Digital microfluidic driving system and method thereof

Abstract

The invention discloses a digital microfluidics driving system and a method thereof, and relates to the technical field of digital microfluidics, and the method comprises the following steps: S10: selecting a proper power supply input according to an environment, and setting initialization parameters by a graphic visualization software module; s20, the graphic visualization software module outputs the serial data sequence to a low-voltage control circuit; s30, the low-voltage control circuit controls multi-path output of the high-voltage output circuit according to the serial data sequence; s40, connecting a high-voltage output circuit to the electrode array unit array through a spring firing pin; s50, controlling the state of the LE pin of the HV507 chip to carry out data latching and transparent data input; and S60, the control logic of the high-voltage output circuit and the control logic of the low-voltage control circuit are synchronously matched, and the liquid drops are driven to move on the electrode array. The digital micro-fluidic driving system has the beneficial effects that under the condition that the voltage requirement of the digital micro-fluidic driving system is met, the driving capability of the digital micro-fluidic driving system is improved, the driving voltage range, stability and flux are controlled, and the dependence degree of a specific power supply is reduced.

Description

Technical Field

[0001] The present invention relates to the field of digital microfluidic technology, and more specifically, to a digital microfluidic driving system and a method thereof. Background Art

[0002] Digital microfluidics is a new type of droplet manipulation technology that allows the fusion and splitting of single droplets on a digital microfluidic chip to be precisely controlled by a control system. This technology has flourished in the field of biochemistry in recent years, not only promoting the in-depth development of related research, but also improving the efficiency and accuracy of experiments.

[0003] Compared with traditional biochemical detection methods, the electrowetting on dielectric (EWOD) digital microfluidic technology based on electric field drive has higher efficiency and greater automation. At the same time, it also realizes the miniaturization and high integration of the system. Due to its excellent performance, this technology has gradually been widely used in many fields such as biochemical detection and sample synthesis, and has spawned a series of technical derivative products, which not only expand the boundaries of research, but also provide reliable solutions for practical applications. In the research and application of digital microfluidics, addressing technology is currently divided into three types: direct addressing, cross addressing and serial-parallel conversion electrode addressing technology. Each technology has its own unique characteristics and applicable scenarios. The design indicators of digital microfluidic drive systems mainly include volume miniaturization, high voltage regulation capability and high-throughput output capability. Among them, although the direct addressing technology performs well in real-time control, the number of its control lines is too large under high throughput, resulting in a large volume, which is only suitable for low-throughput applications; the cross addressing technology performs well in balancing volume and performance, and is widely used in thin film transistor (TFT) array drive systems. Although various addressing schemes have their own advantages, serial-to-parallel conversion addressing is currently considered to be the best solution for achieving miniaturization and high-throughput output.

[0004] However, although serial-to-parallel conversion addressing technology has been developed in many fields and successfully realized the miniaturization and high-throughput output of digital microfluidic drive systems, there are still some problems that need to be solved. First, the existing digital microfluidic drive systems based on serial-to-parallel conversion face difficulties in compatibility with large voltage input ranges and high-throughput output. Usually, such systems have to make trade-offs in design. Drive systems with large voltage input ranges often have small fluxes, while those with high-throughput capabilities have relatively limited voltage input ranges and low maximum allowable input voltages, which affects the overall performance. Secondly, the current digital microfluidic drive systems based on serial-to-parallel conversion support a relatively single voltage type. Most systems on the market rely on external signal power supplies and can only support DC input, and the input method is single and lacks selectivity. This limitation limits the applicability of the system in different application scenarios and reduces the flexibility and convenience of users.

[0005] In summary, although the development of digital microfluidics has made significant progress, further research and improvement are still needed in terms of voltage compatibility of the driving system and the diversity of input options to meet the ever-changing application needs and promote the continuous development of technology. Summary of the invention

[0006] In order to overcome the shortcomings of the prior art, a digital microfluidic drive system and method are proposed. A low-voltage control circuit controls a high-voltage output circuit, and two high-voltage power supplies are selected to drive an electrode array unit based on a spring striker connection method. While meeting the voltage requirements of the digital microfluidic drive system, the driving capability of the digital microfluidic drive system is improved and the dependence on a specific power supply is reduced.

