Source distribution system for implanted particles, display system for implanted particles, device and medium

Abstract

The invention relates to a source distribution system for implanted particles, a display system for implanted particles, equipment and a medium. The source distribution system comprises a processor, and the processor is used for acquiring a medical image of an intervention object; extracting at least one target area from the medical image; in response to the user operation, determining a target mode applied to at least one target area from a plurality of preset source distribution modes; the source distribution mode is a mode of performing particle source distribution on the intervention object through control operation of a user and / or program control of a particle source distribution system; based on the target mode, performing particle source distribution processing on the at least one target area to obtain a source distribution result; and the particle source distribution processing is used for configuring an implantation track and spatial distribution of the radioactive particles when the radioactive particles are implanted into the interventional object. By the adoption of the source distribution system, the particle source distribution efficiency can be effectively improved, the accuracy and feasibility of source distribution of implanted particles are improved, and more reference information is provided for subsequent medical treatment.

Description

Technical Field

[0001] This application relates to the field of medical imaging technology, and particularly to a radioactive seed source distribution system, a radioactive seed display system, a radioactive seed source distribution method, a radioactive seed display method, a computer device, a storage medium, and a computer program product for implanting radioactive seeds. Background Art

[0002] The radioactive seed implantation treatment technology is mainly based on the examination results of the patient's ultrasound, CT, MRI and other images, and uses a radioactive seed treatment planning system (TPS) to distribute the implantation trajectory and orientation of the radioactive seeds when implanted into the patient's body, as well as the number and position of the seeds, so as to plan a treatment plan.

[0003] However, in the current process of planning treatment plans, it is quite dependent on the professional experience of physicians. Usually, after manually examining the patient's examination results by a physician, the implantation of radioactive seeds is manually drawn on the examination images, resulting in low efficiency and inaccurate radioactive seed distribution, which is not conducive to the effect of medical treatment. Summary of the Invention

[0004] Based on this, in view of the above technical problems, it is necessary to provide a radioactive seed source distribution system, a radioactive seed display system, a radioactive seed source distribution method, a radioactive seed display method, a computer device, a storage medium, and a computer program product that can improve the efficiency and accuracy of radioactive seed distribution.

[0005] In a first aspect, this application provides a radioactive seed source distribution system. The system includes a processor, and the processor is configured to:

[0006] Obtain a medical image of an intervention object;

[0007] Extract at least one target area from the medical image;

[0008] In response to a user operation, determine a target mode applied to the at least one target area from a plurality of preset source distribution modes; the source distribution mode is a method of distributing radioactive seeds to the intervention object through the user's control operation and / or the program control of the radioactive seed source distribution system;

[0009] Based on the target mode, perform radioactive seed source distribution processing on the at least one target area to obtain a source distribution result; the radioactive seed source distribution processing is used to configure the implantation trajectory and spatial distribution of the radioactive seeds when implanted into the intervention object.

[0010] In one embodiment, the source distribution mode includes a first mode;

[0011] In terms of performing particle source distribution processing on the at least one target area based on the target pattern, the processor is configured to:

[0012] When the target pattern is the first pattern, in response to the program control of the particle source distribution system, based on a preset source distribution rule, configure multiple sets of trajectory information and corresponding and matched multiple sets of particle information for the at least one target area;

[0013] Determine target trajectory information and corresponding and matched target particle information from the multiple sets of trajectory information and corresponding and matched multiple sets of particle information.

[0014] In one embodiment, the source distribution pattern includes a second pattern;

[0015] In terms of performing particle source distribution processing on the at least one target area based on the target pattern, the processor is configured to:

[0016] When the target pattern is the second pattern, in response to the control operation of the user, configure trajectory information for the at least one target area;

[0017] In response to the program control of the particle source distribution system, based on a preset source distribution rule and the trajectory information, configure particle information for the at least one target area.

[0018] In one embodiment, the source distribution pattern includes a third pattern;

[0019] In terms of performing particle source distribution processing on the at least one target area based on the target pattern, the processor is configured to:

[0020] When the target pattern is the third pattern, based on the annotation operation of the user on the at least one target area, divide at least one annotation area in the target area, and annotate corresponding annotation content in the at least one annotation area;

[0021] For the unannotated area in the target area, in response to the program control of the particle source distribution system, based on a preset source distribution rule, configure trajectory information and particle information for the unannotated area; and

[0022] For the at least one annotation area, in response to the control operation of the user and / or the program control of the particle source distribution system, based on the annotation content, configure trajectory information and particle information for the annotation area.

[0023] In one embodiment, in terms of configuring corresponding trajectory information and particle information based on a preset source distribution rule, the processor is configured to:

[0024] Based on the target points in the target region, multiple candidate implantation trajectories for the target region are obtained;

[0025] Under the limitation of a preset first constraint condition, based on the volume, spatial position of the target region, and the target skin distances of the respective candidate implantation trajectories, at least one target implantation trajectory is screened out from the multiple candidate trajectories to obtain corresponding trajectory information;

[0026] Under the limitation of a preset second constraint condition, based on the volume, the spatial position, and the trajectory information, corresponding particle information is configured; the particle information is used to characterize the spatial distribution of the radioactive particles when implanted into the intervention object.

[0027] In one embodiment, the target region is a first type of tissue region in the intervention object that is marked and spans multiple object cross-sections, and the intervention object further includes a second type of tissue region that is marked and spans multiple object cross-sections;

[0028] In terms of screening out at least one target implantation trajectory that meets the constraint conditions, the processor is configured to:

[0029] Under the limitation of the first constraint condition, screen out at least one target implantation trajectory from the candidate implantation trajectories;

[0030] Wherein, the first constraint condition includes a first sub-constraint condition, a second sub-constraint condition, and a third sub-constraint condition;

[0031] The first sub-constraint condition is used to limit the cross-layer angle of the trajectory direction of the target implantation trajectory when spanning object cross-sections in different plane layers to be less than or equal to a preset angle;

[0032] The second sub-constraint condition is used to limit the trajectory length of the target implantation trajectory to be less than or equal to a preset length;

[0033] The third sub-constraint condition is used to limit the distance between the target implantation trajectory and the second type of tissue region to be greater than or equal to a preset distance.

[0034] In one embodiment, in terms of configuring the corresponding particle information, the processor is configured to:

[0035] Under the limitation of the second constraint condition, configure the particle positions, particle numbers, particle types, and particle activities of the radioactive particles in the at least one implantation trajectory;

[0036] Wherein, the second constraint condition includes a fourth sub-constraint condition, a fifth sub-constraint condition, and a sixth sub-constraint condition;

[0037] The fourth sub-constraint condition is used to limit the distance between the radiation range corresponding to the radioactive particle and the second type of tissue region to be greater than or equal to a preset distance;

[0038] The fifth sub-constraint condition is used to limit the distance between two adjacent radioactive particles to be greater than or equal to a preset distance;

[0039] The sixth sub-constraint condition is used to limit the particle activity to be less than or equal to a preset activity.

[0040] In a second aspect, the present application further provides a display system for implanted particles. The system includes a processor, and the processor is configured to:

[0041] Display a medical image of an intervention object;

[0042] In response to an image recognition and image segmentation operation on the medical image, segment at least one target region from the medical image;

[0043] In response to a selection operation for a target source distribution pattern corresponding to the at least one target region, based on the target source distribution pattern, perform particle source distribution processing on the at least one target region to obtain a source distribution result; the target source distribution pattern is a method of performing particle source distribution on the intervention object through a user's control operation and / or program control of a particle source distribution system; the particle source distribution processing is used to configure the implantation trajectory and spatial distribution of radioactive particles when implanting the intervention object;

[0044] In the medical image, display the source distribution result corresponding to the at least one target region.

[0045] In one embodiment, at least one set of particle source distribution plans is included in the source distribution result corresponding to the target region, and the particle source distribution plan is used to characterize the implantation trajectory and particle distribution of the radioactive particle;

[0046] In terms of the aspect of displaying the source distribution result corresponding to the at least one target region, the processor is configured to:

[0047] In the target region, display the corresponding at least one set of particle source distribution plans; wherein, different particle source distribution plans have different display attributes;

[0048] In response to a selection operation for any target implantation trajectory or target radioactive particle in the target region, highlight the target particle source distribution plan corresponding to the target implantation trajectory or the target radioactive particle.

[0049] In one embodiment, in terms of highlighting the target implantation trajectory or the target particle source placement plan corresponding to the target radioactive particles, the processor is configured to:

[0050] Highlight the implantation trajectory in the target particle source placement plan; and

[0051] Display the isodose field corresponding to the radioactive particles in the target particle source placement plan; wherein, the isodose field covers the target area; and

[0052] Near the target area, display the trajectory information and particle information of the radioactive particles in the form of a floating window.

[0053] In one embodiment, after displaying the source placement result corresponding to the at least one target area, the processor is further configured to:

[0054] In response to the configured trajectory information and / or particle information not meeting the preset constraint conditions, generate a prompt message; the prompt message is used to prompt the user to change the target source placement mode or modify the configured trajectory information and particle information;

[0055] Near the source placement result, display the prompt message in the form of a pop-up window.

[0056] In a third aspect, the present application further provides a method for placing radioactive particles, which is applied to a radioactive particle placement system, and the method includes:

[0057] Obtain a medical image of the intervention object;

[0058] Extract at least one target area from the medical image;

[0059] In response to a user operation, determine a target mode applied to the at least one target area from a plurality of preset source placement modes; the source placement mode is a method of placing radioactive particles on the intervention object through the user's control operation and / or the program control of the radioactive particle placement system;

[0060] Based on the target mode, perform radioactive particle placement processing on the at least one target area to obtain a source placement result; the radioactive particle placement processing is used to configure the implantation trajectory and spatial distribution of the radioactive particles when implanting them into the intervention object.

[0061] In a fourth aspect, the present application further provides a method for displaying implanted particles, characterized in that the method is applied to an implanted particle display system, and the method includes:

[0062] Display a medical image of the intervention object;

[0063] In response to image recognition and image segmentation operations on the medical image, at least one target region is segmented from the medical image;

[0064] In response to a selection operation for a target source distribution pattern corresponding to the at least one target region, based on the target source distribution pattern, particle source distribution processing is performed on the at least one target region to obtain a source distribution result; the target source distribution pattern is a way to perform particle source distribution on the intervention object through user control operations and / or program control of the particle source distribution system; the particle source distribution processing is used to configure the implantation trajectory and spatial distribution of radioactive particles when implanting into the intervention object;

[0065] In the medical image, the source distribution result corresponding to the at least one target region is displayed.

[0066] In a fifth aspect, the present application further provides a computer device. The computer device includes:

[0067] A processor;

[0068] A memory for storing executable instructions of the processor;

[0069] Wherein, the processor is configured to execute the executable instructions to implement a method for source distribution of implanted particles or a method for displaying implanted particles.

[0070] In a sixth aspect, the present application further provides a computer-readable storage medium, which includes program data. When the program data is executed by a processor of a computer device, the computer device is enabled to execute a method for source distribution of implanted particles or a method for displaying implanted particles.

[0071] In a seventh aspect, the present application further provides a computer program product. The computer program product includes a computer program, and when the computer program is executed by a processor, it implements a method for source distribution of implanted particles or a method for displaying implanted particles.

[0072] The above-mentioned radioactive seed source placement system, radioactive seed display system, related methods, computer devices, storage media, and computer program products, on the one hand, first extract at least one target area from the medical image of the intervention object, and then use the target source placement mode selected by the user to perform radioactive seed source placement processing on the at least one target area, so as to configure the implantation trajectory and spatial distribution of radioactive seeds when implanted into the intervention object, thereby optimizing the process of radioactive seed source placement processing. Compared with the methods in the prior art, the efficiency of radioactive seed source placement is effectively improved with a standardized execution program, and the consumption of manpower and material resources is reduced. On the other hand, through the target source placement mode selected by the user, radioactive seeds are placed in the target area of the intervention object under the control operation of the user and / or the program control of the radioactive seed source placement system to obtain the corresponding radioactive seed source placement result, thereby improving the accuracy and feasibility of radioactive seed source placement and providing more reference information for subsequent medical treatment. Description of the Drawings

[0073] The drawings herein are incorporated into the specification and form a part of this specification, showing embodiments consistent with the present disclosure, and are used together with the specification to explain the principles of the present disclosure, and do not constitute an improper limitation to the present disclosure.

[0074] Figure 1 is a structural diagram of a radioactive seed treatment planning system shown according to an exemplary embodiment.

[0075] Figure 2 is a flowchart of a method executed by a processor of a radioactive seed source placement system shown according to an exemplary embodiment.

[0076] Figure 3 is a module diagram of a method executed by a processor of a radioactive seed source placement system shown according to an exemplary embodiment.

[0077] Figure 4 is a flowchart of configuring trajectory information and seed information of radioactive seeds shown according to an exemplary embodiment.

