Magnetic type embolism protection device and embolism system

Abstract

The invention discloses a magnetic type embolism protection device and an embolism protection system, and belongs to the technical field of medical instruments, the magnetic type embolism protection device comprises a catheter and an umbrella-shaped filter screen assembly arranged on the outer side wall of the far end of the catheter, and a permanent magnet is arranged in the catheter to be matched to open and contract an umbrella of the filter screen assembly; a first cavity, a second cavity and a guide wire cavity are formed in the catheter in the length direction of the catheter, the first cavity is formed in the position close to the inner wall of the catheter, the second cavity and the guide wire cavity are formed in the catheter side by side, and the far end of the first cavity and the far end of the second cavity communicate with each other through a communicating hole. The first hole is communicated with the first cavity. The first cavity is pressurized to enable the permanent magnet to generate displacement so as to further enable the unfolding rod and the distraction rod to be unfolded and contracted through magnetic pushing, the unfolding size of the umbrella stand is controlled to adapt to blood vessels with different inner diameters, adaptability is high, the structure is stable, control is convenient, free thrombus can be effectively intercepted, the probability of thromboembolism is reduced, and the success rate of an operation is increased.

Description

Technical Field

[0001] The present invention belongs to the field of medical devices, and in particular relates to a magnetic embolism protection device and an embolism system. Background Art

[0002] The phenomenon of abnormal substances insoluble in blood appearing in the circulating blood and flowing with the blood to a distant place to block the blood vessel cavity is called embolism. Thrombosis is caused by the presence of certain predisposing factors, which in turn activate the endogenous or exogenous coagulation system. Platelets and other formed elements in the blood abnormally aggregate in the circulating blood to form blood clots. Blood clots may occur on the inner wall of the heart or the wall of blood vessels, causing blood vessel obstruction or embolism, and subsequent serious physical damage. Thrombosis spreads throughout the cardiovascular system and affects tissues and organs throughout the body. After thrombosis, blood vessel occlusion and blood flow obstruction cause ischemia, hypoxia, and even necrosis of the related vascular innervated tissues, resulting in symptoms of corresponding tissue and organ dysfunction.

[0003] In clinical practice, anticoagulants and thrombolytic drugs are used for treatment, but the treatment effect is extremely insignificant. The larger the diameter of the blood vessel blocked by the thrombus, the worse the treatment effect, the lower the recanalization rate of the blood vessel, the longer the time required for recanalization, and some patients are not suitable for thrombolytic therapy. When using interventional means to treat vascular embolism, the narrowed area of ​​the blood vessel is often blocked by thrombus or tissue shedding, causing vascular necrosis, which increases the risk of surgery. In response to this problem, an embolic protection device is proposed. The protection device intercepts thrombus or tissue at the distal end with a net without affecting the normal flow of blood, and takes it out of the body to ensure the normal operation and improve the success rate of the operation. However, the existing embolic protection devices mostly use the movement of the catheter to provide the opening and closing of the net structure, and the mesh structure is mostly composed of memory alloy filaments. The movement of the catheter drives the opening of the net structure, which requires high welding technology, and requires multi-layer casing, which is complex in structure. The structure composed of memory alloy filaments is easily deformed by blood flow.

[0004] Patents for some embolic protection devices are disclosed in the prior art, among which the invention patent with the announcement number CN113425374A discloses a disposable embolic protection umbrella, including a transport guidewire, a filter mesh bag and a transport and recovery sheath, the transport guidewire includes a distal guidewire and a proximal guidewire... The transport and recovery sheath includes a transport sheath and a recovery sheath, the transport sheath is used to store the transport guidewire and the filter mesh bag, the transport sheath and the recovery sheath are connected by a connecting assembly; the side wall of the transport sheath is also provided with a first opening groove for the transport guidewire and the filter mesh bag to pass through. Although the problem that the transport structure of the embolic protection umbrella is relatively hard and the overall flexibility is insufficient has been solved, there are still problems that the grid structure has high requirements for welding technology and high production difficulty, and the structure of the filamentary wire is easily affected by blood flow and deformed, affecting the effect.

