Glass slide rotating, aligning and fixing device of optical pathological section scanner

Abstract

The invention relates to the technical field of fixing devices, and particularly discloses a glass slide rotating, aligning and fixing device of an optical pathological section scanner, which comprises a scanner, the scanner comprises a base and a lens arm fixedly mounted at the top of the base, and a lens barrel and an objective table which are distributed up and down are fixedly mounted on the front side of the lens arm. According to the application, the travel that the moving frame continues to move downwards after the mounting frame abuts against the rotating disc is utilized, the extrusion control assembly controls the four L-shaped clamping plates to approach synchronously, four-point constraint is formed on the glass slide, and when the L-shaped clamping plates gradually approach and make contact with the glass slide, the vertical guide alignment unit is arranged on the outer side of the lens barrel. According to the technical scheme, uniform pressure from four directions is applied to the glass slide, and the uniform pressure forces the glass slide to generate tiny displacement in the horizontal direction until the glass slide is centered, so that rotary alignment, accurate centering deviation correction, clamping and fixing of the glass slide are realized, and the glass slide can be positioned right below an objective lens for scanning.

Description

Technical Field

[0001] The invention relates to the technical field of fixing devices, and more specifically, to a glass slide rotation alignment fixing device for an optical pathology slice scanner. Background Art

[0002] Optical pathology slide scanners are used in medical and biological research. They can convert tissue or cell samples on traditional glass slides into high-resolution digital images to improve the diagnostic efficiency and accuracy of doctors, researchers and pathologists. Slides are an indispensable part of using optical pathology slide scanners. They are small transparent glass slides used to carry biological samples. They are usually 76mm x 26mm in size and about 1mm thick. In the process of optical pathology slide scanning, in order to ensure the accurate position of the sample during scanning, the slide needs to be fixed directly under the optical pathology slide scanner for scanning.

[0003] At present, the alignment and fixation methods of slides generally include placement slot fixation, mechanical clamp fixation, magnetic fixation and vacuum adsorption fixation. Among them, the most commonly used is the placement slot type, that is, a special placement slot is provided on the stage. The length of the placement slot matches the standard slide, and the width is larger than the width of the standard slide, ensuring that the slide can be tightly embedded in it for fixation, and the slide can slide back and forth in the horizontal direction for adjustment and alignment. However, this alignment and fixation method still has certain defects:

[0004] 1. After the glass slide is embedded in the placement groove, the placement groove limits the left and right directions of the glass slide, aligns the front and back directions, and maintains stability in the front and back and vertical directions through the friction between the glass slide and the groove wall. However, this fixing method is easily affected by external vibration or impact, causing the glass slide to move slightly in the vertical direction or front and back during scanning. This slight movement may cause image blur or distortion, especially in high-magnification imaging or long-term scanning.

[0005] 2. In the slot-type fixing method, the staff usually observes the position of the slide through the eyepiece and manually slides the slide for alignment. However, even if the staff observes the position of the slide through the eyepiece, the resolution of the human eye is still limited, and it is difficult to accurately judge whether the slide is completely centered. Especially in the case of high-magnification imaging, a slight offset may cause a significant decrease in image quality, and the human eye may not be able to detect these subtle deviations. Summary of the invention

[0006] The present invention provides a slide rotation alignment fixing device for an optical pathology slice scanner, which solves the technical problems in the prior art that a slot-type fixed slide is easily affected by external vibration or impact and the accuracy of the slide adjustment alignment needs to be improved.

[0007] The present invention provides a slide rotation alignment fixing device for an optical pathology slice scanner, comprising a scanner, wherein the scanner comprises a base and a mirror arm fixedly installed on the top of the base, a mirror barrel and a stage distributed up and down are fixedly installed on the front side of the mirror arm, a vertical guide alignment unit is arranged on the outer side of the mirror barrel, a rotation alignment unit and two conveyor belts for carrying and controlling the rotation of the slide are arranged on the top of the stage, the two conveyor belts are symmetrically distributed on both sides of the rotation alignment unit and are respectively used for loading and unloading the slide, a self-centering clamping unit is arranged between the vertical guide alignment unit and the rotation alignment unit, the vertical guide alignment unit comprises a primary driving guide component and a secondary guiding component, and the self-centering clamping unit comprises a moving frame connected to the secondary guiding component, a centering clamping component, an extrusion control component for controlling the centering clamping component, and a locking and pressing component.

