cleaning component and at least one second cleaning component movably connected to the cleaning base, wherein the first cleaning component comprises a first cleaning needle and a first waste liquid needle, wherein the second cleaning component comprises a second cleaning needle and a second waste liquid needle, wherein the first liquid injection mechanism can communicate with the first cleaning needle to realize the injection of cleaning liquid into the first cleaning needle alone, and the second liquid injection mechanism can communicate with each second cleaning needle respectively to realize the injection of cleaning liquid into each second cleaning needle alone. Purified water is injected into the second cleaning needle, the liquid aspiration mechanism can be independently communicated with the first waste liquid needle and the second waste liquid needle to achieve the absorption of waste liquid through the first waste liquid needle or the second waste liquid needle, the detection mechanism is movably connected to the cleaning base to detect the conductivity of the liquid in the dilution container, the drying mechanism is movably connected to the cleaning base to dry the dilution container whose cleanliness meets the requirements, and the moving mechanism is connected to the cleaning base or the dilution container tray and drives it to move, so as to achieve the dilution container to transfer position between the first cleaning component, the second cleaning component, the detection mechanism, and the drying mechanism.

[0006] In some embodiments, the cleaning base has a plurality of workstations sequentially and spaced apart in the same direction, the spacing between adjacent workstations is not less than the width of a dilution container, and the first cleaning component, the plurality of the second cleaning components, the detection mechanism, and the drying mechanism are sequentially arranged in different workstations.

[0007] In some embodiments, the first liquid injection mechanism includes a cleaning liquid storage tank, a first cleaning pipeline and a first diaphragm pump, the cleaning liquid storage tank is connected to the first cleaning needle through the first cleaning pipeline, and the first diaphragm pump is installed in the first cleaning pipeline.

[0008] In some embodiments, the second injection mechanism includes a purified water storage tank, a second cleaning pipe, a second diaphragm pump and a control valve, the purified water storage tank is connected to the second cleaning needle through the second cleaning pipe, and the second diaphragm pump and the purified water storage tank are installed in the second cleaning pipe.

[0009] In some embodiments, the second injection mechanism also includes a cleaning sub-pipeline, each of the second cleaning needles is connected in parallel to the second cleaning pipe through the cleaning sub-pipeline, each of the cleaning sub-pipeline is provided with the control valve, and the second diaphragm pump is installed in the second cleaning pipe.

[0010] In some embodiments, the liquid aspiration mechanism includes a waste liquid storage box, a waste liquid pipe and a waste liquid pump, the waste liquid storage box is connected to the first waste liquid needle and each of the second waste liquid needles through the waste liquid pipe, and the waste liquid pump is arranged in the waste liquid pipe.

[0011] In some embodiments, the detection mechanism includes an electrode detection component, which includes parallel electrode plates arranged in parallel. The parallel electrode plates can be loaded with a sinusoidal voltage to obtain a current between the parallel electrode plates, and the conductivity is converted through Ohm's law.

[0012] In some embodiments, the drying mechanism includes a drying needle and a drying cleaning piece, the drying needle is communicated with the liquid suction mechanism to achieve adsorption and drying treatment of the dilution container, and the drying cleaning piece is used to brush and dry the dilution container.

[0013] In some embodiments, the dilution container cleanliness quantitative determination device further comprises a dilution container tray, on which a plurality of fixed grooves are arranged at intervals along the same direction, and the fixed grooves are used to accommodate the dilution containers to be cleaned, and the moving mechanism is connected to the dilution container tray and drives the dilution container tray to move, and the moving mechanism drives the dilution container tray to move each time by a distance equal to the width of one dilution container;

[0014] And / or, the dilution container cleanliness quantitative determination device further comprises a lifting drive component, wherein the lifting drive component is connected to the cleaning base to drive the cleaning base to move upward and downward;

[0015] And / or, the dilution container cleanliness quantitative determination device further comprises an alarm mechanism, which is electrically connected to the detection mechanism, and when the detection mechanism determines that the cleanliness of the dilution container does not meet the requirements according to the detection result, the alarm mechanism performs an alarm operation.

[0016] An embodiment of the present application also provides a method for quantitatively determining the cleanliness level of a dilution container.

[0017] A method for quantitatively judging the cleanliness of a dilution container, using the above-mentioned device for quantitatively judging the cleanliness of a dilution container, comprises the following steps:

[0018] Installing the dilution container to be cleaned on the dilution container tray so that the dilution container is located below the first cleaning component;

[0019] Control the cleaning base to descend until the first waste liquid needle of the first cleaning assembly abuts against the bottom surface of the dilution container and absorbs the residual waste liquid in the dilution container; control the first liquid injection mechanism to inject cleaning liquid into the dilution container through the first cleaning needle;

[0020] Control the moving mechanism to drive the dilution container tray to move one station, so that the dilution container is located below the Nth second cleaning component, N≥1, control the cleaning base to descend until the second waste liquid needle of the second cleaning component abuts against the bottom surface of the dilution container, control the liquid suction mechanism to suck the waste liquid in the dilution container through the second waste liquid needle, control the second liquid injection mechanism to inject purified water into the dilution container through the second cleaning needle, and repeat this step at least once;

[0021] Control the moving mechanism to drive the dilution container tray to move one station so that the dilution container is located below the detection mechanism, control the cleaning base to descend until the detection mechanism enters the dilution container, and control the detection mechanism to detect the conductivity of the purified water in the dilution container;

[0022] The conductivity is judged. When the conductivity is less than 1 μS / cm, it indicates that the cleanliness of the dilution container meets the requirements. The moving mechanism is controlled to drive the dilution container tray to move one station so that the dilution container is located below the drying mechanism. The drying mechanism is controlled to move into the dilution container to dry the dilution container. When the conductivity is greater than or equal to 1 μS / cm, it indicates that the cleanliness of the dilution container does not meet the requirements.