[0078] Figure 5 is a flowchart of performing radioactive seed source placement processing on an intervention object shown according to an exemplary embodiment.

[0079] Figure 6 is a flowchart of performing radioactive seed source placement processing on an intervention object shown according to an exemplary embodiment.

[0080] Figure 7 is a flowchart of performing radioactive seed source placement processing on an intervention object shown according to an exemplary embodiment.

[0081] Figure 8It is a flowchart of a method executed by a processor of a display system for implanting particles shown according to an exemplary embodiment.

[0082] Figure 9 It is a flowchart of another method executed by a processor of a display system for implanting particles shown according to an exemplary embodiment.

[0083] Figure 10 It is an interface diagram showing a target area of a medical image shown according to an exemplary embodiment.

[0084] Figure 11 It is an interface diagram showing manual adjustment of a particle source placement scheme shown according to an exemplary embodiment.

[0085] Figure 12 It is an interface diagram showing a target particle source placement scheme shown according to an exemplary embodiment.

[0086] Figure 13 It is a block diagram of a source placement device for implanting particles shown according to an exemplary embodiment.

[0087] Figure 14 It is a block diagram of a display device for implanting particles shown according to an exemplary embodiment.

[0088] Figure 15 It is a block diagram of a computer for source placement or display of implanting particles shown according to an exemplary embodiment.

[0089] Figure 16 It is a block diagram of a computer-readable storage medium for source placement or display of implanting particles shown according to an exemplary embodiment.

[0090] Figure 17 It is a block diagram of a computer program product for source placement or display of implanting particles shown according to an exemplary embodiment. Detailed implementation manners

[0091] In order to make the objectives, technical solutions and advantages of the present application clearer, the present application will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application and are not used to limit the present application.

[0092] The term "and / or" in the embodiments of the present application refers to any and all possible combinations including one or more of the associated listed items. It should also be noted that when used in this specification, "including / containing" specifies the presence of the stated features, integers, steps, operations, elements and / or components, but does not exclude the presence or addition of one or more other features, integers, steps, operations, elements and / or components and / or their groups.

[0093] The source distribution system for implanting particles or the display system for implanting particles provided by the embodiments of the present application may be a radioactive particle treatment planning system, that is, a TPS system. This system may be a computer device, and this computer device may be a terminal or a server. Taking the terminal as an example, its internal structure diagram may be as Figure 1 shown. The source distribution system for implanting particles or the display system for implanting particles includes a processor, a memory, a communication interface, a display screen, and an input device connected through a system bus.

[0094] Among them, the processor of the source distribution system for implanting particles or the display system for implanting particles is used to provide computing and control capabilities. The memory of the source distribution system for implanting particles or the display system for implanting particles includes a non-volatile storage medium and an internal memory. The non-volatile storage medium stores an operating system and a computer program. The internal memory provides an environment for the operation of the operating system and the computer program in the non-volatile storage medium.

[0095] Among them, the communication interface of the source distribution system for implanting particles or the display system for implanting particles is used to communicate with an external terminal in a wired or wireless manner. The wireless manner can be implemented through WIFI, a carrier network, NFC (Near Field Communication), or other technologies. When the computer program is executed by the processor, it realizes a method for distributing sources of implanting particles or a method for displaying implanting particles.

[0096] Among them, the display screen of the source distribution system for implanting particles or the display system for implanting particles may be a liquid crystal display screen or an electronic ink display screen. The input device of the source distribution system for implanting particles or the display system for implanting particles may be a touch layer covering the display screen, or may be a button, a trackball, or a touchpad provided on the shell of the source distribution system for implanting particles or the display system for implanting particles, or may also be an external keyboard, touchpad, or mouse, etc.

[0097] Those skilled in the art can understand that Figure 1 the structure shown in

[0098] is only a block diagram of some structures related to the solution of the present application, and does not constitute a limitation on the source distribution system for implanting particles or the display system for implanting particles to which the solution of the present application is applied. The specific source distribution system for implanting particles or the display system for implanting particles may include more or fewer components than those shown in the figure, or combine some components, or have different component arrangements.

[0099] When this system is applied to Figure 1Taking the processor in [as an example for illustration, such as Figure 2 and Figure 3 as shown, Figure 2 FIG. Figure 2 is a schematic flowchart of a computer program executed by a processor of a source distribution system for implanting particles shown according to an exemplary embodiment. Figure 3 FIG. Figure 3 is a module diagram of a computer program executed by a processor of a source distribution system for implanting particles shown according to an exemplary embodiment. When the above-mentioned processor executes the computer program, it specifically is used to execute the following steps:

[0100] Step S11: Obtain a medical image of the intervention object.

[0101] Wherein, the intervention object is a medical diagnosis and treatment object to be subjected to medical intervention treatment.

[0102] In some embodiments, the medical diagnosis and treatment object may be a human object or an animal object, etc.

[0103] In one embodiment, the medical image includes an internal tissue image of the intervention object collected by a preset imaging method.

[0104] Wherein, the imaging method may include, for example, Magnetic Resonance (MR) imaging method, Computed Tomography Angiography (CTA) method, Digital Subtraction Angiography (DSA) method, Computed Tomography Perfusion (CTP) method, Computed Tomography (CT) method, etc. for providing high-resolution, three-dimensional reconstructed tissue images. Therefore, the obtained medical images may include, for example, MR images, CTA images, DSA images, CTP images, CT images, etc., so that the processor can obtain and display various types and medical images at each diagnosis and treatment stage expected by the user according to the user's selection operation, so as to improve the efficiency and generalization ability of particle source distribution processing.

[0105] As an example, an intervention object is a human patient object. The processor responds to the user's image upload operation, loads the CT image of the patient object selected by the user into the source distribution system, and thus displays the CT image in a three-dimensional image manner on the particle source distribution interface. Among them, the loaded CT image includes the first diagnosis image of the patient object (that is, the CT image taken when the patient object is first subjected to medical diagnosis and treatment) and the preoperative image (that is, the CT image taken when the patient object is currently subjected to medical diagnosis and treatment).

[0106] Step S12: Extract at least one target region from the medical image.

[0107] Specifically, the processor displays the medical image in the particle source distribution interface in the form of a two-dimensional image or a three-dimensional image for the user to perform image analysis on the medical image, so as to complete operations such as image browsing, image recognition, image segmentation, and region annotation of the medical image, extract at least one segmented image region as the target region, and fuse and display the extracted target region in the particle source distribution interface for the user to view and edit.

[0108] In some embodiments, the original medical image corresponding to the intervention object is a cross-sectional image. The processor first displays the cross-sectional image in the particle source distribution interface for the user to perform three-dimensional reconstruction processing on it to obtain the corresponding reconstructed three-dimensional medical image; then, in the particle source distribution interface, based on the reconstructed three-dimensional medical image, construct and display the corresponding sagittal plane image, coronal plane image, etc., so as to display the relevant tissue regions of the intervention object in all directions, facilitating subsequent users to perform image analysis and image processing on the displayed images, thereby improving the efficiency of particle source distribution processing and reducing the complexity of user operations.

[0109] Among them, the operations of image recognition, image segmentation, and region annotation on the medical image can be manual operations of the user or automatic operations of the processor, so that the user can flexibly select the corresponding manual operation or automatic operation according to the actual needs of image processing, thereby improving the efficiency of particle source distribution processing and the flexibility of image processing.

[0110] In some embodiments, the image recognition operation is used to identify the types of tissue regions in the medical image. For example, identify lesion regions of types such as tumors in the medical image, and identify dangerous regions of types such as blood vessels and vital organs in the medical image.

[0111] In some embodiments, the image segmentation operation is used to segment relevant tissue regions in the medical image, including image regions of lesion tissue regions in the lungs, liver, etc. Among them, the image segmentation operation of the tissue region can be automatically segmented under the drive of the automatic program of the processor or manually segmented under the manual planning of the user.

[0112] In some embodiments, the region annotation operation is used to annotate reference information about particle source distribution such as the region area, spatial position, and tissue region type corresponding to the segmented image region.

[0113] In one embodiment, the target region is a first type of tissue region in the intervention object that is marked and spans multiple object cross-sections, and in the medical image of the intervention object, there is also a second type of tissue region that is marked and spans multiple object cross-sections.

[0114] In some embodiments, the medical image obtained by the processor is a three-dimensional stereoscopic image reconstructed from multiple two-dimensional cross-sectional images of the internal tissue structure of the intervention object, and the plane layer where the two-dimensional cross-sectional image is located in the medical image is the object cross-section. Among them, the plane layer is the tissue plane layer for the intervention object.

[0115] As an example, the processor first obtains multiple two-dimensional cross-sectional images of the internal tissue structure of the intervention object, and then reconstructs the corresponding three-dimensional stereoscopic image based on the image information in each cross-sectional image. Among them, the image information may include, for example, the intercept size, pixel size, pixel distance, and pixel dimension of the image.

[0116] In certain embodiments, the thickness of the tissue plane layer represented by the two-dimensional cross-sectional image may be 1 mm, 2 mm, etc., and no specific limitation is made here.

[0117] In certain embodiments, the two-dimensional cross-sectional image may specifically be a cross-sectional image, a coronal plane image, or a sagittal plane image of the intervention object, etc., and no specific limitation is made here.

[0118] In some embodiments, the first type of tissue region may be a solid lesion region (such as a tumor or other lesion region) in the intervention object that spans multiple object cross-sections, and the second type of tissue region may be a solid risk region (such as important organ regions such as blood vessels and bones) in the intervention object that spans multiple object cross-sections.

[0119] Step S13: In response to a user operation, determine a target mode applied to at least one target region from a variety of preset source distribution modes.

[0120] Specifically, in the particle source distribution interface of the source distribution system, there are multiple source distribution modes for each target region for the user to select. Therefore, the processor can determine the source distribution mode corresponding to each target region based on the user's selection operation. Among them, the source distribution mode is a way to perform particle source distribution on the intervention object through the user's control operation and / or the program control of the particle source distribution system.

[0121] In one embodiment, the source distribution mode includes: a first mode of automatically performing particle source distribution on the intervention object under the program control of the particle source distribution system. It can be understood that the first mode is an automatic source distribution mode that uses the program control of the particle source distribution system to perform particle source distribution.

[0122] In another embodiment, the source distribution mode includes: a second mode of manually performing particle source distribution on the intervention object under the user's control operation. It can be understood that the second mode is a manual source distribution mode that uses the user's control operation to perform particle source distribution.

[0123] In another embodiment, the radioactive seed source mode includes a third mode in which, under the control operation of the user and the program control of the radioactive seed source system, radioactive seeds are semi-automatically implanted into the intervention object. It can be understood that the third mode is a semi-automatic radioactive seed source mode that utilizes the control operation of the user and the program control of the radioactive seed source system to implant radioactive seeds.

[0124] Among them, by allowing the user to independently select the corresponding target radioactive seed source mode, it is convenient for the user to flexibly select the corresponding radioactive seed source mode according to the actual needs of radioactive seed source treatment, thereby improving the efficiency and flexibility of radioactive seed source treatment.

[0125] Step S14: Based on the target mode, perform radioactive seed source treatment on at least one target region to obtain a radioactive seed source result.

[0126] In one embodiment, the radioactive seed source treatment is used to configure the implantation trajectory and spatial distribution of radioactive seeds when implanted into the intervention object.

[0127] Among them, the trajectory information of the radioactive seeds includes at least the trajectory length and trajectory direction of the implantation trajectory; the seed information includes at least the seed position, the number of seeds, and the seed activity when the radioactive seeds are implanted into the intervention object.

[0128] In some embodiments, the implantation trajectory of the radioactive seeds when implanted into the intervention object refers to the implantation path of the radioactive seeds when implanted into the intervention object. This implantation path is related to information such as the path length and path direction of the radioactive seeds in the intervention object. Therefore, the implantation trajectory of the radioactive seeds when implanted into the intervention object can be characterized based on the corresponding trajectory information. That is, the radioactive seed source treatment needs to perform path planning on the implantation trajectory of the radioactive seeds. Thus, the user can intuitively understand information such as the path length and path direction of the radioactive seeds in the intervention object based on the corresponding trajectory information in the radioactive seed source result, so as to facilitate the user to judge the effect of the radioactive seed source treatment, thereby improving the diagnosis and treatment effect of performing related intervention treatments on the intervention object.

[0129] In some embodiments, the spatial distribution of the radioactive seeds refers to the distribution of the radioactive seeds in the internal space of the intervention object. This distribution is related to information such as the type, position, number, and distribution form of the radioactive seeds. Therefore, the spatial distribution of the radioactive seeds when implanted into the intervention object can be characterized based on the corresponding seed information. That is, the radioactive seed source treatment needs to perform seed planning on the seed information of the radioactive seeds. Thus, the user can intuitively understand information such as the type, position, number, and distribution form of the radioactive seeds based on the corresponding seed information in the radioactive seed source result, so as to facilitate the user to judge the effect of the radioactive seed source treatment, thereby improving the diagnosis and treatment effect of performing related intervention treatments on the intervention object.