[0007] The technical solution adopted by the present invention to solve its technical problem is: a digital microfluidic drive system, the improvement of which is that it includes a graphic visualization software module, a low-voltage control circuit, a high-voltage output circuit, an AC-DC rectifier, a DC-DC booster and an electrode array unit;

[0008] The input end of the low-voltage control circuit is connected to the output end of the graphic visualization software module, the output end of the low-voltage control circuit is connected to the input end of the high-voltage output circuit, the output end of the high-voltage output circuit is connected to the input end of the electrode array unit, and the output ends of the AC-DC rectifier and the DC-DC booster are both connected to the high-voltage output circuit; the AC-DC rectifier is used to convert high-voltage alternating current into high-voltage direct current, and the DC-DC booster is used to convert low-voltage direct current into high-voltage direct current; the low-voltage control circuit controls the parallel actual output of the high-voltage output circuit according to the serial data received from the graphic visualization software module, and the high-voltage output circuit is responsible for driving the DC high-voltage drive digital microfluidic electrode array of the droplets to realize the movement of the droplets by the electrowetting effect.

[0009] In the above structure, the low-voltage control circuit includes a signal display circuit and a WIFI module circuit; the main control chip of the signal display circuit is a R7FA4M1AB3CFM chip, and the WIFI module circuit is an ESP32 chip.

[0010] In the above structure, the high-voltage output circuit includes a first HV507 chip and a second HV507 chip, which are cascaded to form a parallel high-voltage output channel, and the serial data input by the low-voltage control circuit changes the on and off of the high-voltage output; the function pin of the first HV507 chip is connected to the input pin of the R7FA4M1AB3CFM chip, and the function pin of the second HV507 chip is connected to the input pin of the R7FA4M1AB3CFM chip.

[0011] In the above structure, the R7FA4M1AB3CFM chip is provided with a DAT_IN1 pin and a DAT_IN2 pin, the DAT_IN1 pin is connected to the DIOB pin of the first HV507 chip, and the DAT_IN2 pin is connected to the DIOA pin of the second HV507 chip.

[0012] In the above structure, a 0 ohm resistor is further provided between the DAT_IN2 pin and the DIOA pin of the second HV507 chip.

[0013] In the above structure, the plurality of electrodes arranged in the electrode array unit array are provided with spring strikers, and each electrode corresponds to a spring striker one-to-one, and the spring striker is connected to the output end of the high-voltage circuit.

[0014] In the above structure, the electrode array unit adopts ball grid array packaging.

[0015] The present invention also discloses a driving method for a digital microfluidic driving system, wherein the method comprises the following steps:

[0016] S10: Select appropriate power input according to the use environment, and set the maximum high voltage channel initialization parameters through the graphic visualization software module;

[0017] S20: the graphic visualization software module outputs the serial data sequence to the low voltage control circuit;

[0018] S30: the low voltage control circuit controls the multiple outputs of the high voltage output circuit according to the serial data sequence;

[0019] S40: The spring striker connects the high-voltage output circuit to the electrode array unit array prepared in advance, one electrode corresponds to one spring striker, and is controlled by one high-voltage channel;

[0020] S50: Control the state of the LE pin of the HV507 chip to perform data latching and transparent data input;

[0021] S60: The high-voltage output circuit is synchronously matched with the control logic of the low-voltage control circuit, so as to achieve synchronous opening of multiple electrodes and drive the droplets to move along a predetermined path on the electrode array.

[0022] Furthermore, the specific steps of step S50 are:

[0023] S501: lowering the LE pin levels of the first HV507 chip and the second HV507 chip, so that the first HV507 chip and the second HV507 chip enter a data latching mode;

[0024] S502: Raise the LE pin levels of the first HV507 chip and the second HV507 chip, and the first HV507 chip and the second HV507 chip enter a transparent data latching mode.

[0025] The beneficial effects of the present invention are: controlling the high-voltage output circuit through a low-voltage control circuit, and driving the electrode array unit based on the spring striker connection method in conjunction with the selection of two high-voltage power supplies, while meeting the voltage requirements of the digital microfluidic drive system, improving the driving capability of the digital microfluidic drive system and reducing the dependence on a specific power supply. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] Figure 1 A schematic diagram of a digital microfluidic drive system of the present invention;

[0027] Figure 2 A flow chart of a driving method of a digital microfluidic driving system of the present invention;

[0028] Figure 3 A schematic diagram of an interface of a graphic visualization software module of a digital microfluidic drive system of the present invention;

[0029] Figure 4 A schematic diagram of a low-voltage control circuit of a digital microfluidic drive system of the present invention;

[0030] Figure 5 A schematic diagram of a high-voltage output circuit of a digital microfluidic drive system of the present invention;

[0031] Figure 6 A schematic diagram of the HV507 data transmission direction and data input port matching of a digital microfluidic drive system of the present invention;

[0032] Figure 7 A schematic diagram of an AC-DC rectifier circuit of a digital microfluidic drive system of the present invention;

[0033] Figure 8 The figure is a schematic diagram of an AC-DC booster circuit of a digital microfluidic drive system of the present invention. DETAILED DESCRIPTION

[0034] The present invention is further described below in conjunction with the accompanying drawings and embodiments.