[0008] The centering clamping assembly includes a plurality of return springs 1 fixedly installed at the bottom of the moving frame, a mounting frame is installed on the bottom ends of the plurality of return springs 1, four return springs 2 distributed in a rectangular shape are fixedly installed on the inner side of the mounting frame, and an L-shaped clamp is fixedly installed on the adjacent ends of the four return springs 2.

[0009] The vertical guide alignment unit moves downward to control the four L-shaped clamps to synchronously approach and clamp the slide glass through the squeezing control component, and at the same time, the locking pressing component locks the L-shaped clamps, the mounting frame and the moving frame.

[0010] Furthermore, a mounting groove is provided on the top of the loading platform, and the rotation alignment unit includes a rotating shaft rotatably installed on the top of the mounting groove and a rotating disk fixedly installed on the top of the rotating shaft, and the top surface of the rotating disk, the top surface of the loading platform and the top surfaces of the two conveyor belts are all flush with each other.

[0011] Furthermore, the first-level guide assembly includes two guide rails symmetrically installed on the outside of the lens barrel and an electric slider slidably connected to the guide rails, and the second-level guide assembly includes a guide plate fixedly installed on the side of the electric slider away from the guide rails, the left and right guide plates are symmetrical to each other, and the movable frame is fixedly installed at the bottom of the two guide plates.

[0012] Furthermore, guide sleeves are fixedly installed on the rear sides of the two guide plates, and four groups of guide rods distributed in a rectangular shape are fixedly installed on the top of the rotating disk. A single group of guide rods is provided with two symmetrical guide rods. The inner diameter of the guide sleeve is the same as the diameter of the guide rod. When scanning the slide, the two guide sleeves cooperate with the two guide rods located on the rear side.

[0013] Furthermore, the extrusion control assembly includes a sliding rod fixedly mounted on one side of the L-shaped clamping plate close to the mounting frame and slidingly passing through the mounting frame, a driven wedge rod is fixedly mounted on one end of the sliding rod away from the L-shaped clamping plate, and four driving wedge rods distributed in a rectangular shape are fixedly mounted on the bottom of the movable frame, and the four driving wedge rods cooperate with the corresponding driven wedge rods.

[0014] Furthermore, the locking and pressing assembly includes four mounting plates fixedly installed on the inner side of the mounting frame and distributed in a rectangular shape, the four mounting plates are respectively located above the four L-shaped clamps, two mounting rods are fixedly installed on the bottom of the mounting plates, an L-shaped plug-in plate is fixedly installed on the bottom end of the mounting rods, the two L-shaped plug-in plates are perpendicular to each other, and two slots perpendicular to each other are opened on the top of the L-shaped clamp, and the two L-shaped plug-in plates respectively cooperate with the corresponding slots.

[0015] Furthermore, four locking rods with a rectangular distribution are fixedly installed on the bottom of the movable frame, four return springs are respectively mounted on the outside of the corresponding locking rods, a locking circular plate is fixedly installed on the bottom end of the locking rod, and four groups of locking grooves with a rectangular distribution are opened on the top of the rotating disk, each group of locking grooves has four rectangular distributions, the diameter of the locking circular plate is the same as the diameter of the locking grooves, and the four locking circular plates cooperate with the corresponding locking grooves located on the rear side when scanning the slide.

[0016] Furthermore, the centering clamping assembly also includes a limiting rod fixedly mounted on one side of the L-shaped clamping plate close to the mounting frame and slidingly passing through the mounting frame. The limiting rod plays a limiting role during the movement of the L-shaped clamping plate to prevent the L-shaped clamping plate from twisting.

[0017] Furthermore, four baffles in a rectangular distribution are fixedly installed on the top of the rotating disk, and four groups of rollers in a rectangular distribution are rotatably installed on the top of the rotating disk. Each group of rollers is provided with three pairs and is driven by an external power supply. The left conveyor belt transports the slide to the right and it abuts against the baffle under the conveyance of the roller and waits for rotation alignment.