[0130] Among them, the distribution form of the radioactive particles can be in the form of dots, lines or planes.

[0131] Specifically, step S14 may be: under the target mode selected by the user, the processor configures the trajectory information and particle information of the radioactive particles when implanting into the target area of the intervention object based on the preset source distribution rule in response to the user's control operation and / or the program control of the particle source system.

[0132] In an exemplary embodiment, refer to Figure 4 , Figure 4 is a schematic flowchart of an embodiment for configuring the trajectory information and particle information of the implanted particles in the present application. In step S14, that is, in the aspect where the processor configures the trajectory information and particle information of the radioactive particles when implanting into the target area of the intervention object based on the preset source distribution rule, the technical content of the following method may be specifically executed:

[0133] Step S141: Based on the target points in the target area, obtain multiple candidate implantation trajectories for the target area.

[0134] Among them, the target point is a voxel point with specific biological functions or biochemical characteristics in the target area, which can be used for medical treatment or diagnosis. Specifically, it is used as the trajectory end point of the implantation trajectory to be configured in the body of the intervention object.

[0135] In some embodiments, the spatial positions of the target points in the target area are distributed within a specific area range in the target area. Among them, the specific area is a spherical area constructed with the corresponding area centroid point or area center point as the center of the sphere in the target area.

[0136] In some embodiments, the specific spatial size range occupied by the specific area in the target area can be specifically defined according to actual needs. For example, the spatial size range can be obtained by taking the area centroid point or area center point as the center of the sphere and expanding outward by a preset number of voxel point diameters (such as 5 voxel point diameters, 10 voxel point diameters, etc.); another example is that the spatial size range can also be obtained by taking the area centroid point or area center point as the center of the sphere and expanding outward by a preset radius length (such as 0.1 mm, 0.5 mm, etc.).

[0137] As an example, based on the extracted target area, the processor first determines the target voxel point corresponding to the position of the centroid point in the target area; then takes this target voxel point as the center of the sphere to obtain a spherical area with a preset diameter length, and uses this spherical area as the target point area in the target area; then, takes at least some of the voxel points in the target point area as the target points in the target area; finally, takes the target points as the emission points and emits multiple trajectories to the body surface of the intervention object to obtain the corresponding multiple candidate implantation trajectories.

[0138] In some embodiments, each target point distributed within the specific region occupies at least one voxel position in the target region. The number of target points can be one or multiple, and the number of candidate implantation trajectories emitted by each target point can be one or multiple, which is not specifically limited here. Thus, the user can independently select the target points at the corresponding voxel positions, the number of target points, and the number of candidate implantation trajectories according to the actual requirements of the particle source distribution, so as to perform the particle source distribution, thereby improving the efficiency and flexibility of the particle source distribution process.

[0139] Step S142: Under the limitation of a preset first constraint condition, based on the volume, spatial position of the target region, and the target skin distances of each candidate implantation trajectory, at least one target implantation trajectory is selected from multiple candidate trajectories to obtain the corresponding trajectory information.

[0140] Specifically, the processor first calculates the volume size and spatial position of the target region in a preset coordinate system, as well as the target skin distances of each candidate implantation trajectory based on the extracted target region; then, according to the volume size and spatial position of the target region and the target skin distances of the candidate implantation trajectories, it determines whether each candidate implantation trajectory meets the preset constraint conditions, and selects at least one target implantation trajectory that meets the constraint conditions from each candidate implantation trajectory to obtain the trajectory information of the corresponding radioactive particles.

[0141] Among them, the trajectory information of the radioactive particles includes at least the trajectory length and trajectory direction of the target implantation trajectory.

[0142] Among them, the preset coordinate system can be a two-dimensional coordinate system composed of a two-dimensional plane where the target region is located, a three-dimensional coordinate system with the image center of the medical image as the origin, a three-dimensional coordinate system with the region center of the target region as the origin, or a three-dimensional coordinate system with the object center of the intervention object as the origin, etc., which is not specifically limited here.

[0143] In some embodiments, during the process of planning the candidate implantation trajectories, the processor first starts from a target point located inside the target region and extends it towards the outer contour of the target region, and forms a first intersection point on the outer contour of the target region to obtain a first segment of the trajectory with the target point and the first intersection point as endpoints; then, it continues to extend from the first intersection point towards the outer contour of the intervention object and forms a second intersection point on the outer contour of the intervention object to obtain a second segment of the trajectory with the first intersection point and the second intersection point as endpoints; finally, the first segment of the trajectory and the second segment of the trajectory are spliced to obtain the candidate implantation trajectory.

[0144] Among them, the first intersection point on the outer contour of the target area can also be understood as the trajectory entry point of the candidate implant trajectory for the target area, and the second intersection point on the outer contour of the intervention object can also be understood as the trajectory entry point of the candidate implant trajectory for the intervention object.

[0145] In one embodiment, the processor may also use the distance between the target point in the target area and the second intersection point on the outer contour of the intervention object as the target-skin distance of the candidate implantation trajectory, that is, use the length of the entire candidate implantation trajectory as the target-skin distance.

[0146] In another embodiment, the processor may use the distance between the first intersection point on the outer contour of the target area and the second intersection point on the outer contour of the intervention object as the target skin distance of the candidate implant trajectory, that is, the length of the corresponding spliced ​​second segment of the candidate implant trajectory as the target skin distance.

[0147] In other embodiments, the processor may also use the distance between the target point in the target area and the first intersection point on the outer contour of the target area as the target-skin distance of the candidate implantation trajectory, that is, use the length of the first corresponding spliced ​​trajectory in the candidate implantation trajectory as the target-skin distance.

[0148] Among them, the specific method for determining the target-skin distance of the candidate implantation trajectory can be determined according to actual needs. For example, different methods for determining the target-skin distance are applicable to different interventional treatment methods and radioactive particles to be implanted, and no specific limitation is made here.

[0149] In some embodiments, taking into account factors such as the radiation effect of particles on the target area and the subsequent interventional treatment costs, during the planning of particle source distribution, the number of screened target implantation trajectories can be one or more, so that the radiation area of ​​the particles in the target implantation trajectory can cover the entire lesion as much as possible, thereby improving the effect and flexibility of particle source distribution treatment.

[0150] For example, in some embodiments, the processor can pre-set multiple volume ranges and the number of target implantation trajectories required for each volume range, so that when screening target implantation trajectories for the target area, the required number of target implantation trajectories can be screened out from the candidate implantation trajectories according to the volume range corresponding to the target area, so that when the volume of the current lesion area is large, a larger number of implantation trajectories can be set for it; and when the volume of the current lesion area is small, a smaller number of implantation trajectories can be set for it.

[0151] In one embodiment, the process of screening the target implantation trajectory from the candidate implantation trajectories can be regarded as a process of traversing the target points in the target area, that is, while traversing each candidate target point in the target area, screening the candidate implantation trajectories corresponding to the candidate target points until the target implantation trajectory that meets the planning requirements is screened out, and then stopping the traversal operation of the candidate target points.

[0152] Specifically, the processor first takes each voxel point in the target area located within the target point area as a candidate target point; then traverses each candidate target point in sequence until the target implantation trajectory that meets the planning requirements is screened out, and then stops the traversal operation of the candidate target points.

[0153] In one embodiment, in terms of screening at least one target implantation trajectory that meets the constraint conditions, the processor is configured to: screen at least one target implantation trajectory from the candidate implantation trajectories under the limitation of the first constraint condition.

[0154] Wherein, the first constraint condition at least includes a first sub-constraint condition, a second sub-constraint condition, and a third sub-constraint condition.

[0155] In some embodiments, the first sub-constraint condition is used to limit the cross-layer angle of the target implantation trajectory when crossing the object cross-sections of different plane layers to be less than or equal to a preset angle.

[0156] Specifically, since radioactive particles need to cross multiple layers of object cross-sections when implanted into the intervention object, and different layers of object cross-sections correspond to different tissue regions. Therefore, in order to ensure the safety of the interventional treatment, when screening the target implantation trajectory, it is necessary to ensure that its cross-layer angle is within the preset angle range, that is, to limit the cross-layer angle of the target implantation trajectory when crossing the object cross-sections of different layers to be less than or equal to the preset angle, such as 10 degrees.

[0157] In some embodiments, the second sub-constraint condition is used to limit the trajectory length of the target implantation trajectory to be less than or equal to a preset length.

[0158] Specifically, in order to ensure the safety of the interventional treatment, when screening the target implantation trajectory, it is necessary to limit the safe target skin distance range, that is, to limit the length between the needle entry point of the target implantation trajectory on the outer contour of the intervention object and the needle entry point of the corresponding target area outer contour to be less than or equal to the preset length, such as the target skin distance cannot exceed 20 cm.

[0159] In some embodiments, the third sub-constraint condition is used to limit the distance between the target implantation trajectory and the second type of tissue area to be greater than or equal to a preset distance.

[0160] Specifically, to ensure the safety of interventional therapy, when screening for the target implantation trajectory, it is necessary to limit the distance between the implantation trajectory and the dangerous tissue area to be within the safe distance range, that is, to limit the distance between the planned implantation trajectory and the second type of tissue area of the intervention object to be greater than or equal to the preset distance, so that when performing particle implantation, radioactive particles can avoid dangerous tissues such as blood vessels and bones.

[0161] Among them, the target implantation trajectory is screened through a preset first constraint condition, which meets the actual requirements during particle source distribution, thereby improving the accuracy and safety during particle source distribution processing.

[0162] Step S143: Under the limitation of a preset second constraint condition, configure corresponding particle information based on volume, position, and trajectory information.

[0163] In one embodiment, the particle information at least includes the particle position, particle quantity, and particle activity when the radioactive particle is implanted into the intervention object.

[0164] Specifically, the processor first obtains the volume size, spatial position, and corresponding planned trajectory information of the target area in a preset coordinate system; then, under the limitation of a preset second constraint condition, according to the volume size, spatial position, and corresponding planned trajectory information of the target area, plan the particle position, particle quantity, and particle activity when the radioactive particle is implanted into the intervention object to obtain the particle information of the corresponding radioactive particle.

[0165] In some embodiments, the volume size of the target area is positively correlated with the particle quantity in the corresponding configured particle information, that is, if the volume of the target area is larger, the particle quantity of the radioactive particles to be implanted into the intervention object is more; if the volume of the target area is smaller, the particle quantity of the radioactive particles to be implanted into the intervention object is less. Among them, by setting the relationship between the volume of the target area and the particle quantity of the radioactive particles in this way, the radiation area of the radioactive particles in the target implantation trajectory can cover the entire lesion area as much as possible, so as to improve the effect and flexibility of particle source distribution processing.

[0166] In some embodiments, the particle information of the radioactive particles to be implanted into the intervention object may further include the particle type.

[0167] Among them, the particle type of the radioactive particle may include, for example, radioactive iodine, radioactive cesium, radioactive cobalt, etc., and radioactive particles of different particle types have different energies and penetration capabilities. Therefore, the processor can also select the corresponding appropriate particle type based on the actual requirements in the subsequent radioactive diagnosis and treatment process of the intervention object, such as the condition of the patient object and the corresponding medical diagnosis and treatment methods.

[0168] In some embodiments, after configuring the particle information of the radioactive seeds, the processor can also determine the isodose field of the radioactive seeds based on the configured particle positions.

[0169] The isodose field is used to characterize the radiation range of the radioactive seeds on the target area.

[0170] In some embodiments, the isodose field of the radioactive seeds can be used to describe the radiation transmission of radioactive substances within the intervention object and to evaluate the impact of the radiation on the intervention object. Specifically, the isodose field of the radioactive seeds refers to the situation where the dose generated by the radioactive seeds is spatially uniform within a certain area.

[0171] In one embodiment, in terms of configuring the corresponding particle information, the processor is configured to: under the limitation of the second constraint condition, configure the particle positions, particle numbers, and particle activities of the radioactive seeds in at least one implantation trajectory.

[0172] The second constraint condition includes a fourth sub-constraint condition, a fifth sub-constraint condition, and a sixth sub-constraint condition.

[0173] In some embodiments, the fourth sub-constraint condition is used to limit the distance between the radiation range corresponding to the radioactive seeds and the second type of tissue region to be greater than or equal to a preset distance.

[0174] Specifically, to ensure the safety of the interventional treatment, when planning the particle positions, it is necessary to limit the distance between the radiation range corresponding to the radioactive seeds and the second type of tissue region to be greater than or equal to a preset distance, so that the isodose field when the seeds are implanted into the intervention object cannot irradiate the dangerous tissue region. For example, the distance between the radiation range of the seeds and the dangerous tissue is restricted to not be less than 5 mm.

[0175] In some embodiments, the fifth sub-constraint condition is used to limit the distance between two adjacent radioactive seeds to be greater than or equal to a preset distance.