[0035] The following will clearly and completely describe the concept, specific structure and technical effects of the present invention in combination with the embodiments and drawings, so as to fully understand the purpose, characteristics and effects of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, other embodiments obtained by technicians in this field without creative work are all within the scope of protection of the present invention. In addition, all the connection / connection relationships involved in the patent do not refer to the direct connection of components, but refer to the formation of a better connection structure by adding or reducing connection accessories according to the specific implementation situation. The various technical features in the invention can be combined interchangeably without conflicting with each other.

[0036] In addition, if there are descriptions involving "first", "second", etc. in the embodiments of the present invention, the descriptions of "first", "second", etc. are only used for descriptive purposes and cannot be understood as indicating or suggesting their relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. Secondly, the technical solutions between the various embodiments can be combined with each other, but they must be based on the ability of ordinary technicians in the field to implement them. When the combination of technical solutions is contradictory or cannot be implemented, it should be deemed that such a combination of technical solutions does not exist and is not within the scope of protection required by the present invention.

[0037] See also Figure 1 , the present invention provides a digital microfluidic drive system, including a graphic visualization software module, a low-voltage control circuit, a high-voltage output circuit, an AC-DC rectifier, a DC-DC booster, and an electrode array unit;

[0038] The input end of the low-voltage control circuit is connected to the output end of the graphic visualization software module, the output end of the low-voltage control circuit is connected to the input end of the high-voltage output circuit, the output end of the high-voltage output circuit is connected to the input end of the electrode array unit, and the output ends of the AC-DC rectifier and the DC-DC booster are both connected to the high-voltage output circuit; the AC-DC rectifier is used to convert high-voltage alternating current into high-voltage direct current, and the DC-DC booster is used to convert low-voltage direct current into high-voltage direct current.

[0039] In this embodiment, see Figure 3 As shown, the low-voltage control circuit includes a signal display circuit and a WIFI module circuit; the main control chip of the signal display circuit is a R7FA4M1AB3CFM chip.

[0040] The R7FA4M1AB3CFM chip, based on the ARM Cortex-M4 core, has high-performance processing capabilities while maintaining high computing efficiency in low-power mode. This ensures that the system can respond quickly and effectively manage power consumption during operation, extending the system's working time. The R7FA4M1AB3CFM chip has rich pin configurations and peripheral support, allowing designers to adjust or expand functions as needed. In digital microfluidic systems, different sensors or control modules can be easily expanded to meet more complex droplet operation requirements or environmental detection functions.

[0041] The WIFI module circuit is an ESP32 chip, which integrates WiFi and Bluetooth functions and can achieve low-power wireless communication. Through the WiFi module circuit, the digital microfluidic drive system can perform remote control and data transmission without the need for wired connection to operate and monitor the equipment, thereby improving the flexibility and convenience of the system. The ESP32 chip adopts a dual-core processor architecture with high computing power, while also ensuring a stable wireless connection in low-power mode. For microfluidic systems that require long-term continuous monitoring and control, this not only saves energy but also ensures real-time response of the system. The setting of the R7FA4M1AB3CFM chip and the ESP32 chip improves the output capacity of the low-voltage power supply.

[0042] The graphic visualization software module is a self-developed supporting host computer, which is connected to the computer and the digital microfluidic drive system through a USB interface to power on the low-voltage control circuit; the low-voltage control circuit will control the parallel actual output of the high-voltage output circuit according to the serial data received from the graphic visualization software module, and the high-voltage output circuit is responsible for driving the DC high-voltage drive digital microfluidic electrode array of the droplets to realize the movement of the droplet electrowetting effect. The low-voltage control circuit also includes a MOS tube. After determining the high-voltage power input type, the pulse connected to the gate of the MOS tube can be adjusted through the graphic visualization software module to control the on and off of the MOS tube. The source of the MOS tube outputs a high-voltage unipolar square wave to power two HV507 chips, realizing the unipolar square wave output of the high-voltage output circuit.