[0005] In view of this, the inventor conducted in-depth research on this demand, which resulted in this case. Summary of the invention

[0006] In order to overcome the problems in the prior art that the grid structure has high requirements for welding technology and is difficult to produce, and the structure of the filamentary wire is easily deformed by the blood flow and affects the effect, the present invention provides a magnetic embolic protection device and embolic system.

[0007] A first aspect of the present invention provides a magnetic embolic protection device, comprising a catheter and an umbrella-shaped filter assembly arranged on the outer side wall of the distal end of the catheter, wherein a permanent magnet is arranged in the catheter to cooperate in expanding and contracting the filter assembly; the catheter is provided with a first cavity, a second cavity and a guide wire cavity along its length direction, the first cavity is opened near the inner wall of the catheter, the second cavity and the guide wire cavity are opened side by side in the catheter, the distal ends of the first cavity and the second cavity are connected to each other by opening a connecting hole, the permanent magnet is placed in the middle of the first cavity, the proximal end of the catheter is provided with a first hole, and the first hole is connected to the first cavity.

[0008] A permanent magnet is arranged inside the catheter to cooperate with an umbrella-shaped filter assembly connected to the outside of the catheter. The permanent magnet is displaced by filling the first cavity with pressure, and the filter assembly is further expanded and contracted by magnetic force. The size of the umbrella frame opening is controlled to adapt to blood vessels with different inner diameters, making it highly adaptable. The embolic protection device has a stable structure and is easy to control. It can effectively intercept free thrombi, reduce the chance of thromboembolism, and improve the success rate of surgery. A three-lumen tube combined with a permanent magnet can complete the expansion and contraction of the device, reducing the difficulty of the manufacturing process of the entire device. A rod structure is used to reduce the deformation of the umbrella frame affected by blood flow and improve stability.

[0009] Furthermore, the filter assembly includes an umbrella frame, a fixed ring and a movable ring, the fixed ring is fixedly connected to the conduit, and the fixed ring is fixedly connected to the far end of the umbrella frame, the movable ring is slidably sleeved on the outer wall of the conduit, and the movable ring is fixedly connected to the proximal end of the umbrella frame, and the movable ring and the permanent magnet open and close the umbrella frame through magnetic force.

[0010] Through the above technical solution, the connection between the fixed ring and the movable ring and the umbrella frame enables the filter assembly to be coaxially arranged with the catheter, so that the umbrella frame has good wall adhesion around the catheter, and can prevent thrombus from escaping from the gap between the embolic protection device and the blood vessel wall in multiple directions, resulting in a better capture effect.

[0011] Furthermore, the umbrella stand includes a plurality of unfolding rods and a plurality of spreading rods, one end of each of the unfolding rods is rotatably connected to the fixed ring via a first connecting ring, and the unfolding rods are equidistantly arranged on the fixed ring, one end of each of the spreading rods is rotatably connected to the movable sleeve ring via a second connecting ring, and the spreading rods are equidistantly arranged on the movable sleeve ring, and the other end of the spreading rod is rotatably connected to the middle part of the unfolding rod via a limiting shaft.

[0012] Through the above technical solution, an expansion rod and a spreading rod are arranged to be connected with the fixed ring and the movable ring, and the expansion rod and the spreading rod provide the filter assembly with higher rigidity, so that the filter assembly can better capture the thrombus in the blood vessel during use.

[0013] Furthermore, a first connecting hole is provided at the free end of the expansion rod, a connecting groove is provided in the middle of the expansion rod, the connecting groove matches the expansion rod, second connecting holes are provided on both sides of the connecting groove, and the first connecting hole and the second connecting hole match the limiting shaft.

[0014] Through the above technical solution, a connecting groove is opened in the middle of the expansion rod, which ensures the rotational connection between the expansion rod and the expansion rod. At the same time, the movable ring transfers the force to the expansion rod through the expansion rod when subjected to magnetic force, so that the expansion rod can complete the expansion and contraction actions.