[0023] In some embodiments, the method for quantitatively determining the cleanliness level of the dilution container further comprises the following steps:

[0024] When the cleanliness of the dilution container does not meet the requirements, the moving mechanism is controlled to drive the dilution container tray to move in reverse, so that the dilution container is located below the first second cleaning component, the cleaning base is controlled to descend until the second waste liquid needle of the second cleaning component abuts against the bottom surface of the dilution container, the liquid suction mechanism is controlled to suck the waste liquid in the dilution container through the second waste liquid needle, and the second liquid injection mechanism is controlled to inject purified water into the dilution container through the second cleaning needle, and this step is repeated at least once;

[0025] The control detection mechanism performs the detection step again.

[0026] In some embodiments, the method for quantitatively determining the cleanliness level of the dilution container further comprises the following steps:

[0027] When the cleanliness level of the dilution container does not meet the requirements, the control alarm mechanism will sound an alarm.

[0028] The above-mentioned dilution container cleanliness quantitative judgment device can judge the cleanliness of the dilution container by reading the quantitative value in the dilution container, which is convenient for the reuse of the dilution container and will not affect the subsequent clinical test results.

[0029] The above-mentioned dilution container cleanliness quantitative judgment device detects the cleanliness of the dilution container in real time through the electrode detection component contained in the detection structure. The electrode detection component places two parallel electrode plates in the tested solution of the dilution container, applies a certain potential, usually a sine wave voltage, to both ends of the electrode plates, and then measures the current flowing between the electrode plates, converts it into conductivity through Ohm's law, and judges the conductivity data to quantitatively detect the cleanliness of the dilution container.

[0030] The above-mentioned dilution container cleanliness quantitative judgment device provides a reference for the user through the alarm function of the alarm mechanism to prevent the subsequent clinical results from being affected due to inadequate cleaning of the dilution container. The dilution container whose cleanliness does not meet the requirements can be cleaned again. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the following briefly introduces the drawings required for use in the description of the embodiments. Obviously, the drawings described below are only some embodiments of the present application, and those skilled in the art can obtain other drawings based on these drawings without creative work.

[0032] In order to more completely understand the present application and its beneficial effects, the following description will be given in conjunction with the accompanying drawings. In the following description, the same reference numerals represent the same parts.

[0033] FIG1 is a schematic diagram of a device for quantitatively determining the cleanliness level of a dilution container according to an embodiment of the present invention;

[0034] FIG. 2 is a schematic diagram of the detection structure of a device for quantitatively determining the cleanliness level of a dilution container according to an embodiment of the present invention.

[0035] Description of Reference Numerals

[0036] 10. Quantitative judgment device for cleanliness degree of dilution container; 100. Cleaning mechanism; 110. Cleaning base; 120. First cleaning component; 121. First cleaning needle; 122. First waste liquid needle; 130. Second cleaning component; 131. Second cleaning needle; 132. Second waste liquid needle; 200. First injection mechanism; 210. Cleaning liquid storage box; 220. First cleaning pipeline; 230. First diaphragm pump; 300. Second injection mechanism; 310. Purified water storage box; 320. Second cleaning pipeline; 330. Second diaphragm pump; 340. Control valve; 350. Cleaning sub-pipeline; 400. Suction mechanism; 410. Waste liquid storage box; 420. Waste liquid pipeline; 430. Waste liquid pump; 500. Detection mechanism; 510. Parallel electrode plates; 600. Drying mechanism; 700. Dilution container tray. DETAILED DESCRIPTION

[0037] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific embodiments of the present invention are described in detail below in conjunction with the accompanying drawings. In the following description, many specific details are set forth to facilitate a full understanding of the present invention. However, the present invention can be implemented in many other ways different from those described herein, and those skilled in the art can make similar improvements without violating the connotation of the present invention, so the present invention is not limited by the specific embodiments disclosed below.

[0038] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as limiting the present invention.

[0039] In the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements, unless otherwise clearly defined. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0040] In the present invention, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, a first feature being "above", "above" or "above" a second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. A first feature being "below", "below" or "below" a second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0041] In the description of the present invention, "several" means more than one, "many" means more than two, "greater than", "less than", "exceed", etc. are understood to exclude the number itself, and "above", "below", "within", etc. are understood to include the number itself. If there is a description of "first" or "second", it is only used for the purpose of distinguishing the technical features, and cannot be understood as indicating or implying the relative importance or implicitly indicating the number of the indicated technical features or implicitly indicating the order of the indicated technical features.