[0043] See also Figures 4 to 5 As shown, the high-voltage output circuit includes a first HV507 chip and a second HV507 chip, the first HV507 chip and the second HV507 chip are cascaded to form a parallel high-voltage output channel, and the serial data is input through the low-voltage control circuit to change the opening and closing of the high-voltage output; the function pin of the first HV507 chip is connected to the input pin of the R7FA4M1AB3CFM chip, and the function pin of the second HV507 chip is connected to the input pin of the R7FA4M1AB3CFM chip. The HV507 chip is a high-voltage driver chip, which is usually used to control multi-way high-voltage switches. In the cascade structure, the output of the first HV507 chip is connected to the input of the second HV507, which expands the number of output channels. Each HV507 chip can usually control 64 output channels, so after the first HV507 chip and the second HV507 chip are cascaded, 128 independently controlled high-voltage output channels can be realized. By cascading the first HV507 chip and the second HV507 chip, the system can achieve more high-voltage output channels, which is suitable for application scenarios that require control of multiple high-voltage signals. The control signal of the HV507 chip is transmitted through serial data. The R7FA4M1AB3CFM chip inputs serial data to the HV507 chip through the low-voltage control circuit. These data will control the on or off state of the high-voltage output channel. The method of inputting serial data through the low-voltage control circuit can effectively reduce the number of control lines while maintaining accurate control of the high-voltage switch.

[0044] Furthermore, the R7FA4M1AB3CFM chip is provided with a DAT_IN1 pin and a DAT_IN2 pin, the DAT_IN1 pin is connected to the DIOB pin of the first HV507 chip, and the DAT_IN2 pin is connected to the DIOA pin of the second HV507 chip. The DIOB pin is the serial data input pin of the HV507 chip. Through the DAT_IN1 pin of the R7FA4M1AB3CFM, the first HV507 chip receives serial data from the main control chip. The data is used to control the high-voltage output channel of the first HV507 chip. Through the DAT_IN1 pin, the R7FA4M1AB3CFM chip can directly control the 64 high-voltage output channels in the first HV507 chip. The DIOA pin of the second HV507 chip is connected to the DAT_IN2 pin of the R7FA4M1AB3CFM chip to receive control data. In this way, the 64 high-voltage output channels of the second HV507 chip can also be directly controlled by the R7FA4M1AB3CFM chip. This allows the R7FA4M1AB3CFM chip to simultaneously control a total of 128 high-voltage output channels of the first HV507 chip and the second HV507 chip through two independent data input pins. A 0-ohm resistor is also provided between the DAT_IN2 pin and the DIOA pin of the second HV507 chip. At this time, data transmission can achieve sequential and reverse control of the data movement direction of BABA and ABAB according to the matching relationship between the DIR and DAT_IN1 pins and the DAT_IN2 pins. The 0-ohm resistor is used for circuit debugging. During the debugging or testing phase, the 0-ohm resistor can conveniently disconnect or connect a specific signal path. If it is found in the design that the signal connection needs to be modified or other components need to be introduced, the 0-ohm resistor can be directly removed to reduce the workload of redesigning the PCB.

[0045] The multiple electrodes arranged in the electrode array unit array are arranged in a spring striker, and each electrode corresponds to the spring striker one by one, and the spring striker is connected to the output end of the high-voltage circuit. The spring striker serves as a movable electrical connector, which can reliably transmit the output of the high-voltage circuit to each electrode in the electrode array. Since the spring striker has a certain elastic stroke, it can adapt to different contact surface heights to ensure stable contact between the electrode and the high-voltage circuit. Even if there is a slight mechanical displacement or unevenness between the electrode and the striker, the spring striker can still maintain a reliable electrical connection. The electrode array unit adopts a ball grid array package (BGA), and the BGA package can realize more electrode connection points on a relatively small chip area. Through the ball grid array package, for the electrode array that needs to work at high voltage for a long time, good heat dissipation performance can extend the chip life and make the electrode array have a higher connection density, and it is helpful for the heat dissipation of the chip.