[0015] Furthermore, a compression mesh surface is provided on the outer side surface of the expansion rod facing away from the movable sleeve, the compression mesh surface is fixedly connected to the expansion rod, and a plurality of leakage holes are opened on the compression mesh surface between the expansion rods.

[0016] Through the above technical solution, a compression mesh is provided on the outside of the deployment rod, which can prevent the thrombus from escaping in the gap between the deployment rod and the expansion rod during use, and the capture effect is better. At the same time, by opening leakage holes on the compression mesh, it is avoided that the blood circulation is blocked during the thrombus removal process and the operation is affected.

[0017] Furthermore, a plurality of drug outlet holes are provided on two side surfaces of the expansion rod adjacent to the compression mesh surface, drugs for thrombolysis are arranged in the drug outlet holes, and a water-based coating is provided at the openings of the drug outlet holes.

[0018] Through the above technical solution, drug outlet holes that can be filled with thrombolytic drugs are arranged on both sides of the expansion rod that are perpendicular to the compression mesh surface. The thrombus contained in the compression mesh surface is dissolved by the released thrombolytic drugs. Since the compression mesh surface is arranged on the outside of the expansion rod when entering the blood vessel, the drug can be prevented from being released prematurely, and the drug can be released again at a specific position to increase the benefit rate, thereby leading out the thrombus and unblocking the blood.

[0019] Furthermore, medicine storage spaces are provided inside the two ends of the deployment rod away from the connection groove, and the medicine outlet hole is communicated with the medicine storage space.

[0020] Through the above technical solution, drug storage spaces are opened on both sides of the deployment rod and the connecting groove at a certain distance and are connected to the drug outlet hole. The setting of the drug storage space ensures that there is enough space in the device to place the thrombolytic agent, avoiding the situation where the aqueous film dissolves and the agent is released prematurely, resulting in insufficient filled drug affecting the thrombolytic effect.

[0021] Furthermore, the permanent magnet is loosely matched with the inner wall of the catheter, and the length of the permanent magnet is greater than the inner diameter of the catheter.

[0022] Furthermore, the proximal end and the distal end of the permanent magnet are respectively connected to a first traction wire and a second traction wire, the proximal end of the first traction wire extends out of the first hole along the first cavity, and the proximal end of the second traction wire extends out of the second cavity along the second cavity.

[0023] Through the above technical solution, the length of the permanent magnet is set to be larger than the inner diameter of the catheter, which can ensure that the permanent magnet moves back and forth in the first cavity and also ensure that the moving ring has a suitable thrust or pull.

[0024] A second aspect of the present invention provides a magnetic embolic system, comprising the embolic protection device as described above and a delivery catheter, wherein the delivery catheter can receive the embolic protection device therein and deliver the embolic protection device.

[0025] Compared with the prior art, the technical solution of the present invention has the following beneficial effects:

[0026] (1) A permanent magnet is arranged inside the catheter to cooperate with an umbrella frame connected to the outside of the catheter. The permanent magnet is displaced by filling the first cavity with pressure, and the deployment rod and the opening rod are further pushed to expand by magnetic force. The opening size of the umbrella frame is controlled to adapt to blood vessels with different inner diameters, making it highly adaptable. The embolic protection device has a stable structure and is easy to control. It can effectively intercept free thrombi, reduce the probability of thromboembolism, and improve the success rate of surgery. A three-lumen tube combined with a permanent magnet can complete the opening and contraction of the device, reducing the difficulty of the manufacturing process of the entire device. The rod structure is used to reduce the deformation of the umbrella frame due to blood flow, thereby improving stability.

[0027] (2) By setting a compression mesh surface outside the deployment rod, the thrombus is prevented from escaping in the gap between the deployment rod and the expansion rod during use, and the capture effect is better. At the same time, by setting leakage holes on the compression mesh surface, the blood circulation is blocked during the thrombus removal process, which causes tissue ischemia and damage, thereby improving the safety of the operation.