[0176] Specifically, to ensure the safety of the interventional treatment, when planning the particle positions, it is necessary to limit the distance between two adjacent radioactive seeds in the same implantation trajectory (i.e., the needle track) to be greater than or equal to a preset distance, so that the radiation energies of the two seeds when implanted into the intervention object do not overlap and enhance. For example, the distance between the seeds on the same needle track is restricted to not be less than 0.5 cm.

[0177] In some embodiments, the sixth sub-constraint condition is used to limit the particle activity to be less than or equal to a preset activity.

[0178] Specifically, to ensure the safety of interventional therapy, when planning the particle activity, it is necessary to limit the particle activity to be less than or equal to a preset activity, so that the radiation energy of the particles when implanted into the intervention object is within a safe range. For example, the effective range for limiting the particle activity is within (0.01 - 10.00 mCi).

[0179] Among them, mCi is a unit of ionizing radiation, and its Chinese name is "millicurie". Among them, mCi is used to measure the activity of radioactive particles, that is, the number of nuclear decays per unit time.

[0180] In other embodiments, the processor can also configure a corresponding appropriate particle type as the particle information of the planned radioactive particles according to the actual needs in the subsequent radioactive diagnosis and treatment process to be performed on the intervention object. For example, configure the particle type of the radioactive particles according to the condition of the patient object and the medical diagnosis and treatment method to be performed.

[0181] Among them, the particle information of the radioactive particles is planned through a preset second constraint condition, thus meeting the actual needs during particle source distribution, and improving the accuracy and safety during particle source distribution processing.

[0182] For the above-mentioned particle source distribution system for implanting particles, on the one hand, first extract at least one target area from the medical image of the intervention object, and then use the target source distribution mode selected by the user to perform particle source distribution processing on the at least one target area to configure the implantation trajectory and spatial distribution of the radioactive particles when implanted into the intervention object, thus optimizing the process of particle source distribution for implanting particles, and compared with the methods in the prior art, effectively improving the efficiency of particle source distribution with a standardized execution procedure and reducing the consumption of manpower and material resources; on the other hand, through the target source distribution mode selected by the user, under the control operation of the user and / or the program control of the particle source distribution system, perform particle source distribution on the target area of the intervention object to obtain the corresponding particle source distribution result, thus improving the accuracy and feasibility of particle source distribution for implanting particles and providing more reference information for subsequent medical treatment.

[0183] Those skilled in the art can understand that in the above system of the specific implementation manner, the disclosed system functions can be realized in a more specific manner. For example, the above-described embodiment in which the processor responds to the user operation and determines the target mode applied to at least one target area from a variety of preset source distribution modes is merely illustrative.

[0184] In an exemplary embodiment, refer to Figure 5 , Figure 5This is a schematic flowchart of an embodiment for performing particle source distribution processing on an intervention object in this application. In step S14, that is, in terms of the processor performing particle source distribution processing on at least one target area based on a target mode, the technical content of the following method can be specifically executed:

[0185] Step 1: When the target mode is the first mode, in response to the program control of the particle source distribution system, based on the preset source distribution rules, configure multiple groups of trajectory information and corresponding and matching multiple groups of particle information for at least one target area.

[0186] Specifically, for each target area, when the user selects the first mode for the particle source distribution system to automatically perform particle source distribution, the processor responds to the program control of the particle source distribution system. First, it automatically calculates the volume size, spatial position, and target skin distance of the target area in the object coordinate system; then, it initializes and sets particle information such as the type, activity, and quantity of radioactive particles; then, based on the particle information, preset constraint conditions, and the volume size, spatial position, and target skin distance of the target area, it plans multiple groups of particle source distribution schemes. Among them, each group of particle source distribution schemes includes the trajectory information of the planned implantation trajectory and the corresponding and matching particle information of the radioactive particles.

[0187] Among them, the isodose field corresponding to each group of particle source distribution schemes can achieve full coverage of the target area. That is, each group of trajectory information includes no less than one planned implantation trajectory, and when the isodose fields corresponding to the particle information configured in each implantation trajectory are combined, the coverage area of the total isodose field can uniformly and comprehensively cover the entire lesion area.

[0188] Step 2: Based on the multiple groups of trajectory information and the corresponding and matching multiple groups of particle information, determine the target trajectory information and the corresponding and matching target particle information.

[0189] Specifically, after the particle source distribution system automatically configures all groups of particle source distribution schemes, the processor displays each group of particle source distribution schemes on the system interface; then, the user or the particle source distribution system selects a corresponding group of target particle source distribution schemes in this system interface based on the preset screening rules as the planned scheme to be executed, and uses the trajectory information and particle information in this planned scheme as the target trajectory information and the corresponding and matching target particle information.

[0190] Among them, when the user does not select a target particle source distribution scheme, the processor displays all groups of particle source distribution schemes on the system interface and uses different colors to distinguish different groups of particle source distribution schemes.

[0191] Wherein, when the user selects the implantation trajectories of a certain group of target particle source distribution schemes, the processor highlights all the implantation trajectories and the isodose fields of the radioactive particles corresponding to the group of target particle source distribution schemes on the system interface for the user to view.

[0192] Wherein, by displaying and highlighting the particle source distribution schemes in different colors as described above, it is convenient for the user to clearly distinguish and analyze various different particle source distribution schemes, thereby improving the accuracy and safety during subsequent interventional treatment of the intervention object.

[0193] Further, after the user views the group of particle source distribution schemes, if the processor responds that the group of schemes meets the user's requirements, the group of particle source distribution schemes is used as the planning scheme to be executed to complete the scheme planning; if the processor responds that the group of schemes does not meet the user's requirements, the trajectory information and particle information in the group of particle source distribution schemes are adjusted based on the user's control operation to complete the scheme planning; or, based on the user's control operation, the particle source distribution mode is switched to the corresponding manual mode or semi-automatic mode to reconfigure the particle source distribution scheme for the target area and highlight it for the user to confirm; or, based on the user's selection operation, a new group of target particle source distribution schemes is selected from multiple groups of particle source distribution schemes to highlight the new target particle source distribution scheme for the user to confirm.

[0194] In an embodiment, when displaying each group of particle source distribution schemes, the processor generates prompt information for each group of particle source distribution schemes in combination with the three-dimensional coordinates of dangerous tissue areas such as blood vessels / heart identified during image recognition. The prompt information is used to prompt the user of possible dangerous items in the scheme. For example, if the distance between a certain implantation trajectory and a dangerous tissue is relatively close, the prompt information is used to prompt the user which trajectory in the current scheme is at risk and to prompt the user to select other planning schemes or manually adjust the current scheme.

[0195] Wherein, by performing dangerous prompts and re-planning on the particle source distribution schemes as described above, it is convenient for the user to timely and accurately adjust the particle source distribution schemes, thereby improving the accuracy and safety during subsequent interventional treatment of the intervention object.

[0196] In an exemplary embodiment, refer to Figure 6 , Figure 6 This is a schematic flowchart of an embodiment of particle source distribution processing for an intervention object in the present application. In step S14, that is, in terms of the processor performing particle source distribution processing on at least one target area based on a target mode, the technical content of the following method can be specifically executed:

[0197] Step 1: When the target mode is the second mode, in response to the user's control operation, configure the trajectory information for at least one target area.

[0198] Specifically, for each target area, when the user selects the second mode for manual particle source placement by the user, the processor first calculates and displays the volume size, spatial position, and target skin distance of the target area in the object coordinate system; then, in response to the user's control operation, plan the trajectory length and trajectory direction of the implantation trajectory in the target area to obtain the trajectory information.

[0199] Among them, the trajectory information includes the same-layer implantation trajectory planned by the user on the two-dimensional plane and the cross-layer implantation trajectory planned in the three-dimensional space.

[0200] Step 2: In response to the program control of the particle source placement system, based on the preset source placement rules and trajectory information, configure the particle information for the at least one target area.

[0201] In one embodiment, if the number of implantation trajectories planned by the user is only one, the processor automatically plans the particle information for the implantation trajectory based on the implantation trajectory, the preset constraint conditions, and the volume size, spatial position, and target skin distance of the target area to obtain a complete particle source placement plan.

[0202] In another embodiment, if the number of implantation trajectories planned by the user is multiple, the processor plans the particle information for each implantation trajectory based on all the implantation trajectories, the influence relationship between the particle information corresponding to each implantation trajectory, the preset constraint conditions, and the volume size, spatial position, and target skin distance of the target area to obtain a complete particle source placement plan.

[0203] Among them, after obtaining the complete particle source placement plan, the processor displays all the implantation trajectories and the isodose field of the radioactive particles corresponding to the particle source placement plan in real time on the two-dimensional / three-dimensional system interface for the user to view, so that the user can adjust the particle source placement plan in a timely and accurate manner, thereby improving the accuracy and safety of subsequent interventional treatment of the intervention object.

[0204] Further, after the user views the particle source distribution scheme, if the processor responds that the scheme meets the user's requirements, the particle source distribution scheme is used as the planning scheme to be executed to complete the scheme planning; if the processor responds that the scheme does not meet the user's requirements, the user can select to adjust the implantation trajectory / particle quantity / particle attributes in the particle source distribution scheme in the system interface in the way of automatic planning / semi-automatic planning / manual planning, so as to obtain a new implantation trajectory and / or particle information, and re-plan the trajectory information of each implantation trajectory and the particle information of the corresponding radioactive particles in the particle source distribution scheme according to the new implantation trajectory and / or particle information, so as to obtain a new particle source distribution scheme.

[0205] In one embodiment, when displaying the particle source distribution scheme planned by the user, the processor generates prompt information for the particle source distribution scheme by combining the three-dimensional coordinates of dangerous tissue regions such as blood vessels / heart identified in the image recognition process. The prompt information is used to prompt the user of possible dangerous items in the scheme. For example, if the distance between a certain implantation trajectory and a dangerous tissue is relatively close, the prompt information is used to prompt the user which trajectory in the current scheme has risks, and prompt the user to select other planning schemes or manually adjust the current scheme.

[0206] In an exemplary embodiment, refer to Figure 7 , Figure 7 is a schematic flowchart of an embodiment of particle source distribution processing for an intervention object in this application. In step S14, that is, in terms of the processor performing particle source distribution processing on at least one target area based on a target mode, the technical content of the following manner can be specifically executed:

[0207] Step 1: When the target mode is the third mode, based on the user's annotation operation for at least one target area, at least one annotation area is divided in the target area, and corresponding annotation content is marked in the at least one annotation area.

[0208] Specifically, for each target area, when the user selects the third mode for the semi-automatic particle source distribution of the source distribution system, the processor first calculates and displays the volume size, spatial position, and target skin distance of the target area in a preset coordinate system; then, initializes and displays information such as the type, activity, quantity, etc. of radioactive particles; finally, responds to the user's area annotation operation for each target area respectively to determine at least one annotation area in each target area and the annotation content corresponding to the at least one annotation area.

[0209] Among them, the user's area annotation operation is used to perform area division and area annotation on the target area in sequence, that is, the user first divides at least one annotation area in the displayed target area, and then edits annotation information for the at least one annotation area.

[0210] In one embodiment, in a two-dimensional / three-dimensional system interface, after the user freely divides the target area into marked areas, the source distribution system can set the depth of the background color of the area according to the volume of each marked area, or the user can also customize the background color of each marked area. For example, the user can adjust the color transparency within each marked area through the display panel on the system interface.

[0211] In one embodiment, after the user freely divides the target area into multiple marked areas, the user can customize and edit the marked content for each marked area. The marked content can be used to indicate the source distribution mode, planning requirements, etc. for the marked area. For example, for some marked areas, the user can mark the content with a heavier particle dose, and then when planning the particle source distribution scheme for it later, a larger degree of distribution of the number and activity of particles can be made; another example is that for some marked areas, the user can mark the content indicating that the area is a dangerous tissue area, and then when planning the particle source distribution scheme for it later, a more cautious distribution of the direction, position of the implantation trajectory, and the number and activity of particles can be selected in a manual planning manner to avoid the isodose field of the particles covering the dangerous tissue area; another example is that for some marked areas, the user can mark the automatic planning mode / semi-automatic planning mode / manual planning mode, and then when planning the particle source distribution scheme for it later, the trajectory information and particle information can be configured based on the automatic planning of the system program and / or the manual planning of the user.

[0212] Step 2: For the unmarked areas in the target area, in response to the program control of the particle source distribution system, based on the preset source distribution rules, configure the trajectory information and particle information for the unmarked areas; and for at least one marked area, in response to the user's control operation and / or the program control of the particle source distribution system, configure the trajectory information and particle information for the marked area based on the marked content.