[0018] Furthermore, a condenser located below the stage is fixedly mounted on the front side of the lens arm, and an eyepiece and an objective lens are fixedly mounted on both ends of the lens barrel, respectively, and the eyepiece is located above the objective lens.

[0019] The beneficial effects of the present invention are:

[0020] 1. The present application utilizes the travel of the movable frame continuing to move downward after the mounting frame resists the rotating disk, and controls the four L-shaped clamps to approach synchronously through the extrusion control component, thereby forming a four-point constraint on the glass slide. When the L-shaped clamps gradually approach and contact the glass slide, uniform pressure is applied to the glass slide from four directions. This uniform pressure forces the glass slide to make a slight displacement in the horizontal direction until the glass slide is centered, thereby realizing rotational alignment, precise centering and correction, clamping and fixing of the glass slide, so that the glass slide can be located directly below the objective lens for scanning, thereby improving the scanning accuracy.

[0021] 2. In the present application, after clamping the glass slide, a locking mechanism can be formed by inserting a locking circular plate into the locking groove, thereby effectively locking the position of the movable frame to prevent it from moving due to external vibration or other factors during scanning, causing the glass slide to shift. At the same time, the L-shaped pressure plate inserted into the slot will also press the four corners of the slide to ensure that the slide does not move or shift slightly during the scanning process. This double clamping mechanism fixes and locks the slide in all directions in the XYZ axis direction, providing a higher clamping force, which is particularly suitable for scanning scenarios that require high-precision imaging. After the L-shaped pressure plate is inserted into the slot, the position of the L-shaped clamp is also fixed to prevent the L-shaped clamp from loosening due to external vibration or other factors during scanning, thereby further improving the clamping stability of the slide.

[0022] 3. The present application performs dual guidance on the moving frame and the mounting frame during the downward movement of the moving frame. The dual guidance mechanism ensures that the moving frame and the mounting frame maintain a stable motion trajectory during the descent process, so that the clamping center of the centering clamping assembly can always remain concentric with the lens barrel and the objective lens located at the rear side, thereby ensuring that subsequent centering clamping can be more precise. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 It is a three-dimensional structural schematic diagram of the present invention.

[0024] Figure 2 The present invention Figure 1 A partial enlarged view of part A.

[0025] Figure 3 It is a schematic diagram of the three-dimensional structure of the rotating disk, slide glass, locking groove, roller and baffle part of the present invention.

[0026] Figure 4 It is an exploded view of the three-dimensional structure of the movable frame, the mounting frame, the first return spring, the second return spring and the L-shaped clamping plate of the present invention.

[0027] Figure 5 It is a partial three-dimensional structural schematic diagram of the self-centering clamping unit of the present invention.

[0028] Figure 6It is a partial three-dimensional structural schematic diagram of the return spring 1, the mounting frame, the return spring 2 and the L-shaped clamping plate of the present invention.

[0029] In the figure: 1. scanner; 101. base; 102. mirror arm; 103. stage; 104. mirror tube; 105. eyepiece; 106. objective lens; 107. condenser; 2. conveyor belt; 3. baffle; 4. rotation alignment unit; 5. vertical guide alignment unit; 6. self-centering clamping unit; 7. roller; 8. slide; 401. rotating shaft; 402. rotating disk; 501. primary guide assembly; 502. secondary guide assembly; 5011. guide rail; 5012. electric slider; 5021. guide plate; 5022. guide sleeve; 5023 , guide rod; 601, moving frame; 602, centering clamping assembly; 603, extrusion control assembly; 604, locking and pressing assembly; 6021, reset spring one; 6022, mounting frame; 6023, reset spring two; 6024, L-shaped clamping plate; 6025, limit rod; 6031, driving wedge rod; 6032, sliding rod; 6033, driven wedge rod; 6041, mounting plate; 6042, mounting rod; 6043, L-shaped plug-in plate; 6044, slot; 6045, locking rod; 6046, locking circular plate; 6047, locking groove. DETAILED DESCRIPTION

[0030] The subject matter described herein will now be discussed with reference to example embodiments. It should be understood that the discussion of these embodiments is to enable those skilled in the art to better understand and implement the subject matter described herein. The functions and arrangements of the elements discussed may be changed without departing from the scope of protection of the present specification. Various examples may omit, replace or add various processes or components as needed. In addition, the features described relative to some examples may also be combined in other examples.

