Traditional Chinese medicine plaster for treating rheumatic arthralgia

Abstract

The invention discloses a traditional Chinese medicine plaster for treating rheumatic arthralgia, which comprises the following components by weight: 10-15g of radix clematidis (raw), 10-16g of semen brassicae (raw), 10-18g of garden balsam stem (raw), 10-15g of asarum (raw), 15-25g of herba siegesbeckiae (raw) and 6-10g of calcined lygodium japonicum nidus (honeycomb fragments and lygodium japonicum are taken according to a ratio of 1: 1, put into a tank together, sealed with salt mud, calcined for storage, filtered and dried, and the plaster is used for treating rheumatic arthralgia. And screening out the lygodium japonicum to expose fire toxin). The Chinese herbal medicine formula is adopted, the medicine is specific, the power is high, the preparation method is simple, the prepared gel patch is pasted to the affected part, the treatment effect is good, the effects of dispelling cold and dredging collaterals, dispelling wind and eliminating dampness, relieving pain, resisting allergy (protecting skin application stimulation) and the like are achieved, and the gel patch is suitable for diseases caused by rheumatic arthralgia such as cervical spondylosis, rheumatic arthralgia, scapulohumeral periarthritis, lumbar disc herniation and traumatic injuries and has a wide application prospect. The medicine is good in curative effect, obvious in effect and easy to accept by patients.

Description

Technical Field

[0001] The invention belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine plaster for treating rheumatic arthritis. Background Art

[0002] Rheumatic arthralgia is caused by the combination of wind, cold and dampness. There are many clinical manifestations of rheumatic arthralgia, which can be divided into three types according to TCM syndrome differentiation: walking arthralgia, painful arthralgia and fixed arthralgia. The most severe wind is walking arthralgia, the most severe cold is painful arthralgia, and the most severe dampness is fixed arthralgia.

[0003] At present, the methods for treating rheumatic arthritis include fumigation, compress, acupoint injection therapy, acupuncture therapy and western medicine. Western medicine has obvious adverse reactions, and other methods have a long course of treatment and are not effective. With the high incidence of joint pain such as rheumatic arthritis, the endless medical and health care products on the market cannot meet people's needs, so more and more people are eager to get a simple, convenient, effective and inexpensive Chinese medicine external patch product. Summary of the invention

[0004] The purpose of the present invention is to overcome the deficiencies of the prior art and provide a Chinese medicine plaster for treating rheumatic arthritis to solve the above problems.

[0005] To achieve the above object, the present invention adopts the following technical solutions:

[0006] A Chinese medicine plaster for treating rheumatic arthritis, characterized in that the components are as follows by weight: 10-15 grams of clematis (raw), 10-16 grams of white mustard seeds (raw), 10-18 grams of radix scutellariae (raw), 10-15 grams of asarum (raw), 15-25 grams of sisseed (raw), 6-10 grams of calcined honeycomb (honeycomb fragments and lycopodii are taken in a 1:1 ratio, put into a jar together, sealed with salt mud, calcined to preserve, sieve out the lycopodii, and remove the fire poison with the dew), 0.2-2 grams of a surfactant, 0.05-1 grams of a cross-linking agent, 1.5-2 grams of a thickener, and 0.1-2 grams of a regulator.

[0007] Preferably, the weight ratio of each component is: 10-15 grams of Clematis (raw), 10-16 grams of white mustard (raw), 10-18 grams of Radix Polygoni Multiflori (raw), 10-15 grams of Asarum (raw), 15-25 grams of Siegesbeckia (raw), 6-10 grams of Lycopodiella cava calcined honeycomb (take honeycomb fragments and Lycopodiella cava in a 1:1 ratio, put them together in a jar, seal with salt mud, calcine for storage, sieve out the Lycopodiella cava, and use the dew to remove fire poison), 1 gram of surfactant, 0.5 grams of cross-linking agent, 1.5 grams of thickener, and 1 gram of regulator.

[0008] Preferably, the cross-linking agent includes one or a combination of two of aluminum hydroxide, aluminum chloride, aluminum nitrate, aluminum carbonate, and potassium aluminum sulfate.

[0009] Preferably, the thickener includes one or more combinations of methyl cellulose, carboxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl methyl cellulose, xanthan gum, and sodium carboxymethyl cellulose.

[0010] Preferably, the regulator includes one or more combinations of lactic acid, citric acid and malic acid.