[0028] (3) A drug outlet hole is provided on the expansion rod and a drug storage space for placing a thrombolytic agent is opened therein, and the drug outlet hole is sealed with a water-soluble film. After the expansion rod is expanded, the film dissolves the thrombolytic agent and is integrated into the blood during the blood flow, thereby performing thrombolysis treatment on the captured thrombus, clearing the thrombus in the blood vessel more completely, and also shortening the cleaning time. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required for use in the embodiments will be briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present invention and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without paying creative work.

[0030] Figure 1 It is a structural schematic diagram of a magnetic embolic protection device of the present invention;

[0031] Figure 2 It is a structural schematic diagram of a magnetic embolic protection device of the present invention from another angle;

[0032] Figure 3 It is a schematic cross-sectional view of a catheter at a communication hole in a magnetic embolic protection device of the present invention;

[0033] Figure 4 It is a schematic diagram of an umbrella stand in a magnetic embolic protection device of the present invention;

[0034] Figure 5 It is a schematic diagram of a deployment rod in a magnetic embolic protection device of the present invention;

[0035] Figure 6 It is a schematic cross-sectional view of an expansion rod in a magnetic embolic protection device of the present invention;

[0036] Figure 7 It is a schematic diagram of a filter assembly in a magnetic embolic protection device of the present invention;

[0037] Figure 8 It is a schematic diagram of the charging direction of a magnetic embolic protection device of the present invention;

[0038] Fig. 9 It is a schematic diagram of a first traction wire and a second traction wire connected to a permanent magnet in a magnetic embolic protection device according to another embodiment of the present invention;

[0039] In the figure, 1. catheter; 2. filter assembly; 3. permanent magnet; 4. first cavity; 5. second cavity; 6. guide wire cavity; 7. connecting hole; 8. first hole; 9. umbrella frame; 10. fixed ring; 11. movable sleeve; 12. unfolding rod; 13. opening rod; 14. second connecting ring; 15. limiting shaft; 16. connecting groove; 17. second connecting hole; 18. compression mesh surface; 19. leakage hole; 20. medicine outlet hole; 21. medicine storage space; 22. first traction wire; 23. second traction wire. DETAILED DESCRIPTION

[0040] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Therefore, the following detailed description of the embodiments of the present invention provided in the drawings is not intended to limit the scope of the claimed invention, but merely represents the selected embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0041] This embodiment adopts a method of arranging a permanent magnet inside the catheter to cooperate with an umbrella frame connected to the outside of the catheter, and by pressurizing the first cavity to displace the permanent magnet, the deployment rod and the opening rod are further pushed by magnetic force to expand and contract, and the size of the umbrella frame is controlled to adapt to blood vessels with different inner diameters, making it highly adaptable. The embolic protection device has a stable structure and is easy to control, which can effectively intercept free thrombi, reduce the probability of thromboembolism, and improve the success rate of surgery. The specific implementation is as follows:

[0042] like Figure 1-9 As shown, a magnetic embolic protection device comprises a catheter 1 and an umbrella-shaped filter assembly 2 arranged on the outer side wall of the distal end of the catheter 1, wherein a permanent magnet 3 is arranged in the catheter 1 to cooperate with the umbrella-shaped filter assembly 2 to expand and contract; the catheter 1 is provided with a first cavity 4, a second cavity 5 and a guide wire cavity 6 along its length direction, the first cavity 4 is opened near the inner wall of the catheter 1, the second cavity 5 and the guide wire cavity 6 are opened side by side on the side where the inner wall of the catheter 1 and the first cavity 4 are spaced apart by a larger distance, the distal ends of the first cavity 4 and the second cavity 51 are connected to each other by opening a connecting hole 7, the permanent magnet 3 is placed in the middle of the first cavity 4, the proximal end of the catheter 1 is provided with a first hole 8, and the first hole 8 is connected to the first cavity 4.