[0213] Specifically, after the user completes the area marking of the target area, the processor, for the unmarked areas in the target area, by default in an automatic source distribution mode, automatically configures the trajectory information and particle information for the unmarked areas to obtain a particle source distribution scheme for the unmarked areas. And for the marked areas in the target area, the processor responds to the source distribution mode independently selected by the user for different marked areas, and configures the trajectory information and particle information for the marked areas in an automatic planning / semi-automatic planning / manual planning manner to obtain a particle source distribution scheme for the marked areas.

[0214] In some embodiments, when planning and configuring the particle source distribution scheme for the unlabeled area and the labeled area, the processor may first plan the trajectory information and particle information of the labeled area, so that after the planning of all the labeled areas is completed, the trajectory information and particle information of the unlabeled area are planned.

[0215] In some embodiments, for multiple areas (including unlabeled areas and labeled areas) where the processor plans the particle source distribution scheme in the automatic planning mode, it may perform the planning and configuration for each of them in the corresponding order based on the volume sizes between the areas.

[0216] As an example, for multiple labeled areas marked by the user, there are a total of 5 target labeled areas where the particle source distribution scheme is planned in the automatic planning mode. The processor may perform the planning and configuration of the particle source distribution scheme for them in the corresponding order according to the volume sizes between the 5 target labeled areas.

[0217] In some embodiments, for multiple labeled areas marked by the user, the processor may perform the planning and configuration for each of them in the corresponding order based on the corresponding planning requirements. Among them, the planning requirements include the labeled content with a heavier particle dose, the labeled content of the dangerous tissue area, etc.

[0218] As an example, for multiple labeled areas marked by the user, the processor may first perform the planning and configuration of the particle source distribution scheme for the labeled area with the labeled content of "heavier particle dose"; then, perform the planning and configuration of the particle source distribution scheme for the labeled area with the labeled content of "dangerous tissue area"; finally, perform the planning and configuration of the particle source distribution scheme for the remaining labeled areas in the corresponding order according to the volume sizes between them.

[0219] Among them, through the above-mentioned labeling operation of the user on the target area and according to the corresponding labeled area and labeled content to perform the particle source distribution scheme, the planned particle source distribution scheme can meet the actual needs of the user and improve the accuracy of the particle source distribution.

[0220] In some embodiments, after performing the configuration planning of the trajectory information and particle information for both the unlabeled area and the labeled area and obtaining the corresponding particle source distribution scheme, in the display interface of the particle source distribution system, the particle source distribution schemes of the unlabeled area and the labeled area may be displayed in the corresponding order of their respective planning, or they may be displayed synchronously, which is not specifically limited here.

[0221] Further, after performing configuration planning on both the unlabeled area and the labeled area regarding trajectory information and particle information and obtaining the corresponding particle source distribution plan, if the processor responds that the particle source distribution plan meets the user's requirements, then this particle source distribution plan is taken as the planning plan to be executed to complete the plan planning; if the processor responds that the particle source distribution plan does not meet the user's requirements, the user can re-select in the system interface to re-plan the unlabeled area or the labeled area in the way of automatic planning / semi-automatic planning / manual planning to obtain a new particle source distribution plan; or, the user can also re-divide the unlabeled area or the labeled area in the system interface to obtain a new unlabeled area and a new labeled area, and then re-perform configuration planning on the new unlabeled area in the way of automatic planning to obtain the corresponding new particle source distribution plan, and select in the system interface to perform configuration planning on the new labeled area in the way of automatic planning / semi-automatic planning / manual planning to obtain a new particle source distribution plan.

[0222] In one embodiment, when the particle source distribution plan for the labeled area or the unlabeled area in the target area is planned, the source distribution system immediately displays the corresponding particle source distribution plan in the system interface for the user to view and adjust the plan.

[0223] Among them, when displaying the planned particle source distribution plan, the processor combines the three-dimensional coordinates of the dangerous tissue areas such as blood vessels / heart recognized during the image recognition process to generate prompt information for the particle source distribution plan. Among them, the prompt information is used to prompt the user of the possible dangerous items in the plan. For example, if the distance between a certain implantation trajectory and the dangerous tissue is relatively close, the prompt information is used to prompt the user which trajectory in the current plan is at risk, and prompt the user to select other planning plans or make manual adjustments to the current plan.

[0224] The above-mentioned source distribution system for implanting particles, on the one hand, first extracts at least one target area from the medical image of the intervention object, and then uses the target source distribution mode selected by the user to perform particle source distribution processing on the at least one target area to configure the implantation trajectory and spatial distribution of the radioactive particles when implanting into the intervention object, thus optimizing the process of particle source distribution processing for implanting particles, and compared with the methods in the prior art, effectively improving the efficiency of particle source distribution with a standardized execution procedure and reducing the consumption of manpower and material resources; on the other hand, through the target source distribution mode selected by the user, under the control operation of the user and / or the program control of the particle source distribution system, perform particle source distribution on the target area of the intervention object to obtain the corresponding particle source distribution result, thereby improving the accuracy and feasibility of particle source distribution for implanting particles and providing more reference information for subsequent medical treatment.

[0225] In one embodiment, the present application provides a display system for implanted particles, which includes a memory and a processor, and the memory stores a computer program.

[0226] Taking the processor in this system applied to Figure 1 as an example for illustration, as shown in Figure 8 and Figure 9 shown, Figure 8 FIG. is a schematic flowchart of a processor of a display system for implanted particles executing a computer program according to an exemplary embodiment. Figure 9 FIG. is a flowchart of another processor of a display system for implanted particles executing a computer program according to an exemplary embodiment. When the above processor executes the computer program, it specifically is used to execute the following steps:

[0227] Step S21: Display a medical image of the intervention object.

[0228] Wherein, the intervention object is a medical diagnosis and treatment object to be subjected to medical intervention treatment.

[0229] In some embodiments, the medical diagnosis and treatment object may be a human object or an animal object, etc.

[0230] In one embodiment, the medical image includes an internal tissue image of the intervention object acquired by a preset imaging method.

[0231] As an example, an intervention object is a human patient object. The processor responds to the user's image upload operation, loads the CT image of the patient object selected by the user into the source placement system, and thus displays the CT image in a three-dimensional image manner on the particle source placement interface. Among them, the loaded CT image includes the first diagnosis image of the patient object (that is, the CT image taken when the patient object is first subjected to medical diagnosis and treatment) and the preoperative image (that is, the CT image taken when the patient object is subjected to medical diagnosis and treatment this time).

[0232] Step S22: In response to the image recognition and image segmentation operations on the medical image, segment at least one target region from the medical image.

[0233] Specifically, the processor displays the medical image in a two-dimensional / three-dimensional image manner on the particle source placement interface for the user to perform image analysis on the medical image, so as to complete operations such as image browsing, image recognition, image segmentation, and region annotation of the medical image, extract the at least one image region segmented as the target region, and fuse and display the extracted target region in the two-dimensional / three-dimensional particle source placement interface for the user to view and annotate and edit.

[0234] In an exemplary embodiment, refer to Figure 10 , Figure 10This is a schematic diagram of an interface for an embodiment of a target region for displaying a medical image in this application. In Figure 10 what is shown in a of Figure 10 is the image recognition of a medical image to identify a tumor lesion, and the three-dimensional image region where the tumor lesion is located is labeled as "lesion region X"; in Figure 10 what is shown in b of Figure 10 is the image segmentation of "lesion region X" in the medical image to segment out three corresponding target regions, and the three target regions are respectively labeled as "X1", "X2", and "X3". Among them, for the target regions "X1", "X2", and "X3" segmented from "lesion region X", they can also be called the labeled regions of "lesion region X", and after obtaining the labeled regions, based on the region labeling operations of the user for each labeled region respectively, annotation editing can be performed in each target region (as shown in b of Figure 11 ), so as to label the corresponding annotation content in the labeled region. Among them, in b of Figure 11 , annotation editing can be performed on the target region "lesion 1", the target region "bone", the target region "low-dose area", and the target region "high-dose area" respectively.

[0235] Among them, the operations of image recognition, image segmentation, and region annotation of the medical image can be manual operations of the user or automatic operations of the processor.

[0236] In some embodiments, the image recognition operation is used to identify the type of tissue region in the medical image. For example, identifying lesion regions of types such as tumors in the medical image, and identifying dangerous regions of types such as blood vessels and vital organs in the medical image.

[0237] In some embodiments, the image segmentation operation is used to segment out relevant tissue regions in the medical image, including image regions of lesion tissue regions in the lungs, liver, etc. Among them, the image segmentation operation of the tissue region can be automatically segmented under the drive of an automatic program of the processor, or manually segmented under the manual planning of the user.

[0238] In some embodiments, the region annotation operation is used to annotate reference information about particle source placement such as the region area, spatial position, and tissue region type corresponding to the segmented image region.

[0239] Step S23: In response to a selection operation for a target source placement pattern corresponding to at least one target region, based on the target source placement pattern, perform particle source placement processing on the at least one target region to obtain a source placement result.

[0240] Specifically, in the particle source placement interface of the source placement system, there are multiple source placement patterns for each target region for the user to choose. Thus, the processor determines the source placement pattern corresponding to each target region based on the user's selection operation.

[0241] Among them, the target source distribution mode is a mode of performing particle source distribution on the intervention object through the control operation of the user and / or the program control of the particle source distribution system.

[0242] Among them, the particle source distribution process is used to configure the implantation trajectory and spatial distribution of radioactive particles when implanted into the intervention object.

[0243] Among them, the trajectory information of the radioactive particles includes at least the trajectory length and trajectory direction of the implantation trajectory; the particle information includes at least the particle position, particle quantity, particle type, and particle activity of the radioactive particles when implanted into the intervention object.

[0244] In some embodiments, the implantation trajectory of the radioactive particles when implanted into the intervention object refers to the implantation path of the radioactive particles when implanted into the intervention object. This implantation path is related to information such as the path length and path direction of the radioactive particles in the intervention object. Thus, the implantation trajectory of the radioactive particles when implanted into the intervention object can be characterized based on the corresponding trajectory information. That is, the particle source distribution process needs to perform path planning on the implantation trajectory of the radioactive particles. Thus, the user can, in the source distribution result, based on the corresponding trajectory information, intuitively understand information such as the path length and path direction of the radioactive particles in the intervention object, so as to facilitate the user's judgment of the particle source distribution processing effect, thereby improving the diagnosis and treatment effect of performing related intervention treatments on the intervention object.

[0245] In some embodiments, the spatial distribution of the radioactive particles refers to the distribution of the radioactive particles in the internal space of the intervention object. This distribution is related to information such as the type, position, quantity, and distribution form of the radioactive particles. Thus, the spatial distribution of the radioactive particles when implanted into the intervention object can be characterized based on the corresponding particle information. That is, the particle source distribution process needs to perform particle planning on the particle information of the radioactive particles. Thus, the user can, in the source distribution result, based on the corresponding particle information, intuitively understand information such as the type, position, quantity, and distribution form of the radioactive particles, so as to facilitate the user's judgment of the particle source distribution processing effect, thereby improving the diagnosis and treatment effect of performing related intervention treatments on the intervention object.

[0246] Among them, the distribution form of the radioactive particles can be in the form of dots, lines, or planes.

[0247] In one embodiment, the source distribution mode includes: a first mode of automatically performing particle source distribution processing on the intervention object under the program control of the particle source distribution system. It can be understood that this first mode is the automatic source distribution mode of using the program control of the particle source distribution system to perform particle source distribution.

[0248] Specifically, for each target region, when the user selects the first mode for the source placement system to automatically perform particle source placement, the processor responds to the program control of the particle source placement system. First, it automatically calculates the volume size, spatial position, and target skin distance of the target region in the object coordinate system. Then, it initializes and sets information such as the type, activity, and quantity of radioactive particles. Then, based on the particle information, preset constraint conditions, and the volume size, spatial position, and target skin distance of the target region, multiple groups of particle source placement plans are planned. Among them, each group of particle source placement plans includes the trajectory information of the planned implantation trajectory and the particle information of the corresponding matched radioactive particles.

[0249] In another embodiment, the source placement mode includes: a second mode in which, under the control operation of the user, particle source placement processing of the intervention object is manually performed. It can be understood that this second mode is a manual source placement mode for performing particle source placement by using the control operation of the user.

[0250] Specifically, for each target region, when the user selects the second mode for the user to manually perform particle source placement, the processor first calculates and displays the volume size, spatial position, and target skin distance of the target region in the object coordinate system. Then, in response to the control operation of the user, the trajectory length and trajectory direction of the implantation trajectory are planned in the target region to obtain the trajectory information. Finally, based on the trajectory information of all implantation trajectories, the influence relationship between the particle information corresponding to each implantation trajectory, preset constraint conditions, and the volume size, spatial position, and target skin distance of the target region, the particle information for each implantation trajectory is respectively planned to obtain a complete particle source placement plan.

[0251] In another embodiment, the source placement mode includes: a third mode in which, under the control operation of the user and the program control of the particle source placement system, particle source placement processing of the intervention object is semi-automatically performed. It can be understood that this third mode is a semi-automatic source placement mode for performing particle source placement by using the control operation of the user and the program control of the particle source placement system.