[0031] See also Figure 1 , Figure 3 and Figure 5In this embodiment, a slide rotation alignment fixing device of an optical pathology slice scanner is proposed, comprising a scanner 1, wherein the scanner 1 comprises a base 101 and a mirror arm 102 fixedly mounted on the top of the base 101, a lens barrel 104 and a stage 103 distributed up and down are fixedly mounted on the front side of the mirror arm 102, a condenser 107 located below the stage 103 is fixedly mounted on the front side of the mirror arm 102, an eyepiece 105 and an objective lens 106 are respectively arranged at both ends of the lens barrel 104, and the eyepiece 105 is located above the objective lens 106, a vertical guide alignment unit 5 is arranged on the outer side of the lens barrel 104, and a vertical guide alignment unit 5 is arranged on the top of the stage 103 A rotation alignment unit 4 and two conveyor belts 2 for carrying and controlling the rotation of the glass slide 8 are provided. The two conveyor belts 2 are symmetrically distributed on both sides of the rotation alignment unit 4 and are respectively used for loading and unloading the glass slide 8. A self-centering clamping unit 6 is provided between the vertical guide alignment unit 5 and the rotation alignment unit 4. The vertical guide alignment unit 5 includes a primary guide component 501 and a secondary guide component 502. The self-centering clamping unit 6 includes a moving frame 601 connected to the secondary guide component 502, a centering clamping component 602, an extrusion control component 603 for controlling the centering clamping component 602, and a locking and pressing component 604.

[0032] See also Figure 1 and Figure 3 The top of the loading platform 103 is provided with a mounting groove, and the rotation alignment unit 4 includes a rotating shaft 401 rotatably mounted on the top of the mounting groove and a rotating disk 402 fixedly mounted on the top of the rotating shaft 401. The rotating shaft 401 is connected to an external power supply. The top surface of the rotating disk 402, the top surface of the loading platform 103 and the top surfaces of the two conveyor belts 2 are all flush with each other. Four baffles 3 distributed in a rectangular manner are fixedly mounted on the top of the rotating disk 402. Four groups of rollers 7 distributed in a rectangular manner are rotatably mounted on the top of the rotating disk 402. Each group of rollers 7 is provided with There are three pairs of them and they are driven by an external power supply. The conveyor belt 2 on the left side conveys the glass slide 8 to the right and makes the glass slide 8 abut against the baffle 3 under the conveyance of the roller 7, and then waits for rotation and alignment. Three objective lenses 106 are arranged on the circumference and are rotatably connected to the lens barrel 104 through an adjusting disk, and the objective lens 106 located on the rear side is concentric with the lens barrel 104, and the angle between two adjacent objective lenses 106 is 120°. The objective lens 106 concentric with the lens barrel 104 can be switched by rotating the adjusting disk. The objective lens 106 concentric with the lens barrel 104 is the objective lens 106 used for scanning.

[0033] See also Figure 1 and Figure 3The first-level driving guide assembly 501 includes two guide rails 5011 symmetrically installed on the outside of the lens barrel 104 and an electric slider 5012 slidably connected to the guide rails 5011. The second-level guiding assembly 502 includes a guide plate 5021 fixedly installed on the side of the electric slider 5012 away from the guide rails 5011. The left and right guide plates 5021 are symmetrical to each other, and the moving frame 601 is fixedly installed at the bottom of the two guide plates 5021.

[0034] See also Figure 1 , Figure 3 and Figure 5 , guide sleeves 5022 are fixedly installed on the rear sides of the two guide plates 5021, four groups of guide rods 5023 with rectangular distribution are fixedly installed on the top of the rotating disk 402, and a single group of guide rods 5023 is provided with two symmetrical ones. The inner diameter of the guide sleeve 5022 is the same as the diameter of the guide rod 5023. When scanning the slide 8, the two guide sleeves 5022 cooperate with the two guide rods 5023 located at the rear side at this time. The centering clamping assembly 602 includes a plurality of return springs 6021 fixedly installed at the bottom of the moving frame 601, and the bottom ends of the plurality of return springs 6021 are jointly installed with a mounting frame 6022.