[0042] In this article, "optionally", "optional", "optional" means optional, that is, it means to be selected from any of the two parallel solutions of "yes" or "no". If there are multiple "optional" in a technical solution, unless otherwise specified and there is no contradiction or mutual restriction, each "optional" is independent. In this application, the descriptions such as "optionally contain" and "optionally include" mean "contain or not contain".

[0043] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as those commonly understood by those skilled in the art to which the present invention belongs. The terms used herein in the specification of the present invention are only for the purpose of describing specific embodiments and are not intended to limit the present invention. The term "and / or" used herein includes any and all combinations of one or more of the related listed items.

[0044] The embodiment of the present application provides a device for quantitatively judging the cleanliness of a dilution container to solve the problem that the dilution container in the prior art only has a cleaning function but cannot quantitatively judge the cleanliness of the dilution container, and that due to inadequate cleaning, the residual ions in the dilution container will affect the subsequent clinical test results, and the dilution container is difficult to reuse, resulting in waste of consumables. The device for quantitatively judging the cleanliness of a dilution container will be described below in conjunction with the accompanying drawings.

[0045] The dilution container cleanliness quantitative determination device 10 provided in the embodiment of the present application is exemplified as shown in FIG1 , which is a schematic diagram of the structure of the dilution container cleanliness quantitative determination device 10 provided in the embodiment of the present application. The dilution container cleanliness quantitative determination device 10 of the present application can be used in the fields of fully automatic biochemical analyzers, specific protein analyzers, and the like, and is specifically used for quantitative determination of the cleanliness of various dilution containers such as dilution cups, measuring cups, and the like.

[0046] In order to more clearly illustrate the structure of the device 10 for quantitatively determining the cleanliness level of a dilution container, the device 10 for quantitatively determining the cleanliness level of a dilution container will be introduced below with reference to the accompanying drawings.

[0047] For example, please refer to FIG. 1 , a device 10 for quantitatively judging the cleanliness of a dilution container includes a cleaning mechanism 100, a first liquid injection mechanism 200, a second liquid injection mechanism 300, a liquid suction mechanism 400, a detection mechanism 500, a drying mechanism 600, and a moving mechanism. The cleaning mechanism 100 includes a cleaning base 110, a first cleaning assembly 120 and at least one second cleaning assembly 130 movably connected to the cleaning base 110. The first cleaning assembly 120 includes a first cleaning needle 121 and a first waste liquid needle 122. The second cleaning assembly 130 includes a second cleaning needle 131 and a second waste liquid needle 132. The first liquid injection mechanism 200 can communicate with the first cleaning needle 121 to inject cleaning liquid into the first cleaning needle 121 separately. The second liquid injection mechanism 300 can communicate with each second cleaning needle 131 to inject purified water into each second cleaning needle 131 separately. The liquid suction mechanism 400 can be connected to the first waste liquid needle 122 and the second waste liquid needle 132 separately to achieve the suction of waste liquid through the first waste liquid needle 122 or the second waste liquid needle 132. The detection mechanism 500 is movably connected to the cleaning base 110 to detect the conductivity of the liquid in the dilution container. The drying mechanism 600 is movably connected to the cleaning base 110 to dry the dilution container whose cleanliness meets the requirements. The moving mechanism is connected to the cleaning base 110 or the dilution container tray 700 and drives it to move, so as to realize the dilution container to be transferred between the first cleaning component 120, the second cleaning component 130, the detection mechanism 500, and the drying mechanism 600.

[0048] In some embodiments, a plurality of stations are sequentially and spaced apart along the same direction on the cleaning base 110. The spacing between adjacent stations is not less than the width of a dilution container. The first cleaning assembly 120, the plurality of second cleaning assemblies 130, the detection mechanism 500, and the drying mechanism 600 are sequentially arranged in different stations.

[0049] In some embodiments, as shown in FIG1 , the first injection mechanism 200 includes a cleaning liquid storage tank 210, a first cleaning pipeline 220, and a first diaphragm pump 230. The cleaning liquid storage tank 210 is connected to the first cleaning needle 121 through the first cleaning pipeline 220, and the first diaphragm pump 230 is installed in the first cleaning pipeline 220. After the injection is completed, the first diaphragm pump 230 is turned off.

[0050] In some embodiments, as shown in FIG1 , the second injection mechanism 300 includes a purified water storage tank 310, a second cleaning pipeline 320, a second diaphragm pump 330, and a control valve 340. The purified water storage tank 310 is connected to the second cleaning needle 131 through the second cleaning pipeline 320, and the second diaphragm pump 330 and the purified water storage tank 310 are installed in the second cleaning pipeline 320.

[0051] In some embodiments, please refer to FIG. 1 , the second injection mechanism 300 further includes a cleaning sub-pipeline 350. Each second cleaning needle 131 is connected in parallel to the second cleaning pipe 320 through the cleaning sub-pipeline 350. A control valve 340 is provided on each cleaning sub-pipeline 350, and a second diaphragm pump 330 is installed on the second cleaning pipe 320. When the second injection mechanism 300 is injecting liquid, the second diaphragm pump 330 is controlled to open, and the control valve 340 on the cleaning sub-pipeline 350 connected to the corresponding second cleaning component 130 is controlled to open. After the injection is completed, the second diaphragm pump 330 and the control valve 340 are closed.