[0252] Specifically, for each target region, when the user selects the third mode for semi-automatic particle source placement in the source placement system, the processor first calculates and displays the volume size, spatial position, and target skin distance of the target region in the preset coordinate system; then, it initializes and displays particle information such as the type, activity, and quantity of radioactive particles; finally, it responds to the user's regional annotation operations on each target region to determine at least one annotated region in each target region and the corresponding annotation content for the at least one annotated region. Then, after the user completes the regional annotation of the target region, for the unannotated regions in the target region, the processor defaults to the automatic source placement mode and automatically configures the trajectory information and particle information for the unannotated regions to obtain a particle source placement plan for the unannotated regions. Also, for the annotated regions in the target region, the processor responds to the source placement modes independently selected by the user for different annotated regions and configures the trajectory information and particle information for the annotated regions in an automatic / semi-automatic / manual planning manner to obtain a particle source placement plan for the annotated regions.

[0253] Among them, after the processor plans a set of particle source placement plans based on the user's operation control and / or the program control of the particle source placement system in the first mode, the second mode, or the third mode, the user's operation control and / or the program control of the particle source placement system can further adjust the particle source placement plan. Specifically, it can include: first, automatically or manually selecting the first implantation trajectory in the particle source placement plan; then, automatically or manually configuring the particle arrangement information for the first implantation trajectory and displaying the initial isodose field according to the particle arrangement information; then, automatically or manually selecting the second implantation trajectory and automatically or manually configuring the particle arrangement information for the second implantation trajectory; then, updating the initial isodose field based on the particle arrangement information of the second implantation trajectory to obtain an updated isodose field; then, based on the updated isodose field, automatically or manually adjusting the particle information such as the particle position, radiation intensity, and duration in the first implantation trajectory and the second implantation trajectory so that the radiation regions of the radioactive particles planned in the first implantation trajectory and the second implantation trajectory can be comprehensively and evenly covered; finally, automatically or manually cyclically planning the particle arrangement information of each implantation trajectory by analogy until the target region can be comprehensively and evenly covered by the isodose field corresponding to the particle source placement plan.

[0254] Among them, by the user independently selecting the corresponding target source placement mode, it is convenient for the user to flexibly select the corresponding source placement mode for particle source placement according to the actual needs of particle source placement processing, thereby improving the efficiency and flexibility of particle source placement processing.

[0255] In one embodiment, after configuring and planning the target area with respect to trajectory information and particle information to obtain a corresponding particle source distribution plan, if the processor responds that the particle source distribution plan meets the user's requirements, the particle source distribution plan is used as the planning plan to be executed to complete the plan planning; if the processor responds that the particle source distribution plan does not meet the user's requirements, the user can reselect in the system interface to re-plan the target area in the way of automatic planning / semi-automatic planning / manual planning to obtain a new particle source distribution plan; or, the user can also manually adjust the particle source distribution plan of the target area in the system interface to obtain new trajectory information and particle information, thereby obtaining a new particle source distribution plan.

[0256] In one exemplary embodiment, refer to Figure 11 , Figure 11 is a schematic diagram of the interface for manually adjusting a particle source distribution plan in this application. Among them, in Figure 11 a shows the configuration page for the configuration of the radioactive particle therapy project (Treatment Planning System, TPS), and this page is displayed in the system interface in the form of a pop-up window. The user can configure the attribute information of the TPS project in this configuration page, including information such as the "plan name", "planner", "particle activity", "particle type", and "prescription dose" of the project.

[0257] Among them, in Figure 11 b shows the configuration page for configuring the differential display of each image area in the medical image, and this page is displayed in the system interface in the form of a pop-up window. The following are displayed in this configuration page: the area name "lesion 1" of the first type of tissue area, the area names "bone", "low-dose area", and "high-dose area" of the second type of tissue area; "area A" for configuring the background color and transparency of each image area; the attribute information of each image area, including that the area volume of "lesion 1" is "88.5 cm 2 " and the type is "target area", and the area volume of "bone" is "559.4 cm 2 " and the type is "hazardous area"; and the "browse control" and "delete control" configured for each image area. Among them, if the user clicks the "browse control", the system interface jumps to display the two-dimensional / three-dimensional particle source distribution plan of the corresponding area; if the user clicks the "delete control", the processor deletes the corresponding area and its particle source distribution plan.

[0258] Among them, in Figure 11What is shown in C is a configuration page for configuring a certain implantation trajectory and radioactive particles in a source placement scheme for a certain target particle. This page is displayed in the system interface in the form of a pop-up window. In the "First Region" of this configuration page, a schematic diagram of the puncture needle for a certain target implantation trajectory is shown, and in the "Second Region" within the "First Region", a schematic diagram of the spatial positions of the radioactive particles placed in the puncture needle is shown. Among them, a scale bar is shown above the "First Region", which is used to display the puncture depth of the puncture needle and the spacing and positions between the radioactive particles placed in the puncture needle. Among them, the user can, in this configuration page, adjust the puncture depth of the puncture needle, the spacing and positions between the radioactive particles placed in the puncture needle based on the scale bar. What is shown below this configuration page is a schematic diagram of the space of this target particle source placement scheme in the image. Among them, the trajectory information corresponding to this target particle source placement scheme has "Needle Track 1", "Needle Track 2", and "Needle Track 3", as well as the entry points and target points corresponding to each implantation trajectory. As shown in the figure, the entry point of "Needle Track 1" is "P1" and the target point is "P2"; the entry point of "Needle Track 2" is "P3" and the target point is "P4"; the entry point of "Needle Track 3" is "P5" and the target point is "P6".

[0259] Step S24: In the medical image, display the source placement results corresponding to at least one target region.

[0260] Among them, in the source placement results corresponding to each target region in the medical image, there are included at least one set of particle source placement schemes, and this particle source placement scheme is used to characterize the implantation trajectory and particle distribution of the radioactive particles.

[0261] In one embodiment, in terms of displaying the source placement results corresponding to at least one target region, the processor is used to execute the following steps:

[0262] Step 1: In the target region, display at least one set of corresponding particle source placement schemes.

[0263] Among them, different particle source placement schemes have different display attributes.

[0264] Among them, the isodose field corresponding to each set of particle source placement schemes can achieve comprehensive coverage of the target region. That is, in each set of trajectory information, there are included no less than one planned implantation trajectory, and moreover, when the isodose fields corresponding to the particle information configured in each implantation trajectory are merged, the coverage area of the total isodose field can evenly and comprehensively cover the entire lesion region.

[0265] Among them, when the user does not select a certain set of target particle source placement schemes, the processor displays all the particle source placement schemes on the system interface and uses different colors to distinguish different sets of particle source placement schemes.

[0266] Step 2: In response to a selection operation on any target implantation trajectory or target radioactive particle in the target area, highlight the target particle source distribution plan corresponding to the target implantation trajectory or target radioactive particle.

[0267] Wherein, when the user selects the implantation trajectory of a certain set of target particle source distribution plans, the processor highlights all the isodose fields of the implantation trajectories and radioactive particles corresponding to the target particle source distribution plan on the system interface for the user to view.

[0268] In one embodiment, in terms of highlighting the target particle source distribution plan corresponding to the target implantation trajectory or target radioactive particle, the processor is configured to perform: highlighting the implantation trajectory in the target particle source distribution plan; and, displaying the isodose field corresponding to the radioactive particle in the target particle source distribution plan; and, near the target area, displaying the trajectory information and particle information of the radioactive particle in the form of a floating window. Wherein, the isodose field covers the target area.

[0269] In an exemplary embodiment, refer to Figure 12 , Figure 12 is a schematic diagram of an interface showing an embodiment of the target particle source distribution plan in the present application. Wherein, "Needle Track 1", "Needle Track 2" and "Needle Track 3" represent the trajectory information corresponding to the target particle source distribution plan, which includes the needle insertion points and target points corresponding to the implantation trajectory, and the black blocks in each needle track represent the spatial position information of the radioactive particles placed in the needle track; and, near the implantation trajectory, information such as the area and position of the target area, trajectory length, trajectory direction, etc. and particle activity, position, etc. are displayed. Wherein, if the distance between the target area and the radioactive particle is smaller, the radiation intensity of its corresponding isodose field is greater, and conversely, if the distance between the target area and the radioactive particle is larger, the radiation intensity of its corresponding isodose field is smaller. As Figure 12 shown, "Region 1", "Region 2" and "Region 3" represent the isodose fields corresponding to each radioactive particle, and "Region 1" is at the target point position of each needle track, and the radiation intensity corresponding to its isodose field is the strongest; "Region 2" is in the outermost first layer of "Region 1", and the radiation intensity corresponding to its isodose field is weaker than that of "Region 1"; "Region 3" is in the outermost second layer of "Region 1", and the radiation intensity corresponding to its isodose field is the weakest. Wherein, when displaying the isodose field corresponding to the radioactive particle, different colors or brightness levels can also be displayed for the target area covered by the isodose field to represent the different radiation intensities corresponding to its isodose field. As shown in Figure 12 , the radiation intensities corresponding to "Region 1", "Region 2" and "Region 3" are different, and their brightness levels displayed in the interface are also different.

[0270] In one embodiment, regarding using different colors to represent the radiation intensity of the target area covered by the isodose field, a radiation intensity comparison table for the isodose field can also be displayed in a pop-up window on the interface. As shown in Figure 12 the "isodose line" shown in Figure 12 , the "isodose line" includes a list of radiation intensity ranges, and different colors are used to distinguish the table areas corresponding to different radiation intensity ranges in the list of radiation intensity ranges. Among them, if different colors are used to represent the radiation intensity of the target area covered by the isodose field, the display color of the target area is set to be the same as the color used for the table area corresponding to its corresponding radiation intensity range.

[0271] Among them, by displaying and highlighting different particle source placement schemes in different colors as described above, it is convenient for users to clearly distinguish and analyze various different particle source placement schemes, thereby improving the accuracy and safety during subsequent interventional treatment of the intervention object.

[0272] In one embodiment, after displaying the source placement results corresponding to at least one target area, the processor is further configured to perform the following steps:

[0273] Step 1: Generate a prompt message in response to the configured trajectory information and / or particle information not meeting the preset constraint conditions.

[0274] Among them, the prompt message is used to prompt the user to change the target source placement mode or modify the configured trajectory information and particle information.

[0275] Step 2: Display the prompt message in a pop-up window near the source placement result.

[0276] In one embodiment, when displaying each group of particle source placement schemes, the processor combines the three-dimensional coordinates of dangerous tissue areas such as blood vessels / heart recognized during image recognition to detect whether the trajectory information and particle information configured by the user and / or the system meet the preset constraint conditions, and generates a prompt message corresponding to the trajectory information and / or particle information in the case where the trajectory information and / or particle information do not meet the preset constraint conditions. Among them, the prompt message is used to prompt the user about possible dangerous items in the scheme. For example, if the distance between a certain implantation trajectory and a dangerous tissue is relatively close, the prompt message is used to prompt the user which trajectory in the current scheme has risks, and prompt the user to select other planning schemes or manually adjust the current scheme.

[0277] Among them, by performing dangerous prompts and re-planning on the particle source placement scheme as described above, it is convenient for users to adjust the particle source placement scheme in a timely and accurate manner, thereby improving the accuracy and safety during subsequent interventional treatment of the intervention object.

[0278] In some embodiments, the prompt information displayed in the form of a pop-up window may be to pop up and display the prompt information from the interface in the form of a transparent bubble, or to pop up and display the prompt information from the interface in the form of a virtual dialog box, etc., which is not specifically limited here.

[0279] For the above-mentioned radioactive seed implantation display system, on the one hand, at first, at least one target region is identified and segmented from the displayed medical image, and then the at least one target region is processed for radioactive seed source placement by using the target source placement mode selected by the user, so as to configure the implantation trajectory and spatial distribution of the radioactive seeds when implanting into the intervention object, thereby optimizing the process of radioactive seed source placement processing. Compared with the existing technology, the efficiency of radioactive seed source placement is effectively improved with a standardized execution procedure, and the consumption of manpower and material resources is reduced. On the other hand, through the target source placement mode selected by the user, under the control operation of the user and / or the program control of the radioactive seed source placement system, radioactive seed source placement is performed on the target region of the intervention object and the corresponding radioactive seed source placement result is displayed, which improves the accuracy and feasibility of radioactive seed source placement and provides more reference information for subsequent medical treatment.

[0280] It should be understood that although Figures 2 - 12 the steps in the flowchart of Figures 2 - 12 are displayed in sequence according to the arrows, these steps are not necessarily executed in the order indicated by the arrows. Unless there is a clear description in this article, there is no strict order limit for the execution of these steps, and these steps can be executed in other orders. Moreover,

[0281] It can be understood that the same / similar parts between the various embodiments of the above two systems in this specification can be referred to each other. Each embodiment focuses on the differences from other embodiments, and for the relevant parts, refer to the descriptions of other method embodiments.