[0035] When in use, the pathological section slide 8 to be scanned is first conveyed to the right by the conveyor belt 2 on the left and moved through the roller 7 to abut against the baffle 3 on the left, and then the rotating shaft 401 is driven by an external power supply to rotate 90° clockwise, driving the slide 8 abutting against the baffle 3 on the left to rotate 90° clockwise, thereby driving the slide 8 to move to the bottom of the objective lens 106 which is concentric with the lens barrel 104 at this time (that is, the objective lens 106 located at the rear side at this time), but due to the inertial force during the rotation process, the slide 8 may produce a small deviation, causing the slide 8 to deviate from the bottom of the objective lens 106 at the rear side at this time, and then the electric slider 5012 is controlled to move downward along the guide rail 5011, so that the left and right electric sliders 5012 move downward synchronously, thereby driving the two guide plates 502 1 moves downward, thereby driving the moving frame 601 to move downward, so that the mounting frame 6022 moves downward accordingly, and as the moving frame 601 gradually moves downward, the guide sleeve 5022 will be slidably sleeved on the outer side of the guide rod 5023 and continue to move downward under the guidance of the guide rod 5023, thereby forming a double guide for the moving frame 601 and the mounting frame 6022. The double guide mechanism ensures that the moving frame 601 and the mounting frame 6022 maintain a stable motion trajectory during the descending process, so that the clamping center of the centering clamping assembly 602 can always be concentric with the lens barrel 104 and the objective lens 106 located at the rear side, thereby ensuring that the subsequent centering clamping can be more accurate. When the mounting frame 6022 conflicts with the rotating disk 402, the centering clamping assembly 602 is distributed outside the four right-angled edges of the slide glass 8.

[0036] See also Figure 2, Figure 4 , Figure 5 and Figure 6 The centering clamping assembly 602 also includes four return springs 6023 fixedly installed on the inner side of the mounting frame 6022 and distributed in a rectangular shape. An L-shaped clamping plate 6024 is fixedly installed at one end thereof. A silicone anti-slip pad is provided on the inner side of the L-shaped clamping plate 6024, which can gently clamp the glass slide 8 when clamping the glass slide 8 to avoid physical damage to the glass slide 8.

[0037] See also Figure 2 , Figure 4 , Figure 5 and Figure 6 The centering clamping assembly 602 also includes a limiting rod 6025 fixedly mounted on the L-shaped clamping plate 6024 near the mounting frame 6022 and slidingly passing through the mounting frame 6022. The limiting rod 6025 plays a limiting role during the movement of the L-shaped clamping plate 6024 to prevent the L-shaped clamping plate 6024 from twisting.

[0038] See also Figure 2 , Figure 4 , Figure 5 and Figure 6 The extrusion control assembly 603 includes a slide rod 6032 fixedly mounted on the side of the L-shaped clamp plate 6024 close to the mounting frame 6022 and slidingly passing through the mounting frame 6022. A driven wedge rod 6033 is fixedly mounted on the end of the slide rod 6032 away from the L-shaped clamp plate 6024. Four driving wedge rods 6031 distributed in a rectangular shape are fixedly mounted on the bottom of the movable frame 601. The four driving wedge rods 6031 cooperate with the corresponding driven wedge rods 6033.

[0039] When in use, after the mounting frame 6022 contacts the rotating disk 402, the moving frame 601 continues to move and starts to compress the return spring 1 6021, and drives the driving wedge rod 6031 to continue to move downward, and squeezes the driven wedge rod 6033, so that the driven wedge rod 6033 drives the L-shaped clamping plate 6024 to slide toward the side close to the slide glass 8 under the limit of the limit rod 6025 through the sliding rod 6032, so that the four L-shaped clamping plates 6024 synchronously approach the slide glass 8 and stretch the return spring 2 6023. As the L-shaped clamping plates 6024 gradually approach the slide glass 8, the four L-shaped clamping plates 6024 are The L-shaped clamps 6024 are respectively located on the outside of the four right-angled sides of the glass slide 8, forming a "four-point constraint" system. When the L-shaped clamps 6024 gradually approach and contact the glass slide 8, they will apply uniform pressure to the glass slide 8 from four directions. This uniform pressure will force the glass slide 8 to make a slight displacement in the horizontal direction until the glass slide 8 is centered (that is, adjusted to a position directly below the rear objective lens 106), thereby realizing rotational alignment, precise centering and correction, clamping and fixing of the glass slide 8, so that the glass slide 8 can be located directly below the objective lens 106 for scanning.