[0046] like Figure 7 and Figure 8 As shown, the AC-DC rectifier is a combination of MB8F bridge rectifier circuit and CBB capacitor filter circuit, and the DC-DC booster is a combination of switching power supply circuit and voltage doubling rectifier circuit using UTC3824 power management chip, and the output voltage is controllable by adjusting the PWM output frequency of the chip. The AC-DC rectifier is used to convert the input high-voltage alternating current (AC) into high-voltage direct current (DC), and the DC-DC booster is used to convert low-voltage direct current into high-voltage direct current. When the high-voltage AC is rectified into a high-voltage DC power supply by the AC-DC rectifier, the other is a low-voltage DC that is boosted into a high-voltage DC power supply by the DC-DC booster. It is connected to the VPP of the HV507 chip through a common terminal. When the use environment is low-voltage input DC, select a DC-DC booster to generate a high-voltage DC power supply, connect the low-voltage input DC and GND to the VCC and GND pins of the DC-DC booster respectively, connect one end of the terminal block to the HVDC of the DC-DC booster, and the other end to HVGND. At this time, you should pay attention to connecting the high-voltage line first before powering on the DC-DC to boost the voltage, otherwise there will be safety hazards in the wiring of the high-voltage output situation; when the use environment is high-voltage AC, select an AC-DC rectifier to generate a high-voltage DC power supply, connect the high-voltage input AC to the AC terminal of the AC-DC rectifier, connect one end of the terminal block to the DC terminal HVDC of the AC-DC rectifier, and the other end to the DC terminal HVGND. At this time, you should pay attention to connecting the high-voltage line first before powering on the DC-DC to boost the voltage, otherwise there will be safety hazards in the wiring of the high-voltage output situation.

[0047] Reference Figure 1-8 As shown, the present invention also discloses a driving method of a digital microfluidic driving system, the improvement of which is that the method comprises the following steps:

[0048] S10: Select appropriate power input according to the use environment, and set the maximum high voltage channel initialization parameters through the graphic visualization software module;

[0049] S20: the graphic visualization software module outputs the serial data sequence to the low voltage control circuit;

[0050] S30: the low voltage control circuit controls the multiple outputs of the high voltage output circuit according to the serial data sequence;

[0051] S40: The spring striker connects the high-voltage output circuit to the electrode array unit array prepared in advance, one electrode corresponds to one spring striker, and is controlled by one high-voltage channel;

[0052] S50: Control the state of the LE pin of the HV507 chip to perform data latching and transparent data input;

[0053] S60: The high-voltage output circuit is synchronously matched with the control logic of the low-voltage control circuit, so as to achieve synchronous opening of multiple electrodes and drive the droplets to move along a predetermined path on the electrode array.

[0054] Furthermore, the specific steps of step S50 are:

[0055] S501: lowering the LE pin levels of the first HV507 chip and the second HV507 chip, so that the first HV507 chip and the second HV507 chip enter a data latching mode;

[0056] S502: Raise the LE pin levels of the first HV507 chip and the second HV507 chip, and the first HV507 chip and the second HV507 chip enter a transparent data latching mode.

[0057] In latch mode, the output of the HV507 chip will maintain its current state and will not be affected by subsequent data changes, ensuring the stability of the high-voltage output on the electrode array. Through data latching, accidental triggering caused by data disturbances or signal fluctuations can be avoided, thereby reducing interference with the droplet path. The R7FA4M1AB3CFM chip controls the first HV507 chip and the second HV507 chip to enter latch mode at the same time, so that multiple electrode channels can be controlled synchronously to achieve multi-channel parallel operation of droplets. In transparent data latch mode, data can be directly transmitted to the output end through the input end, and the output state will follow the changes in the input in real time. During the operation of multiple electrodes, the switch state of the electrode can be adjusted in real time. At this time, the HV507 chip will continue to monitor and process data input to ensure continuous data transmission. Since it has entered the transparent data latch mode, the HV507 chip can also ensure the synchronization and precise transmission of high-voltage control signals.

[0058] In the present invention, the high-voltage output circuit is controlled by a low-voltage control circuit, and the electrode array unit based on the spring striker connection mode is driven in conjunction with the selection of two high-voltage power supplies. Under the condition of meeting the voltage requirements of the digital microfluidic drive system, the driving ability of the digital microfluidic drive system is improved, and the dependence on a specific power supply is reduced. By controlling multiple high-voltage output channels through a low-voltage control circuit, the precise movement of droplets on the electrode array can be achieved. The state of each electrode can be controlled separately to ensure that the droplets move along a predetermined path, thereby improving the accuracy and repeatability of the experiment. This parallel capability greatly improves the processing speed and is suitable for complex microfluidic experiments that require efficient operation. This improvement scheme not only improves the accuracy and efficiency of the operation, but also enhances the reliability and flexibility of the system. Through the introduction of a graphic visualization software module and the application of multi-channel high-voltage control technology, the entire system can adapt to diverse experimental needs, and is an efficient and practical solution in modern microfluidic technology.