[0282] In one embodiment, a radioactive seed source placement method provided by an embodiment of the present application is applied to the processor of a radioactive seed source placement system. The method specifically includes the following content:

[0283] Step 1: Obtain the medical image of the intervention object.

[0284] Step 2: Extract at least one target region from the medical image.

[0285] Step 3: In response to a user operation, determine a target mode applied to at least one target area from a variety of preset source distribution modes.

[0286] Among them, the source distribution mode is a way of performing particle source distribution on an intervention object through the control operation of the user and / or the program control of the particle source distribution system.

[0287] Step 4: Based on the target mode, perform particle source distribution processing on at least one target area to obtain a source distribution result; the particle source distribution processing is used to configure the implantation trajectory and spatial distribution of radioactive particles when implanting them into an intervention object.

[0288] Among them, the source distribution mode includes a first mode, which is used to perform particle source distribution processing on an intervention object under the program control of the particle source distribution system.

[0289] In some embodiments, in terms of performing particle source distribution processing on at least one target area based on the target mode, the processor is further configured to perform the following steps:

[0290] Step 1: When the target mode is the first mode, in response to the program control of the particle source distribution system, configure multiple sets of trajectory information for at least one target area and multiple sets of corresponding matching particle information based on preset source distribution rules;

[0291] Step 2: Determine target trajectory information and corresponding matching target particle information from the multiple sets of trajectory information and the multiple sets of corresponding matching particle information.

[0292] Among them, the source distribution mode includes a second mode, which is used to perform particle source distribution processing on an intervention object under the control operation of the user.

[0293] In some embodiments, in terms of performing particle source distribution processing on at least one target area based on the target mode, the processor is further configured to perform the following steps:

[0294] Step 1: When the target mode is the second mode, in response to the control operation of the user, configure trajectory information for at least one target area.

[0295] Step 2: In response to the program control of the particle source distribution system, configure particle information for at least one target area based on the preset source distribution rules and the trajectory information.

[0296] Among them, the source distribution mode includes a third mode, which is used to perform particle source distribution processing on an intervention object under the control operation of the user and the program control of the particle source distribution system.

[0297] In some embodiments, in terms of performing particle source distribution processing on at least one target area based on a target pattern, the processor is further configured to perform the following steps:

[0298] Step 1: When the target pattern is the third pattern, based on the user's annotation operation for at least one target area, at least one annotation area is divided in the target area, and corresponding annotation content is marked in the at least one annotation area.

[0299] Step 2: For the unannotated areas in the target area, in response to the program control of the particle source distribution system, trajectory information and particle information for the unannotated areas are configured based on preset source distribution rules; and for the at least one annotation area, in response to the user's control operation and / or the program control of the particle source distribution system, trajectory information and particle information for the annotation area are configured based on the annotation content.

[0300] In some embodiments, in terms of configuring corresponding trajectory information and particle information based on preset source distribution rules, the processor is further configured to perform the following steps:

[0301] Step 1: Based on the target points in the target area, multiple candidate implantation trajectories for the target area are obtained.

[0302] Step 2: Under the limitation of a preset first constraint condition, based on the volume, spatial position of the target area, and the target skin distances of each candidate implantation trajectory, at least one target implantation trajectory is selected from the multiple candidate trajectories to obtain corresponding trajectory information.

[0303] Step 3: Under the limitation of a preset second constraint condition, corresponding particle information is configured based on the volume, spatial position, and trajectory information.

[0304] Wherein, the particle information is used to characterize the spatial distribution of radioactive particles when implanted into an intervention object.

[0305] Wherein, the target area is a first type of tissue area in the intervention object that is marked and spans multiple object cross-sections, and in the intervention object, there is also a second type of tissue area that is marked and spans multiple object cross-sections.

[0306] In some embodiments, in terms of screening out at least one target implantation trajectory that meets the constraint conditions, the processor is further configured to: under the limitation of the first constraint condition, screen out at least one target implantation trajectory from the candidate implantation trajectories.

[0307] Wherein, the first constraint condition includes a first sub-constraint condition, a second sub-constraint condition, and a third sub-constraint condition.

[0308] Among them, the first sub-constraint condition is used to limit the cross-layer angle of the trajectory direction of the target implantation trajectory when crossing the object cross-sections of different plane layers to be less than or equal to a preset angle.

[0309] Among them, the second sub-constraint condition is used to limit the trajectory length of the target implantation trajectory to be less than or equal to a preset length.

[0310] Among them, the third sub-constraint condition is used to limit the distance between the target implantation trajectory and the second type of tissue region to be greater than or equal to a preset distance.

[0311] In some embodiments, in terms of configuring the corresponding particle information, the processor is further configured to perform: under the limitation of the second constraint condition, configure the particle position, particle number, particle type, and particle activity of the radioactive particles in at least one implantation trajectory.

[0312] Among them, the second constraint condition includes a fourth sub-constraint condition, a fifth sub-constraint condition, and a sixth sub-constraint condition.

[0313] Among them, the fourth sub-constraint condition is used to limit the distance between the radiation range corresponding to the radioactive particles and the second type of tissue region to be greater than or equal to a preset distance.

[0314] Among them, the fifth sub-constraint condition is used to limit the distance between two adjacent radioactive particles to be greater than or equal to a preset distance.

[0315] Among them, the sixth sub-constraint condition is used to limit the particle activity to be less than or equal to a preset activity.

[0316] In one embodiment, a method for displaying implanted particles provided by an embodiment of the present application is applied to a processor of a display system for implanted particles. The method specifically includes the following contents:

[0317] Step 1: Display medical images of the intervention object.

[0318] Step 2: In response to image recognition and image segmentation operations on the medical images, at least one target region is segmented from the medical images.

[0319] Step 3: In response to a selection operation for the target source distribution mode corresponding to at least one target region, based on the target source distribution mode, particle source distribution processing is performed on at least one target region to obtain a source distribution result; the target source distribution mode is a method of performing particle source distribution on the intervention object through user control operations and / or program control of the particle source distribution system; the particle source distribution processing is used to configure the implantation trajectory and spatial distribution of radioactive particles when implanting into the intervention object.

[0320] Step 4: In the medical images, display the source distribution result corresponding to at least one target region.

[0321] Among them, in the source distribution result corresponding to the target area, there is at least one set of particle source distribution schemes, and the particle source distribution scheme is used to characterize the implantation trajectory of radioactive particles and the particle distribution.

[0322] In some embodiments, in terms of displaying the source distribution result corresponding to at least one target area, the processor is further configured to perform the following steps:

[0323] Step 1: In the target area, display at least one corresponding set of particle source distribution schemes.

[0324] Among them, different particle source distribution schemes have different display attributes.

[0325] Step 2: In response to a selection operation on any target implantation trajectory or target radioactive particle in the target area, highlight the target particle source distribution scheme corresponding to the target implantation trajectory or target radioactive particle.

[0326] In some embodiments, in terms of highlighting the target particle source distribution scheme corresponding to the target implantation trajectory or target radioactive particle, the processor is further configured to perform the following steps: highlight the implantation trajectory in the target particle source distribution scheme; and display the isodose field corresponding to the radioactive particles in the target particle source distribution scheme; wherein, the isodose field covers the target area; and near the target area, display the trajectory information and particle information of the radioactive particles in the form of a floating window.

[0327] In some embodiments, after displaying the source distribution result corresponding to at least one target area, the processor is further configured to perform the following steps:

[0328] Step 1: In response to the configured trajectory information and / or particle information not meeting the preset constraint conditions, generate a prompt message.

[0329] Among them, the prompt message is used to prompt the user to change the target source distribution mode or modify the configured trajectory information and particle information.

[0330] Step 2: Near the source distribution result, display the prompt message in the form of a pop-up window.

[0331] Figure 13 It is a block diagram of a source distribution device for implanting particles provided by an embodiment of the present application. Refer to Figure 13 , the source distribution device 10 for implanting particles includes: an image acquisition module 11, a region extraction module 12, a source distribution mode module 13, and a particle source distribution module 14.

[0332] Among them, the image acquisition module 11 is used to acquire medical images of the intervention object;

[0333] Among them, the region extraction module 12 is used to extract at least one target region from the medical image;

[0334] Among them, the source pattern module 13 is used to determine, in response to a user operation, a target pattern applied to the at least one target region from a variety of preset source patterns; the source pattern is a way of performing particle source distribution on the intervention object through the user's control operation and / or the program control of the particle source distribution system;

[0335] Among them, the particle source distribution module 14 is used to perform particle source distribution processing on the at least one target region based on the target pattern to obtain a source distribution result; the particle source distribution processing is used to configure the implantation trajectory and spatial distribution of radioactive particles when implanting the intervention object.

[0336] Figure 14 It is a block diagram of a display device for implanting particles provided by an embodiment of the present application. Refer to Figure 14 As shown in the figure, the display device 10A for implanting particles includes: an image display module 11A, a region segmentation module 12A, a particle source distribution module 13A, and a result display module 14A.

[0337] Among them, the image display module 11A is used to display a medical image of an intervention object;

[0338] Among them, the region segmentation module 12A is used to segment at least one target region from the medical image in response to an image recognition and image segmentation operation on the medical image;

[0339] Among them, the particle source distribution module 13A is used to perform particle source distribution processing on the at least one target region based on the target source distribution pattern in response to a selection operation for the target source distribution pattern corresponding to the at least one target region, to obtain a source distribution result; the target source distribution pattern is a way of performing particle source distribution on the intervention object through the user's control operation and / or the program control of the particle source distribution system; the particle source distribution processing is used to configure the implantation trajectory and spatial distribution of radioactive particles when implanting the intervention object;

[0340] Among them, the result display module 14A is used to display the source distribution result corresponding to the at least one target region in the medical image.

[0341] Figure 15 It is a block diagram of a computer device 20 provided by an embodiment of the present application. For example, the computer device 20 can be an electronic device, an electronic component, or a server array, etc. Refer to Figure 15, the computer device 20 includes a processor 21, and the processor 21 may further be a set of processors, which may include one or more processors. The computer device 20 also includes memory resources represented by a memory 22, where a computer program, such as an application program, is stored on the memory 22. The computer program stored in the memory 22 may include one or more modules each corresponding to a set of executable instructions. In addition, the processing component 21 is configured to implement the source placement method of implanted particles or the display method of implanted particles as described above when executing the computer program.

[0342] In some embodiments, the computer device 20 is an electronic device, and the computing system in the electronic device can run one or more operating systems, including any of the operating systems discussed above and any commercial server operating system. The computer device 20 can also run any one of various additional server applications and / or middleware applications, including HTTP (HyperText Transfer Protocol) servers, FTP (File Transfer Protocol) servers, CGI (Common Gateway Interface) servers, superservers, database servers, etc. Exemplary database servers include, but are not limited to, database servers commercially available from (International Business Machines), etc.

[0343] In some embodiments, the processing component 21 generally controls the overall operation of the computer device 20, such as operations associated with display, data processing, data communication, and recording operations. The processor 21 may include one or more processor components to execute the computer program to complete all or part of the steps of the above-described method. In addition, the processor component may include one or more modules to facilitate the interaction between the processor component and other components. For example, the processor component may include a multimedia module to facilitate controlling the interaction between the user computer device 20 and the processor 21 using the multimedia component.

[0344] In some embodiments, the processor component in the processor 21 may also be referred to as a CPU (Central Processing Unit). The processor component may be an electronic chip with the ability to process signals. The processor may also be a general-purpose processor, a digital signal processor (DSP), an application-specific integrated circuit (ASIC), an application-specific integrated circuit (ASIC), a field-programmable gate array (FPGA), or other programmable logic devices, discrete gate or transistor logic devices, discrete hardware components. The general-purpose processor may be a microprocessor or the processor may also be any conventional processor component, etc. Additionally, the processor component may be implemented jointly by integrated circuit chips.

[0345] In some embodiments, the memory 22 is configured to store various types of data to support the operation of the computer device 20. Examples of such data include instructions for any application or method operating on the computer device 20, acquired data, messages, pictures, videos, etc. The memory 22 may be implemented by any type of volatile or non-volatile storage device or a combination thereof, such as static random access memory (SRAM), electrically erasable programmable read-only memory (EEPROM), erasable programmable read-only memory (EPROM), programmable read-only memory (PROM), read-only memory (ROM), magnetic memory, flash memory, magnetic disks, optical disks, or graphene memory.