[0011] A Chinese medicine plaster for treating rheumatic arthritis is prepared according to the following steps:

[0012] (1) Weigh the above raw materials according to weight ratio, add 1 kg of water, stir at room temperature, swell, mix evenly, and set aside;

[0013] (2) adding a surfactant in step (1) and mixing uniformly to obtain an alcohol phase material;

[0014] (3) Mix the thickener and the regulator evenly, and dissolve them in purified water to obtain an aqueous phase material;

[0015] (4) the material of step (2) and the material of step (3) are mixed uniformly;

[0016] (5) taking the cross-linking agent and the material of step (4) and mixing them evenly, starting the gel cross-linking, stirring at a frequency of 15 / 40 Hz, a stirring temperature of ≤38° C., and a stirring time of 10-15 min to obtain a gel paste;

[0017] (6) The gel paste is coated on a non-woven fabric through a coating and cutting machine to obtain a semi-finished product. The semi-finished product is left to stand for 24 hours at a temperature of 25-30° C. and a relative humidity of 60%-75% to obtain the desired gel patch. The patch is cut into patches with a diameter of 10 cm and then packaged and sealed.

[0018] The medicinal functions of each component of the patented medicine of the present invention are:

[0019] The main effects of raw Clematis are dispelling wind and dampness, unblocking meridians and relieving pain, and it is mainly used to treat rheumatic arthralgia; the main effects of raw Glechoma longituba are dispelling wind and dampness, relaxing muscles and activating blood circulation, dispersing blood stasis and reducing swelling, detoxifying and relieving pain, and it is mainly used to treat rheumatic arthralgia, lumbar sprain, and tightening contracture; the main effects of raw Siegesbeckia sibiricum are dispelling wind and dampness and benefiting joints, and it is mainly used to treat rheumatic arthralgia, weakness of muscles and bones, soreness of waist and knees, and paralysis of limbs; the main effects of raw white mustard seeds are warming the lungs and resolving phlegm, benefiting qi and dispersing nodules, unblocking meridians and relieving pain, and it is mainly used to treat cold phlegm cough, phlegm stagnation in meridians, and numbness and pain in joints; the main effects of raw Asarum are relieving exterior symptoms and dispersing cold, dispelling wind and relieving pain, and unblocking the orifices, and it is mainly used to treat wind-cold colds, headaches, toothaches, nasal congestion and sinewy sinusitis, and rheumatic arthralgia; the effect of dew beehive (calcined together with sea sand) is to attack toxins and kill insects, dispel wind and relieve pain, and it is used for rheumatic arthralgia, toothache, sores, swelling and poison, and stubborn ringworm and itching.

[0020] The patent of this invention focuses on using the dried mature spores of Lygodium japonicum, which has the characteristics of sweet, salty and cold, and calcining them together with the raw honeycomb, thereby eliminating the tendency of the honeycomb to float and reducing the toxicity of the raw honeycomb, making the effects of the honeycomb in dispelling wind and relieving pain, and resisting allergies (protecting skin from irritation) particularly obvious. In addition, the main medicine is composed of raw Clematis chinensis, raw Radix Penicilliae, and raw Herba Siegesbeckiae, which are the main medicines for treating rheumatic arthralgia, and can be called the nemesis of rheumatic arthralgia.

[0021] Raw Clematis: pungent, salty and warm in nature, it belongs to the bladder meridian. Its main effects are: dispelling wind and dampness, dredge meridians and relieve pain, and eliminate bone stagnation. It is used for rheumatic arthralgia.

[0022] Raw radix thunbergii: pungent and warm in nature, it enters the liver and kidney meridians. Its main effects are: dispelling wind and dampness, relaxing muscles and activating blood circulation, dispersing blood stasis and reducing swelling, detoxifying and relieving pain. It is used for rheumatic arthralgia, lumbar sprain, and tightening contracture.

[0023] Raw Siegesbeckia: It has bitter and cold properties and enters the liver and kidney meridians. Its main effects are: removing rheumatism, benefiting joints, and detoxifying. It is used for rheumatic pain, weakness of tendons and bones, soreness of waist and knees, and paralysis of limbs.

[0024] Raw white mustard seeds: pungent and warm in nature, enters the lung and stomach meridians. The main effects are: warming the lungs and resolving phlegm, promoting qi and dispersing stagnation, unblocking meridians and relieving pain. Used for cough caused by cold phlegm, phlegm stagnation in the meridians, numbness and pain in the joints, and swelling and poison in the genitals.

[0025] Raw Asarum: pungent and warm in nature, slightly toxic, tends to rise and float, and enters the heart, lung, and kidney meridians. The main effects are: dispelling cold, dispelling wind and relieving pain, opening the orifices, warming the lungs and transforming fluid. It is used for colds, headaches, toothaches, nasal congestion and sinusitis, and rheumatic pain.

[0026] Beehive (calcined with sea sand): The drug is sweet and mild, slightly toxic, tends to rise and floats, and enters the stomach meridian. The effects are: attacking poison and killing insects, dispelling wind and relieving pain. It is used for rheumatic arthralgia, toothache, sores, swelling and poison, stubborn ringworm and itching.