[0059] The above is a specific description of the preferred implementation of the present invention, but the invention is not limited to the embodiments. Those skilled in the art can make various equivalent modifications or substitutions without violating the spirit of the present invention. These equivalent modifications or substitutions are all included in the scope defined by the claims of this application.

Claims

1. A digital microfluidic drive system, characterized in that: It includes a graphic visualization software module, a low voltage control circuit, a high voltage output circuit, an AC-DC rectifier, a DC-DC booster, and an electrode array unit; The input end of the low-voltage control circuit is connected to the output end of the graphic visualization software module, the output end of the low-voltage control circuit is connected to the input end of the high-voltage output circuit, the output end of the high-voltage output circuit is connected to the input end of the electrode array unit, and the output ends of the AC-DC rectifier and the DC-DC booster are both connected to the high-voltage output circuit; the AC-DC rectifier is used to convert high-voltage alternating current into high-voltage direct current, and the DC-DC booster is used to convert low-voltage direct current into high-voltage direct current; the low-voltage control circuit controls the parallel actual output of the high-voltage output circuit according to the serial data received from the graphic visualization software module, and the high-voltage output circuit is responsible for driving the DC high-voltage drive digital microfluidic electrode array of the droplets to realize the movement of the droplets by the electrowetting effect.

2. A digital microfluidic drive system according to claim 1, characterized in that: The low-voltage control circuit includes a signal display circuit and a WIFI module circuit; the main control chip of the signal display circuit is a R7FA4M1 AB3CFM chip, and the WIFI module circuit is an ESP32 chip.

3. A digital microfluidic drive system according to claim 2, characterized in that: The high-voltage output circuit includes a first HV507 chip and a second HV507 chip, which are cascaded to form a parallel high-voltage output channel, and the high-voltage output is turned on and off by inputting serial data through a low-voltage control circuit; the function pin of the first HV507 chip is connected to the input pin of the R7FA4M1 AB3CFM chip, and the function pin of the second HV507 chip is connected to the input pin of the R7FA4M1 AB3CFM chip.

4. A digital microfluidic drive system according to claim 2, characterized in that: The R7FA4M1 AB3CFM chip is provided with a DAT_I N1 pin and a DAT_I N2 pin, the DAT_I N1 pin is connected to the DIOB pin of the first HV507 chip, and the DAT_I N2 pin is connected to the DIOA pin of the second HV507 chip.

5. A digital microfluidic drive system according to claim 4, characterized in that: A 0 ohm resistor is also provided between the DAT_I N2 pin and the D IOA pin of the second HV507 chip.

6. A digital microfluidic drive system according to claim 2, characterized in that: The plurality of electrodes arranged in the electrode array unit array are arranged with spring strikers, and each electrode corresponds to a spring striker one by one, and the spring striker is connected to the output end of the high voltage circuit.

7. A digital microfluidic drive system according to claim 1, characterized in that: The electrode array unit adopts ball grid array packaging.

8. A driving method of the digital microfluidic driving system according to any one of claims 1 to 7, characterized in that: The method comprises the following steps: S10: Select appropriate power input according to the use environment, and set the maximum high voltage channel initialization parameters through the graphic visualization software module; S20: the graphic visualization software module outputs the serial data sequence to the low voltage control circuit; S30: the low voltage control circuit controls the multiple outputs of the high voltage output circuit according to the serial data sequence; S40: The spring striker connects the high-voltage output circuit to the electrode array unit array prepared in advance, one electrode corresponds to one spring striker, and is controlled by one high-voltage channel; S50: Control the state of the LE pin of the HV507 chip to perform data latching and transparent data input; S60: The high-voltage output circuit is synchronously matched with the control logic of the low-voltage control circuit, so as to achieve synchronous opening of multiple electrodes and drive the droplets to move along a predetermined path on the electrode array.

9. The driving method of a digital microfluidic driving system according to claim 7, characterized in that: The specific steps of step S50 are: S501: lowering the LE pin levels of the first HV507 chip and the second HV507 chip, so that the first HV507 chip and the second HV507 chip enter a data latching mode; S502: Raise the LE pin levels of the first HV507 chip and the second HV507 chip, and the first HV507 chip and the second HV507 chip enter a transparent data latching mode.

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