Medication composition of plant estrogens for treating colpitis

Abstract

A composite vegetative estrin medicine in the form of suppository, gel or film for treating vagititis and improving the toughness of vagina and its resistance to bacteria is proportionally prepared from vegetative estrin, cnidiadin, borneol, and at least one of matrine, phellodendrine, berberine, etc and their physiocologically acceptable salts.

Description

technical field

[0001] The invention relates to a herbal medicine composition, in particular to a herbal medicine composition for vaginitis. Background technique

[0002] At present, the medicine for the treatment of women's vaginitis is mainly based on Western medicine, mostly suppositories and ointments that produce local effects. Such as chlorhexidine acetate suppository, Shuangzotai suppository and ointment, among them, chlorhexidine acetate suppository is mainly used for sterilization and anti-inflammation, which is suitable for bacterial vaginosis, but it has no obvious effect on gynecological mixed infection and is more irritating. Shuangzotai suppository and ointment are effective for various vaginitis, but less effective for bacterial vaginosis.

[0003] Mycotic vaginitis is one of the common gynecological diseases. About 80% to 90% of mycotic vaginitis is caused by Candida albicans infection; 10% to 20% are other Candida and Torulopsis infections. Candida albican...

Examples

Embodiment 1

[0022] Extraction method of Pueraria total flavonoids:

[0023] Take pueraria root powder, add water to decoct twice, each time add 10 times of raw material water, cook for 3 hours each time, combine the decoction liquid, let it pass through the macroporous resin, wash with water, 10%, 30%, 50% ethanol in turn Take off, collect and dry total flavonoids.

Embodiment 2

[0025] Extraction method of total flavonoids of Epimedium:

[0026] Take the coarse powder of Epimedium, add water to decoct twice, each time add 10 times the raw material water, boil for 3 hours each time, combine the decoction liquid, let it pass through the macroporous resin, water in turn, 10%, 30%, 50% Eluted with ethanol, collected and dried total flavonoids of Epimedium.

Embodiment 3

[0028] Extraction method of total coumarin from Fructus Cnidii:

[0029] Take the coarse powder of Fructus Cnidii, add 95% ethanol to reflux and extract twice, each time add 95% ethanol 10 times as much as the raw material, extract for 3 hours each time, recover ethanol, and refine the total coumarin of Fructus Cnidii.

[0030] The components and weight of Embodiment 4 to Embodiment 23 are expressed in Table 1.

[0031] Example 4

technical field

[0001] The invention relates to a herbal medicine composition, in particular to a herbal medicine composition for vaginitis. Background technique

[0002] At present, the medicine for the treatment of women's vaginitis is mainly based on Western medicine, mostly suppositories and ointments that produce local effects. Such as chlorhexidine acetate suppository, Shuangzotai suppository and ointment, among them, chlorhexidine acetate suppository is mainly used for sterilization and anti-inflammation, which is suitable for bacterial vaginosis, but it has no obvious effect on gynecological mixed infection and is more irritating. Shuangzotai suppository and ointment are effective for various vaginitis, but less effective for bacterial vaginosis.

[0003] Mycotic vaginitis is one of the common gynecological diseases. About 80% to 90% of mycotic vaginitis is caused by Candida albicans infection; 10% to 20% are other Candida and Torulopsis infections. Candida albican...

Examples

Embodiment 1

[0022] Extraction method of Pueraria total flavonoids:

[0023] Take pueraria root powder, add water to decoct twice, each time add 10 times of raw material water, cook for 3 hours each time, combine the decoction liquid, let it pass through the macroporous resin, wash with water, 10%, 30%, 50% ethanol in turn Take off, collect and dry total flavonoids.

Embodiment 2

[0025] Extraction method of total flavonoids of Epimedium:

[0026] Take the coarse powder of Epimedium, add water to decoct twice, each time add 10 times the raw material water, boil for 3 hours each time, combine the decoction liquid, let it pass through the macroporous resin, water in turn, 10%, 30%, 50% Eluted with ethanol, collected and dried total flavonoids of Epimedium.

Embodiment 3

[0028] Extraction method of total coumarin from Fructus Cnidii:

[0029] Take the coarse powder of Fructus Cnidii, add 95% ethanol to reflux and extract twice, each time add 95% ethanol 10 times as much as the raw material, extract for 3 hours each time, recover ethanol, and refine the total coumarin of Fructus Cnidii.

[0030] The components and weight of Embodiment 4 to Embodiment 23 are expressed in Table 1.

[0031] Example 4