[0346] In some embodiments, the memory 22 may be a memory module, a TF card, etc., and can store all the information in the computer device 20. The input raw data, computer programs, intermediate operation results, and final operation results are all stored in the memory 22. In some embodiments, it stores and retrieves information according to the locations specified by the processor. In some embodiments, with the memory 22, the computer device 20 has the memory function and can ensure normal operation. In some embodiments, the memory 22 of the computer device 20 can be classified into a main memory (internal memory) and an auxiliary memory (external memory) according to its use, or there is also a classification method of dividing it into an external memory and an internal memory. The external memory is usually a magnetic medium or an optical disk, etc., which can store information for a long time. The internal memory refers to the storage component on the motherboard, which is used to store the data and programs being currently executed, but only temporarily stores the programs and data. When the power is turned off or interrupted, the data will be lost.

[0347] In some embodiments, the computer device 20 may further include: a power supply component 23 configured to perform power management of the computer device 20, a wired or wireless network interface 24 configured to connect the computer device 20 to a network, and an input / output (I / O) interface 25. The computer device 20 may operate based on an operating system stored in the memory 22, such as Windows Server, Mac OS X, Unix, Linux, FreeBSD, or the like.

[0348] In some embodiments, the power supply component 23 provides power to various components of the computer device 20. The power supply component 23 may include a power management system, one or more power supplies, and other components associated with generating, managing, and distributing power for the computer device 20.

[0349] In some embodiments, the wired or wireless network interface 24 is configured to facilitate wired or wireless communication between the computer device 20 and other devices. The computer device 20 may access a wireless network based on a communication standard, such as WiFi, a carrier network (such as 2G, 3G, 4G, or 5G), or a combination thereof.

[0350] In some embodiments, the wired or wireless network interface 24 receives broadcast signals or broadcast-related information from an external broadcast management system via a broadcast channel. In an exemplary embodiment, the wired or wireless network interface 24 further includes a near field communication (NFC) module to facilitate short-range communication. For example, the NFC module may be implemented based on radio frequency identification (RFID) technology, infrared data association (IrDA) technology, ultra-wideband (UWB) technology, Bluetooth (BT) technology, and other technologies.

[0351] In some embodiments, the input / output (I / O) interface 25 provides an interface between the processor 21 and a peripheral interface module, and the peripheral interface module may be a keyboard, a click wheel, buttons, etc. These buttons may include, but are not limited to: a home button, a volume button, a start button, and a lock button.

[0352] Figure 16 It is a block diagram of a computer-readable storage medium 30 provided by an embodiment of the present application. A computer program 31 is stored on the computer-readable storage medium 30, and when the computer program 31 is executed by a processor, it implements the source placement method for implanted particles or the display method for implanted particles as described above.

[0353] If the units integrated in each functional unit in various embodiments of the present application are implemented in the form of software functional units and sold or used as independent products, they can be stored in the computer-readable storage medium 30. Based on such an understanding, the technical solution of the present application, in essence, or the part that contributes to the prior art, or all or part of the technical solution, can be embodied in the form of a software product. The computer-readable storage medium 30 contains a computer program 31 including several instructions to enable a computer device (which can be a personal computer, a system server, or a network device, etc.), an electronic device (such as an MP3, an MP4, etc., can also be an intelligent terminal such as a mobile phone, a tablet computer, a wearable device, etc., or a desktop computer, etc.) or a processor to execute all or part of the steps of the methods in various embodiments of the present application.

[0354] Figure 17 It is a block diagram of a computer program product 40 provided by an embodiment of the present application. The computer program product 40 includes program instructions 41, and the program instructions 41 can be executed by the processor of the server 20 to implement the source placement method for implanting seeds or the display method for implanting seeds as described above.

[0355] Those skilled in the art should understand that the embodiments of the present application can provide a source placement system for implanting seeds, a display system for implanting seeds, a source placement method for implanting seeds, a display method for implanting seeds, a source placement device 10 for implanting seeds, a display device 10A for implanting seeds, a computer device 20, a computer-readable storage medium 30 or a computer program product 40. Therefore, the present application can adopt the form of a complete hardware embodiment, a complete software embodiment or an embodiment combining software and hardware aspects. Moreover, the present application can adopt the form of a computer program product 40 implemented on one or more computer program instructions 41 (including but not limited to disk memories, CD-ROMs, optical memories, etc.) containing computer-usable program codes.

[0356] The present application is described with reference to the flowcharts and / or block diagrams of a source placement system for implanting seeds, a display system for implanting seeds, a source placement method for implanting seeds, a display method for implanting seeds, a source placement device 10 for implanting seeds, a display device 10A for implanting seeds, a computer device 20, a computer-readable storage medium 30 or a computer program product 40 in the embodiments of the present application. It should be understood that each process and / or block in the flowchart and / or block diagram, as well as the combination of processes and / or blocks in the flowchart and / or block diagram, can be implemented by the computer program product 40. These computer program products 40 can be provided to the processor of a general-purpose computer, a special-purpose computer, an embedded processor or other programmable data processing devices to generate a machine, so that the program instructions 41 executed by the processor of the computer or other programmable data processing devices generate for implementation in the processFigure One one or more processes and / or blocks Figure One a device for the functions specified in one or more blocks

[0357] These computer program products 40 can also be stored in a computer-readable memory that can direct a computer or other programmable data processing device to work in a specific manner, such that the program instructions 41 stored in the computer program product 40 produce a manufactured article including an instruction device that implements the functions in the process Figure One one or more processes and / or blocks Figure One specified in one or more blocks

[0358] These program instructions 41 can also be loaded onto a computer or other programmable data processing device, such that a series of operation steps are performed on the computer or other programmable device to generate a computer-implemented process, so that the program instructions 41 executed on the computer or other programmable device provide steps for implementing the functions specified in the process Figure One one or more processes and / or blocks Figure One specified in one or more blocks

[0359] It should be noted that the above-mentioned various methods, devices, electronic devices, computer-readable storage media, computer program products, etc. may also include other implementation manners according to the description of the method embodiments. The specific implementation manners can refer to the description of the relevant method embodiments and will not be elaborated here one by one

[0360] Those skilled in the art will readily conceive of other embodiments of the present disclosure after considering the specification and practicing the invention disclosed herein. The present disclosure is intended to cover any variations, uses, or adaptations of the present disclosure that follow the general principles of the present disclosure and include known common knowledge or conventional technical means in the technical field not disclosed in the present disclosure. The specification and embodiments are only regarded as exemplary, and the true scope and spirit of the present disclosure are pointed out by the claims

[0361] It should be understood that the present disclosure is not limited to the exact structures described above and shown in the drawings, and various modifications and changes can be made without departing from its scope. The scope of the present disclosure is only limited by the appended claims

Claims

1. An implanted particle source distribution system, characterized in that, The system includes a processor, and the processor is configured to: Obtain a medical image of the intervention object; Extract at least one target region from the medical image; In response to a user operation, determine a target mode applied to the at least one target region from a variety of preset source distribution modes; the source distribution mode is a manner of performing particle source distribution on the intervention object through the user's control operation and / or the program control of the particle source distribution system; Based on the target mode, perform particle source distribution processing on the at least one target region to obtain a source distribution result; the particle source distribution processing is used to configure the implantation trajectory and spatial distribution of radioactive particles when implanting them into the intervention object.

2. The system according to claim 1, wherein The source distribution mode includes a first mode; In terms of performing particle source distribution processing on the at least one target region based on the target mode, the processor is configured to: When the target mode is the first mode, in response to the program control of the particle source distribution system, based on a preset source distribution rule, configure multiple sets of trajectory information and corresponding and matching multiple sets of particle information for the at least one target region; Based on the multiple sets of trajectory information and the corresponding and matching multiple sets of particle information, determine target trajectory information and corresponding and matching target particle information.

3. The system according to claim 1, characterized in that, The source distribution mode includes a second mode; In terms of performing particle source distribution processing on the at least one target region based on the target mode, the processor is configured to: When the target mode is the second mode, in response to the user's control operation, configure trajectory information for the at least one target region; In response to the program control of the particle source distribution system, based on the preset source distribution rule and the trajectory information, configure particle information for the at least one target region.

4. The system according to claim 1, wherein The source distribution mode includes a third mode; In terms of performing particle source distribution processing on the at least one target region based on the target mode, the processor is configured to: When the target mode is the third mode, based on the user's annotation operation for the at least one target region, divide at least one annotation region in the target region, and annotate corresponding annotation content in the at least one annotation region; For the unannotated region in the target region, in response to the program control of the particle source distribution system, based on a preset source distribution rule, configure trajectory information and particle information for the unannotated region; And For the at least one annotation region, in response to the user's control operation and / or the program control of the particle source distribution system, based on the annotation content, configure trajectory information and particle information for the annotation region.

5. The system according to any one of claims 2-4, characterized in that, In terms of configuring corresponding trajectory information and particle information based on a preset source distribution rule, the processor is configured to: Based on the target points in the target region, obtain multiple candidate implantation trajectories for the target region; Under the limitation of a preset first constraint condition, based on the volume, spatial position of the target region, and the target skin distance of each of the multiple candidate implantation trajectories, screen out at least one target implantation trajectory from the multiple candidate trajectories to obtain corresponding trajectory information; Under the limitation of a preset second constraint condition, corresponding particle information is configured based on the volume, the spatial position, and the trajectory information. The particle information is used to characterize the spatial distribution of the radioactive particles when implanted into the intervention object.

6. An implanted particle display system, characterized in that, The system includes a processor, and the processor is configured to: Display a medical image of an intervention object; In response to an image recognition and image segmentation operation on the medical image, segment at least one target region from the medical image; In response to a selection operation for a target source distribution pattern corresponding to the at least one target region, perform particle source distribution processing on the at least one target region based on the target source distribution pattern to obtain a source distribution result; The target source distribution pattern is a way to perform particle source distribution on the intervention object through user control operations and / or program control of the particle source distribution system; the particle source distribution processing is used to configure the implantation trajectory and spatial distribution of radioactive particles when implanted into the intervention object; In the medical image, display the source distribution result corresponding to the at least one target region.

7. The system according to claim 6, wherein In the source distribution result corresponding to the target region, there are included at least one set of particle source distribution schemes, and the particle source distribution scheme is used to characterize the implantation trajectory and particle distribution of the radioactive particles; Regarding the aspect of displaying the source distribution result corresponding to the at least one target region, the processor is configured to: In the target region, display the corresponding at least one set of particle source distribution schemes; wherein, different particle source distribution schemes have different display attributes; In response to a selection operation for any target implantation trajectory or target radioactive particle in the target region, highlight the target particle source distribution scheme corresponding to the target implantation trajectory or the target radioactive particle.

8. The system according to claim 7, wherein Regarding the aspect of highlighting the target particle source distribution scheme corresponding to the target implantation trajectory or the target radioactive particle, the processor is configured to: Highlight the implantation trajectory in the target particle source distribution scheme; and Display the isodose field corresponding to the radioactive particles in the target particle source distribution scheme; wherein, the isodose field covers the target region; and Near the target region, display the trajectory information and particle information of the radioactive particles in the form of a floating window.

9. The system according to claim 7, wherein After displaying the source distribution result corresponding to the at least one target region, the processor is further configured to: In response to the configured trajectory information and / or particle information not meeting the preset constraint conditions, generate a prompt message; the prompt message is used to prompt the user to change the target source distribution pattern or modify the configured trajectory information and particle information; Near the source distribution result, display the prompt message in the form of a pop-up window.

10. A method for implanting particle source, characterized in that, The method is applied to a particle implantation source distribution system, and the method includes: Obtain a medical image of an intervention object; Extract at least one target region from the medical image; In response to a user operation, determine a target mode applied to the at least one target region from a variety of preset source distribution modes; the source distribution mode is a way of performing particle source distribution on the intervention object through the user's control operation and / or the program control of the particle source distribution system. Based on the target mode, perform particle source distribution processing on the at least one target region to obtain a source distribution result; the particle source distribution processing is used to configure the implantation trajectory and spatial distribution of radioactive particles when implanting into the intervention object.

11. A display method of implanted particles, characterized in that, The method is applied to a display system for implanting particles, and the method includes: Display a medical image of the intervention object. In response to an image recognition and image segmentation operation on the medical image, segment at least one target region from the medical image. In response to a selection operation for the target source distribution mode corresponding to the at least one target region, based on the target source distribution mode, perform particle source distribution processing on the at least one target region to obtain a source distribution result; the target source distribution mode is a way of performing particle source distribution on the intervention object through the user's control operation and / or the program control of the particle source distribution system; the particle source distribution processing is used to configure the implantation trajectory and spatial distribution of radioactive particles when implanting into the intervention object. In the medical image, display the source distribution result corresponding to the at least one target region.

12. A computer device, characterized in that, Includes: A processor; A memory for storing executable instructions of the processor; Wherein, the processor is configured to execute the executable instructions to implement the particle implantation source distribution method according to claim 10, or the particle implantation display method according to claim 11.

13. A computer-readable storage medium, the computer-readable storage medium including program data, characterized in that, When the program data is executed by the processor of the computer device, the computer device can execute the particle implantation source distribution method according to claim 10, or the particle implantation display method according to claim 11.

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