[0040] See also Figure 2 , Figure 4 , Figure 5 and Figure 6 The locking and pressing assembly 604 includes four mounting plates 6041 fixedly installed on the inner side of the mounting frame 6022 and distributed in a rectangular shape. The four mounting plates 6041 are respectively located above the four L-shaped clamping plates 6024. Two mounting rods 6042 are fixedly installed on the bottom of the mounting plates 6041. An L-shaped plug-in plate 6043 is fixedly installed on the bottom end of the mounting rod 6042. The two L-shaped plug-in plates 6043 are perpendicular to each other. Two slots 6044 perpendicular to each other are opened on the top of the L-shaped clamping plate 6024. The two L-shaped plug-in plates 6043 are respectively matched with the corresponding slots 6044.

[0041] See also Figure 2 , Figure 3 , Figure 5 and Figure 6 Four rectangularly distributed locking rods 6045 are fixedly installed at the bottom of the movable frame 601, and four return springs 6021 are respectively sleeved on the outside of the corresponding locking rods 6045. A locking circular plate 6046 is fixedly installed at the bottom of the locking rod 6045. Four groups of rectangularly distributed locking grooves 6047 are opened on the top of the rotating disk 402. Each group of locking grooves 6047 is four rectangularly distributed. The diameter of the locking circular plate 6046 is the same as the diameter of the locking groove 6047. When scanning the slide 8, the four locking circular plates 6046 cooperate with the corresponding locking grooves 6047 located on the rear side at this time.

[0042] During specific use, after clamping and fixing the glass slide 8, the movable frame 601 continues to move downward, thereby continuing to drive the mounting rod 6042 and the locking rod 6045 to move downward, so that the L-shaped plug-in plate 6043 and the locking circular plate 6046 continue to move downward, until the L-shaped plug-in plate 6043 is inserted into the slot 6044. After the locking circular plate 6046 is inserted into the locking groove 6047, the electric slider 5012 stops moving, so that the movable frame 601 also stops moving. At this time, the locking circular plate 6046 is inserted into the locking groove 6047 to form a locking mechanism, which effectively locks the position of the movable frame 601, ensuring that the movable frame 601 remains stationary during the entire scanning process, preventing it from rebounding or moving due to external vibration or other factors during the scanning process, causing the glass slide 8 to deviate. Especially in the case of high-magnification imaging or long-term scanning, the stability of the glass slide 8 is very important Any slight displacement may affect the quality of the image. At the same time, the L-shaped pressure plate 6043 inserted into the slot 6044 will also press the four corners of the slide 8 to ensure that the slide 8 will not move or deviate slightly during the scanning process. This double clamping mechanism (L-shaped clamping plate 6024 and L-shaped pressure plate 6043) fixes and locks the slide 8 in all directions in the XYZ axis direction, providing a higher clamping force, which is particularly suitable for scanning scenarios that require high-precision imaging. After the L-shaped pressure plate 6043 is inserted into the slot 6044, it not only presses the slide 8, but also fixes the position of the L-shaped clamping plate 6024 to prevent the L-shaped clamping plate 6024 from loosening due to external vibration or other factors during the scanning process, thereby further improving the clamping stability of the slide 8. Finally, the pathological section on the top of the slide 8 is scanned through the objective lens 106.