[0043] A permanent magnet 3 is arranged inside the catheter 1 to cooperate with an umbrella-shaped filter assembly 2 connected to the outside of the catheter 1. The permanent magnet 3 is displaced by pressurizing the first cavity 4, and the filter assembly 2 is further expanded by magnetic force. At the same time, a connecting hole 7 connected to the second cavity 5 is opened at the far end of the first cavity 4 to complete the pressure relief and shrink the filter assembly 2. The size of the opening of the umbrella frame 9 is controlled to adapt to blood vessels with different inner diameters, making it highly adaptable. In addition, the embolic protection device has a stable structure and is easy to control, and can effectively intercept free thrombi. In addition, the connecting hole 7 is arranged to discharge the pressure that enters the first cavity 4 through the first hole 8, ensuring that the expansion rod 13 is expanded outward to a certain angle and the expansion rod 13 can be closed inward by pressure relief.

[0044] Here, the pressure charging method can be to use a pressure pump to connect the proximal end of the first chamber 4, input gas into the first chamber 4, push the permanent magnet 3 to move to the distal end, and after reaching the preset position, close the proximal end of the second chamber 5, maintain the pressure, and keep the umbrella stable. The pressure relief method can be to open the proximal end of the second chamber 5 to the atmosphere, suck the gas in the first chamber 4, push the permanent magnet 3 to move to the proximal end, and deflate the umbrella.

[0045] As a preferred embodiment, the filter assembly 2 includes an umbrella frame 9, a fixed ring 10 and a movable ring 11. The fixed ring 10 is fixedly connected to the catheter 1, and the fixed ring 10 is fixedly connected to the far end of the umbrella frame 9. The movable ring 11 is slidably mounted on the outer wall of the catheter 1, and the movable ring 11 is fixedly connected to the proximal end of the umbrella frame 9. The movable ring 11 and the permanent magnet 3 open and close the umbrella frame 9 through the magnetic force.

[0046] Here, the connection between the fixed ring 10 and the movable sleeve ring 11 and the umbrella frame 9 enables the filter assembly 2 to be coaxially arranged with the catheter 1, so that the umbrella frame 9 has good wall adhesion in the circumferential direction, and can prevent thrombus from escaping from the gap between the embolic protection device and the blood vessel wall in multiple directions, and the capture effect is better.

[0047] As a preferred embodiment, the umbrella frame 9 includes a plurality of unfolding rods 12 and a plurality of spreading rods 13, one end of each of the unfolding rods 12 is rotatably connected to the fixed ring 10 via a first connecting ring, and the unfolding rods 12 are equidistantly arranged on the fixed ring 10, one end of each of the spreading rods 13 is rotatably connected to the movable sleeve 11 via a second connecting ring 14, and the spreading rods 13 are equidistantly arranged on the movable sleeve 11, and the other end of the spreading rod 13 is rotatably connected to the middle part of the unfolding rod 12 via a limiting shaft 15.

[0048] Here, an expansion rod 12 and a spreading rod 13 are provided to be connected with the fixed ring 10 and the movable sleeve ring 11, and the expansion rod 12 and the spreading rod 13 provide the filter assembly 2 with higher rigidity, so that the filter assembly 2 can better capture the thrombus in the blood vessel during use.

[0049] As a preferred embodiment, a first connecting hole is opened at the free end of the expansion rod 13, a connecting groove 16 is opened in the middle of the expansion rod 12, the connecting groove 16 matches the expansion rod 13, and second connecting holes 17 are opened on both sides of the connecting groove 16, and the first connecting hole and the second connecting hole 17 match the limiting shaft 15.

[0050] Here, a connecting groove 16 is opened in the middle of the expansion rod 12, which ensures the rotational connection between the expansion rod 13 and the expansion rod 12, and also enables the movable ring 11 to transfer the force to the expansion rod 12 through the expansion rod 13 when subjected to magnetic force, so that the expansion rod 12 can complete the expansion and contraction actions.

[0051] Here, in order to ensure that the moving collar 11 can be pulled by magnetic force, the moving collar 11 is made of ferromagnetic material, which is easily magnetized and exhibits magnetism. Therefore, under the action of the permanent magnet 3, the moving collar 11 will be obviously attracted.

[0052] The material of the movable ring 11 is a substance containing at least one element of iron, cobalt and nickel. Preferably, the movable ring 11 is made of one of neodymium iron boron magnets, aluminum nickel cobalt magnets, samarium cobalt magnets and ferrite magnets.