[0052] In some of these embodiments, the control valve may be a solenoid valve.

[0053] In some embodiments, as shown in FIG1 , the liquid aspiration mechanism 400 includes a waste liquid storage box 410, a waste liquid pipeline 420, and a waste liquid pump 430. The waste liquid storage box 410 is connected to the first waste liquid needle 122 and each second waste liquid needle 132 through the waste liquid pipeline 420, and the waste liquid pump 430 is disposed in the waste liquid pipeline 420. After the aspiration is completed, the waste liquid pump 430 is turned off.

[0054] In some embodiments, the detection mechanism 500 includes an electrode detection component. Preferably, the electrode detection component can be an electrode sensor.

[0055] Please refer to FIG. 1 and FIG. 2 , FIG. 2 is a schematic diagram of the detection structure of a dilution container cleanliness quantitative determination device 10 according to an embodiment of the present invention, wherein the electrode detection component includes parallel electrode plates 510 arranged in parallel. The parallel electrode plates 510 can be loaded with a sinusoidal voltage to obtain the current between the parallel electrode plates 510, and the conductivity is obtained by conversion through Ohm's law. The above-mentioned dilution container cleanliness quantitative determination device 10 detects the cleanliness in the dilution container in real time through the electrode detection component contained in the detection structure. The electrode detection component places two parallel electrode plates in the solution to be tested in the dilution container, applies a certain potential at both ends of the electrode plates, usually a sinusoidal voltage, and then measures the current flowing between the electrode plates, and obtains the conductivity by converting through Ohm's law. By judging the conductivity data, the cleanliness of the dilution container can be quantitatively detected.

[0056] In some embodiments, the drying mechanism 600 includes a drying needle and a drying cleaning member. The drying needle is connected to the liquid absorption mechanism 400 to realize adsorption drying treatment of the dilution container, and the drying cleaning member is used to brush and dry the dilution container. The drying needle and the drying cleaning member are not shown in the drawings. The drying needle can further absorb the residual purified water in the dilution container. The brushing of the auxiliary drying cleaning member can accelerate the drying of the dilution container. The dried dilution container is used for other tests.

[0057] In some of these embodiments, the dry cleaning member can be a dry brush.

[0058] In some embodiments, as shown in FIG. 1 , the dilution container cleanliness quantitative determination device 10 further includes a dilution container tray 700. The dilution container tray 700 is provided with a plurality of fixed grooves spaced apart in the same direction. The fixed grooves are used to accommodate the dilution containers to be cleaned. The moving mechanism is connected to the dilution container tray 700 and drives the dilution container tray 700 to move. The moving mechanism drives the dilution container tray 700 to move each time by a distance equal to the width of one dilution container.

[0059] In some of the embodiments, the moving mechanism may be a driving motor, a driving cylinder, etc.

[0060] In some embodiments, the dilution container cleanliness quantitative judgment device 10 also includes a lifting drive component. The lifting drive component is connected to the cleaning base 110 to drive the cleaning base 110 to move up and down. The lifting drive component is not shown in the drawings. The position where the lifting drive component drives the cleaning base 110 to descend is based on the length of the first cleaning needle 121. Each time the lifting drive component drives the cleaning base 110 to descend, the end of the first waste liquid needle 122 can be abutted to the bottom surface close to the dilution container, but not completely in contact with the bottom surface of the dilution container, so as to achieve smooth absorption of waste liquid. Preferably, the first waste liquid needle 122 and the second waste liquid needle 132 have the same length. More preferably, the first cleaning needle 121, the second cleaning needle 131, the first waste liquid needle 122, and the second waste liquid needle 132 have the same length.

[0061] In some embodiments, the dilution container cleanliness quantitative determination device 10 further includes an alarm mechanism. The alarm mechanism is electrically connected to the detection mechanism 500. When the detection mechanism 500 determines that the cleanliness of the dilution container does not meet the requirements according to the detection results, the alarm mechanism performs an alarm operation. The alarm mechanism is not shown in the drawings. The above-mentioned dilution container cleanliness quantitative determination device 10 provides a reference for the user through the alarm function of the alarm mechanism to prevent the dilution container from being inadequately cleaned and affecting the subsequent clinical results. The dilution container whose cleanliness does not meet the requirements can be cleaned again.

[0062] In some embodiments, the dilution container cleanliness quantitative judgment device 10 also includes a control mechanism. The above-mentioned cleaning mechanism 100, the first liquid injection mechanism 200, the second liquid injection mechanism 300, the liquid suction mechanism 400, the detection mechanism 500, the drying mechanism 600 and the moving mechanism are electrically connected to the control mechanism respectively. Specifically, the first diaphragm pump 230, the second diaphragm pump 330, the control valve 340, the waste liquid pump 430, the electrode detection component, the lifting drive component, and the alarm mechanism are electrically connected to the control mechanism respectively. The control mechanism is not shown in the accompanying drawings, wherein the control mechanism can be a PLC programmable logic controller. The control mechanism can set corresponding programs according to the action needs of the cleaning mechanism 100, the first liquid injection mechanism 200, the second liquid injection mechanism 300, the liquid suction mechanism 400, the detection mechanism 500, the drying mechanism 600 and the moving mechanism.