[0043] After the scanning is completed, the electric slider 5012 is controlled to move upward to reset. As the electric slider 5012 moves upward to reset the movable frame 601, the pressure on the reset spring 1 6021 is reduced and gradually stretched. At the same time, the locking rod 6045, the locking circular plate 6046 and the L-shaped plug-in plate 6043 move upward synchronously to reset until the reset spring 1 6021 is completely reset. The driving wedge rod 6031 also moves upward synchronously in this process and gradually separates from the driven wedge rod 6033, so that the reset spring 2 6023 is gradually reset, driving the L-shaped clamping plate 6024 and The driven wedge rod 6033 is reset to release the L-shaped clamp 6024 from clamping the glass slide 8. Finally, the movable frame 601 continues to move upward, which will drive the mounting frame 6022 to move upward and disengage from the rotating disk 402. Then, the rotating shaft 401 is driven to rotate by an external power supply, driving the rotating disk 402 to rotate 90° clockwise to rotate the scanned glass slide 8 to the right side of the rotating disk 402. Then, the roller 7 on the right side is driven to rotate by an external power supply, driving the scanned glass slide 8 to be transported to the top of the conveyor belt 2 on the right, and the glass slide 8 is transported and discharged by the conveyor belt 2 on the right.

[0044] It should be noted that after the movable frame 601 is reset, the movable frame 601 will be mounted on the outside of the objective lens 106 on the rear side, and the two objective lenses 106 on the front side will be located on the outside of the movable frame 601. During scanning, the movable frame 601 is located below the three objective lenses 106. At this time, if the objective lens 106 needs to be rotated and adjusted, the movable frame 601 will not cause any obstruction.

[0045] Finally, it should be noted that: Obviously, the above embodiments are only examples for clearly explaining the present invention, and are not intended to limit the implementation methods. For ordinary technicians in the relevant field, other different forms of changes or modifications can be made based on the above description. It is not necessary and impossible to list all the implementation methods here. The obvious changes or modifications derived from this are still within the scope of protection of the present invention.

Claims

1. A slide rotation alignment fixing device for an optical pathology section scanner, characterized in that: include: A scanner (1), the scanner (1) comprising a base (101) and a mirror arm (102) fixedly mounted on the top of the base (101); a mirror barrel (104) and a stage (103) arranged vertically are fixedly mounted on the front side of the mirror arm (102); a vertical guide alignment unit (5) is arranged on the outer side of the mirror barrel (104); a rotation alignment unit (4) and two conveyor belts (2) are arranged on the top of the stage (103) for carrying and controlling the rotation of a glass slide (8); the two conveyor belts (2) are symmetrically distributed on both sides of the rotation alignment unit (4) and are respectively used for loading and unloading the glass slide (8); A self-centering clamping unit (6) is provided between the vertical guiding alignment unit (5) and the rotating alignment unit (4), wherein the vertical guiding alignment unit (5) comprises a primary guide assembly (501) and a secondary guide assembly (502), and the self-centering clamping unit (6) comprises a moving frame (601) connected to the secondary guide assembly (502), a centering clamping assembly (602), an extrusion control assembly (603) for controlling the centering clamping assembly (602), and a locking and pressing assembly (604); The centering clamping assembly (602) comprises a plurality of return springs (6021) fixedly mounted on the bottom of the moving frame (601); a mounting frame (6022) is commonly mounted on the bottom ends of the plurality of return springs (6021); four return springs (6023) distributed in a rectangular shape are fixedly mounted on the inner side of the mounting frame (6022); and an L-shaped clamping plate (6024) is fixedly mounted on the adjacent ends of the four return springs (6023); The vertical guide alignment unit (5) moves downward to control the four L-shaped clamping plates (6024) to synchronously approach and clamp the glass slide (8) through the squeezing control component (603), and at the same time, the locking and pressing component (604) locks the L-shaped clamping plates (6024), the mounting frame (6022) and the moving frame (601).

2. The slide rotation alignment fixing device of an optical pathology section scanner according to claim 1, characterized in that: A mounting groove is provided on the top of the loading platform (103), and the rotation alignment unit (4) comprises a rotating shaft (401) rotatably mounted on the top of the mounting groove and a rotating disk (402) fixedly mounted on the top of the rotating shaft (401), and the top surface of the rotating disk (402), the top surface of the loading platform (103) and the top surfaces of the two conveyor belts (2) are all flush with each other.

3. The slide rotation alignment fixing device of an optical pathology section scanner according to claim 1, characterized in that: The primary guide assembly (501) comprises two guide rails (5011) symmetrically mounted on the outside of the lens barrel (104) and an electric slider (5012) slidably connected to the guide rails (5011); the secondary guide assembly (502) comprises a guide plate (5021) fixedly mounted on a side of the electric slider (5012) away from the guide rails (5011); the left and right guide plates (5021) are symmetrical to each other; and the moving frame (601) is fixedly mounted on the bottom of the two guide plates (5021).