[0053] As a preferred embodiment, a compression mesh 18 is provided on the outer side of the deployment rod 12 facing away from the movable ring 11 , and the compression mesh 18 is fixedly connected to the deployment rod 12 . A plurality of leakage holes 19 are provided on the compression mesh 18 between the deployment rods 12 .

[0054] Here, a compression mesh 18 is provided outside the deployment rod 12, which can prevent the thrombus from escaping in the gap between the deployment rod 12 and the expansion rod 13 during use, thereby achieving a better capture effect. At the same time, leakage holes 19 are provided on the compression mesh 18 to avoid blocking blood circulation during thrombus removal, thereby causing tissue ischemia and damage, thereby improving surgical safety.

[0055] As a preferred embodiment, a plurality of drug outlet holes 20 are provided on the two side surfaces of the expansion rod 12 adjacent to the compression mesh surface 18. Drugs for thrombolysis are arranged in the drug outlet holes 20. A water-based film is provided at the opening of the drug outlet holes 20. When the expansion rod 12 is expanded and the water-based film is dissolved, the drug is integrated into the blood under the flushing of the blood flow, thereby performing thrombolytic treatment on the captured thrombus.

[0056] Here, drug outlet holes 20 which can be filled with thrombolytic drugs are arranged on both sides of the deployment rod 12 which are perpendicular to the compression mesh surface 18. The thrombus received by the compression mesh surface 18 is dissolved by the released thrombolytic drugs. Since the compression mesh surface 18 is arranged on the outer side of the deployment rod 12 when entering the blood vessel, the drug can be prevented from being released prematurely, and the drug can be released again at a specific position to increase the benefit rate, thereby drawing out the thrombus and clearing the blood.

[0057] As a preferred embodiment, medicine storage spaces 21 are provided inside the two ends of the deployment rod 12 away from the connection groove 16 , and the medicine outlet hole 20 is communicated with the medicine storage space 21 .

[0058] Here, drug storage spaces 21 are provided on both sides of the deployment rod 12 at a certain distance from the connecting groove 16, and are connected to the drug outlet hole 20. The setting of the drug storage space 21 ensures that there is enough space in the device to place the thrombolytic agent, thereby avoiding the situation where the aqueous coating dissolves and the agent is released prematurely, resulting in insufficient filled drug and affecting the thrombolytic effect.

[0059] As a preferred embodiment, a communicating hole 7 is provided at the distal end of the first cavity 4 near the movable collar 11 , and the communicating hole 7 is communicated with the second cavity 5 .

[0060] Here, a connecting hole 7 is provided so that the pressure entering the first cavity 4 through the first hole 8 can be discharged, ensuring that the expansion rod 13 is expanded outward to a certain angle and the expansion rod 13 can be closed inward by pressure relief, and the thrombus is compressed by the expansion rod 13 and the compression mesh 18.

[0061] As a preferred implementation, the permanent magnet 3 is loosely matched with the inner wall of the catheter 1 , and the length of the permanent magnet 3 is greater than the inner diameter of the catheter 1 .

[0062] Here, the length of the permanent magnet 3 is set to be larger than the inner diameter of the catheter 1, which can ensure that the permanent magnet 3 moves back and forth in the first cavity 4 without rolling over, and can also ensure that the moving ring 11 has a suitable thrust or pull.

[0063] As a preferred embodiment, the proximal end and distal end of the permanent magnet 3 are respectively connected to the first traction wire 22 and the second traction wire 23, the proximal end of the first traction wire 22 extends out of the first hole 8 along the first cavity 4, and the proximal end of the second traction wire 23 extends out of the second cavity 5 along the second cavity 5.