[0063] An embodiment of the present application also provides a method for quantitatively determining the cleanliness level of a dilution container.

[0064] In this article, unless otherwise stated, each reaction step may be carried out in the order described herein or may not be carried out in the order described herein. For example, other steps may be included between each reaction step, and the order of the reaction steps may also be appropriately swapped. This can be determined by the technician based on common knowledge and experience. Preferably, the reaction method herein is carried out sequentially.

[0065] A method for quantitatively determining the cleanliness of a dilution container, using the above-mentioned device 10 for quantitatively determining the cleanliness of a dilution container, comprises the following steps:

[0066] Install the dilution container to be cleaned on the dilution container tray 700 and place the dilution container below the first cleaning assembly 120;

[0067] Control the cleaning base 110 to descend until the first waste liquid needle 122 of the first cleaning assembly 120 abuts against the bottom surface of the dilution container and absorbs the residual waste liquid in the dilution container; control the first liquid injection mechanism 200 to inject cleaning liquid into the dilution container through the first cleaning needle 121;

[0068] Control the moving mechanism to drive the dilution container tray 700 to move one station, so that the dilution container is located below the Nth second cleaning assembly 130, N ≥ 1, control the cleaning base 110 to descend until the second waste liquid needle 132 of the second cleaning assembly 130 abuts against the bottom surface of the dilution container, control the liquid suction mechanism 400 to suck the waste liquid in the dilution container through the second waste liquid needle 132, control the second liquid injection mechanism 300 to inject purified water into the dilution container through the second cleaning needle 131, and repeat this step at least once;

[0069] Control the moving mechanism to drive the dilution container tray 700 to move one station so that the dilution container is located below the detection mechanism 500, control the cleaning base 110 to descend until the detection mechanism 500 enters the dilution container, and control the detection mechanism 500 to detect the conductivity of the purified water in the dilution container;

[0070] The conductivity is judged. When the conductivity is less than 1 μS / cm, it indicates that the cleanliness of the dilution container meets the requirements. The moving mechanism is controlled to drive the dilution container tray 700 to move one station so that the dilution container is located under the drying mechanism 600. The drying mechanism 600 is controlled to move into the dilution container to dry the dilution container. When the conductivity is ≥1 μS / cm, it indicates that the cleanliness of the dilution container does not meet the requirements.

[0071] In some embodiments, the method for quantitatively determining the cleanliness level of the dilution container further comprises the following steps:

[0072] When the cleanliness of the dilution container does not meet the requirements, the moving mechanism is controlled to drive the dilution container tray 700 to move in the reverse direction, so that the dilution container is located below the first second cleaning assembly 130, the cleaning base 110 is controlled to descend until the second waste liquid needle 132 of the second cleaning assembly 130 abuts against the bottom surface of the dilution container, the liquid suction mechanism 400 is controlled to suck the waste liquid in the dilution container through the second waste liquid needle 132, and the second liquid injection mechanism 300 is controlled to inject purified water into the dilution container through the second cleaning needle 131, and this step is repeated at least once;

[0073] The detection mechanism 500 is controlled to perform the detection step again.

[0074] In some embodiments, the method for quantitatively determining the cleanliness of the dilution container further includes the following steps: when the cleanliness of the dilution container does not meet the requirements, controlling the alarm mechanism to sound an alarm.

[0075] Example 1

[0076] This embodiment also provides a method for quantitatively determining the cleanliness level of a dilution container.

[0077] A method for quantitatively determining the cleanliness of a dilution container, using the above-mentioned device 10 for quantitatively determining the cleanliness of a dilution container, comprises the following steps:

[0078] S1 . sequentially install a plurality of dilution containers to be cleaned in the fixed grooves on the dilution container tray 700 , and place the first dilution container below the first cleaning assembly 120 .

[0079] S2. The control mechanism controls the lifting drive component to drive the cleaning base 110 to descend until the first waste liquid needle 122 of the first cleaning assembly 120 abuts against the bottom surface of the dilution container, and the control mechanism controls the waste liquid pump 430 to operate to absorb the residual waste liquid in the dilution container through the first waste liquid needle 122.

[0080] S3. The control mechanism controls the lifting drive component to drive the cleaning base 110 to reset to the first cleaning assembly 120 so that the first cleaning needle 121 moves to the upper part of the dilution container. The control mechanism controls the first diaphragm pump 230 on the first cleaning pipeline 220 to operate, and the first cleaning needle 121 pumps cleaning liquid from the cleaning liquid storage tank 210 into the dilution container.

[0081] S4. The control mechanism controls the moving mechanism to drive the dilution container tray 700 to move one station so that the dilution container is located below the first second cleaning component 130. The control mechanism controls the lifting and lowering driving component to drive the cleaning base 110 to descend until the second waste liquid needle 132 of the second cleaning component 130 abuts against the bottom surface of the dilution container. The control mechanism controls the waste liquid pump 430 to operate to absorb the waste liquid in the dilution container through the second waste liquid needle 132.