4. The slide rotation alignment fixing device of an optical pathology section scanner according to claim 3, characterized in that: A guide sleeve (5022) is fixedly mounted on the rear side of the two guide plates (5021); four groups of guide rods (5023) distributed in a rectangular shape are fixedly mounted on the top of the rotating disk (402); a single group of guide rods (5023) is provided with two mutually symmetrical ones; the inner diameter of the guide sleeve (5022) is the same as the diameter of the guide rod (5023); and the two guide sleeves (5022) cooperate with the two guide rods (5023) located on the rear side when scanning the glass slide (8).

5. The slide rotation alignment fixing device of an optical pathology section scanner according to claim 2, characterized in that: The extrusion control assembly (603) includes a slide bar (6032) fixedly mounted on a side of an L-shaped clamping plate (6024) close to a mounting frame (6022) and slidingly passing through the mounting frame (6022); a driven wedge rod (6033) is fixedly mounted on one end of the slide bar (6032) away from the L-shaped clamping plate (6024); four driving wedge rods (6031) distributed in a rectangular shape are fixedly mounted on the bottom of the movable frame (601); the four driving wedge rods (6031) cooperate with the corresponding driven wedge rods (6033).

6. The slide rotation alignment fixing device of an optical pathology section scanner according to claim 5, characterized in that: The locking and pressing assembly (604) comprises four mounting plates (6041) fixedly mounted on the inner side of the mounting frame (6022) and arranged in a rectangular shape. The four mounting plates (6041) are respectively located above the four L-shaped clamping plates (6024). Two mounting rods (6042) are fixedly mounted on the bottom of the mounting plates (6041). An L-shaped plug-in plate (6043) is fixedly mounted on the bottom end of the mounting rod (6042). The two L-shaped plug-in plates (6043) are perpendicular to each other. Two slots (6044) perpendicular to each other are opened on the top of the L-shaped clamping plate (6024). The two L-shaped plug-in plates (6043) are respectively matched with the corresponding slots (6044).

7. The slide rotation alignment fixing device of an optical pathology section scanner according to claim 5, characterized in that: Four rectangularly distributed locking rods (6045) are fixedly installed at the bottom of the movable frame (601), four return springs (6021) are respectively sleeved on the outside of the corresponding locking rods (6045), and a locking circular plate (6046) is fixedly installed at the bottom of the locking rod (6045). Four groups of rectangularly distributed locking grooves (6047) are opened on the top of the rotating disk (402), and each group of locking grooves (6047) is four rectangularly distributed. The diameter of the locking circular plate (6046) is the same as the diameter of the locking groove (6047). When scanning the slide glass (8), the four locking circular plates (6046) cooperate with the corresponding locking grooves (6047) located at the rear side at this time.

8. The slide rotation alignment fixing device of an optical pathology section scanner according to claim 5, characterized in that: The centering clamping assembly (602) further comprises a limiting rod (6025) fixedly mounted on a side of the L-shaped clamping plate (6024) close to the mounting frame (6022) and slidingly passing through the mounting frame (6022); the limiting rod (6025) serves to limit the movement of the L-shaped clamping plate (6024) and prevent the L-shaped clamping plate (6024) from twisting.

9. The slide rotation alignment fixing device of an optical pathology section scanner according to claim 2, characterized in that: Four baffles (3) arranged in a rectangular shape are fixedly mounted on the top of the rotating disk (402). Four groups of rollers (7) arranged in a rectangular shape are rotatably mounted on the top of the rotating disk (402). Each group of rollers (7) is provided with three pairs and is driven by an external power supply. The left conveyor belt (2) conveys the glass slide (8) to the right and abuts against the baffle (3) under the conveyance of the rollers (7) to wait for rotation alignment.

10. The slide rotation alignment fixing device of an optical pathology section scanner according to claim 1, characterized in that: A condenser (107) located below the stage (103) is fixedly mounted on the front side of the lens arm (102); an eyepiece (105) and an objective lens (106) are respectively arranged at both ends of the lens barrel (104), and the eyepiece (105) is located above the objective lens (106).

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