[0064] Here, by fixing the first traction wire 22 and the second traction wire 23 at both ends of the permanent magnet 3, and the first traction wire 22 passes through the proximal end of the first cavity 4, and the second traction wire 23 passes through the first hole 7 and then passes through the proximal end of the second cavity 5, the proximal ends of the first traction wire 22 and the second traction wire 23 cooperate with the handle at the proximal end of the device to complete the movement of the permanent magnet 3, thereby enabling the umbrella frame 9 to complete the opening and closing action. Here, a shell can be set on the outside of the permanent magnet 3, and the shell is connected to the first traction wire 22 and the second traction wire 23.

[0065] For the embolic protection device that uses pressure to drive the umbrella frame 9 to open. When in use, gas is filled in the first cavity 4 to generate a certain pressure in the cavity, which pushes the permanent magnet 3 to move in the catheter 1 and then drives the movable ring 11 to move and open the umbrella frame 9, wherein the permanent magnet 3 is not constrained in the axial direction of the first cavity 4, and the permanent magnet 3 and the movable ring 11 outside the catheter 1 are on the same plane. When the first cavity 4 is pressurized, the permanent magnet 3 is pushed to move to the far end to reach a preset position, and the pressure is stopped to enter the pressure holding state. At this time, the umbrella frame 9 and the compression mesh surface 18 are in an open state, and the size of the umbrella frame 9 is controlled to adapt to blood vessels with different inner diameters. After the thrombus removal or thrombolysis work is completed, the permanent magnet 3 returns to the initial position due to the reduction of pressure in the first cavity 4, and the umbrella frame 9 shrinks.

[0066] Here, the number of the expansion rods 12 should be determined under the premise of ensuring that the thrombus is controlled and the blood flow is not affected. At the same time, a drug outlet 20 connected to the drug storage space 21 is provided on the expansion rod 13, and a water-soluble film is provided on the end surface of the drug outlet 20 for sealing. After the expansion rod 12 is expanded, the film on the drug outlet 20 dissolves the drug and merges into the blood, and the captured thrombus is subjected to thrombolytic treatment, which can clean the thrombus in the blood vessel more completely and shorten the cleaning time.

[0067] In another embodiment, an embolic protection device is provided that uses traction to drive the umbrella frame 9 to open. When in use, since the proximal and distal ends of the permanent magnet 3 are respectively connected to the first traction wire 22 and the second traction wire 23, the permanent magnet 3 is pulled forward to a preset position by pulling the second traction wire 23 toward the proximal end, and the first traction wire 22 and the second traction wire 23 are fixed at the same time. At this time, the position of the permanent magnet 3 is stable, the umbrella frame 9 and the compression mesh surface 18 are in an open state, and the embolic protection device operates. After the thrombus removal or thrombolysis work is completed, the first traction wire 22 is pulled toward the proximal end, and the permanent magnet 3 returns to the initial position and the umbrella frame 9 is retracted.

[0068] The present invention also provides an embolic protection system, comprising the above embolic protection device and a delivery catheter, wherein the delivery catheter can receive the embolic protection device therein and deliver the embolic protection device.

[0069] Here, the delivery catheter is used to help physicians place the embolic protection device in the blood vessel. The distal end of the delivery catheter is more flexible and the proximal end has better support, which can ensure small bending resistance, good passability and sufficient support, so that the delivery catheter can reach the target position more easily, and then deliver the embolic protection device to the right place, thereby improving the success rate and safety of the interventional surgery. The delivery catheter adopts the existing conventional delivery catheter, and the inner diameter of the delivery catheter is adapted to the outer diameter of the embolic protection device after compression.

[0070] In the present application, the permanent magnet 3 is used to execute the opening and closing of the umbrella frame 9 in the filter assembly 2, but it is not limited to this. The use of an electromagnet to execute the opening and closing of the umbrella frame 9 in the filter assembly 2 also falls within the protection scope of the present application.

[0071] The term "proximal end" generally refers to the end of the corresponding component closer to the operator, and the term "distal end" refers to the end of the corresponding component farther from the operator.