[0082] S5. The control mechanism controls the lifting drive component to drive the cleaning base 110 to reset to the second cleaning assembly 130 so that the second cleaning needle 131 moves to the upper part of the dilution container. The control mechanism controls the second diaphragm pump 330 on the second cleaning pipeline 320 to operate, and controls the corresponding control valve 340 to open, so that the purified water in the purified water storage tank 310 is input into the dilution container through the second cleaning needle 131 for cleaning of the purified water.

[0083] S6. The control mechanism controls the moving mechanism to drive the dilution container tray 700 to move one station so that the dilution container is below the second second cleaning assembly 130, and steps S4 and S5 are repeated.

[0084] S7, the control mechanism controls the moving mechanism to drive the dilution container tray 700 to move one station, so that the dilution container is located below the detection mechanism 500. The control mechanism controls the lifting and driving component to drive the cleaning base 110 to descend until the electrode detection component of the detection mechanism 500 enters the dilution container. The electrode detection component places two parallel electrode plates in the solution to be tested in the dilution container, applies a certain potential, usually a sine wave voltage, to both ends of the electrode plates, and then measures the current flowing between the electrode plates. The conductivity is converted by Ohm's law, and the conductivity data is judged to quantitatively detect the cleanliness of the dilution container. The control mechanism controls the lifting and driving component to drive the cleaning base 110 to reset.

[0085] S8. Determine the conductivity.

[0086] When the conductivity is less than 1 μS / cm, it indicates that the cleanliness of the dilution container meets the requirements: the control mechanism controls the moving mechanism to drive the dilution container tray 700 to move one station, so that the dilution container is located below the drying mechanism 600; the control mechanism controls the lifting and lowering driving component to drive the cleaning base 110 to descend, so that the drying needle and the drying cleaning member of the drying mechanism 600 move into the dilution container to dry the dilution container.

[0087] When the conductivity is ≥1μS / cm, it indicates that the cleanliness of the dilution container does not meet the requirements: the control mechanism controls the alarm mechanism to give an alarm to remind the operator.

[0088] S9. When the cleanliness of the first dilution container meets the requirements, the second dilution container is cleaned. Specifically, the control mechanism controls the moving mechanism to drive the dilution container tray 700 to move so that the second dilution container is located below the first cleaning assembly 120, and steps S2 to S8 are repeated.

[0089] Example 2

[0090] This embodiment also provides a method for quantitatively determining the cleanliness level of a dilution container.

[0091] A method for quantitatively determining the cleanliness of a dilution container, using the above-mentioned device 10 for quantitatively determining the cleanliness of a dilution container, comprises the following steps:

[0092] S1 . sequentially install a plurality of dilution containers to be cleaned in the fixed grooves on the dilution container tray 700 , and make the first dilution container be located below the first cleaning assembly 120 .

[0093] S2. The control mechanism controls the lifting drive component to drive the cleaning base 110 to descend until the first waste liquid needle 122 of the first cleaning assembly 120 abuts against the bottom surface of the dilution container, and the control mechanism controls the waste liquid pump 430 to operate to absorb the residual waste liquid in the dilution container through the first waste liquid needle 122.

[0094] S3. The control mechanism controls the lifting drive component to drive the cleaning base 110 to reset to the first cleaning assembly 120 so that the first cleaning needle 121 moves to the upper part of the dilution container. The control mechanism controls the first diaphragm pump 230 on the first cleaning pipeline 220 to operate, and the first cleaning needle 121 pumps cleaning liquid from the cleaning liquid storage tank 210 into the dilution container.

[0095] S4. The control mechanism controls the moving mechanism to drive the dilution container tray 700 to move one station so that the dilution container is located below the first second cleaning component 130. The control mechanism controls the lifting and lowering driving component to drive the cleaning base 110 to descend until the second waste liquid needle 132 of the second cleaning component 130 abuts against the bottom surface of the dilution container. The control mechanism controls the waste liquid pump 430 to operate to absorb the waste liquid in the dilution container through the second waste liquid needle 132.

[0096] S5. The control mechanism controls the lifting drive component to drive the cleaning base 110 to reset to the second cleaning assembly 130 so that the second cleaning needle 131 moves to the upper part of the dilution container. The control mechanism controls the second diaphragm pump 330 on the second cleaning pipeline 320 to operate, and controls the corresponding control valve 340 to open, so that the purified water in the purified water storage tank 310 is input into the dilution container through the second cleaning needle 131 for cleaning of the purified water.

[0097] S6. The control mechanism controls the moving mechanism to drive the dilution container tray 700 to move one station so that the dilution container is below the second second cleaning assembly 130, and steps S4 and S5 are repeated.