[0027] After years of clinical use, it has been proven that the honeycombs of the present invention must be calcined together with Lygodium japonicum, because the dried mature spores of Lygodium japonicum have the characteristics of sweet, salty and cold, which can eliminate the tendency of honeycombs to float and reduce the toxicity of raw honeycombs, making the effects of honeycombs in dispelling wind, relieving pain and resisting allergies (protecting skin from irritation) more obvious. This is the special feature of the present invention's use of Lygodium japonicum to calcine raw honeycombs.

[0028] The invention has the beneficial effects as follows: in the Chinese herbal medicine formula of the invention, three medicines, such as raw clematis root, raw radix polygoni lobatae, and raw schizonepeta, which are mainly used to treat rheumatic arthralgia, are used together to dispel wind and dampness, dredge the meridians and relieve pain as the main medicine; raw white mustard seeds are suitable for external application, and their effects of dispelling wind and cold, reducing swelling and relieving pain are particularly obvious, and there is no lack of single use in folk prescriptions, so it is not too much to be a ministerial medicine; raw asarum has the merits of dispelling cold, dispelling wind and relieving pain, so it is an adjuvant; sea gold sand calcined raw honeycomb has the special effect of anti-allergy and better protects the skin at the application site, and is used together with other medicines as a guiding medicine. The six-flavor Chinese medicine of the plaster of the invention has a simple plaster preparation method, and the obtained gel patch is attached to the affected part, has good therapeutic effect, has the effects of dispelling cold and dredge the meridians, dispelling wind and dampness, relieving pain, and anti-allergy, and the medicine is special and powerful, and can treat the stubborn disease of rheumatic arthralgia. It is suitable for diseases caused by rheumatic diseases such as cervical spondylosis, rheumatic joint pain, frozen shoulder, lumbar disc herniation, and traumatic injuries, with good efficacy and obvious results. DETAILED DESCRIPTION

[0029] In order to better understand the present invention, the technical solution of the present invention is described in detail with specific examples below.

[0030] A Chinese medicine plaster for treating rheumatic arthritis, comprising the following components by weight: 10-15 grams of clematis (raw), 10-16 grams of white mustard seeds (raw), 10-18 grams of radix scutellariae (raw), 10-15 grams of asarum (raw), 15-25 grams of sisseed (raw), 6-10 grams of calcined honeycomb with sea sand (honeycomb fragments and sea sand are taken in a ratio of 1:1, put into a jar together, sealed with salt mud, calcined to preserve the properties, the sea sand is sieved out, and the dew is used to remove fire poison), 1 gram of a surfactant, 0.5 gram of a cross-linking agent, 1.5 grams of a thickener, and 1 gram of a regulator.

[0031] A Chinese medicine plaster for treating rheumatic arthritis is prepared according to the following steps:

[0032] (1) Weigh the above raw materials according to weight ratio, add 1 kg of water, stir at room temperature, swell, mix evenly, and set aside;

[0033] (2) adding a surfactant in step (1) and mixing uniformly to obtain an alcohol phase material;

[0034] (3) Mix the thickener and the regulator evenly, and dissolve them in purified water to obtain an aqueous phase material;

[0035] (4) the material of step (2) and the material of step (3) are mixed uniformly;

[0036] (5) taking the cross-linking agent and the material of step (4) and mixing them evenly, starting the gel cross-linking, stirring at a frequency of 15 / 40 Hz, a stirring temperature of ≤38° C., and a stirring time of 10-15 min to obtain a gel paste;

[0037] (6) The gel paste is coated on a non-woven fabric through a coating and cutting machine to obtain a semi-finished product. The semi-finished product is left to stand for 24 hours at a temperature of 25-30° C. and a relative humidity of 60%-75% to obtain the desired gel patch. The patch is cut into patches with a diameter of 10 cm and then packaged and sealed.

[0038] The therapeutic effect of the present invention is illustrated by the following clinical cases.

[0039] Actual case 1

[0040] Mr. Li, male, 57 years old, has been working away from home in recent years. Due to the limited warm and dry living environment and simple housing, he developed a disease in his knee joints. Whenever the weather is cloudy or the temperature drops, his knees hurt severely, which was relieved by hot compress. He was diagnosed with "rheumatic knee arthritis" by the local hospital. The pain was unbearable when he walked, and he rested at home for several days, but there was no obvious improvement. He was given a gel ointment for external application, and the pain improved after two doses and he was cured after one course of treatment. He had no discomfort during the three-year follow-up.

[0041] Actual case 2

[0042] Zhao, male, 43 years old, was busy with work, facing the computer all day, with his back against the air conditioner blowing directly at him, which caused him to be afraid to raise his right shoulder and upper limb, making it difficult for him to wash his face and get dressed. The pain was worse at night. After oral Western medicine and applying moisturizing plasters, there was no effect, so he came to the hospital for "shoulder periarthritis" and was given a gel ointment for external application. The symptoms improved after one dose and he was cured after half a course of treatment. There was no recurrence during the two-year follow-up.