[0072] The above are only preferred embodiments of the present invention and are not intended to limit the present invention. For those skilled in the art, the present invention may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A magnetic embolic protection device, characterized in that: It comprises a catheter (1) and an umbrella-shaped filter assembly (2) arranged on the outer side wall of the distal end of the catheter (1); a permanent magnet (3) is arranged in the catheter (1) to cooperate with the umbrella-shaped filter assembly (2) to open and retract; The catheter (1) is provided with a first cavity (4), a second cavity (5) and a guidewire cavity (6) along its length direction; the first cavity (4) is provided near the inner wall of the catheter (1); the second cavity (5) and the guidewire cavity (6) are provided side by side in the catheter (1); the distal ends of the first cavity (4) and the second cavity (5) are connected to each other via a connecting hole (7); the permanent magnet (3) is placed in the middle of the first cavity (4); the proximal end of the catheter (1) is provided with a first hole (8); the first hole (8) is connected to the first cavity (4).

2. The magnetic embolic protection device according to claim 1, characterized in that: The filter assembly (2) comprises an umbrella frame (9), a fixed ring (10) and a movable ring (11); the fixed ring (10) is fixedly connected to the distal end of the conduit (1), and the fixed ring (10) is fixedly connected to the distal end of the umbrella frame (9); the movable ring (11) is slidably sleeved on the outer wall of the conduit (1), and the movable ring (11) is fixedly connected to the proximal end of the umbrella frame (9); the movable ring (11) and the permanent magnet (3) open and close the umbrella frame (9) through the action of magnetic force.

3. The magnetic embolic protection device according to claim 2, characterized in that: The umbrella stand (9) comprises a plurality of unfolding rods (12) and a plurality of opening rods (13), one end of each of the unfolding rods (12) being rotatably connected to the fixing ring (10) via a first connecting ring, and the unfolding rods (12) being arranged equidistantly on the fixing ring (10), one end of each of the opening rods (13) being rotatably connected to the moving sleeve ring (11) via a second connecting ring (14), and the opening rods (13) being arranged equidistantly on the moving sleeve ring (11), and the other end of the opening rod (13) being rotatably connected to the middle part of the unfolding rod (12) via a limiting shaft (15).

4. The magnetic embolic protection device according to claim 3, characterized in that: A first connecting hole is provided at the free end of the spreading rod (13), a connecting groove (16) is provided in the middle of the unfolding rod (12), the connecting groove (16) matches the spreading rod (13), and second connecting holes (17) are provided on both sides of the connecting groove (16), the first connecting hole and the second connecting hole (17) match the limiting shaft (15).

5. The magnetic embolic protection device according to claim 3, characterized in that: A compression mesh surface (18) is provided on the outer side surface of the expansion rod (12) facing away from the movable sleeve (11); the compression mesh surface (18) is fixedly connected to the expansion rod (12); and a plurality of leakage holes (19) are provided on the compression mesh surface (18) between the expansion rods (12).

6. The magnetic embolic protection device according to claim 5, characterized in that: A plurality of drug outlet holes (20) are provided on two side surfaces of the expansion rod (12) adjacent to the compression mesh surface (18), drugs for thrombolysis are arranged in the drug outlet holes (20), and a water-based coating is provided at the opening of the drug outlet holes (20).

7. The magnetic embolic protection device according to claim 6, characterized in that: Medicine storage spaces (21) are provided inside the two ends of the deployment rod (12) away from the connection groove (16), and the medicine outlet hole (20) is communicated with the medicine storage space (21).

8. The magnetic embolic protection device according to claim 1, characterized in that: The permanent magnet (3) is loosely matched with the inner wall of the catheter (1); the length of the permanent magnet (3) is greater than the inner diameter of the catheter (1).

9. A magnetic embolic protection device according to any one of claims 1 to 8, characterized in that: The proximal end and the distal end of the permanent magnet (3) are respectively connected to a first traction wire (22) and a second traction wire (23); the proximal end of the first traction wire (22) extends out of the first hole (8) along the first cavity (4), and the proximal end of the second traction wire (23) extends out of the second cavity (5) along the second cavity (5).

10. An embolic protection system, characterized in that: The invention comprises the embolic protection device according to any one of claims 1 to 9 and a delivery catheter, wherein the delivery catheter can receive the embolic protection device therein and deliver the embolic protection device.

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