[0098] S7, the control mechanism controls the moving mechanism to drive the dilution container tray 700 to move one station, so that the dilution container is located below the detection mechanism 500. The control mechanism controls the lifting and driving component to drive the cleaning base 110 to descend until the electrode detection component of the detection mechanism 500 enters the dilution container. The electrode detection component places two parallel electrode plates in the solution to be tested in the dilution container, applies a certain potential, usually a sine wave voltage, to both ends of the electrode plates, and then measures the current flowing between the electrode plates. The conductivity is converted by Ohm's law, and the conductivity data is judged to quantitatively detect the cleanliness of the dilution container. The control mechanism controls the lifting and driving component to drive the cleaning base 110 to reset.

[0099] S8. Determine the conductivity.

[0100] When the conductivity is less than 1 μS / cm, it indicates that the cleanliness of the dilution container meets the requirements: the control mechanism controls the moving mechanism to drive the dilution container tray 700 to move one station, so that the dilution container is located below the drying mechanism 600; the control mechanism controls the lifting and lowering driving component to drive the cleaning base 110 to descend, so that the drying needle and the drying cleaning member of the drying mechanism 600 move into the dilution container to dry the dilution container.

[0101] When the conductivity is ≥1μS / cm, it indicates that the cleanliness of the dilution container does not meet the requirements: the control mechanism controls the alarm mechanism to give an alarm to remind the operator.

[0102] S9. When the cleanliness of the first dilution container meets the requirements, the second dilution container is cleaned. Specifically, the control mechanism controls the moving mechanism to drive the dilution container tray 700 to move so that the second dilution container is located below the first cleaning assembly 120, and steps S2 to S8 are repeated.

[0103] S10, when the cleanliness of the first dilution container does not meet the requirements, the control mechanism controls the moving mechanism to drive the dilution container tray 700 to move in the reverse direction, so that the first dilution container is relocated under the first second cleaning assembly 130, and steps S4 to S8 are repeated until the conductivity is less than 1 μS / cm. It should be noted that step S10 is an optional step.

[0104] In summary, the dilution container cleanliness quantitative determination device 10 can determine the cleanliness of the dilution container by reading the quantitative value in the dilution container, thereby facilitating the reuse of the dilution container and not affecting subsequent clinical test results.

[0105] In the above embodiments, the description of each embodiment has its own emphasis. For parts that are not described in detail in a certain embodiment, reference can be made to the relevant descriptions of other embodiments.

[0106] The technical features of the above-described embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above-described embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0107] The above-mentioned embodiments only express several implementation methods of the present invention, and the description thereof is relatively specific and detailed, but it cannot be understood as limiting the scope of the patent of the present invention. It should be pointed out that, for ordinary technicians in this field, several variations and improvements can be made without departing from the concept of the present invention, which all belong to the protection scope of the present invention. Therefore, the protection scope of the patent of the present invention shall be subject to the attached claims.

Claims

1. A device for quantitatively judging the cleanliness of a dilution container, characterized in that: The invention comprises a cleaning mechanism, a first liquid injection mechanism, a second liquid injection mechanism, a liquid suction mechanism, a detection mechanism, a drying mechanism and a moving mechanism, wherein the cleaning mechanism comprises a cleaning base and a first cleaning component and at least one second cleaning component movably connected to the cleaning base, wherein the first cleaning component comprises a first cleaning needle and a first waste liquid needle, and the second cleaning component comprises a second cleaning needle and a second waste liquid needle, wherein the first liquid injection mechanism can be communicated with the first cleaning needle to realize the separate injection of cleaning liquid into the first cleaning needle, and the second liquid injection mechanism can be communicated with each second cleaning needle to realize the separate injection of cleaning liquid into each second cleaning needle The first waste liquid needle and the second waste liquid needle are connected to the dilution container and the dilution container is provided with purified water, the liquid suction mechanism can be communicated with the first waste liquid needle and the second waste liquid needle separately to realize the suction of waste liquid through the first waste liquid needle or the second waste liquid needle, the detection mechanism is movably connected to the cleaning base to detect the conductivity of the liquid in the dilution container, the drying mechanism is movably connected to the cleaning base to dry the dilution container whose cleanliness meets the requirements, and the moving mechanism is connected to the cleaning base or the dilution container tray and drives it to move, so as to realize the dilution container to transfer position among the first cleaning component, the second cleaning component, the detection mechanism, and the drying mechanism.

2. The device for quantitatively judging the cleanliness of a dilution container according to claim 1, characterized in that: The cleaning base has a plurality of workstations sequentially and spaced apart in the same direction, the spacing between adjacent workstations is not less than the width of a dilution container, and the first cleaning component, the plurality of the second cleaning components, the detection mechanism, and the drying mechanism are sequentially arranged in different workstations.

3. The device for quantitatively judging the cleanliness of a dilution container according to claim 1, characterized in that: The first liquid injection mechanism includes a cleaning liquid storage tank, a first cleaning pipeline and a first diaphragm pump. The cleaning liquid storage tank is connected to the first cleaning needle through the first cleaning pipeline, and the first diaphragm pump is installed in the first cleaning pipeline.

4. The device for quantitatively judging the cleanliness of a dilution container according to claim 1, characterized in that: The second injection mechanism includes a purified water storage tank, a second cleaning pipeline, a second diaphragm pump and a control valve. The purified water storage tank is connected to the second cleaning needle through the second cleaning pipeline. The second diaphragm pump and the purified water storage tank are installed in the second cleaning pipeline.