[0043] Actual case 3

[0044] Cui, male, 56 years old, has had rheumatic joint pain for several years. According to him, all kinds of plasters he used were ineffective, and acupuncture, electrotherapy, injections and medications did not cure his disease. He said that he could not stay in the air-conditioned room for a minute even in the hot summer, and the cold wind pierced his bones. It has been worse for more than half a month, so he came to the clinic and was given a gel ointment for external application. After five doses, he got better, and after two courses of treatment, he was cured. He has not had pain for two years of follow-up.

[0045] The invention adopts a Chinese herbal medicine formula, has a simple preparation method, and the prepared gel patch is attached to the affected part, has good therapeutic effect, has the effects of dispelling cold and dredge meridians, dispelling wind and dampness, relieving pain, and resisting allergy, and is suitable for treating stubborn diseases of rheumatism and arthralgia. It is suitable for cervical spondylosis, rheumatic joint pain, scapulohumeral periarthritis, lumbar disc herniation, traumatic injury and other diseases caused by rheumatism and arthralgia, and has good therapeutic effect and obvious effect.

[0046] The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention. It should be understood by those skilled in the art that the present invention is not limited to the above embodiments. The above embodiments and descriptions are only for explaining the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which fall within the scope of the present invention to be protected. The scope of protection of the present invention is defined by the attached claims and their equivalents.

Claims

1. A Chinese medicine plaster for treating rheumatic arthritis, characterized in that: The weight ratio of each ingredient is as follows: 10-15 grams of Clematis (raw), 10-16 grams of white mustard seeds (raw), 10-18 grams of Radix Polygoni Multiflori (raw), 10-15 grams of Asarum (raw), 15-25 grams of Siegesbeckia (raw), 6-10 grams of calcined honeycomb (take honeycomb fragments and sea sand in a 1:1 ratio, put them together in a jar, seal with salt mud, calcine to preserve, sieve out the sea sand, and use the dew to remove fire toxins), 0.2-2 grams of surfactant, 0.05-1 grams of cross-linking agent, 1.5-2 grams of thickener, and 0.1-2 grams of regulator.

2. A Chinese medicine plaster for treating rheumatic arthritis according to claim 1, characterized in that: The weight ratio of each ingredient is as follows: 10-15 grams of Clematis (raw), 10-16 grams of white mustard seeds (raw), 10-18 grams of Radix Polygoni Multiflori (raw), 10-15 grams of Asarum (raw), 15-25 grams of Siegesbeckia (raw), 6-10 grams of calcined honeycomb (take honeycomb fragments and calcined honeycomb in a 1:1 ratio, put them together in a jar, seal with salt mud, calcine them, sieve out the calcined honeycomb, and use the dew to remove fire toxins), 1 gram of surfactant, 0.5 grams of cross-linking agent, 1.5 grams of thickener, and 1 gram of regulator.

3. A Chinese medicine plaster for treating rheumatic arthritis according to claim 1, characterized in that: The cross-linking agent includes one or a combination of two of aluminum hydroxide, aluminum chloride, aluminum nitrate, aluminum carbonate, and potassium aluminum sulfate.

4. A Chinese medicine plaster for treating rheumatic arthritis according to claim 1, characterized in that: The thickener includes one or more combinations of methyl cellulose, carboxymethyl cellulose, hydroxyethyl cellulose, hydroxypropyl methyl cellulose, xanthan gum, and sodium carboxymethyl cellulose.

5. A Chinese medicine plaster for treating rheumatic arthritis according to claim 1, characterized in that: The regulator includes one or more combinations of lactic acid, citric acid and malic acid.

6. A Chinese medicine plaster for treating rheumatic arthritis according to claim 1, characterized in that: Follow these steps to make it: (1) Weigh the above raw materials according to weight ratio, add 1 kg of water, stir at room temperature, swell, mix evenly, and set aside; (2) adding a surfactant in step (1) and mixing uniformly to obtain an alcohol phase material; (3) Mix the thickener and the regulator evenly, and dissolve them in purified water to obtain an aqueous phase material; (4) the material of step (2) and the material of step (3) are mixed uniformly; (5) taking the cross-linking agent and the material of step (4) and mixing them evenly, starting the gel cross-linking, stirring at a frequency of 15 / 40 Hz, a stirring temperature of ≤38° C., and a stirring time of 10-15 min to obtain a gel paste; (6) The gel paste is coated on a non-woven fabric through a coating and cutting machine to obtain a semi-finished product. The semi-finished product is left to stand for 24 hours at a temperature of 25-30° C. and a relative humidity of 60%-75% to obtain the desired gel patch. The patch is cut into patches with a diameter of 10 cm and then packaged and sealed.