5. The device for quantitatively judging the cleanliness of a dilution container according to claim 4, characterized in that: The second injection mechanism also includes a cleaning sub-pipeline, each of the second cleaning needles is connected in parallel to the second cleaning pipe through the cleaning sub-pipeline, each of the cleaning sub-pipeline is provided with the control valve, and the second diaphragm pump is installed in the second cleaning pipe.

6. The device for quantitatively judging the cleanliness of a dilution container according to any one of claims 1 to 5, characterized in that: The liquid aspiration mechanism includes a waste liquid storage box, a waste liquid pipeline and a waste liquid pump. The waste liquid storage box is connected to the first waste liquid needle and each of the second waste liquid needles through the waste liquid pipeline, and the waste liquid pump is arranged on the waste liquid pipeline.

7. The device for quantitatively judging the cleanliness of a dilution container according to any one of claims 1 to 5, characterized in that: The detection mechanism includes an electrode detection component, and the electrode detection component includes parallel electrode plates arranged in parallel. The parallel electrode plates can be loaded with a sinusoidal voltage to obtain the current between the parallel electrode plates, and the conductivity is converted through Ohm's law.

8. The device for quantitatively judging the cleanliness of a dilution container according to any one of claims 1 to 5, characterized in that: The drying mechanism comprises a drying needle and a drying cleaning piece. The drying needle is communicated with the liquid suction mechanism to realize adsorption and drying treatment of the dilution container. The drying cleaning piece is used for brushing and drying treatment of the dilution container.

9. The device for quantitatively judging the cleanliness of a dilution container according to any one of claims 1 to 5, characterized in that: The dilution container cleanliness quantitative judgment device further comprises a dilution container tray, on which a plurality of fixed grooves are arranged at intervals along the same direction, and the fixed grooves are used to accommodate the dilution containers to be cleaned, and the moving mechanism is connected to the dilution container tray and drives the dilution container tray to move, and the moving mechanism drives the dilution container tray to move each time by a distance equal to the width of one dilution container; And / or, the dilution container cleanliness quantitative determination device further comprises a lifting drive component, wherein the lifting drive component is connected to the cleaning base to drive the cleaning base to move upward and downward; And / or, the dilution container cleanliness quantitative determination device further comprises an alarm mechanism, which is electrically connected to the detection mechanism, and when the detection mechanism determines that the cleanliness of the dilution container does not meet the requirements according to the detection result, the alarm mechanism performs an alarm operation.

10. A method for quantitatively determining the cleanliness of a dilution container, characterized in that: The device for quantitatively judging the cleanliness degree of a dilution container according to any one of claims 1 to 9 comprises the following steps: Installing the dilution container to be cleaned on the dilution container tray so that the dilution container is located below the first cleaning component; Control the cleaning base to descend until the first waste liquid needle of the first cleaning assembly abuts against the bottom surface of the dilution container and absorbs the residual waste liquid in the dilution container; control the first liquid injection mechanism to inject cleaning liquid into the dilution container through the first cleaning needle; Control the moving mechanism to drive the dilution container tray to move one station, so that the dilution container is located below the Nth second cleaning component, N≥1, control the cleaning base to descend until the second waste liquid needle of the second cleaning component abuts against the bottom surface of the dilution container, control the liquid suction mechanism to suck the waste liquid in the dilution container through the second waste liquid needle, control the second liquid injection mechanism to inject purified water into the dilution container through the second cleaning needle, and repeat this step at least once; Control the moving mechanism to drive the dilution container tray to move one station so that the dilution container is located below the detection mechanism, control the cleaning base to descend until the detection mechanism enters the dilution container, and control the detection mechanism to detect the conductivity of the purified water in the dilution container; The conductivity is judged. When the conductivity is less than 1 μS / cm, it indicates that the cleanliness of the dilution container meets the requirements. The moving mechanism is controlled to drive the dilution container tray to move one station so that the dilution container is located below the drying mechanism. The drying mechanism is controlled to move into the dilution container to dry the dilution container. When the conductivity is greater than or equal to 1 μS / cm, it indicates that the cleanliness of the dilution container does not meet the requirements.

11. The method for quantitatively determining the cleanliness of a dilution container according to claim 10, characterized in that: The method for quantitatively determining the cleanliness level of the dilution container further comprises the following steps: When the cleanliness of the dilution container does not meet the requirements, the moving mechanism is controlled to drive the dilution container tray to move in reverse, so that the dilution container is located below the first second cleaning component, the cleaning base is controlled to descend until the second waste liquid needle of the second cleaning component abuts against the bottom surface of the dilution container, the liquid suction mechanism is controlled to suck the waste liquid in the dilution container through the second waste liquid needle, and the second liquid injection mechanism is controlled to inject purified water into the dilution container through the second cleaning needle, and this step is repeated at least once; The control detection mechanism performs the detection step again.

12. The method for quantitatively determining the cleanliness of a dilution container according to claim 10, characterized in that: The method for quantitatively determining the cleanliness level of the dilution container further comprises the following steps: When the cleanliness level of the dilution container does not meet the requirements, the control alarm mechanism will sound an alarm.

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